LOC120103502

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC120103502 0.07 0.03 2.5e-09 0.07 0.06 0.07 0.07 2.1e-10 5.3e-09 2.0e-11 4.4e-11
2 PL gene expression LOC120103502 0.28 0.1 9.2e-14 0.12 0.12 0.1 0.12 3.3e-13 1.5e-12 1.8e-11 3.1e-13
3 OFC mRNA stability LOC120103502 0.26 0.14 6.4e-05 0.18 0.18 0.13 0.19 4.2e-05 3.9e-05 5.3e-04 3.3e-05
4 PL mRNA stability LOC120103502 0.04 0.03 7.4e-05 0.03 0.03 0.03 0.03 1.7e-04 4.3e-04 2.1e-04 7.2e-04
5 IL gene expression LOC120103502 0.3 0.13 9.4e-06 0.21 0.2 0.18 0.2 7.7e-06 1.9e-05 4.9e-05 1.6e-05
6 IL mRNA stability LOC120103502 0.29 0.11 3.4e-07 0.22 0.26 0.24 0.23 4.5e-06 8.0e-07 2.3e-06 2.5e-06
7 Brain mRNA stability LOC120103502 0.06 0.03 1.1e-06 0.06 0.07 0.06 0.06 4.0e-06 4.2e-07 1.8e-06 2.0e-06
8 LHb mRNA stability LOC120103502 0.2 0.13 4.0e-04 0.1 0.15 0.15 0.11 3.0e-03 1.9e-04 2.1e-04 1.3e-03
9 BLA gene expression LOC120103502 0.11 0.06 9.9e-05 0.05 0.06 0.05 0.04 8.2e-04 7.2e-04 1.2e-03 2.9e-03
10 OFC gene expression LOC120103502 0.45 0.16 9.8e-06 0.21 0.26 0.23 0.23 8.1e-06 6.2e-07 4.4e-06 4.0e-06
11 IC mRNA stability LOC120103502 0.13 0.07 1.4e-03 0.01 0.04 0.06 0.01 1.6e-01 5.7e-03 2.0e-03 1.5e-01
12 Brain gene expression LOC120103502 0.48 0.1 4.1e-07 0.02 0.08 0.1 0.07 3.4e-03 3.1e-08 6.6e-10 3.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density2.34.211.51.7-1.9-2.01.71.8-2.9-1.8-2.8-1.4-0.53.40.6
Area under the delay curve0.30.50.80.7-0.7-0.70.30.8-0.9-0.9-0.6-0.6-0.8-0.10.5
BMI with tail2.69.112.6-3.53.03.0-3.5-3.02.93.52.73.13.1-1.1-3.0
BMI without tail1.37.010.7-3.22.72.6-2.9-2.82.33.01.92.43.3-0.5-2.9
Body weight1.87.710.8-3.23.13.0-3.3-3.02.52.62.42.53.0-2.2-2.1
Weight adjusted by age0.00.10.10.30.1-0.30.10.00.1-0.1-0.1-0.30.0-0.4-0.4
Bone surface0.30.64.10.3-0.5-0.40.30.4-1.1-0.3-1.1-0.20.32.0-0.2
Bone volume1.02.16.91.1-1.3-1.41.11.2-2.0-1.2-1.9-1.0-0.42.60.3
Breakpoint value in progressive ratio session1.42.58.11.2-1.8-1.91.61.6-1.9-1.1-1.4-0.5-1.02.8-0.4
Number of licking bursts1.02.94.1-2.01.82.0-1.9-1.81.81.71.71.61.5-1.4-0.8
Context. condit. distance diff. score0.20.20.70.3-0.1-0.30.10.1-0.50.0-0.8-0.40.70.8-0.3
Locomotion velocity, session 11.01.11.8-1.40.91.1-1.0-1.00.81.20.91.31.2-0.0-1.0
Locomotion distance, session 10.30.40.60.5-0.7-0.80.80.6-0.8-0.5-0.5-0.1-0.50.80.0
Locomotion velocity, session 20.50.71.4-0.70.90.9-0.9-0.90.90.80.70.60.6-1.2-0.2
Locomotion distance, session 20.10.10.4-0.1-0.2-0.20.40.2-0.3-0.00.10.5-0.40.6-0.0
Locomotion velocity, session 30.10.10.20.4-0.2-0.50.50.3-0.4-0.4-0.5-0.4-0.20.3-0.0
Locomotion distance, session 30.60.71.50.8-0.8-0.90.90.9-1.0-0.7-0.9-0.3-0.71.20.3
Stereotopy head waving bouts, day 31.31.63.01.2-1.3-1.31.01.3-1.5-1.3-1.7-1.7-0.51.00.7
Stereotopy head waving duration, day 30.10.10.40.1-0.1-0.0-0.00.0-0.1-0.2-0.3-0.60.1-0.60.4
Locomotion velocity, session 70.10.10.40.3-0.1-0.10.20.1-0.3-0.1-0.3-0.0-0.10.60.2
Locomotion distance, session 70.50.61.5-0.90.70.9-0.9-0.90.61.00.61.20.70.2-0.4
Stereotopy head waving bouts, day 70.00.10.1-0.30.30.2-0.2-0.10.10.10.20.20.3-0.3-0.4
Stereotopy head waving duration, day 70.00.00.30.10.0-0.10.10.1-0.1-0.3-0.0-0.3-0.0-0.5-0.1
Locomotion velocity, session 80.10.20.70.4-0.1-0.40.50.2-0.5-0.1-0.8-0.50.30.40.0
Locomotion distance, session 81.01.42.31.3-1.1-1.41.31.1-1.3-1.0-1.5-1.4-0.61.20.3
Degree of sensitization distance3.23.44.6-2.11.92.2-2.1-2.01.82.01.71.91.9-0.9-1.3
Degree of sensitization stereotypy0.60.71.3-1.00.90.8-0.6-0.60.80.71.11.10.4-0.5-0.9
Conditioned locomotion1.21.43.10.9-1.0-1.31.01.0-1.7-1.2-1.8-1.30.11.60.2
Cocaine response after cond. corrected0.40.61.8-0.80.30.3-0.3-0.40.40.90.81.40.21.2-1.2
Cocaine response after cond. not corrected0.10.20.9-0.1-0.3-0.20.30.2-0.10.10.30.6-0.50.9-0.3
Cocaine response before conditioning1.82.24.41.5-1.2-1.11.41.3-1.4-2.0-1.4-1.9-1.2-0.82.1
Saline control response1.21.73.21.3-1.2-1.21.31.2-1.8-1.8-1.6-1.4-0.90.41.2
Bone: connectivity density0.81.27.00.4-0.6-0.70.50.6-1.7-0.5-1.6-0.20.42.6-0.2
Bone: cortical apparent density0.10.10.8-0.50.10.10.1-0.0-0.5-0.2-0.10.30.10.9-0.2
Bone: cortical area0.20.30.8-0.30.30.3-0.2-0.30.70.80.90.9-0.1-0.1-0.6
Bone: cortical porosity0.30.41.20.5-0.4-0.40.30.5-0.4-0.8-0.5-1.1-0.3-0.80.6
Bone: cortical porosity0.40.51.30.7-0.6-0.60.50.7-0.7-0.8-0.9-1.1-0.2-0.20.6
Bone: cortical thickness0.40.61.9-0.60.50.6-0.3-0.61.00.81.41.4-0.2-0.5-0.5
Bone: cortical thickness0.50.61.60.8-0.9-0.81.00.8-0.8-0.5-0.40.2-0.91.30.3
Bone: cortical tissue density0.10.20.8-0.70.30.3-0.1-0.2-0.4-0.0-0.10.40.30.9-0.2
Condit. Reinf. active minus inactive responses3.54.05.6-2.22.12.2-2.0-2.02.42.22.42.21.3-1.1-1.4
Condit. Reinf. active-inactive response ratio1.61.72.4-1.41.41.4-1.3-1.21.61.51.51.40.8-0.7-0.9
Condit. Reinf. active responses1.21.52.1-1.41.21.3-1.2-1.31.31.41.41.41.0-0.4-0.9
Condit. Reinf. inactive responses0.20.21.00.2-0.4-0.40.30.2-0.6-0.2-0.6-0.20.31.0-0.1
Incentive salience index mean0.81.01.7-1.11.11.1-1.0-1.11.31.01.20.90.6-0.9-0.5
Condit. Reinf. lever presses0.71.11.91.2-1.0-1.01.10.9-0.8-1.4-0.8-1.3-1.1-0.11.3
Condit. Reinf. active minus inactive responses0.40.61.7-0.70.30.4-0.3-0.20.61.20.71.30.40.9-1.1
Condit. Reinf. active-inactive response ratio0.20.40.8-0.60.40.5-0.5-0.30.70.90.80.80.30.0-0.9
Condit. Reinf. active responses0.20.31.1-0.50.20.3-0.1-0.20.50.80.81.00.00.5-0.7
Condit. Reinf. inactive responses0.00.10.30.2-0.2-0.20.50.1-0.3-0.3-0.00.0-0.30.30.2
Condit. Reinf. lever presses0.10.10.50.1-0.3-0.20.40.3-0.0-0.30.2-0.0-0.7-0.10.4
Condit. Reinf. lever reinforcers received0.30.41.4-0.70.30.5-0.3-0.30.60.90.91.20.10.4-0.6
Conditioned reinforcement - actives0.72.85.81.8-2.0-2.11.71.8-1.7-1.3-1.3-1.1-1.62.40.4
Conditioned reinforcement - inactives1.02.84.12.0-1.9-1.71.71.7-1.3-1.4-1.3-1.4-2.01.52.0
Conditioned locomotion1.82.75.31.6-1.9-1.41.31.7-1.5-1.6-1.4-1.6-1.91.12.3
Patch foraging indifference point 0 sec0.10.40.60.6-0.7-0.70.80.6-0.8-0.6-0.8-0.4-0.60.80.3
Patch foraging indifference point AUC0.10.30.8-0.30.40.4-0.7-0.40.80.90.40.50.7-0.2-0.4
Delay disc. indifference point, 0s delay0.30.30.8-0.50.30.4-0.8-0.40.60.50.90.7-0.0-0.8-0.5
Delay disc. indifference point, 16s delay0.60.91.41.1-0.9-1.00.71.0-1.1-1.2-0.9-0.9-1.00.00.7
Delay disc. indifference point, 2s delay0.20.20.90.2-0.4-0.2-0.20.4-0.1-0.40.0-0.4-0.6-1.00.5
Delay disc. indifference point, 24s delay2.53.911.01.8-2.1-2.42.12.2-2.3-1.4-1.9-0.9-1.53.30.1
Delay disc. indifference point, 4s delay0.70.72.00.7-0.4-0.40.00.5-0.6-1.2-0.7-1.2-0.7-1.41.1
Delay disc. indifference point, 8s delay0.40.71.50.8-0.8-1.00.50.9-1.2-1.0-1.0-0.7-0.60.50.1
Indifference point function ln k0.72.13.01.3-1.7-1.41.71.6-1.7-1.4-1.2-0.8-1.51.60.9
Indifference point function log k0.72.13.01.3-1.7-1.41.71.6-1.7-1.4-1.2-0.8-1.51.60.9
Patch foraging total patch changes 0 sec0.10.40.60.6-0.7-0.70.70.7-0.7-0.5-0.7-0.3-0.60.80.3
Patch foraging total patch changes 12 sec0.20.21.2-0.20.50.5-0.5-0.50.60.30.40.20.3-1.10.0
Patch foraging total patch changes 18 sec0.10.20.4-0.40.30.2-0.3-0.20.20.7-0.10.50.60.6-0.6
Patch foraging total patch changes 24 sec0.00.10.3-0.30.30.2-0.3-0.30.50.40.50.50.00.1-0.3
Patch foraging total patch changes 6 sec0.10.10.4-0.00.30.1-0.3-0.30.60.50.40.4-0.1-0.5-0.3
Patch foraging time to switch 0 sec0.00.10.3-0.40.60.3-0.4-0.40.10.0-0.1-0.30.5-0.1-0.2
Patch foraging water rate 0 sec0.93.54.92.0-2.2-2.02.02.1-2.0-1.8-1.7-1.3-1.91.81.3
Patch foraging water rate 12 sec0.00.10.40.0-0.10.10.20.10.1-0.10.50.4-0.6-0.60.4
Patch foraging water rate 18 sec1.43.26.02.1-2.1-1.82.11.9-1.6-2.0-1.1-1.2-2.40.31.8
Patch foraging water rate 24 sec0.00.10.10.3-0.3-0.20.00.3-0.3-0.2-0.20.0-0.30.30.3
Patch foraging water rate 6 sec0.71.02.61.1-1.1-1.01.21.2-0.7-0.9-0.3-0.3-1.60.80.7
Seeking ratio, delayed vs. immediate footshock1.21.73.8-1.01.21.2-1.4-1.12.01.71.71.30.5-0.6-1.2
Distance traveled before self-admin0.00.10.2-0.30.10.30.1-0.30.10.30.20.30.40.5-0.5
Distance traveled after self-admin0.30.52.8-0.30.30.1-0.2-0.60.30.50.40.70.31.0-1.7
Extensor digitorum longus weight1.24.76.42.2-2.4-2.52.32.2-2.5-2.2-2.3-2.0-1.92.01.3
Bone: elastic displacement0.81.02.60.9-1.0-1.11.21.1-1.1-0.8-1.0-0.6-0.91.60.2
Bone: elastic work1.52.02.81.6-1.5-1.51.71.6-1.4-1.3-1.3-1.3-1.51.50.8
Bone: endosteal estimation0.10.31.20.6-0.6-0.60.30.5-0.4-0.2-0.8-0.8-0.01.1-0.2
Bone: endosteal perimeter0.00.00.10.1-0.2-0.1-0.20.1-0.00.1-0.3-0.30.30.0-0.1
Epididymis fat weight8.844.455.7-7.57.37.4-7.2-7.26.56.56.46.56.8-5.5-4.4
Delta time in closed arm before/after self-admin0.30.31.00.4-0.6-0.40.70.6-0.6-0.1-0.40.2-0.41.00.2
Delta time in open arm before/after self-admin1.11.32.4-1.31.21.1-1.4-1.10.91.10.91.11.6-0.8-1.1
Diff in mean of infusions in LGA sessions0.10.10.30.0-0.1-0.10.0-0.3-0.6-0.6-0.4-0.20.3-0.0-0.3
Delay discount exponential model param0.71.01.5-1.01.11.1-0.6-1.21.21.21.00.91.0-0.2-0.8
Extinction: sum of active levers before priming1.11.73.31.2-1.4-1.81.41.5-1.6-1.4-1.4-1.1-1.01.1-0.1
Active lever presses in extinction session 61.11.13.61.1-1.1-1.41.10.9-0.9-0.6-0.7-0.2-1.01.9-1.0
Bone: final force0.20.40.8-0.50.70.6-0.6-0.80.70.50.70.40.4-0.9-0.4
Bone: final moment0.20.20.4-0.40.50.4-0.4-0.60.60.50.60.40.2-0.6-0.5
Food consumed during 24 hour testing period0.40.71.6-0.90.81.0-0.7-0.80.80.90.91.30.6-0.7-0.4
Glucose1.32.03.8-1.81.51.5-1.5-1.50.71.50.91.81.90.2-1.2
Heart weight1.42.32.9-1.71.51.7-1.7-1.61.71.61.51.31.4-1.3-0.9
Delay discount hyperbolic model param0.40.50.8-0.70.70.7-0.2-0.80.90.90.70.70.70.1-0.6
Intermittent access intake day 1-15 change0.21.12.50.9-1.1-1.20.61.0-1.6-1.1-1.3-1.0-0.31.30.1
Intermittent access intake escalation0.10.81.90.8-0.9-1.00.40.8-1.4-1.0-1.2-0.9-0.21.00.0
Intermittent access intake escalation 20.30.51.80.4-0.7-0.80.10.4-0.9-0.4-0.8-0.40.21.3-0.8
Intermitt. access day 1 inactive lever presses0.00.20.80.00.00.5-0.4-0.30.50.20.30.0-0.1-0.90.8
Intermitt. access day 15 inactive lever presses0.10.31.00.20.20.5-0.7-0.40.70.40.2-0.10.1-0.81.0
Intermitt. access escalation Index0.61.82.8-1.41.71.4-1.5-1.51.61.51.31.11.3-0.8-0.9
Intermittent access day 1 total infusions0.72.24.71.6-1.5-1.31.31.4-1.0-1.6-1.1-1.8-1.8-0.22.2
Intermittent access day 15 total infusions1.02.33.81.6-1.6-1.51.21.5-1.6-1.9-1.5-2.0-1.30.41.5
Intermittent access terminal intake (last 3 days)1.52.64.01.9-1.8-1.61.41.6-1.5-2.0-1.2-1.9-1.90.21.7
Intermittent access total infusions3.84.57.92.3-2.3-1.92.02.1-1.9-2.4-1.7-2.4-2.40.22.8
Intermittent access day 1 locomotion1.32.38.81.4-1.4-0.91.61.5-0.6-1.3-0.5-1.4-2.3-0.03.0
Intermittent access day 15 total locomotion0.10.42.70.3-0.20.10.00.20.0-0.40.2-0.3-0.8-1.21.6
Intermittent access total locomotion2.53.010.21.7-1.7-1.11.41.6-1.2-1.9-1.0-1.7-2.3-0.73.2
Intermittent access standard deviation0.21.22.01.2-1.1-1.00.80.9-1.4-1.4-1.3-1.3-0.70.21.0
Left kidney weight0.11.02.2-1.21.21.0-1.2-1.20.60.80.60.81.5-0.6-0.9
Right kidney weight0.43.03.7-1.91.91.9-1.9-1.91.61.81.51.81.9-1.4-1.3
Cocaine induced anxiety0.41.02.50.6-0.9-0.80.60.8-1.5-1.0-1.6-1.10.11.40.3
Post-drug Anxiety1.11.23.3-1.41.21.1-1.3-1.10.60.90.50.71.8-0.3-1.2
Baseline Anxiety3.25.38.0-2.22.52.4-2.2-2.42.82.42.72.21.9-2.1-1.6
Tail length0.10.61.30.5-0.5-0.71.00.5-1.1-1.1-0.9-0.9-0.40.00.5
Length with tail0.10.32.1-0.10.40.3-0.0-0.3-0.2-0.60.0-0.30.1-1.50.6
Length without tail0.10.32.10.3-0.0-0.10.00.2-0.2-0.60.0-0.4-0.4-1.40.6
Times rat made contact with spout1.82.13.31.6-1.4-1.51.51.4-1.7-1.6-1.8-1.6-1.00.61.2
Lifetime Intake3.84.79.92.3-2.3-1.92.12.1-1.7-2.4-1.6-2.4-2.6-0.03.2
Liver weight, left0.81.35.5-0.91.01.1-0.6-0.91.40.51.70.8-0.3-2.30.1
Liver weight, right2.74.87.9-2.62.22.2-2.2-2.12.12.62.32.81.8-0.5-1.8
Locomotor activity1.62.55.5-1.51.91.9-1.9-1.81.51.11.30.91.5-2.3-0.5
Locomotor testing distance0.71.73.4-1.41.61.7-1.6-1.51.00.80.80.71.5-1.9-0.3
Locomotor testing rearing0.10.30.7-0.50.60.8-0.6-0.60.50.40.40.50.2-0.50.3
Locomotion in novel chamber0.40.64.00.00.00.3-0.2-0.00.5-0.20.5-0.2-0.7-2.01.3
Locomotion in novel chamber post-restriction0.41.32.1-1.41.01.4-1.0-1.11.01.01.31.51.0-1.1-0.5
Fecal boli incidents, locomotor time 11.53.95.12.0-2.1-2.01.92.3-2.1-1.9-2.0-1.7-2.01.72.0
Change in fecal boli incidents, locomotor task0.60.63.9-0.50.80.7-0.6-0.90.70.10.5-0.10.6-2.0-0.2
Time >=10cm from walls, locomotor time 10.50.72.7-0.90.60.4-0.0-0.3-0.80.2-0.40.71.41.7-0.7
Bouts of movement, locomotor time 12.63.47.92.0-1.8-1.42.11.7-1.1-1.9-1.4-2.3-2.2-0.12.8
Total resting periods, locomotor time 12.42.87.31.8-1.6-1.11.91.4-1.0-1.7-1.4-2.1-1.80.12.7
Rest time, locomotor task time 10.81.34.91.2-0.9-0.51.20.8-0.6-1.1-1.0-1.5-1.2-0.12.2
Distance moved, locomotor task time 10.82.34.5-1.71.41.2-1.5-1.41.11.51.41.81.6-1.0-2.1
Vertical activity count, locomotor time 10.10.42.1-0.80.50.2-0.1-0.30.30.60.71.00.50.2-1.4
Time >=10cm from walls, locomotor time 20.30.95.30.1-0.5-0.41.10.8-1.2-0.1-0.90.30.12.30.8
Bouts of movement, locomotor time 20.20.51.91.0-0.9-0.50.40.6-0.2-0.5-0.3-0.7-1.1-0.21.4
Total resting periods, locomotor time 20.20.62.51.0-0.9-0.50.50.7-0.2-0.5-0.3-0.6-1.1-0.11.6
Rest time, locomotor task time 20.20.31.50.4-0.4-0.00.50.2-0.2-0.3-0.4-0.4-0.40.41.2
Distance moved, locomotor task time 20.20.31.6-0.50.40.3-0.5-0.40.50.20.70.30.1-1.3-0.8
Vertical activity count, locomotor time 20.10.10.20.1-0.4-0.40.50.4-0.4-0.2-0.00.3-0.50.5-0.1
Light reinforcement 10.10.41.20.7-0.2-0.30.30.4-0.3-0.8-0.4-0.9-0.7-0.51.1
Light reinforcement 20.20.51.30.5-0.5-0.60.50.5-1.2-1.0-1.0-1.00.00.30.5
Bone: marrow area0.10.41.10.7-0.6-0.60.30.5-0.4-0.3-0.8-0.8-0.11.0-0.1
Bone: maximum diameter0.00.10.20.3-0.3-0.30.10.20.10.2-0.0-0.00.10.3-0.5
Bone: maximum force0.00.10.60.4-0.0-0.10.0-0.10.2-0.10.2-0.2-0.4-0.80.1
Bone: maximum moment0.00.10.30.5-0.2-0.30.20.10.1-0.20.0-0.2-0.6-0.40.0
Mean time between licks in bursts0.21.11.6-1.31.11.2-1.2-1.11.11.10.90.91.2-0.6-0.5
Mean num. licks in bursts2.25.97.82.8-2.5-2.82.62.6-2.7-2.5-2.7-2.4-2.01.81.4
Cd content in liver2.02.33.6-1.81.41.4-1.2-1.41.01.81.01.91.90.9-1.8
Co content in liver1.01.21.51.1-1.2-1.11.21.1-1.1-1.2-1.0-1.1-1.10.90.8
Cu content in liver0.40.51.2-0.90.90.8-0.9-0.90.30.4-0.00.21.1-0.3-0.3
Fe content in liver1.31.63.31.4-1.2-1.21.01.2-1.5-1.4-1.8-1.5-0.70.71.3
K content in liver1.51.53.2-1.11.51.3-1.2-1.41.40.91.00.41.2-1.8-0.4
Mg content in liver0.10.10.3-0.30.50.4-0.3-0.40.20.1-0.0-0.20.5-0.50.1
Mn content in liver0.00.00.1-0.20.10.3-0.2-0.20.1-0.00.10.0-0.20.10.3
Na content in liver0.91.01.51.1-1.1-1.01.01.1-0.9-1.2-0.9-1.2-1.1-0.11.0
Rb content in liver0.20.20.7-0.10.70.5-0.5-0.60.40.3-0.2-0.20.8-0.70.2
Se content in liver0.20.31.9-0.10.10.3-0.2-0.10.0-0.50.1-0.5-0.2-1.40.8
Sr content in liver3.63.14.41.7-2.1-1.71.61.9-2.1-2.0-2.0-1.7-1.51.11.5
Zn content in liver2.63.03.9-1.92.01.9-1.9-1.91.71.61.61.31.9-1.6-1.3
Bone: minimum diameter1.01.92.7-1.41.41.5-1.4-1.41.61.51.51.41.0-1.1-1.0
Time in familiar zone, hab. session 10.40.51.5-0.70.60.7-0.6-0.60.70.50.80.60.3-1.2-0.3
Time in novel zone, hab. session 10.40.51.2-0.70.90.8-0.9-0.90.50.70.30.51.10.2-0.5
Total zone transitions, hab. session 10.20.30.60.5-0.6-0.60.80.6-0.8-0.6-0.5-0.2-0.40.30.2
Total locomotion distance, hab. session 10.71.01.40.8-1.2-0.91.21.1-1.2-1.1-0.9-0.6-1.10.51.0
Locomotion velocity, hab. session 11.21.72.51.2-1.6-1.31.61.4-1.4-1.5-1.0-1.0-1.50.51.3
Time in familiar zone, hab. session 20.30.30.70.8-0.5-0.60.60.6-0.3-0.4-0.4-0.6-0.80.20.5
Time in novel zone, hab. session 21.71.93.6-1.91.31.4-1.5-1.40.71.40.81.51.90.2-1.3
Total zone transitions, hab. session 20.60.71.20.9-0.9-1.01.10.9-1.1-0.9-1.1-0.7-0.50.60.4
Total locomotion distance, hab. session 20.60.81.50.9-0.9-0.90.90.8-1.1-1.0-1.2-1.1-0.50.30.7
Locomotion velocity, hab. session 20.81.11.71.1-1.0-1.01.00.9-1.2-1.2-1.3-1.3-0.60.10.9
Novel to familiar place preference ratio0.20.30.7-0.40.40.5-0.6-0.40.60.80.50.80.20.1-0.0
Novelty place preference0.50.61.2-0.70.80.9-0.9-0.81.01.10.91.10.3-0.3-0.2
Time in novel zone, NPP test0.50.61.1-0.70.80.8-0.8-0.70.91.10.81.00.5-0.1-0.3
Total zone transitions, NPP test0.40.61.20.6-0.6-0.90.90.7-1.0-0.8-1.1-0.90.00.7-0.0
Total locomotion distance, NPP test1.11.53.01.1-1.2-1.31.31.1-1.7-1.4-1.7-1.4-0.40.90.7
Locomotion velocity, NPP test1.42.03.31.4-1.4-1.51.51.3-1.8-1.7-1.8-1.6-0.80.71.0
Intraocular pressure1.83.04.7-2.21.61.6-1.6-1.61.52.01.62.01.80.2-2.1
Delta distance traveled before/after self-admin0.80.91.7-0.81.10.7-1.2-1.10.90.80.91.00.7-0.5-1.3
Delta ambulatory time before/after self-admin0.10.10.60.10.0-0.2-0.3-0.20.10.10.10.2-0.10.5-0.8
Parametrial fat weight20.347.861.2-7.87.67.7-7.4-7.57.16.67.16.66.3-6.0-4.7
Pavlov. Cond. lever latency0.30.40.9-0.50.50.5-0.6-0.40.70.90.80.90.2-0.4-0.6
Pavlov. Cond. magazine entry latency0.40.52.70.3-0.6-0.60.60.5-0.8-0.4-0.7-0.2-0.01.6-0.2
Pavlov. Cond. change in total contacts0.80.82.80.6-1.0-1.00.91.0-1.0-0.8-0.8-0.6-0.91.70.3
Pavlov. Cond. index score0.50.71.10.7-0.8-0.80.80.7-1.1-1.0-1.0-0.9-0.41.00.5
Pavlov. Cond. latency score0.40.61.10.6-0.6-0.70.60.6-1.0-0.9-1.0-0.9-0.21.00.4
Pavlov. Cond. lever contacts0.50.61.10.7-0.7-0.80.80.7-0.8-1.0-0.8-1.0-0.60.40.7
Pavlov. Cond. magazine entry number0.70.93.6-0.70.91.0-0.9-0.91.10.71.10.70.4-1.9-0.1
Pavlov. Cond. intertrial magazine entries1.31.62.51.3-1.1-1.41.21.3-1.6-1.5-1.5-1.4-0.70.60.8
Pavlov. Cond. lever-magazine prob. diff.0.91.11.70.9-1.0-1.11.01.0-1.3-1.2-1.2-1.1-0.61.30.5
Pavlov. Cond. response bias1.31.72.51.2-1.3-1.51.41.3-1.5-1.3-1.5-1.3-0.81.60.6
Pavlov. Cond. lever latency0.10.20.5-0.40.20.2-0.4-0.30.30.50.50.60.20.5-0.7
Pavlov. Cond. magazine entry latency0.81.11.8-1.11.21.1-1.0-1.11.01.30.71.01.3-0.2-0.9
Pavlov. Cond. change in total contacts0.30.71.1-0.81.01.0-0.9-0.90.70.80.60.71.1-0.8-0.3
Pavlov. Cond. index score0.10.10.4-0.30.50.4-0.3-0.40.40.30.10.10.5-0.6-0.0
Pavlov. Cond. latency score0.10.10.3-0.30.40.4-0.3-0.30.30.30.00.10.5-0.5-0.1
Pavlov. Cond. lever contacts0.10.10.60.10.10.20.0-0.00.0-0.2-0.2-0.30.1-0.80.5
Pavlov. Cond. magazine entry number1.11.42.51.3-1.3-1.31.21.3-1.1-1.3-0.7-1.1-1.60.51.0
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.3-0.00.1-0.00.00.10.00.40.3-0.30.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.40.60.6-0.5-0.50.40.40.20.20.7-0.6-0.2
Pavlov. Cond. response bias0.00.00.1-0.00.20.1-0.0-0.1-0.00.0-0.2-0.10.4-0.30.1
Time in closed arm before self-admin0.30.62.8-0.20.60.8-0.7-1.00.40.0-0.0-0.70.9-1.70.7
Time in closed arm after self-admin1.11.33.8-0.81.01.4-1.2-1.41.30.81.20.70.7-2.00.1
Time in open arm before self-admin0.30.41.20.0-0.4-0.61.10.8-0.4-0.4-0.10.0-0.71.0-0.3
Time in open arm after self-admin0.20.21.10.1-0.2-0.50.80.6-0.5-0.2-0.4-0.2-0.11.10.1
Bone: periosteal estimation0.00.10.50.4-0.4-0.40.20.3-0.00.1-0.2-0.2-0.20.7-0.4
Bone: periosteal perimeter0.10.10.30.5-0.4-0.30.30.4-0.1-0.3-0.2-0.4-0.3-0.40.3
Bone: post-yield work1.42.43.82.0-1.7-1.81.61.5-1.6-1.5-1.8-1.5-1.31.01.0
Progressive ratio test 1 active lever presses1.12.07.41.4-1.1-0.81.01.0-0.6-1.5-0.7-1.6-1.8-1.22.7
Progressive ratio test 1 breakpoint1.12.07.11.4-1.1-0.81.01.1-0.7-1.5-0.8-1.7-1.7-1.02.7
Progressive ratio test 1 inactive lever presses1.02.714.91.4-0.7-0.30.50.7-0.1-1.3-0.7-1.7-1.8-2.33.9
Progressive ratio test 2 active lever presses2.23.14.71.9-2.0-2.01.91.9-1.6-1.8-1.3-1.6-2.21.01.5
Progressive ratio test 2 breakpoint2.33.04.81.9-2.0-2.01.91.9-1.5-1.8-1.2-1.5-2.21.01.5
Progressive ratio test 2 inactive lever presses0.61.84.61.7-1.5-1.31.21.3-0.7-1.0-0.9-1.2-1.80.52.1
Incentive Sensitization - Responses0.61.85.81.0-1.6-1.81.61.5-1.2-0.7-0.7-0.4-1.32.4-0.4
Incentive Sensitization - Breakpoint0.71.55.00.9-1.5-1.71.51.4-1.1-0.6-0.5-0.3-1.32.2-0.5
Sum of active levers in priming session hrs 5-60.70.72.80.5-0.8-1.10.70.9-0.9-0.3-0.7-0.1-0.51.7-0.3
Progressive ratio0.41.11.9-1.11.21.0-1.0-1.11.21.40.81.01.3-0.7-0.5
Food seeking constrained by brief footshock4.45.58.72.2-2.4-2.52.72.4-2.9-2.4-2.7-2.0-1.62.61.4
Seeking ratio, punishment vs. effort1.12.43.71.6-1.7-1.71.61.7-1.9-1.8-1.6-1.3-1.31.60.5
Retroperitoneal fat weight25.0112.1142.7-11.911.711.9-11.5-11.510.810.010.59.79.9-9.7-6.7
Reaction time number correct0.10.41.1-0.70.50.5-0.3-0.5-0.20.4-0.00.71.01.0-0.7
Reaction time mean minus median0.21.42.7-1.61.11.1-1.1-1.10.51.20.81.41.60.5-1.4
Reaction time mean minus median AUC0.31.82.8-1.71.41.3-1.3-1.30.91.41.11.61.60.1-1.5
Reaction time num false alarms0.61.11.9-0.91.21.1-1.4-1.21.00.90.70.61.3-1.2-0.6
Reaction time num false alarms AUC0.41.01.6-1.01.11.1-1.2-1.10.90.80.70.61.3-1.1-0.7
Reaction time trials correct on left0.10.41.1-0.70.50.5-0.3-0.5-0.20.4-0.00.71.01.0-0.7
Reaction time trials on left0.10.41.2-0.80.50.5-0.4-0.5-0.10.50.10.81.11.0-0.7
Reaction time mean0.10.20.8-0.60.10.3-0.3-0.1-0.20.40.10.60.40.9-0.4
Reaction time mean AUC0.10.21.1-0.60.10.2-0.2-0.1-0.10.50.20.70.31.1-0.5
Median of all reaction times0.10.21.4-0.1-0.4-0.20.20.4-0.6-0.0-0.30.2-0.11.20.0
Reaction time omissions0.40.71.1-1.00.80.8-0.7-0.80.61.00.71.01.00.3-1.0
Reaction time false alarm rate0.40.62.3-0.50.70.7-0.9-0.70.90.50.70.20.5-1.5-0.3
Reaction time premature initiation rate0.40.71.50.7-0.4-0.40.60.4-0.9-1.2-1.0-1.1-0.2-1.01.2
Reaction time premature initiations0.10.30.80.3-0.1-0.10.40.1-0.9-0.8-0.9-0.60.3-0.10.7
Std. dev. reaction times0.31.02.0-1.40.80.8-0.7-0.80.21.10.61.41.31.1-1.3
Reaction time trials completed0.10.41.2-0.80.50.5-0.4-0.5-0.10.50.10.81.11.0-0.7
Reaction time trials AUC0.10.51.2-0.90.50.6-0.4-0.6-0.10.50.10.81.10.9-0.8
Run reversals in cocaine runway, females0.60.71.41.2-0.9-1.01.00.8-0.8-0.7-0.9-0.7-0.80.70.4
Run reversals in cocaine runway, males0.10.10.60.4-0.3-0.30.50.20.1-0.10.30.1-0.80.2-0.3
Latency to leave start box in cocaine runway1.01.45.10.9-0.9-1.11.20.9-1.5-0.6-1.8-0.90.32.2-0.2
Latency to leave start box in cocaine runway, F0.50.62.20.8-0.7-0.91.00.7-0.7-0.1-0.9-0.40.01.5-0.5
Latency to leave start box in cocaine runway, M1.00.93.50.3-0.6-0.60.50.5-1.5-0.7-1.6-0.70.51.90.0
Std. dev. time between licks in bursts0.00.10.2-0.20.30.4-0.4-0.30.20.30.10.30.3-0.10.4
Total sessions with >9 infusions4.05.015.82.2-2.1-1.72.32.1-1.5-2.2-1.4-2.3-2.8-0.24.0
Short access day 1 total inactive lever presses1.73.311.22.0-1.9-1.31.41.7-1.1-1.6-1.4-1.8-2.3-0.23.3
Short access day 10 total inactive lever presses0.00.20.50.1-0.3-0.1-0.10.2-0.40.2-0.70.10.40.70.7
Short access day 1 total infusions1.32.610.71.6-1.4-1.01.31.3-0.9-1.5-1.1-2.0-1.7-0.53.3
Short access day 10 total infusions2.44.07.22.1-2.2-1.92.12.1-1.7-2.2-1.6-2.1-2.30.42.7
Short access total infusions2.23.210.41.8-1.7-1.31.51.6-1.1-1.8-1.1-2.0-2.2-0.63.2
Short access day 1 locomotion1.32.28.21.4-1.3-1.01.31.3-0.7-1.4-0.8-1.7-1.8-0.62.9
Short access day 10 total locomotion0.31.44.80.9-1.2-0.60.91.1-1.2-1.4-1.1-1.2-1.20.42.2
Short access total locomotion2.43.614.61.6-1.8-1.11.71.7-1.3-1.8-1.1-1.7-2.4-0.13.8
One hour access (0.3 mA shock)3.94.76.32.4-2.5-2.42.12.2-2.3-2.1-2.2-2.3-1.81.81.6
Compulsive drug intake0.30.40.9-0.70.50.6-0.6-0.40.51.00.40.80.60.4-0.6
One hour access (shock baseline)1.95.16.42.5-2.5-2.52.32.3-2.2-2.5-2.0-2.4-2.31.12.0
Social response proportion0.20.20.70.4-0.3-0.10.10.20.0-0.4-0.1-0.7-0.6-0.70.8
Social responses0.30.40.9-0.50.60.7-0.7-0.80.90.90.70.50.6-0.2-0.4
Social time0.71.22.91.0-0.8-0.71.00.8-0.9-1.6-0.7-1.4-1.2-0.51.7
Soleus weight3.710.914.33.6-3.3-3.83.73.4-3.7-3.5-3.6-3.3-2.82.61.9
Bone: stiffness0.61.11.9-0.81.01.0-1.1-1.11.31.01.21.00.6-1.4-0.8
Tibialis anterior weight1.34.46.22.2-2.2-2.52.42.2-2.3-2.2-2.1-2.1-1.91.81.1
Time to tail flick, vehicle, before self-admin0.10.10.4-0.3-0.3-0.00.20.3-0.0-0.30.2-0.1-0.6-0.60.6
Time to tail flick, vehicle, after self-admin1.02.14.2-1.61.51.7-2.1-1.51.31.11.10.91.5-1.8-0.6
Time to tail flick, test, before self-admin1.82.03.01.7-1.3-1.61.31.4-1.4-1.7-1.1-1.6-1.60.11.5
Time to tail flick, test, after self-admin2.62.83.71.5-1.8-1.51.71.8-1.9-1.9-1.7-1.8-1.50.91.7
Delta time to tail flick, vehicle, before/after SA0.40.51.4-0.50.80.7-1.1-0.70.40.60.20.41.2-0.4-0.5
Delta time to tail flick, test, before/after SA1.41.72.71.1-1.5-0.91.41.3-1.4-1.3-1.6-1.4-1.01.11.6
Tibia length1.95.26.7-2.22.52.5-2.1-2.42.62.32.62.21.7-2.6-1.4
Ambulatory time before self-admin0.00.10.4-0.30.30.30.0-0.40.10.30.30.30.60.4-0.7
Ambulatory time after self-admin0.61.05.5-0.70.60.4-0.6-0.80.70.90.81.10.60.7-2.3
Bone: tissue strength0.30.31.00.6-0.2-0.30.40.30.0-0.70.0-0.8-1.0-0.80.5
Total heroin consumption5.05.912.22.3-2.9-2.72.82.7-2.4-1.8-2.0-1.4-2.33.51.4
Bone: trabecular number2.13.97.11.9-1.9-2.11.71.9-2.7-1.9-2.6-1.8-0.92.40.9
Bone: trabecular spacing1.11.64.2-1.11.01.2-0.9-0.92.01.42.01.5-0.2-1.1-0.5
Bone: trabecular thickness0.91.33.50.7-0.9-1.00.80.8-1.9-1.4-1.8-1.20.21.40.4
Bone: trabecular tissue density0.10.20.6-0.40.40.3-0.2-0.3-0.2-0.2-0.3-0.30.8-0.7-0.3
Water consumed over 24 hours0.10.20.4-0.40.40.4-0.3-0.40.30.60.00.50.60.4-0.4
Number of responses in last shaping day0.81.14.31.0-1.1-0.60.80.9-0.8-0.8-1.0-0.9-0.90.52.1