LOC134479380

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression LOC134479380 0.16 0.11 9.7e-05 0.05 0.07 0.06 0.07 5.0e-03 8.7e-04 1.9e-03 8.6e-04
2 PL isoform ratio XR_010052659.1 0.05 0.04 3.9e-04 0.02 0.02 0.02 0.02 1.7e-03 1.1e-03 3.3e-03 3.2e-03
3 NAcc alternative polyA XR_010052657.1 0.02 0.01 1.3e-03 0.01 0.01 0.01 0.01 6.8e-03 3.4e-03 3.3e-03 8.1e-03
4 NAcc alternative polyA XR_010052663.1 0.02 0.01 8.6e-04 0.01 0.01 0.01 0.01 6.3e-03 2.9e-03 2.6e-03 4.9e-03
5 OFC intron excision ratio chr6_72371612_72375725 0.13 0.09 7.1e-03 0.07 0.09 0.07 0.04 8.5e-03 3.8e-03 1.1e-02 3.4e-02
6 PL intron excision ratio chr6_72371612_72397481 0.03 0.03 5.5e-03 0.02 0.02 0.01 0.01 3.3e-03 4.2e-03 1.3e-02 2.5e-02
7 OFC intron excision ratio chr6_72371612_72397481 0.14 0.09 5.3e-03 0.07 0.1 0.09 0.06 8.1e-03 2.3e-03 4.3e-03 1.5e-02
8 NAcc isoform ratio XR_010052659.1 0.02 0.02 5.1e-03 0.01 0.01 0.01 0.01 1.1e-02 6.0e-03 6.8e-03 8.6e-03
9 Brain alternative polyA XR_010052657.1 0.06 0.05 1.9e-03 0.02 0.01 0.03 0.01 2.3e-03 5.5e-02 6.1e-04 1.3e-02
10 Brain gene expression LOC134479380 0.04 0.03 1.9e-03 0 0.02 0.01 0.01 2.7e-01 2.5e-03 1.9e-02 6.2e-02
11 Brain alternative polyA XR_010052663.1 0.06 0.05 2.1e-03 0.02 0.01 0.03 0.01 2.5e-03 6.9e-02 6.7e-04 1.4e-02
12 PL mRNA stability LOC134479380 0.03 0.02 1.6e-03 0.02 0.02 0.01 0.01 4.6e-03 6.1e-03 8.5e-03 1.4e-02
13 IC alternative polyA XR_010052663.1 0.15 0.08 1.2e-05 0.09 0.12 0.12 0.11 1.7e-04 1.6e-05 1.4e-05 3.2e-05
14 IC alternative polyA XR_010052657.1 0.15 0.08 1.4e-05 0.09 0.11 0.11 0.1 2.1e-04 2.2e-05 1.7e-05 4.4e-05
15 BLA alternative polyA XR_010052663.1 0.07 0.05 5.9e-03 0.01 0.01 0.01 0.01 9.1e-02 1.0e-01 5.1e-02 8.9e-02
16 Brain isoform ratio XR_010052657.1 0.09 0.07 3.8e-04 0.01 0.03 0.02 0.02 2.6e-02 1.1e-03 1.0e-02 6.4e-03
17 BLA alternative polyA XR_010052657.1 0.07 0.06 4.8e-03 0.01 0.01 0.01 0.01 9.1e-02 9.7e-02 7.1e-02 9.2e-02
18 NAcc intron excision ratio chr6_72371612_72375725 0.06 0.03 1.4e-07 0.05 0.05 0.05 0.05 1.7e-07 8.1e-08 4.2e-08 1.3e-07
19 BLA mRNA stability LOC134479380 0.05 0.04 7.9e-03 0.01 0.03 0.02 0.02 7.0e-02 8.6e-03 3.4e-02 1.9e-02
20 BLA isoform ratio XR_010052657.1 0.1 0.07 1.7e-04 0.03 0.04 0.03 0.03 7.0e-03 3.7e-03 1.1e-02 9.8e-03
21 PL intron excision ratio chr6_72371612_72375725 0.06 0.04 3.4e-05 0.04 0.04 0.03 0.04 5.1e-05 6.5e-05 4.0e-04 9.0e-05
22 IL gene expression LOC134479380 0.14 0.1 8.6e-03 0.03 0.05 0.08 0.07 7.0e-02 2.3e-02 5.8e-03 1.0e-02
23 IC isoform ratio XR_010052657.1 0.11 0.07 8.6e-04 0.06 0.06 0.07 0.05 1.4e-03 2.1e-03 6.8e-04 4.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density4.27.217.0-3.13.83.0-3.12.1-2.3-2.02.24.1-2.0-4.1-3.6-3.23.2-0.43.90.2-0.3-2.62.1-1.01.81.3
Area under the delay curve0.60.62.10.6-0.9-0.60.6-0.00.4-0.0-0.1-1.10.01.10.91.0-1.0-0.4-1.30.41.01.0-0.81.0-1.5-0.5
BMI with tail0.72.46.4-0.41.40.8-0.8-0.50.30.6-0.51.60.7-1.6-1.6-1.61.61.62.3-1.7-2.0-2.11.8-2.22.22.5
BMI without tail1.95.712.0-2.33.12.6-2.71.3-1.8-1.11.03.0-0.8-2.9-3.2-3.23.2-0.23.50.0-1.1-3.13.0-1.92.52.1
Body weight1.88.115.5-3.23.93.5-3.52.4-2.6-2.22.13.5-1.9-3.5-3.8-3.63.6-1.43.71.2-0.1-3.23.0-1.01.91.9
Weight adjusted by age0.81.22.81.3-1.1-0.50.5-1.31.31.4-1.7-1.21.71.2-0.20.0-0.00.8-0.5-0.7-1.3-0.60.9-1.21.21.4
Bone surface4.37.914.5-3.73.73.4-3.43.2-3.1-3.13.33.8-3.2-3.8-3.3-2.92.9-2.03.01.81.3-1.71.40.60.4-0.0
Bone volume4.88.616.8-3.83.93.6-3.63.1-3.1-2.93.04.1-2.9-4.1-3.6-3.33.3-1.83.41.60.8-2.21.90.01.00.5
Breakpoint value in progressive ratio session2.53.05.5-2.12.42.2-2.21.7-1.8-1.71.62.3-1.5-2.3-2.3-2.12.1-1.02.10.80.4-1.51.5-0.10.80.5
Number of licking bursts0.20.40.70.9-0.8-0.80.8-0.60.70.6-0.6-0.90.50.90.80.7-0.70.4-0.6-0.3-0.10.5-0.50.1-0.2-0.1
Context. condit. distance diff. score1.51.95.60.50.40.5-0.5-0.80.51.0-1.3-0.21.40.3-1.1-1.51.50.31.2-0.3-1.9-2.22.4-2.02.42.3
Locomotion velocity, session 10.30.30.6-0.60.60.7-0.70.8-0.7-0.80.70.6-0.7-0.6-0.7-0.50.5-0.70.30.70.6-0.20.30.4-0.2-0.3
Locomotion distance, session 10.50.61.51.0-1.2-0.70.8-0.50.90.5-0.5-1.00.50.90.81.1-1.10.3-1.2-0.30.30.9-0.80.6-0.7-0.4
Locomotion velocity, session 21.21.43.10.8-1.4-1.01.0-0.10.60.0-0.0-1.3-0.11.21.31.6-1.6-0.4-1.70.51.11.8-1.71.5-1.6-1.4
Locomotion distance, session 21.41.94.71.0-1.5-1.31.3-0.30.90.2-0.0-1.1-0.11.01.52.1-2.10.2-1.8-0.21.12.1-2.21.6-1.9-1.6
Locomotion velocity, session 30.70.82.10.3-0.8-0.70.70.10.1-0.20.2-0.7-0.30.60.91.1-1.1-0.4-1.30.51.11.4-1.31.3-1.5-1.3
Locomotion distance, session 30.20.20.70.3-0.3-0.80.8-0.40.60.3-0.10.00.1-0.00.50.7-0.70.7-0.2-0.70.10.6-0.80.1-0.4-0.4
Stereotopy head waving bouts, day 31.41.74.21.7-1.9-1.41.4-1.21.21.1-1.3-2.01.22.01.61.5-1.50.3-1.8-0.2-0.21.1-0.80.2-0.5-0.4
Stereotopy head waving duration, day 30.80.92.21.1-1.4-1.01.0-0.60.70.5-0.6-1.50.51.51.21.3-1.3-0.1-1.50.20.21.1-0.90.6-0.7-0.7
Locomotion velocity, session 71.71.97.31.2-0.4-1.31.3-1.71.81.7-1.40.21.4-0.30.20.4-0.42.60.7-2.7-1.9-0.3-0.2-1.71.01.3
Locomotion distance, session 70.81.14.41.0-0.4-1.31.2-1.31.41.3-1.00.11.0-0.10.50.6-0.62.10.4-2.1-1.10.1-0.5-1.00.40.7
Stereotopy head waving bouts, day 70.40.51.4-0.60.30.5-0.50.9-0.7-1.00.90.2-0.9-0.2-0.3-0.10.1-1.2-0.21.21.00.3-0.20.9-0.5-0.8
Stereotopy head waving duration, day 70.20.30.8-0.1-0.3-0.00.00.4-0.2-0.50.4-0.2-0.50.10.20.4-0.4-0.6-0.60.60.80.7-0.60.9-0.7-0.8
Locomotion velocity, session 80.20.20.8-0.30.20.4-0.40.6-0.5-0.60.50.0-0.5-0.0-0.3-0.10.1-0.9-0.10.90.60.10.10.5-0.3-0.4
Locomotion distance, session 80.10.10.50.20.00.2-0.2-0.20.30.2-0.4-0.10.40.0-0.5-0.40.4-0.00.40.0-0.4-0.60.6-0.40.70.7
Degree of sensitization distance0.20.20.60.00.4-0.00.0-0.20.10.3-0.10.40.2-0.4-0.2-0.20.20.70.6-0.7-0.6-0.40.3-0.60.50.5
Degree of sensitization stereotypy1.82.03.6-1.81.51.6-1.61.9-1.8-1.91.81.4-1.8-1.4-1.3-1.11.1-1.80.71.71.4-0.30.41.0-0.4-0.7
Conditioned locomotion0.70.82.2-0.1-0.7-0.10.20.4-0.5-0.50.2-0.9-0.31.00.80.6-0.6-1.3-1.41.41.40.9-0.51.5-1.4-1.0
Cocaine response after cond. corrected0.81.02.01.1-0.8-1.00.9-1.41.31.4-1.4-0.81.40.80.60.3-0.31.2-0.1-1.1-1.3-0.20.1-1.00.61.0
Cocaine response after cond. not corrected0.60.81.61.0-0.6-0.80.8-1.21.21.3-1.2-0.61.20.60.50.2-0.21.20.1-1.1-1.2-0.30.2-1.00.70.9
Cocaine response before conditioning0.10.10.5-0.10.10.0-0.00.2-0.1-0.30.40.2-0.4-0.20.20.4-0.40.1-0.1-0.10.40.5-0.60.4-0.3-0.7
Saline control response0.60.92.0-0.80.91.0-1.10.3-0.6-0.20.10.90.0-0.9-1.1-1.31.3-0.11.20.0-0.6-1.31.4-1.01.41.0
Bone: connectivity density6.19.623.6-3.74.43.4-3.52.5-2.7-2.42.74.9-2.5-4.8-4.1-3.63.6-0.44.50.1-0.2-2.82.2-1.02.01.3
Bone: cortical apparent density1.31.73.41.5-1.0-1.31.2-1.81.81.9-1.8-0.81.80.80.80.5-0.51.8-0.0-1.8-1.7-0.20.1-1.51.31.2
Bone: cortical area2.94.48.0-2.72.32.5-2.52.8-2.7-2.82.82.1-2.8-2.0-1.9-1.51.5-2.61.22.52.0-0.50.51.6-0.4-0.9
Bone: cortical porosity0.50.51.1-0.80.50.8-0.81.0-0.8-1.00.90.4-0.9-0.3-0.6-0.30.3-1.10.11.10.90.10.00.8-0.5-0.4
Bone: cortical porosity1.01.12.9-1.10.71.0-1.01.4-1.2-1.41.40.4-1.4-0.3-0.7-0.30.3-1.70.01.71.30.2-0.11.2-0.8-0.8
Bone: cortical thickness0.20.30.6-0.70.70.7-0.70.5-0.5-0.50.50.8-0.5-0.8-0.7-0.60.6-0.30.70.30.0-0.50.40.00.70.4
Bone: cortical thickness0.40.51.10.9-0.6-0.50.5-1.01.01.0-1.0-0.61.00.60.20.3-0.30.7-0.0-0.7-1.0-0.30.2-0.90.50.7
Bone: cortical tissue density1.31.83.61.5-1.1-1.31.3-1.91.81.9-1.8-0.81.80.80.90.5-0.51.9-0.1-1.8-1.8-0.20.0-1.51.21.2
Condit. Reinf. active minus inactive responses1.61.83.6-1.61.11.4-1.41.9-1.8-1.91.91.0-1.9-1.0-0.9-0.50.5-1.90.31.81.70.2-0.21.4-0.9-1.1
Condit. Reinf. active-inactive response ratio0.10.20.4-0.30.40.6-0.60.4-0.3-0.40.30.2-0.3-0.2-0.6-0.40.4-0.60.30.60.1-0.40.5-0.00.20.2
Condit. Reinf. active responses2.73.46.9-2.11.21.7-1.62.5-2.4-2.62.61.2-2.6-1.2-0.8-0.30.3-2.4-0.12.42.50.7-0.62.2-1.7-2.0
Condit. Reinf. inactive responses1.72.14.8-1.50.50.7-0.71.8-1.8-1.92.00.7-2.0-0.7-0.00.3-0.3-1.6-0.61.62.21.3-1.22.1-2.0-2.1
Incentive salience index mean3.54.39.7-2.41.71.8-1.82.9-2.5-2.93.11.7-3.1-1.7-1.0-0.40.4-2.30.32.22.80.9-0.92.4-1.8-2.2
Condit. Reinf. lever presses2.02.87.0-1.81.31.0-0.92.1-1.7-2.22.61.6-2.6-1.6-0.50.2-0.2-1.10.21.02.31.3-1.62.1-1.8-2.3
Condit. Reinf. active minus inactive responses0.70.92.30.1-0.6-0.80.80.3-0.1-0.40.5-0.5-0.60.41.01.1-1.1-0.3-1.30.31.31.5-1.41.5-1.5-1.5
Condit. Reinf. active-inactive response ratio0.40.51.10.6-0.8-0.90.9-0.30.40.2-0.2-0.70.10.70.90.9-0.90.1-1.1-0.00.51.0-0.90.7-0.9-0.7
Condit. Reinf. active responses1.11.54.2-0.5-0.0-0.40.41.0-0.6-1.11.40.3-1.5-0.30.71.1-1.1-0.5-0.90.42.01.8-2.02.0-1.9-2.0
Condit. Reinf. inactive responses0.50.71.9-0.90.90.5-0.51.0-0.7-1.11.41.2-1.4-1.2-0.40.0-0.0-0.10.50.01.00.5-0.80.9-0.7-0.9
Condit. Reinf. lever presses3.04.29.0-2.52.22.1-2.12.9-2.6-2.93.02.2-3.0-2.1-1.6-1.11.1-2.21.02.02.30.1-0.11.7-0.9-1.2
Condit. Reinf. lever reinforcers received2.02.97.3-1.61.00.7-0.62.1-1.7-2.32.51.2-2.6-1.2-0.10.3-0.3-1.5-0.41.42.71.5-1.62.5-2.0-2.3
Conditioned reinforcement - actives1.01.74.0-1.31.12.0-2.01.7-1.2-1.61.41.0-1.4-1.0-1.7-1.11.1-1.60.71.61.3-0.60.81.0-0.30.3
Conditioned reinforcement - inactives1.21.83.5-1.51.51.8-1.81.4-1.3-1.31.11.6-1.1-1.6-1.9-1.61.6-1.01.30.80.7-1.21.30.10.41.2
Conditioned locomotion0.60.81.8-0.91.01.3-1.30.9-0.6-0.90.81.0-0.7-1.0-1.3-1.11.1-0.61.00.50.3-0.80.90.00.10.7
Patch foraging indifference point 0 sec2.24.010.0-2.01.41.9-1.82.8-2.2-2.92.91.3-3.0-1.3-1.2-0.30.3-2.3-0.02.23.20.9-0.82.7-1.8-1.9
Patch foraging indifference point AUC1.82.66.5-1.60.61.2-1.12.0-1.8-2.12.00.6-2.1-0.6-1.0-0.00.0-2.4-0.52.52.50.9-0.82.6-1.5-1.8
Delay disc. indifference point, 0s delay0.10.10.40.2-0.3-0.40.4-0.10.00.1-0.2-0.50.20.50.30.3-0.30.1-0.7-0.10.30.20.1-0.00.40.2
Delay disc. indifference point, 16s delay0.40.42.6-0.4-0.00.4-0.40.7-0.6-0.70.6-0.2-0.60.20.10.2-0.2-0.9-0.50.91.10.5-0.31.0-1.6-0.8
Delay disc. indifference point, 2s delay0.30.40.8-0.60.40.5-0.50.9-0.9-0.90.80.4-0.8-0.4-0.3-0.20.2-0.7-0.10.80.50.1-0.00.7-0.9-0.8
Delay disc. indifference point, 24s delay1.01.13.4-0.1-0.5-0.10.10.8-0.5-0.80.7-0.9-0.81.00.70.8-0.8-1.5-1.41.61.51.2-0.91.7-1.9-1.3
Delay disc. indifference point, 4s delay2.22.44.62.1-2.0-1.81.8-1.82.01.7-1.8-2.11.72.11.71.5-1.51.1-1.5-1.1-0.30.8-0.7-0.2-0.20.5
Delay disc. indifference point, 8s delay0.30.31.50.1-0.4-0.30.30.30.2-0.30.3-0.3-0.40.30.40.6-0.6-0.3-0.70.30.90.8-0.70.8-1.2-0.4
Indifference point function ln k0.20.31.00.40.20.0-0.1-0.40.40.5-0.40.10.5-0.10.0-0.30.30.90.6-1.0-0.8-0.60.4-1.00.40.8
Indifference point function log k0.20.31.00.40.20.0-0.1-0.40.40.5-0.40.10.5-0.10.0-0.30.30.90.6-1.0-0.8-0.60.4-1.00.40.8
Patch foraging total patch changes 0 sec2.44.511.2-2.21.42.0-1.93.0-2.3-3.03.11.4-3.1-1.4-1.2-0.30.3-2.5-0.12.43.41.0-0.92.9-1.9-2.0
Patch foraging total patch changes 12 sec3.14.08.2-2.21.42.0-1.92.8-2.4-2.92.81.4-2.9-1.5-1.5-0.50.5-2.60.02.52.90.7-0.52.6-1.3-1.9
Patch foraging total patch changes 18 sec0.81.24.0-0.70.20.5-0.51.3-0.9-1.41.40.3-1.5-0.4-0.60.4-0.4-1.3-0.51.32.01.1-1.12.0-1.1-1.4
Patch foraging total patch changes 24 sec3.05.210.6-2.61.92.3-2.33.2-2.6-3.23.21.8-3.3-1.9-2.2-0.90.9-2.70.42.63.10.4-0.32.7-1.3-1.6
Patch foraging total patch changes 6 sec2.43.77.4-2.11.52.1-2.12.7-2.3-2.72.61.4-2.6-1.4-1.6-0.80.8-2.70.42.62.70.2-0.02.3-0.9-1.2
Patch foraging time to switch 0 sec5.912.024.84.1-2.6-3.02.9-4.84.44.9-4.9-2.45.02.31.70.9-0.94.4-0.0-4.2-4.9-1.31.1-4.43.03.6
Patch foraging water rate 0 sec2.45.010.4-2.92.02.0-2.03.1-3.1-3.23.21.9-3.2-1.9-1.4-0.80.8-2.50.42.43.10.5-0.42.5-1.5-1.9
Patch foraging water rate 12 sec2.65.49.7-3.03.12.9-2.92.6-2.9-2.52.52.9-2.4-2.9-2.6-2.52.5-1.82.51.60.9-1.81.70.00.80.5
Patch foraging water rate 18 sec1.42.13.6-1.81.91.8-1.91.5-1.8-1.41.31.5-1.2-1.5-1.5-1.91.9-1.31.51.10.4-1.41.5-0.30.90.7
Patch foraging water rate 24 sec2.02.95.1-2.12.32.0-2.01.4-1.9-1.31.32.2-1.2-2.1-2.2-2.12.1-0.92.20.8-0.1-1.81.7-0.71.20.9
Patch foraging water rate 6 sec3.55.111.1-3.22.52.5-2.53.1-3.3-3.13.02.2-2.9-2.1-2.0-1.71.7-2.61.12.52.2-0.50.61.3-0.7-1.1
Seeking ratio, delayed vs. immediate footshock1.31.64.01.0-1.3-1.71.7-1.01.20.9-0.5-0.60.50.51.71.9-1.91.4-1.2-1.3-0.01.7-2.00.3-1.2-1.1
Distance traveled before self-admin0.70.92.6-0.8-0.00.4-0.41.1-1.1-1.21.0-0.0-1.1-0.0-0.10.2-0.2-1.4-0.91.41.60.8-0.51.5-1.3-1.3
Distance traveled after self-admin0.10.10.3-0.20.30.0-0.00.0-0.1-0.00.10.5-0.0-0.5-0.4-0.10.10.50.3-0.6-0.2-0.20.1-0.30.40.2
Extensor digitorum longus weight2.710.819.6-3.84.24.2-4.22.9-3.6-2.72.43.6-2.1-3.5-4.0-4.44.4-2.53.72.30.3-3.73.8-0.82.21.9
Bone: elastic displacement0.20.30.70.5-0.2-0.30.2-0.60.60.7-0.7-0.20.70.2-0.1-0.10.10.60.2-0.6-0.8-0.40.4-0.80.70.9
Bone: elastic work1.11.43.1-1.31.61.4-1.40.8-0.9-0.70.81.7-0.7-1.7-1.7-1.51.5-0.21.70.1-0.4-1.31.1-0.71.20.9
Bone: endosteal estimation1.84.09.9-2.21.62.2-2.12.7-2.6-2.72.51.0-2.5-1.0-1.3-1.01.0-3.20.23.12.40.00.31.9-1.7-1.7
Bone: endosteal perimeter2.65.511.8-2.51.62.1-2.03.2-2.9-3.33.21.2-3.2-1.1-1.0-0.50.5-3.4-0.23.43.30.8-0.62.9-2.3-2.6
Epididymis fat weight0.61.95.30.30.60.1-0.2-1.00.81.1-1.10.91.2-0.9-1.1-1.11.11.91.7-2.0-1.9-1.71.4-2.11.82.3
Delta time in closed arm before/after self-admin1.71.63.4-1.41.51.6-1.61.0-1.3-0.90.81.7-0.7-1.7-1.2-1.81.8-0.41.60.4-0.2-1.41.4-0.50.90.6
Delta time in open arm before/after self-admin0.20.20.6-0.50.40.4-0.40.5-0.4-0.50.50.4-0.5-0.4-0.8-0.20.2-0.30.20.20.6-0.10.10.4-0.2-0.0
Diff in mean of infusions in LGA sessions0.20.30.80.3-0.4-0.80.8-0.30.30.3-0.1-0.00.1-0.00.10.9-0.90.8-0.5-0.8-0.00.7-0.80.1-0.5-0.6
Delay discount exponential model param0.91.02.5-0.91.20.9-0.90.3-0.7-0.30.31.4-0.2-1.4-1.2-1.21.20.21.5-0.3-0.9-1.21.0-1.01.60.6
Extinction: sum of active levers before priming3.43.79.4-2.02.71.9-2.01.0-1.4-0.91.13.0-1.0-2.9-2.1-2.52.50.03.1-0.1-0.9-2.21.8-1.32.21.3
Active lever presses in extinction session 64.44.38.5-2.32.42.9-2.92.3-2.4-2.22.02.1-1.9-2.1-2.4-2.42.4-2.21.92.10.9-1.71.90.51.10.5
Bone: final force1.22.03.5-1.51.71.8-1.81.1-1.2-1.00.91.5-0.8-1.5-1.8-1.91.9-1.21.71.1-0.3-1.71.7-0.61.21.0
Bone: final moment1.52.44.2-1.71.92.0-2.01.4-1.5-1.21.01.6-0.9-1.5-1.9-2.12.1-1.51.71.5-0.1-1.81.9-0.51.21.0
Food consumed during 24 hour testing period0.60.91.8-1.00.70.8-0.81.3-1.2-1.31.30.5-1.3-0.5-0.2-0.00.0-1.2-0.11.21.30.4-0.41.1-0.9-1.1
Glucose0.71.22.1-1.11.31.4-1.40.9-1.1-0.80.71.1-0.6-1.1-1.5-1.41.4-0.81.20.7-0.1-1.31.4-0.51.10.7
Heart weight3.25.08.8-2.82.62.8-2.73.0-2.8-2.92.92.4-2.9-2.4-2.4-1.81.8-2.41.62.22.0-0.70.71.3-0.0-0.6
Delay discount hyperbolic model param0.91.02.6-0.81.20.8-0.90.2-0.5-0.10.21.3-0.1-1.3-1.2-1.31.30.41.5-0.4-1.0-1.31.1-1.11.60.8
Intermittent access intake day 1-15 change1.02.05.3-1.11.71.5-1.60.5-0.8-0.30.31.6-0.2-1.6-1.6-1.81.8-0.12.30.1-1.0-2.01.8-1.51.71.3
Intermittent access intake escalation0.71.53.9-1.01.51.4-1.40.5-0.7-0.40.41.4-0.3-1.4-1.4-1.61.6-0.22.00.1-0.7-1.71.5-1.21.51.1
Intermittent access intake escalation 21.31.43.0-1.21.51.7-1.71.0-0.9-0.90.91.4-0.8-1.4-1.4-1.51.5-0.81.70.70.0-1.41.3-0.50.80.7
Intermitt. access day 1 inactive lever presses0.10.31.00.0-0.2-0.80.8-0.40.50.3-0.10.50.0-0.60.80.6-0.61.0-0.0-1.00.10.6-0.90.1-0.6-0.0
Intermitt. access day 15 inactive lever presses0.10.20.8-0.70.5-0.10.10.4-0.5-0.40.70.9-0.7-0.90.20.1-0.10.30.2-0.30.30.4-0.60.2-0.6-0.6
Intermitt. access escalation Index0.20.20.50.4-0.4-0.60.6-0.70.30.7-0.7-0.50.70.50.30.1-0.10.2-0.2-0.2-0.7-0.20.2-0.70.60.3
Intermittent access day 1 total infusions0.61.03.9-0.1-0.5-0.20.20.7-0.2-0.80.9-0.2-1.00.10.40.9-0.9-0.6-1.20.61.61.5-1.42.0-1.8-1.3
Intermittent access day 15 total infusions0.71.01.7-1.21.21.3-1.31.2-1.1-1.21.21.1-1.2-1.1-1.1-0.90.9-1.00.91.00.7-0.50.50.4-0.1-0.0
Intermittent access terminal intake (last 3 days)1.51.93.8-1.61.32.0-1.91.8-1.6-1.71.51.2-1.5-1.2-1.6-1.31.3-1.80.81.81.2-0.60.81.0-0.2-0.1
Intermittent access total infusions0.50.61.1-0.90.71.0-1.01.0-0.8-1.01.00.8-1.0-0.8-1.0-0.60.6-0.90.40.80.9-0.20.20.8-0.5-0.0
Intermittent access day 1 locomotion1.31.74.4-1.20.60.4-0.31.6-1.3-1.71.80.8-1.9-0.9-0.20.5-0.5-1.0-0.51.02.01.3-1.31.9-2.1-1.9
Intermittent access day 15 total locomotion0.40.72.2-0.40.90.6-0.6-0.1-0.00.2-0.11.10.2-1.1-1.0-1.01.00.71.5-0.7-1.0-1.21.0-1.00.91.1
Intermittent access total locomotion0.40.41.2-0.80.90.7-0.70.7-0.6-0.70.81.1-0.8-1.1-0.8-0.60.6-0.10.80.10.3-0.40.30.1-0.30.1
Intermittent access standard deviation0.51.11.9-1.21.31.3-1.40.9-0.8-0.80.81.4-0.7-1.4-1.2-1.31.3-0.51.40.40.1-1.11.1-0.30.40.7
Left kidney weight1.15.210.2-2.53.12.7-2.81.7-1.9-1.61.63.1-1.4-3.0-3.2-2.92.9-0.63.20.3-0.3-2.52.3-1.31.81.5
Right kidney weight0.73.36.5-1.72.22.1-2.10.9-1.2-0.80.72.2-0.5-2.2-2.5-2.42.4-0.22.60.1-0.9-2.42.3-1.51.91.9
Cocaine induced anxiety1.52.15.20.5-1.2-1.21.20.10.2-0.30.4-1.4-0.51.41.51.9-1.9-0.8-2.00.91.52.2-2.21.8-2.1-2.3
Post-drug Anxiety1.31.44.5-0.3-0.3-0.40.50.7-0.4-0.91.1-0.6-1.10.61.11.2-1.2-1.1-1.21.21.61.8-1.81.6-1.6-2.1
Baseline Anxiety1.41.63.4-1.31.71.5-1.50.8-0.9-0.70.71.6-0.6-1.6-1.6-1.71.7-0.31.80.2-0.5-1.61.5-1.01.41.1
Tail length2.28.414.3-3.83.73.6-3.63.3-3.8-3.23.13.2-2.9-3.1-3.3-3.23.2-3.02.72.71.5-2.12.20.30.6-0.0
Length with tail2.711.719.4-4.44.24.2-4.24.2-4.2-4.03.93.6-3.7-3.5-3.8-3.53.5-3.82.93.62.3-2.12.21.10.2-0.1
Length without tail0.72.13.9-1.81.71.8-1.81.9-1.6-1.91.81.3-1.7-1.2-1.6-1.31.3-2.00.91.91.4-0.70.80.9-0.3-0.0
Times rat made contact with spout1.92.14.41.7-1.1-1.31.3-2.11.92.1-2.0-0.92.00.90.80.4-0.42.00.1-2.0-2.1-0.40.2-1.81.01.3
Lifetime Intake0.91.12.1-1.21.11.4-1.41.3-1.1-1.31.21.2-1.2-1.2-1.4-1.01.0-1.00.80.90.8-0.50.60.7-0.10.2
Liver weight, left1.62.67.4-0.51.41.2-1.2-0.20.10.4-0.41.40.6-1.4-2.0-1.91.90.72.4-0.8-1.9-2.42.2-2.22.72.5
Liver weight, right1.93.48.91.2-0.2-0.60.6-2.11.82.2-2.2-0.02.30.0-0.4-0.70.72.41.3-2.4-3.0-1.81.6-2.92.62.8
Locomotor activity8.713.623.9-4.74.24.5-4.44.8-4.9-4.84.63.5-4.5-3.4-3.0-3.33.3-4.62.34.53.2-1.41.62.2-0.5-1.3
Locomotor testing distance5.39.617.0-3.93.53.7-3.74.1-4.1-4.13.92.9-3.9-2.8-2.6-2.62.6-3.91.93.82.7-1.11.21.9-0.6-1.3
Locomotor testing rearing4.59.014.9-3.73.43.9-3.83.9-3.8-3.83.73.1-3.6-3.0-3.0-2.62.6-3.52.23.42.3-1.21.31.7-0.1-1.0
Locomotion in novel chamber0.10.10.50.4-0.30.3-0.3-0.10.20.1-0.2-0.70.20.70.50.1-0.1-0.6-0.20.60.1-0.00.10.20.20.1
Locomotion in novel chamber post-restriction0.91.54.70.4-1.0-1.11.20.10.1-0.30.5-0.6-0.60.51.01.8-1.80.2-1.6-0.01.22.1-2.21.9-1.5-1.7
Fecal boli incidents, locomotor time 11.62.34.7-2.01.81.7-1.71.6-2.1-1.51.31.2-1.2-1.2-1.4-1.81.8-2.21.22.10.6-1.31.5-0.21.0-0.1
Change in fecal boli incidents, locomotor task0.90.92.31.1-0.8-0.90.9-1.21.51.2-1.2-0.71.20.70.60.6-0.61.5-0.2-1.5-1.10.0-0.2-0.80.60.8
Time >=10cm from walls, locomotor time 10.80.82.4-1.31.11.1-1.10.8-1.0-0.80.81.5-0.7-1.5-1.2-1.11.1-0.31.00.20.2-0.70.60.00.30.1
Bouts of movement, locomotor time 10.50.52.10.1-0.7-0.30.40.3-0.3-0.30.1-0.9-0.20.90.70.7-0.7-0.7-1.50.71.10.8-0.40.9-1.3-0.3
Total resting periods, locomotor time 10.40.41.80.1-0.7-0.10.20.3-0.4-0.30.0-0.9-0.10.90.50.4-0.4-0.9-1.40.91.00.6-0.10.8-1.3-0.1
Rest time, locomotor task time 10.81.13.30.0-0.9-0.20.30.6-0.6-0.60.3-1.3-0.41.30.90.8-0.8-1.5-1.81.71.31.1-0.61.4-1.3-1.2
Distance moved, locomotor task time 11.11.64.4-0.21.00.3-0.4-0.70.30.8-0.51.60.7-1.6-1.1-1.11.11.72.1-1.8-1.9-1.51.1-2.01.41.4
Vertical activity count, locomotor time 10.71.74.2-0.10.90.7-0.8-0.50.30.7-0.61.20.7-1.2-1.4-1.51.51.12.0-1.1-1.8-1.91.6-1.82.02.0
Time >=10cm from walls, locomotor time 20.10.10.7-0.50.20.2-0.20.1-0.4-0.10.30.8-0.3-0.8-0.1-0.10.10.20.3-0.30.10.1-0.20.1-0.4-0.3
Bouts of movement, locomotor time 20.10.20.50.4-0.4-0.50.5-0.30.50.3-0.2-0.40.20.40.50.7-0.70.2-0.3-0.20.20.4-0.50.1-0.2-0.4
Total resting periods, locomotor time 20.30.61.11.0-0.9-0.90.9-0.91.10.9-0.8-0.80.80.80.90.8-0.80.8-0.5-0.8-0.20.4-0.5-0.2-0.1-0.0
Rest time, locomotor task time 20.40.52.20.9-1.0-0.70.7-0.70.60.7-1.0-1.51.01.50.70.2-0.20.1-0.90.0-0.40.00.3-0.20.10.1
Distance moved, locomotor task time 20.60.72.7-0.91.01.0-1.00.7-0.9-0.60.71.6-0.7-1.6-1.1-0.70.7-0.11.10.00.0-0.60.4-0.10.50.3
Vertical activity count, locomotor time 20.40.51.7-0.60.80.6-0.60.3-0.3-0.20.31.3-0.3-1.3-1.0-0.80.80.31.1-0.3-0.4-0.70.6-0.61.10.7
Light reinforcement 10.20.41.2-0.30.60.7-0.70.1-0.4-0.1-0.10.50.1-0.5-0.5-0.90.9-0.30.80.3-0.5-1.01.1-0.80.81.0
Light reinforcement 21.21.84.20.9-1.4-1.41.4-0.40.60.3-0.1-1.10.01.11.91.9-1.90.3-1.7-0.21.22.0-2.01.3-1.9-1.8
Bone: marrow area2.04.310.7-2.31.72.3-2.22.8-2.7-2.82.61.1-2.6-1.0-1.4-1.11.1-3.30.23.22.4-0.00.41.9-1.7-1.7
Bone: maximum diameter4.99.218.9-3.52.53.1-3.04.2-3.9-4.24.22.0-4.2-1.9-1.7-1.21.2-4.30.44.33.90.5-0.23.4-2.2-2.7
Bone: maximum force1.52.64.3-2.01.82.1-2.01.9-2.0-1.81.71.6-1.6-1.5-1.8-1.71.7-2.11.22.00.9-1.11.30.50.30.0
Bone: maximum moment1.73.05.5-2.21.92.2-2.22.1-2.2-2.01.81.6-1.7-1.5-1.9-1.81.8-2.41.22.31.0-1.21.40.60.20.0
Mean time between licks in bursts0.51.24.2-0.10.40.4-0.5-0.4-0.10.5-0.90.21.0-0.2-1.0-1.51.5-0.00.90.0-1.3-1.82.0-1.41.72.0
Mean num. licks in bursts0.30.51.4-0.20.40.2-0.3-0.40.20.4-0.40.70.5-0.7-0.6-0.70.70.71.0-0.7-1.1-0.90.8-1.20.90.9
Cd content in liver1.01.13.0-0.10.60.3-0.3-0.60.20.7-0.70.50.8-0.5-0.9-1.31.30.61.3-0.6-1.5-1.61.6-1.61.71.7
Co content in liver2.22.64.1-1.92.02.0-2.01.5-2.0-1.41.31.6-1.1-1.5-1.9-2.02.0-1.71.61.60.2-1.71.8-0.21.00.5
Cu content in liver0.40.41.30.6-0.3-0.40.3-0.90.70.9-1.0-0.51.00.50.1-0.10.10.40.2-0.3-1.1-0.60.6-1.00.90.9
Fe content in liver0.10.20.60.5-0.5-0.20.2-0.30.20.4-0.6-0.80.60.80.3-0.10.1-0.3-0.60.3-0.2-0.20.5-0.20.30.3
K content in liver2.42.34.51.6-2.0-1.91.9-1.41.51.3-1.2-1.71.11.61.82.1-2.10.9-1.8-0.7-0.11.6-1.60.5-1.0-0.8
Mg content in liver2.22.24.11.7-1.9-2.02.0-1.61.61.6-1.5-1.51.41.51.71.9-1.91.3-1.5-1.2-0.61.3-1.30.0-0.6-0.4
Mn content in liver1.51.73.71.0-1.6-1.41.4-0.50.90.4-0.3-1.30.21.21.61.9-1.90.2-1.9-0.00.81.9-1.91.3-1.5-1.3
Na content in liver3.23.46.12.3-2.1-2.52.5-2.12.32.0-1.7-1.61.61.52.12.2-2.22.3-1.5-2.2-0.71.5-1.7-0.2-0.5-0.3
Rb content in liver1.11.22.71.3-1.1-0.90.9-1.51.51.5-1.6-1.01.60.90.60.4-0.41.3-0.3-1.2-1.5-0.30.3-1.31.01.0
Se content in liver1.92.34.61.5-2.1-1.71.7-1.01.40.9-0.9-1.60.71.51.92.1-2.10.8-2.2-0.60.42.0-1.90.9-1.5-1.0
Sr content in liver1.81.64.4-1.11.71.0-1.00.5-0.7-0.40.62.0-0.5-2.0-1.5-1.61.60.72.1-0.9-0.7-1.41.0-1.11.41.1
Zn content in liver0.50.61.50.0-0.6-0.50.60.2-0.3-0.20.3-0.5-0.30.50.81.0-1.0-0.6-1.10.70.91.1-1.01.1-1.1-1.2
Bone: minimum diameter2.24.09.4-2.41.82.3-2.32.7-2.7-2.72.51.3-2.5-1.3-1.6-1.31.3-3.10.63.02.0-0.40.71.6-0.8-1.2
Time in familiar zone, hab. session 11.21.22.3-0.91.21.4-1.40.6-0.7-0.50.41.1-0.3-1.1-1.5-1.51.5-0.51.40.4-0.4-1.41.5-0.71.21.2
Time in novel zone, hab. session 10.20.20.40.5-0.5-0.60.6-0.50.40.4-0.4-0.50.40.50.60.5-0.50.4-0.4-0.4-0.10.3-0.4-0.1-0.2-0.1
Total zone transitions, hab. session 11.31.84.50.7-1.4-1.21.3-0.20.60.00.1-1.0-0.30.91.51.9-1.90.0-1.80.01.22.1-2.11.6-1.9-1.8
Total locomotion distance, hab. session 11.42.03.41.6-1.8-1.81.8-1.21.41.1-1.1-1.61.01.51.81.9-1.91.0-1.7-0.9-0.11.5-1.50.4-0.9-0.8
Locomotion velocity, hab. session 12.23.16.91.4-2.2-1.91.9-0.71.00.6-0.5-2.00.42.02.42.5-2.50.2-2.6-0.11.02.4-2.31.6-2.0-2.0
Time in familiar zone, hab. session 20.90.92.90.30.2-0.20.1-0.90.51.0-1.00.21.1-0.2-0.4-0.70.71.10.9-1.1-1.6-1.21.1-1.71.41.5
Time in novel zone, hab. session 21.31.33.7-0.80.20.6-0.61.4-1.0-1.41.40.0-1.5-0.10.10.3-0.3-1.7-0.81.71.91.0-0.81.9-1.5-1.6
Total zone transitions, hab. session 21.82.36.70.5-1.2-1.31.30.10.4-0.30.6-0.6-0.70.61.52.1-2.10.1-1.8-0.01.72.5-2.62.1-2.3-2.2
Total locomotion distance, hab. session 21.92.55.90.9-1.7-1.51.5-0.30.60.10.0-1.2-0.21.21.92.3-2.30.2-2.2-0.11.42.4-2.41.9-2.1-2.1
Locomotion velocity, hab. session 21.92.66.30.8-1.6-1.51.5-0.20.60.00.1-1.2-0.31.11.92.3-2.30.2-2.2-0.11.52.5-2.52.0-2.2-2.3
Novel to familiar place preference ratio0.80.92.2-1.00.80.7-0.71.3-1.1-1.31.40.8-1.5-0.8-0.3-0.10.1-0.80.10.81.30.6-0.71.2-0.9-1.0
Novelty place preference1.61.73.9-1.41.01.1-1.01.8-1.6-1.81.90.9-2.0-0.9-0.5-0.20.2-1.50.11.51.80.7-0.71.7-1.3-1.4
Time in novel zone, NPP test1.21.32.9-1.31.01.0-1.01.6-1.5-1.61.70.9-1.7-0.8-0.5-0.30.3-1.40.21.31.50.4-0.41.3-0.9-1.0
Total zone transitions, NPP test0.81.14.0-0.0-0.4-0.70.70.40.2-0.50.80.2-0.9-0.30.81.4-1.40.2-0.9-0.21.41.8-2.01.6-1.7-1.7
Total locomotion distance, NPP test0.91.23.80.3-0.8-0.90.90.20.2-0.30.5-0.3-0.60.31.11.6-1.60.1-1.3-0.11.31.8-1.91.5-1.7-1.8
Locomotion velocity, NPP test0.81.13.50.1-0.6-0.80.80.20.2-0.30.6-0.2-0.70.11.01.5-1.50.1-1.1-0.21.31.7-1.91.5-1.5-1.7
Intraocular pressure0.10.20.7-0.0-0.00.5-0.50.2-0.3-0.2-0.0-0.30.10.4-0.1-0.50.5-0.8-0.20.80.2-0.40.70.10.20.0
Delta distance traveled before/after self-admin0.80.82.81.0-0.5-1.01.0-1.21.31.2-1.0-0.31.00.30.40.6-0.61.70.1-1.7-1.10.0-0.3-0.90.90.6
Delta ambulatory time before/after self-admin1.31.63.41.6-1.0-1.41.3-1.71.71.7-1.6-0.91.60.90.80.8-0.81.8-0.2-1.8-1.5-0.0-0.1-1.10.91.0
Parametrial fat weight1.94.49.7-1.82.62.2-2.20.9-1.5-0.70.52.1-0.3-2.0-2.7-2.92.9-0.53.00.4-1.4-3.13.1-2.02.52.1
Pavlov. Cond. lever latency1.41.85.50.7-0.3-0.10.1-1.30.71.4-1.8-0.61.90.6-0.5-1.01.00.70.6-0.6-2.0-1.82.1-2.01.92.3
Pavlov. Cond. magazine entry latency2.93.89.81.7-1.9-2.32.4-1.01.60.8-0.3-1.60.21.62.52.8-2.81.2-2.1-1.10.72.8-3.11.3-2.2-2.2
Pavlov. Cond. change in total contacts1.61.64.50.6-1.0-0.80.90.20.2-0.40.6-0.9-0.70.91.41.7-1.7-0.3-1.60.41.42.1-2.11.7-2.0-2.0
Pavlov. Cond. index score2.12.79.20.7-1.1-1.41.40.10.6-0.30.7-0.8-0.90.71.82.3-2.30.3-1.7-0.31.62.7-3.01.9-2.4-2.6
Pavlov. Cond. latency score1.82.28.00.4-0.8-1.11.10.40.3-0.51.0-0.5-1.10.51.52.0-2.00.1-1.4-0.11.62.5-2.81.9-2.3-2.6
Pavlov. Cond. lever contacts1.11.34.3-0.60.30.00.01.1-0.5-1.21.60.7-1.7-0.70.40.9-0.9-0.3-0.30.31.61.6-1.91.6-1.6-2.1
Pavlov. Cond. magazine entry number3.24.111.8-1.61.92.3-2.30.7-1.4-0.50.01.50.1-1.5-2.6-3.03.0-1.02.20.9-1.1-3.13.4-1.72.52.6
Pavlov. Cond. intertrial magazine entries1.61.96.4-0.40.71.3-1.3-0.1-0.30.3-0.70.60.8-0.6-1.6-1.91.9-0.11.40.1-1.4-2.32.5-1.72.12.3
Pavlov. Cond. lever-magazine prob. diff.2.02.58.60.8-1.1-1.51.5-0.10.7-0.10.5-0.8-0.70.81.82.3-2.30.5-1.6-0.41.32.6-2.91.7-2.2-2.4
Pavlov. Cond. response bias2.42.99.90.9-1.3-1.61.6-0.10.8-0.10.5-1.0-0.70.92.02.5-2.50.5-1.8-0.41.42.8-3.11.8-2.5-2.6
Pavlov. Cond. lever latency4.25.710.83.0-2.6-2.92.9-3.33.23.3-3.1-2.13.12.12.11.8-1.83.1-1.2-3.0-2.30.6-0.8-1.50.51.0
Pavlov. Cond. magazine entry latency0.30.31.00.6-0.7-0.50.6-0.20.70.1-0.0-0.4-0.00.40.41.0-1.00.4-0.7-0.30.20.9-1.00.4-0.7-0.4
Pavlov. Cond. change in total contacts2.74.48.7-2.62.22.3-2.32.9-2.8-2.92.92.1-2.9-2.0-1.9-1.41.4-2.41.02.32.2-0.20.31.5-0.6-1.1
Pavlov. Cond. index score2.12.85.9-1.91.51.9-1.92.4-2.1-2.42.41.4-2.4-1.4-1.4-0.80.8-2.20.42.11.90.10.01.5-0.8-1.0
Pavlov. Cond. latency score2.02.75.8-1.81.21.7-1.62.4-2.0-2.42.41.1-2.4-1.1-1.0-0.40.4-2.20.12.22.20.5-0.41.8-1.2-1.4
Pavlov. Cond. lever contacts3.65.09.0-2.82.62.7-2.73.0-2.9-3.02.82.2-2.8-2.2-2.2-1.81.8-2.61.42.51.8-0.80.91.0-0.1-0.7
Pavlov. Cond. magazine entry number0.60.81.61.0-0.8-1.21.2-1.31.01.2-1.2-0.91.20.91.10.5-0.51.0-0.5-1.0-0.70.2-0.2-0.50.20.1
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.10.20.0-0.0-0.0-0.20.1-0.10.00.1-0.00.1-0.30.30.10.1-0.1-0.1-0.20.2-0.10.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.72.24.8-1.71.31.7-1.72.2-1.9-2.22.11.1-2.1-1.1-1.2-0.70.7-2.00.32.01.70.10.11.3-0.7-0.9
Pavlov. Cond. response bias3.04.17.1-2.52.42.5-2.52.7-2.5-2.62.52.1-2.5-2.1-2.2-1.81.8-2.21.52.11.4-0.91.00.70.1-0.4
Time in closed arm before self-admin2.02.54.91.7-1.8-2.22.2-1.41.71.3-1.0-1.51.01.51.72.1-2.11.5-1.6-1.4-0.21.8-2.00.3-1.3-1.1
Time in closed arm after self-admin0.40.40.90.8-0.7-0.80.8-0.90.80.9-0.8-0.60.80.60.80.5-0.50.9-0.4-0.9-0.60.2-0.3-0.4-0.0-0.2
Time in open arm before self-admin0.50.51.2-0.90.61.0-1.01.0-0.9-1.00.90.5-0.9-0.5-0.7-0.50.5-1.10.21.10.8-0.20.30.60.2-0.1
Time in open arm after self-admin1.51.65.1-1.20.40.6-0.51.6-1.2-1.61.70.5-1.8-0.5-0.40.5-0.5-1.4-0.71.32.31.2-1.12.0-1.8-1.4
Bone: periosteal estimation2.96.113.4-2.92.12.7-2.73.4-3.2-3.43.21.6-3.2-1.6-1.7-1.31.3-3.70.53.62.9-0.00.32.4-1.6-1.9
Bone: periosteal perimeter2.84.89.0-2.72.22.4-2.43.0-2.8-3.03.02.0-3.0-2.0-1.8-1.31.3-2.70.92.72.3-0.10.21.9-1.1-1.4
Bone: post-yield work1.52.24.8-1.81.51.9-1.81.9-2.0-1.91.61.1-1.6-1.1-1.3-1.41.4-2.20.72.21.3-0.70.90.8-0.4-0.6
Progressive ratio test 1 active lever presses2.32.85.3-2.21.71.8-1.82.3-2.3-2.32.21.6-2.2-1.6-1.2-1.21.2-1.90.71.81.9-0.30.41.5-1.1-0.8
Progressive ratio test 1 breakpoint2.22.65.2-2.11.61.7-1.72.2-2.3-2.22.11.6-2.1-1.6-1.2-1.11.1-1.80.61.72.0-0.10.21.6-1.2-0.9
Progressive ratio test 1 inactive lever presses1.72.44.8-2.21.61.4-1.42.1-2.1-2.12.21.7-2.2-1.7-0.7-0.70.7-1.60.61.51.90.2-0.21.4-1.4-1.1
Progressive ratio test 2 active lever presses0.10.10.60.1-0.3-0.20.20.00.0-0.10.1-0.1-0.10.10.60.3-0.30.2-0.4-0.20.50.5-0.50.5-0.8-0.3
Progressive ratio test 2 breakpoint0.10.10.50.1-0.2-0.10.20.1-0.0-0.10.1-0.1-0.10.10.60.3-0.30.1-0.4-0.10.50.4-0.40.5-0.7-0.3
Progressive ratio test 2 inactive lever presses0.10.10.50.1-0.1-0.10.10.10.2-0.10.20.2-0.3-0.20.40.3-0.30.3-0.1-0.30.60.5-0.60.6-0.7-0.2
Incentive Sensitization - Responses1.82.54.52.1-1.9-1.81.8-1.92.11.8-1.7-1.61.71.51.81.6-1.61.9-1.1-1.9-0.90.9-1.0-0.5-0.10.2
Incentive Sensitization - Breakpoint1.72.24.22.1-1.8-1.71.7-1.82.11.8-1.7-1.51.61.41.71.5-1.51.9-1.0-1.8-1.00.8-0.9-0.60.00.3
Sum of active levers in priming session hrs 5-60.60.61.5-0.60.80.7-0.80.1-0.4-0.10.00.70.1-0.7-0.6-1.01.0-0.01.0-0.0-0.6-1.11.1-0.81.20.9
Progressive ratio0.61.02.61.3-1.3-0.80.8-1.41.11.4-1.6-1.41.61.40.70.5-0.50.6-0.8-0.6-0.8-0.10.3-0.70.40.8
Food seeking constrained by brief footshock0.20.31.40.6-0.7-0.50.5-0.30.40.3-0.4-1.20.41.2-0.20.5-0.5-0.4-0.80.50.10.4-0.20.3-0.3-0.1
Seeking ratio, punishment vs. effort0.20.31.0-0.50.50.0-0.00.8-0.5-0.81.00.4-1.0-0.4-0.30.1-0.1-0.50.10.50.70.5-0.60.7-0.7-0.8
Retroperitoneal fat weight1.14.713.60.11.20.2-0.3-1.50.91.7-1.61.41.8-1.5-1.6-1.81.82.52.7-2.6-3.5-2.82.5-3.73.33.3
Reaction time number correct0.40.82.6-1.11.20.6-0.60.4-0.5-0.30.51.6-0.4-1.6-0.8-1.01.00.51.4-0.7-0.4-0.80.6-0.60.90.7
Reaction time mean minus median2.97.212.93.0-3.5-3.23.2-2.12.61.9-1.8-3.51.63.52.93.6-3.61.1-3.5-0.90.63.1-3.01.3-2.1-2.0
Reaction time mean minus median AUC2.56.411.32.9-3.3-3.13.2-2.02.51.9-1.7-3.41.63.32.83.4-3.41.1-3.3-0.90.62.9-2.81.2-1.9-1.7
Reaction time num false alarms0.30.41.40.0-0.40.1-0.00.5-0.2-0.50.5-0.3-0.60.3-0.00.7-0.7-0.6-0.80.61.00.9-0.91.2-1.0-1.1
Reaction time num false alarms AUC0.20.41.20.2-0.6-0.00.10.3-0.1-0.40.3-0.4-0.40.40.10.7-0.7-0.4-0.90.50.80.9-0.81.1-0.9-1.0
Reaction time trials correct on left0.40.82.6-1.11.20.6-0.60.4-0.5-0.30.51.6-0.4-1.6-0.8-1.01.00.51.4-0.7-0.4-0.80.6-0.60.90.7
Reaction time trials on left0.30.62.1-0.91.10.5-0.50.3-0.4-0.30.41.5-0.4-1.5-0.7-0.80.80.51.3-0.7-0.3-0.70.5-0.60.80.6
Reaction time mean3.75.911.53.3-3.4-2.93.0-2.72.92.6-2.7-3.42.63.32.42.7-2.71.6-2.8-1.5-0.91.7-1.4-0.3-0.4-0.3
Reaction time mean AUC3.96.312.13.3-3.5-3.13.1-2.72.92.6-2.7-3.52.63.42.52.8-2.81.6-2.9-1.5-0.81.8-1.6-0.2-0.5-0.4
Median of all reaction times2.84.07.92.8-2.7-2.32.3-2.42.42.3-2.5-2.82.42.71.71.9-1.91.4-2.1-1.3-1.20.9-0.6-0.80.20.3
Reaction time omissions4.05.913.92.8-3.6-2.62.6-1.82.01.6-1.9-3.71.73.62.82.9-2.90.1-3.70.10.62.5-2.01.4-2.1-1.6
Reaction time false alarm rate0.40.61.60.4-0.8-0.10.10.3-0.1-0.40.3-0.9-0.30.80.10.9-0.9-0.8-1.20.91.01.0-0.81.3-1.1-1.2
Reaction time premature initiation rate2.53.56.3-2.52.32.1-2.12.4-2.4-2.42.52.0-2.5-1.9-1.5-1.61.6-2.11.32.11.6-0.50.41.0-0.1-0.9
Reaction time premature initiations2.44.38.5-2.92.82.3-2.32.6-2.6-2.52.72.7-2.6-2.6-1.8-1.91.9-1.81.91.61.5-0.80.60.80.2-0.6
Std. dev. reaction times4.07.313.93.4-3.7-3.43.4-2.63.02.5-2.5-3.72.43.72.93.3-3.31.5-3.3-1.3-0.22.4-2.30.4-1.3-1.1
Reaction time trials completed0.30.62.1-0.91.10.5-0.50.3-0.4-0.30.41.5-0.4-1.5-0.7-0.80.80.51.3-0.7-0.3-0.70.5-0.60.80.6
Reaction time trials AUC0.40.82.4-1.01.20.6-0.60.3-0.4-0.20.41.6-0.3-1.6-0.9-1.01.00.61.5-0.7-0.5-0.90.6-0.81.00.8
Run reversals in cocaine runway, females2.72.75.62.2-1.9-1.81.8-2.11.72.1-2.4-2.22.42.21.60.9-0.91.6-1.3-1.5-1.50.00.2-1.10.10.6
Run reversals in cocaine runway, males1.21.22.4-1.31.11.1-1.11.5-1.4-1.51.51.0-1.5-0.9-1.0-0.60.6-1.50.51.41.2-0.00.01.0-0.5-0.4
Latency to leave start box in cocaine runway1.82.05.21.7-1.3-1.71.7-1.91.91.9-1.7-0.81.60.81.31.2-1.22.2-0.4-2.3-1.00.5-0.8-1.10.20.5
Latency to leave start box in cocaine runway, F2.12.36.51.8-1.3-1.71.6-2.12.12.1-2.0-0.92.00.90.90.8-0.82.4-0.2-2.6-1.4-0.0-0.2-1.50.71.2
Latency to leave start box in cocaine runway, M0.40.30.90.5-0.5-0.70.7-0.60.80.6-0.3-0.30.30.30.80.8-0.80.6-0.2-0.6-0.20.7-1.0-0.1-0.4-0.4
Std. dev. time between licks in bursts0.20.21.0-0.3-0.10.0-0.00.4-0.5-0.40.3-0.3-0.30.30.20.1-0.1-1.0-0.61.00.80.2-0.00.9-0.6-0.3
Total sessions with >9 infusions1.01.32.3-1.31.41.5-1.51.3-1.1-1.31.31.5-1.3-1.5-1.3-1.11.1-0.71.20.70.6-0.70.60.40.30.2
Short access day 1 total inactive lever presses1.72.24.0-1.92.02.0-2.01.6-1.6-1.51.52.0-1.4-2.0-1.2-1.81.8-1.01.80.90.4-1.31.2-0.20.60.6
Short access day 10 total inactive lever presses0.30.62.1-0.90.5-0.30.30.7-0.6-0.71.11.0-1.1-1.00.40.5-0.5-0.10.10.00.91.0-1.30.7-1.0-1.5
Short access day 1 total infusions2.53.46.5-2.12.22.5-2.52.0-1.9-2.01.82.0-1.7-2.0-2.4-2.12.1-1.71.81.60.8-1.51.60.40.70.7
Short access day 10 total infusions0.40.51.9-1.00.90.7-0.70.7-0.7-0.70.81.3-0.8-1.4-1.0-0.60.6-0.00.8-0.10.2-0.30.20.20.00.0
Short access total infusions1.72.13.8-1.81.81.9-1.91.8-1.6-1.81.71.7-1.7-1.7-1.6-1.41.4-1.31.31.21.0-0.80.80.70.20.1
Short access day 1 locomotion1.21.53.9-1.51.91.3-1.31.1-1.1-1.11.32.0-1.2-2.0-1.4-1.41.4-0.11.8-0.10.0-1.00.8-0.40.40.4
Short access day 10 total locomotion0.30.62.40.1-0.2-0.90.9-0.00.2-0.10.40.1-0.4-0.20.51.1-1.10.7-0.5-0.70.61.2-1.40.6-1.6-1.2
Short access total locomotion0.40.52.2-0.91.00.4-0.40.7-0.5-0.71.01.5-1.0-1.5-0.7-0.20.20.40.8-0.60.30.0-0.30.1-0.4-0.5
One hour access (0.3 mA shock)0.60.71.6-0.70.91.3-1.30.8-0.5-0.70.60.9-0.6-0.9-1.2-1.11.1-0.51.00.40.3-0.90.9-0.10.60.9
Compulsive drug intake0.50.51.80.0-0.30.2-0.10.6-0.6-0.70.5-0.9-0.51.00.50.5-0.5-1.3-1.01.41.10.6-0.30.8-0.6-0.9
One hour access (shock baseline)0.20.41.4-0.00.30.5-0.5-0.10.50.1-0.10.70.1-0.8-0.9-0.70.70.61.0-0.6-0.5-0.70.5-0.30.81.2
Social response proportion0.40.52.1-0.30.50.6-0.70.1-0.3-0.0-0.2-0.00.30.1-0.4-1.01.0-0.50.60.5-0.6-1.21.4-0.81.21.0
Social responses0.40.61.8-0.80.71.0-0.91.0-1.1-1.00.80.2-0.8-0.2-0.4-0.60.6-1.30.21.30.6-0.40.60.50.2-0.3
Social time1.21.64.2-1.01.12.0-2.01.1-1.3-1.00.50.5-0.4-0.5-1.4-1.81.8-1.50.91.5-0.1-1.72.1-0.20.81.0
Soleus weight2.36.816.0-3.12.43.0-3.03.5-3.5-3.53.31.6-3.2-1.5-1.7-1.81.8-4.00.73.93.0-0.30.72.3-1.2-1.4
Bone: stiffness0.60.92.4-1.20.91.0-1.01.2-1.2-1.21.10.7-1.1-0.7-0.8-0.70.7-1.60.31.50.9-0.30.40.7-0.3-0.4
Tibialis anterior weight5.317.931.1-5.15.65.4-5.44.0-4.7-3.83.55.0-3.3-4.9-5.2-5.45.4-3.14.92.80.8-4.24.2-0.62.51.8
Time to tail flick, vehicle, before self-admin0.50.52.00.0-0.4-0.10.10.4-0.6-0.50.4-0.5-0.40.60.60.6-0.6-0.8-0.90.90.90.8-0.60.9-1.3-1.4
Time to tail flick, vehicle, after self-admin1.01.33.0-1.20.50.5-0.51.4-1.5-1.41.40.4-1.5-0.3-0.00.0-0.0-1.5-0.51.51.70.8-0.71.4-1.7-1.6
Time to tail flick, test, before self-admin1.01.01.91.3-1.3-1.31.3-1.21.41.1-1.0-0.80.90.80.61.1-1.11.3-0.8-1.3-0.40.8-0.9-0.1-0.4-0.1
Time to tail flick, test, after self-admin1.71.84.7-1.51.01.8-1.81.6-1.8-1.61.20.6-1.2-0.6-1.6-1.21.2-2.20.32.21.2-0.71.10.9-0.3-0.0
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.70.50.6-0.60.6-0.7-0.60.50.3-0.5-0.3-0.4-0.60.6-0.90.20.80.6-0.30.40.3-0.30.1
Delta time to tail flick, test, before/after SA0.90.92.7-1.10.81.2-1.21.2-1.4-1.10.90.3-0.8-0.3-0.6-0.80.8-1.60.21.60.9-0.50.80.6-0.3-0.1
Tibia length1.23.46.6-2.31.71.9-1.92.5-2.5-2.52.51.5-2.5-1.4-1.2-1.01.0-2.60.52.52.10.10.01.7-1.0-1.5
Ambulatory time before self-admin0.50.82.2-1.00.20.5-0.41.1-1.0-1.21.10.5-1.2-0.5-0.20.2-0.2-1.0-0.60.91.50.8-0.61.4-1.2-1.3
Ambulatory time after self-admin0.20.21.40.2-0.1-0.40.4-0.50.40.5-0.40.30.4-0.4-0.20.2-0.21.10.2-1.2-0.5-0.1-0.0-0.40.50.4
Bone: tissue strength0.30.31.1-0.40.30.4-0.40.0-0.30.0-0.20.20.3-0.2-0.5-0.80.8-0.40.40.4-0.5-0.91.1-0.60.80.8
Total heroin consumption1.31.52.9-1.61.71.6-1.61.4-1.4-1.31.31.7-1.3-1.6-1.2-1.41.4-0.81.30.70.4-1.00.9-0.10.30.0
Bone: trabecular number5.38.721.1-3.24.13.1-3.22.0-2.1-1.82.14.6-1.9-4.6-4.1-3.63.60.04.6-0.3-0.8-3.12.5-1.62.41.9
Bone: trabecular spacing7.29.516.54.1-4.1-3.83.8-3.53.53.4-3.5-4.13.34.03.73.3-3.32.4-3.2-2.2-1.42.0-1.8-0.5-0.7-0.1
Bone: trabecular thickness3.24.07.5-2.42.72.5-2.51.8-2.0-1.71.72.7-1.6-2.7-2.6-2.52.5-0.92.50.80.1-1.91.8-0.51.10.8
Bone: trabecular tissue density1.31.95.61.0-1.7-0.91.0-0.30.40.2-0.5-2.20.42.21.81.5-1.5-1.1-2.41.31.11.5-1.01.3-1.6-1.2
Water consumed over 24 hours0.40.51.5-0.10.70.5-0.5-0.20.30.3-0.20.70.2-0.7-0.7-0.70.70.71.2-0.7-1.0-0.90.6-1.11.11.0
Number of responses in last shaping day1.01.12.5-1.61.30.8-0.81.3-1.5-1.31.61.6-1.5-1.6-0.5-0.50.5-0.50.70.40.90.1-0.30.8-0.7-0.8