Hub : Genes

LOC120103631

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr6_131314090_131321875 0.02 0.02 4.5e-03 0.01 0.01 0.02 0.01 1.1e-02 9.7e-03 4.2e-03 7.9e-03
2 Liver gene expression LOC120103631 0.12 0.08 2.2e-16 0.1 0.12 0.1 0.12 1.0e-11 9.7e-14 9.8e-12 1.3e-13
3 Liver intron excision ratio chr6_131316407_131321875 0.03 0.03 7.7e-04 0.01 0.02 0.01 0.01 7.7e-03 3.9e-03 1.7e-02 8.5e-03
4 Adipose gene expression LOC120103631 0.04 0.03 9.7e-05 0.01 0.02 0.01 0.01 1.4e-02 2.8e-03 8.1e-03 9.6e-03
5 Liver mRNA stability LOC120103631 0.03 0.02 2.7e-03 0.02 0.02 0.01 0.01 4.2e-03 4.4e-03 9.0e-03 7.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5
Bone: apparent density0.00.00.00.0-0.10.1-0.10.2
Area under the delay curve0.10.10.20.5-0.30.2-0.20.3
BMI with tail2.47.88.22.7-2.92.8-2.82.8
BMI without tail0.61.31.71.3-1.11.1-1.11.1
Body weight0.62.43.6-1.91.4-1.51.4-1.5
Weight adjusted by age0.30.30.5-0.30.5-0.60.6-0.7
Bone surface0.10.10.50.7-0.30.2-0.20.2
Bone volume0.10.10.40.6-0.20.1-0.10.1
Breakpoint value in progressive ratio session0.20.30.4-0.0-0.50.6-0.60.6
Number of licking bursts0.10.10.40.7-0.20.2-0.10.2
Context. condit. distance diff. score3.54.25.0-1.92.0-2.12.1-2.2
Locomotion velocity, session 10.20.20.3-0.50.4-0.40.4-0.5
Locomotion distance, session 10.50.70.90.5-0.90.9-0.90.9
Locomotion velocity, session 20.00.00.00.2-0.0-0.00.00.0
Locomotion distance, session 20.40.51.01.0-0.70.6-0.60.6
Locomotion velocity, session 30.10.10.10.2-0.30.3-0.40.4
Locomotion distance, session 30.00.00.00.00.1-0.10.1-0.1
Stereotopy head waving bouts, day 30.00.00.1-0.30.3-0.20.2-0.1
Stereotopy head waving duration, day 30.10.10.2-0.30.4-0.40.4-0.3
Locomotion velocity, session 70.20.20.30.0-0.40.5-0.50.5
Locomotion distance, session 70.70.91.01.0-1.00.9-0.90.9
Stereotopy head waving bouts, day 71.61.82.8-1.71.4-1.31.2-1.2
Stereotopy head waving duration, day 70.60.81.6-1.30.8-0.80.7-0.7
Locomotion velocity, session 80.91.11.3-1.11.0-1.01.0-1.1
Locomotion distance, session 80.20.30.5-0.30.4-0.60.5-0.7
Degree of sensitization distance0.20.20.20.5-0.50.5-0.50.5
Degree of sensitization stereotypy0.40.40.9-1.00.6-0.60.5-0.5
Conditioned locomotion1.41.72.0-1.41.3-1.31.3-1.2
Cocaine response after cond. corrected0.91.01.50.5-0.91.1-1.11.2
Cocaine response after cond. not corrected2.22.43.11.0-1.51.7-1.71.8
Cocaine response before conditioning1.62.02.51.3-1.61.4-1.41.3
Saline control response0.10.10.3-0.5-0.10.1-0.1-0.0
Bone: connectivity density0.20.40.5-0.50.6-0.60.6-0.7
Bone: cortical apparent density7.29.410.2-3.13.2-3.03.1-2.9
Bone: cortical area0.30.40.6-0.70.8-0.60.6-0.4
Bone: cortical porosity0.30.30.5-0.20.5-0.60.6-0.7
Bone: cortical porosity0.00.00.00.1-0.0-0.10.1-0.2
Bone: cortical thickness0.30.51.4-1.20.8-0.50.5-0.3
Bone: cortical thickness0.80.91.0-1.01.0-1.01.0-0.8
Bone: cortical tissue density7.39.610.4-3.13.2-3.13.1-3.0
Condit. Reinf. active minus inactive responses0.60.70.90.5-0.80.9-0.91.0
Condit. Reinf. active-inactive response ratio2.72.93.11.5-1.81.8-1.81.8
Condit. Reinf. active responses0.20.20.4-0.1-0.30.5-0.50.6
Condit. Reinf. inactive responses1.72.03.2-1.81.5-1.31.3-1.1
Incentive salience index mean0.50.61.00.2-0.80.9-0.91.0
Condit. Reinf. lever presses0.10.20.3-0.2-0.30.5-0.50.6
Condit. Reinf. active minus inactive responses0.81.01.5-0.41.0-1.11.1-1.2
Condit. Reinf. active-inactive response ratio0.70.81.10.30.8-1.01.0-1.1
Condit. Reinf. active responses0.10.10.2-0.00.3-0.40.3-0.4
Condit. Reinf. inactive responses0.30.40.6-0.1-0.70.7-0.70.8
Condit. Reinf. lever presses0.81.11.81.3-1.20.9-1.00.8
Condit. Reinf. lever reinforcers received0.10.20.3-0.10.3-0.50.5-0.6
Conditioned reinforcement - actives2.02.02.1-1.41.5-1.41.4-1.4
Conditioned reinforcement - inactives0.50.60.9-1.00.8-0.70.7-0.6
Conditioned locomotion0.30.30.40.3-0.60.6-0.60.6
Patch foraging indifference point 0 sec4.36.98.9-3.02.7-2.52.5-2.3
Patch foraging indifference point AUC2.62.96.3-2.51.7-1.41.4-1.3
Delay disc. indifference point, 0s delay0.30.30.5-0.70.5-0.50.5-0.5
Delay disc. indifference point, 16s delay0.10.10.40.6-0.40.3-0.30.2
Delay disc. indifference point, 2s delay0.60.61.21.1-0.70.7-0.60.7
Delay disc. indifference point, 24s delay0.30.30.30.6-0.50.5-0.50.5
Delay disc. indifference point, 4s delay0.20.20.3-0.10.4-0.50.5-0.5
Delay disc. indifference point, 8s delay0.00.00.10.3-0.30.2-0.20.2
Indifference point function ln k1.11.62.0-0.71.2-1.41.4-1.4
Indifference point function log k1.11.62.0-0.71.2-1.41.4-1.4
Patch foraging total patch changes 0 sec5.08.110.6-3.32.9-2.72.7-2.5
Patch foraging total patch changes 12 sec3.85.06.0-2.52.3-2.12.2-2.0
Patch foraging total patch changes 18 sec1.51.93.5-1.91.5-1.21.2-1.0
Patch foraging total patch changes 24 sec0.40.51.1-1.00.7-0.50.5-0.4
Patch foraging total patch changes 6 sec2.43.67.5-2.71.9-1.61.6-1.4
Patch foraging time to switch 0 sec10.916.820.64.5-4.23.9-4.03.8
Patch foraging water rate 0 sec18.229.232.7-5.75.6-5.35.3-5.1
Patch foraging water rate 12 sec10.315.817.0-3.74.0-4.14.1-3.9
Patch foraging water rate 18 sec5.16.97.5-2.42.7-2.72.7-2.5
Patch foraging water rate 24 sec4.25.86.4-2.12.5-2.52.5-2.4
Patch foraging water rate 6 sec4.97.27.6-2.72.8-2.72.7-2.5
Seeking ratio, delayed vs. immediate footshock0.30.40.4-0.60.6-0.60.6-0.6
Distance traveled before self-admin0.40.40.60.6-0.60.7-0.60.8
Distance traveled after self-admin0.50.50.7-0.50.8-0.80.8-0.7
Extensor digitorum longus weight7.830.836.7-6.15.5-5.45.3-5.4
Bone: elastic displacement0.40.50.6-0.40.7-0.80.8-0.7
Bone: elastic work0.10.10.20.50.1-0.20.3-0.2
Bone: endosteal estimation0.30.62.41.5-0.50.2-0.20.1
Bone: endosteal perimeter0.10.10.40.7-0.20.2-0.20.1
Epididymis fat weight3.88.89.32.8-3.13.0-3.03.0
Delta time in closed arm before/after self-admin0.00.00.10.30.0-0.10.1-0.1
Delta time in open arm before/after self-admin0.80.82.9-1.70.6-0.50.5-0.4
Diff in mean of infusions in LGA sessions0.10.10.1-0.4-0.10.3-0.30.4
Delay discount exponential model param0.00.10.2-0.40.2-0.10.1-0.2
Extinction: sum of active levers before priming0.10.10.1-0.1-0.30.4-0.40.3
Active lever presses in extinction session 61.81.72.0-1.41.2-1.31.3-1.4
Bone: final force0.20.30.40.20.5-0.60.6-0.6
Bone: final moment0.20.40.50.00.6-0.70.7-0.7
Food consumed during 24 hour testing period0.60.71.5-1.20.7-0.70.7-0.7
Glucose0.30.50.7-0.70.9-0.70.8-0.4
Heart weight0.00.00.10.3-0.0-0.10.1-0.2
Delay discount hyperbolic model param0.10.10.2-0.50.3-0.20.2-0.3
Intermittent access intake day 1-15 change1.61.61.91.0-1.31.3-1.31.4
Intermittent access intake escalation1.71.71.81.1-1.31.3-1.31.3
Intermittent access intake escalation 20.30.30.40.2-0.60.7-0.60.7
Intermitt. access day 1 inactive lever presses3.43.63.8-2.01.9-1.91.9-1.9
Intermitt. access day 15 inactive lever presses1.11.21.3-1.01.1-1.11.1-1.1
Intermitt. access escalation Index0.20.20.3-0.00.5-0.50.5-0.5
Intermittent access day 1 total infusions0.10.20.20.2-0.40.4-0.40.5
Intermittent access day 15 total infusions1.61.82.11.2-1.41.4-1.41.5
Intermittent access terminal intake (last 3 days)2.02.12.90.9-1.51.5-1.51.7
Intermittent access total infusions0.50.50.80.5-0.70.7-0.80.9
Intermittent access day 1 locomotion0.40.40.50.3-0.70.7-0.70.7
Intermittent access day 15 total locomotion0.10.10.10.3-0.40.3-0.30.3
Intermittent access total locomotion0.20.20.40.1-0.50.5-0.50.6
Intermittent access standard deviation3.23.44.31.1-1.92.0-2.02.1
Left kidney weight1.74.95.4-2.02.2-2.32.2-2.3
Right kidney weight1.13.13.8-1.41.7-1.91.8-2.0
Cocaine induced anxiety1.82.02.3-1.21.5-1.41.5-1.5
Post-drug Anxiety1.21.31.5-1.11.2-1.11.2-1.2
Baseline Anxiety1.61.72.01.1-1.31.3-1.31.4
Tail length4.513.716.0-4.03.7-3.73.6-3.6
Length with tail6.824.931.0-5.64.9-4.94.8-4.8
Length without tail3.47.510.1-3.22.7-2.62.6-2.6
Times rat made contact with spout0.20.20.7-0.80.4-0.20.3-0.2
Lifetime Intake0.20.20.30.3-0.40.4-0.40.6
Liver weight, left2.33.74.7-2.22.0-1.81.9-1.7
Liver weight, right0.10.10.6-0.80.2-0.10.0-0.0
Locomotor activity0.20.30.4-0.50.5-0.60.6-0.6
Locomotor testing distance0.40.60.7-0.70.8-0.80.8-0.8
Locomotor testing rearing1.62.42.71.5-1.61.6-1.61.5
Locomotion in novel chamber6.37.78.3-2.52.8-2.92.9-2.8
Locomotion in novel chamber post-restriction0.10.10.30.5-0.2-0.0-0.0-0.1
Fecal boli incidents, locomotor time 12.32.53.01.1-1.61.7-1.71.7
Change in fecal boli incidents, locomotor task2.22.12.9-0.91.4-1.61.5-1.7
Time >=10cm from walls, locomotor time 10.10.10.2-0.4-0.30.4-0.40.4
Bouts of movement, locomotor time 11.82.02.61.1-1.41.5-1.51.6
Total resting periods, locomotor time 11.71.92.31.1-1.41.4-1.41.5
Rest time, locomotor task time 10.00.00.1-0.00.00.1-0.00.3
Distance moved, locomotor task time 10.30.30.91.0-0.50.4-0.30.1
Vertical activity count, locomotor time 10.30.30.4-0.10.5-0.50.6-0.6
Time >=10cm from walls, locomotor time 20.70.71.9-1.40.8-0.60.6-0.6
Bouts of movement, locomotor time 21.61.72.1-1.01.3-1.41.4-1.4
Total resting periods, locomotor time 21.21.31.6-0.81.1-1.21.3-1.2
Rest time, locomotor task time 20.10.10.2-0.30.4-0.40.4-0.2
Distance moved, locomotor task time 20.30.30.50.7-0.60.6-0.50.4
Vertical activity count, locomotor time 20.10.10.2-0.40.4-0.30.4-0.3
Light reinforcement 10.00.00.00.10.1-0.10.10.0
Light reinforcement 22.12.93.01.6-1.71.7-1.71.7
Bone: marrow area0.20.52.31.5-0.50.2-0.20.1
Bone: maximum diameter0.10.20.40.3-0.30.5-0.40.7
Bone: maximum force0.10.20.3-0.00.5-0.60.6-0.5
Bone: maximum moment0.10.20.3-0.10.5-0.60.6-0.6
Mean time between licks in bursts0.50.60.80.9-0.90.8-0.80.6
Mean num. licks in bursts0.20.31.1-1.00.4-0.30.3-0.2
Cd content in liver2.02.23.2-1.21.3-1.61.5-1.8
Co content in liver1.41.61.9-1.21.2-1.31.3-1.4
Cu content in liver1.92.32.51.4-1.61.6-1.51.6
Fe content in liver0.50.60.91.0-0.70.7-0.70.7
K content in liver0.20.20.6-0.80.4-0.30.3-0.2
Mg content in liver0.10.10.1-0.30.4-0.40.4-0.4
Mn content in liver0.40.50.70.20.6-0.80.7-0.9
Na content in liver0.40.40.70.3-0.50.7-0.70.8
Rb content in liver1.01.21.6-0.51.1-1.21.2-1.3
Se content in liver0.00.00.1-0.2-0.30.2-0.20.1
Sr content in liver0.40.40.5-0.50.6-0.70.7-0.7
Zn content in liver0.10.10.3-0.50.4-0.40.4-0.3
Bone: minimum diameter0.81.51.7-0.81.2-1.31.3-1.3
Time in familiar zone, hab. session 10.00.00.10.2-0.30.2-0.20.0
Time in novel zone, hab. session 10.40.40.70.8-0.50.5-0.50.6
Total zone transitions, hab. session 10.30.41.31.1-0.60.3-0.40.2
Total locomotion distance, hab. session 10.40.61.00.10.6-0.90.9-1.0
Locomotion velocity, hab. session 10.91.31.6-0.71.1-1.21.2-1.3
Time in familiar zone, hab. session 20.10.10.2-0.1-0.40.4-0.40.2
Time in novel zone, hab. session 20.20.20.50.7-0.40.3-0.30.4
Total zone transitions, hab. session 20.60.81.00.7-0.90.9-1.01.0
Total locomotion distance, hab. session 20.30.40.5-0.60.7-0.70.7-0.5
Locomotion velocity, hab. session 20.50.60.7-0.80.9-0.80.8-0.6
Novel to familiar place preference ratio0.60.60.70.7-0.80.8-0.80.9
Novelty place preference0.40.40.50.7-0.60.6-0.60.7
Time in novel zone, NPP test0.20.20.20.4-0.50.5-0.50.5
Total zone transitions, NPP test0.10.10.1-0.30.2-0.30.2-0.3
Total locomotion distance, NPP test0.20.30.4-0.50.5-0.60.6-0.6
Locomotion velocity, NPP test0.20.30.4-0.40.5-0.60.6-0.6
Intraocular pressure0.00.00.00.2-0.20.1-0.10.1
Delta distance traveled before/after self-admin0.40.50.5-0.70.6-0.70.7-0.7
Delta ambulatory time before/after self-admin1.61.82.0-1.31.2-1.41.4-1.4
Parametrial fat weight0.00.10.10.2-0.20.2-0.20.3
Pavlov. Cond. lever latency0.70.91.3-0.50.9-1.01.0-1.1
Pavlov. Cond. magazine entry latency0.40.50.60.4-0.80.8-0.80.8
Pavlov. Cond. change in total contacts0.20.20.40.1-0.50.5-0.60.6
Pavlov. Cond. index score0.91.11.40.6-1.11.2-1.21.2
Pavlov. Cond. latency score0.70.81.10.4-0.91.0-1.01.1
Pavlov. Cond. lever contacts1.21.42.00.8-1.21.3-1.31.4
Pavlov. Cond. magazine entry number0.70.81.1-0.61.0-1.01.0-1.0
Pavlov. Cond. intertrial magazine entries6.88.211.2-3.32.9-2.72.7-2.7
Pavlov. Cond. lever-magazine prob. diff.0.70.91.20.5-1.01.0-1.11.1
Pavlov. Cond. response bias0.91.11.40.5-1.11.1-1.21.2
Pavlov. Cond. lever latency1.62.13.4-1.81.5-1.31.3-1.2
Pavlov. Cond. magazine entry latency3.74.34.92.0-2.22.0-2.12.0
Pavlov. Cond. change in total contacts4.05.57.02.6-2.42.3-2.32.1
Pavlov. Cond. index score3.64.65.92.4-2.32.0-2.11.9
Pavlov. Cond. latency score3.74.75.52.3-2.32.1-2.11.9
Pavlov. Cond. lever contacts2.23.03.71.9-1.91.6-1.71.5
Pavlov. Cond. magazine entry number2.93.54.1-2.02.0-1.81.8-1.8
Pavlov. Cond. intertrial magazine entries5.57.28.0-2.82.8-2.62.7-2.5
Pavlov. Cond. lever-magazine prob. diff.4.25.46.72.6-2.52.2-2.22.1
Pavlov. Cond. response bias2.53.54.22.1-2.01.7-1.81.6
Time in closed arm before self-admin4.14.75.32.3-2.22.1-2.12.0
Time in closed arm after self-admin1.71.83.81.9-1.31.1-1.11.0
Time in open arm before self-admin5.96.47.1-2.02.7-2.62.6-2.6
Time in open arm after self-admin4.85.38.8-3.02.2-2.12.0-2.0
Bone: periosteal estimation0.00.10.20.50.2-0.30.3-0.2
Bone: periosteal perimeter0.00.00.00.1-0.00.1-0.10.1
Bone: post-yield work2.02.73.2-1.51.6-1.71.7-1.8
Progressive ratio test 1 active lever presses0.00.00.0-0.1-0.00.0-0.00.2
Progressive ratio test 1 breakpoint0.10.10.2-0.0-0.20.2-0.20.5
Progressive ratio test 1 inactive lever presses3.13.43.6-1.81.9-1.91.9-1.7
Progressive ratio test 2 active lever presses0.00.00.10.4-0.00.0-0.00.1
Progressive ratio test 2 breakpoint0.00.00.10.20.1-0.10.1-0.0
Progressive ratio test 2 inactive lever presses0.70.81.0-0.50.9-1.01.0-0.9
Incentive Sensitization - Responses0.10.10.40.6-0.0-0.00.00.0
Incentive Sensitization - Breakpoint0.10.10.30.60.1-0.20.2-0.1
Sum of active levers in priming session hrs 5-60.70.70.90.6-0.80.9-0.91.0
Progressive ratio0.20.20.30.40.4-0.50.6-0.4
Food seeking constrained by brief footshock0.70.81.2-1.11.0-0.90.9-0.6
Seeking ratio, punishment vs. effort0.20.20.9-1.00.3-0.20.2-0.1
Retroperitoneal fat weight0.20.71.00.4-0.80.9-0.91.0
Reaction time number correct3.65.26.7-2.62.3-2.22.2-2.1
Reaction time mean minus median0.10.10.10.1-0.30.3-0.30.3
Reaction time mean minus median AUC0.00.00.00.1-0.20.1-0.10.1
Reaction time num false alarms1.21.62.8-1.71.3-1.21.2-1.0
Reaction time num false alarms AUC1.62.23.2-1.81.5-1.41.4-1.2
Reaction time trials correct on left3.65.26.7-2.62.3-2.22.2-2.1
Reaction time trials on left3.75.36.7-2.62.4-2.22.2-2.1
Reaction time mean0.81.11.91.4-1.10.9-0.90.9
Reaction time mean AUC0.40.61.11.0-0.80.6-0.60.6
Median of all reaction times0.50.61.51.2-0.80.6-0.60.6
Reaction time omissions1.41.92.1-1.41.4-1.51.4-1.3
Reaction time false alarm rate0.10.10.3-0.50.4-0.30.3-0.2
Reaction time premature initiation rate0.60.80.9-0.60.9-0.90.9-1.0
Reaction time premature initiations2.43.43.7-1.81.9-1.81.9-1.8
Std. dev. reaction times0.40.50.80.9-0.80.6-0.60.6
Reaction time trials completed3.75.36.7-2.62.4-2.22.2-2.1
Reaction time trials AUC3.95.56.9-2.62.4-2.32.3-2.1
Run reversals in cocaine runway, females1.61.51.91.4-1.21.2-1.21.2
Run reversals in cocaine runway, males0.20.20.3-0.30.5-0.40.5-0.4
Latency to leave start box in cocaine runway0.30.30.40.5-0.50.6-0.50.6
Latency to leave start box in cocaine runway, F0.40.40.60.4-0.60.8-0.70.8
Latency to leave start box in cocaine runway, M0.30.30.50.4-0.50.5-0.50.7
Std. dev. time between licks in bursts0.00.00.10.2-0.20.0-0.1-0.1
Total sessions with >9 infusions0.00.00.0-0.1-0.10.1-0.10.2
Short access day 1 total inactive lever presses0.00.10.10.20.1-0.20.2-0.4
Short access day 10 total inactive lever presses0.70.81.0-0.40.9-1.01.0-1.0
Short access day 1 total infusions0.30.30.4-0.60.5-0.60.6-0.6
Short access day 10 total infusions0.30.30.40.5-0.50.5-0.50.6
Short access total infusions0.10.10.20.4-0.40.3-0.30.4
Short access day 1 locomotion0.20.30.40.2-0.60.5-0.60.5
Short access day 10 total locomotion0.40.50.80.1-0.70.7-0.70.9
Short access total locomotion0.00.00.1-0.2-0.10.1-0.10.3
One hour access (0.3 mA shock)0.20.20.5-0.70.4-0.30.3-0.2
Compulsive drug intake0.00.00.1-0.30.0-0.00.0-0.2
One hour access (shock baseline)0.00.00.1-0.1-0.10.2-0.20.3
Social response proportion0.30.30.40.30.5-0.60.6-0.7
Social responses0.10.10.30.6-0.20.1-0.10.1
Social time1.62.13.2-0.61.3-1.61.6-1.8
Soleus weight0.20.72.5-1.60.6-0.50.4-0.6
Bone: stiffness1.32.12.2-1.31.5-1.51.5-1.5
Tibialis anterior weight0.51.63.2-1.81.2-1.11.1-1.1
Time to tail flick, vehicle, before self-admin0.50.60.8-0.60.9-0.80.7-0.7
Time to tail flick, vehicle, after self-admin0.10.10.4-0.60.1-0.10.0-0.1
Time to tail flick, test, before self-admin0.00.00.00.10.2-0.20.2-0.0
Time to tail flick, test, after self-admin2.02.12.5-1.61.5-1.41.4-1.3
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.70.0-0.0-0.0-0.0
Delta time to tail flick, test, before/after SA2.01.83.1-1.81.3-1.21.2-1.2
Tibia length0.10.30.4-0.60.6-0.50.5-0.3
Ambulatory time before self-admin0.80.81.10.7-0.81.0-0.91.0
Ambulatory time after self-admin0.00.00.10.2-0.10.1-0.10.1
Bone: tissue strength0.00.00.10.4-0.10.1-0.10.2
Total heroin consumption0.50.61.5-1.20.8-0.60.6-0.4
Bone: trabecular number0.20.30.3-0.50.5-0.60.5-0.6
Bone: trabecular spacing0.10.10.10.2-0.30.3-0.30.4
Bone: trabecular thickness0.00.10.1-0.30.3-0.20.2-0.2
Bone: trabecular tissue density0.00.00.2-0.40.20.00.00.1
Water consumed over 24 hours2.63.13.6-1.51.9-1.81.9-1.7
Number of responses in last shaping day0.50.50.60.8-0.70.7-0.70.8