Hub : Genes

LOC120103526

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC120103526 0.15 0.1 5.5e-03 0.01 0.05 -0.01 0.04 1.7e-01 2.5e-02 7.2e-01 4.0e-02
2 PL gene expression LOC120103526 0.04 0.03 1.6e-03 0.03 0.02 0.02 0.02 5.0e-04 3.2e-03 9.8e-04 2.4e-03
3 NAcc gene expression LOC120103526 0.07 0.04 5.5e-06 0.04 0.03 0.04 0.04 1.9e-07 8.6e-06 3.3e-07 3.4e-07
4 Adipose isoform ratio XR_005505905.2 0.2 0.1 8.6e-05 0.04 0.03 0.03 0.03 2.2e-05 7.8e-04 9.2e-05 1.6e-04
5 pVTA gene expression LOC120103526 0.38 0.14 8.8e-06 0.04 0.06 0.06 0.03 1.7e-04 7.7e-06 1.1e-05 2.2e-03
6 Adipose gene expression LOC120103526 0.09 0.04 5.2e-10 0.09 0.09 0.08 0.09 2.4e-10 3.9e-10 1.8e-09 9.1e-10
7 Liver gene expression LOC120103526 0.05 0.03 7.2e-05 0.04 0.03 0.04 0.04 2.2e-05 1.2e-04 4.5e-05 2.4e-05
8 NAcc isoform ratio XR_005505905.2 0.13 0.06 5.5e-06 0.04 0.04 0.03 0.04 9.9e-07 3.9e-07 1.3e-05 1.3e-06
9 Brain gene expression LOC120103526 0.06 0.04 2.1e-04 0.03 0.04 0.03 0.04 5.7e-04 5.6e-05 7.2e-04 6.3e-05
10 pVTA isoform ratio XR_005505905.2 0.04 0.03 3.7e-03 0.03 0.02 0.02 0.01 1.0e-03 8.3e-03 9.7e-03 3.0e-02
11 IL gene expression LOC120103526 0.57 0.14 2.7e-03 0.06 0.05 -0 -0.01 1.8e-02 2.6e-02 3.9e-01 6.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.11.83.70.91.61.5-1.51.61.41.4-1.90.6-0.90.8
Area under the delay curve0.10.20.8-0.2-0.2-0.30.3-0.1-0.4-0.40.00.10.9-0.7
BMI with tail0.20.94.7-1.5-0.5-0.50.50.8-0.5-0.50.5-2.20.4-0.4
BMI without tail0.20.73.1-0.20.0-0.10.11.7-0.2-0.30.5-1.80.8-0.6
Body weight0.62.611.31.71.71.6-1.63.41.71.5-1.1-0.40.1-0.0
Weight adjusted by age0.10.21.20.40.40.2-0.21.10.30.3-0.2-0.20.3-0.3
Bone surface1.62.94.51.81.92.0-1.92.11.71.7-2.11.1-0.80.7
Bone volume0.91.62.61.11.61.5-1.51.51.31.3-1.60.4-0.80.6
Breakpoint value in progressive ratio session3.13.75.32.02.12.1-2.12.32.12.1-2.01.3-1.31.3
Number of licking bursts0.30.41.6-0.3-0.9-0.70.7-1.3-0.6-0.60.70.30.4-0.3
Context. condit. distance diff. score0.60.72.40.90.70.9-0.91.50.50.7-0.70.3-0.70.7
Locomotion velocity, session 10.70.81.4-1.0-0.9-0.80.9-1.2-0.7-0.81.2-1.10.4-0.2
Locomotion distance, session 10.50.61.0-0.8-1.0-0.80.9-0.7-0.9-0.80.9-0.50.6-0.6
Locomotion velocity, session 20.80.93.3-0.8-0.9-1.11.2-1.8-0.9-1.00.9-0.10.2-0.2
Locomotion distance, session 20.40.51.5-0.7-0.9-0.80.8-1.2-0.8-0.70.7-0.20.2-0.2
Locomotion velocity, session 30.20.31.00.60.40.3-0.20.90.20.3-0.61.00.1-0.1
Locomotion distance, session 31.51.64.51.21.31.2-1.22.11.21.3-1.51.4-0.40.4
Stereotopy head waving bouts, day 31.51.82.5-1.2-1.6-1.41.4-0.9-1.4-1.31.4-1.31.2-1.5
Stereotopy head waving duration, day 30.60.72.6-0.7-0.9-0.90.8-1.6-0.7-0.70.8-0.30.3-0.7
Locomotion velocity, session 70.80.92.60.60.70.7-0.81.60.80.7-1.51.30.1-0.2
Locomotion distance, session 70.81.14.70.70.80.5-0.62.20.70.7-1.41.10.7-0.8
Stereotopy head waving bouts, day 70.00.10.2-0.1-0.4-0.20.20.2-0.2-0.00.1-0.20.3-0.4
Stereotopy head waving duration, day 70.30.30.6-0.7-0.7-0.60.6-0.7-0.5-0.50.5-0.40.2-0.4
Locomotion velocity, session 80.81.04.8-0.8-0.6-0.60.6-2.2-0.6-0.60.9-0.3-1.21.2
Locomotion distance, session 80.30.41.40.50.40.6-0.60.30.20.4-0.40.4-1.11.2
Degree of sensitization distance0.00.00.20.20.0-0.0-0.00.00.1-0.1-0.20.40.1-0.1
Degree of sensitization stereotypy0.10.10.20.40.20.3-0.30.10.30.4-0.30.3-0.50.5
Conditioned locomotion11.613.418.7-3.3-3.9-4.04.1-3.4-4.0-3.94.3-3.32.9-2.8
Cocaine response after cond. corrected0.40.50.90.50.80.4-0.40.90.70.7-0.80.9-0.60.7
Cocaine response after cond. not corrected0.70.81.90.51.00.6-0.71.40.90.9-1.30.9-0.70.8
Cocaine response before conditioning0.60.72.60.60.60.7-0.71.60.50.6-1.40.80.4-0.3
Saline control response0.50.62.71.10.50.7-0.71.60.60.6-0.50.30.8-0.6
Bone: connectivity density2.64.16.51.62.32.3-2.41.82.22.3-2.51.3-1.61.4
Bone: cortical apparent density0.30.51.2-1.1-0.5-0.70.8-0.2-0.8-0.70.6-0.90.2-0.2
Bone: cortical area1.11.62.61.61.61.5-1.40.71.21.2-0.90.9-1.31.4
Bone: cortical porosity0.10.10.4-0.2-0.3-0.40.4-0.4-0.3-0.30.6-0.10.1-0.0
Bone: cortical porosity0.00.00.30.50.10.10.00.10.00.10.30.30.1-0.0
Bone: cortical thickness0.30.41.40.40.80.6-0.70.10.60.5-0.2-0.2-1.01.2
Bone: cortical thickness0.50.61.0-1.0-0.4-0.70.8-1.0-0.9-0.70.9-0.9-0.30.5
Bone: cortical tissue density0.30.41.2-1.1-0.5-0.70.8-0.2-0.7-0.70.6-0.80.2-0.2
Condit. Reinf. active minus inactive responses2.73.06.02.51.51.9-1.81.01.71.7-1.72.2-1.31.3
Condit. Reinf. active-inactive response ratio1.92.14.02.01.31.6-1.61.71.41.4-1.41.7-0.60.5
Condit. Reinf. active responses4.45.49.33.02.12.6-2.40.32.22.3-2.02.7-2.42.5
Condit. Reinf. inactive responses1.11.44.11.10.81.0-0.9-1.50.80.9-0.30.8-1.82.0
Incentive salience index mean4.75.89.03.02.22.7-2.60.52.42.4-2.32.9-2.22.4
Condit. Reinf. lever presses4.15.78.22.52.22.7-2.60.12.42.3-2.52.9-2.32.5
Condit. Reinf. active minus inactive responses1.01.33.01.50.81.0-1.0-0.71.00.9-0.91.7-1.41.3
Condit. Reinf. active-inactive response ratio0.20.20.70.7-0.3-0.20.2-0.8-0.2-0.20.40.7-0.10.2
Condit. Reinf. active responses2.13.05.81.81.51.6-1.8-0.51.91.6-1.82.4-1.91.7
Condit. Reinf. inactive responses1.82.34.01.01.61.6-1.70.71.91.6-2.01.7-1.31.0
Condit. Reinf. lever presses1.21.72.71.31.41.4-1.60.01.61.5-1.41.1-1.10.9
Condit. Reinf. lever reinforcers received3.54.96.92.22.12.2-2.4-0.22.52.2-2.22.6-2.42.3
Conditioned reinforcement - actives1.32.34.12.01.71.6-1.50.61.71.7-1.21.7-1.21.2
Conditioned reinforcement - inactives1.21.75.02.21.41.4-1.40.41.31.4-0.71.2-1.01.0
Conditioned locomotion1.21.52.11.41.41.4-1.4-0.01.31.4-0.70.8-1.51.3
Patch foraging indifference point 0 sec2.54.67.32.72.52.3-2.21.22.32.3-2.02.4-1.41.6
Patch foraging indifference point AUC2.02.95.11.81.81.9-1.8-0.61.71.7-1.11.5-2.32.1
Delay disc. indifference point, 0s delay0.10.10.50.20.50.2-0.4-0.70.30.30.00.0-0.20.2
Delay disc. indifference point, 16s delay0.40.40.70.70.80.6-0.60.70.60.7-0.70.6-0.10.3
Delay disc. indifference point, 2s delay0.10.21.00.00.1-0.20.20.3-0.1-0.30.1-0.01.0-0.7
Delay disc. indifference point, 24s delay0.10.20.6-0.3-0.3-0.30.4-0.8-0.4-0.40.4-0.10.4-0.4
Delay disc. indifference point, 4s delay1.31.31.8-1.3-1.2-1.31.2-1.1-1.3-1.31.1-0.81.1-0.9
Delay disc. indifference point, 8s delay0.20.21.00.00.00.1-0.11.00.00.0-0.80.40.7-0.5
Indifference point function ln k0.40.72.2-0.5-0.4-0.50.41.5-0.3-0.3-0.2-0.61.4-1.3
Indifference point function log k0.40.72.2-0.5-0.4-0.50.41.5-0.3-0.3-0.2-0.61.4-1.3
Patch foraging total patch changes 0 sec2.24.27.02.62.42.2-2.21.22.32.3-1.82.2-1.31.5
Patch foraging total patch changes 12 sec1.31.73.21.81.41.4-1.3-0.31.21.2-0.61.4-1.41.6
Patch foraging total patch changes 18 sec0.60.92.21.51.21.0-0.9-0.11.11.0-0.61.3-0.50.6
Patch foraging total patch changes 24 sec1.32.23.61.81.71.4-1.3-0.41.61.5-0.91.9-1.51.6
Patch foraging total patch changes 6 sec3.96.07.82.62.72.6-2.60.42.62.6-2.02.4-2.72.8
Patch foraging time to switch 0 sec5.611.415.8-4.0-3.7-3.83.8-1.8-3.7-3.73.1-3.42.8-2.7
Patch foraging water rate 0 sec2.24.77.82.82.42.5-2.42.52.32.4-2.01.8-1.01.0
Patch foraging water rate 12 sec2.55.37.52.62.72.4-2.42.72.62.5-2.21.7-1.41.6
Patch foraging water rate 18 sec0.40.62.50.70.70.7-0.71.60.60.6-0.80.3-0.20.3
Patch foraging water rate 24 sec0.60.85.60.40.60.6-0.72.40.60.7-0.9-0.10.3-0.0
Patch foraging water rate 6 sec1.72.53.61.41.71.7-1.81.91.71.7-1.50.7-1.31.3
Seeking ratio, delayed vs. immediate footshock0.91.12.3-1.5-1.1-1.31.10.2-1.0-1.10.4-0.71.1-1.1
Distance traveled before self-admin0.30.31.51.20.10.2-0.20.30.10.1-0.21.20.5-0.6
Distance traveled after self-admin0.40.41.41.2-0.3-0.00.21.0-0.2-0.30.30.90.8-0.8
Extensor digitorum longus weight0.52.15.72.41.81.5-1.52.31.21.2-0.50.10.7-0.8
Bone: elastic displacement0.70.81.9-1.0-0.9-0.90.7-0.9-0.9-0.91.2-1.40.4-0.4
Bone: elastic work0.30.40.80.90.90.7-0.80.70.70.7-0.3-0.1-0.50.4
Bone: endosteal estimation0.30.72.81.70.60.7-0.61.10.50.5-0.51.20.4-0.5
Bone: endosteal perimeter1.12.46.02.41.61.6-1.50.91.51.4-1.42.4-0.80.8
Epididymis fat weight0.72.56.9-1.0-1.0-1.01.02.4-0.8-0.80.2-1.52.6-2.6
Delta time in closed arm before/after self-admin0.90.82.8-0.90.10.3-0.2-1.70.10.1-0.1-0.5-1.51.6
Delta time in open arm before/after self-admin0.70.71.3-0.1-0.8-0.80.80.4-0.9-0.81.1-0.81.1-1.1
Diff in mean of infusions in LGA sessions0.00.00.10.3-0.2-0.20.10.3-0.1-0.1-0.10.40.10.1
Delay discount exponential model param0.30.31.10.50.50.6-0.60.30.60.6-0.20.1-1.00.8
Extinction: sum of active levers before priming1.51.72.50.91.31.5-1.50.81.41.3-1.60.9-1.41.4
Active lever presses in extinction session 62.22.24.80.91.61.5-1.5-0.31.41.5-1.30.9-2.22.2
Bone: final force0.20.31.80.80.60.5-0.31.30.20.2-0.30.1-0.0-0.1
Bone: final moment0.20.31.80.80.60.6-0.51.40.30.3-0.40.1-0.1-0.1
Food consumed during 24 hour testing period1.01.43.2-0.1-1.2-1.21.1-0.8-1.0-1.11.8-0.91.4-1.4
Glucose1.11.74.80.51.11.4-1.40.71.11.4-0.8-0.4-2.21.9
Heart weight0.10.20.70.4-0.00.3-0.20.8-0.10.0-0.1-0.80.5-0.4
Delay discount hyperbolic model param0.30.31.20.40.50.6-0.60.30.60.6-0.2-0.0-1.10.8
Intermittent access intake day 1-15 change0.91.94.21.71.31.5-1.42.11.31.3-1.41.6-0.10.1
Intermittent access intake escalation0.71.42.71.61.21.3-1.21.61.11.2-1.21.5-0.20.0
Intermittent access intake escalation 22.12.44.92.21.61.6-1.61.51.41.6-1.62.2-0.40.3
Intermitt. access day 1 inactive lever presses0.10.41.5-0.3-0.00.2-0.0-1.20.00.00.2-0.3-1.21.1
Intermitt. access day 15 inactive lever presses0.10.10.4-0.30.10.2-0.2-0.5-0.10.1-0.3-0.2-0.70.6
Intermitt. access escalation Index1.82.53.5-1.6-1.6-1.61.7-0.6-1.5-1.61.6-1.61.8-1.9
Intermittent access day 1 total infusions0.91.43.9-1.3-1.1-1.21.1-2.0-1.1-1.11.4-1.30.00.0
Intermittent access day 15 total infusions0.00.10.40.0-0.1-0.10.2-0.4-0.2-0.10.6-0.20.2-0.2
Intermittent access terminal intake (last 3 days)0.00.10.30.20.10.1-0.1-0.20.00.10.5-0.3-0.10.1
Intermittent access total infusions0.40.51.6-0.4-0.4-0.50.5-1.3-0.4-0.41.2-0.9-0.20.3
Intermittent access day 1 locomotion0.30.43.0-0.3-0.2-0.30.2-1.7-0.2-0.20.6-0.3-0.70.7
Intermittent access day 15 total locomotion0.20.30.60.70.70.7-0.7-0.20.40.7-0.20.2-0.70.7
Intermittent access total locomotion0.40.51.30.50.70.6-0.6-0.60.60.7-0.0-0.0-1.11.1
Intermittent access standard deviation0.30.61.00.91.00.9-0.90.40.81.0-0.80.6-0.30.5
Left kidney weight0.52.14.52.11.71.7-1.71.71.51.5-0.90.7-0.70.8
Right kidney weight0.10.73.41.00.90.5-0.51.80.50.5-0.1-0.50.7-0.6
Cocaine induced anxiety0.30.41.30.4-0.3-0.30.30.3-0.3-0.3-0.30.91.1-1.0
Post-drug Anxiety0.30.31.20.70.30.3-0.3-0.80.30.3-0.41.1-0.30.5
Baseline Anxiety1.21.44.30.11.01.0-1.0-0.71.01.0-0.90.3-2.02.1
Tail length0.83.010.92.91.71.5-1.53.31.41.4-0.90.90.7-0.5
Length with tail2.08.819.84.43.23.2-3.14.03.13.1-2.42.1-0.80.9
Length without tail0.82.74.12.01.92.0-1.91.92.01.9-1.50.9-0.60.5
Times rat made contact with spout5.76.69.8-2.2-2.8-2.72.7-0.3-2.7-2.82.4-2.23.1-3.0
Lifetime Intake0.30.31.20.00.0-0.10.1-1.1-0.00.00.9-0.7-0.60.7
Liver weight, left0.30.42.1-0.9-0.2-0.40.40.5-0.2-0.40.4-1.40.7-0.5
Liver weight, right1.11.94.7-1.7-1.4-1.41.3-0.1-1.2-1.31.3-2.21.3-1.0
Locomotor activity13.921.727.74.85.35.2-5.23.45.25.2-4.94.0-3.83.8
Locomotor testing distance10.819.526.14.35.04.9-4.93.05.15.0-4.73.7-3.63.6
Locomotor testing rearing6.513.218.73.44.24.2-4.12.14.34.3-3.52.6-3.23.2
Locomotion in novel chamber0.20.30.4-0.3-0.6-0.60.50.4-0.5-0.50.7-0.40.6-0.6
Locomotion in novel chamber post-restriction0.30.42.6-0.1-0.3-0.40.3-1.6-0.3-0.40.11.0-0.60.4
Fecal boli incidents, locomotor time 11.72.46.52.31.61.5-1.52.51.71.5-1.21.20.10.1
Change in fecal boli incidents, locomotor task0.20.21.0-0.5-0.20.10.2-1.0-0.3-0.2-0.20.0-0.80.6
Time >=10cm from walls, locomotor time 11.41.52.7-1.2-1.2-1.11.1-0.0-1.1-1.21.2-1.41.4-1.6
Bouts of movement, locomotor time 11.41.55.4-0.3-1.2-1.11.2-1.4-1.2-1.22.3-1.30.7-0.9
Total resting periods, locomotor time 11.92.16.7-0.5-1.4-1.21.4-1.7-1.4-1.42.6-1.50.9-1.1
Rest time, locomotor task time 10.30.31.30.9-0.3-0.20.3-1.2-0.2-0.30.90.50.4-0.4
Distance moved, locomotor task time 10.10.10.6-0.8-0.0-0.00.10.1-0.2-0.2-0.4-0.4-0.40.4
Vertical activity count, locomotor time 10.10.31.5-0.10.40.5-0.41.20.30.3-0.7-0.3-0.10.0
Time >=10cm from walls, locomotor time 22.53.65.1-1.4-2.0-1.92.0-0.6-2.0-2.02.2-1.92.2-2.2
Bouts of movement, locomotor time 20.40.61.9-0.9-0.5-0.60.60.7-0.6-0.60.1-0.21.4-1.3
Total resting periods, locomotor time 20.50.92.2-1.1-0.8-0.90.90.6-0.9-0.90.4-0.51.5-1.5
Rest time, locomotor task time 20.50.71.5-0.3-0.8-0.90.8-0.2-0.8-0.81.2-0.81.0-1.1
Distance moved, locomotor task time 20.00.00.10.00.10.2-0.1-0.0-0.00.1-0.30.1-0.20.3
Vertical activity count, locomotor time 20.30.51.7-0.2-0.3-0.20.21.3-0.3-0.2-0.2-0.21.2-1.2
Light reinforcement 10.30.73.00.2-0.5-0.60.60.5-0.5-0.60.40.41.7-1.6
Light reinforcement 20.71.12.0-1.0-1.1-1.11.1-1.4-1.2-1.10.80.11.0-1.0
Bone: marrow area0.40.93.41.80.80.9-0.71.30.70.7-0.71.40.3-0.4
Bone: maximum diameter2.85.210.43.22.72.4-2.30.62.22.2-1.92.8-1.81.9
Bone: maximum force0.61.14.21.41.21.1-1.02.00.90.8-0.90.4-0.20.1
Bone: maximum moment0.71.14.11.41.21.2-1.02.00.90.9-0.90.3-0.20.1
Mean time between licks in bursts0.10.20.7-0.1-0.5-0.30.30.5-0.4-0.40.8-0.80.1-0.2
Mean num. licks in bursts0.91.32.7-0.8-0.7-0.80.91.5-0.9-1.00.6-1.51.6-1.6
Cd content in liver0.10.10.4-0.30.20.1-0.10.60.40.2-0.5-0.20.0-0.2
Co content in liver4.75.48.22.92.52.6-2.61.82.62.5-2.22.4-1.61.5
Cu content in liver0.30.40.6-0.7-0.7-0.80.7-0.3-0.6-0.80.6-0.20.7-0.6
Fe content in liver0.50.52.81.30.50.5-0.50.10.50.5-0.51.7-0.00.1
K content in liver0.30.31.7-0.10.10.2-0.2-0.50.30.3-0.71.3-0.80.6
Mg content in liver0.20.21.10.20.10.2-0.2-0.00.30.3-0.51.0-0.50.4
Mn content in liver1.61.74.7-0.5-1.2-1.41.4-0.0-1.2-1.31.10.52.1-2.2
Na content in liver0.10.10.4-0.50.0-0.20.1-0.6-0.0-0.1-0.60.50.1-0.2
Rb content in liver1.92.33.7-1.3-1.9-1.81.7-0.8-1.6-1.51.6-1.11.4-1.5
Se content in liver0.30.42.2-0.0-0.4-0.30.4-1.2-0.4-0.5-0.01.50.1-0.1
Sr content in liver0.10.00.1-0.30.1-0.0-0.10.20.30.2-0.2-0.30.1-0.3
Zn content in liver0.40.41.60.50.30.2-0.2-1.00.40.3-0.31.3-0.80.9
Bone: minimum diameter1.01.93.61.91.51.5-1.51.01.41.3-1.21.7-0.91.0
Time in familiar zone, hab. session 10.20.21.00.50.30.3-0.31.00.30.3-0.20.0-0.1-0.0
Time in novel zone, hab. session 10.10.10.3-0.40.0-0.0-0.0-0.60.10.0-0.20.2-0.40.5
Total zone transitions, hab. session 10.81.11.9-1.4-1.2-1.11.1-1.4-1.1-1.10.8-0.70.8-0.7
Total locomotion distance, hab. session 10.50.71.2-1.0-0.8-1.00.9-0.4-1.1-1.00.5-0.31.1-0.9
Locomotion velocity, hab. session 10.81.11.8-0.9-1.1-1.21.2-1.1-1.3-1.20.9-0.41.1-0.9
Time in familiar zone, hab. session 20.70.82.2-1.1-0.6-0.80.80.7-0.6-0.70.6-1.50.9-0.8
Time in novel zone, hab. session 20.91.02.11.40.81.0-1.0-0.50.80.9-0.41.3-1.10.9
Total zone transitions, hab. session 20.20.21.4-0.5-0.5-0.30.3-1.2-0.4-0.30.20.3-0.20.3
Total locomotion distance, hab. session 20.70.91.7-0.7-1.1-1.01.0-1.3-1.3-1.10.8-0.10.7-0.7
Locomotion velocity, hab. session 20.70.91.8-0.8-1.1-1.11.1-1.3-1.3-1.10.9-0.20.6-0.5
Novel to familiar place preference ratio0.30.31.3-0.3-0.8-0.60.6-1.2-0.7-0.60.20.4-0.10.0
Novelty place preference0.30.31.6-0.1-0.7-0.50.5-1.3-0.5-0.50.20.6-0.20.2
Time in novel zone, NPP test0.20.20.9-0.1-0.6-0.50.5-0.9-0.5-0.50.10.5-0.10.0
Total zone transitions, NPP test0.20.21.0-0.00.10.3-0.2-0.60.20.2-0.61.0-0.60.6
Total locomotion distance, NPP test0.20.30.5-0.3-0.6-0.60.6-0.5-0.7-0.70.20.40.5-0.4
Locomotion velocity, NPP test0.10.10.4-0.2-0.3-0.30.3-0.6-0.5-0.4-0.10.60.00.1
Intraocular pressure0.60.91.3-0.6-1.0-1.01.00.0-1.0-1.01.1-1.11.0-0.9
Delta distance traveled before/after self-admin0.10.10.8-0.0-0.2-0.20.20.9-0.2-0.3-0.10.30.4-0.4
Delta ambulatory time before/after self-admin0.40.51.2-0.0-0.6-0.60.61.0-0.6-0.70.30.11.1-1.0
Parametrial fat weight0.61.55.61.31.31.2-1.22.41.51.3-0.9-0.0-0.00.1
Pavlov. Cond. lever latency1.41.73.0-0.9-1.1-1.51.40.9-1.3-1.21.4-1.71.3-1.5
Pavlov. Cond. magazine entry latency1.21.62.5-1.6-1.4-1.41.4-1.4-1.3-1.50.8-0.51.3-0.9
Pavlov. Cond. change in total contacts0.10.10.40.0-0.10.3-0.2-0.60.00.0-0.50.60.4-0.3
Pavlov. Cond. index score0.20.31.9-0.3-0.3-0.10.1-1.4-0.2-0.3-0.30.70.10.2
Pavlov. Cond. latency score0.20.31.8-0.2-0.10.2-0.2-1.30.0-0.1-0.40.8-0.20.5
Pavlov. Cond. lever contacts1.41.63.51.01.11.4-1.4-0.41.31.2-1.71.9-1.01.2
Pavlov. Cond. magazine entry number1.01.23.71.41.21.0-1.11.91.11.2-0.70.3-0.70.5
Pavlov. Cond. intertrial magazine entries0.70.93.11.80.90.9-1.01.00.80.9-0.50.8-0.40.1
Pavlov. Cond. lever-magazine prob. diff.0.20.21.4-0.3-0.4-0.10.2-1.2-0.3-0.4-0.20.70.3-0.0
Pavlov. Cond. response bias0.30.42.2-0.8-0.6-0.40.4-1.5-0.5-0.60.00.20.3-0.1
Pavlov. Cond. lever latency1.11.42.4-1.3-1.5-1.41.4-0.5-1.3-1.30.7-0.11.3-1.3
Pavlov. Cond. magazine entry latency0.20.20.5-0.6-0.4-0.30.4-0.5-0.3-0.50.3-0.70.2-0.3
Pavlov. Cond. change in total contacts0.40.61.20.91.10.9-0.80.00.90.9-0.3-0.0-0.90.9
Pavlov. Cond. index score0.20.20.40.40.60.6-0.5-0.30.50.4-0.1-0.3-0.60.6
Pavlov. Cond. latency score0.10.10.20.30.40.3-0.3-0.30.30.20.1-0.3-0.40.3
Pavlov. Cond. lever contacts0.50.71.30.91.11.0-1.00.60.90.9-0.5-0.2-0.90.9
Pavlov. Cond. magazine entry number0.20.20.40.1-0.4-0.50.40.1-0.5-0.40.10.60.7-0.5
Pavlov. Cond. intertrial magazine entries0.81.24.91.60.80.8-0.90.50.80.9-1.02.2-0.70.8
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.40.50.5-0.4-0.30.40.40.1-0.4-0.50.4
Pavlov. Cond. response bias1.11.42.31.21.51.4-1.30.71.31.3-0.90.0-1.31.4
Time in closed arm before self-admin0.81.03.10.5-0.3-0.60.51.4-0.3-0.3-0.21.11.8-1.7
Time in closed arm after self-admin0.20.31.3-0.10.30.1-0.1-0.20.30.3-0.91.1-0.40.6
Time in open arm before self-admin0.40.41.3-0.60.30.4-0.5-0.70.30.3-0.2-0.7-1.11.1
Time in open arm after self-admin0.60.71.8-0.6-0.8-0.70.7-0.3-0.8-0.81.2-1.30.6-0.6
Bone: periosteal estimation0.81.64.62.11.51.4-1.31.11.11.1-0.91.4-0.60.7
Bone: periosteal perimeter1.42.45.12.31.81.6-1.51.31.51.4-1.52.1-0.90.9
Bone: post-yield work2.63.88.12.51.92.1-2.02.82.01.9-2.11.9-0.20.1
Progressive ratio test 1 active lever presses0.91.12.31.51.21.1-1.10.21.21.2-0.30.4-1.01.1
Progressive ratio test 1 breakpoint0.81.02.11.41.21.1-1.00.01.21.1-0.20.4-0.91.1
Progressive ratio test 1 inactive lever presses0.91.42.61.51.11.1-1.1-0.21.11.1-0.71.0-1.51.6
Progressive ratio test 2 active lever presses0.30.31.1-0.5-0.5-0.50.6-1.0-0.6-0.50.7-0.50.1-0.1
Progressive ratio test 2 breakpoint0.30.31.3-0.5-0.5-0.50.6-1.1-0.6-0.50.7-0.50.00.0
Progressive ratio test 2 inactive lever presses0.20.31.2-0.4-0.5-0.50.6-1.1-0.7-0.50.4-0.20.2-0.3
Incentive Sensitization - Responses0.60.91.7-1.3-1.0-1.01.0-1.3-1.1-1.00.5-0.20.5-0.6
Incentive Sensitization - Breakpoint0.70.81.6-1.3-1.0-1.01.0-1.1-1.1-1.00.5-0.30.6-0.7
Sum of active levers in priming session hrs 5-60.30.30.90.60.50.6-0.50.90.50.5-0.50.1-0.30.3
Progressive ratio0.61.03.5-1.0-0.8-0.90.9-1.9-0.9-0.81.2-1.00.3-0.3
Food seeking constrained by brief footshock1.41.73.4-0.9-1.4-1.31.4-0.1-1.4-1.41.0-0.71.8-1.8
Seeking ratio, punishment vs. effort0.20.21.1-0.0-0.2-0.20.21.1-0.2-0.2-0.30.30.8-0.8
Retroperitoneal fat weight0.10.64.1-0.70.2-0.0-0.22.00.30.2-0.7-1.10.5-0.4
Reaction time number correct1.42.75.41.11.71.9-1.92.31.71.8-2.20.8-1.10.9
Reaction time mean minus median0.10.20.5-0.5-0.3-0.30.4-0.7-0.4-0.40.10.40.2-0.2
Reaction time mean minus median AUC0.00.10.60.40.30.3-0.2-0.20.20.2-0.20.8-0.30.3
Reaction time num false alarms1.52.16.52.21.41.4-1.40.31.41.5-1.32.6-0.40.6
Reaction time num false alarms AUC0.71.14.51.50.90.9-0.90.20.91.0-1.02.1-0.10.1
Reaction time trials correct on left1.42.75.41.11.71.9-1.92.31.71.8-2.20.8-1.10.9
Reaction time trials on left1.52.75.31.21.71.9-1.92.31.71.8-2.20.8-1.10.9
Reaction time mean0.61.01.8-1.2-1.1-0.90.9-0.8-1.0-0.90.6-0.41.2-1.3
Reaction time mean AUC0.50.81.4-1.1-1.0-0.90.9-0.8-1.0-0.90.5-0.31.0-1.2
Median of all reaction times0.91.22.3-1.3-1.3-1.01.1-0.8-1.1-1.10.7-0.61.4-1.5
Reaction time omissions0.20.41.2-0.1-0.5-0.40.4-0.7-0.6-0.50.20.50.8-1.1
Reaction time false alarm rate0.40.53.31.20.40.3-0.3-0.70.40.4-0.21.80.10.0
Reaction time premature initiation rate0.20.31.30.30.20.3-0.3-0.80.30.30.4-0.1-1.01.1
Reaction time premature initiations0.61.01.90.91.01.1-1.20.41.01.1-0.60.4-1.31.4
Std. dev. reaction times0.61.02.2-1.5-1.1-1.01.1-1.3-1.1-1.10.7-0.40.7-0.8
Reaction time trials completed1.52.75.31.21.71.9-1.92.31.71.8-2.20.8-1.10.9
Reaction time trials AUC1.32.55.71.21.61.8-1.82.41.61.7-2.10.7-0.90.7
Run reversals in cocaine runway, females6.56.58.1-2.5-2.8-2.82.8-1.5-2.8-2.82.8-2.42.1-2.1
Run reversals in cocaine runway, males0.30.31.30.20.40.4-0.3-0.60.50.3-0.20.2-1.11.1
Latency to leave start box in cocaine runway0.30.32.1-1.5-0.2-0.40.3-0.0-0.3-0.2-0.2-0.8-0.10.1
Latency to leave start box in cocaine runway, F0.40.41.8-0.80.20.2-0.41.30.30.4-1.30.00.1-0.1
Latency to leave start box in cocaine runway, M0.70.61.7-1.2-0.4-0.60.6-1.3-0.5-0.41.0-1.2-0.50.5
Std. dev. time between licks in bursts0.10.10.40.2-0.6-0.20.2-0.2-0.4-0.30.40.3-0.10.1
Total sessions with >9 infusions0.30.40.70.60.70.7-0.60.20.70.7-0.20.0-0.80.8
Short access day 1 total inactive lever presses2.02.66.11.21.71.7-1.6-0.41.61.7-1.10.8-2.52.4
Short access day 10 total inactive lever presses0.20.51.80.80.50.7-0.6-0.20.40.5-1.01.3-0.60.5
Short access day 1 total infusions0.70.91.31.11.11.1-1.10.91.11.1-0.6-0.1-0.90.9
Short access day 10 total infusions0.50.72.20.50.70.6-0.6-0.60.70.70.3-0.3-1.41.5
Short access total infusions0.60.81.70.91.00.9-0.9-0.11.01.0-0.20.1-1.21.3
Short access day 1 locomotion1.31.63.11.01.31.3-1.30.31.31.3-1.30.8-1.81.7
Short access day 10 total locomotion0.10.20.50.70.30.2-0.3-0.60.20.30.20.3-0.50.5
Short access total locomotion0.40.50.90.90.70.7-0.7-0.30.70.7-0.40.5-1.00.9
One hour access (0.3 mA shock)0.30.41.00.3-0.3-0.40.40.0-0.4-0.31.0-0.61.0-1.0
Compulsive drug intake1.41.64.1-1.2-1.1-1.31.2-1.0-1.0-1.12.0-2.00.8-0.8
One hour access (shock baseline)0.00.00.10.3-0.10.10.00.3-0.2-0.1-0.10.20.2-0.2
Social response proportion2.02.35.1-1.3-1.2-1.11.21.4-1.2-1.01.3-2.31.9-2.1
Social responses0.70.93.51.00.70.7-0.71.90.90.9-0.70.80.4-0.7
Social time1.21.63.1-0.5-1.2-1.11.20.5-1.2-1.21.4-1.71.7-1.6
Soleus weight0.20.62.71.10.3-0.0-0.1-0.40.10.01.6-1.10.8-0.9
Bone: stiffness0.10.10.20.50.50.2-0.00.50.1-0.00.1-0.1-0.40.4
Tibialis anterior weight2.37.914.73.73.63.1-3.13.83.02.8-2.31.6-0.91.0
Time to tail flick, vehicle, before self-admin0.40.41.00.80.70.6-0.60.40.60.6-0.71.0-0.50.5
Time to tail flick, vehicle, after self-admin0.10.10.3-0.10.30.2-0.2-0.20.30.4-0.60.3-0.40.4
Time to tail flick, test, before self-admin0.20.20.5-0.1-0.2-0.40.4-0.4-0.4-0.30.4-0.00.7-0.7
Time to tail flick, test, after self-admin0.40.51.7-0.4-0.1-0.20.11.3-0.1-0.00.6-1.30.7-0.7
Delta time to tail flick, vehicle, before/after SA0.30.31.1-1.1-0.5-0.50.4-0.6-0.5-0.40.2-0.80.10.0
Delta time to tail flick, test, before/after SA1.11.13.7-1.3-1.0-0.90.90.5-0.9-0.91.1-1.90.9-0.9
Tibia length0.41.02.01.41.11.2-1.10.10.80.9-0.50.5-1.41.4
Ambulatory time before self-admin0.40.62.01.10.50.6-0.60.60.50.5-0.91.4-0.20.2
Ambulatory time after self-admin0.40.51.61.20.00.3-0.21.20.10.0-0.41.30.5-0.5
Bone: tissue strength0.50.52.60.40.50.5-0.51.60.50.6-0.2-0.50.5-0.7
Total heroin consumption0.30.30.50.20.70.7-0.7-0.20.70.7-0.50.1-0.70.7
Bone: trabecular number0.91.52.90.61.41.4-1.41.11.31.3-1.70.3-1.31.2
Bone: trabecular spacing1.72.32.9-1.6-1.5-1.61.7-1.0-1.7-1.61.7-1.31.4-1.4
Bone: trabecular thickness0.40.41.00.40.70.8-0.8-0.10.60.7-0.5-0.0-1.00.9
Bone: trabecular tissue density1.92.74.3-1.3-1.8-1.92.0-1.4-2.0-2.02.1-1.21.0-0.9
Water consumed over 24 hours0.30.41.1-0.5-0.4-0.30.40.7-0.4-0.40.5-1.00.9-1.0
Number of responses in last shaping day1.01.11.90.71.01.1-1.0-0.21.11.0-1.21.2-1.21.4