Hub : Genes

LOC134479180

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression LOC134479180 0.04 0.03 8.2e-04 0.02 0.02 0.02 0.01 4.6e-03 1.2e-03 4.2e-03 7.5e-03
2 pVTA mRNA stability LOC134479180 0.05 0.03 3.4e-03 0.01 0.02 0.02 0.01 5.4e-02 5.4e-03 1.3e-02 3.0e-02
3 pVTA gene expression LOC134479180 0.2 0.09 2.5e-14 0.17 0.18 0.16 0.19 8.7e-14 2.0e-14 1.4e-12 6.8e-15
4 IC gene expression LOC134479180 0.41 0.15 3.2e-10 0.2 0.22 0.22 0.22 7.3e-09 1.5e-09 1.5e-09 1.5e-09
5 BLA mRNA stability LOC134479180 0.24 0.11 4.2e-10 0.19 0.16 0.19 0.17 2.9e-10 4.9e-09 3.5e-10 1.3e-09
6 Adipose mRNA stability LOC134479180 0.09 0.06 4.4e-08 0.07 0.07 0.06 0.07 2.5e-08 5.2e-08 1.2e-07 8.8e-08
7 Liver mRNA stability LOC134479180 0.15 0.09 4.8e-11 0.09 0.09 0.1 0.1 7.8e-10 1.0e-09 5.8e-11 7.0e-11
8 BLA gene expression LOC134479180 0.24 0.11 1.6e-10 0.2 0.18 0.19 0.2 9.0e-11 6.6e-10 2.9e-10 1.2e-10
9 Eye mRNA stability LOC134479180 0.29 0.17 7.7e-03 0.15 0.09 0.01 0.08 2.9e-03 1.8e-02 2.0e-01 2.3e-02
10 Brain mRNA stability LOC134479180 0.46 0.15 0.0e+00 0.25 0.25 0.25 0.26 1.5e-23 1.3e-23 4.0e-23 1.1e-23
11 PL gene expression LOC134479180 0.11 0.06 5.0e-10 0.09 0.09 0.09 0.09 8.7e-10 2.5e-10 4.3e-10 5.6e-10
12 NAcc gene expression LOC134479180 0.48 0.1 0.0e+00 0.54 0.56 0.56 0.56 3.8e-97 7.4e-104 1.1e-103 2.2e-103
13 NAcc mRNA stability LOC134479180 0.31 0.11 0.0e+00 0.31 0.32 0.3 0.32 2.1e-48 1.7e-49 5.1e-46 5.2e-49
14 Brain gene expression LOC134479180 0.41 0.15 0.0e+00 0.26 0.27 0.26 0.27 1.2e-23 3.0e-25 3.0e-24 3.7e-25
15 Liver gene expression LOC134479180 0.51 0.13 0.0e+00 0.43 0.45 0.45 0.45 3.0e-52 3.5e-55 8.8e-55 1.9e-54
16 PL mRNA stability LOC134479180 0.05 0.03 4.5e-05 0.01 0.03 0.05 0.03 7.6e-03 1.7e-04 8.2e-06 1.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.20.41.00.30.1-0.8-0.8-0.8-0.9-0.3-0.8-1.0-0.8-0.4-0.3-0.1-0.80.2-0.7
Area under the delay curve2.73.23.71.91.91.81.81.81.9-1.11.81.91.71.91.81.81.8-1.81.6
BMI with tail1.34.55.8-1.8-1.8-2.3-2.2-2.3-2.41.6-2.3-2.2-2.3-2.1-2.1-2.0-2.12.0-2.3
BMI without tail2.57.69.7-2.2-2.3-3.0-2.9-3.0-2.92.1-3.0-2.7-2.9-2.8-2.7-2.6-3.02.7-3.1
Body weight0.41.85.1-0.1-0.2-1.5-1.5-1.6-1.7-0.0-1.6-1.5-1.6-1.0-0.9-0.8-1.60.9-2.3
Weight adjusted by age0.10.20.8-0.9-0.8-0.2-0.2-0.1-0.50.5-0.1-0.4-0.1-0.3-0.4-0.50.10.40.4
Bone surface1.01.84.02.01.91.11.11.11.0-2.01.00.91.01.41.51.60.9-1.50.9
Bone volume0.40.72.21.51.30.40.40.40.3-1.50.40.20.40.80.91.10.4-1.00.4
Breakpoint value in progressive ratio session0.10.20.50.70.6-0.2-0.2-0.2-0.3-0.7-0.2-0.5-0.20.30.30.4-0.0-0.4-0.5
Number of licking bursts0.00.00.1-0.3-0.2-0.10.0-0.10.10.3-0.10.0-0.1-0.2-0.2-0.2-0.10.2-0.1
Context. condit. distance diff. score0.80.91.6-1.1-1.2-1.1-1.2-0.9-1.10.9-0.9-1.2-0.9-0.9-0.9-0.8-0.70.7-0.5
Locomotion velocity, session 10.20.20.30.50.40.40.30.50.5-0.50.50.30.50.50.50.60.5-0.60.4
Locomotion distance, session 10.10.10.5-0.5-0.50.20.10.20.10.50.10.10.1-0.1-0.1-0.20.20.20.7
Locomotion velocity, session 21.41.72.50.80.91.41.41.41.4-0.91.41.41.41.31.21.21.5-1.21.6
Locomotion distance, session 20.30.40.9-0.10.00.80.80.70.80.00.70.90.80.40.40.20.7-0.21.0
Locomotion velocity, session 30.80.91.70.40.51.21.21.21.1-0.41.11.11.20.80.80.71.0-0.71.3
Locomotion distance, session 30.50.51.2-0.9-0.9-0.5-0.4-0.6-0.51.1-0.6-0.5-0.6-0.8-0.8-0.9-0.81.0-0.1
Stereotopy head waving bouts, day 31.51.82.60.80.91.51.51.61.4-1.01.61.21.61.31.31.31.6-1.31.3
Stereotopy head waving duration, day 31.51.82.50.91.01.51.41.61.3-1.01.61.31.61.41.31.31.6-1.31.2
Locomotion velocity, session 74.75.17.5-2.7-2.6-2.1-2.1-2.2-2.12.7-2.1-2.0-2.1-2.4-2.4-2.5-2.02.4-1.4
Locomotion distance, session 75.36.78.5-2.8-2.7-2.6-2.4-2.6-2.32.9-2.5-2.2-2.5-2.7-2.8-2.8-2.62.8-1.9
Stereotopy head waving bouts, day 71.01.11.31.11.01.11.11.20.9-1.11.10.81.21.11.11.21.1-1.20.7
Stereotopy head waving duration, day 72.12.63.31.41.41.71.71.81.5-1.41.81.41.81.61.61.61.7-1.61.4
Locomotion velocity, session 80.50.60.90.60.60.80.70.90.8-0.70.90.80.90.80.80.91.0-0.90.7
Locomotion distance, session 80.00.10.3-0.5-0.5-0.1-0.2-0.1-0.10.4-0.1-0.2-0.0-0.2-0.2-0.20.10.20.2
Degree of sensitization distance0.40.40.7-0.5-0.5-0.7-0.7-0.7-0.60.5-0.6-0.5-0.7-0.6-0.6-0.6-0.60.5-0.8
Degree of sensitization stereotypy0.60.61.11.11.00.70.70.70.5-1.00.70.40.70.80.90.90.7-0.90.3
Conditioned locomotion1.41.62.70.80.81.41.41.51.7-0.81.51.51.51.11.11.01.2-1.11.4
Cocaine response after cond. corrected0.40.50.7-0.8-0.8-0.6-0.7-0.7-0.70.8-0.7-0.8-0.7-0.7-0.7-0.8-0.60.8-0.5
Cocaine response after cond. not corrected1.82.12.6-1.4-1.4-1.4-1.5-1.5-1.51.4-1.5-1.6-1.5-1.5-1.4-1.4-1.41.4-1.3
Cocaine response before conditioning1.31.61.9-1.0-1.0-1.3-1.2-1.3-1.31.1-1.3-1.3-1.3-1.3-1.2-1.2-1.41.2-1.3
Saline control response0.10.20.90.1-0.0-0.5-0.4-0.4-0.40.0-0.4-0.4-0.5-0.3-0.2-0.1-0.40.1-1.0
Bone: connectivity density0.81.22.30.2-0.1-1.3-1.3-1.4-1.4-0.1-1.4-1.5-1.4-0.8-0.7-0.5-1.40.6-1.4
Bone: cortical apparent density1.72.43.2-1.8-1.8-1.6-1.6-1.6-1.51.7-1.6-1.5-1.5-1.5-1.6-1.6-1.31.5-0.9
Bone: cortical area1.82.75.12.32.31.51.61.31.4-2.21.31.51.31.71.71.81.2-1.70.9
Bone: cortical porosity2.52.73.21.81.81.71.71.61.6-1.61.61.71.71.71.71.71.4-1.61.4
Bone: cortical porosity2.52.73.41.91.81.71.81.61.6-1.61.61.71.71.71.71.61.4-1.61.3
Bone: cortical thickness0.00.00.10.30.3-0.1-0.0-0.2-0.2-0.3-0.20.0-0.20.00.00.0-0.20.0-0.3
Bone: cortical thickness0.10.10.2-0.5-0.4-0.2-0.2-0.3-0.30.4-0.3-0.2-0.3-0.3-0.3-0.4-0.20.3-0.2
Bone: cortical tissue density1.72.33.2-1.8-1.8-1.6-1.6-1.5-1.51.6-1.5-1.5-1.5-1.5-1.6-1.6-1.21.5-0.9
Condit. Reinf. active minus inactive responses0.50.51.81.31.30.50.60.40.4-1.20.40.40.40.70.80.80.2-0.7-0.3
Condit. Reinf. active-inactive response ratio0.00.00.10.30.3-0.0-0.0-0.1-0.2-0.2-0.0-0.2-0.10.00.10.1-0.1-0.0-0.2
Condit. Reinf. active responses1.31.73.92.01.91.11.20.91.0-1.81.01.10.91.31.41.40.8-1.30.0
Condit. Reinf. inactive responses0.80.91.61.31.30.91.00.81.0-1.20.81.20.81.01.01.00.7-0.90.1
Incentive salience index mean1.51.84.12.02.01.21.41.11.1-1.81.11.21.01.31.41.40.7-1.20.1
Condit. Reinf. lever presses0.50.81.51.21.20.91.00.80.9-0.90.81.00.80.80.80.70.5-0.70.2
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.10.10.10.10.20.20.10.10.1-0.0-0.0-0.1-0.00.10.2
Condit. Reinf. active-inactive response ratio0.20.20.50.20.20.50.40.50.5-0.20.50.50.50.40.30.30.5-0.30.7
Condit. Reinf. active responses0.00.00.1-0.1-0.10.10.10.10.10.20.10.00.1-0.1-0.0-0.1-0.10.10.1
Condit. Reinf. inactive responses0.40.50.8-0.6-0.6-0.7-0.7-0.7-0.80.7-0.7-0.9-0.7-0.7-0.7-0.7-0.80.7-0.8
Condit. Reinf. lever presses0.10.20.70.80.70.20.10.10.2-0.60.10.10.10.40.50.50.0-0.50.2
Condit. Reinf. lever reinforcers received0.30.40.70.80.80.60.60.60.6-0.60.60.60.60.60.70.60.4-0.60.3
Conditioned reinforcement - actives1.01.73.82.01.81.11.11.01.0-1.51.11.21.01.41.51.50.9-1.50.5
Conditioned reinforcement - inactives0.10.20.70.80.6-0.4-0.4-0.4-0.3-0.3-0.4-0.2-0.40.00.20.3-0.5-0.3-0.6
Conditioned locomotion0.10.10.30.40.40.10.20.10.2-0.40.20.60.20.20.20.20.0-0.2-0.0
Patch foraging indifference point 0 sec1.32.55.32.32.21.41.41.31.4-2.31.21.41.31.61.71.71.0-1.60.3
Patch foraging indifference point AUC3.44.97.22.72.62.32.42.12.2-2.12.22.22.22.22.32.31.7-2.21.5
Delay disc. indifference point, 0s delay0.91.01.70.90.90.80.70.90.8-1.20.80.70.91.11.11.21.3-1.21.3
Delay disc. indifference point, 16s delay3.13.44.01.81.91.91.91.92.0-1.51.92.01.81.91.91.81.9-1.81.6
Delay disc. indifference point, 2s delay0.40.50.80.90.90.70.60.60.6-0.40.60.60.50.70.80.80.5-0.70.7
Delay disc. indifference point, 24s delay4.14.65.92.42.42.02.12.22.2-1.92.12.22.02.32.32.32.1-2.31.6
Delay disc. indifference point, 4s delay0.70.71.20.40.51.01.01.01.1-0.21.01.01.00.70.70.60.9-0.61.0
Delay disc. indifference point, 8s delay0.50.61.01.01.00.80.80.80.9-0.00.81.00.60.80.80.70.5-0.70.4
Indifference point function ln k0.61.01.3-1.2-1.1-1.1-1.1-1.0-1.00.7-1.1-1.0-1.0-1.0-1.0-1.0-0.81.0-1.0
Indifference point function log k0.61.01.3-1.2-1.1-1.1-1.1-1.0-1.00.7-1.1-1.0-1.0-1.0-1.0-1.0-0.81.0-1.0
Patch foraging total patch changes 0 sec1.73.26.82.52.51.61.71.51.6-2.61.51.61.51.81.91.91.2-1.80.4
Patch foraging total patch changes 12 sec2.43.16.72.62.51.61.71.41.4-2.31.41.41.41.81.91.91.1-1.80.8
Patch foraging total patch changes 18 sec0.71.02.01.41.41.01.20.91.0-1.20.91.00.90.91.00.90.4-0.80.3
Patch foraging total patch changes 24 sec1.01.73.51.91.81.31.31.11.2-1.61.11.11.21.31.41.40.7-1.20.5
Patch foraging total patch changes 6 sec1.52.25.42.32.21.31.41.21.4-2.01.21.31.21.51.61.60.7-1.50.5
Patch foraging time to switch 0 sec10.421.329.0-5.4-5.4-4.5-4.7-4.4-4.55.2-4.4-4.6-4.4-4.8-4.9-4.8-4.14.7-2.5
Patch foraging water rate 0 sec3.26.79.53.03.12.62.72.42.5-3.12.42.52.52.72.72.72.3-2.61.4
Patch foraging water rate 12 sec0.10.10.50.70.6-0.10.0-0.10.1-0.7-0.00.0-0.00.20.20.3-0.2-0.3-0.7
Patch foraging water rate 18 sec0.81.22.71.41.40.91.00.80.9-1.70.90.90.91.21.21.21.0-1.20.6
Patch foraging water rate 24 sec0.60.81.71.21.30.80.90.80.9-1.30.80.80.70.90.90.90.6-0.80.2
Patch foraging water rate 6 sec3.85.59.02.92.92.22.42.22.1-3.02.12.12.12.52.52.52.0-2.41.1
Seeking ratio, delayed vs. immediate footshock0.40.51.10.20.40.81.00.81.0-0.10.81.00.80.50.40.20.6-0.20.7
Distance traveled before self-admin0.20.30.60.50.60.70.70.50.40.10.50.50.40.50.50.40.5-0.40.4
Distance traveled after self-admin0.10.10.5-0.4-0.4-0.3-0.3-0.5-0.40.7-0.4-0.4-0.4-0.2-0.3-0.3-0.00.20.1
Extensor digitorum longus weight0.93.45.8-0.4-0.7-2.4-2.4-2.2-2.20.5-2.2-2.3-2.2-1.5-1.4-1.1-2.21.2-2.3
Bone: elastic displacement2.02.33.1-1.2-1.3-1.6-1.6-1.6-1.71.3-1.6-1.8-1.6-1.5-1.4-1.4-1.61.4-1.4
Bone: elastic work3.03.95.2-1.3-1.4-2.0-2.0-2.3-2.31.5-2.3-2.2-2.2-1.9-1.8-1.8-2.31.9-1.9
Bone: endosteal estimation4.29.19.93.03.13.13.03.13.0-3.13.12.83.13.13.13.12.9-3.12.6
Bone: endosteal perimeter5.611.914.03.73.73.53.53.43.5-3.73.43.53.43.53.53.53.1-3.52.7
Epididymis fat weight0.82.93.5-1.7-1.8-1.8-1.9-1.8-1.91.4-1.8-1.8-1.8-1.7-1.7-1.6-1.61.6-1.2
Delta time in closed arm before/after self-admin0.20.20.40.0-0.0-0.4-0.4-0.4-0.6-0.1-0.5-0.6-0.5-0.4-0.3-0.3-0.60.4-0.6
Delta time in open arm before/after self-admin0.10.10.2-0.3-0.4-0.4-0.5-0.3-0.20.5-0.2-0.2-0.2-0.4-0.3-0.2-0.40.2-0.3
Diff in mean of infusions in LGA sessions0.00.10.5-0.2-0.10.10.00.10.20.30.00.00.00.20.10.00.4-0.10.7
Delay discount exponential model param2.62.93.5-1.7-1.8-1.8-1.7-1.8-1.90.9-1.8-1.9-1.6-1.8-1.7-1.7-1.61.7-1.5
Extinction: sum of active levers before priming1.82.05.0-0.3-0.4-1.5-1.3-1.7-1.60.3-1.7-1.7-1.6-1.2-1.1-1.1-1.81.2-2.2
Active lever presses in extinction session 60.60.61.70.40.3-0.8-0.8-0.9-1.1-0.3-1.0-1.1-1.0-0.5-0.3-0.2-1.10.3-1.3
Bone: final force0.10.10.50.30.30.30.30.30.3-0.30.20.30.30.30.20.20.2-0.20.7
Bone: final moment0.20.20.70.50.50.50.50.40.5-0.50.40.40.40.50.40.50.4-0.40.8
Food consumed during 24 hour testing period0.30.51.01.01.00.50.70.50.8-0.90.50.80.50.70.70.70.4-0.7-0.1
Glucose0.20.31.60.50.4-0.6-0.5-0.7-0.6-0.4-0.7-0.7-0.7-0.2-0.1-0.0-0.70.1-1.3
Heart weight0.20.31.31.00.90.30.40.20.5-1.10.20.20.30.50.60.60.0-0.60.3
Delay discount hyperbolic model param2.32.53.0-1.6-1.7-1.7-1.7-1.7-1.70.9-1.7-1.7-1.5-1.6-1.6-1.6-1.51.6-1.4
Intermittent access intake day 1-15 change0.51.01.6-0.3-0.5-1.2-1.2-1.3-1.20.8-1.2-1.0-1.2-0.9-0.8-0.7-1.20.7-1.2
Intermittent access intake escalation0.30.71.2-0.2-0.4-1.0-0.9-1.0-0.90.8-0.9-0.8-1.0-0.8-0.7-0.6-1.10.6-0.9
Intermittent access intake escalation 21.01.12.6-0.5-0.7-1.2-1.0-1.2-1.00.9-1.1-0.9-1.1-1.2-1.0-1.0-1.61.0-1.3
Intermitt. access day 1 inactive lever presses0.00.10.30.50.50.10.2-0.00.3-0.1-0.20.4-0.10.30.20.20.2-0.3-0.2
Intermitt. access day 15 inactive lever presses1.32.74.42.02.01.31.21.21.3-2.01.11.31.21.91.92.11.8-2.11.4
Intermitt. access escalation Index0.00.00.3-0.1-0.10.0-0.10.1-0.4-0.10.0-0.5-0.0-0.0-0.1-0.00.00.10.0
Intermittent access day 1 total infusions0.40.61.51.21.20.71.00.50.7-0.80.60.90.60.70.80.70.2-0.60.0
Intermittent access day 15 total infusions0.10.10.50.70.6-0.30.0-0.4-0.30.0-0.30.0-0.3-0.10.10.1-0.70.0-0.7
Intermittent access terminal intake (last 3 days)0.10.21.01.00.8-0.00.3-0.10.2-0.3-0.00.4-0.00.10.30.3-0.6-0.2-0.5
Intermittent access total infusions0.10.10.60.80.6-0.10.2-0.20.2-0.1-0.00.4-0.00.10.20.2-0.5-0.1-0.6
Intermittent access day 1 locomotion1.41.83.11.71.81.21.51.11.4-1.61.21.51.31.31.31.30.9-1.20.5
Intermittent access day 15 total locomotion0.20.41.3-0.2-0.3-0.8-0.6-0.8-0.60.3-0.7-0.3-0.7-0.6-0.6-0.6-0.90.6-1.1
Intermittent access total locomotion0.10.10.50.30.3-0.20.1-0.30.1-0.1-0.20.3-0.1-0.1-0.1-0.1-0.50.1-0.7
Intermittent access standard deviation0.10.10.70.80.7-0.00.00.00.2-0.30.00.3-0.00.30.40.4-0.1-0.4-0.1
Left kidney weight0.10.30.8-0.1-0.3-0.8-0.9-0.7-0.5-0.1-0.8-0.6-0.7-0.2-0.20.0-0.1-0.1-0.6
Right kidney weight0.20.81.6-0.7-0.8-1.2-1.3-1.1-1.00.5-1.1-1.1-1.0-0.8-0.8-0.6-0.70.5-0.9
Cocaine induced anxiety2.63.74.51.81.82.02.02.02.0-2.12.02.02.01.92.01.91.9-1.91.6
Post-drug Anxiety3.84.04.92.01.92.02.02.02.1-2.22.02.12.02.02.12.01.9-2.01.6
Baseline Anxiety0.70.81.2-0.8-0.8-0.9-0.9-0.9-0.91.1-0.9-0.8-0.9-0.8-0.9-0.8-0.80.8-0.6
Tail length0.10.52.20.30.2-0.8-0.7-0.9-0.6-0.1-0.9-0.5-0.8-0.5-0.4-0.4-1.00.4-1.5
Length with tail0.20.83.01.71.60.30.40.20.3-1.70.20.40.30.80.91.00.1-1.0-0.5
Length without tail1.03.36.12.42.31.61.61.51.3-2.51.51.31.62.02.02.11.6-2.11.2
Times rat made contact with spout0.70.91.4-1.2-1.1-0.9-0.9-0.9-0.81.1-0.8-0.8-0.8-0.9-1.0-1.0-0.71.0-0.7
Lifetime Intake0.10.10.60.60.4-0.20.1-0.30.00.1-0.20.3-0.2-0.10.00.0-0.60.0-0.8
Liver weight, left0.91.63.0-0.6-0.6-1.5-1.4-1.5-1.50.7-1.5-1.2-1.5-1.1-1.1-1.0-1.41.0-1.7
Liver weight, right3.25.77.0-2.1-2.2-2.6-2.6-2.6-2.61.9-2.6-2.4-2.5-2.4-2.4-2.3-2.42.2-2.3
Locomotor activity0.61.04.22.11.80.20.20.20.2-2.00.10.30.10.70.91.1-0.2-1.0-0.8
Locomotor testing distance0.30.61.80.90.6-0.8-0.8-0.8-0.8-0.9-0.9-0.7-0.8-0.3-0.10.0-1.10.0-1.4
Locomotor testing rearing1.53.06.3-0.3-0.6-2.0-1.9-2.1-2.00.7-2.1-1.9-2.1-1.6-1.4-1.3-2.51.4-2.0
Locomotion in novel chamber1.31.62.9-1.5-1.5-1.1-1.1-1.1-1.01.7-1.2-0.7-1.2-1.4-1.4-1.5-1.41.5-0.7
Locomotion in novel chamber post-restriction0.71.11.90.60.81.21.21.21.3-0.21.21.41.11.00.90.81.1-0.81.2
Fecal boli incidents, locomotor time 10.91.42.2-0.5-0.6-1.4-1.5-1.4-1.40.1-1.4-1.5-1.3-1.0-1.0-0.9-1.30.9-1.4
Change in fecal boli incidents, locomotor task0.10.10.2-0.2-0.2-0.2-0.2-0.3-0.30.4-0.2-0.3-0.3-0.2-0.2-0.1-0.10.1-0.2
Time >=10cm from walls, locomotor time 10.20.20.40.60.60.40.60.40.6-0.60.50.40.50.40.50.50.3-0.50.1
Bouts of movement, locomotor time 11.72.03.41.61.51.21.01.11.2-1.81.11.21.11.51.61.61.5-1.71.2
Total resting periods, locomotor time 12.32.53.71.71.71.41.31.31.5-1.81.41.41.41.71.81.81.7-1.91.4
Rest time, locomotor task time 13.74.65.52.12.12.02.02.12.1-2.12.22.12.12.32.32.32.3-2.31.9
Distance moved, locomotor task time 11.42.12.6-1.4-1.5-1.4-1.3-1.3-1.31.2-1.4-1.4-1.3-1.6-1.5-1.6-1.61.6-1.5
Vertical activity count, locomotor time 11.33.03.6-1.5-1.6-1.7-1.7-1.8-1.71.6-1.9-1.7-1.8-1.8-1.7-1.7-1.91.7-1.7
Time >=10cm from walls, locomotor time 20.10.10.50.40.3-0.3-0.1-0.4-0.3-0.4-0.3-0.2-0.2-0.2-0.1-0.1-0.70.2-0.7
Bouts of movement, locomotor time 20.30.50.60.70.80.70.70.60.7-0.30.60.70.60.80.70.70.7-0.70.7
Total resting periods, locomotor time 20.20.30.40.40.50.50.60.50.6-0.20.50.60.50.60.50.50.6-0.50.5
Rest time, locomotor task time 20.00.00.1-0.1-0.1-0.1-0.2-0.10.00.2-0.10.1-0.10.10.00.10.2-0.1-0.1
Distance moved, locomotor task time 20.10.10.40.50.40.30.40.40.2-0.70.40.20.40.20.30.3-0.0-0.30.3
Vertical activity count, locomotor time 20.00.00.1-0.0-0.10.10.00.0-0.1-0.00.0-0.10.1-0.0-0.00.0-0.10.00.3
Light reinforcement 10.51.22.0-0.7-0.7-1.2-1.1-1.2-1.30.8-1.3-1.2-1.2-1.1-1.1-1.0-1.41.1-1.1
Light reinforcement 21.52.33.11.11.31.71.81.61.6-1.21.61.71.61.51.41.31.6-1.31.5
Bone: marrow area4.39.310.13.13.13.13.03.13.0-3.23.12.93.13.13.13.12.9-3.12.6
Bone: maximum diameter6.812.716.74.14.13.63.63.43.4-4.13.33.53.43.73.73.73.2-3.62.6
Bone: maximum force0.71.31.71.21.21.11.11.11.1-1.21.11.01.11.11.11.11.0-1.11.3
Bone: maximum moment0.91.72.01.41.41.31.31.31.2-1.41.31.21.21.31.31.31.2-1.31.4
Mean time between licks in bursts0.00.10.30.1-0.00.0-0.10.20.3-0.30.20.10.30.20.30.40.4-0.50.4
Mean num. licks in bursts0.20.20.4-0.4-0.4-0.5-0.6-0.5-0.60.3-0.5-0.6-0.5-0.4-0.4-0.4-0.50.4-0.5
Cd content in liver1.11.21.9-0.7-0.7-1.2-1.2-1.2-1.30.7-1.3-1.3-1.3-1.0-1.0-1.0-1.21.0-1.4
Co content in liver0.40.50.8-0.4-0.4-0.8-0.7-0.8-0.80.5-0.8-0.7-0.8-0.7-0.6-0.6-0.90.7-0.7
Cu content in liver0.50.61.2-1.1-1.0-0.6-0.6-0.6-0.71.1-0.6-0.6-0.6-0.8-0.9-0.9-0.70.9-0.2
Fe content in liver0.91.01.9-1.4-1.4-1.0-1.0-0.9-0.91.3-0.8-0.9-0.8-1.1-1.1-1.1-0.81.0-0.3
K content in liver1.31.33.9-0.20.01.31.41.31.50.21.41.51.40.70.50.31.2-0.42.0
Mg content in liver0.60.62.3-0.7-0.50.80.80.90.90.60.90.90.90.30.1-0.00.8-0.01.5
Mn content in liver4.04.55.91.41.52.32.32.42.4-1.52.42.42.42.02.01.92.3-1.92.2
Na content in liver1.21.33.5-1.8-1.7-0.8-0.7-0.8-0.71.9-0.7-0.6-0.7-1.2-1.3-1.5-0.81.4-0.2
Rb content in liver0.20.20.9-0.9-0.80.0-0.00.10.00.90.10.00.1-0.3-0.4-0.50.10.40.7
Se content in liver0.30.31.3-1.1-0.9-0.00.1-0.0-0.11.1-0.00.0-0.0-0.5-0.6-0.8-0.20.80.4
Sr content in liver0.50.40.7-0.3-0.4-0.7-0.7-0.8-0.70.4-0.8-0.7-0.8-0.6-0.6-0.6-0.80.6-0.8
Zn content in liver0.10.10.30.10.20.40.50.30.20.00.20.30.20.10.1-0.00.00.10.4
Bone: minimum diameter1.93.55.62.42.31.81.91.71.7-2.31.71.61.71.92.02.01.5-1.91.3
Time in familiar zone, hab. session 11.31.31.5-0.9-1.0-1.2-1.2-1.2-1.21.0-1.2-1.1-1.2-1.1-1.1-1.1-1.21.1-1.0
Time in novel zone, hab. session 11.01.01.20.90.90.90.91.01.1-1.01.00.91.01.01.01.11.0-1.10.8
Total zone transitions, hab. session 11.31.82.70.70.81.61.51.61.7-0.81.51.61.51.31.21.11.5-1.11.5
Total locomotion distance, hab. session 10.10.20.5-0.7-0.60.30.20.40.50.60.40.50.4-0.0-0.1-0.20.40.20.6
Locomotion velocity, hab. session 10.50.71.30.00.21.11.01.11.1-0.11.11.11.10.60.50.41.0-0.41.1
Time in familiar zone, hab. session 22.72.93.5-1.8-1.8-1.8-1.9-1.7-1.71.8-1.7-1.6-1.6-1.7-1.8-1.7-1.61.6-1.3
Time in novel zone, hab. session 23.03.14.22.12.01.71.81.61.7-2.01.61.61.61.81.91.91.6-1.81.1
Total zone transitions, hab. session 23.03.95.41.21.42.32.22.32.2-1.22.32.22.31.91.81.62.2-1.72.3
Total locomotion distance, hab. session 21.82.43.70.81.01.81.71.81.6-0.91.81.71.81.51.41.31.8-1.31.9
Locomotion velocity, hab. session 22.43.24.71.01.22.12.02.11.9-1.12.02.02.01.71.61.52.0-1.42.2
Novel to familiar place preference ratio0.91.01.61.31.31.01.00.90.9-1.20.80.90.81.11.11.10.8-1.00.7
Novelty place preference1.92.03.31.81.81.41.41.21.3-1.71.21.31.21.51.51.51.2-1.50.8
Time in novel zone, NPP test1.31.42.61.61.61.11.11.01.0-1.50.91.00.91.31.31.30.9-1.30.5
Total zone transitions, NPP test0.81.21.70.60.81.31.31.31.2-0.71.31.21.21.01.00.91.2-0.81.2
Total locomotion distance, NPP test1.01.42.00.60.81.41.31.41.3-0.71.41.41.41.11.00.91.3-0.91.3
Locomotion velocity, NPP test0.70.91.40.50.61.21.11.21.1-0.51.21.21.10.90.80.71.1-0.71.1
Intraocular pressure0.40.61.3-0.3-0.4-1.0-0.9-1.0-1.00.3-1.0-0.9-1.0-0.7-0.6-0.5-0.90.5-1.1
Delta distance traveled before/after self-admin0.10.20.3-0.4-0.4-0.4-0.5-0.5-0.50.4-0.5-0.5-0.4-0.3-0.3-0.3-0.20.30.2
Delta ambulatory time before/after self-admin0.20.30.6-0.8-0.8-0.5-0.6-0.5-0.60.6-0.5-0.6-0.5-0.5-0.5-0.5-0.20.50.1
Parametrial fat weight5.813.716.5-3.0-3.2-3.9-4.1-3.9-4.12.9-4.0-4.0-4.0-3.7-3.5-3.4-4.03.4-3.6
Pavlov. Cond. lever latency0.60.81.2-0.9-1.0-1.0-1.1-0.9-0.90.8-0.9-0.9-0.9-0.9-0.8-0.7-0.70.7-0.7
Pavlov. Cond. magazine entry latency0.10.10.2-0.4-0.30.30.30.20.10.50.20.30.2-0.1-0.2-0.30.00.40.5
Pavlov. Cond. change in total contacts0.70.81.10.70.81.00.91.00.9-0.81.00.91.00.90.90.81.0-0.80.8
Pavlov. Cond. index score0.30.40.90.30.50.90.90.80.8-0.30.80.90.80.60.50.30.6-0.30.8
Pavlov. Cond. latency score0.40.61.10.50.61.01.00.90.9-0.40.90.90.90.70.60.50.7-0.40.8
Pavlov. Cond. lever contacts0.10.10.30.40.50.50.50.40.3-0.30.40.30.30.30.30.20.1-0.10.3
Pavlov. Cond. magazine entry number0.20.30.8-0.0-0.2-0.8-0.8-0.7-0.70.0-0.7-0.8-0.7-0.4-0.3-0.1-0.50.1-0.9
Pavlov. Cond. intertrial magazine entries1.01.22.2-0.7-0.9-1.3-1.3-1.2-1.20.7-1.2-1.5-1.2-1.0-0.9-0.8-1.10.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.30.60.20.40.80.80.70.7-0.20.70.70.70.40.40.20.5-0.20.7
Pavlov. Cond. response bias0.30.40.90.30.40.80.80.70.7-0.20.70.90.70.50.40.30.5-0.21.0
Pavlov. Cond. lever latency0.81.12.4-1.5-1.3-0.9-0.8-0.9-1.01.3-0.9-1.0-0.8-1.1-1.2-1.3-0.71.3-0.6
Pavlov. Cond. magazine entry latency0.00.10.20.20.20.30.30.20.3-0.00.20.40.20.20.20.20.2-0.20.3
Pavlov. Cond. change in total contacts0.50.92.51.61.40.70.70.60.8-1.30.60.70.60.91.11.20.4-1.10.2
Pavlov. Cond. index score0.50.61.61.31.10.60.70.60.7-1.00.60.80.60.80.90.90.4-0.90.3
Pavlov. Cond. latency score0.70.92.01.41.30.80.90.81.0-1.10.81.00.81.01.11.10.6-1.10.4
Pavlov. Cond. lever contacts0.50.71.71.31.10.60.60.60.7-1.10.60.70.60.91.01.10.5-1.10.5
Pavlov. Cond. magazine entry number0.91.11.6-1.3-1.2-1.0-1.0-1.0-1.11.1-1.0-1.1-1.0-1.1-1.1-1.2-0.91.2-0.8
Pavlov. Cond. intertrial magazine entries0.00.10.3-0.3-0.4-0.1-0.2-0.0-0.20.30.0-0.40.0-0.1-0.1-0.10.10.10.5
Pavlov. Cond. lever-magazine prob. diff.0.60.81.81.31.20.70.70.60.8-1.00.70.90.60.91.01.00.5-1.00.3
Pavlov. Cond. response bias0.40.51.21.10.90.50.50.50.6-0.90.50.60.50.70.80.90.4-0.90.4
Time in closed arm before self-admin0.30.40.9-1.0-0.8-0.2-0.1-0.4-0.30.9-0.4-0.2-0.4-0.6-0.7-0.9-0.40.9-0.2
Time in closed arm after self-admin0.40.40.8-0.7-0.6-0.4-0.3-0.6-0.60.7-0.6-0.5-0.6-0.6-0.7-0.8-0.60.9-0.2
Time in open arm before self-admin0.40.41.10.80.80.60.60.60.4-1.00.50.30.50.70.70.80.5-0.60.7
Time in open arm after self-admin0.30.30.70.40.30.50.50.60.8-0.20.70.80.70.40.50.50.4-0.50.6
Bone: periosteal estimation5.010.513.23.53.63.33.33.23.1-3.63.13.13.13.33.33.33.0-3.32.5
Bone: periosteal perimeter3.56.08.42.92.92.42.52.32.3-2.82.22.42.32.52.52.52.1-2.51.7
Bone: post-yield work1.62.42.91.51.51.51.51.71.6-1.51.71.51.61.51.61.61.5-1.61.4
Progressive ratio test 1 active lever presses0.81.02.61.61.50.70.90.70.9-1.30.81.00.81.01.11.20.5-1.10.0
Progressive ratio test 1 breakpoint1.01.23.01.71.60.81.00.81.0-1.40.81.00.91.11.21.30.6-1.20.1
Progressive ratio test 1 inactive lever presses0.50.72.01.41.30.50.80.50.8-1.10.50.80.60.70.90.90.2-0.8-0.1
Progressive ratio test 2 active lever presses0.10.10.40.50.50.40.50.30.50.10.40.60.30.20.30.3-0.0-0.2-0.1
Progressive ratio test 2 breakpoint0.10.10.30.50.40.30.50.30.40.20.40.60.30.20.30.2-0.1-0.2-0.1
Progressive ratio test 2 inactive lever presses0.30.51.41.21.00.50.60.40.6-0.40.40.80.40.70.80.80.2-0.80.3
Incentive Sensitization - Responses0.40.62.8-1.1-1.0-0.3-0.1-0.3-0.21.7-0.2-0.1-0.3-0.8-0.8-1.0-0.71.0-0.2
Incentive Sensitization - Breakpoint0.50.72.9-1.1-1.1-0.4-0.2-0.4-0.31.7-0.3-0.2-0.5-0.9-0.9-1.1-0.81.1-0.3
Sum of active levers in priming session hrs 5-60.50.50.90.20.0-0.7-0.8-1.0-0.9-0.6-0.9-0.9-0.8-0.4-0.3-0.2-0.80.3-0.9
Progressive ratio0.60.92.60.10.10.90.61.21.0-0.31.20.91.10.90.90.91.6-1.11.2
Food seeking constrained by brief footshock0.70.91.50.60.60.90.91.10.9-0.51.10.91.11.00.91.01.2-1.00.8
Seeking ratio, punishment vs. effort0.10.20.50.10.1-0.3-0.2-0.5-0.40.1-0.4-0.5-0.4-0.4-0.3-0.3-0.70.4-0.5
Retroperitoneal fat weight4.318.220.5-4.1-4.2-4.4-4.5-4.4-4.53.7-4.4-4.4-4.4-4.3-4.3-4.2-4.34.2-3.7
Reaction time number correct0.50.91.3-0.7-0.8-1.0-0.9-1.0-1.00.8-1.1-1.1-1.0-1.0-0.9-0.9-1.21.0-0.8
Reaction time mean minus median0.30.83.6-0.4-0.21.11.01.01.00.41.01.01.00.50.40.21.0-0.21.9
Reaction time mean minus median AUC0.20.62.4-0.3-0.10.90.80.90.90.40.80.90.90.50.40.30.9-0.31.6
Reaction time num false alarms0.70.91.51.00.90.90.71.10.7-1.20.90.91.01.01.01.01.0-1.10.7
Reaction time num false alarms AUC0.81.21.91.11.01.10.81.30.9-1.41.11.11.21.11.21.21.2-1.20.9
Reaction time trials correct on left0.50.91.3-0.7-0.8-1.0-0.9-1.0-1.00.8-1.1-1.1-1.0-1.0-0.9-0.9-1.21.0-0.8
Reaction time trials on left0.40.71.1-0.6-0.7-0.9-0.8-0.9-0.90.7-0.9-1.0-0.9-0.9-0.8-0.8-1.00.9-0.7
Reaction time mean0.30.51.2-1.1-1.1-0.5-0.5-0.4-0.60.9-0.4-0.6-0.4-0.7-0.7-0.7-0.40.70.4
Reaction time mean AUC0.50.81.7-1.3-1.3-0.7-0.8-0.7-0.81.2-0.7-0.8-0.7-0.9-0.9-1.0-0.61.00.1
Median of all reaction times0.60.91.5-1.1-1.2-0.9-1.0-0.8-1.11.0-0.8-1.0-0.8-1.0-0.9-0.9-0.80.9-0.2
Reaction time omissions1.82.75.40.80.91.81.51.91.6-0.91.91.71.91.61.51.52.1-1.52.3
Reaction time false alarm rate1.31.82.61.31.21.31.01.51.1-1.61.31.31.41.41.41.51.5-1.51.0
Reaction time premature initiation rate0.50.71.41.21.10.80.90.90.8-1.10.80.80.80.80.90.90.5-0.80.2
Reaction time premature initiations0.10.20.70.80.70.30.50.40.3-0.60.30.30.40.30.40.4-0.1-0.3-0.1
Std. dev. reaction times0.30.52.7-0.4-0.30.80.70.80.70.30.80.70.80.40.30.20.9-0.21.6
Reaction time trials completed0.40.71.1-0.6-0.7-0.9-0.8-0.9-0.90.7-0.9-1.0-0.9-0.9-0.8-0.8-1.00.9-0.7
Reaction time trials AUC0.51.01.4-0.7-0.8-1.0-1.0-1.1-1.00.8-1.1-1.1-1.0-1.0-1.0-1.0-1.21.0-0.9
Run reversals in cocaine runway, females1.61.63.30.30.51.31.21.51.5-1.11.51.31.51.21.01.01.8-1.11.4
Run reversals in cocaine runway, males0.10.10.30.10.1-0.1-0.0-0.2-0.3-0.1-0.3-0.3-0.2-0.2-0.2-0.2-0.50.3-0.3
Latency to leave start box in cocaine runway0.20.20.5-0.7-0.7-0.4-0.4-0.3-0.30.5-0.4-0.3-0.3-0.5-0.5-0.5-0.20.4-0.1
Latency to leave start box in cocaine runway, F0.20.20.7-0.8-0.8-0.3-0.4-0.2-0.30.4-0.3-0.4-0.2-0.4-0.4-0.40.00.30.2
Latency to leave start box in cocaine runway, M0.60.50.8-0.6-0.6-0.7-0.7-0.7-0.60.9-0.8-0.4-0.8-0.8-0.8-0.8-0.90.8-0.8
Std. dev. time between licks in bursts0.20.20.4-0.5-0.6-0.4-0.4-0.4-0.40.6-0.5-0.4-0.4-0.5-0.5-0.5-0.60.50.2
Total sessions with >9 infusions0.10.10.30.30.2-0.3-0.2-0.3-0.10.0-0.30.1-0.2-0.2-0.1-0.1-0.50.1-0.6
Short access day 1 total inactive lever presses3.04.07.5-0.8-1.1-2.4-2.0-2.4-2.01.3-2.3-2.1-2.1-2.0-1.8-1.6-2.71.7-2.5
Short access day 10 total inactive lever presses0.00.10.50.70.70.20.1-0.00.0-0.6-0.1-0.10.00.40.40.40.0-0.30.1
Short access day 1 total infusions0.70.92.4-0.0-0.3-1.3-1.1-1.3-1.10.2-1.1-1.0-1.0-0.9-0.7-0.6-1.40.6-1.5
Short access day 10 total infusions0.00.00.10.20.2-0.10.1-0.2-0.00.1-0.20.1-0.10.00.00.0-0.10.0-0.3
Short access total infusions0.50.71.6-0.2-0.4-0.9-0.7-1.1-0.60.7-0.9-0.5-0.8-0.8-0.7-0.7-1.20.7-1.3
Short access day 1 locomotion0.40.50.8-0.3-0.4-0.9-0.8-0.9-0.80.6-0.9-0.6-0.8-0.7-0.6-0.5-0.90.6-0.9
Short access day 10 total locomotion0.00.10.1-0.1-0.1-0.2-0.2-0.3-0.20.1-0.3-0.0-0.1-0.2-0.3-0.3-0.30.3-0.3
Short access total locomotion0.10.10.30.0-0.0-0.4-0.2-0.4-0.30.1-0.4-0.1-0.3-0.3-0.3-0.3-0.50.3-0.5
One hour access (0.3 mA shock)0.40.41.81.41.20.30.30.20.2-0.80.30.50.20.60.80.80.1-0.7-0.4
Compulsive drug intake2.73.34.81.41.51.81.42.01.6-1.81.91.41.91.91.91.92.2-2.02.0
One hour access (shock baseline)0.40.72.0-0.1-0.2-0.8-0.6-1.1-0.80.7-0.9-0.4-1.0-0.8-0.6-0.7-1.30.8-1.4
Social response proportion0.50.51.00.80.80.60.60.70.5-1.00.70.50.70.80.80.80.7-0.80.5
Social responses0.40.61.11.11.00.70.70.70.5-0.90.70.50.60.80.90.90.6-0.90.1
Social time0.10.10.40.60.4-0.4-0.3-0.4-0.4-0.5-0.4-0.4-0.3-0.00.20.3-0.4-0.3-0.3
Soleus weight1.03.04.72.22.11.51.61.61.6-2.01.61.61.61.81.81.91.4-1.90.9
Bone: stiffness1.83.04.11.31.51.81.91.92.0-1.51.92.01.91.61.61.51.7-1.51.9
Tibialis anterior weight0.82.85.10.0-0.3-2.1-2.1-2.0-2.10.1-2.0-2.2-2.1-1.3-1.1-0.8-2.00.9-2.3
Time to tail flick, vehicle, before self-admin0.80.81.10.80.81.01.01.11.1-0.81.11.01.00.90.90.80.9-0.90.7
Time to tail flick, vehicle, after self-admin2.12.83.91.51.71.72.01.71.9-1.61.71.91.81.71.61.51.7-1.51.4
Time to tail flick, test, before self-admin1.01.01.7-0.6-0.6-1.0-1.0-1.1-1.01.0-1.1-1.1-1.1-1.0-0.9-0.9-1.21.0-1.3
Time to tail flick, test, after self-admin0.10.10.20.50.3-0.2-0.4-0.2-0.30.1-0.2-0.4-0.30.10.20.3-0.1-0.4-0.3
Delta time to tail flick, vehicle, before/after SA1.31.21.60.91.01.11.21.21.2-1.01.21.21.21.11.01.01.2-1.00.9
Delta time to tail flick, test, before/after SA0.50.50.80.50.50.60.50.80.7-0.30.80.70.70.70.70.80.9-0.90.9
Tibia length0.71.93.71.91.91.21.31.11.1-1.81.01.21.01.61.51.51.2-1.50.8
Ambulatory time before self-admin0.30.40.60.70.80.80.80.60.5-0.20.60.50.50.70.70.60.6-0.60.5
Ambulatory time after self-admin0.50.50.9-0.8-0.8-0.7-0.7-0.8-0.90.9-0.8-0.9-0.8-0.6-0.7-0.6-0.50.6-0.4
Bone: tissue strength0.50.50.6-0.7-0.8-0.7-0.8-0.7-0.70.8-0.7-0.8-0.7-0.7-0.7-0.7-0.70.7-0.2
Total heroin consumption0.20.20.90.70.5-0.3-0.3-0.3-0.3-1.0-0.3-0.4-0.30.10.30.3-0.1-0.3-0.7
Bone: trabecular number1.21.93.1-0.5-0.7-1.7-1.6-1.7-1.70.6-1.7-1.8-1.7-1.3-1.1-1.0-1.71.1-1.4
Bone: trabecular spacing0.71.03.2-1.8-1.6-0.5-0.4-0.5-0.61.7-0.5-0.4-0.5-1.0-1.1-1.3-0.41.3-0.2
Bone: trabecular thickness0.10.10.40.50.3-0.3-0.4-0.2-0.3-0.6-0.2-0.4-0.20.10.20.3-0.1-0.3-0.1
Bone: trabecular tissue density1.52.13.80.70.81.61.61.71.9-0.71.71.91.71.31.21.11.6-1.11.9
Water consumed over 24 hours0.81.02.0-0.6-0.7-1.2-1.0-1.2-0.90.7-1.2-0.9-1.1-1.0-1.0-0.9-1.20.9-1.4
Number of responses in last shaping day0.40.41.0-0.2-0.3-0.8-0.6-0.8-0.70.1-0.7-0.4-0.6-0.7-0.6-0.6-1.00.7-1.0