Hub : Genes

LOC120103571

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr6_106635746_106660864 0.16 0.08 1.4e-05 0.07 0.1 0.1 0.09 1.1e-04 8.6e-06 3.6e-06 2.6e-05
2 BLA gene expression LOC120103571 0.07 0.04 2.7e-03 0.03 0.04 0.04 0.03 1.5e-02 2.3e-03 2.8e-03 1.1e-02
3 NAcc gene expression LOC120103571 0.05 0.03 4.8e-08 0.03 0.05 0.04 0.04 2.8e-05 6.2e-08 4.5e-07 9.1e-07
4 PL intron excision ratio chr6_106635746_106660864 0.07 0.04 1.1e-04 0.01 0.03 0.03 0.03 2.9e-02 4.3e-04 2.2e-04 2.7e-04
5 IC intron excision ratio chr6_106635746_106653735 0.11 0.06 1.6e-03 0.1 0.1 0.1 0.12 4.9e-05 7.8e-05 5.0e-05 1.6e-05
6 Brain gene expression LOC120103571 0.06 0.03 2.7e-05 0.07 0.05 0.06 0.06 4.4e-07 2.8e-05 2.1e-06 2.4e-06
7 Brain isoform ratio XR_005506091.2 0.03 0.02 4.2e-03 0.01 0.02 0.01 0.01 8.1e-02 3.0e-03 1.7e-02 2.2e-02
8 PL gene expression LOC120103571 0.17 0.06 1.9e-11 0.11 0.1 0.09 0.1 5.0e-12 8.9e-11 1.5e-09 4.9e-11
9 Brain alternative TSS XR_010052271.1 0.03 0.02 5.3e-03 0.01 0.02 0.01 0.01 7.2e-02 8.9e-03 1.5e-02 3.2e-02
10 Brain alternative TSS XR_005506091.2 0.03 0.02 5.8e-03 0 0.02 0.01 0.01 1.1e-01 9.2e-03 1.5e-02 3.6e-02
11 PL alternative TSS XR_005506091.2 0.05 0.02 5.9e-04 0.03 0.02 0.02 0.03 2.3e-04 2.5e-03 2.0e-03 9.3e-04
12 PL alternative TSS XR_010052271.1 0.05 0.03 4.9e-04 0.03 0.02 0.02 0.03 1.8e-04 2.1e-03 1.2e-03 5.1e-04
13 NAcc alternative TSS XR_010052271.1 0.02 0.01 7.1e-03 0.01 0.01 0.01 0 2.1e-02 3.1e-02 1.3e-02 8.8e-02
14 NAcc alternative TSS XR_005506091.2 0.02 0.01 7.4e-03 0.01 0.01 0.01 0 1.9e-02 3.6e-02 1.6e-02 7.7e-02
15 NAcc intron excision ratio chr6_106635746_106660864 0.08 0.04 6.9e-09 0.06 0.06 0.05 0.06 2.8e-09 5.4e-09 1.8e-08 4.9e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.30.51.70.50.71.01.3-0.40.31.00.2-0.90.90.7-0.70.0-0.10.5
Area under the delay curve0.30.30.80.60.80.90.8-0.10.40.70.7-0.60.60.3-0.3-0.20.20.4
BMI with tail1.65.614.43.80.21.13.6-2.01.82.7-0.2-2.42.42.7-2.72.3-2.32.0
BMI without tail1.13.38.70.52.62.92.5-0.92.32.51.4-2.22.21.2-1.2-0.0-0.21.3
Body weight0.83.412.7-1.23.53.60.80.42.21.82.6-1.61.60.5-0.5-1.31.10.4
Weight adjusted by age1.62.55.90.02.22.42.31.80.40.32.10.2-0.2-1.71.70.9-1.12.3
Bone surface0.50.93.21.00.71.11.80.9-0.50.10.60.2-0.2-0.60.61.1-1.21.7
Bone volume0.10.31.10.00.70.91.00.6-0.40.10.30.00.0-0.10.10.2-0.30.8
Breakpoint value in progressive ratio session1.21.55.51.10.50.71.31.2-1.0-0.40.30.7-0.7-1.51.51.5-1.62.3
Number of licking bursts0.50.82.91.7-0.8-0.51.1-0.90.50.7-0.3-0.60.60.9-0.91.0-1.00.9
Context. condit. distance diff. score0.50.62.0-0.90.90.7-1.2-0.00.70.20.7-0.30.3-0.10.1-1.41.4-0.9
Locomotion velocity, session 10.70.71.30.2-0.9-0.9-0.60.7-0.9-1.1-0.31.1-1.1-1.11.10.7-0.70.7
Locomotion distance, session 10.91.12.81.5-0.8-0.51.2-1.70.61.1-1.0-1.11.11.3-1.30.7-0.70.6
Locomotion velocity, session 20.80.92.3-0.5-1.0-1.0-0.6-1.50.40.5-0.9-0.70.71.4-1.4-1.01.1-1.1
Locomotion distance, session 21.11.54.21.2-1.6-1.30.8-2.00.30.9-1.7-1.01.01.6-1.60.7-0.60.2
Locomotion velocity, session 32.02.37.7-2.8-0.6-1.2-2.5-0.0-0.6-0.9-0.70.6-0.5-0.10.1-2.52.5-2.1
Locomotion distance, session 30.10.10.3-0.5-0.2-0.2-0.30.4-0.5-0.5-0.10.5-0.5-0.40.4-0.30.30.2
Stereotopy head waving bouts, day 30.20.30.8-0.80.90.80.00.70.2-0.00.50.1-0.1-0.00.0-0.70.6-0.5
Stereotopy head waving duration, day 30.50.62.5-1.50.0-0.2-0.80.4-0.3-0.5-0.40.3-0.30.1-0.1-1.11.1-1.6
Locomotion velocity, session 71.11.22.9-0.8-1.4-1.7-1.30.6-1.2-1.5-1.21.3-1.3-0.60.6-0.50.6-0.6
Locomotion distance, session 70.70.82.60.4-0.4-0.50.2-1.60.91.0-0.9-1.11.11.4-1.4-0.40.4-0.3
Stereotopy head waving bouts, day 70.80.93.8-2.01.51.1-0.71.00.0-0.10.70.1-0.1-0.30.3-1.51.4-0.8
Stereotopy head waving duration, day 71.21.56.4-2.51.61.2-0.90.60.30.20.6-0.20.2-0.00.0-2.11.9-1.4
Locomotion velocity, session 80.20.20.6-0.1-0.7-0.8-0.7-0.70.1-0.0-0.7-0.20.20.2-0.2-0.30.4-0.4
Locomotion distance, session 80.60.92.90.3-0.1-0.1-0.0-1.71.11.2-0.6-1.31.31.3-1.3-0.70.7-0.4
Degree of sensitization distance0.50.51.30.10.20.0-0.2-1.11.10.9-0.1-1.01.00.9-0.9-0.50.5-0.7
Degree of sensitization stereotypy1.01.03.7-1.91.41.1-1.00.90.0-0.10.90.1-0.1-0.60.6-1.61.4-0.8
Conditioned locomotion1.31.53.4-0.3-1.6-1.9-1.70.5-1.7-1.7-1.21.4-1.4-0.50.5-0.20.3-1.0
Cocaine response after cond. corrected1.21.43.51.0-1.8-1.9-0.50.5-1.8-1.5-1.21.4-1.4-0.60.60.9-0.80.1
Cocaine response after cond. not corrected1.21.44.21.0-2.0-2.1-0.30.1-1.6-1.2-1.71.1-1.1-0.30.30.9-0.80.1
Cocaine response before conditioning0.20.20.70.00.00.10.8-0.50.50.6-0.7-0.50.50.4-0.40.3-0.30.2
Saline control response0.60.82.20.4-0.6-0.40.4-1.50.40.9-1.1-1.01.01.3-1.3-0.40.5-0.4
Bone: connectivity density0.71.13.71.00.91.31.9-0.60.81.40.7-1.21.20.9-0.90.5-0.60.9
Bone: cortical apparent density0.60.82.2-0.0-0.1-0.0-0.3-1.20.60.8-0.1-1.01.01.2-1.2-1.11.2-1.5
Bone: cortical area0.60.92.2-1.30.60.3-1.01.5-0.7-1.00.61.0-1.0-1.11.1-0.70.7-0.6
Bone: cortical porosity0.70.83.0-1.31.71.4-0.10.81.00.41.2-0.20.2-0.50.5-0.60.50.4
Bone: cortical porosity0.80.93.2-1.11.81.6-0.11.10.80.11.50.1-0.0-0.90.9-0.50.30.4
Bone: cortical thickness0.40.72.1-1.10.30.1-0.7-0.60.70.6-0.1-0.70.70.7-0.7-1.41.4-1.3
Bone: cortical thickness0.60.72.4-0.1-1.2-1.5-0.8-0.8-0.6-0.1-1.5-0.10.10.7-0.7-0.30.4-1.3
Bone: cortical tissue density0.50.61.90.1-0.1-0.1-0.3-1.10.50.7-0.1-0.90.91.0-1.0-0.91.0-1.4
Condit. Reinf. active minus inactive responses1.01.23.4-1.51.81.6-0.80.40.90.51.6-0.40.5-0.50.5-1.31.2-1.0
Condit. Reinf. active-inactive response ratio1.01.13.0-1.51.71.4-0.90.60.80.21.6-0.20.2-0.60.6-1.31.2-1.1
Condit. Reinf. active responses1.01.23.7-1.21.91.6-1.00.51.10.61.8-0.60.6-0.50.5-1.11.1-1.0
Condit. Reinf. inactive responses0.40.51.20.80.70.70.5-0.51.01.10.6-1.01.00.4-0.40.4-0.40.4
Incentive salience index mean0.70.82.2-1.21.51.2-1.00.80.40.01.50.0-0.0-0.90.9-0.80.8-0.6
Condit. Reinf. lever presses0.30.41.4-0.20.40.3-0.51.0-0.2-0.50.50.6-0.6-1.21.20.4-0.40.3
Condit. Reinf. active minus inactive responses1.31.74.00.81.01.11.2-1.71.82.00.7-1.91.91.2-1.2-0.10.10.4
Condit. Reinf. active-inactive response ratio1.31.53.40.41.21.41.0-1.41.91.80.9-1.71.71.1-1.1-0.60.50.1
Condit. Reinf. active responses0.30.41.0-0.00.70.80.5-0.70.81.00.4-1.01.00.3-0.3-0.40.30.6
Condit. Reinf. inactive responses0.60.71.3-0.7-0.7-0.9-1.00.9-1.1-1.1-0.61.1-1.1-1.01.0-0.10.20.5
Condit. Reinf. lever presses0.40.51.50.40.50.60.30.9-0.4-0.40.60.5-0.5-1.11.10.6-0.71.2
Condit. Reinf. lever reinforcers received0.40.51.30.20.70.80.5-0.80.81.10.5-1.01.00.3-0.3-0.20.20.7
Conditioned reinforcement - actives0.71.13.0-1.3-0.3-0.6-0.4-1.30.50.7-0.8-0.90.91.3-1.3-1.31.3-1.7
Conditioned reinforcement - inactives0.30.51.2-0.0-1.1-1.1-0.10.5-1.1-0.7-0.90.7-0.7-0.20.20.6-0.50.4
Conditioned locomotion1.11.43.7-0.4-1.2-1.4-0.3-1.60.20.6-1.9-0.90.91.7-1.7-0.80.9-1.5
Patch foraging indifference point 0 sec0.30.51.4-0.20.91.21.1-0.11.00.90.4-0.70.70.8-0.8-0.10.10.3
Patch foraging indifference point AUC0.30.41.5-0.4-0.1-0.3-1.20.4-0.4-0.4-0.20.3-0.20.3-0.3-1.11.1-0.9
Delay disc. indifference point, 0s delay1.41.63.21.20.91.11.7-1.41.61.80.5-1.71.71.2-1.20.3-0.40.7
Delay disc. indifference point, 16s delay0.91.02.8-1.20.40.3-0.81.7-1.0-1.10.71.2-1.2-1.41.4-0.70.60.3
Delay disc. indifference point, 2s delay1.51.73.50.51.61.61.0-1.01.61.91.1-1.81.81.4-1.4-0.50.4-0.2
Delay disc. indifference point, 24s delay0.20.31.0-0.20.70.90.40.80.2-0.01.00.2-0.2-0.40.40.1-0.10.6
Delay disc. indifference point, 4s delay0.50.62.61.60.60.80.90.30.50.41.2-0.10.2-0.20.20.6-0.71.1
Delay disc. indifference point, 8s delay1.11.32.90.81.11.31.4-1.10.81.70.4-1.61.61.3-1.3-0.60.50.0
Indifference point function ln k0.50.93.1-1.11.81.71.10.01.10.91.2-0.70.7-0.20.2-0.0-0.10.6
Indifference point function log k0.50.93.1-1.11.81.71.10.01.10.91.2-0.70.7-0.20.2-0.0-0.10.6
Patch foraging total patch changes 0 sec0.40.82.2-0.21.21.51.3-0.11.21.00.7-0.90.90.8-0.8-0.20.10.3
Patch foraging total patch changes 12 sec0.30.41.6-0.11.11.30.20.80.50.51.0-0.30.40.5-0.5-0.70.60.1
Patch foraging total patch changes 18 sec0.10.20.60.40.50.70.70.8-0.00.30.5-0.20.20.6-0.6-0.20.10.3
Patch foraging total patch changes 24 sec0.91.65.5-2.11.31.0-1.20.50.70.50.7-0.50.50.7-0.7-2.32.3-1.4
Patch foraging total patch changes 6 sec0.20.20.7-0.60.50.4-0.40.00.30.20.2-0.30.30.7-0.7-0.80.8-0.5
Patch foraging time to switch 0 sec0.51.12.50.1-1.6-1.5-0.90.5-1.3-1.5-0.91.4-1.4-0.80.80.5-0.4-0.2
Patch foraging water rate 0 sec1.02.17.4-1.12.72.60.70.11.71.71.9-1.51.50.4-0.4-1.10.90.1
Patch foraging water rate 12 sec0.40.91.8-1.31.10.8-0.4-0.41.20.90.6-1.01.00.7-0.7-1.11.1-1.0
Patch foraging water rate 18 sec3.35.18.9-1.82.52.20.4-2.02.92.90.8-3.03.02.2-2.2-2.32.2-1.2
Patch foraging water rate 24 sec2.53.56.7-1.22.22.11.0-1.72.32.60.7-2.62.61.8-1.8-1.51.5-1.2
Patch foraging water rate 6 sec1.11.65.7-1.42.42.20.20.21.51.31.5-1.11.10.2-0.2-1.11.0-0.1
Seeking ratio, delayed vs. immediate footshock0.40.51.5-1.10.0-0.4-1.20.3-0.2-0.70.40.6-0.6-0.80.8-1.01.0-0.6
Distance traveled before self-admin0.60.82.41.10.40.51.5-0.70.91.1-0.1-1.01.01.1-1.10.3-0.30.5
Distance traveled after self-admin1.11.33.10.21.21.51.8-0.61.51.60.3-1.41.41.2-1.2-0.30.30.3
Extensor digitorum longus weight0.10.52.4-0.11.11.1-0.40.60.6-0.11.50.2-0.2-0.80.8-0.40.30.1
Bone: elastic displacement0.50.61.3-0.5-0.9-1.1-0.8-0.80.10.0-1.1-0.20.20.8-0.8-0.70.8-1.1
Bone: elastic work1.92.45.1-1.30.2-0.0-0.7-1.81.51.4-0.5-1.61.62.0-2.0-2.02.0-2.3
Bone: endosteal estimation1.22.77.4-0.7-0.0-0.2-0.72.7-2.4-2.30.12.4-2.3-2.22.20.5-0.60.4
Bone: endosteal perimeter1.42.97.1-1.10.2-0.0-0.92.7-1.8-2.30.42.4-2.4-2.62.60.3-0.40.5
Epididymis fat weight0.20.51.60.3-0.6-0.70.0-0.90.50.5-1.0-0.60.61.3-1.30.0-0.0-0.7
Delta time in closed arm before/after self-admin1.11.02.9-0.6-0.7-1.0-1.70.9-1.3-1.3-0.11.2-1.2-1.31.3-0.10.1-0.3
Delta time in open arm before/after self-admin1.21.23.1-1.31.81.5-0.5-0.11.40.71.4-0.60.6-0.20.2-1.61.5-0.8
Diff in mean of infusions in LGA sessions0.81.03.41.5-0.30.21.8-0.0-0.00.3-0.9-0.10.1-0.10.11.6-1.61.7
Delay discount exponential model param0.20.30.7-0.5-0.7-0.9-0.60.0-0.4-0.6-0.80.5-0.5-0.30.30.3-0.2-0.3
Extinction: sum of active levers before priming1.41.56.5-2.50.80.4-1.90.9-0.3-0.70.60.5-0.5-0.80.8-1.71.7-1.5
Active lever presses in extinction session 60.70.71.60.7-0.4-0.30.51.3-1.0-0.9-0.41.0-1.0-0.60.60.8-0.91.1
Bone: final force1.01.53.2-1.81.61.3-0.8-0.31.51.00.9-1.11.10.6-0.6-1.81.7-1.2
Bone: final moment1.21.93.5-1.81.71.4-0.5-0.61.71.30.7-1.41.41.0-1.0-1.91.8-1.4
Food consumed during 24 hour testing period0.81.24.6-0.32.02.00.50.61.30.92.2-0.60.6-0.20.2-0.40.30.6
Glucose1.62.55.9-0.0-2.0-2.1-1.41.3-2.4-2.3-1.22.1-2.1-1.31.30.6-0.50.5
Heart weight1.11.75.10.20.91.11.6-1.01.11.7-0.3-1.61.62.2-2.2-0.40.3-0.4
Delay discount hyperbolic model param0.30.30.7-0.7-0.7-0.8-0.70.2-0.5-0.7-0.70.6-0.6-0.40.40.2-0.2-0.3
Intermittent access intake day 1-15 change0.71.45.30.3-2.2-2.3-1.0-1.0-1.2-0.8-2.20.5-0.5-0.10.10.2-0.0-0.7
Intermittent access intake escalation0.61.35.10.7-2.3-2.2-0.7-1.0-1.2-0.9-2.10.6-0.6-0.20.20.6-0.4-0.2
Intermittent access intake escalation 21.11.33.8-0.1-1.9-1.9-1.7-0.2-1.4-1.3-1.31.0-1.0-0.60.6-0.10.3-0.9
Intermitt. access day 1 inactive lever presses0.00.00.10.30.0-0.00.00.1-0.10.1-0.0-0.10.10.0-0.00.0-0.10.2
Intermitt. access day 15 inactive lever presses0.20.41.3-0.2-0.6-0.6-0.0-0.8-0.10.5-1.1-0.60.60.9-0.9-0.40.40.1
Intermitt. access escalation Index0.30.41.4-0.70.80.7-0.4-0.31.20.50.7-0.60.60.3-0.3-0.70.7-0.9
Intermittent access day 1 total infusions0.10.21.10.10.20.21.10.60.10.20.1-0.00.00.5-0.50.3-0.41.0
Intermittent access day 15 total infusions0.30.41.80.6-1.1-1.00.6-0.7-0.00.1-1.4-0.10.10.7-0.70.4-0.40.4
Intermittent access terminal intake (last 3 days)0.10.10.5-0.1-0.6-0.50.4-0.30.00.1-0.7-0.10.10.5-0.50.0-0.00.4
Intermittent access total infusions0.40.51.60.5-0.2-0.11.2-0.50.60.7-0.4-0.60.61.0-1.00.3-0.30.9
Intermittent access day 1 locomotion0.50.62.31.00.20.31.50.10.20.8-0.2-0.60.51.0-1.00.7-0.81.1
Intermittent access day 15 total locomotion1.01.95.70.3-0.3-0.31.7-1.60.61.6-1.9-1.61.52.4-2.40.0-0.00.3
Intermittent access total locomotion1.11.44.10.60.10.21.5-1.10.81.5-0.9-1.41.42.0-2.00.1-0.20.7
Intermittent access standard deviation0.20.52.10.0-1.3-1.4-0.8-0.3-0.9-0.6-1.00.4-0.40.1-0.1-0.30.4-0.5
Left kidney weight0.41.95.2-2.30.50.1-1.91.3-0.7-1.41.31.3-1.3-1.41.4-1.51.5-1.1
Right kidney weight0.52.56.7-2.60.4-0.0-2.22.1-0.9-1.81.11.8-1.8-1.41.4-1.51.5-1.1
Cocaine induced anxiety1.21.75.10.5-2.2-2.1-0.1-2.2-0.40.3-2.2-0.60.61.5-1.5-0.00.3-0.8
Post-drug Anxiety1.81.95.70.5-1.0-1.0-0.0-2.40.91.3-1.1-1.51.52.2-2.2-0.80.9-1.3
Baseline Anxiety1.01.12.90.41.31.40.5-0.41.71.30.9-1.21.21.3-1.3-0.60.5-0.6
Tail length1.76.726.6-5.23.83.0-1.91.61.3-0.02.7-0.00.1-1.51.5-3.93.7-1.5
Length with tail1.98.231.4-5.63.62.7-3.12.80.5-1.03.01.0-0.9-2.32.3-3.93.6-1.7
Length without tail0.61.95.8-1.61.31.1-1.42.4-0.7-1.31.81.4-1.4-1.71.7-0.70.50.3
Times rat made contact with spout1.41.64.9-0.51.81.80.11.80.1-0.42.20.7-0.6-1.81.80.3-0.41.3
Lifetime Intake0.40.51.80.3-0.4-0.30.9-0.80.50.8-0.6-0.80.81.3-1.3-0.00.00.4
Liver weight, left0.30.61.8-1.01.31.2-0.31.10.1-0.11.00.2-0.2-0.60.6-0.70.60.3
Liver weight, right0.61.02.6-0.30.60.5-0.61.6-0.4-1.11.41.2-1.2-1.51.50.2-0.30.7
Locomotor activity0.81.23.3-1.31.81.5-0.50.01.21.11.1-1.11.10.3-0.3-1.41.3-0.4
Locomotor testing distance0.71.22.2-1.00.90.8-0.2-1.21.31.40.1-1.51.51.1-1.1-1.31.3-0.9
Locomotor testing rearing0.20.40.7-0.60.80.80.1-0.50.60.70.2-0.80.80.4-0.4-0.80.8-0.3
Locomotion in novel chamber1.01.23.51.6-0.7-0.31.10.8-1.1-0.70.10.9-0.9-0.40.41.9-1.91.6
Locomotion in novel chamber post-restriction0.50.82.3-0.7-0.5-0.5-0.7-1.00.30.5-0.8-0.70.71.5-1.5-0.80.9-1.2
Fecal boli incidents, locomotor time 10.60.82.9-0.2-0.9-1.2-1.7-1.30.2-0.4-0.90.0-0.00.4-0.4-0.70.8-1.7
Change in fecal boli incidents, locomotor task1.41.43.61.0-1.6-1.20.51.0-1.9-1.1-0.81.2-1.2-0.70.71.4-1.31.1
Time >=10cm from walls, locomotor time 11.01.03.5-0.8-1.6-1.6-1.1-0.2-1.2-0.8-1.90.5-0.50.6-0.6-0.50.7-1.0
Bouts of movement, locomotor time 11.01.12.7-0.3-0.5-0.3-1.01.5-0.9-1.60.41.7-1.6-1.31.3-0.00.1-0.0
Total resting periods, locomotor time 10.60.71.9-0.5-0.5-0.4-1.11.0-0.7-1.40.21.3-1.3-0.80.8-0.40.4-0.4
Rest time, locomotor task time 10.50.61.70.4-1.3-1.2-0.90.2-0.8-1.2-0.61.0-1.0-0.30.30.10.0-0.5
Distance moved, locomotor task time 10.60.93.8-2.01.51.1-0.80.60.90.51.1-0.50.5-0.20.2-1.11.1-0.6
Vertical activity count, locomotor time 10.00.10.4-0.30.30.20.2-0.10.60.50.2-0.50.40.2-0.2-0.10.1-0.0
Time >=10cm from walls, locomotor time 20.81.12.3-0.90.1-0.1-0.9-1.10.70.9-0.7-1.11.11.3-1.3-1.51.5-1.4
Bouts of movement, locomotor time 20.81.35.22.3-0.10.42.20.2-0.70.3-0.4-0.10.10.0-0.01.5-1.61.8
Total resting periods, locomotor time 20.81.45.32.3-0.40.12.10.2-1.00.1-0.70.2-0.2-0.00.01.6-1.71.8
Rest time, locomotor task time 22.83.68.31.0-2.4-2.5-1.81.0-2.9-2.5-1.42.3-2.3-1.81.81.2-1.10.1
Distance moved, locomotor task time 22.93.56.6-2.62.11.7-0.3-0.92.61.90.9-1.91.91.6-1.6-2.42.3-1.6
Vertical activity count, locomotor time 21.11.64.0-1.10.80.60.4-1.22.01.4-0.3-1.41.41.7-1.7-1.11.1-1.0
Light reinforcement 13.27.918.7-3.14.23.7-0.6-1.04.32.73.0-2.72.70.9-0.9-3.43.2-1.7
Light reinforcement 22.13.37.6-1.82.31.90.2-1.52.72.21.2-2.22.21.1-1.1-2.22.1-1.0
Bone: marrow area1.32.97.9-0.80.0-0.1-0.72.8-2.5-2.30.12.4-2.4-2.32.30.5-0.60.4
Bone: maximum diameter2.24.19.7-0.9-0.2-0.5-1.43.1-2.6-2.90.22.9-2.9-2.92.90.5-0.50.4
Bone: maximum force0.20.41.8-1.30.70.6-0.40.00.50.30.2-0.40.40.3-0.3-1.11.1-0.7
Bone: maximum moment0.40.61.8-1.30.70.7-0.1-0.30.60.7-0.1-0.70.70.8-0.8-1.21.2-0.9
Mean time between licks in bursts0.61.55.50.3-2.3-2.3-0.70.2-1.5-1.2-2.00.9-1.00.3-0.30.5-0.4-0.7
Mean num. licks in bursts1.21.94.1-1.92.01.8-0.72.0-0.3-0.71.80.9-0.9-1.91.9-0.70.60.2
Cd content in liver0.50.61.4-1.20.80.6-0.80.9-0.3-0.31.20.3-0.3-0.60.6-1.00.9-0.5
Co content in liver1.11.32.9-1.61.31.2-0.31.7-0.4-0.91.61.1-1.0-1.51.5-0.50.30.4
Cu content in liver0.80.91.70.70.00.31.3-1.30.81.3-0.3-1.31.31.3-1.30.4-0.40.7
Fe content in liver0.30.40.90.6-0.7-0.60.80.6-0.9-0.5-1.00.6-0.60.3-0.30.7-0.7-0.1
K content in liver0.50.52.10.60.50.81.1-0.20.20.50.5-0.30.3-0.20.20.8-0.91.4
Mg content in liver1.11.13.80.61.31.71.50.60.50.31.5-0.00.0-0.70.71.0-1.11.9
Mn content in liver0.60.62.1-1.01.41.50.50.30.90.61.4-0.50.5-0.10.1-0.50.40.4
Na content in liver0.30.31.40.20.70.91.20.1-0.10.40.2-0.30.3-0.10.10.3-0.40.9
Rb content in liver1.41.64.7-2.21.91.7-1.00.60.70.31.9-0.20.3-0.40.4-1.81.7-0.9
Se content in liver0.10.10.40.50.30.40.00.2-0.00.10.3-0.10.1-0.30.30.6-0.60.4
Sr content in liver1.21.03.1-1.6-0.4-0.9-1.7-0.0-0.7-0.5-0.80.2-0.20.1-0.1-1.51.5-1.6
Zn content in liver0.40.41.30.9-0.20.00.30.20.0-0.3-0.00.4-0.4-0.70.71.2-1.11.0
Bone: minimum diameter1.73.29.4-1.10.20.0-1.23.1-2.1-2.40.72.5-2.5-2.52.50.0-0.10.3
Time in familiar zone, hab. session 10.20.20.4-0.6-0.3-0.4-0.50.5-0.5-0.6-0.50.6-0.6-0.30.3-0.20.2-0.4
Time in novel zone, hab. session 10.10.10.8-0.40.0-0.1-0.90.10.0-0.20.40.1-0.1-0.10.1-0.40.4-0.7
Total zone transitions, hab. session 10.91.33.61.9-1.3-0.91.5-0.3-0.5-0.2-1.30.3-0.3-0.10.11.7-1.61.6
Total locomotion distance, hab. session 11.52.16.32.5-2.2-1.71.3-1.2-0.6-0.1-1.80.1-0.10.6-0.62.1-2.01.2
Locomotion velocity, hab. session 11.11.65.22.3-1.7-1.21.4-1.0-0.30.0-1.30.0-0.00.3-0.32.0-1.91.5
Time in familiar zone, hab. session 20.30.31.20.10.80.80.80.80.30.10.30.1-0.1-0.40.40.6-0.71.1
Time in novel zone, hab. session 20.50.52.1-0.3-0.2-0.3-0.8-1.10.30.40.1-0.60.60.7-0.7-0.80.9-1.4
Total zone transitions, hab. session 21.01.33.01.3-0.10.21.7-1.61.11.4-0.6-1.31.31.1-1.10.8-0.81.0
Total locomotion distance, hab. session 21.21.64.31.9-0.7-0.41.4-2.10.81.3-0.8-1.31.31.3-1.31.1-1.10.7
Locomotion velocity, hab. session 21.21.65.11.7-0.8-0.51.2-2.30.81.4-1.0-1.51.41.6-1.60.8-0.80.5
Novel to familiar place preference ratio2.83.17.1-1.4-2.2-2.6-2.1-1.3-1.1-0.7-2.50.2-0.21.4-1.4-1.82.0-2.7
Novelty place preference3.03.37.4-1.7-2.3-2.7-2.3-1.0-1.4-1.0-2.60.5-0.51.1-1.1-1.92.1-2.7
Time in novel zone, NPP test2.62.86.3-1.4-2.2-2.5-2.0-1.0-1.2-0.9-2.50.4-0.41.2-1.2-1.71.9-2.5
Total zone transitions, NPP test1.72.47.62.6-0.20.42.8-1.41.01.5-0.5-1.31.31.1-1.11.9-1.91.9
Total locomotion distance, NPP test1.01.33.41.80.10.61.8-1.31.31.30.3-1.11.10.8-0.81.1-1.11.1
Locomotion velocity, NPP test0.81.12.21.40.20.61.5-1.41.41.30.3-1.21.20.9-0.90.7-0.70.7
Intraocular pressure0.70.92.80.00.10.10.6-1.20.81.4-0.4-1.41.41.7-1.7-0.30.4-0.3
Delta distance traveled before/after self-admin1.01.13.1-1.21.71.80.5-0.31.71.01.0-1.01.00.2-0.2-0.90.9-0.5
Delta ambulatory time before/after self-admin0.40.52.0-0.81.41.40.00.40.90.41.2-0.30.3-0.40.4-0.50.4-0.1
Parametrial fat weight0.30.72.10.1-0.5-0.5-0.81.5-1.1-1.10.31.1-1.1-0.70.70.6-0.60.5
Pavlov. Cond. lever latency0.40.51.7-0.7-0.1-0.3-1.30.4-0.8-0.70.60.6-0.6-0.40.4-0.91.0-1.0
Pavlov. Cond. magazine entry latency0.50.62.00.4-0.6-0.21.00.4-0.5-0.4-0.70.4-0.5-0.30.31.4-1.31.4
Pavlov. Cond. change in total contacts1.11.25.21.1-0.00.42.3-0.50.30.9-0.8-0.70.70.7-0.71.6-1.61.5
Pavlov. Cond. index score0.20.31.00.3-0.20.11.0-0.20.30.3-0.7-0.30.30.2-0.20.9-0.90.9
Pavlov. Cond. latency score0.10.10.5-0.1-0.10.10.6-0.10.30.2-0.6-0.20.20.1-0.10.5-0.50.7
Pavlov. Cond. lever contacts0.30.41.40.4-0.10.01.2-0.40.40.5-0.9-0.50.50.5-0.50.8-0.80.7
Pavlov. Cond. magazine entry number1.01.34.4-1.40.5-0.1-2.00.10.4-0.30.80.1-0.1-0.10.1-2.02.0-2.1
Pavlov. Cond. intertrial magazine entries1.11.34.3-0.22.11.8-0.10.01.71.12.0-1.01.0-0.00.0-0.80.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.90.7-0.20.11.4-0.30.30.4-0.8-0.30.30.2-0.21.2-1.21.3
Pavlov. Cond. response bias0.81.04.01.1-0.20.22.0-0.40.20.6-0.9-0.50.50.5-0.51.6-1.61.7
Pavlov. Cond. lever latency0.20.31.40.1-0.8-0.9-0.0-0.2-0.6-0.2-1.20.1-0.10.6-0.6-0.10.1-0.7
Pavlov. Cond. magazine entry latency0.70.91.51.00.91.21.1-0.91.21.21.2-1.11.10.4-0.40.4-0.50.5
Pavlov. Cond. change in total contacts0.20.40.70.80.60.80.6-0.60.80.80.8-0.70.70.1-0.10.3-0.30.8
Pavlov. Cond. index score0.30.41.30.70.70.90.5-0.30.80.61.1-0.50.5-0.30.30.5-0.50.7
Pavlov. Cond. latency score0.30.41.40.60.70.90.4-0.40.90.61.2-0.50.5-0.30.30.3-0.30.6
Pavlov. Cond. lever contacts0.20.21.3-0.20.70.9-0.00.10.50.21.1-0.10.1-0.50.5-0.10.00.5
Pavlov. Cond. magazine entry number0.81.02.6-0.6-0.5-0.7-0.61.6-1.3-1.5-0.51.5-1.5-0.90.90.0-0.00.2
Pavlov. Cond. intertrial magazine entries0.50.72.7-1.70.90.5-0.7-0.21.00.50.5-0.50.50.3-0.3-1.51.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.30.90.60.80.5-0.30.70.51.1-0.40.4-0.40.40.6-0.60.8
Pavlov. Cond. response bias0.10.20.50.10.50.60.2-0.40.60.50.7-0.40.4-0.10.10.1-0.10.3
Time in closed arm before self-admin1.11.44.21.50.30.92.0-1.01.51.30.1-1.21.21.3-1.30.8-0.71.0
Time in closed arm after self-admin0.50.51.31.1-0.9-0.51.0-0.8-0.10.3-1.0-0.30.30.7-0.70.7-0.70.2
Time in open arm before self-admin0.30.31.1-0.3-0.8-1.0-0.7-0.0-0.7-0.2-0.80.1-0.10.6-0.6-0.30.3-0.7
Time in open arm after self-admin1.71.84.5-1.91.81.5-1.51.70.4-0.52.10.6-0.6-1.41.4-1.41.3-0.4
Bone: periosteal estimation1.22.67.5-1.00.30.1-0.82.7-2.1-2.10.42.2-2.2-2.22.20.2-0.30.2
Bone: periosteal perimeter1.01.75.1-1.51.00.8-0.52.3-0.9-1.40.81.6-1.5-1.91.9-0.30.20.2
Bone: post-yield work1.52.23.60.7-0.8-0.60.71.8-1.9-1.7-0.11.9-1.9-1.71.71.5-1.51.6
Progressive ratio test 1 active lever presses0.10.10.70.10.20.20.60.7-0.20.10.10.1-0.10.2-0.20.3-0.40.8
Progressive ratio test 1 breakpoint0.10.10.5-0.00.20.20.50.7-0.20.00.10.1-0.10.3-0.30.2-0.30.7
Progressive ratio test 1 inactive lever presses0.00.10.3-0.5-0.3-0.30.20.0-0.3-0.0-0.60.0-0.00.3-0.3-0.00.00.1
Progressive ratio test 2 active lever presses1.51.75.10.40.81.02.3-1.01.31.80.2-1.61.61.8-1.80.3-0.41.1
Progressive ratio test 2 breakpoint1.61.95.70.50.81.12.4-1.01.41.90.3-1.71.71.8-1.80.4-0.51.2
Progressive ratio test 2 inactive lever presses0.20.31.5-0.2-0.5-0.41.2-0.2-0.30.0-0.60.0-0.00.1-0.10.6-0.61.2
Incentive Sensitization - Responses2.63.77.70.21.51.72.7-2.12.42.80.7-2.62.62.4-2.4-0.10.00.8
Incentive Sensitization - Breakpoint3.24.18.70.31.61.82.9-2.22.53.00.7-2.72.72.5-2.5-0.0-0.00.8
Sum of active levers in priming session hrs 5-60.80.72.00.80.60.81.21.4-0.7-0.30.40.5-0.5-0.80.80.8-0.91.4
Progressive ratio0.81.22.9-0.60.70.80.8-1.51.71.40.2-1.41.41.2-1.2-0.80.8-0.6
Food seeking constrained by brief footshock1.41.83.61.50.30.61.2-1.41.71.9-0.2-1.81.81.9-1.90.3-0.30.2
Seeking ratio, punishment vs. effort0.20.31.41.20.00.10.20.6-0.2-0.00.20.1-0.1-0.20.20.8-0.80.8
Retroperitoneal fat weight0.20.83.3-0.0-1.2-1.3-0.6-1.20.00.3-1.8-0.50.51.0-1.00.3-0.2-0.3
Reaction time number correct0.91.76.70.4-0.8-0.70.3-2.61.21.4-1.0-1.61.61.9-1.90.00.1-0.8
Reaction time mean minus median0.40.91.81.3-1.3-1.11.2-0.5-1.1-0.3-1.10.3-0.30.3-0.31.2-1.21.1
Reaction time mean minus median AUC0.40.92.11.3-1.3-1.01.4-1.1-0.80.1-1.1-0.10.10.7-0.71.0-1.00.9
Reaction time num false alarms1.52.24.61.50.40.71.8-2.11.82.1-0.1-2.02.01.6-1.60.5-0.50.9
Reaction time num false alarms AUC1.82.86.51.60.40.82.1-2.62.02.4-0.2-2.32.31.8-1.80.5-0.51.0
Reaction time trials correct on left0.91.76.70.4-0.8-0.70.3-2.61.21.4-1.0-1.61.61.9-1.90.00.1-0.8
Reaction time trials on left0.91.76.70.6-0.9-0.70.4-2.61.11.4-1.1-1.51.51.9-1.90.2-0.0-0.6
Reaction time mean0.81.35.71.9-0.6-0.22.4-0.2-0.70.3-0.7-0.10.10.6-0.61.5-1.61.6
Reaction time mean AUC0.91.45.32.1-0.9-0.42.3-0.1-0.90.0-0.80.2-0.20.3-0.31.8-1.81.7
Median of all reaction times0.81.15.21.9-0.30.02.3-0.1-0.50.4-0.5-0.20.20.6-0.61.4-1.41.4
Reaction time omissions3.24.712.73.2-2.1-1.52.50.8-2.0-1.0-1.81.2-1.3-0.60.63.6-3.63.1
Reaction time false alarm rate1.01.43.21.10.91.21.8-1.21.41.70.3-1.51.50.9-0.90.3-0.31.1
Reaction time premature initiation rate0.71.03.6-0.5-0.2-0.1-0.11.7-1.9-1.1-0.41.2-1.2-1.01.00.5-0.51.3
Reaction time premature initiations0.20.31.3-0.3-0.6-0.5-0.10.3-1.2-0.4-0.80.4-0.4-0.10.10.5-0.40.8
Std. dev. reaction times0.91.74.72.1-1.4-1.02.2-0.7-1.00.2-1.3-0.00.00.7-0.71.8-1.81.6
Reaction time trials completed0.91.76.70.6-0.9-0.70.4-2.61.11.4-1.1-1.51.51.9-1.90.2-0.0-0.6
Reaction time trials AUC0.91.76.70.6-0.8-0.70.3-2.61.21.4-1.0-1.61.61.9-1.90.10.0-0.6
Run reversals in cocaine runway, females0.60.62.7-1.60.40.5-0.6-0.50.20.10.4-0.30.3-0.00.0-1.21.2-1.4
Run reversals in cocaine runway, males0.30.30.91.00.40.50.5-0.30.30.40.1-0.30.30.1-0.10.7-0.80.6
Latency to leave start box in cocaine runway0.81.03.21.6-0.30.01.80.2-0.1-0.0-0.40.2-0.2-0.20.21.6-1.71.6
Latency to leave start box in cocaine runway, F0.30.31.10.50.30.40.90.50.3-0.20.10.3-0.3-0.40.41.0-1.00.7
Latency to leave start box in cocaine runway, M1.31.24.12.0-1.4-1.11.10.2-1.1-0.5-0.90.6-0.6-0.10.11.5-1.51.6
Std. dev. time between licks in bursts0.70.93.61.1-1.9-1.60.1-0.4-1.3-0.6-1.40.4-0.40.4-0.40.9-0.7-0.4
Total sessions with >9 infusions0.20.31.3-0.10.00.10.4-0.40.30.6-0.4-0.60.61.2-1.2-0.30.2-0.4
Short access day 1 total inactive lever presses0.40.51.2-0.5-0.2-0.40.2-1.10.50.7-0.4-0.90.81.1-1.1-0.70.7-0.2
Short access day 10 total inactive lever presses0.20.41.60.7-0.3-0.30.6-1.30.30.7-0.6-0.80.80.7-0.70.1-0.10.1
Short access day 1 total infusions0.20.20.8-0.80.20.1-0.3-0.10.10.10.4-0.20.20.4-0.4-0.80.8-0.9
Short access day 10 total infusions0.30.40.9-0.1-0.7-0.70.30.7-0.8-0.7-0.50.7-0.7-0.20.20.5-0.51.0
Short access total infusions0.20.20.9-0.0-0.7-0.60.4-0.5-0.10.2-0.6-0.30.31.0-1.0-0.10.10.0
Short access day 1 locomotion0.20.30.80.4-0.8-0.80.2-0.2-0.8-0.4-0.90.3-0.30.2-0.20.4-0.4-0.1
Short access day 10 total locomotion0.20.41.70.0-0.5-0.6-0.20.1-0.60.2-0.9-0.30.31.3-1.3-0.30.3-0.1
Short access total locomotion0.80.93.9-0.0-0.3-0.30.4-0.90.20.9-1.2-1.01.02.0-2.0-0.50.5-0.6
One hour access (0.3 mA shock)0.91.12.4-1.30.60.3-0.6-0.80.70.9-0.1-1.11.11.1-1.1-1.51.5-1.5
Compulsive drug intake0.60.72.8-0.21.61.50.00.10.80.71.7-0.60.60.2-0.2-0.60.5-0.4
One hour access (shock baseline)0.60.92.1-1.3-0.5-0.8-0.4-1.00.40.5-1.4-0.70.71.2-1.2-1.11.2-1.1
Social response proportion0.40.51.3-0.2-0.3-0.4-0.31.0-1.1-0.9-0.01.0-1.0-0.90.90.1-0.10.2
Social responses0.10.21.1-0.40.0-0.2-1.0-0.30.3-0.1-0.2-0.00.0-0.30.3-0.40.5-0.8
Social time0.30.40.90.2-0.3-0.4-0.51.0-0.5-0.90.21.0-0.9-0.50.50.0-0.0-0.6
Soleus weight1.23.615.3-1.23.63.60.01.02.21.03.9-0.60.7-1.11.1-1.00.80.6
Bone: stiffness0.10.10.5-0.4-0.2-0.20.3-0.30.10.1-0.7-0.20.20.5-0.5-0.30.30.1
Tibialis anterior weight1.44.612.4-1.33.53.50.3-0.93.22.32.8-2.22.20.8-0.8-2.01.8-0.8
Time to tail flick, vehicle, before self-admin0.40.51.31.1-0.9-0.60.6-0.80.40.2-0.9-0.30.30.7-0.70.8-0.80.2
Time to tail flick, vehicle, after self-admin0.60.72.41.0-1.5-1.40.2-0.8-0.6-0.2-1.50.1-0.10.4-0.41.1-1.00.0
Time to tail flick, test, before self-admin0.60.62.00.3-1.4-1.4-0.5-0.6-0.0-0.7-1.30.6-0.6-0.50.50.7-0.5-0.4
Time to tail flick, test, after self-admin0.80.81.40.8-1.1-1.1-0.70.4-0.9-1.20.11.1-1.1-1.11.11.0-0.90.1
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.1-0.0-0.3-0.50.2-0.3-0.30.20.3-0.3-0.60.60.1-0.10.1
Delta time to tail flick, test, before/after SA0.10.10.60.30.00.1-0.20.2-0.2-0.10.80.1-0.10.0-0.00.1-0.10.0
Tibia length1.13.09.2-2.7-0.1-0.7-2.3-1.00.40.2-0.8-0.60.61.1-1.1-3.03.0-3.0
Ambulatory time before self-admin0.81.22.60.90.30.51.6-1.31.11.5-0.4-1.41.41.6-1.6-0.10.10.1
Ambulatory time after self-admin1.61.94.20.31.61.91.8-1.02.11.90.8-1.81.81.2-1.2-0.30.30.3
Bone: tissue strength1.21.33.00.40.70.91.1-1.41.41.70.3-1.61.61.2-1.2-0.0-0.00.7
Total heroin consumption1.21.45.60.9-0.10.31.51.2-0.6-0.70.01.0-1.0-1.11.11.6-1.72.4
Bone: trabecular number0.20.41.50.10.60.81.2-0.40.50.80.3-0.70.70.7-0.7-0.0-0.00.6
Bone: trabecular spacing1.21.64.1-1.21.20.9-1.2-0.92.01.01.0-1.21.20.7-0.7-1.61.6-1.9
Bone: trabecular thickness0.30.31.50.1-0.6-0.60.40.4-1.2-0.5-1.10.5-0.5-0.10.10.3-0.30.2
Bone: trabecular tissue density1.01.54.5-0.50.20.0-1.51.7-0.3-1.50.91.5-1.5-2.12.1-0.20.20.2
Water consumed over 24 hours1.31.86.6-0.52.52.60.70.91.21.02.4-0.60.6-0.90.9-0.0-0.11.3
Number of responses in last shaping day0.30.31.3-1.10.1-0.1-0.70.7-0.2-0.50.40.5-0.5-0.50.5-0.60.6-0.1