Hub : Genes

LOC120103502

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability LOC120103502 0.05 0.03 3.0e-05 0.04 0.03 0.03 0.04 1.6e-05 1.8e-04 1.6e-04 6.5e-05
2 PL gene expression LOC120103502 0.26 0.1 4.8e-14 0.14 0.12 0.13 0.14 1.8e-15 4.1e-13 4.0e-14 1.1e-14
3 IL mRNA stability LOC120103502 0.28 0.12 7.8e-07 0.26 0.26 0.24 0.26 4.8e-07 7.1e-07 1.5e-06 6.2e-07
4 OFC gene expression LOC120103502 0.36 0.15 7.3e-05 0.21 0.16 0.18 0.22 1.0e-05 1.3e-04 4.1e-05 5.9e-06
5 NAcc gene expression LOC120103502 0.03 0.02 6.2e-04 0.04 0.02 0.02 0.03 2.5e-05 1.0e-03 5.1e-03 3.4e-04
6 IL gene expression LOC120103502 0.3 0.13 1.6e-05 0.2 0.17 0.12 0.19 1.2e-05 5.5e-05 6.6e-04 3.1e-05
7 OFC mRNA stability LOC120103502 0.25 0.13 8.8e-05 0.15 0.16 0.08 0.17 2.3e-04 1.0e-04 6.4e-03 8.6e-05
8 LHb mRNA stability LOC120103502 0.19 0.13 1.1e-03 0.1 0.12 0.1 0.1 2.1e-03 1.1e-03 2.5e-03 1.9e-03
9 BLA gene expression LOC120103502 0.09 0.05 1.1e-04 0.08 0.06 0.05 0.05 4.5e-05 5.3e-04 8.0e-04 7.9e-04
10 Brain mRNA stability LOC120103502 0.07 0.03 1.7e-07 0.06 0.07 0.06 0.06 5.4e-06 6.4e-07 1.4e-06 3.1e-06
11 Brain gene expression LOC120103502 0.55 0.09 1.8e-07 0.03 0.09 0.1 0.08 6.2e-04 1.2e-08 4.0e-09 3.9e-08
12 Adipose gene expression LOC120103502 0.05 0.04 7.9e-03 0.02 -0 0 0 4.2e-03 9.9e-01 1.1e-01 1.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density3.15.111.42.42.32.2-2.02.12.5-3.0-3.42.2-2.1-1.1-0.6
Area under the delay curve0.30.40.90.30.70.7-0.70.70.3-0.7-0.50.6-0.60.21.0
BMI with tail3.110.113.3-3.3-3.4-3.33.4-3.4-3.53.53.5-3.33.6-2.00.2
BMI without tail1.32.75.2-1.8-1.7-1.61.6-1.6-2.31.91.9-1.21.8-0.61.1
Body weight2.611.115.2-3.7-3.9-3.93.7-3.7-3.63.43.3-2.83.3-2.70.3
Weight adjusted by age0.10.20.7-0.3-0.3-0.30.1-0.1-0.1-0.10.3-0.50.1-0.8-0.7
Bone surface0.61.02.50.90.80.8-0.60.71.2-1.5-1.60.6-0.7-1.50.1
Bone volume1.83.06.21.81.71.6-1.51.62.0-2.4-2.51.5-1.6-1.40.1
Breakpoint value in progressive ratio session3.94.37.32.42.12.2-2.22.22.2-2.7-2.32.3-1.8-0.20.8
Number of licking bursts2.42.94.8-2.0-1.8-1.81.8-1.8-2.22.01.7-1.81.7-0.2-0.1
Context. condit. distance diff. score0.30.42.2-0.00.10.10.0-0.00.1-0.5-0.70.30.0-1.5-1.1
Locomotion velocity, session 11.11.22.0-1.2-1.2-1.21.1-1.1-1.41.11.0-0.61.3-0.80.7
Locomotion distance, session 10.40.50.90.80.80.8-0.80.80.8-0.7-0.50.9-0.50.30.2
Locomotion velocity, session 20.60.71.1-1.0-0.9-1.00.9-0.9-1.00.90.8-1.10.8-0.40.4
Locomotion distance, session 20.10.10.90.20.30.3-0.30.30.2-0.2-0.00.3-0.00.10.9
Locomotion velocity, session 30.10.20.60.20.40.3-0.50.50.3-0.3-0.40.1-0.30.5-0.8
Locomotion distance, session 30.70.71.10.71.01.0-1.01.00.7-1.0-0.90.5-0.70.4-0.8
Stereotopy head waving bouts, day 31.11.33.11.01.21.1-1.11.10.8-1.2-1.81.5-1.20.7-0.1
Stereotopy head waving duration, day 30.00.00.1-0.2-0.0-0.10.1-0.1-0.30.0-0.30.1-0.20.0-0.1
Locomotion velocity, session 70.00.00.1-0.00.10.1-0.00.0-0.0-0.2-0.4-0.2-0.1-0.20.3
Locomotion distance, session 70.60.81.9-0.9-0.9-0.81.0-1.0-0.90.90.6-1.41.0-0.5-0.1
Stereotopy head waving bouts, day 70.00.00.1-0.3-0.2-0.20.1-0.1-0.20.30.20.30.20.20.2
Stereotopy head waving duration, day 70.10.10.40.10.20.1-0.20.30.2-0.2-0.20.6-0.40.4-0.4
Locomotion velocity, session 80.20.31.0-0.10.30.3-0.40.4-0.0-0.7-0.80.5-0.1-1.0-0.5
Locomotion distance, session 80.91.42.51.01.21.2-1.21.21.2-1.6-1.51.1-1.1-0.6-0.7
Degree of sensitization distance3.43.45.0-1.8-2.1-2.02.2-2.2-1.82.11.6-1.92.0-1.30.6
Degree of sensitization stereotypy0.40.40.9-0.7-0.7-0.70.6-0.6-0.50.81.0-0.10.60.10.5
Conditioned locomotion1.82.14.11.31.41.4-1.41.41.5-1.8-2.01.8-1.5-0.1-1.1
Cocaine response after cond. corrected0.30.41.4-0.4-0.4-0.40.4-0.4-0.10.30.7-0.40.8-1.20.9
Cocaine response after cond. not corrected0.10.11.10.20.30.2-0.30.30.2-0.10.20.30.00.01.0
Cocaine response before conditioning1.72.17.21.31.31.4-1.41.40.6-0.9-1.31.5-1.92.7-0.5
Saline control response1.82.33.91.51.41.4-1.41.41.7-1.4-1.92.0-2.01.10.3
Bone: connectivity density0.81.24.31.11.01.0-0.80.81.1-1.3-2.11.1-0.8-0.6-0.5
Bone: cortical apparent density0.50.65.5-0.4-0.2-0.20.1-0.0-0.60.4-0.10.90.00.42.4
Bone: cortical area0.20.31.6-0.2-0.2-0.20.2-0.20.3-0.10.7-1.00.7-1.30.4
Bone: cortical porosity0.50.50.80.80.60.7-0.50.60.7-0.8-0.90.7-0.90.1-0.9
Bone: cortical porosity0.30.40.70.70.50.6-0.40.50.6-0.7-0.80.6-0.8-0.1-0.6
Bone: cortical thickness0.30.51.5-0.6-0.5-0.40.3-0.3-0.20.31.1-0.90.8-0.71.2
Bone: cortical thickness1.01.21.91.31.11.2-1.21.31.4-1.2-0.80.9-0.70.31.1
Bone: cortical tissue density0.50.75.8-0.5-0.3-0.30.2-0.2-0.70.5-0.00.80.20.32.4
Condit. Reinf. active minus inactive responses3.64.05.8-2.3-2.1-2.01.9-2.0-2.42.12.3-2.22.1-1.20.9
Condit. Reinf. active-inactive response ratio1.81.93.7-1.7-1.4-1.31.2-1.3-1.91.51.5-1.51.4-0.50.6
Condit. Reinf. active responses1.21.52.3-1.4-1.2-1.31.2-1.2-1.51.41.3-1.21.3-0.60.2
Condit. Reinf. inactive responses0.20.20.50.60.50.4-0.30.40.6-0.3-0.70.6-0.30.4-0.4
Incentive salience index mean1.01.22.3-1.3-1.1-1.11.0-1.0-1.51.31.2-1.10.90.20.2
Condit. Reinf. lever presses0.70.93.60.80.80.8-0.90.90.4-0.6-0.71.1-1.31.9-0.5
Condit. Reinf. active minus inactive responses0.10.10.60.20.10.10.00.1-0.1-0.00.3-0.60.7-0.60.1
Condit. Reinf. active-inactive response ratio0.20.20.4-0.1-0.2-0.10.4-0.3-0.40.20.6-0.60.6-0.6-0.6
Condit. Reinf. active responses0.10.10.40.30.30.2-0.20.30.1-0.00.4-0.10.20.00.7
Condit. Reinf. inactive responses0.30.30.70.40.40.4-0.70.60.6-0.4-0.30.7-0.60.60.8
Condit. Reinf. lever presses0.20.22.20.20.30.3-0.30.30.0-0.30.10.1-0.3-0.21.5
Condit. Reinf. lever reinforcers received0.10.11.10.10.10.00.00.1-0.10.10.5-0.30.4-0.21.1
Conditioned reinforcement - actives1.11.12.41.51.11.1-1.00.91.5-1.2-1.00.9-0.7-0.50.4
Conditioned reinforcement - inactives2.22.54.62.11.91.7-1.71.72.1-1.5-1.30.6-1.41.40.0
Conditioned locomotion3.54.28.02.82.22.0-2.02.02.6-1.4-1.41.4-1.92.12.1
Patch foraging indifference point 0 sec0.60.93.80.60.50.6-0.80.80.6-1.6-0.80.1-0.7-2.0-1.0
Patch foraging indifference point AUC0.50.63.9-0.4-0.3-0.30.4-0.4-0.70.40.4-1.20.6-0.1-2.0
Delay disc. indifference point, 0s delay0.40.41.5-0.8-0.4-0.40.4-0.4-0.70.51.0-0.40.6-0.51.2
Delay disc. indifference point, 16s delay0.80.81.20.91.01.0-1.01.00.9-1.0-0.90.9-1.10.70.5
Delay disc. indifference point, 2s delay0.30.32.6-0.20.30.3-0.40.3-0.1-0.20.10.1-0.40.51.6
Delay disc. indifference point, 24s delay3.73.65.82.02.22.2-2.22.22.1-2.4-1.91.7-1.4-0.20.8
Delay disc. indifference point, 4s delay0.30.31.10.10.40.4-0.40.40.1-0.4-0.50.6-1.10.90.3
Delay disc. indifference point, 8s delay0.70.71.20.50.80.8-0.90.80.6-1.1-0.91.1-0.9-0.21.1
Indifference point function ln k2.02.74.62.11.61.7-1.61.62.1-1.9-1.41.6-1.6-0.11.5
Indifference point function log k2.02.74.62.11.61.7-1.61.62.1-1.9-1.41.6-1.6-0.11.5
Patch foraging total patch changes 0 sec0.60.94.10.70.60.6-0.80.80.7-1.6-0.80.0-0.6-2.0-0.9
Patch foraging total patch changes 12 sec0.60.72.9-0.7-0.6-0.60.5-0.5-0.70.00.5-1.20.4-1.5-1.7
Patch foraging total patch changes 18 sec0.40.52.3-0.5-0.3-0.30.1-0.2-0.8-0.2-0.2-0.80.7-1.2-1.5
Patch foraging total patch changes 24 sec0.30.31.6-0.2-0.1-0.2-0.10.0-0.5-0.30.3-1.10.4-1.3-0.7
Patch foraging total patch changes 6 sec0.40.63.3-0.3-0.3-0.30.1-0.1-0.1-0.30.4-1.50.5-1.2-1.8
Patch foraging time to switch 0 sec0.40.62.8-0.9-0.5-0.50.4-0.4-1.01.10.20.40.31.71.0
Patch foraging water rate 0 sec2.54.07.52.52.12.1-2.02.12.5-2.7-2.11.3-2.0-0.8-0.8
Patch foraging water rate 12 sec0.10.10.60.20.00.0-0.10.10.1-0.30.3-0.3-0.2-0.50.8
Patch foraging water rate 18 sec2.63.55.72.32.02.0-2.12.02.4-2.2-1.41.7-2.10.70.1
Patch foraging water rate 24 sec0.10.10.20.50.20.2-0.20.20.5-0.4-0.30.1-0.2-0.40.2
Patch foraging water rate 6 sec0.60.92.11.41.11.1-0.90.91.5-1.1-0.40.1-0.8-0.10.2
Seeking ratio, delayed vs. immediate footshock1.71.98.3-0.8-1.0-1.01.3-1.3-0.71.41.7-2.91.7-0.6-0.8
Distance traveled before self-admin0.10.10.30.20.10.1-0.00.1-0.2-0.10.20.50.1-0.40.5
Distance traveled after self-admin0.40.54.30.2-0.1-0.1-0.00.00.2-0.8-0.1-0.10.0-2.1-0.6
Extensor digitorum longus weight1.24.66.12.22.32.2-2.52.32.3-2.4-2.42.5-2.20.70.7
Bone: elastic displacement0.80.91.61.01.01.1-1.21.10.9-1.2-1.01.1-0.8-0.10.2
Bone: elastic work1.31.72.91.51.41.5-1.51.51.6-1.7-1.21.1-1.30.00.4
Bone: endosteal estimation0.20.41.30.60.40.4-0.30.30.9-0.9-0.7-0.2-0.2-1.1-1.0
Bone: endosteal perimeter0.10.31.60.10.0-0.00.2-0.10.6-0.4-0.1-0.40.2-1.3-0.8
Epididymis fat weight12.328.639.2-5.8-6.2-6.26.3-6.2-5.65.65.3-4.55.2-3.9-0.8
Delta time in closed arm before/after self-admin0.30.32.00.20.30.3-0.20.20.2-0.3-0.4-0.00.0-0.6-1.4
Delta time in open arm before/after self-admin0.50.51.2-1.0-0.7-0.70.7-0.7-1.10.30.60.20.7-0.80.8
Diff in mean of infusions in LGA sessions0.80.91.91.10.60.7-0.60.60.9-1.2-1.21.4-1.4-0.3-0.2
Delay discount exponential model param0.70.70.9-0.6-0.9-0.91.0-0.9-0.61.00.8-0.80.9-0.4-0.8
Extinction: sum of active levers before priming2.52.54.11.61.71.8-1.81.81.5-2.0-1.51.6-1.60.4-0.7
Active lever presses in extinction session 61.01.02.91.10.91.0-1.01.00.9-1.7-0.70.0-0.5-1.1-1.2
Bone: final force0.30.40.9-0.7-0.7-0.70.6-0.5-0.30.30.7-0.90.5-1.0-0.5
Bone: final moment0.20.41.3-0.6-0.6-0.60.4-0.4-0.10.20.7-1.00.6-1.1-0.4
Food consumed during 24 hour testing period0.60.71.8-0.7-0.7-0.70.7-0.7-0.80.90.9-1.31.00.1-0.9
Glucose0.71.11.7-1.2-1.2-1.21.1-1.2-1.00.90.6-0.51.1-1.30.2
Heart weight4.86.810.1-2.5-2.9-2.92.9-2.9-2.62.72.9-3.22.5-1.6-0.4
Delay discount hyperbolic model param0.50.51.1-0.3-0.8-0.80.8-0.8-0.40.80.6-0.70.8-0.4-1.1
Intermittent access intake day 1-15 change1.31.22.61.00.91.0-1.01.01.2-1.6-1.41.0-1.1-1.30.3
Intermittent access intake escalation1.01.02.31.00.80.8-0.80.81.0-1.5-1.30.7-0.9-1.5-0.4
Intermittent access intake escalation 20.70.77.10.1-0.2-0.20.3-0.30.2-0.6-0.3-0.50.3-2.7-0.2
Intermitt. access day 1 inactive lever presses0.20.20.8-0.6-0.5-0.20.4-0.4-0.60.60.3-0.40.10.9-0.2
Intermitt. access day 15 inactive lever presses0.30.41.90.3-0.3-0.30.4-0.40.20.50.3-0.90.50.5-1.4
Intermitt. access escalation Index0.70.61.7-0.6-0.9-0.70.7-0.7-0.70.71.2-1.30.8-0.70.4
Intermittent access day 1 total infusions1.82.14.61.81.51.5-1.61.61.6-0.9-1.01.2-1.42.10.2
Intermittent access day 15 total infusions1.41.62.51.61.31.2-1.31.31.6-1.4-1.21.2-1.50.30.7
Intermittent access terminal intake (last 3 days)0.91.02.11.40.90.9-1.01.01.3-1.0-0.50.8-1.10.31.0
Intermittent access total infusions2.52.84.52.11.71.7-1.71.72.0-1.4-1.31.6-1.81.60.8
Intermittent access day 1 locomotion2.22.39.71.51.41.5-1.41.41.3-0.4-0.61.1-1.13.11.4
Intermittent access day 15 total locomotion0.10.10.60.2-0.1-0.10.1-0.10.00.40.3-0.30.00.80.4
Intermittent access total locomotion1.11.35.01.40.90.9-0.80.81.1-0.1-0.40.8-1.02.21.7
Intermittent access standard deviation0.30.30.60.40.50.5-0.50.50.5-0.7-0.60.4-0.7-0.4-0.6
Left kidney weight0.10.31.3-0.4-0.7-0.60.6-0.6-0.20.30.6-0.10.4-1.1-0.1
Right kidney weight0.92.54.0-1.4-2.0-2.01.8-1.9-1.21.41.5-1.01.4-2.0-0.7
Cocaine induced anxiety0.60.72.31.10.60.6-0.60.61.1-1.0-1.50.9-0.7-0.3-0.5
Post-drug Anxiety0.50.62.4-0.4-0.8-0.80.8-0.8-0.40.5-0.00.50.5-0.6-1.6
Baseline Anxiety1.51.63.6-1.5-1.1-1.11.1-1.1-1.61.71.9-0.81.50.4-0.2
Tail length0.51.64.60.91.01.0-1.31.20.7-1.2-1.32.1-1.81.30.2
Length with tail0.00.20.3-0.4-0.5-0.60.3-0.3-0.1-0.00.10.6-0.5-0.60.4
Length without tail0.20.32.2-0.2-0.6-0.60.5-0.50.3-0.00.1-0.1-0.2-1.5-0.5
Times rat made contact with spout1.51.83.21.21.31.3-1.31.31.1-1.5-1.81.4-1.50.7-1.0
Lifetime Intake2.62.95.22.11.71.8-1.81.81.9-1.2-1.31.6-1.72.30.6
Liver weight, left1.11.73.2-1.5-1.5-1.41.5-1.4-1.71.41.8-0.70.7-0.50.8
Liver weight, right4.77.79.8-2.9-3.1-3.13.1-3.1-2.72.83.0-2.62.9-2.4-0.7
Locomotor activity1.82.84.1-2.0-2.0-2.02.0-2.0-1.91.81.5-1.31.2-1.0-0.8
Locomotor testing distance1.22.03.2-1.8-1.6-1.61.6-1.7-1.81.41.0-1.01.0-0.8-0.8
Locomotor testing rearing0.20.30.7-0.7-0.5-0.50.6-0.6-0.80.70.4-0.80.30.2-0.6
Locomotion in novel chamber0.40.52.2-0.4-0.3-0.30.2-0.2-0.70.70.7-0.2-0.11.11.5
Locomotion in novel chamber post-restriction0.70.91.4-1.0-1.0-1.01.1-1.1-1.21.21.1-0.60.9-0.20.3
Fecal boli incidents, locomotor time 14.14.46.12.02.42.5-2.42.42.1-2.2-2.32.0-2.11.70.6
Change in fecal boli incidents, locomotor task0.80.72.2-0.6-1.0-0.91.1-1.0-0.60.80.7-0.60.2-0.5-1.5
Time >=10cm from walls, locomotor time 10.20.20.4-0.4-0.3-0.30.3-0.3-0.40.0-0.60.70.1-0.50.6
Bouts of movement, locomotor time 12.83.19.51.61.81.7-1.81.81.6-1.1-1.41.4-1.93.11.1
Total resting periods, locomotor time 12.42.68.41.51.61.5-1.71.61.5-1.0-1.51.3-1.72.90.8
Rest time, locomotor task time 11.51.76.41.11.11.1-1.11.11.1-0.7-1.20.9-1.52.50.9
Distance moved, locomotor task time 11.41.52.6-1.6-1.2-1.31.2-1.2-1.61.01.2-0.71.3-1.6-0.3
Vertical activity count, locomotor time 10.30.31.0-0.8-0.2-0.20.2-0.2-0.80.10.60.00.5-1.00.9
Time >=10cm from walls, locomotor time 20.30.30.90.40.50.6-0.50.50.3-0.3-0.90.5-0.00.90.4
Bouts of movement, locomotor time 20.40.41.20.80.60.5-0.60.60.7-0.3-0.20.0-0.51.11.1
Total resting periods, locomotor time 20.40.51.70.90.70.6-0.70.70.8-0.3-0.3-0.0-0.41.30.7
Rest time, locomotor task time 20.20.20.90.50.30.2-0.30.30.5-0.1-0.5-0.0-0.30.90.5
Distance moved, locomotor task time 20.10.20.4-0.7-0.2-0.30.2-0.2-0.60.30.60.30.1-0.30.4
Vertical activity count, locomotor time 20.20.30.70.30.60.6-0.60.60.3-0.5-0.20.7-0.40.10.9
Light reinforcement 10.10.20.70.00.30.4-0.40.40.1-0.5-0.40.7-0.80.00.1
Light reinforcement 20.50.73.20.40.60.6-0.60.60.5-0.6-1.01.8-1.00.70.3
Bone: marrow area0.20.41.10.60.50.4-0.30.30.9-0.9-0.7-0.1-0.2-1.0-0.9
Bone: maximum diameter0.30.53.80.20.20.1-0.10.10.7-0.9-0.1-0.30.2-1.9-0.7
Bone: maximum force0.10.21.0-0.2-0.2-0.20.1-0.10.4-0.10.3-1.00.1-0.5-0.6
Bone: maximum moment0.10.21.00.0-0.0-0.0-0.10.10.6-0.30.2-1.00.1-0.7-0.4
Mean time between licks in bursts0.81.21.9-1.3-1.1-1.11.1-1.1-1.41.11.1-1.21.1-0.7-0.1
Mean num. licks in bursts4.65.58.02.62.42.4-2.42.42.7-2.8-2.62.6-2.50.4-0.4
Cd content in liver0.70.81.8-1.0-0.8-0.80.8-0.7-1.00.60.7-1.41.2-0.90.0
Co content in liver1.11.32.21.31.21.2-1.21.21.2-1.5-0.91.4-1.5-0.20.1
Cu content in liver1.41.73.6-1.4-1.5-1.51.5-1.5-1.41.10.7-0.81.2-1.9-0.1
Fe content in liver0.30.31.70.30.20.2-0.20.20.6-0.6-1.00.1-0.5-0.3-1.3
K content in liver2.22.23.3-1.6-1.6-1.51.4-1.4-1.81.81.5-1.41.40.4-1.4
Mg content in liver1.01.12.1-1.1-1.2-1.11.0-1.0-1.41.21.0-0.81.1-0.1-0.6
Mn content in liver0.10.21.6-0.00.00.1-0.10.1-0.30.10.20.2-0.10.31.3
Na content in liver0.80.92.20.90.90.9-1.01.00.8-0.6-0.71.0-1.01.5-0.6
Rb content in liver0.70.93.9-0.9-0.7-0.70.5-0.5-1.30.60.5-1.20.70.0-2.0
Se content in liver0.30.30.8-0.5-0.6-0.60.7-0.7-0.50.90.4-0.00.20.60.4
Sr content in liver0.80.71.30.80.90.9-0.80.80.7-0.7-1.00.9-1.10.70.5
Zn content in liver5.76.38.4-2.8-2.8-2.92.9-2.9-2.72.72.7-2.22.2-1.6-0.4
Bone: minimum diameter1.12.14.2-1.4-1.5-1.51.5-1.5-0.81.01.5-2.01.5-2.10.5
Time in familiar zone, hab. session 10.40.40.6-0.8-0.5-0.60.7-0.7-0.60.80.7-0.40.5-0.30.6
Time in novel zone, hab. session 10.60.61.1-0.8-0.9-0.80.8-0.8-0.60.40.4-1.00.7-1.0-0.3
Total zone transitions, hab. session 10.30.40.70.70.60.7-0.60.60.5-0.5-0.60.6-0.60.7-0.9
Total locomotion distance, hab. session 10.71.01.31.21.11.1-1.01.00.9-0.9-0.81.2-1.10.8-0.1
Locomotion velocity, hab. session 11.31.82.51.61.51.5-1.41.41.2-1.1-1.01.5-1.41.5-0.3
Time in familiar zone, hab. session 20.30.31.50.40.60.5-0.50.50.6-0.2-0.4-0.1-0.41.20.6
Time in novel zone, hab. session 21.71.74.5-1.3-1.4-1.41.4-1.4-1.40.90.8-0.51.4-2.10.1
Total zone transitions, hab. session 20.60.81.70.80.80.9-0.90.90.7-0.9-1.00.7-0.90.8-1.3
Total locomotion distance, hab. session 20.70.92.60.90.90.9-0.80.80.8-0.9-1.10.8-1.00.8-1.6
Locomotion velocity, hab. session 20.91.33.71.01.01.0-1.01.00.9-1.0-1.20.9-1.20.9-1.9
Novel to familiar place preference ratio0.30.41.7-0.3-0.4-0.40.4-0.4-0.40.20.5-1.30.6-1.0-0.0
Novelty place preference0.70.72.5-0.7-0.8-0.80.7-0.7-0.70.50.9-1.60.9-1.10.1
Time in novel zone, NPP test0.70.72.1-0.6-0.7-0.70.7-0.7-0.70.50.7-1.50.9-1.30.3
Total zone transitions, NPP test0.50.72.10.70.70.8-0.80.80.5-0.8-1.01.1-0.70.6-1.4
Total locomotion distance, NPP test1.11.62.71.21.21.2-1.21.11.0-1.2-1.61.6-1.30.7-1.3
Locomotion velocity, NPP test1.62.23.31.51.41.5-1.41.41.2-1.5-1.71.8-1.71.1-1.6
Intraocular pressure2.43.37.2-1.9-1.8-1.81.7-1.8-1.61.41.8-1.62.2-2.71.0
Delta distance traveled before/after self-admin0.70.82.7-0.8-0.8-0.80.7-0.8-0.5-0.00.3-1.10.4-1.6-1.4
Delta ambulatory time before/after self-admin0.30.32.0-0.0-0.10.0-0.00.00.3-0.7-0.4-0.4-0.1-1.4-1.0
Parametrial fat weight10.720.927.5-5.1-5.2-5.25.1-5.1-5.04.95.1-3.44.4-3.20.7
Pavlov. Cond. lever latency0.40.41.7-0.4-0.4-0.40.5-0.5-0.10.30.6-1.00.8-1.30.8
Pavlov. Cond. magazine entry latency0.30.40.90.70.60.6-0.50.50.4-0.5-0.70.8-0.30.4-0.9
Pavlov. Cond. change in total contacts0.80.91.50.91.01.0-1.01.00.6-1.0-0.81.2-0.80.11.2
Pavlov. Cond. index score0.60.71.70.80.70.7-0.70.70.4-0.6-0.91.3-0.91.2-0.7
Pavlov. Cond. latency score0.50.61.80.70.60.6-0.60.60.3-0.4-0.91.1-0.81.3-0.9
Pavlov. Cond. lever contacts0.70.81.80.80.70.8-0.80.80.5-0.7-0.81.3-1.01.1-0.9
Pavlov. Cond. magazine entry number0.50.61.1-0.9-0.8-0.80.7-0.7-0.40.60.9-1.00.5-0.81.0
Pavlov. Cond. intertrial magazine entries1.41.83.41.11.31.4-1.31.31.3-1.5-1.61.8-1.60.20.4
Pavlov. Cond. lever-magazine prob. diff.1.11.32.51.21.11.1-1.11.10.8-1.0-1.31.6-1.21.2-0.8
Pavlov. Cond. response bias1.72.13.31.61.51.5-1.51.51.2-1.5-1.61.8-1.50.9-1.0
Pavlov. Cond. lever latency0.20.20.5-0.5-0.4-0.40.4-0.4-0.30.50.6-0.10.7-0.40.6
Pavlov. Cond. magazine entry latency1.01.22.0-1.1-1.2-1.11.0-1.0-1.11.00.8-1.41.3-0.7-1.1
Pavlov. Cond. change in total contacts0.50.71.5-0.8-1.0-0.90.9-1.0-0.90.80.6-1.20.8-0.4-0.5
Pavlov. Cond. index score0.20.21.1-0.4-0.5-0.40.4-0.4-0.50.30.1-0.80.30.0-1.0
Pavlov. Cond. latency score0.20.21.3-0.4-0.4-0.30.3-0.4-0.40.30.1-0.80.3-0.0-1.1
Pavlov. Cond. lever contacts0.10.10.8-0.2-0.3-0.20.3-0.2-0.40.10.1-0.5-0.10.1-0.9
Pavlov. Cond. magazine entry number1.31.62.31.41.41.4-1.41.41.3-1.3-0.81.5-1.40.71.0
Pavlov. Cond. intertrial magazine entries0.30.43.90.10.10.10.00.10.2-0.10.30.5-0.1-0.62.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.6-0.6-0.50.5-0.6-0.70.50.3-0.90.5-0.0-0.9
Pavlov. Cond. response bias0.10.21.4-0.3-0.4-0.20.3-0.3-0.40.2-0.0-0.60.20.0-1.2
Time in closed arm before self-admin0.30.30.8-0.2-0.8-0.70.8-0.8-0.00.60.20.2-0.0-0.1-0.9
Time in closed arm after self-admin1.41.42.0-0.9-1.4-1.31.4-1.4-0.41.41.4-1.30.9-0.8-1.2
Time in open arm before self-admin0.50.51.10.31.00.8-1.01.00.3-0.5-0.10.6-0.51.10.7
Time in open arm after self-admin1.21.32.50.61.31.2-1.31.30.2-1.2-1.01.6-0.90.81.5
Bone: periosteal estimation0.20.42.40.40.30.3-0.20.20.9-0.9-0.3-0.50.1-1.5-0.4
Bone: periosteal perimeter0.10.21.40.10.10.0-0.00.10.6-0.60.0-0.50.1-1.2-0.8
Bone: post-yield work1.11.52.41.31.41.3-1.21.21.6-1.1-1.40.4-1.01.0-1.5
Progressive ratio test 1 active lever presses0.90.98.10.60.60.7-0.60.60.30.3-0.30.3-0.92.80.4
Progressive ratio test 1 breakpoint0.90.96.30.60.60.7-0.80.80.40.1-0.30.6-1.02.50.5
Progressive ratio test 1 inactive lever presses1.51.712.11.00.90.9-1.01.00.7-0.0-0.9-0.3-1.23.5-0.7
Progressive ratio test 2 active lever presses1.01.11.71.11.11.2-1.11.01.1-0.8-0.81.3-0.90.91.2
Progressive ratio test 2 breakpoint1.41.52.11.31.31.4-1.31.31.3-1.1-1.11.5-1.20.81.3
Progressive ratio test 2 inactive lever presses0.60.61.81.00.91.0-0.90.90.9-0.4-0.5-0.3-0.31.3-0.1
Incentive Sensitization - Responses1.31.35.01.00.91.0-0.90.81.2-1.1-0.51.2-0.4-1.22.2
Incentive Sensitization - Breakpoint1.21.25.70.90.80.9-0.70.71.1-1.0-0.41.1-0.4-1.32.4
Sum of active levers in priming session hrs 5-61.41.42.71.11.41.5-1.51.51.1-1.6-1.00.9-0.70.1-0.3
Progressive ratio0.50.62.9-0.6-0.6-0.60.6-0.6-0.40.80.4-0.70.9-0.2-1.7
Food seeking constrained by brief footshock5.56.710.32.62.72.7-2.92.92.7-3.1-3.22.5-2.61.0-0.7
Seeking ratio, punishment vs. effort1.92.33.91.51.71.7-1.71.71.4-2.0-1.71.4-1.80.50.8
Retroperitoneal fat weight24.279.6102.9-9.8-10.1-10.110.0-10.1-9.49.59.6-8.18.8-6.10.8
Reaction time number correct0.10.20.6-0.5-0.6-0.50.3-0.3-0.50.1-0.1-0.20.3-0.80.5
Reaction time mean minus median0.81.13.2-1.0-1.1-1.01.0-1.1-0.80.90.60.31.1-1.21.8
Reaction time mean minus median AUC1.01.31.7-1.2-1.3-1.31.2-1.3-0.91.11.0-0.51.3-1.31.2
Reaction time num false alarms0.91.22.4-1.3-1.1-1.11.2-1.2-1.00.90.8-1.10.9-1.0-1.6
Reaction time num false alarms AUC0.70.91.5-1.2-1.1-1.11.1-1.1-0.90.80.8-0.70.8-1.0-1.0
Reaction time trials correct on left0.10.20.6-0.5-0.6-0.50.3-0.3-0.50.1-0.1-0.20.3-0.80.5
Reaction time trials on left0.20.20.7-0.5-0.6-0.50.3-0.3-0.50.2-0.0-0.20.4-0.80.7
Reaction time mean0.50.75.8-0.1-0.2-0.10.4-0.40.10.20.10.60.4-1.12.4
Reaction time mean AUC0.50.65.7-0.0-0.1-0.10.4-0.30.30.20.10.40.5-1.02.4
Median of all reaction times0.50.76.50.40.30.4-0.00.10.6-0.2-0.30.80.1-0.72.6
Reaction time omissions0.60.82.0-0.8-1.1-1.00.9-1.0-0.71.10.6-0.51.4-0.30.8
Reaction time false alarm rate0.40.51.4-0.8-0.6-0.70.8-0.8-0.50.70.8-0.50.5-0.4-1.2
Reaction time premature initiation rate0.40.51.70.60.20.3-0.50.40.4-0.5-0.90.8-1.11.0-1.3
Reaction time premature initiations0.20.30.90.3-0.00.1-0.30.30.2-0.4-0.90.7-0.70.6-0.8
Std. dev. reaction times0.70.93.4-0.7-0.8-0.80.9-0.9-0.50.70.50.21.1-1.51.9
Reaction time trials completed0.20.20.7-0.5-0.6-0.50.3-0.3-0.50.2-0.0-0.20.4-0.80.7
Reaction time trials AUC0.20.30.9-0.6-0.6-0.60.4-0.4-0.60.20.0-0.10.4-0.80.9
Run reversals in cocaine runway, females0.60.61.40.60.70.7-0.80.80.6-1.1-0.80.3-0.7-0.4-1.2
Run reversals in cocaine runway, males0.20.20.40.50.50.5-0.60.60.6-0.70.10.3-0.4-0.10.3
Latency to leave start box in cocaine runway1.01.13.60.60.70.7-0.80.80.8-1.3-1.70.9-0.6-0.7-1.9
Latency to leave start box in cocaine runway, F0.60.74.10.40.50.5-0.60.60.5-0.9-0.7-0.0-0.0-0.9-2.0
Latency to leave start box in cocaine runway, M1.51.54.60.81.01.0-1.01.00.8-1.5-2.12.0-1.2-0.2-0.8
Std. dev. time between licks in bursts0.10.10.3-0.0-0.2-0.20.2-0.2-0.1-0.00.0-0.50.2-0.40.2
Total sessions with >9 infusions5.35.817.82.52.42.5-2.52.52.3-1.3-1.42.2-2.44.21.2
Short access day 1 total inactive lever presses2.52.810.71.71.51.7-1.81.81.5-0.9-1.30.6-1.73.30.1
Short access day 10 total inactive lever presses0.40.52.6-0.5-0.6-0.60.6-0.6-0.50.5-0.2-0.70.60.0-1.6
Short access day 1 total infusions2.52.610.51.71.41.6-1.61.61.4-0.7-1.21.2-1.63.20.4
Short access day 10 total infusions3.84.28.52.22.12.2-2.32.32.1-1.4-1.52.3-2.02.90.1
Short access total infusions3.13.57.82.11.82.0-2.12.11.9-1.2-1.42.0-1.92.80.1
Short access day 1 locomotion2.83.06.62.11.61.6-1.81.71.9-1.0-1.31.7-1.82.61.4
Short access day 10 total locomotion0.70.82.50.80.70.8-0.50.50.7-0.1-0.81.2-0.81.61.4
Short access total locomotion3.03.18.91.91.61.7-1.71.71.7-0.7-1.21.8-1.53.01.8
One hour access (0.3 mA shock)2.83.35.12.32.02.1-1.81.82.2-1.9-2.01.4-1.70.50.9
Compulsive drug intake0.40.41.0-0.8-0.5-0.50.6-0.6-0.70.50.2-1.00.8-0.5-0.5
One hour access (shock baseline)3.03.55.52.32.02.1-2.01.92.2-1.6-1.61.7-1.91.60.9
Social response proportion0.10.10.40.40.00.1-0.10.20.4-0.30.00.2-0.5-0.40.6
Social responses0.50.61.1-0.8-0.9-0.90.6-0.6-0.80.60.8-0.90.9-1.0-0.1
Social time0.91.12.60.90.80.8-0.90.90.7-0.5-0.61.6-1.51.51.4
Soleus weight3.39.714.83.13.33.2-3.73.43.1-3.9-3.53.6-3.41.0-0.5
Bone: stiffness0.71.23.2-1.0-1.0-1.11.1-1.1-0.40.81.1-1.81.0-1.1-1.0
Tibialis anterior weight1.34.47.12.22.22.2-2.42.32.2-2.2-2.22.7-2.11.10.1
Time to tail flick, vehicle, before self-admin0.30.31.5-0.1-0.3-0.20.2-0.2-0.30.70.60.4-0.01.01.2
Time to tail flick, vehicle, after self-admin3.63.86.0-2.4-2.1-2.02.1-2.0-2.32.11.9-2.31.9-0.2-0.7
Time to tail flick, test, before self-admin2.92.95.82.21.71.7-1.81.82.4-1.7-1.21.8-1.70.70.8
Time to tail flick, test, after self-admin2.32.43.61.31.71.8-1.71.81.5-1.3-1.31.9-1.71.41.0
Delta time to tail flick, vehicle, before/after SA1.51.52.5-1.6-1.1-1.11.2-1.2-1.41.10.8-1.61.3-0.6-1.3
Delta time to tail flick, test, before/after SA1.41.32.10.71.31.4-1.41.40.5-0.9-1.31.1-1.21.50.3
Tibia length1.95.37.0-2.5-2.6-2.62.4-2.5-2.52.52.6-2.22.4-1.40.7
Ambulatory time before self-admin0.10.10.60.10.00.00.1-0.10.0-0.00.40.40.2-0.50.8
Ambulatory time after self-admin0.60.65.7-0.2-0.4-0.30.4-0.4-0.1-0.50.4-0.60.5-2.4-0.4
Bone: tissue strength0.20.21.80.1-0.1-0.10.1-0.20.3-0.10.4-0.2-0.3-0.61.3
Total heroin consumption5.56.411.13.32.72.7-2.82.83.1-2.9-2.32.5-2.01.11.2
Bone: trabecular number3.04.89.22.42.32.2-2.02.12.3-2.7-3.02.4-2.2-0.3-0.6
Bone: trabecular spacing1.62.05.0-1.2-1.1-1.11.0-1.0-1.41.92.2-1.91.61.01.1
Bone: trabecular thickness1.61.94.41.31.11.0-0.81.01.5-1.9-2.11.7-1.4-1.4-0.2
Bone: trabecular tissue density0.20.31.6-0.5-0.5-0.40.3-0.4-0.60.2-0.20.5-0.00.0-1.2
Water consumed over 24 hours0.10.10.5-0.20.00.0-0.00.0-0.2-0.3-0.5-0.50.2-0.4-0.7
Number of responses in last shaping day1.71.83.51.71.41.6-1.41.41.6-0.9-1.21.2-1.01.90.1