LOC134479730

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC134479730 0.14 0.09 1.6e-03 0.09 0.1 0.16 0.11 4.5e-03 1.7e-03 1.3e-04 1.2e-03
2 pVTA gene expression LOC134479730 0.2 0.08 0.0e+00 0.29 0.28 0.29 0.29 1.9e-23 3.7e-23 2.1e-23 1.8e-23
3 Brain gene expression LOC134479730 0.11 0.05 1.4e-13 0.14 0.13 0.14 0.14 8.8e-13 7.7e-12 1.1e-12 1.5e-12
4 LHb gene expression LOC134479730 0.17 0.11 1.4e-03 0.07 0.08 0.06 0.06 9.8e-03 6.5e-03 1.9e-02 1.4e-02
5 PL gene expression LOC134479730 0.03 0.02 2.6e-04 0.03 0.03 0.02 0.02 4.7e-04 4.8e-04 1.9e-03 1.3e-03
6 NAcc gene expression LOC134479730 0.04 0.02 3.7e-10 0.06 0.07 0.06 0.06 7.0e-09 7.2e-11 2.4e-09 3.3e-09
7 BLA gene expression LOC134479730 0.09 0.08 2.3e-03 0.01 0.03 0.03 0.02 7.1e-02 1.5e-02 8.3e-03 2.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.30.51.10.9-0.40.5-1.10.4-0.80.7
Area under the delay curve0.10.10.2-0.40.3-0.20.5-0.50.3-0.2
BMI with tail2.69.210.73.1-3.03.1-3.13.1-3.32.4
BMI without tail0.31.42.01.4-1.21.0-1.41.0-1.40.6
Body weight2.410.313.72.8-3.03.3-3.73.1-3.72.8
Weight adjusted by age0.10.20.60.20.4-0.0-0.7-0.2-0.5-0.7
Bone surface0.10.30.70.8-0.40.4-0.60.4-0.50.4
Bone volume0.20.30.80.9-0.40.5-0.70.3-0.60.4
Breakpoint value in progressive ratio session0.40.71.2-0.50.9-0.81.1-0.61.0-0.9
Number of licking bursts0.20.71.6-0.60.6-0.80.7-1.30.8-0.7
Context. condit. distance diff. score0.00.00.1-0.3-0.10.4-0.10.2-0.10.1
Locomotion velocity, session 10.10.10.4-0.30.2-0.30.1-0.70.3-0.4
Locomotion distance, session 10.81.02.41.5-1.20.8-0.91.0-0.70.5
Locomotion velocity, session 20.20.20.70.7-0.0-0.1-0.80.1-0.50.1
Locomotion distance, session 21.21.63.31.8-1.31.2-1.11.2-1.01.2
Locomotion velocity, session 30.10.10.30.5-0.40.20.20.20.2-0.1
Locomotion distance, session 30.80.91.41.1-1.21.1-0.21.0-0.51.0
Stereotopy head waving bouts, day 30.10.10.1-0.10.3-0.30.4-0.20.2-0.0
Stereotopy head waving duration, day 31.72.12.7-1.61.5-1.51.3-1.31.3-1.4
Locomotion velocity, session 70.30.30.7-0.80.3-0.30.9-0.40.7-0.4
Locomotion distance, session 70.60.72.2-1.00.4-0.21.5-0.61.1-0.2
Stereotopy head waving bouts, day 70.00.00.1-0.10.2-0.4-0.1-0.1-0.0-0.4
Stereotopy head waving duration, day 70.10.10.3-0.20.3-0.6-0.1-0.20.1-0.5
Locomotion velocity, session 80.70.91.41.2-1.00.8-1.10.9-0.90.4
Locomotion distance, session 80.60.91.31.1-1.11.2-0.71.1-0.60.8
Degree of sensitization distance1.41.52.6-1.61.3-1.11.2-1.31.2-0.7
Degree of sensitization stereotypy0.30.41.0-0.60.6-0.80.1-0.40.4-1.0
Conditioned locomotion0.30.41.2-0.40.4-0.41.10.11.0-0.2
Cocaine response after cond. corrected0.20.20.40.6-0.30.4-0.60.4-0.60.4
Cocaine response after cond. not corrected0.30.40.60.7-0.50.6-0.70.7-0.80.6
Cocaine response before conditioning0.70.91.20.6-1.11.0-0.81.1-0.91.0
Saline control response0.20.20.60.8-0.60.3-0.10.2-0.20.7
Bone: connectivity density0.61.01.71.3-0.70.8-1.20.5-1.01.1
Bone: cortical apparent density7.712.117.0-4.13.6-3.43.2-3.23.4-3.2
Bone: cortical area0.10.10.4-0.30.10.10.60.10.4-0.4
Bone: cortical porosity2.32.53.7-1.91.7-1.51.7-1.01.5-1.7
Bone: cortical porosity2.02.22.8-1.61.5-1.41.7-1.01.4-1.5
Bone: cortical thickness0.20.40.6-0.70.5-0.30.8-0.30.7-0.7
Bone: cortical thickness0.10.10.2-0.30.10.00.5-0.10.30.2
Bone: cortical tissue density7.512.016.6-4.13.6-3.43.2-3.33.4-3.2
Condit. Reinf. active minus inactive responses1.61.82.71.6-1.61.4-1.10.8-1.21.6
Condit. Reinf. active-inactive response ratio0.90.91.81.3-1.00.9-0.90.3-0.91.1
Condit. Reinf. active responses2.63.34.82.0-2.22.0-1.31.5-1.62.0
Condit. Reinf. inactive responses1.01.32.11.0-1.41.3-0.71.4-1.01.1
Incentive salience index mean2.63.34.72.2-2.21.8-1.41.5-1.61.9
Condit. Reinf. lever presses2.53.75.32.3-2.21.8-1.41.9-1.71.9
Condit. Reinf. active minus inactive responses0.10.21.1-0.60.1-0.2-0.10.2-0.0-1.0
Condit. Reinf. active-inactive response ratio1.32.04.4-1.91.2-1.21.1-1.01.1-2.1
Condit. Reinf. active responses0.30.51.00.5-0.90.6-0.71.0-0.70.0
Condit. Reinf. inactive responses1.11.72.71.6-1.51.2-1.01.2-1.11.4
Condit. Reinf. lever presses0.50.71.00.8-1.00.8-0.90.9-0.90.3
Condit. Reinf. lever reinforcers received0.20.30.70.3-0.80.5-0.50.9-0.6-0.2
Conditioned reinforcement - actives0.10.31.01.0-0.60.2-0.50.6-0.40.1
Conditioned reinforcement - inactives0.10.41.0-0.40.5-0.51.0-0.50.8-0.2
Conditioned locomotion0.50.71.11.0-0.60.6-0.90.8-0.80.9
Patch foraging indifference point 0 sec1.64.47.22.7-2.01.9-2.12.1-1.91.9
Patch foraging indifference point AUC1.12.64.11.7-1.81.8-1.11.4-1.32.0
Delay disc. indifference point, 0s delay0.10.10.40.50.0-0.3-0.60.0-0.3-0.1
Delay disc. indifference point, 16s delay0.81.11.9-0.80.9-1.01.3-1.41.1-0.7
Delay disc. indifference point, 2s delay0.20.20.8-0.9-0.30.5-0.00.2-0.3-0.2
Delay disc. indifference point, 24s delay0.00.10.2-0.10.10.10.5-0.30.30.2
Delay disc. indifference point, 4s delay0.20.20.40.1-0.10.5-0.40.6-0.50.6
Delay disc. indifference point, 8s delay0.00.10.20.2-0.30.20.2-0.1-0.00.4
Indifference point function ln k0.00.10.50.10.4-0.2-0.70.0-0.3-0.2
Indifference point function log k0.00.10.50.10.4-0.2-0.70.0-0.3-0.2
Patch foraging total patch changes 0 sec1.64.77.92.8-2.12.0-2.12.3-1.91.9
Patch foraging total patch changes 12 sec0.30.40.70.7-0.80.7-0.20.7-0.30.5
Patch foraging total patch changes 18 sec2.04.66.02.3-2.42.5-1.22.3-1.62.5
Patch foraging total patch changes 24 sec0.31.11.81.3-1.01.1-0.91.1-0.81.1
Patch foraging total patch changes 6 sec2.34.06.62.6-2.11.9-1.82.2-1.61.7
Patch foraging time to switch 0 sec1.14.47.2-2.71.8-2.11.8-2.11.8-2.2
Patch foraging water rate 0 sec1.97.010.63.3-2.22.6-2.82.9-2.52.2
Patch foraging water rate 12 sec0.51.83.81.2-0.81.4-1.62.0-1.30.7
Patch foraging water rate 18 sec0.71.62.71.4-0.91.2-1.61.6-1.30.6
Patch foraging water rate 24 sec0.40.61.60.9-0.20.5-1.20.9-0.80.4
Patch foraging water rate 6 sec1.62.44.71.4-1.21.7-1.82.2-1.50.7
Seeking ratio, delayed vs. immediate footshock0.20.20.50.3-0.60.4-0.50.1-0.50.7
Distance traveled before self-admin0.00.00.10.1-0.1-0.1-0.2-0.4-0.20.1
Distance traveled after self-admin0.20.41.21.1-0.30.3-0.80.5-0.50.1
Extensor digitorum longus weight7.931.636.16.0-5.85.8-5.65.4-5.75.1
Bone: elastic displacement0.00.00.1-0.30.3-0.20.1-0.10.1-0.3
Bone: elastic work0.40.60.8-0.90.9-0.70.7-0.50.6-0.9
Bone: endosteal estimation0.30.61.00.9-1.01.0-0.30.9-0.60.6
Bone: endosteal perimeter0.20.40.70.8-0.80.8-0.10.6-0.40.6
Epididymis fat weight0.00.10.20.1-0.10.50.00.3-0.10.2
Delta time in closed arm before/after self-admin0.30.20.4-0.40.7-0.30.6-0.40.6-0.4
Delta time in open arm before/after self-admin0.10.20.4-0.20.4-0.5-0.1-0.60.1-0.5
Diff in mean of infusions in LGA sessions0.10.20.70.20.10.2-0.80.5-0.6-0.1
Delay discount exponential model param0.10.10.20.4-0.20.1-0.50.4-0.30.1
Extinction: sum of active levers before priming0.00.10.3-0.0-0.30.20.10.1-0.10.5
Active lever presses in extinction session 60.40.40.7-0.70.4-0.50.8-0.00.8-0.7
Bone: final force0.30.40.70.5-0.70.8-0.50.8-0.60.2
Bone: final moment0.10.10.30.2-0.30.4-0.30.6-0.4-0.0
Food consumed during 24 hour testing period0.10.10.40.00.4-0.60.2-0.20.5-0.2
Glucose0.10.10.4-0.20.1-0.10.7-0.10.50.4
Heart weight0.40.61.6-1.31.0-0.60.5-0.70.5-0.4
Delay discount hyperbolic model param0.00.00.20.4-0.1-0.1-0.30.2-0.1-0.0
Intermittent access intake day 1-15 change0.42.12.9-1.51.4-1.71.3-1.31.5-1.3
Intermittent access intake escalation0.31.92.5-1.51.3-1.61.4-1.21.5-1.2
Intermittent access intake escalation 20.50.91.4-1.00.8-1.11.2-0.81.1-0.7
Intermitt. access day 1 inactive lever presses0.00.10.20.20.1-0.10.40.10.4-0.4
Intermitt. access day 15 inactive lever presses0.00.10.20.2-0.1-0.40.2-0.40.1-0.4
Intermitt. access escalation Index0.41.21.81.3-1.00.9-1.30.6-1.31.1
Intermittent access day 1 total infusions0.30.81.2-0.41.0-1.10.5-0.91.0-1.0
Intermittent access day 15 total infusions0.92.33.5-1.11.6-1.91.2-1.51.7-1.6
Intermittent access terminal intake (last 3 days)1.62.83.7-1.21.6-1.91.6-1.81.9-1.6
Intermittent access total infusions1.72.02.5-1.11.4-1.61.1-1.61.5-1.4
Intermittent access day 1 locomotion0.00.00.20.20.2-0.3-0.4-0.0-0.0-0.2
Intermittent access day 15 total locomotion0.10.41.0-0.40.8-0.9-0.1-0.40.5-1.0
Intermittent access total locomotion0.10.10.1-0.20.4-0.2-0.30.20.2-0.3
Intermittent access standard deviation0.00.20.60.2-0.2-0.70.5-0.80.4-0.0
Left kidney weight0.32.55.91.3-1.31.3-2.41.4-2.20.7
Right kidney weight0.32.25.01.2-1.11.1-2.21.3-2.10.9
Cocaine induced anxiety0.41.02.0-0.70.9-1.10.9-1.41.1-0.9
Post-drug Anxiety2.73.14.0-2.01.7-1.61.8-1.81.8-1.6
Baseline Anxiety0.30.51.7-1.30.9-0.40.6-0.10.5-0.6
Tail length0.10.71.5-1.20.8-0.70.6-0.90.6-0.7
Length with tail0.10.61.3-0.1-0.40.7-1.20.6-1.10.7
Length without tail2.010.412.03.2-2.93.3-3.53.4-3.33.0
Times rat made contact with spout5.15.97.5-2.72.6-2.52.3-2.32.4-2.1
Lifetime Intake1.21.52.0-0.91.3-1.41.1-1.41.4-1.1
Liver weight, left0.81.42.81.3-1.10.8-1.71.2-1.40.7
Liver weight, right0.40.81.50.6-0.60.8-1.21.0-1.10.4
Locomotor activity1.52.33.31.5-1.61.8-1.31.8-1.41.2
Locomotor testing distance0.51.31.71.0-1.31.3-1.01.2-1.10.9
Locomotor testing rearing0.10.20.7-0.3-0.50.80.10.8-0.2-0.2
Locomotion in novel chamber0.20.30.70.5-0.40.4-0.40.6-0.40.8
Locomotion in novel chamber post-restriction0.10.31.1-0.30.2-0.31.1-0.60.8-0.3
Fecal boli incidents, locomotor time 10.00.10.20.20.2-0.40.3-0.40.4-0.3
Change in fecal boli incidents, locomotor task0.40.40.9-1.00.9-0.20.5-0.20.7-0.8
Time >=10cm from walls, locomotor time 10.10.21.01.00.2-0.0-0.3-0.1-0.2-0.0
Bouts of movement, locomotor time 12.53.25.5-1.71.7-1.91.7-2.41.6-1.5
Total resting periods, locomotor time 11.61.93.9-1.41.2-1.31.3-2.01.2-1.0
Rest time, locomotor task time 11.11.72.8-1.51.0-0.81.7-1.61.4-0.7
Distance moved, locomotor task time 10.10.40.9-0.10.6-1.0-0.40.20.1-0.9
Vertical activity count, locomotor time 10.10.61.40.8-0.50.3-1.20.9-0.90.1
Time >=10cm from walls, locomotor time 20.41.12.1-0.31.4-0.91.0-1.40.8-1.0
Bouts of movement, locomotor time 20.00.10.4-0.20.1-0.30.3-0.70.1-0.2
Total resting periods, locomotor time 20.10.20.5-0.50.3-0.40.4-0.70.2-0.5
Rest time, locomotor task time 20.30.50.8-0.90.5-0.30.8-0.70.8-0.5
Distance moved, locomotor task time 20.10.10.30.10.4-0.5-0.4-0.1-0.30.1
Vertical activity count, locomotor time 20.40.91.81.3-0.70.4-1.20.5-1.10.8
Light reinforcement 10.10.51.41.2-0.90.5-0.50.4-0.40.4
Light reinforcement 20.00.10.30.20.1-0.60.2-0.30.4-0.1
Bone: marrow area0.30.81.11.1-1.11.0-0.41.0-0.60.7
Bone: maximum diameter0.10.20.7-0.0-0.20.30.90.20.5-0.1
Bone: maximum force0.30.61.20.8-0.80.9-0.61.1-0.70.4
Bone: maximum moment0.10.20.70.5-0.50.5-0.30.8-0.40.1
Mean time between licks in bursts0.21.32.4-1.50.9-0.91.4-0.61.1-1.2
Mean num. licks in bursts0.30.81.6-1.21.2-0.90.9-0.40.8-0.7
Cd content in liver0.50.50.70.8-0.80.5-0.70.8-0.80.8
Co content in liver0.00.10.10.10.1-0.40.3-0.30.10.0
Cu content in liver0.20.20.50.60.1-0.2-0.70.1-0.50.4
Fe content in liver0.20.20.40.4-0.40.3-0.70.4-0.60.0
K content in liver0.20.20.70.4-0.10.1-0.80.2-0.50.1
Mg content in liver0.60.71.3-0.81.2-0.90.3-0.90.6-0.7
Mn content in liver0.30.30.7-0.70.8-0.80.1-0.40.3-0.4
Na content in liver0.80.91.81.3-0.90.9-1.20.7-1.00.5
Rb content in liver0.40.41.60.7-0.30.5-0.50.2-0.41.3
Se content in liver0.00.00.1-0.20.2-0.3-0.30.1-0.3-0.0
Sr content in liver0.40.40.80.9-0.70.5-0.40.3-0.50.8
Zn content in liver1.11.32.41.5-0.90.8-1.21.1-1.11.3
Bone: minimum diameter0.50.92.3-1.00.7-0.41.5-0.51.2-0.8
Time in familiar zone, hab. session 10.20.20.30.6-0.40.4-0.20.4-0.20.6
Time in novel zone, hab. session 12.42.73.4-1.81.8-1.71.3-1.71.5-1.6
Total zone transitions, hab. session 11.72.42.91.6-1.41.6-1.71.5-1.61.5
Total locomotion distance, hab. session 12.13.03.61.7-1.71.9-1.91.5-1.71.5
Locomotion velocity, hab. session 11.52.13.11.3-1.51.8-1.51.3-1.41.2
Time in familiar zone, hab. session 21.41.62.2-1.51.1-1.11.4-1.21.3-1.2
Time in novel zone, hab. session 20.91.01.71.3-0.91.0-1.00.8-0.91.1
Total zone transitions, hab. session 22.12.63.91.9-1.71.6-1.22.0-1.31.5
Total locomotion distance, hab. session 21.01.31.91.2-1.41.4-0.81.3-0.91.0
Locomotion velocity, hab. session 21.01.31.81.2-1.31.3-0.91.2-0.91.0
Novel to familiar place preference ratio0.00.10.1-0.30.4-0.1-0.4-0.2-0.1-0.1
Novelty place preference0.20.30.6-0.60.8-0.6-0.1-0.60.3-0.5
Time in novel zone, NPP test0.20.30.6-0.60.8-0.6-0.1-0.60.3-0.5
Total zone transitions, NPP test2.43.55.22.3-2.12.1-1.32.1-1.51.6
Total locomotion distance, NPP test2.02.84.02.0-1.92.0-1.21.6-1.41.4
Locomotion velocity, NPP test2.33.34.72.1-2.12.2-1.21.8-1.51.6
Intraocular pressure0.10.10.6-0.40.20.20.30.10.00.8
Delta distance traveled before/after self-admin0.20.20.70.80.10.40.00.80.1-0.1
Delta ambulatory time before/after self-admin0.20.40.91.0-0.10.7-0.21.0-0.10.4
Parametrial fat weight0.00.10.4-0.70.00.3-0.1-0.2-0.40.2
Pavlov. Cond. lever latency1.01.32.3-1.51.5-1.10.3-1.20.7-1.2
Pavlov. Cond. magazine entry latency0.10.10.50.7-0.50.2-0.10.3-0.20.2
Pavlov. Cond. change in total contacts1.21.23.01.7-1.30.9-0.41.1-0.61.1
Pavlov. Cond. index score0.30.30.90.9-0.80.50.10.6-0.20.5
Pavlov. Cond. latency score0.40.61.31.1-1.00.60.00.7-0.30.7
Pavlov. Cond. lever contacts1.31.62.91.7-1.61.2-0.51.3-0.91.3
Pavlov. Cond. magazine entry number0.10.10.3-0.50.4-0.2-0.2-0.2-0.0-0.1
Pavlov. Cond. intertrial magazine entries1.92.33.01.4-1.71.5-1.61.3-1.71.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.9-0.80.50.10.7-0.20.4
Pavlov. Cond. response bias0.20.30.60.8-0.70.50.00.5-0.20.6
Pavlov. Cond. lever latency0.20.20.5-0.30.7-0.50.4-0.40.40.4
Pavlov. Cond. magazine entry latency0.20.30.60.1-0.70.8-0.40.6-0.60.1
Pavlov. Cond. change in total contacts0.41.11.40.7-1.21.1-1.11.2-1.20.4
Pavlov. Cond. index score0.40.61.00.6-1.01.0-0.60.9-0.80.1
Pavlov. Cond. latency score0.50.81.30.7-1.21.1-0.81.1-1.00.3
Pavlov. Cond. lever contacts0.20.30.60.4-0.80.5-0.40.5-0.5-0.4
Pavlov. Cond. magazine entry number0.81.11.5-0.81.2-1.20.9-1.21.1-0.5
Pavlov. Cond. intertrial magazine entries0.30.71.0-0.80.8-0.80.9-1.00.9-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.81.40.7-1.21.1-0.81.0-1.00.2
Pavlov. Cond. response bias0.20.30.70.3-0.80.7-0.30.5-0.5-0.3
Time in closed arm before self-admin0.30.61.01.0-0.70.6-0.81.0-0.60.5
Time in closed arm after self-admin0.20.20.50.00.6-0.70.1-0.10.5-0.5
Time in open arm before self-admin0.60.81.6-0.3-0.61.3-0.70.9-0.91.0
Time in open arm after self-admin0.40.40.60.4-0.50.8-0.70.5-0.70.6
Bone: periosteal estimation0.00.10.20.1-0.30.50.50.30.2-0.0
Bone: periosteal perimeter0.10.20.40.3-0.40.60.50.40.10.3
Bone: post-yield work3.15.47.52.7-2.62.3-2.02.2-2.12.3
Progressive ratio test 1 active lever presses0.40.71.4-0.51.0-1.10.2-0.70.8-1.2
Progressive ratio test 1 breakpoint0.40.71.3-0.50.9-1.10.2-0.70.8-1.1
Progressive ratio test 1 inactive lever presses0.00.00.10.00.1-0.1-0.30.1-0.1-0.2
Progressive ratio test 2 active lever presses0.20.20.5-0.10.5-0.70.0-0.50.4-0.6
Progressive ratio test 2 breakpoint0.10.20.4-0.10.4-0.70.0-0.40.4-0.5
Progressive ratio test 2 inactive lever presses0.00.10.30.40.2-0.60.0-0.40.3-0.2
Incentive Sensitization - Responses0.00.00.1-0.2-0.1-0.1-0.0-0.3-0.10.2
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.1-0.1-0.0-0.3-0.10.2
Sum of active levers in priming session hrs 5-60.10.10.2-0.2-0.00.10.40.30.20.1
Progressive ratio0.20.62.0-1.40.9-0.40.6-0.30.7-0.6
Food seeking constrained by brief footshock1.72.24.12.0-1.71.5-0.81.6-1.01.4
Seeking ratio, punishment vs. effort1.02.15.82.4-1.81.0-1.11.1-1.21.1
Retroperitoneal fat weight0.10.40.90.0-0.50.7-0.90.6-0.90.1
Reaction time number correct0.00.10.30.50.00.2-0.60.2-0.30.2
Reaction time mean minus median0.00.00.1-0.3-0.1-0.00.3-0.10.10.1
Reaction time mean minus median AUC0.10.51.2-1.10.6-0.60.7-0.70.5-0.7
Reaction time num false alarms1.73.05.1-2.01.4-1.22.2-1.41.9-1.5
Reaction time num false alarms AUC0.92.14.2-1.71.0-0.92.1-1.31.6-1.2
Reaction time trials correct on left0.00.10.30.50.00.2-0.60.2-0.30.2
Reaction time trials on left0.00.10.30.50.00.2-0.60.1-0.30.2
Reaction time mean0.10.20.8-0.90.10.00.8-0.30.3-0.3
Reaction time mean AUC0.20.51.5-1.20.3-0.11.0-0.50.5-0.6
Median of all reaction times0.30.51.3-1.20.3-0.11.1-0.50.5-0.6
Reaction time omissions0.30.51.3-1.00.3-0.31.1-0.60.6-0.4
Reaction time false alarm rate1.31.73.8-1.60.8-0.82.0-1.01.5-1.1
Reaction time premature initiation rate1.52.33.81.2-1.71.6-1.11.2-1.62.0
Reaction time premature initiations0.41.22.10.8-1.11.1-1.00.7-1.21.5
Std. dev. reaction times0.00.00.1-0.3-0.20.20.2-0.0-0.1-0.0
Reaction time trials completed0.00.10.30.50.00.2-0.60.1-0.30.2
Reaction time trials AUC0.00.10.30.6-0.00.2-0.50.2-0.30.2
Run reversals in cocaine runway, females1.11.32.5-0.91.6-1.30.7-0.81.1-1.3
Run reversals in cocaine runway, males1.41.62.71.1-1.21.1-1.40.9-1.41.6
Latency to leave start box in cocaine runway3.34.55.3-2.22.0-2.22.1-2.32.2-1.9
Latency to leave start box in cocaine runway, F3.13.95.3-2.21.7-2.31.5-2.31.7-2.0
Latency to leave start box in cocaine runway, M0.80.71.7-0.70.9-0.51.3-0.61.1-0.4
Std. dev. time between licks in bursts0.00.10.3-0.2-0.1-0.10.30.20.1-0.6
Total sessions with >9 infusions0.50.60.9-0.50.8-0.80.6-0.70.8-0.9
Short access day 1 total inactive lever presses1.02.02.6-1.41.2-1.41.6-1.41.4-1.3
Short access day 10 total inactive lever presses0.21.52.8-1.71.1-0.81.5-0.91.2-1.0
Short access day 1 total infusions0.00.10.10.4-0.1-0.00.4-0.20.30.2
Short access day 10 total infusions0.10.21.01.0-0.30.0-0.20.20.00.0
Short access total infusions0.30.40.6-0.20.6-0.70.7-0.80.8-0.5
Short access day 1 locomotion0.91.42.31.5-1.10.9-1.51.1-1.30.7
Short access day 10 total locomotion0.00.00.20.1-0.1-0.0-0.10.4-0.0-0.1
Short access total locomotion0.00.10.20.3-0.00.0-0.30.4-0.1-0.1
One hour access (0.3 mA shock)0.70.81.71.3-1.10.6-1.00.4-0.90.5
Compulsive drug intake0.10.20.50.2-0.40.2-0.60.1-0.70.3
One hour access (shock baseline)0.00.00.10.3-0.1-0.00.0-0.20.2-0.1
Social response proportion1.92.53.92.0-1.31.4-1.61.4-1.51.7
Social responses5.97.810.13.2-2.72.8-2.52.9-2.62.8
Social time4.87.510.03.2-2.73.0-2.12.6-2.43.0
Soleus weight4.011.713.83.7-3.43.5-3.43.2-3.43.4
Bone: stiffness0.00.00.1-0.0-0.10.10.20.20.1-0.1
Tibialis anterior weight4.716.018.54.1-4.24.3-3.93.7-4.13.6
Time to tail flick, vehicle, before self-admin0.81.02.81.2-0.80.3-1.70.4-1.20.5
Time to tail flick, vehicle, after self-admin0.10.30.7-0.30.5-0.00.9-0.30.6-0.4
Time to tail flick, test, before self-admin0.10.10.3-0.2-0.20.4-0.20.1-0.30.5
Time to tail flick, test, after self-admin2.22.43.4-1.81.5-1.41.7-1.41.6-1.3
Delta time to tail flick, vehicle, before/after SA0.91.03.5-1.10.6-0.11.9-0.51.2-0.4
Delta time to tail flick, test, before/after SA0.40.51.0-0.60.6-0.61.0-0.40.9-0.5
Tibia length3.28.811.42.9-3.13.0-3.03.4-3.02.1
Ambulatory time before self-admin0.00.10.10.1-0.3-0.1-0.2-0.3-0.30.2
Ambulatory time after self-admin0.40.61.81.3-0.60.6-0.70.6-0.70.5
Bone: tissue strength0.20.20.5-0.50.5-0.50.1-0.60.2-0.7
Total heroin consumption0.80.91.7-0.51.0-1.01.3-0.81.3-0.4
Bone: trabecular number0.71.42.41.4-0.91.1-1.50.7-1.31.2
Bone: trabecular spacing0.71.01.4-1.21.0-1.11.1-0.81.0-0.6
Bone: trabecular thickness0.30.41.01.0-0.50.4-0.90.3-0.60.4
Bone: trabecular tissue density0.20.30.6-0.50.7-0.80.3-0.60.4-0.5
Water consumed over 24 hours0.61.11.7-0.81.2-1.30.9-1.31.1-0.4
Number of responses in last shaping day0.10.20.60.4-0.20.20.10.60.3-0.7