Hub : Genes

LOC134479637

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC134479637 0.12 0.07 0.0e+00 0.15 0.16 0.16 0.16 1.5e-21 2.7e-23 2.4e-23 4.3e-23
2 BLA gene expression LOC134479637 0.04 0.04 2.3e-03 0.04 0.05 0.04 0.04 3.6e-03 1.7e-03 4.9e-03 4.3e-03
3 NAcc intron excision ratio chr7_601346_602156 0.01 0.01 6.0e-03 0.01 0.01 0.01 0.01 3.7e-03 5.4e-03 1.5e-02 5.8e-03
4 NAcc isoform ratio XR_010053179.1 0.03 0.02 1.1e-06 0.04 0.03 0.03 0.03 2.0e-06 7.6e-06 7.1e-05 7.6e-06
5 NAcc isoform ratio XR_010053180.1 0.03 0.02 1.2e-06 0.04 0.03 0.03 0.03 2.1e-06 6.4e-06 7.6e-05 6.6e-06
6 NAcc intron excision ratio chr7_600260_601040 0.02 0.02 1.2e-03 0.01 0.02 0.01 0.02 1.4e-02 5.4e-04 4.4e-03 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density0.50.93.1-0.40.90.60.7-0.71.8
Area under the delay curve0.00.00.1-0.20.1-0.10.1-0.10.1
BMI with tail6.823.827.85.2-4.9-5.3-5.05.0-3.7
BMI without tail0.94.86.32.3-2.2-2.5-2.22.2-1.8
Body weight0.94.14.82.0-2.1-2.2-2.02.0-1.9
Weight adjusted by age0.00.00.1-0.10.00.40.2-0.2-0.1
Bone surface1.22.47.4-1.01.61.11.1-1.12.7
Bone volume1.12.27.2-0.91.51.01.0-1.02.7
Breakpoint value in progressive ratio session0.50.91.2-0.90.90.81.1-1.10.7
Number of licking bursts1.75.15.52.3-2.3-2.1-2.22.2-2.3
Context. condit. distance diff. score0.40.40.50.7-0.7-0.5-0.70.7-0.7
Locomotion velocity, session 10.20.30.9-0.30.50.30.3-0.31.0
Locomotion distance, session 10.70.92.4-0.81.00.90.7-0.71.6
Locomotion velocity, session 22.93.45.3-1.71.91.81.6-1.62.3
Locomotion distance, session 25.17.29.0-2.62.82.72.5-2.53.0
Locomotion velocity, session 33.33.84.4-2.12.02.12.0-2.01.4
Locomotion distance, session 30.10.10.1-0.40.30.30.4-0.40.2
Stereotopy head waving bouts, day 34.35.15.7-2.42.42.42.2-2.22.0
Stereotopy head waving duration, day 32.12.63.2-1.71.71.81.4-1.41.5
Locomotion velocity, session 70.00.00.1-0.10.20.30.0-0.00.3
Locomotion distance, session 70.40.61.10.6-0.8-0.6-0.70.7-1.0
Stereotopy head waving bouts, day 71.11.32.0-1.01.21.20.9-0.91.4
Stereotopy head waving duration, day 71.72.13.1-1.31.51.51.3-1.31.8
Locomotion velocity, session 82.73.24.6-1.71.91.91.6-1.62.1
Locomotion distance, session 80.71.01.4-1.01.01.20.9-0.91.0
Degree of sensitization distance0.70.80.90.9-0.9-0.9-0.90.9-0.8
Degree of sensitization stereotypy0.10.10.20.20.10.1-0.20.20.5
Conditioned locomotion1.51.82.71.3-1.4-1.0-1.31.3-1.6
Cocaine response after cond. corrected3.75.55.92.4-2.4-2.0-2.42.4-2.4
Cocaine response after cond. not corrected3.44.95.32.3-2.3-1.9-2.22.2-2.3
Cocaine response before conditioning1.11.41.7-1.11.21.01.3-1.31.1
Saline control response0.20.30.40.5-0.6-0.5-0.60.6-0.6
Bone: connectivity density0.30.41.6-0.20.60.50.4-0.41.3
Bone: cortical apparent density0.71.11.31.2-1.0-1.0-1.21.2-0.7
Bone: cortical area0.20.30.50.7-0.4-0.5-0.70.70.4
Bone: cortical porosity0.10.20.4-0.10.40.40.3-0.30.6
Bone: cortical porosity0.10.10.50.10.30.30.1-0.10.7
Bone: cortical thickness0.40.61.11.0-0.7-0.8-0.90.9-0.0
Bone: cortical thickness0.40.50.60.7-0.8-0.6-0.60.6-0.8
Bone: cortical tissue density0.50.70.90.9-0.8-0.8-1.01.0-0.5
Condit. Reinf. active minus inactive responses1.31.51.7-1.21.21.31.3-1.31.0
Condit. Reinf. active-inactive response ratio0.10.10.10.3-0.3-0.2-0.30.3-0.3
Condit. Reinf. active responses3.54.54.9-2.12.12.22.2-2.22.0
Condit. Reinf. inactive responses3.84.95.1-2.22.22.22.3-2.32.1
Incentive salience index mean1.62.02.3-1.31.41.51.4-1.41.5
Condit. Reinf. lever presses1.32.03.5-1.21.41.41.2-1.21.9
Condit. Reinf. active minus inactive responses0.60.91.3-1.10.91.11.0-1.00.2
Condit. Reinf. active-inactive response ratio0.10.20.8-0.1-0.2-0.0-0.10.1-0.9
Condit. Reinf. active responses0.91.31.6-1.31.11.31.3-1.30.6
Condit. Reinf. inactive responses0.60.91.1-0.90.91.01.1-1.10.9
Condit. Reinf. lever presses1.31.92.7-1.61.41.51.5-1.50.6
Condit. Reinf. lever reinforcers received0.60.91.2-1.00.81.11.1-1.10.3
Conditioned reinforcement - actives0.00.00.20.4-0.20.0-0.00.0-0.1
Conditioned reinforcement - inactives0.30.91.11.0-1.0-0.7-1.01.0-1.1
Conditioned locomotion1.62.42.7-1.41.61.61.6-1.61.4
Patch foraging indifference point 0 sec1.64.45.42.3-2.0-2.2-2.32.3-1.2
Patch foraging indifference point AUC0.10.20.2-0.40.40.40.5-0.50.1
Delay disc. indifference point, 0s delay0.20.20.30.5-0.3-0.6-0.40.40.5
Delay disc. indifference point, 16s delay0.20.30.6-0.70.60.40.6-0.60.5
Delay disc. indifference point, 2s delay0.10.10.2-0.00.0-0.50.0-0.00.4
Delay disc. indifference point, 24s delay0.10.10.10.4-0.3-0.4-0.40.4-0.2
Delay disc. indifference point, 4s delay0.80.91.3-1.01.00.80.9-0.91.1
Delay disc. indifference point, 8s delay0.20.30.50.4-0.5-0.3-0.50.5-0.7
Indifference point function ln k0.00.10.10.2-0.3-0.2-0.40.4-0.1
Indifference point function log k0.00.10.10.2-0.3-0.2-0.40.4-0.1
Patch foraging total patch changes 0 sec1.44.04.82.2-2.0-2.1-2.22.2-1.2
Patch foraging total patch changes 12 sec1.92.62.91.7-1.6-1.6-1.61.6-1.5
Patch foraging total patch changes 18 sec0.00.00.00.1-0.0-0.1-0.10.10.1
Patch foraging total patch changes 24 sec0.10.20.80.6-0.4-0.9-0.20.2-0.1
Patch foraging total patch changes 6 sec1.42.43.21.8-1.5-1.5-1.61.6-1.0
Patch foraging time to switch 0 sec0.00.00.20.20.1-0.2-0.00.00.4
Patch foraging water rate 0 sec0.31.31.81.1-1.2-0.9-1.11.1-1.3
Patch foraging water rate 12 sec0.41.72.01.3-1.4-1.1-1.21.2-1.4
Patch foraging water rate 18 sec0.51.03.10.7-1.1-0.8-0.70.7-1.8
Patch foraging water rate 24 sec3.04.37.61.8-2.2-1.6-1.91.9-2.8
Patch foraging water rate 6 sec0.10.10.7-0.0-0.20.1-0.00.0-0.8
Seeking ratio, delayed vs. immediate footshock1.42.02.4-1.51.50.91.6-1.61.4
Distance traveled before self-admin0.71.61.7-1.31.31.31.3-1.31.1
Distance traveled after self-admin0.00.00.1-0.30.1-0.00.2-0.20.1
Extensor digitorum longus weight5.220.622.04.7-4.6-4.7-4.64.6-3.9
Bone: elastic displacement0.10.10.2-0.30.40.20.4-0.40.4
Bone: elastic work0.10.10.30.5-0.3-0.4-0.30.30.1
Bone: endosteal estimation0.61.52.01.2-1.2-1.3-1.41.4-0.7
Bone: endosteal perimeter0.20.61.3-0.70.80.70.5-0.51.2
Epididymis fat weight0.00.10.50.3-0.3-0.1-0.20.2-0.7
Delta time in closed arm before/after self-admin4.03.75.51.6-2.0-2.1-1.71.7-2.3
Delta time in open arm before/after self-admin0.40.50.60.8-0.7-0.5-0.80.8-0.5
Diff in mean of infusions in LGA sessions0.81.42.0-1.11.21.41.2-1.20.8
Delay discount exponential model param0.00.00.10.3-0.2-0.0-0.20.2-0.2
Extinction: sum of active levers before priming0.40.60.8-0.70.70.90.9-0.90.1
Active lever presses in extinction session 60.30.30.5-0.30.50.70.6-0.60.6
Bone: final force1.22.03.01.7-1.3-1.4-1.61.6-0.4
Bone: final moment1.11.82.71.7-1.3-1.3-1.51.5-0.4
Food consumed during 24 hour testing period0.10.20.30.4-0.4-0.4-0.60.6-0.3
Glucose1.11.83.01.4-1.3-1.7-1.31.3-1.0
Heart weight0.00.00.1-0.10.10.30.1-0.1-0.2
Delay discount hyperbolic model param0.00.00.00.1-0.00.2-0.00.0-0.2
Intermittent access intake day 1-15 change0.00.10.1-0.10.20.30.4-0.4-0.2
Intermittent access intake escalation0.00.10.1-0.10.20.20.3-0.3-0.2
Intermittent access intake escalation 20.10.20.2-0.40.50.40.5-0.50.2
Intermitt. access day 1 inactive lever presses0.00.20.90.1-0.30.3-0.30.3-1.0
Intermitt. access day 15 inactive lever presses0.10.81.7-0.90.81.30.8-0.80.4
Intermitt. access escalation Index0.10.20.5-0.50.40.10.5-0.50.7
Intermittent access day 1 total infusions0.10.40.40.5-0.7-0.6-0.60.6-0.6
Intermittent access day 15 total infusions0.00.00.00.2-0.1-0.1-0.10.1-0.1
Intermittent access terminal intake (last 3 days)0.10.10.2-0.10.30.30.2-0.20.5
Intermittent access total infusions0.10.10.20.4-0.3-0.2-0.30.3-0.1
Intermittent access day 1 locomotion0.20.40.80.5-0.7-0.4-0.50.5-0.9
Intermittent access day 15 total locomotion0.00.00.1-0.2-0.00.20.2-0.2-0.3
Intermittent access total locomotion0.00.00.0-0.10.00.20.2-0.2-0.1
Intermittent access standard deviation0.20.81.0-0.90.91.00.9-0.90.9
Left kidney weight0.00.10.1-0.30.0-0.10.4-0.4-0.2
Right kidney weight0.10.50.8-0.80.60.80.9-0.90.0
Cocaine induced anxiety1.33.54.1-1.71.91.42.0-2.02.0
Post-drug Anxiety2.12.44.6-1.21.70.81.6-1.62.1
Baseline Anxiety0.00.00.10.1-0.1-0.2-0.30.3-0.0
Tail length2.211.714.4-3.83.43.73.6-3.62.2
Length with tail1.04.66.1-2.52.12.42.3-2.31.0
Length without tail0.21.01.30.9-1.1-1.0-1.01.0-1.1
Times rat made contact with spout1.82.02.41.5-1.4-1.1-1.61.6-1.4
Lifetime Intake0.40.50.80.9-0.7-0.7-0.70.7-0.3
Liver weight, left0.20.30.40.5-0.6-0.5-0.50.5-0.5
Liver weight, right0.00.00.1-0.10.10.1-0.10.1-0.3
Locomotor activity5.18.09.1-2.82.93.02.8-2.82.7
Locomotor testing distance1.53.74.1-1.82.02.01.9-1.91.9
Locomotor testing rearing0.00.00.00.1-0.00.2-0.20.2-0.2
Locomotion in novel chamber0.10.10.20.3-0.3-0.4-0.10.1-0.2
Locomotion in novel chamber post-restriction1.34.14.7-2.12.21.92.1-2.11.6
Fecal boli incidents, locomotor time 10.61.51.71.2-1.2-1.2-1.21.2-1.3
Change in fecal boli incidents, locomotor task1.61.72.3-1.31.31.21.3-1.31.5
Time >=10cm from walls, locomotor time 10.10.10.20.2-0.1-0.2-0.30.30.5
Bouts of movement, locomotor time 10.40.50.9-0.80.71.00.6-0.60.4
Total resting periods, locomotor time 11.11.31.8-1.31.21.31.1-1.10.8
Rest time, locomotor task time 10.71.11.1-1.01.01.01.1-1.11.0
Distance moved, locomotor task time 10.00.10.30.5-0.2-0.3-0.30.30.4
Vertical activity count, locomotor time 10.21.31.61.2-1.2-1.2-1.01.0-0.9
Time >=10cm from walls, locomotor time 20.61.72.01.1-1.3-1.4-1.31.3-1.2
Bouts of movement, locomotor time 20.31.01.2-1.00.91.10.8-0.81.1
Total resting periods, locomotor time 20.31.11.6-1.11.01.10.9-0.91.2
Rest time, locomotor task time 20.30.50.8-0.70.70.60.6-0.60.9
Distance moved, locomotor task time 20.10.20.50.4-0.5-0.2-0.30.3-0.7
Vertical activity count, locomotor time 20.92.12.81.4-1.6-1.4-1.31.3-1.7
Light reinforcement 12.19.410.8-3.13.13.33.1-3.12.7
Light reinforcement 21.43.13.7-1.91.81.91.7-1.71.6
Bone: marrow area0.61.52.01.2-1.1-1.3-1.41.4-0.7
Bone: maximum diameter0.40.92.1-0.81.00.80.7-0.71.4
Bone: maximum force1.32.53.61.9-1.5-1.6-1.81.8-0.6
Bone: maximum moment1.22.33.41.8-1.5-1.6-1.71.7-0.6
Mean time between licks in bursts0.10.40.6-0.70.60.80.5-0.50.3
Mean num. licks in bursts0.51.31.7-1.11.21.31.0-1.01.2
Cd content in liver0.10.10.1-0.20.30.30.3-0.30.4
Co content in liver2.53.03.9-1.91.72.01.8-1.81.1
Cu content in liver0.20.20.30.4-0.2-0.4-0.60.60.3
Fe content in liver0.60.70.80.9-0.9-0.7-0.90.9-0.9
K content in liver1.51.51.8-1.21.31.11.2-1.21.4
Mg content in liver1.31.41.6-1.21.21.31.1-1.11.1
Mn content in liver3.43.96.1-1.92.01.81.8-1.82.5
Na content in liver0.10.10.20.4-0.1-0.5-0.30.30.2
Rb content in liver0.10.10.30.3-0.0-0.2-0.50.50.4
Se content in liver0.00.00.00.2-0.2-0.2-0.10.1-0.1
Sr content in liver0.10.10.3-0.30.20.30.5-0.5-0.2
Zn content in liver0.70.81.1-1.10.81.11.0-1.0-0.2
Bone: minimum diameter0.10.20.20.4-0.2-0.4-0.50.50.5
Time in familiar zone, hab. session 12.42.63.5-1.91.61.71.7-1.70.9
Time in novel zone, hab. session 10.91.01.71.3-0.9-1.0-1.11.1-0.1
Total zone transitions, hab. session 11.11.62.8-1.11.31.21.1-1.11.7
Total locomotion distance, hab. session 13.75.27.4-2.22.42.22.1-2.12.7
Locomotion velocity, hab. session 13.55.06.4-2.22.32.22.1-2.12.5
Time in familiar zone, hab. session 23.94.45.8-2.31.92.22.4-2.41.0
Time in novel zone, hab. session 24.14.56.02.4-1.9-2.2-2.42.4-0.9
Total zone transitions, hab. session 20.30.41.8-0.10.40.30.2-0.21.3
Total locomotion distance, hab. session 21.72.23.0-1.41.51.41.5-1.51.7
Locomotion velocity, hab. session 22.22.94.3-1.61.71.61.6-1.62.1
Novel to familiar place preference ratio1.01.31.91.4-1.0-1.2-1.31.3-0.2
Novelty place preference0.60.81.11.1-0.7-0.9-1.01.0-0.0
Time in novel zone, NPP test1.01.21.71.3-1.0-1.2-1.31.3-0.2
Total zone transitions, NPP test0.10.10.4-0.00.20.1-0.00.00.7
Total locomotion distance, NPP test0.40.61.4-0.60.70.60.6-0.61.2
Locomotion velocity, NPP test0.71.01.8-0.91.00.90.9-0.91.3
Intraocular pressure0.00.10.4-0.2-0.00.1-0.00.0-0.6
Delta distance traveled before/after self-admin0.60.61.00.6-0.8-1.0-0.80.8-0.8
Delta ambulatory time before/after self-admin0.20.30.60.5-0.6-0.8-0.60.6-0.3
Parametrial fat weight0.30.61.20.8-0.8-1.1-0.80.8-0.5
Pavlov. Cond. lever latency0.70.92.00.6-0.9-0.8-0.80.8-1.4
Pavlov. Cond. magazine entry latency1.62.02.3-1.51.41.51.5-1.51.1
Pavlov. Cond. change in total contacts0.10.10.10.4-0.3-0.4-0.20.2-0.2
Pavlov. Cond. index score1.11.41.7-1.11.21.21.2-1.21.3
Pavlov. Cond. latency score1.31.72.4-1.11.31.21.2-1.21.5
Pavlov. Cond. lever contacts0.50.61.6-0.50.70.70.7-0.71.3
Pavlov. Cond. magazine entry number0.50.70.80.9-0.8-0.9-0.90.9-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.50.1-0.3-0.2-0.00.0-0.7
Pavlov. Cond. lever-magazine prob. diff.1.11.41.5-1.11.21.21.2-1.21.2
Pavlov. Cond. response bias0.50.60.8-0.80.80.80.9-0.90.6
Pavlov. Cond. lever latency1.52.12.81.7-1.5-1.4-1.51.5-1.0
Pavlov. Cond. magazine entry latency2.12.93.6-1.91.71.71.8-1.81.2
Pavlov. Cond. change in total contacts0.40.91.3-1.10.90.91.0-1.00.5
Pavlov. Cond. index score1.42.23.1-1.71.51.51.5-1.51.0
Pavlov. Cond. latency score1.72.83.6-1.91.71.71.7-1.71.2
Pavlov. Cond. lever contacts1.01.52.2-1.51.31.21.3-1.30.7
Pavlov. Cond. magazine entry number2.43.13.82.0-1.8-1.7-1.81.8-1.3
Pavlov. Cond. intertrial magazine entries1.02.12.31.5-1.5-1.5-1.41.4-1.4
Pavlov. Cond. lever-magazine prob. diff.1.72.63.4-1.81.71.61.7-1.71.1
Pavlov. Cond. response bias1.72.33.4-1.81.51.51.6-1.60.8
Time in closed arm before self-admin0.10.20.6-0.30.40.00.2-0.20.8
Time in closed arm after self-admin0.60.72.10.5-0.8-1.4-0.70.7-0.7
Time in open arm before self-admin0.00.00.10.3-0.20.1-0.20.2-0.2
Time in open arm after self-admin1.71.82.41.6-1.4-0.8-1.51.5-1.3
Bone: periosteal estimation0.41.01.51.1-0.8-1.0-1.21.20.0
Bone: periosteal perimeter0.20.31.3-0.30.50.30.2-0.21.1
Bone: post-yield work0.71.21.41.0-1.1-1.1-1.21.2-0.9
Progressive ratio test 1 active lever presses0.30.60.80.9-0.8-0.7-0.80.8-0.7
Progressive ratio test 1 breakpoint0.40.60.90.9-0.8-0.7-0.80.8-0.7
Progressive ratio test 1 inactive lever presses0.10.20.4-0.30.30.50.6-0.60.3
Progressive ratio test 2 active lever presses0.00.10.2-0.10.20.50.3-0.30.2
Progressive ratio test 2 breakpoint0.10.20.4-0.30.30.60.4-0.40.3
Progressive ratio test 2 inactive lever presses0.00.00.10.30.00.30.0-0.00.3
Incentive Sensitization - Responses0.20.50.8-0.70.60.90.7-0.70.4
Incentive Sensitization - Breakpoint0.30.81.2-0.90.81.10.9-0.90.6
Sum of active levers in priming session hrs 5-60.00.00.0-0.10.20.00.2-0.20.1
Progressive ratio0.71.92.31.3-1.5-1.0-1.51.5-1.4
Food seeking constrained by brief footshock1.41.72.0-1.31.31.41.4-1.40.9
Seeking ratio, punishment vs. effort1.43.13.8-1.81.81.51.9-1.91.4
Retroperitoneal fat weight2.511.213.43.3-3.5-3.7-3.23.2-3.3
Reaction time number correct0.72.33.11.4-1.6-1.4-1.51.5-1.8
Reaction time mean minus median0.31.92.3-1.51.41.11.5-1.51.1
Reaction time mean minus median AUC0.53.44.0-1.91.91.51.9-1.92.0
Reaction time num false alarms0.20.40.60.6-0.8-0.4-0.60.6-0.6
Reaction time num false alarms AUC0.20.50.70.6-0.8-0.5-0.70.7-0.8
Reaction time trials correct on left0.72.33.11.4-1.6-1.4-1.51.5-1.8
Reaction time trials on left0.62.22.81.3-1.6-1.4-1.41.4-1.7
Reaction time mean1.02.12.6-1.51.51.21.4-1.41.6
Reaction time mean AUC0.40.91.6-1.01.00.60.9-0.91.2
Median of all reaction times0.81.21.9-1.11.20.91.0-1.01.4
Reaction time omissions0.10.10.3-0.30.3-0.10.4-0.40.6
Reaction time false alarm rate0.00.00.1-0.10.10.20.1-0.10.2
Reaction time premature initiation rate0.91.52.0-1.21.01.41.4-1.40.4
Reaction time premature initiations0.10.20.4-0.40.10.50.5-0.5-0.6
Std. dev. reaction times0.41.31.5-1.21.20.81.2-1.21.2
Reaction time trials completed0.62.22.81.3-1.6-1.4-1.41.4-1.7
Reaction time trials AUC0.72.63.61.5-1.7-1.4-1.61.6-1.9
Run reversals in cocaine runway, females3.13.53.9-2.01.82.01.9-1.91.7
Run reversals in cocaine runway, males2.42.73.0-1.61.71.31.7-1.71.7
Latency to leave start box in cocaine runway0.30.51.2-0.50.70.30.6-0.61.1
Latency to leave start box in cocaine runway, F0.40.51.8-0.40.70.20.5-0.51.3
Latency to leave start box in cocaine runway, M0.00.00.1-0.0-0.10.00.1-0.1-0.3
Std. dev. time between licks in bursts0.61.01.6-1.01.11.00.8-0.81.2
Total sessions with >9 infusions0.30.30.80.7-0.6-0.9-0.40.4-0.2
Short access day 1 total inactive lever presses0.10.10.2-0.50.20.50.3-0.3-0.1
Short access day 10 total inactive lever presses0.10.41.50.3-0.6-0.3-0.50.5-1.2
Short access day 1 total infusions0.20.40.70.8-0.7-0.9-0.60.6-0.3
Short access day 10 total infusions0.20.30.40.5-0.6-0.6-0.50.5-0.5
Short access total infusions0.40.50.70.9-0.8-0.8-0.70.7-0.3
Short access day 1 locomotion0.10.10.3-0.40.20.30.5-0.5-0.0
Short access day 10 total locomotion0.10.30.6-0.50.30.70.5-0.5-0.4
Short access total locomotion0.00.10.1-0.20.10.10.3-0.3-0.2
One hour access (0.3 mA shock)0.20.30.50.7-0.6-0.4-0.40.4-0.6
Compulsive drug intake0.10.10.1-0.40.30.10.4-0.40.4
One hour access (shock baseline)0.00.00.10.2-0.10.1-0.00.0-0.2
Social response proportion1.31.62.7-1.31.21.61.2-1.21.1
Social responses9.913.016.1-3.73.74.03.6-3.63.1
Social time1.01.61.81.3-1.3-1.2-1.31.3-1.2
Soleus weight4.011.914.83.8-3.5-3.8-3.43.4-2.5
Bone: stiffness2.95.26.72.6-2.3-2.2-2.52.5-1.4
Tibialis anterior weight1.34.45.72.3-2.0-2.4-2.22.2-1.4
Time to tail flick, vehicle, before self-admin1.41.72.1-1.41.40.61.4-1.41.5
Time to tail flick, vehicle, after self-admin0.00.10.5-0.1-0.10.30.0-0.0-0.7
Time to tail flick, test, before self-admin1.61.82.3-1.41.31.21.4-1.41.5
Time to tail flick, test, after self-admin0.00.00.2-0.10.2-0.1-0.00.00.4
Delta time to tail flick, vehicle, before/after SA2.32.53.61.5-1.6-0.9-1.71.7-1.9
Delta time to tail flick, test, before/after SA0.50.61.10.7-0.7-0.6-0.80.8-1.0
Tibia length0.71.82.4-1.51.41.61.4-1.40.7
Ambulatory time before self-admin0.10.30.5-0.50.60.70.6-0.60.5
Ambulatory time after self-admin0.00.00.0-0.00.1-0.10.1-0.10.1
Bone: tissue strength4.04.25.72.4-2.0-2.2-2.22.2-1.2
Total heroin consumption2.53.03.3-1.71.71.71.8-1.81.5
Bone: trabecular number1.01.83.3-1.11.41.11.3-1.31.8
Bone: trabecular spacing1.01.43.60.8-1.2-0.8-1.01.0-1.9
Bone: trabecular thickness1.21.65.4-0.71.31.00.8-0.82.3
Bone: trabecular tissue density4.98.79.43.1-3.0-3.0-2.92.9-2.6
Water consumed over 24 hours0.10.20.40.6-0.3-0.4-0.60.60.2
Number of responses in last shaping day0.70.91.4-0.90.91.01.2-1.20.4