Hub : Genes

LOC134479803

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability LOC134479803 0.34 0.14 0.0e+00 0.26 0.31 0.31 0.31 4.3e-29 5.2e-35 3.3e-35 2.2e-35
2 Liver isoform ratio XM_063264471.1 0.61 0.2 0.0e+00 0.3 0.28 0.3 0.3 2.8e-34 1.9e-31 3.8e-33 6.5e-34
3 Liver isoform ratio XM_063264472.1 0.46 0.22 0.0e+00 0.28 0.26 0.27 0.27 1.4e-30 2.8e-28 1.5e-29 3.6e-30
4 Liver intron excision ratio chr7_1008057_1010740 0.75 0.13 0.0e+00 0.42 0.39 0.43 0.42 5.6e-50 3.5e-46 2.7e-51 3.6e-50
5 Liver intron excision ratio chr7_1010903_1014127 0.79 0.09 0.0e+00 0.39 0.37 0.41 0.4 5.0e-46 7.7e-43 9.5e-49 1.7e-47
6 Liver intron excision ratio chr7_1017346_1026966 0.59 0.18 0.0e+00 0.38 0.4 0.42 0.41 3.6e-45 6.8e-47 1.7e-50 1.4e-48
7 Liver gene expression LOC134479803 0.48 0.14 0.0e+00 0.28 0.28 0.31 0.3 1.3e-31 8.4e-32 6.1e-35 2.6e-34
8 Liver intron excision ratio chr7_1017346_1026327 0.65 0.16 0.0e+00 0.36 0.39 0.41 0.4 2.5e-42 9.2e-46 2.9e-49 6.4e-48

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density1.01.93.6-0.2-1.01.01.3-1.41.7-1.7-1.9
Area under the delay curve0.00.00.1-0.0-0.10.10.2-0.20.1-0.2-0.1
BMI with tail7.024.530.6-5.5-5.35.35.0-4.84.6-4.6-4.4
BMI without tail0.94.66.6-2.6-2.52.52.2-2.11.6-1.7-1.6
Body weight0.62.74.6-2.1-2.02.01.7-1.51.2-1.2-1.0
Weight adjusted by age0.00.10.30.20.3-0.3-0.40.4-0.40.60.4
Bone surface1.22.34.90.2-0.90.91.3-1.61.9-2.1-2.2
Bone volume1.63.16.3-0.1-1.21.21.6-1.92.2-2.3-2.5
Breakpoint value in progressive ratio session0.61.01.21.11.1-1.1-1.11.0-1.00.90.9
Number of licking bursts0.61.73.9-2.0-1.61.61.3-1.20.9-0.8-0.6
Context. condit. distance diff. score0.20.20.5-0.7-0.60.60.4-0.40.1-0.1-0.1
Locomotion velocity, session 10.40.50.8-0.2-0.50.50.6-0.70.8-0.8-0.9
Locomotion distance, session 10.20.20.60.4-0.10.10.2-0.40.6-0.7-0.8
Locomotion velocity, session 20.20.31.31.20.6-0.6-0.40.2-0.10.1-0.1
Locomotion distance, session 21.21.74.52.11.5-1.5-1.21.1-0.90.90.6
Locomotion velocity, session 34.24.96.22.42.5-2.5-2.32.2-1.91.91.9
Locomotion distance, session 30.20.20.30.40.4-0.4-0.50.5-0.50.50.5
Stereotopy head waving bouts, day 33.94.66.82.62.5-2.5-2.22.1-1.71.61.6
Stereotopy head waving duration, day 31.92.43.92.01.9-1.9-1.61.5-1.01.00.9
Locomotion velocity, session 70.00.00.10.10.0-0.00.1-0.10.2-0.2-0.2
Locomotion distance, session 70.00.00.2-0.4-0.10.1-0.00.1-0.20.20.3
Stereotopy head waving bouts, day 70.30.30.91.00.7-0.7-0.50.4-0.10.0-0.0
Stereotopy head waving duration, day 70.20.21.01.00.6-0.6-0.40.2-0.00.0-0.2
Locomotion velocity, session 80.30.41.51.20.8-0.8-0.60.4-0.20.2-0.0
Locomotion distance, session 80.30.40.60.80.6-0.6-0.60.6-0.60.70.5
Degree of sensitization distance0.70.71.0-1.0-0.90.90.9-0.90.8-0.8-0.7
Degree of sensitization stereotypy0.30.30.7-0.3-0.40.40.5-0.60.7-0.7-0.8
Conditioned locomotion0.10.10.7-0.8-0.40.40.2-0.10.00.10.1
Cocaine response after cond. corrected0.91.33.2-1.8-1.11.11.0-1.01.1-0.9-0.9
Cocaine response after cond. not corrected0.91.33.1-1.8-1.11.11.0-0.91.1-0.9-0.9
Cocaine response before conditioning0.30.30.80.90.7-0.7-0.60.5-0.50.40.3
Saline control response0.10.10.3-0.5-0.50.50.3-0.20.00.1-0.0
Bone: connectivity density0.61.02.2-0.2-0.60.60.9-1.01.3-1.3-1.5
Bone: cortical apparent density1.01.62.2-1.4-1.51.51.3-1.31.1-1.0-1.1
Bone: cortical area2.23.64.6-1.2-1.71.71.9-2.02.0-2.1-2.1
Bone: cortical porosity0.20.20.4-0.1-0.40.40.5-0.60.6-0.5-0.7
Bone: cortical porosity0.80.91.4-0.5-0.90.91.0-1.11.1-1.0-1.2
Bone: cortical thickness2.33.84.5-1.6-2.12.12.1-2.11.9-1.7-2.0
Bone: cortical thickness0.30.30.7-0.8-0.80.80.6-0.50.3-0.2-0.3
Bone: cortical tissue density0.71.11.5-1.1-1.21.21.1-1.00.9-0.8-0.9
Condit. Reinf. active minus inactive responses1.01.21.81.31.4-1.4-1.11.1-0.70.70.7
Condit. Reinf. active-inactive response ratio0.10.10.30.20.6-0.6-0.30.30.2-0.1-0.1
Condit. Reinf. active responses1.41.83.21.81.5-1.5-1.31.2-1.11.11.0
Condit. Reinf. inactive responses1.11.42.41.51.0-1.0-1.01.0-1.31.31.2
Incentive salience index mean0.40.51.31.10.9-0.9-0.70.6-0.40.40.2
Condit. Reinf. lever presses0.10.10.50.70.2-0.20.1-0.20.3-0.3-0.6
Condit. Reinf. active minus inactive responses2.43.74.01.72.0-2.0-2.02.0-1.91.81.9
Condit. Reinf. active-inactive response ratio1.11.82.20.81.4-1.4-1.41.5-1.31.31.5
Condit. Reinf. active responses1.52.22.51.51.6-1.6-1.51.5-1.41.41.4
Condit. Reinf. inactive responses0.10.20.40.60.4-0.4-0.40.3-0.50.40.4
Condit. Reinf. lever presses3.24.65.22.02.1-2.1-2.22.2-2.32.22.3
Condit. Reinf. lever reinforcers received1.52.12.21.31.5-1.5-1.51.5-1.51.51.5
Conditioned reinforcement - actives0.00.10.1-0.3-0.30.30.3-0.30.3-0.1-0.3
Conditioned reinforcement - inactives0.10.30.8-0.9-0.60.60.5-0.50.3-0.2-0.3
Conditioned locomotion0.71.11.91.41.1-1.1-1.00.9-0.90.90.7
Patch foraging indifference point 0 sec2.77.58.0-2.7-2.82.82.8-2.82.7-2.6-2.7
Patch foraging indifference point AUC0.40.91.30.91.1-1.1-1.01.0-0.80.70.8
Delay disc. indifference point, 0s delay2.63.03.8-1.2-1.71.71.8-1.81.8-1.8-1.9
Delay disc. indifference point, 16s delay0.10.10.30.50.4-0.4-0.30.3-0.30.20.3
Delay disc. indifference point, 2s delay0.60.61.0-0.4-0.70.70.8-0.80.9-1.0-0.9
Delay disc. indifference point, 24s delay0.10.10.2-0.3-0.40.40.4-0.40.4-0.4-0.4
Delay disc. indifference point, 4s delay0.10.10.30.60.2-0.2-0.10.00.0-0.1-0.1
Delay disc. indifference point, 8s delay0.00.00.1-0.2-0.10.10.0-0.0-0.10.10.2
Indifference point function ln k0.10.20.3-0.4-0.40.40.5-0.50.5-0.4-0.5
Indifference point function log k0.10.20.3-0.4-0.40.40.5-0.50.5-0.4-0.5
Patch foraging total patch changes 0 sec2.36.77.1-2.6-2.72.72.6-2.62.6-2.5-2.6
Patch foraging total patch changes 12 sec1.21.62.7-1.6-1.41.41.3-1.21.0-1.0-0.9
Patch foraging total patch changes 18 sec0.00.10.1-0.2-0.20.20.2-0.20.3-0.3-0.3
Patch foraging total patch changes 24 sec0.30.91.3-0.8-0.90.90.9-0.91.0-1.1-0.9
Patch foraging total patch changes 6 sec1.93.23.6-1.9-1.91.91.8-1.81.7-1.6-1.6
Patch foraging time to switch 0 sec0.10.50.6-0.5-0.80.80.7-0.70.7-0.7-0.8
Patch foraging water rate 0 sec0.10.30.9-1.0-0.60.60.5-0.50.3-0.2-0.2
Patch foraging water rate 12 sec0.20.61.4-1.2-0.70.70.7-0.70.8-0.6-0.7
Patch foraging water rate 18 sec0.30.71.4-0.10.6-0.6-0.80.9-1.01.01.2
Patch foraging water rate 24 sec0.30.41.8-1.3-0.60.60.3-0.1-0.30.50.5
Patch foraging water rate 6 sec0.71.01.40.51.0-1.0-1.11.1-1.01.11.2
Seeking ratio, delayed vs. immediate footshock0.50.71.31.10.9-0.9-0.80.8-0.70.40.6
Distance traveled before self-admin0.71.51.91.41.3-1.3-1.21.2-1.11.01.0
Distance traveled after self-admin0.00.00.00.20.2-0.2-0.20.2-0.10.10.1
Extensor digitorum longus weight3.514.021.5-4.6-4.24.23.8-3.63.2-3.1-3.0
Bone: elastic displacement0.00.00.00.0-0.10.10.1-0.10.00.0-0.1
Bone: elastic work1.11.51.7-1.0-1.31.31.3-1.31.1-1.1-1.2
Bone: endosteal estimation0.92.23.1-1.3-1.41.41.5-1.51.5-1.8-1.5
Bone: endosteal perimeter0.10.30.50.60.2-0.20.1-0.20.7-0.7-0.7
Epididymis fat weight0.10.71.00.30.8-0.8-0.80.9-0.90.91.0
Delta time in closed arm before/after self-admin0.30.31.7-1.3-0.60.60.4-0.20.1-0.20.2
Delta time in open arm before/after self-admin0.40.40.6-0.8-0.70.70.7-0.70.6-0.5-0.6
Diff in mean of infusions in LGA sessions1.32.22.61.51.6-1.6-1.51.5-1.41.41.4
Delay discount exponential model param0.00.00.0-0.1-0.00.0-0.00.0-0.00.10.0
Extinction: sum of active levers before priming1.72.52.81.31.6-1.6-1.61.7-1.61.61.6
Active lever presses in extinction session 60.10.10.20.40.3-0.3-0.20.2-0.10.20.1
Bone: final force4.26.97.6-2.3-2.62.62.7-2.82.6-2.7-2.6
Bone: final moment4.26.77.5-2.2-2.62.62.7-2.72.6-2.6-2.6
Food consumed during 24 hour testing period0.10.30.5-0.5-0.70.70.6-0.50.2-0.2-0.2
Glucose1.21.82.1-1.5-1.31.31.3-1.31.4-1.4-1.3
Heart weight0.30.40.60.60.8-0.8-0.70.7-0.50.60.6
Delay discount hyperbolic model param0.10.20.30.20.4-0.4-0.40.4-0.40.50.4
Intermittent access intake day 1-15 change0.20.91.00.70.9-0.9-1.01.0-1.00.91.0
Intermittent access intake escalation0.20.81.00.70.9-0.9-1.01.0-1.01.01.0
Intermittent access intake escalation 20.50.91.00.91.0-1.0-1.01.0-0.90.80.9
Intermitt. access day 1 inactive lever presses0.21.92.80.61.2-1.2-1.41.5-1.61.61.7
Intermitt. access day 15 inactive lever presses0.31.62.21.11.2-1.2-1.21.2-1.31.51.3
Intermitt. access escalation Index0.10.30.4-0.1-0.50.50.6-0.60.6-0.6-0.7
Intermittent access day 1 total infusions0.10.20.3-0.6-0.40.40.4-0.40.3-0.3-0.3
Intermittent access day 15 total infusions0.00.00.0-0.2-0.20.20.2-0.20.2-0.1-0.2
Intermittent access terminal intake (last 3 days)0.00.10.20.0-0.20.20.3-0.30.4-0.3-0.4
Intermittent access total infusions0.30.30.4-0.5-0.50.50.6-0.60.6-0.4-0.6
Intermittent access day 1 locomotion0.00.10.2-0.20.1-0.1-0.20.2-0.30.40.4
Intermittent access day 15 total locomotion0.10.30.40.30.5-0.5-0.50.5-0.50.60.6
Intermittent access total locomotion0.10.10.20.20.4-0.4-0.40.4-0.40.40.4
Intermittent access standard deviation0.10.30.80.90.6-0.6-0.50.5-0.40.50.3
Left kidney weight0.00.10.30.20.2-0.2-0.30.4-0.50.40.6
Right kidney weight0.21.72.31.01.1-1.1-1.21.3-1.51.51.5
Cocaine induced anxiety0.20.61.91.40.9-0.9-0.80.7-0.50.30.3
Post-drug Anxiety0.20.20.60.80.2-0.20.0-0.20.4-0.7-0.6
Baseline Anxiety0.00.00.1-0.2-0.20.20.2-0.20.2-0.3-0.2
Tail length3.116.718.44.04.0-4.0-4.04.0-4.34.24.2
Length with tail2.19.310.82.82.9-2.9-3.03.0-3.33.33.3
Length without tail0.10.30.7-0.8-0.60.60.6-0.50.5-0.5-0.4
Times rat made contact with spout0.50.61.3-1.2-0.90.90.8-0.70.6-0.5-0.5
Lifetime Intake1.21.51.6-1.2-1.21.21.3-1.31.3-1.1-1.3
Liver weight, left0.20.30.5-0.7-0.70.70.7-0.60.4-0.3-0.4
Liver weight, right0.30.60.90.50.8-0.8-0.80.8-0.90.80.9
Locomotor activity2.43.76.62.62.0-2.0-1.91.8-1.71.71.5
Locomotor testing distance0.61.52.91.71.3-1.3-1.21.1-1.00.90.8
Locomotor testing rearing0.10.20.40.30.3-0.3-0.40.5-0.70.60.7
Locomotion in novel chamber0.10.10.1-0.3-0.40.40.3-0.30.3-0.3-0.2
Locomotion in novel chamber post-restriction1.75.16.82.62.5-2.5-2.32.2-2.01.72.0
Fecal boli incidents, locomotor time 10.10.20.7-0.8-0.50.50.4-0.40.4-0.4-0.3
Change in fecal boli incidents, locomotor task0.10.10.50.70.3-0.3-0.20.1-0.20.1-0.0
Time >=10cm from walls, locomotor time 10.91.21.6-0.7-1.01.01.1-1.21.2-1.2-1.2
Bouts of movement, locomotor time 10.60.81.00.90.9-0.9-0.90.9-0.91.00.9
Total resting periods, locomotor time 11.41.61.81.31.3-1.3-1.21.2-1.21.21.2
Rest time, locomotor task time 10.20.40.80.90.7-0.7-0.60.5-0.50.50.4
Distance moved, locomotor task time 10.61.62.0-1.0-1.31.31.3-1.31.3-1.3-1.4
Vertical activity count, locomotor time 10.21.41.9-1.4-1.31.31.2-1.11.1-1.0-1.0
Time >=10cm from walls, locomotor time 20.30.71.4-1.2-1.01.00.9-0.80.7-0.8-0.6
Bouts of movement, locomotor time 20.00.00.30.50.1-0.10.0-0.10.00.0-0.1
Total resting periods, locomotor time 20.00.10.20.5-0.00.00.1-0.20.2-0.1-0.3
Rest time, locomotor task time 20.00.00.10.30.0-0.00.1-0.10.2-0.2-0.3
Distance moved, locomotor task time 20.10.10.3-0.20.1-0.1-0.20.3-0.40.50.4
Vertical activity count, locomotor time 20.20.41.4-1.2-0.80.80.6-0.50.4-0.2-0.2
Light reinforcement 11.04.77.62.82.3-2.3-2.12.0-2.02.11.7
Light reinforcement 20.61.42.01.41.1-1.1-1.11.0-1.21.41.1
Bone: marrow area0.82.02.9-1.2-1.31.31.4-1.41.4-1.7-1.4
Bone: maximum diameter0.20.40.90.50.1-0.10.2-0.40.8-1.0-0.9
Bone: maximum force3.77.38.0-2.3-2.72.72.8-2.82.8-2.8-2.8
Bone: maximum moment3.87.27.8-2.3-2.72.72.8-2.82.7-2.8-2.7
Mean time between licks in bursts0.21.21.60.91.0-1.0-1.11.1-1.21.31.2
Mean num. licks in bursts0.20.41.01.00.8-0.8-0.70.6-0.40.50.3
Cd content in liver0.00.10.10.40.2-0.2-0.30.2-0.10.10.1
Co content in liver3.33.94.42.11.9-1.9-2.02.0-1.92.11.8
Cu content in liver1.01.21.6-0.8-1.11.11.1-1.11.0-1.3-1.1
Fe content in liver0.10.10.4-0.7-0.50.50.3-0.30.2-0.2-0.1
K content in liver0.30.30.80.90.5-0.5-0.50.5-0.50.40.4
Mg content in liver0.70.81.31.20.9-0.9-0.90.8-0.90.80.8
Mn content in liver0.30.31.61.30.6-0.6-0.40.2-0.0-0.2-0.3
Na content in liver0.50.61.4-0.3-0.40.40.6-0.60.9-1.2-1.0
Rb content in liver0.70.81.3-0.6-0.80.81.0-1.00.9-1.1-0.9
Se content in liver0.00.00.0-0.00.1-0.1-0.10.00.1-0.2-0.0
Sr content in liver0.30.30.60.40.4-0.4-0.50.5-0.50.80.6
Zn content in liver4.45.16.41.82.2-2.2-2.32.3-2.42.42.5
Bone: minimum diameter1.01.82.8-0.7-1.11.11.3-1.41.6-1.7-1.7
Time in familiar zone, hab. session 15.05.56.12.22.5-2.5-2.42.4-2.32.12.3
Time in novel zone, hab. session 14.45.05.4-1.9-2.32.32.3-2.32.2-2.1-2.3
Total zone transitions, hab. session 10.10.10.50.70.3-0.3-0.20.10.0-0.1-0.2
Total locomotion distance, hab. session 10.40.62.31.50.9-0.9-0.70.5-0.40.30.1
Locomotion velocity, hab. session 10.60.92.61.61.1-1.1-0.90.7-0.60.50.3
Time in familiar zone, hab. session 26.37.28.22.52.6-2.6-2.72.7-2.72.92.7
Time in novel zone, hab. session 27.78.410.1-2.6-2.82.82.9-2.93.0-3.2-3.0
Total zone transitions, hab. session 21.62.13.5-0.7-1.31.31.4-1.51.6-1.6-1.9
Total locomotion distance, hab. session 20.10.10.60.80.3-0.3-0.20.1-0.10.1-0.1
Locomotion velocity, hab. session 20.10.10.80.90.3-0.3-0.20.1-0.00.0-0.2
Novel to familiar place preference ratio3.54.54.9-1.8-2.12.12.2-2.22.2-2.2-2.2
Novelty place preference2.53.23.6-1.5-1.81.81.8-1.81.8-1.9-1.9
Time in novel zone, NPP test3.34.04.3-1.8-2.02.02.0-2.12.0-2.1-2.1
Total zone transitions, NPP test0.50.70.9-0.5-0.90.90.9-0.90.8-0.8-0.9
Total locomotion distance, NPP test0.20.20.40.0-0.50.50.5-0.60.5-0.5-0.7
Locomotion velocity, NPP test0.00.00.10.4-0.10.10.1-0.20.1-0.1-0.3
Intraocular pressure0.91.41.80.71.1-1.1-1.21.3-1.21.31.4
Delta distance traveled before/after self-admin0.30.40.6-0.8-0.70.70.6-0.60.5-0.6-0.5
Delta ambulatory time before/after self-admin0.40.70.8-0.8-0.90.90.9-0.90.9-0.9-0.8
Parametrial fat weight0.51.21.4-1.1-1.11.11.1-1.11.0-1.2-1.0
Pavlov. Cond. lever latency0.40.51.3-0.20.2-0.2-0.50.6-1.00.91.1
Pavlov. Cond. magazine entry latency1.21.62.11.51.3-1.3-1.31.2-1.11.21.0
Pavlov. Cond. change in total contacts0.30.30.4-0.5-0.60.60.6-0.60.6-0.5-0.6
Pavlov. Cond. index score0.10.20.70.80.5-0.5-0.30.3-0.10.2-0.0
Pavlov. Cond. latency score0.10.10.70.80.4-0.4-0.20.10.1-0.1-0.3
Pavlov. Cond. lever contacts0.50.61.30.1-0.40.40.6-0.71.0-0.9-1.2
Pavlov. Cond. magazine entry number0.50.70.9-0.9-0.90.90.9-0.80.7-0.8-0.7
Pavlov. Cond. intertrial magazine entries0.30.40.70.20.4-0.4-0.50.6-0.80.70.9
Pavlov. Cond. lever-magazine prob. diff.0.20.20.70.90.6-0.6-0.40.3-0.20.30.1
Pavlov. Cond. response bias0.40.40.70.90.8-0.8-0.70.6-0.50.50.5
Pavlov. Cond. lever latency2.02.83.4-1.7-1.51.51.6-1.61.8-1.7-1.8
Pavlov. Cond. magazine entry latency2.23.13.51.81.6-1.6-1.71.7-1.91.81.8
Pavlov. Cond. change in total contacts0.61.51.91.11.1-1.1-1.21.2-1.41.41.4
Pavlov. Cond. index score2.03.23.81.71.6-1.6-1.71.8-1.91.81.9
Pavlov. Cond. latency score2.03.23.61.81.7-1.7-1.71.7-1.91.81.8
Pavlov. Cond. lever contacts1.92.93.51.61.5-1.5-1.71.7-1.91.71.9
Pavlov. Cond. magazine entry number2.43.13.6-1.8-1.61.61.7-1.71.9-1.8-1.8
Pavlov. Cond. intertrial magazine entries0.51.01.5-1.2-1.01.01.0-0.91.0-1.1-0.9
Pavlov. Cond. lever-magazine prob. diff.2.13.23.81.81.6-1.6-1.71.7-1.91.81.9
Pavlov. Cond. response bias3.24.45.41.91.9-1.9-2.12.1-2.32.22.3
Time in closed arm before self-admin0.20.40.6-0.2-0.60.60.6-0.70.7-0.8-0.8
Time in closed arm after self-admin0.60.60.9-0.8-0.90.90.8-0.70.7-0.9-0.6
Time in open arm before self-admin0.00.00.0-0.1-0.10.10.1-0.10.10.1-0.1
Time in open arm after self-admin0.80.91.6-1.3-1.11.11.0-1.00.9-0.6-0.8
Bone: periosteal estimation1.94.55.9-1.5-2.02.02.2-2.22.2-2.4-2.3
Bone: periosteal perimeter0.51.01.9-0.1-0.70.70.9-1.01.2-1.3-1.4
Bone: post-yield work0.40.71.0-1.0-0.90.90.8-0.80.7-0.9-0.6
Progressive ratio test 1 active lever presses0.30.40.7-0.8-0.70.70.7-0.70.6-0.5-0.6
Progressive ratio test 1 breakpoint0.30.40.7-0.8-0.70.70.7-0.60.6-0.5-0.6
Progressive ratio test 1 inactive lever presses0.00.10.10.30.3-0.3-0.30.3-0.30.30.2
Progressive ratio test 2 active lever presses0.00.00.00.10.1-0.1-0.10.0-0.00.20.0
Progressive ratio test 2 breakpoint0.00.00.10.20.2-0.2-0.20.2-0.10.30.1
Progressive ratio test 2 inactive lever presses0.10.40.7-0.4-0.60.60.7-0.70.7-0.5-0.8
Incentive Sensitization - Responses0.20.50.60.70.8-0.8-0.70.7-0.70.80.7
Incentive Sensitization - Breakpoint0.30.60.70.80.8-0.8-0.80.7-0.70.80.7
Sum of active levers in priming session hrs 5-60.10.10.20.30.4-0.4-0.40.4-0.30.20.3
Progressive ratio0.31.01.7-1.3-1.21.21.1-1.00.8-0.6-0.7
Food seeking constrained by brief footshock2.12.73.41.71.8-1.8-1.71.6-1.41.41.4
Seeking ratio, punishment vs. effort1.53.44.52.12.1-2.1-1.91.9-1.61.41.5
Retroperitoneal fat weight1.25.210.0-3.2-2.62.62.2-2.01.8-1.9-1.5
Reaction time number correct0.10.31.2-1.1-0.70.70.5-0.40.3-0.3-0.1
Reaction time mean minus median0.21.52.11.41.3-1.3-1.31.2-1.21.01.1
Reaction time mean minus median AUC0.10.72.21.50.9-0.9-0.80.7-0.60.40.5
Reaction time num false alarms0.30.50.8-0.8-0.90.90.8-0.70.5-0.3-0.5
Reaction time num false alarms AUC0.20.40.6-0.7-0.80.80.7-0.60.4-0.2-0.4
Reaction time trials correct on left0.10.31.2-1.1-0.70.70.5-0.40.3-0.3-0.1
Reaction time trials on left0.10.31.1-1.1-0.70.70.5-0.40.3-0.4-0.1
Reaction time mean0.30.71.71.31.0-1.0-0.90.7-0.50.40.4
Reaction time mean AUC0.10.20.60.80.5-0.5-0.40.3-0.0-0.1-0.1
Median of all reaction times0.20.30.80.90.7-0.7-0.50.4-0.20.10.1
Reaction time omissions0.10.10.3-0.0-0.30.30.3-0.30.4-0.6-0.5
Reaction time false alarm rate0.10.20.3-0.2-0.50.50.5-0.50.4-0.2-0.5
Reaction time premature initiation rate2.03.13.81.61.8-1.8-1.81.8-1.82.01.8
Reaction time premature initiations0.72.23.00.91.4-1.4-1.51.6-1.61.71.7
Std. dev. reaction times0.10.51.11.10.8-0.8-0.70.6-0.50.30.4
Reaction time trials completed0.10.31.1-1.1-0.70.70.5-0.40.3-0.4-0.1
Reaction time trials AUC0.10.31.3-1.1-0.70.70.5-0.40.2-0.2-0.1
Run reversals in cocaine runway, females1.41.53.01.71.4-1.4-1.31.1-0.90.90.8
Run reversals in cocaine runway, males0.91.02.21.51.3-1.3-1.00.9-0.60.40.5
Latency to leave start box in cocaine runway0.30.40.6-0.1-0.80.80.6-0.70.6-0.6-0.8
Latency to leave start box in cocaine runway, F0.81.01.6-0.2-0.90.90.9-1.01.1-1.2-1.3
Latency to leave start box in cocaine runway, M0.10.10.40.1-0.00.0-0.30.3-0.50.70.5
Std. dev. time between licks in bursts0.20.30.60.80.5-0.5-0.50.5-0.60.50.5
Total sessions with >9 infusions1.21.51.6-1.1-1.21.21.2-1.21.2-1.2-1.2
Short access day 1 total inactive lever presses0.40.70.90.50.9-0.9-0.80.9-0.90.90.9
Short access day 10 total inactive lever presses0.10.91.60.10.8-0.8-0.91.0-1.11.11.3
Short access day 1 total infusions0.71.41.5-1.1-1.21.21.2-1.21.2-1.1-1.2
Short access day 10 total infusions0.20.30.5-0.7-0.60.60.6-0.60.5-0.5-0.5
Short access total infusions1.42.02.3-1.3-1.51.51.5-1.51.4-1.3-1.4
Short access day 1 locomotion0.20.30.50.30.6-0.6-0.60.6-0.70.60.7
Short access day 10 total locomotion0.83.23.81.31.8-1.8-1.91.9-1.81.81.9
Short access total locomotion0.20.30.40.30.6-0.6-0.60.6-0.60.60.6
One hour access (0.3 mA shock)0.10.10.2-0.5-0.30.30.3-0.30.4-0.3-0.4
Compulsive drug intake0.00.00.00.20.1-0.1-0.00.00.0-0.1-0.0
One hour access (shock baseline)0.00.00.10.00.2-0.2-0.20.2-0.10.30.1
Social response proportion0.91.11.61.31.1-1.1-1.01.0-1.11.00.9
Social responses7.39.614.43.83.4-3.4-3.12.9-2.82.72.5
Social time0.50.81.4-1.2-1.01.00.9-0.90.8-0.7-0.7
Soleus weight5.616.518.4-4.2-4.34.34.1-4.04.0-3.7-3.9
Bone: stiffness4.68.48.9-2.8-2.92.93.0-3.02.9-2.9-2.8
Tibialis anterior weight1.34.65.0-2.2-2.12.12.1-2.12.2-2.2-2.1
Time to tail flick, vehicle, before self-admin0.30.41.21.10.7-0.7-0.60.5-0.40.00.3
Time to tail flick, vehicle, after self-admin0.61.31.70.81.1-1.1-1.21.2-1.21.31.3
Time to tail flick, test, before self-admin0.10.10.60.70.3-0.3-0.20.1-0.10.1-0.0
Time to tail flick, test, after self-admin0.10.10.3-0.1-0.30.30.3-0.40.5-0.5-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.7-0.9-0.40.40.2-0.10.10.20.1
Delta time to tail flick, test, before/after SA0.10.20.3-0.00.3-0.3-0.40.5-0.50.40.6
Tibia length1.33.54.01.81.8-1.8-1.81.9-2.01.91.9
Ambulatory time before self-admin0.10.40.50.70.7-0.7-0.70.6-0.60.60.5
Ambulatory time after self-admin0.00.00.00.10.0-0.0-0.0-0.00.1-0.2-0.1
Bone: tissue strength6.97.27.5-2.6-2.72.72.7-2.72.7-2.7-2.7
Total heroin consumption1.72.03.11.71.6-1.6-1.41.4-1.21.21.1
Bone: trabecular number0.10.20.60.80.3-0.3-0.0-0.10.4-0.5-0.6
Bone: trabecular spacing0.40.61.3-0.40.3-0.3-0.60.7-0.91.11.1
Bone: trabecular thickness1.72.44.1-0.3-1.31.31.6-1.71.7-1.8-2.0
Bone: trabecular tissue density3.45.98.4-2.9-2.52.52.4-2.42.3-2.3-2.1
Water consumed over 24 hours0.61.21.4-0.8-1.21.21.2-1.21.1-1.1-1.2
Number of responses in last shaping day1.82.42.61.41.5-1.5-1.61.6-1.61.61.6