Hub : Genes

LOC120103502

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC120103502 0.07 0.03 2.5e-09 0.07 0.06 0.07 0.07 2.1e-10 5.3e-09 2.0e-11 4.8e-11
2 PL gene expression LOC120103502 0.28 0.1 9.2e-14 0.12 0.12 0.1 0.12 3.3e-13 1.5e-12 1.8e-11 3.1e-13
3 OFC mRNA stability LOC120103502 0.26 0.14 6.4e-05 0.18 0.18 0.13 0.18 4.2e-05 3.9e-05 5.3e-04 3.6e-05
4 PL mRNA stability LOC120103502 0.04 0.03 7.4e-05 0.03 0.03 0.03 0.03 1.7e-04 4.3e-04 2.1e-04 8.3e-04
5 IL gene expression LOC120103502 0.3 0.13 9.4e-06 0.21 0.2 0.18 0.2 7.7e-06 1.9e-05 4.9e-05 1.6e-05
6 IL mRNA stability LOC120103502 0.29 0.11 3.4e-07 0.22 0.26 0.24 0.23 4.5e-06 8.0e-07 2.3e-06 2.4e-06
7 Brain mRNA stability LOC120103502 0.06 0.03 1.1e-06 0.06 0.07 0.06 0.06 4.0e-06 4.2e-07 1.8e-06 2.0e-06
8 LHb mRNA stability LOC120103502 0.2 0.13 4.0e-04 0.1 0.15 0.15 0.11 3.0e-03 1.9e-04 2.1e-04 1.2e-03
9 BLA gene expression LOC120103502 0.11 0.06 9.9e-05 0.05 0.06 0.05 0.04 8.2e-04 7.2e-04 1.2e-03 3.2e-03
10 OFC gene expression LOC120103502 0.45 0.16 9.8e-06 0.21 0.26 0.23 0.23 8.1e-06 6.2e-07 4.4e-06 3.7e-06
11 IC mRNA stability LOC120103502 0.13 0.07 1.4e-03 0.01 0.04 0.06 0.01 1.6e-01 5.7e-03 2.0e-03 1.4e-01
12 Brain gene expression LOC120103502 0.48 0.1 4.1e-07 0.02 0.08 0.1 0.07 3.4e-03 3.1e-08 6.6e-10 3.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density2.54.211.5-1.7-1.9-2.0-1.7-1.8-2.9-1.8-2.8-1.4-0.5-3.4-0.6
Area under the delay curve0.40.50.8-0.7-0.7-0.7-0.3-0.8-0.9-0.9-0.6-0.6-0.80.1-0.5
BMI with tail2.69.112.63.53.03.03.53.02.93.52.73.13.11.13.0
BMI without tail2.37.010.73.22.72.62.92.82.33.01.92.43.30.52.9
Body weight1.87.710.83.23.13.03.33.02.52.62.42.53.02.22.1
Weight adjusted by age0.00.10.1-0.30.1-0.3-0.1-0.00.1-0.1-0.1-0.30.00.40.4
Bone surface0.30.64.1-0.3-0.5-0.4-0.3-0.4-1.1-0.3-1.1-0.20.3-2.00.2
Bone volume1.12.16.9-1.1-1.3-1.4-1.1-1.2-2.0-1.2-1.9-1.0-0.4-2.6-0.3
Breakpoint value in progressive ratio session2.12.58.1-1.2-1.8-1.9-1.6-1.6-1.9-1.1-1.4-0.5-1.0-2.80.4
Number of licking bursts1.82.94.12.01.82.01.91.81.81.71.71.61.51.40.8
Context. condit. distance diff. score0.20.20.7-0.3-0.1-0.3-0.1-0.1-0.50.0-0.8-0.40.7-0.80.3
Locomotion velocity, session 11.01.11.81.40.91.11.01.00.81.20.91.31.20.01.0
Locomotion distance, session 10.30.40.6-0.5-0.7-0.8-0.8-0.6-0.8-0.5-0.5-0.1-0.5-0.8-0.0
Locomotion velocity, session 20.60.71.40.70.90.90.90.90.90.80.70.60.61.20.2
Locomotion distance, session 20.10.10.40.1-0.2-0.2-0.4-0.2-0.3-0.00.10.5-0.4-0.60.0
Locomotion velocity, session 30.10.10.2-0.4-0.2-0.5-0.5-0.3-0.4-0.4-0.5-0.4-0.2-0.30.0
Locomotion distance, session 30.60.71.5-0.8-0.8-0.9-0.9-0.9-1.0-0.7-0.9-0.3-0.7-1.2-0.3
Stereotopy head waving bouts, day 31.41.63.0-1.2-1.3-1.3-1.0-1.3-1.5-1.3-1.7-1.7-0.5-1.0-0.7
Stereotopy head waving duration, day 30.10.10.4-0.1-0.1-0.00.0-0.0-0.1-0.2-0.3-0.60.10.6-0.4
Locomotion velocity, session 70.10.10.4-0.3-0.1-0.1-0.2-0.1-0.3-0.1-0.3-0.0-0.1-0.6-0.2
Locomotion distance, session 70.50.61.50.90.71.00.90.90.61.00.61.20.7-0.20.4
Stereotopy head waving bouts, day 70.00.10.10.30.30.20.20.10.10.10.20.20.30.30.4
Stereotopy head waving duration, day 70.00.00.3-0.10.0-0.1-0.1-0.1-0.1-0.3-0.0-0.3-0.00.50.1
Locomotion velocity, session 80.10.20.7-0.4-0.1-0.4-0.5-0.2-0.5-0.1-0.8-0.50.3-0.4-0.0
Locomotion distance, session 81.01.42.3-1.3-1.1-1.4-1.3-1.1-1.3-1.0-1.5-1.4-0.6-1.2-0.3
Degree of sensitization distance3.33.44.62.11.92.22.12.01.82.01.71.91.90.91.3
Degree of sensitization stereotypy0.60.71.31.00.90.80.60.60.80.71.11.10.40.50.9
Conditioned locomotion1.31.43.1-0.9-1.0-1.3-1.0-1.0-1.7-1.2-1.8-1.30.1-1.6-0.2
Cocaine response after cond. corrected0.50.61.80.80.30.30.30.40.40.90.81.40.2-1.21.2
Cocaine response after cond. not corrected0.10.20.90.1-0.3-0.2-0.3-0.2-0.10.10.30.6-0.5-0.90.3
Cocaine response before conditioning1.82.24.4-1.5-1.2-1.1-1.4-1.3-1.4-2.0-1.4-1.9-1.20.8-2.1
Saline control response1.31.73.2-1.3-1.2-1.2-1.3-1.2-1.8-1.8-1.6-1.4-0.9-0.4-1.2
Bone: connectivity density0.81.27.0-0.4-0.6-0.7-0.5-0.6-1.7-0.5-1.6-0.20.4-2.60.2
Bone: cortical apparent density0.10.10.80.50.10.1-0.10.0-0.5-0.2-0.10.30.1-0.90.2
Bone: cortical area0.20.30.80.30.30.30.20.30.70.80.90.9-0.10.10.6
Bone: cortical porosity0.30.41.2-0.5-0.4-0.4-0.3-0.5-0.4-0.8-0.5-1.1-0.30.8-0.6
Bone: cortical porosity0.40.51.3-0.7-0.6-0.6-0.5-0.7-0.7-0.8-0.9-1.1-0.20.2-0.6
Bone: cortical thickness0.40.61.90.60.50.60.30.61.00.81.41.4-0.20.50.5
Bone: cortical thickness0.50.61.6-0.8-0.9-0.8-1.0-0.8-0.8-0.5-0.40.2-0.9-1.3-0.3
Bone: cortical tissue density0.10.20.80.70.30.30.10.2-0.4-0.0-0.10.40.3-0.90.2
Condit. Reinf. active minus inactive responses3.64.05.62.22.12.22.02.02.42.22.42.21.31.11.4
Condit. Reinf. active-inactive response ratio1.61.72.41.41.41.41.31.21.61.51.51.40.80.70.9
Condit. Reinf. active responses1.21.52.11.41.21.31.21.31.31.41.41.41.00.40.9
Condit. Reinf. inactive responses0.20.21.0-0.2-0.4-0.4-0.3-0.2-0.6-0.2-0.6-0.20.3-1.00.1
Incentive salience index mean0.81.01.71.11.11.11.01.11.31.01.20.90.60.90.5
Condit. Reinf. lever presses0.81.11.9-1.2-1.0-1.0-1.1-0.9-0.8-1.4-0.8-1.3-1.10.1-1.3
Condit. Reinf. active minus inactive responses0.50.61.70.70.30.40.30.20.61.20.71.30.4-0.91.1
Condit. Reinf. active-inactive response ratio0.30.40.80.60.40.50.50.30.70.90.80.80.3-0.00.9
Condit. Reinf. active responses0.20.31.10.50.20.30.10.20.50.80.81.00.0-0.50.7
Condit. Reinf. inactive responses0.10.10.3-0.2-0.2-0.2-0.5-0.1-0.3-0.3-0.00.0-0.3-0.3-0.2
Condit. Reinf. lever presses0.10.10.5-0.1-0.3-0.1-0.4-0.3-0.0-0.30.2-0.0-0.70.1-0.4
Condit. Reinf. lever reinforcers received0.30.41.40.70.30.50.30.30.60.90.91.20.1-0.40.6
Conditioned reinforcement - actives1.62.85.8-1.8-2.0-2.1-1.7-1.8-1.7-1.3-1.3-1.1-1.6-2.4-0.4
Conditioned reinforcement - inactives1.92.84.1-2.0-1.9-1.6-1.7-1.7-1.3-1.4-1.3-1.4-2.0-1.5-2.0
Conditioned locomotion2.12.75.3-1.6-1.9-1.4-1.3-1.7-1.5-1.6-1.4-1.6-1.9-1.1-2.3
Patch foraging indifference point 0 sec0.20.40.6-0.6-0.7-0.7-0.8-0.6-0.8-0.6-0.8-0.4-0.6-0.8-0.3
Patch foraging indifference point AUC0.20.30.80.30.40.40.70.40.80.90.40.50.70.20.4
Delay disc. indifference point, 0s delay0.30.30.80.50.30.40.80.40.60.50.90.7-0.00.80.5
Delay disc. indifference point, 16s delay0.80.91.4-1.1-0.9-1.0-0.7-1.0-1.1-1.2-0.9-0.9-1.0-0.0-0.7
Delay disc. indifference point, 2s delay0.20.20.9-0.2-0.4-0.20.2-0.4-0.1-0.40.0-0.4-0.61.0-0.5
Delay disc. indifference point, 24s delay3.53.911.0-1.8-2.1-2.4-2.1-2.2-2.3-1.4-1.9-0.9-1.5-3.3-0.1
Delay disc. indifference point, 4s delay0.70.72.0-0.7-0.4-0.4-0.0-0.5-0.6-1.2-0.7-1.2-0.71.4-1.1
Delay disc. indifference point, 8s delay0.60.71.5-0.8-0.8-1.0-0.5-0.9-1.2-1.0-1.0-0.7-0.6-0.5-0.1
Indifference point function ln k1.22.13.0-1.3-1.7-1.4-1.7-1.6-1.7-1.4-1.2-0.8-1.5-1.6-0.9
Indifference point function log k1.22.13.0-1.3-1.7-1.4-1.7-1.6-1.7-1.4-1.2-0.8-1.5-1.6-0.9
Patch foraging total patch changes 0 sec0.20.40.6-0.6-0.7-0.7-0.7-0.7-0.7-0.5-0.7-0.3-0.6-0.8-0.3
Patch foraging total patch changes 12 sec0.20.21.20.20.50.50.50.50.60.30.40.20.31.1-0.0
Patch foraging total patch changes 18 sec0.10.20.40.40.30.20.30.20.20.7-0.10.50.6-0.60.6
Patch foraging total patch changes 24 sec0.10.10.30.30.30.20.30.30.50.40.50.50.0-0.10.3
Patch foraging total patch changes 6 sec0.10.10.40.00.30.10.30.30.60.50.40.4-0.10.50.3
Patch foraging time to switch 0 sec0.10.10.30.40.60.30.40.40.10.0-0.1-0.30.50.10.2
Patch foraging water rate 0 sec1.73.54.9-2.0-2.2-2.0-2.0-2.1-2.0-1.8-1.7-1.3-1.9-1.8-1.3
Patch foraging water rate 12 sec0.10.10.4-0.0-0.10.1-0.2-0.10.1-0.10.50.4-0.60.6-0.4
Patch foraging water rate 18 sec2.13.26.0-2.1-2.1-1.8-2.1-1.9-1.6-2.0-1.1-1.2-2.4-0.3-1.8
Patch foraging water rate 24 sec0.00.10.1-0.3-0.3-0.2-0.0-0.3-0.3-0.2-0.20.0-0.3-0.3-0.3
Patch foraging water rate 6 sec0.71.02.6-1.1-1.1-1.0-1.2-1.2-0.7-0.9-0.3-0.3-1.6-0.8-0.7
Seeking ratio, delayed vs. immediate footshock1.41.73.81.01.21.21.41.12.01.71.71.30.50.61.2
Distance traveled before self-admin0.10.10.20.30.10.3-0.10.30.10.30.20.30.4-0.50.5
Distance traveled after self-admin0.40.52.80.30.30.10.20.60.30.50.40.70.3-1.01.7
Extensor digitorum longus weight1.24.76.4-2.2-2.4-2.5-2.3-2.2-2.5-2.2-2.3-2.0-1.9-2.0-1.3
Bone: elastic displacement0.91.02.6-0.9-1.0-1.1-1.2-1.1-1.1-0.8-1.0-0.6-0.9-1.6-0.2
Bone: elastic work1.52.02.8-1.6-1.5-1.5-1.7-1.6-1.4-1.3-1.3-1.3-1.5-1.5-0.8
Bone: endosteal estimation0.20.31.2-0.6-0.6-0.6-0.3-0.5-0.4-0.2-0.8-0.8-0.0-1.10.2
Bone: endosteal perimeter0.00.00.1-0.1-0.2-0.10.2-0.1-0.00.1-0.3-0.30.3-0.00.1
Epididymis fat weight13.044.455.77.57.37.47.27.26.56.56.46.56.85.54.4
Delta time in closed arm before/after self-admin0.30.31.0-0.4-0.6-0.4-0.7-0.6-0.6-0.1-0.40.2-0.4-1.0-0.2
Delta time in open arm before/after self-admin1.31.32.41.31.21.11.41.10.91.10.91.11.60.81.1
Diff in mean of infusions in LGA sessions0.10.10.3-0.0-0.1-0.1-0.00.3-0.6-0.6-0.4-0.20.30.00.3
Delay discount exponential model param0.91.01.51.01.11.10.61.21.21.21.00.91.00.20.8
Extinction: sum of active levers before priming1.61.73.3-1.2-1.4-1.8-1.4-1.5-1.6-1.4-1.4-1.1-1.0-1.10.1
Active lever presses in extinction session 61.21.13.6-1.1-1.1-1.4-1.1-0.9-0.9-0.6-0.7-0.2-1.0-1.91.0
Bone: final force0.20.40.80.50.70.60.60.80.70.50.70.40.40.90.4
Bone: final moment0.20.20.40.40.50.40.40.60.60.50.60.40.20.60.5
Food consumed during 24 hour testing period0.50.71.60.90.81.00.70.80.80.90.91.30.60.70.4
Glucose1.32.03.81.81.51.51.51.50.71.50.91.81.9-0.21.2
Heart weight1.52.32.91.71.51.71.71.61.71.61.51.31.41.30.9
Delay discount hyperbolic model param0.40.50.80.70.70.70.20.80.90.90.70.70.7-0.10.6
Intermittent access intake day 1-15 change0.51.12.5-0.9-1.1-1.2-0.6-1.0-1.6-1.1-1.3-1.0-0.3-1.3-0.1
Intermittent access intake escalation0.40.81.9-0.8-0.9-1.0-0.4-0.8-1.4-1.0-1.2-0.9-0.2-1.0-0.0
Intermittent access intake escalation 20.40.51.8-0.4-0.7-0.8-0.1-0.4-0.9-0.4-0.8-0.40.2-1.30.8
Intermitt. access day 1 inactive lever presses0.10.20.8-0.00.00.50.40.30.50.20.30.0-0.10.9-0.8
Intermitt. access day 15 inactive lever presses0.10.31.0-0.20.20.50.70.40.70.40.2-0.10.10.8-1.0
Intermitt. access escalation Index1.31.82.81.41.71.41.51.51.61.51.31.11.30.80.9
Intermittent access day 1 total infusions1.42.24.7-1.6-1.5-1.3-1.3-1.4-1.0-1.6-1.1-1.8-1.80.2-2.2
Intermittent access day 15 total infusions1.62.33.8-1.6-1.6-1.5-1.2-1.5-1.6-1.9-1.5-2.0-1.3-0.4-1.5
Intermittent access terminal intake (last 3 days)2.02.64.0-1.9-1.8-1.7-1.4-1.6-1.5-2.0-1.2-1.9-1.9-0.2-1.7
Intermittent access total infusions3.84.57.9-2.3-2.3-1.9-2.0-2.1-1.9-2.4-1.7-2.4-2.4-0.2-2.8
Intermittent access day 1 locomotion1.82.38.8-1.4-1.4-0.9-1.6-1.5-0.6-1.3-0.5-1.4-2.30.0-3.0
Intermittent access day 15 total locomotion0.20.42.7-0.3-0.20.1-0.0-0.20.0-0.40.2-0.3-0.81.2-1.6
Intermittent access total locomotion2.53.010.2-1.7-1.7-1.1-1.4-1.6-1.2-1.9-1.0-1.7-2.30.7-3.2
Intermittent access standard deviation0.61.22.0-1.2-1.1-1.0-0.8-0.9-1.4-1.4-1.3-1.3-0.7-0.2-1.0
Left kidney weight0.21.02.21.21.21.01.21.20.60.80.60.81.50.60.9
Right kidney weight0.73.03.71.91.91.91.91.91.61.81.51.81.91.41.3
Cocaine induced anxiety0.71.02.5-0.6-0.9-0.8-0.6-0.8-1.5-1.0-1.6-1.10.1-1.4-0.3
Post-drug Anxiety1.11.23.31.41.21.11.31.10.60.90.50.71.80.31.2
Baseline Anxiety4.65.38.02.22.52.42.22.42.82.42.72.21.92.11.6
Tail length0.10.61.3-0.5-0.5-0.7-1.0-0.5-1.1-1.1-0.9-0.9-0.4-0.0-0.5
Length with tail0.10.32.10.10.40.30.00.3-0.2-0.60.0-0.30.11.5-0.6
Length without tail0.10.32.1-0.3-0.0-0.1-0.0-0.2-0.2-0.60.0-0.4-0.41.4-0.6
Times rat made contact with spout1.82.13.3-1.6-1.4-1.5-1.5-1.4-1.7-1.6-1.8-1.6-1.0-0.6-1.2
Lifetime Intake3.94.79.9-2.3-2.3-1.9-2.1-2.1-1.7-2.4-1.6-2.4-2.60.0-3.2
Liver weight, left0.81.35.50.91.01.10.60.91.40.51.70.8-0.32.3-0.1
Liver weight, right2.74.87.92.62.22.22.22.12.12.62.32.81.80.51.8
Locomotor activity1.62.55.51.51.91.91.91.81.51.11.30.91.52.30.5
Locomotor testing distance1.01.73.41.41.61.71.61.51.00.80.80.71.51.90.3
Locomotor testing rearing0.10.30.70.50.60.80.60.60.50.40.40.50.20.5-0.3
Locomotion in novel chamber0.50.64.0-0.00.00.30.20.00.5-0.20.5-0.2-0.72.0-1.3
Locomotion in novel chamber post-restriction0.81.32.11.41.01.41.01.11.01.01.31.51.01.10.5
Fecal boli incidents, locomotor time 12.73.95.1-2.0-2.1-2.0-1.9-2.3-2.1-1.9-2.0-1.7-2.0-1.7-2.0
Change in fecal boli incidents, locomotor task0.60.63.90.50.80.70.60.90.70.10.5-0.10.62.00.2
Time >=10cm from walls, locomotor time 10.60.72.70.90.60.40.00.3-0.80.2-0.40.71.4-1.70.7
Bouts of movement, locomotor time 13.03.47.9-2.0-1.8-1.4-2.1-1.7-1.1-1.9-1.4-2.3-2.20.1-2.8
Total resting periods, locomotor time 12.52.87.3-1.8-1.6-1.1-1.9-1.4-1.0-1.7-1.4-2.1-1.8-0.1-2.7
Rest time, locomotor task time 11.11.34.9-1.2-0.9-0.5-1.2-0.8-0.6-1.1-1.0-1.5-1.20.1-2.2
Distance moved, locomotor task time 11.52.34.51.71.41.21.51.41.11.51.41.81.61.02.1
Vertical activity count, locomotor time 10.20.42.10.80.50.20.10.30.30.60.71.00.5-0.21.4
Time >=10cm from walls, locomotor time 20.60.95.3-0.1-0.5-0.4-1.1-0.8-1.2-0.1-0.90.30.1-2.3-0.8
Bouts of movement, locomotor time 20.30.51.9-1.0-0.9-0.5-0.4-0.6-0.2-0.5-0.3-0.7-1.10.2-1.4
Total resting periods, locomotor time 20.40.62.5-1.0-0.9-0.5-0.5-0.7-0.2-0.5-0.3-0.6-1.10.1-1.6
Rest time, locomotor task time 20.20.31.5-0.4-0.4-0.0-0.5-0.2-0.2-0.3-0.4-0.4-0.4-0.4-1.2
Distance moved, locomotor task time 20.30.31.60.50.40.30.50.40.50.20.70.30.11.30.8
Vertical activity count, locomotor time 20.10.10.2-0.1-0.4-0.4-0.5-0.4-0.4-0.2-0.00.3-0.5-0.50.1
Light reinforcement 10.20.41.2-0.7-0.2-0.4-0.3-0.4-0.3-0.8-0.4-0.9-0.70.5-1.1
Light reinforcement 20.30.51.3-0.5-0.5-0.6-0.5-0.5-1.2-1.0-1.0-1.00.0-0.3-0.5
Bone: marrow area0.20.41.1-0.7-0.6-0.6-0.3-0.5-0.4-0.3-0.8-0.8-0.1-1.00.1
Bone: maximum diameter0.00.10.2-0.3-0.3-0.3-0.1-0.20.10.2-0.0-0.00.1-0.30.5
Bone: maximum force0.10.10.6-0.4-0.0-0.1-0.00.10.2-0.10.2-0.2-0.40.8-0.1
Bone: maximum moment0.10.10.3-0.5-0.2-0.3-0.2-0.10.1-0.20.0-0.2-0.60.4-0.0
Mean time between licks in bursts0.41.11.61.31.11.21.21.11.11.10.90.91.20.60.5
Mean num. licks in bursts3.85.97.8-2.8-2.5-2.8-2.6-2.6-2.7-2.5-2.7-2.4-2.0-1.8-1.4
Cd content in liver2.02.33.61.81.41.41.21.41.01.81.01.91.9-0.91.8
Co content in liver1.01.21.5-1.1-1.2-1.1-1.2-1.1-1.1-1.2-1.0-1.1-1.1-0.9-0.8
Cu content in liver0.40.51.20.90.90.80.90.90.30.4-0.00.21.10.30.3
Fe content in liver1.31.63.3-1.4-1.2-1.2-1.0-1.2-1.5-1.4-1.8-1.5-0.7-0.7-1.3
K content in liver1.51.53.21.11.51.31.21.41.40.91.00.41.21.80.4
Mg content in liver0.10.10.30.30.50.40.30.40.20.1-0.0-0.20.50.5-0.1
Mn content in liver0.00.00.10.20.10.30.20.20.1-0.00.10.0-0.2-0.1-0.3
Na content in liver1.01.01.5-1.1-1.1-1.0-1.0-1.1-0.9-1.2-0.9-1.2-1.10.1-1.0
Rb content in liver0.20.20.70.10.70.50.50.60.40.3-0.2-0.20.80.7-0.2
Se content in liver0.20.31.90.10.10.30.20.10.0-0.50.1-0.5-0.21.4-0.8
Sr content in liver3.63.14.4-1.7-2.1-1.7-1.6-1.9-2.1-2.0-2.0-1.7-1.5-1.1-1.5
Zn content in liver2.73.03.91.92.01.91.91.91.71.61.61.31.91.61.3
Bone: minimum diameter1.01.92.71.41.41.51.41.41.61.51.51.41.01.11.0
Time in familiar zone, hab. session 10.50.51.50.70.60.70.60.60.70.50.80.60.31.20.3
Time in novel zone, hab. session 10.50.51.20.70.90.80.90.90.50.70.30.51.1-0.20.5
Total zone transitions, hab. session 10.20.30.6-0.5-0.6-0.6-0.8-0.6-0.8-0.6-0.5-0.2-0.4-0.3-0.2
Total locomotion distance, hab. session 10.71.01.4-0.8-1.2-0.9-1.2-1.1-1.2-1.1-0.9-0.6-1.1-0.5-1.0
Locomotion velocity, hab. session 11.21.72.5-1.2-1.6-1.3-1.6-1.4-1.4-1.5-1.0-1.0-1.5-0.5-1.3
Time in familiar zone, hab. session 20.30.30.7-0.8-0.5-0.6-0.6-0.6-0.3-0.4-0.4-0.6-0.8-0.2-0.5
Time in novel zone, hab. session 21.81.93.61.91.31.51.51.40.71.40.81.51.9-0.21.3
Total zone transitions, hab. session 20.60.71.2-0.9-0.9-1.0-1.1-0.9-1.1-0.9-1.1-0.7-0.5-0.6-0.4
Total locomotion distance, hab. session 20.60.81.5-0.9-0.9-0.9-0.9-0.8-1.1-1.0-1.2-1.1-0.5-0.3-0.7
Locomotion velocity, hab. session 20.81.11.7-1.1-1.1-1.0-1.0-0.9-1.2-1.2-1.3-1.3-0.6-0.1-0.9
Novel to familiar place preference ratio0.20.30.70.40.40.50.60.40.60.80.50.80.2-0.10.0
Novelty place preference0.60.61.20.70.80.90.90.81.01.10.91.10.30.30.2
Time in novel zone, NPP test0.60.61.10.70.80.80.80.70.91.10.81.00.50.10.3
Total zone transitions, NPP test0.40.61.2-0.6-0.6-0.9-0.9-0.7-1.0-0.8-1.1-0.90.0-0.70.0
Total locomotion distance, NPP test1.11.53.0-1.1-1.2-1.3-1.3-1.1-1.7-1.4-1.7-1.4-0.4-0.9-0.7
Locomotion velocity, NPP test1.52.03.3-1.4-1.4-1.5-1.5-1.3-1.8-1.7-1.8-1.6-0.8-0.7-1.0
Intraocular pressure2.13.04.72.21.61.71.61.61.52.01.62.01.8-0.22.1
Delta distance traveled before/after self-admin0.90.91.70.81.10.71.21.10.90.80.91.00.70.51.3
Delta ambulatory time before/after self-admin0.10.10.6-0.10.0-0.20.30.20.10.10.10.2-0.1-0.50.8
Parametrial fat weight20.347.861.27.87.67.77.47.57.16.67.16.66.36.04.7
Pavlov. Cond. lever latency0.30.40.90.50.50.50.60.40.70.90.80.90.20.40.6
Pavlov. Cond. magazine entry latency0.40.52.7-0.3-0.6-0.6-0.6-0.5-0.8-0.4-0.7-0.2-0.0-1.60.2
Pavlov. Cond. change in total contacts0.80.82.8-0.6-1.0-0.9-0.9-1.0-1.0-0.8-0.8-0.6-0.9-1.7-0.3
Pavlov. Cond. index score0.50.71.1-0.7-0.8-0.8-0.8-0.7-1.1-1.0-1.0-0.9-0.4-1.0-0.5
Pavlov. Cond. latency score0.50.61.1-0.6-0.7-0.7-0.6-0.6-1.0-0.9-1.0-0.9-0.2-1.0-0.4
Pavlov. Cond. lever contacts0.50.61.1-0.7-0.7-0.8-0.8-0.7-0.8-1.0-0.8-1.0-0.6-0.4-0.7
Pavlov. Cond. magazine entry number0.70.93.60.70.91.00.90.91.10.71.10.70.41.90.1
Pavlov. Cond. intertrial magazine entries1.31.62.5-1.3-1.1-1.4-1.2-1.3-1.6-1.5-1.5-1.4-0.7-0.6-0.8
Pavlov. Cond. lever-magazine prob. diff.0.91.11.7-0.9-1.0-1.1-1.0-1.0-1.3-1.2-1.2-1.1-0.6-1.3-0.5
Pavlov. Cond. response bias1.41.72.5-1.2-1.3-1.5-1.4-1.3-1.5-1.3-1.5-1.3-0.8-1.6-0.6
Pavlov. Cond. lever latency0.10.20.50.40.20.20.40.30.30.50.50.60.2-0.50.7
Pavlov. Cond. magazine entry latency0.91.11.81.11.21.11.01.11.01.30.71.01.30.20.9
Pavlov. Cond. change in total contacts0.40.71.10.81.01.00.90.90.70.80.60.71.10.80.3
Pavlov. Cond. index score0.10.10.40.30.50.40.30.40.40.30.10.10.50.60.0
Pavlov. Cond. latency score0.10.10.30.30.40.40.30.30.30.30.00.10.50.50.1
Pavlov. Cond. lever contacts0.10.10.6-0.10.10.2-0.00.00.0-0.2-0.2-0.30.10.8-0.5
Pavlov. Cond. magazine entry number1.11.42.5-1.3-1.3-1.3-1.2-1.3-1.1-1.3-0.7-1.1-1.6-0.5-1.0
Pavlov. Cond. intertrial magazine entries0.00.10.20.3-0.00.10.0-0.00.10.00.40.3-0.3-0.40.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.40.60.60.50.50.40.40.20.20.70.60.2
Pavlov. Cond. response bias0.00.00.10.00.20.10.00.1-0.00.0-0.2-0.10.40.3-0.1
Time in closed arm before self-admin0.50.62.80.20.60.80.71.00.40.0-0.0-0.70.91.7-0.7
Time in closed arm after self-admin1.21.33.80.81.01.41.21.41.30.81.20.70.72.0-0.1
Time in open arm before self-admin0.30.41.2-0.0-0.4-0.6-1.1-0.8-0.4-0.4-0.10.0-0.7-1.00.3
Time in open arm after self-admin0.20.21.1-0.1-0.2-0.5-0.8-0.6-0.5-0.2-0.4-0.2-0.1-1.1-0.1
Bone: periosteal estimation0.10.10.5-0.4-0.4-0.4-0.2-0.3-0.00.1-0.2-0.2-0.2-0.70.4
Bone: periosteal perimeter0.10.10.3-0.5-0.4-0.3-0.3-0.4-0.1-0.3-0.2-0.4-0.30.4-0.3
Bone: post-yield work1.62.43.8-2.0-1.7-1.8-1.6-1.5-1.6-1.5-1.8-1.5-1.3-1.0-1.0
Progressive ratio test 1 active lever presses1.62.07.4-1.4-1.1-0.8-1.0-1.0-0.6-1.5-0.7-1.6-1.81.2-2.7
Progressive ratio test 1 breakpoint1.62.07.1-1.4-1.1-0.8-1.0-1.1-0.7-1.5-0.8-1.7-1.71.0-2.7
Progressive ratio test 1 inactive lever presses1.92.714.9-1.4-0.7-0.4-0.5-0.7-0.1-1.3-0.7-1.7-1.82.3-3.9
Progressive ratio test 2 active lever presses2.73.14.7-1.9-2.0-2.0-1.9-1.9-1.6-1.8-1.3-1.6-2.2-1.0-1.5
Progressive ratio test 2 breakpoint2.63.04.8-1.9-2.0-2.0-1.9-1.9-1.5-1.8-1.2-1.5-2.2-1.0-1.5
Progressive ratio test 2 inactive lever presses1.11.84.6-1.7-1.5-1.3-1.2-1.3-0.7-1.0-0.9-1.2-1.8-0.5-2.1
Incentive Sensitization - Responses1.31.85.8-1.0-1.5-1.8-1.6-1.5-1.2-0.7-0.7-0.4-1.3-2.40.4
Incentive Sensitization - Breakpoint1.21.55.0-0.9-1.5-1.7-1.5-1.4-1.1-0.6-0.5-0.3-1.3-2.20.5
Sum of active levers in priming session hrs 5-60.70.72.8-0.5-0.8-1.1-0.7-0.9-0.9-0.3-0.7-0.1-0.5-1.70.3
Progressive ratio0.71.11.91.11.21.01.01.11.21.40.81.01.30.70.5
Food seeking constrained by brief footshock4.55.58.7-2.2-2.4-2.5-2.7-2.4-2.9-2.4-2.7-2.0-1.6-2.6-1.4
Seeking ratio, punishment vs. effort1.72.43.7-1.6-1.7-1.7-1.6-1.7-1.9-1.8-1.6-1.3-1.3-1.6-0.5
Retroperitoneal fat weight26.3112.1142.511.911.711.911.511.510.810.010.59.79.99.76.7
Reaction time number correct0.20.41.10.70.50.50.30.5-0.20.4-0.00.71.0-1.00.7
Reaction time mean minus median0.51.42.71.61.11.11.11.10.51.20.81.41.6-0.51.4
Reaction time mean minus median AUC0.71.82.81.71.41.31.31.30.91.41.11.61.6-0.11.5
Reaction time num false alarms0.81.11.90.91.21.11.41.21.00.90.70.61.31.20.6
Reaction time num false alarms AUC0.61.01.61.01.11.11.21.10.90.80.70.61.31.10.7
Reaction time trials correct on left0.20.41.10.70.50.50.30.5-0.20.4-0.00.71.0-1.00.7
Reaction time trials on left0.20.41.20.80.50.50.40.5-0.10.50.10.81.1-1.00.7
Reaction time mean0.10.20.80.60.10.30.30.1-0.20.40.10.60.4-0.90.4
Reaction time mean AUC0.10.21.10.60.10.20.20.1-0.10.50.20.70.3-1.10.5
Median of all reaction times0.10.21.40.1-0.4-0.2-0.2-0.4-0.6-0.0-0.30.2-0.1-1.2-0.0
Reaction time omissions0.50.71.11.00.80.80.70.80.61.00.71.01.0-0.31.0
Reaction time false alarm rate0.40.62.30.50.70.70.90.70.90.50.70.20.51.50.3
Reaction time premature initiation rate0.50.71.5-0.7-0.4-0.4-0.6-0.4-0.9-1.2-1.0-1.1-0.21.0-1.2
Reaction time premature initiations0.20.30.8-0.3-0.1-0.1-0.4-0.1-0.9-0.8-0.9-0.60.30.1-0.7
Std. dev. reaction times0.61.02.01.40.80.80.70.80.21.10.61.41.3-1.11.3
Reaction time trials completed0.20.41.20.80.50.50.40.5-0.10.50.10.81.1-1.00.7
Reaction time trials AUC0.20.51.20.90.50.60.40.6-0.10.50.10.81.1-0.90.8
Run reversals in cocaine runway, females0.70.71.4-1.2-0.9-1.0-1.0-0.8-0.8-0.7-0.9-0.7-0.8-0.7-0.4
Run reversals in cocaine runway, males0.10.10.6-0.4-0.3-0.3-0.5-0.20.1-0.10.30.1-0.8-0.20.3
Latency to leave start box in cocaine runway1.31.45.1-0.9-0.9-1.1-1.2-0.9-1.5-0.6-1.8-0.90.3-2.20.2
Latency to leave start box in cocaine runway, F0.50.62.2-0.8-0.7-0.9-1.0-0.7-0.7-0.1-0.9-0.40.0-1.50.5
Latency to leave start box in cocaine runway, M1.00.93.5-0.3-0.6-0.6-0.5-0.5-1.5-0.7-1.6-0.70.5-1.9-0.0
Std. dev. time between licks in bursts0.10.10.20.20.30.40.40.30.20.30.10.30.30.1-0.4
Total sessions with >9 infusions4.15.015.8-2.2-2.1-1.7-2.3-2.1-1.5-2.2-1.4-2.3-2.80.2-4.0
Short access day 1 total inactive lever presses2.53.311.2-2.0-1.9-1.3-1.4-1.7-1.1-1.6-1.4-1.8-2.30.2-3.3
Short access day 10 total inactive lever presses0.10.20.5-0.1-0.3-0.10.1-0.2-0.40.2-0.70.10.4-0.7-0.7
Short access day 1 total infusions1.92.610.7-1.6-1.4-1.0-1.3-1.3-0.9-1.5-1.1-2.0-1.70.5-3.3
Short access day 10 total infusions3.14.07.2-2.1-2.2-1.9-2.1-2.1-1.7-2.2-1.6-2.1-2.3-0.4-2.7
Short access total infusions2.53.210.4-1.8-1.7-1.3-1.5-1.6-1.1-1.8-1.1-2.0-2.20.6-3.2
Short access day 1 locomotion1.82.28.2-1.4-1.3-1.0-1.3-1.3-0.7-1.4-0.8-1.7-1.80.6-2.9
Short access day 10 total locomotion0.81.44.8-0.9-1.2-0.6-0.9-1.1-1.2-1.4-1.1-1.2-1.2-0.4-2.2
Short access total locomotion3.03.614.6-1.6-1.8-1.1-1.7-1.7-1.3-1.8-1.1-1.7-2.40.1-3.8
One hour access (0.3 mA shock)4.14.76.3-2.4-2.5-2.4-2.1-2.2-2.3-2.1-2.2-2.3-1.8-1.8-1.6
Compulsive drug intake0.30.40.90.70.50.60.60.40.51.00.40.80.6-0.40.6
One hour access (shock baseline)3.35.16.4-2.5-2.5-2.5-2.3-2.3-2.2-2.5-2.0-2.4-2.3-1.1-2.0
Social response proportion0.20.20.7-0.4-0.3-0.1-0.1-0.20.0-0.4-0.1-0.7-0.60.7-0.8
Social responses0.30.40.90.50.60.70.70.80.90.90.70.50.60.20.4
Social time0.91.22.9-1.0-0.8-0.7-1.0-0.8-0.9-1.6-0.7-1.4-1.20.5-1.7
Soleus weight3.710.914.3-3.6-3.3-3.8-3.7-3.4-3.7-3.5-3.6-3.3-2.8-2.6-1.9
Bone: stiffness0.71.11.90.81.01.01.11.11.31.01.21.00.61.40.8
Tibialis anterior weight1.34.46.2-2.2-2.2-2.5-2.4-2.2-2.3-2.2-2.1-2.1-1.9-1.8-1.1
Time to tail flick, vehicle, before self-admin0.10.10.40.3-0.3-0.0-0.2-0.3-0.0-0.30.2-0.1-0.60.6-0.6
Time to tail flick, vehicle, after self-admin1.62.14.21.61.51.72.11.51.31.11.10.91.51.80.6
Time to tail flick, test, before self-admin2.02.03.0-1.7-1.3-1.6-1.3-1.4-1.4-1.7-1.1-1.6-1.6-0.1-1.5
Time to tail flick, test, after self-admin2.72.83.7-1.5-1.8-1.5-1.7-1.8-1.9-1.9-1.7-1.8-1.5-0.9-1.7
Delta time to tail flick, vehicle, before/after SA0.50.51.40.50.80.71.10.70.40.60.20.41.20.40.5
Delta time to tail flick, test, before/after SA1.71.72.7-1.1-1.5-0.9-1.4-1.3-1.4-1.3-1.6-1.4-1.0-1.1-1.6
Tibia length1.95.26.72.22.52.42.12.42.62.32.62.21.72.61.4
Ambulatory time before self-admin0.10.10.40.30.30.3-0.00.40.10.30.30.30.6-0.40.7
Ambulatory time after self-admin0.81.05.50.70.60.40.60.80.70.90.81.10.6-0.72.3
Bone: tissue strength0.30.31.0-0.6-0.2-0.3-0.4-0.30.0-0.70.0-0.8-1.00.8-0.5
Total heroin consumption5.05.912.2-2.3-2.9-2.7-2.8-2.7-2.4-1.8-2.0-1.4-2.3-3.5-1.4
Bone: trabecular number2.43.97.1-1.9-1.9-2.1-1.7-1.9-2.7-1.9-2.6-1.8-0.9-2.4-0.9
Bone: trabecular spacing1.21.64.21.11.01.20.90.92.01.42.01.5-0.21.10.5
Bone: trabecular thickness1.01.33.5-0.7-0.9-1.0-0.8-0.8-1.9-1.4-1.8-1.20.2-1.4-0.4
Bone: trabecular tissue density0.10.20.60.40.40.30.20.3-0.2-0.2-0.3-0.30.80.70.3
Water consumed over 24 hours0.10.20.40.40.40.40.30.40.30.60.00.50.6-0.40.4
Number of responses in last shaping day1.01.14.3-1.0-1.1-0.6-0.8-0.9-0.8-0.8-1.0-0.9-0.9-0.5-2.1