Hub : Genes

LOC120100677

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr2_30467590_30469768 0.03 0.02 8.2e-05 0.03 0.01 0.03 0.03 2.2e-05 1.8e-03 1.6e-05 2.3e-05
2 Liver gene expression LOC120100677 0.25 0.09 0.0e+00 0.16 0.18 0.18 0.18 4.2e-17 4.0e-20 6.1e-20 4.3e-20
3 PL intron excision ratio chr2_30467590_30478990 0.02 0.01 4.1e-03 0.03 0.02 0.02 0.02 2.5e-04 5.7e-03 2.8e-03 1.7e-03
4 NAcc intron excision ratio chr2_30467590_30478990 0.08 0.04 1.2e-12 0.08 0.06 0.07 0.07 1.0e-11 6.5e-10 3.7e-11 5.1e-11
5 NAcc gene expression LOC120100677 0.2 0.07 0.0e+00 0.32 0.26 0.31 0.31 3.2e-49 2.0e-39 2.1e-47 4.1e-48
6 pVTA gene expression LOC120100677 0.11 0.07 5.9e-07 0.04 0.06 0.07 0.09 3.4e-04 9.8e-06 4.8e-06 2.0e-07
7 Brain gene expression LOC120100677 0.22 0.11 5.8e-15 0.15 0.14 0.16 0.16 1.2e-13 1.2e-12 2.0e-14 1.7e-14
8 BLA gene expression LOC120100677 0.11 0.07 4.4e-03 0 0.02 0 0.01 2.8e-01 2.1e-02 2.2e-01 7.2e-02
9 IL gene expression LOC120100677 0.28 0.13 2.3e-03 0.13 0.08 0.06 0.18 4.2e-04 5.6e-03 1.3e-02 3.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.10.30.5-0.3-0.4-0.3-0.1-0.1-0.10.00.3
Area under the delay curve0.50.82.4-1.20.91.50.9-1.00.50.80.50.1
BMI with tail1.03.55.8-2.42.42.32.0-1.91.81.60.2-0.9
BMI without tail0.73.76.5-2.51.91.82.1-2.32.41.91.0-0.2
Body weight2.08.913.1-3.62.93.33.0-3.23.33.22.31.2
Weight adjusted by age0.71.99.10.20.2-0.2-0.40.7-0.6-1.2-2.4-3.0
Bone surface0.10.20.5-0.20.70.60.2-0.70.30.40.10.0
Bone volume0.10.20.50.7-0.4-0.6-0.4-0.0-0.4-0.2-0.20.3
Breakpoint value in progressive ratio session0.00.10.20.1-0.20.3-0.20.2-0.5-0.10.10.3
Number of licking bursts0.20.51.6-0.8-1.0-0.30.00.21.1-0.01.30.6
Context. condit. distance diff. score1.01.21.80.9-1.2-1.4-1.21.3-0.8-1.2-0.8-0.5
Locomotion velocity, session 10.60.61.7-0.0-1.2-1.0-0.30.10.5-0.21.11.3
Locomotion distance, session 10.60.82.20.4-1.5-1.1-0.70.8-0.2-0.60.81.1
Locomotion velocity, session 20.81.03.2-0.2-0.7-1.00.4-0.61.10.71.31.8
Locomotion distance, session 21.21.75.70.7-2.4-1.7-1.21.0-0.3-1.10.91.1
Locomotion velocity, session 30.30.41.1-0.5-1.0-0.6-0.40.60.0-0.90.4-0.3
Locomotion distance, session 30.30.31.00.0-0.7-0.5-0.50.8-0.4-1.00.1-0.5
Stereotopy head waving bouts, day 30.70.81.70.5-1.3-0.4-1.00.9-0.7-0.70.91.2
Stereotopy head waving duration, day 30.30.41.5-0.10.40.80.1-0.30.00.70.81.2
Locomotion velocity, session 70.80.91.80.6-0.7-1.3-0.80.8-0.5-1.1-1.3-1.2
Locomotion distance, session 70.10.10.4-0.3-0.2-0.50.3-0.40.60.20.20.1
Stereotopy head waving bouts, day 71.01.22.80.2-1.3-0.8-1.41.7-0.6-1.6-0.3-0.5
Stereotopy head waving duration, day 70.20.20.7-0.0-0.3-0.1-0.70.9-0.2-0.7-0.4-0.4
Locomotion velocity, session 82.32.87.31.5-2.5-2.7-1.71.6-0.8-1.4-0.60.9
Locomotion distance, session 80.81.23.10.4-1.8-1.8-1.11.2-0.3-1.3-0.4-0.3
Degree of sensitization distance0.20.30.70.2-0.2-0.40.2-0.60.60.70.20.9
Degree of sensitization stereotypy1.11.22.70.2-0.8-0.7-1.21.4-0.6-1.6-1.0-1.5
Conditioned locomotion0.30.30.80.10.60.6-0.30.3-0.9-0.4-0.7-0.5
Cocaine response after cond. corrected0.40.61.3-0.90.50.40.9-1.01.20.70.4-0.2
Cocaine response after cond. not corrected0.50.82.2-1.00.50.31.0-1.21.51.00.5-0.0
Cocaine response before conditioning0.10.10.30.2-0.5-0.5-0.20.2-0.0-0.3-0.2-0.3
Saline control response0.30.51.2-0.31.10.50.6-0.40.30.4-1.1-0.9
Bone: connectivity density0.10.10.6-0.30.50.70.1-0.20.10.20.40.0
Bone: cortical apparent density2.23.45.91.5-1.6-1.8-2.12.1-1.8-2.4-1.6-1.5
Bone: cortical area2.43.910.22.60.3-0.6-1.81.3-2.8-1.4-3.2-1.8
Bone: cortical porosity0.10.10.2-0.4-0.30.3-0.10.10.1-0.10.40.4
Bone: cortical porosity0.30.30.60.3-0.8-0.3-0.70.7-0.5-0.7-0.20.2
Bone: cortical thickness3.96.613.92.8-0.5-1.3-2.72.3-3.3-2.5-3.7-2.3
Bone: cortical thickness0.50.62.80.31.0-0.00.2-0.4-0.40.0-1.7-1.2
Bone: cortical tissue density1.93.05.31.4-1.6-1.7-2.02.0-1.7-2.3-1.3-1.3
Condit. Reinf. active minus inactive responses0.40.42.2-0.40.1-0.6-0.20.10.4-0.5-1.0-1.5
Condit. Reinf. active-inactive response ratio0.90.94.6-0.00.6-0.3-0.40.2-0.2-0.7-1.7-2.2
Condit. Reinf. active responses0.20.30.9-0.80.1-0.70.2-0.21.0-0.1-0.3-0.9
Condit. Reinf. inactive responses0.40.51.2-0.7-0.0-0.20.7-0.61.10.70.70.7
Incentive salience index mean0.40.51.8-1.20.5-0.10.7-0.71.30.40.2-0.5
Condit. Reinf. lever presses0.50.71.9-1.00.10.10.7-0.71.40.61.30.7
Condit. Reinf. active minus inactive responses0.71.13.20.6-0.8-1.3-0.50.5-0.3-1.0-1.5-1.8
Condit. Reinf. active-inactive response ratio0.10.10.3-0.0-0.5-0.4-0.10.00.2-0.2-0.4-0.5
Condit. Reinf. active responses1.01.43.60.7-0.9-1.4-0.80.8-0.5-1.3-1.6-1.9
Condit. Reinf. inactive responses0.20.21.1-0.40.50.00.3-0.30.3-0.0-0.6-1.1
Condit. Reinf. lever presses0.30.51.10.5-0.8-1.1-0.30.4-0.2-0.6-0.9-0.9
Condit. Reinf. lever reinforcers received0.81.13.10.5-0.8-1.2-0.70.7-0.4-1.1-1.5-1.8
Conditioned reinforcement - actives0.20.72.0-0.61.41.40.8-0.70.20.8-0.5-0.1
Conditioned reinforcement - inactives0.10.30.70.8-0.1-0.4-0.60.4-0.7-0.5-0.8-0.2
Conditioned locomotion0.40.51.50.50.20.5-0.70.7-1.1-0.7-1.2-0.3
Patch foraging indifference point 0 sec0.82.33.8-1.61.61.02.0-1.72.01.80.90.2
Patch foraging indifference point AUC0.40.91.7-1.00.31.20.9-0.80.61.01.31.0
Delay disc. indifference point, 0s delay0.60.71.70.7-0.7-1.3-0.50.4-0.3-0.8-0.9-1.1
Delay disc. indifference point, 16s delay0.40.53.2-0.70.81.80.3-0.4-0.40.3-0.1-0.1
Delay disc. indifference point, 2s delay0.10.10.3-0.60.10.40.1-0.10.4-0.1-0.4-0.5
Delay disc. indifference point, 24s delay2.13.34.7-2.11.51.72.1-2.12.21.81.70.6
Delay disc. indifference point, 4s delay0.40.41.6-0.2-0.3-0.40.6-0.70.70.61.20.7
Delay disc. indifference point, 8s delay1.32.14.3-1.91.52.11.6-1.61.21.40.80.4
Indifference point function ln k0.00.10.50.20.3-0.2-0.0-0.0-0.1-0.2-0.7-0.4
Indifference point function log k0.00.10.50.20.3-0.2-0.0-0.0-0.1-0.2-0.7-0.4
Patch foraging total patch changes 0 sec0.82.54.1-1.71.61.12.0-1.72.01.91.10.2
Patch foraging total patch changes 12 sec1.21.52.4-1.61.11.31.4-1.31.41.40.90.0
Patch foraging total patch changes 18 sec0.10.30.7-0.90.50.50.8-0.50.70.60.1-0.3
Patch foraging total patch changes 24 sec0.41.52.6-1.41.41.61.4-1.31.01.20.3-0.6
Patch foraging total patch changes 6 sec2.03.35.3-2.01.51.42.1-1.92.32.11.80.6
Patch foraging time to switch 0 sec0.10.31.30.30.1-0.5-0.50.2-0.2-0.5-1.2-0.8
Patch foraging water rate 0 sec0.10.61.5-0.60.50.60.8-0.40.60.81.20.9
Patch foraging water rate 12 sec0.31.32.40.5-0.7-0.7-1.31.3-1.0-1.5-1.5-1.1
Patch foraging water rate 18 sec0.10.21.1-0.40.40.5-0.0-0.1-0.1-0.2-0.7-1.1
Patch foraging water rate 24 sec0.81.21.8-1.31.21.31.3-1.21.11.10.40.2
Patch foraging water rate 6 sec0.60.91.71.2-1.0-0.8-0.91.3-1.1-0.8-0.10.9
Seeking ratio, delayed vs. immediate footshock0.40.51.3-1.10.10.30.6-0.61.20.41.00.6
Distance traveled before self-admin0.10.30.9-0.90.11.00.1-0.10.20.20.70.1
Distance traveled after self-admin1.42.54.1-2.01.11.31.8-1.81.91.71.40.4
Extensor digitorum longus weight0.10.20.4-0.20.40.60.1-0.40.40.50.60.7
Bone: elastic displacement1.31.73.61.2-1.9-0.6-1.61.6-1.5-1.20.41.0
Bone: elastic work0.60.71.31.0-0.9-0.0-1.10.8-1.1-0.40.41.1
Bone: endosteal estimation0.30.71.8-0.50.90.51.0-1.30.81.20.30.2
Bone: endosteal perimeter0.10.30.60.30.80.10.4-0.6-0.10.4-0.7-0.7
Epididymis fat weight0.94.59.5-3.12.12.32.1-2.22.82.00.9-0.3
Delta time in closed arm before/after self-admin1.11.02.80.7-0.90.1-1.21.3-1.7-1.2-0.5-0.3
Delta time in open arm before/after self-admin0.70.83.50.00.7-0.70.0-0.10.4-0.3-1.7-1.9
Diff in mean of infusions in LGA sessions0.30.62.01.1-0.5-0.1-0.90.8-1.4-0.5-0.10.5
Delay discount exponential model param0.71.02.51.3-0.9-1.6-1.01.1-0.7-0.9-0.7-0.2
Extinction: sum of active levers before priming0.10.20.6-0.4-0.10.1-0.10.20.3-0.4-0.5-0.8
Active lever presses in extinction session 60.40.42.3-0.80.61.50.2-0.3-0.40.10.60.3
Bone: final force0.61.02.91.50.1-0.7-0.90.5-1.1-0.5-1.7-0.9
Bone: final moment0.50.72.21.30.2-0.5-0.90.4-0.9-0.3-1.5-0.8
Food consumed during 24 hour testing period0.71.49.1-0.90.5-0.10.2-0.40.6-0.4-1.4-3.0
Glucose2.23.56.42.1-1.9-2.5-1.81.9-1.5-2.0-1.7-1.0
Heart weight1.11.84.5-2.11.51.71.1-1.21.61.0-0.1-0.3
Delay discount hyperbolic model param0.60.81.81.2-0.8-1.3-0.91.0-0.7-0.8-0.7-0.2
Intermittent access intake day 1-15 change0.20.81.41.1-0.8-1.2-1.11.0-0.7-0.9-0.80.1
Intermittent access intake escalation0.21.01.81.3-0.8-1.3-1.21.1-0.7-1.0-0.90.1
Intermittent access intake escalation 20.40.61.51.2-0.3-0.6-0.90.8-1.0-0.7-0.9-0.1
Intermitt. access day 1 inactive lever presses0.33.75.82.3-1.5-1.6-2.32.2-2.4-2.1-1.5-0.4
Intermitt. access day 15 inactive lever presses0.63.14.91.5-2.2-2.2-2.22.2-1.4-2.1-0.1-0.2
Intermitt. access escalation Index0.30.82.51.2-1.3-1.6-0.60.6-0.6-0.70.60.0
Intermittent access day 1 total infusions0.92.66.4-2.51.72.31.3-1.31.61.30.90.1
Intermittent access day 15 total infusions0.10.20.5-0.50.4-0.0-0.20.10.5-0.2-0.7-0.4
Intermittent access terminal intake (last 3 days)0.10.20.4-0.60.30.4-0.40.30.2-0.3-0.7-0.2
Intermittent access total infusions0.40.51.8-1.30.90.90.4-0.40.80.3-0.3-0.3
Intermittent access day 1 locomotion0.51.03.5-1.51.21.90.6-0.60.60.8-0.20.3
Intermittent access day 15 total locomotion0.41.54.5-1.61.72.10.5-0.60.80.8-1.1-0.4
Intermittent access total locomotion0.50.62.7-1.20.81.6-0.00.00.20.2-0.70.0
Intermittent access standard deviation0.10.30.7-0.6-0.20.4-0.70.7-0.1-0.8-0.5-0.6
Left kidney weight2.721.836.0-6.05.15.45.0-5.15.14.82.30.7
Right kidney weight2.920.033.0-5.75.15.24.9-4.84.84.61.80.1
Cocaine induced anxiety0.10.20.9-0.20.61.00.2-0.1-0.40.0-0.1-0.2
Post-drug Anxiety0.70.83.0-1.21.11.70.7-0.70.20.50.1-0.2
Baseline Anxiety0.20.41.5-1.2-0.10.30.2-0.41.00.30.60.7
Tail length0.95.17.9-2.31.51.52.4-2.72.82.72.21.8
Length with tail1.88.011.6-2.82.42.62.9-3.03.13.42.72.5
Length without tail0.73.75.4-1.92.02.02.1-2.02.02.31.41.4
Times rat made contact with spout1.51.75.4-1.81.21.01.1-1.11.20.3-0.7-2.3
Lifetime Intake0.60.72.7-1.60.81.20.5-0.50.90.40.20.2
Liver weight, left2.44.16.6-2.42.41.72.4-2.62.32.0-0.0-0.7
Liver weight, right2.23.85.4-2.32.21.92.2-2.32.22.01.10.8
Locomotor activity0.20.31.2-0.7-0.0-0.10.00.30.6-0.5-0.4-1.1
Locomotor testing distance0.71.66.8-1.11.40.70.9-0.70.70.0-1.5-2.6
Locomotor testing rearing0.51.87.7-0.71.60.80.8-0.50.2-0.2-2.0-2.8
Locomotion in novel chamber0.40.51.1-0.2-0.70.0-0.80.8-0.6-1.1-0.7-0.8
Locomotion in novel chamber post-restriction0.61.97.0-0.8-0.50.10.7-1.01.31.02.72.3
Fecal boli incidents, locomotor time 10.10.20.70.2-0.10.4-0.50.4-0.30.10.80.8
Change in fecal boli incidents, locomotor task0.10.10.6-0.1-0.5-0.30.1-0.10.2-0.10.30.8
Time >=10cm from walls, locomotor time 10.70.92.10.9-0.80.6-1.00.9-1.3-0.51.01.4
Bouts of movement, locomotor time 10.30.40.90.60.7-0.90.3-0.40.20.4-0.9-0.5
Total resting periods, locomotor time 10.30.30.60.60.8-0.80.5-0.60.40.6-0.6-0.2
Rest time, locomotor task time 10.30.41.5-0.0-1.1-1.2-0.60.50.3-0.40.20.6
Distance moved, locomotor task time 10.30.81.9-0.51.41.10.9-0.80.00.4-0.7-1.2
Vertical activity count, locomotor time 10.10.92.40.11.50.80.7-0.7-0.70.2-1.2-1.3
Time >=10cm from walls, locomotor time 20.10.41.3-0.7-0.10.80.4-0.40.40.41.10.4
Bouts of movement, locomotor time 20.00.10.7-0.2-0.30.1-0.0-0.1-0.0-0.00.80.1
Total resting periods, locomotor time 20.00.10.4-0.1-0.6-0.2-0.30.2-0.0-0.20.70.0
Rest time, locomotor task time 21.22.13.11.0-1.2-1.4-1.71.5-1.0-1.8-1.7-1.6
Distance moved, locomotor task time 20.81.11.9-1.31.41.21.4-1.20.50.8-0.3-0.8
Vertical activity count, locomotor time 20.30.61.1-1.01.10.60.9-0.90.30.3-0.7-0.8
Light reinforcement 10.41.93.2-1.31.61.51.8-1.61.21.50.4-0.4
Light reinforcement 20.30.62.5-0.90.51.60.2-0.40.10.41.10.5
Bone: marrow area0.30.71.7-0.50.90.51.0-1.30.91.20.40.3
Bone: maximum diameter0.40.92.40.51.50.80.2-0.5-0.80.5-1.4-1.1
Bone: maximum force0.40.83.21.10.4-0.4-0.60.1-0.8-0.3-1.8-1.1
Bone: maximum moment0.30.62.41.00.5-0.2-0.50.0-0.7-0.1-1.6-0.9
Mean time between licks in bursts0.10.30.80.10.60.70.4-0.80.20.90.20.5
Mean num. licks in bursts0.61.65.7-0.01.70.80.5-0.7-0.5-0.0-2.1-2.4
Cd content in liver0.80.93.50.60.2-0.5-0.30.6-0.8-0.7-1.9-1.7
Co content in liver0.50.61.4-0.60.90.20.7-0.90.50.3-1.1-1.2
Cu content in liver0.00.10.10.1-0.30.0-0.30.3-0.3-0.3-0.00.2
Fe content in liver0.81.02.01.4-1.0-1.3-1.10.8-1.0-0.7-0.60.6
K content in liver1.11.01.8-1.11.20.91.3-1.31.11.1-0.10.0
Mg content in liver0.80.81.50.9-0.6-0.7-1.00.9-1.0-1.0-1.2-0.6
Mn content in liver2.32.63.71.9-1.5-1.9-1.71.7-1.8-1.7-1.3-0.3
Na content in liver0.91.01.8-0.91.41.01.1-1.11.01.20.20.5
Rb content in liver0.30.31.50.20.40.1-0.20.1-0.5-0.3-1.2-0.9
Se content in liver1.11.32.81.2-1.0-1.7-1.21.3-1.0-1.3-0.8-0.2
Sr content in liver0.30.20.50.10.6-0.30.7-0.50.40.7-0.30.5
Zn content in liver0.10.10.2-0.40.20.4-0.10.20.1-0.2-0.40.0
Bone: minimum diameter2.85.49.73.1-1.2-2.0-2.52.1-2.8-2.2-2.8-1.5
Time in familiar zone, hab. session 10.20.20.6-0.5-0.50.5-0.10.20.1-0.20.70.3
Time in novel zone, hab. session 11.11.22.8-0.51.70.41.3-1.41.01.2-0.5-1.1
Total zone transitions, hab. session 10.50.61.70.2-1.3-1.1-0.50.50.0-0.41.01.1
Total locomotion distance, hab. session 10.60.82.10.8-1.2-0.9-0.60.6-0.4-0.21.11.5
Locomotion velocity, hab. session 10.81.22.91.1-1.4-1.0-0.91.0-0.8-0.50.81.7
Time in familiar zone, hab. session 21.01.13.0-1.31.41.71.0-1.00.70.8-0.1-0.8
Time in novel zone, hab. session 20.10.10.60.1-0.3-0.8-0.1-0.10.3-0.0-0.00.2
Total zone transitions, hab. session 20.81.02.9-1.1-0.6-0.10.6-0.61.40.61.71.4
Total locomotion distance, hab. session 20.20.20.90.0-0.9-0.6-0.40.50.0-0.40.40.5
Locomotion velocity, hab. session 20.20.31.0-0.1-1.0-0.6-0.30.30.2-0.30.70.7
Novel to familiar place preference ratio0.40.51.20.5-0.1-0.2-0.50.7-0.9-0.8-0.7-1.1
Novelty place preference0.40.51.80.50.2-0.2-0.40.5-0.8-0.8-1.0-1.3
Time in novel zone, NPP test0.50.61.90.60.2-0.2-0.50.6-0.9-0.8-1.1-1.4
Total zone transitions, NPP test0.91.33.5-0.1-1.8-1.1-0.40.30.6-0.21.91.7
Total locomotion distance, NPP test1.42.05.41.1-2.3-1.6-1.61.5-0.8-1.30.71.2
Locomotion velocity, NPP test1.31.95.31.0-2.3-1.6-1.51.4-0.6-1.20.81.2
Intraocular pressure2.13.46.01.6-2.2-2.2-1.82.1-1.9-2.5-0.4-0.7
Delta distance traveled before/after self-admin1.41.52.8-1.11.20.51.7-1.61.61.60.60.3
Delta ambulatory time before/after self-admin0.91.53.0-1.21.10.31.7-1.61.71.50.20.0
Parametrial fat weight0.10.20.4-0.50.50.40.4-0.40.60.3-0.1-0.0
Pavlov. Cond. lever latency0.50.61.30.9-0.2-0.7-0.60.7-0.8-0.7-1.1-1.1
Pavlov. Cond. magazine entry latency3.44.46.4-2.01.91.82.5-2.52.42.51.71.1
Pavlov. Cond. change in total contacts0.70.81.5-0.61.20.71.2-1.20.71.10.10.2
Pavlov. Cond. index score1.92.43.3-1.61.41.51.8-1.81.61.81.30.9
Pavlov. Cond. latency score1.51.92.5-1.41.21.51.5-1.61.41.61.31.0
Pavlov. Cond. lever contacts0.20.20.8-0.30.10.30.4-0.30.30.40.60.9
Pavlov. Cond. magazine entry number5.46.810.72.7-2.8-2.4-3.33.2-2.9-3.0-1.4-0.5
Pavlov. Cond. intertrial magazine entries0.60.71.40.9-0.9-1.2-1.01.0-0.8-0.9-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.1.72.12.9-1.41.21.31.7-1.71.61.71.41.0
Pavlov. Cond. response bias3.13.95.9-2.01.91.72.4-2.42.32.31.30.8
Pavlov. Cond. lever latency0.20.31.3-0.30.10.9-0.10.0-0.20.30.81.2
Pavlov. Cond. magazine entry latency1.62.33.7-1.41.91.11.8-1.91.61.4-0.8-1.4
Pavlov. Cond. change in total contacts0.10.30.90.5-0.2-0.8-0.10.1-0.0-0.3-1.0-0.9
Pavlov. Cond. index score0.50.82.5-0.40.9-0.10.9-0.90.80.4-1.1-1.6
Pavlov. Cond. latency score0.71.12.9-0.71.10.21.1-1.11.00.6-1.0-1.7
Pavlov. Cond. lever contacts0.40.61.90.4-0.3-1.1-0.10.20.0-0.6-1.1-1.4
Pavlov. Cond. magazine entry number1.21.53.30.8-1.6-0.8-1.21.3-0.9-0.91.21.8
Pavlov. Cond. intertrial magazine entries0.30.60.90.9-0.9-0.4-0.71.0-0.9-0.50.60.9
Pavlov. Cond. lever-magazine prob. diff.0.60.93.1-0.50.9-0.10.8-0.90.80.4-1.3-1.7
Pavlov. Cond. response bias0.40.52.00.30.3-0.60.2-0.10.1-0.2-1.3-1.4
Time in closed arm before self-admin0.50.82.41.3-1.1-1.6-0.70.7-0.3-0.40.20.8
Time in closed arm after self-admin1.11.22.41.2-1.6-1.0-1.21.3-1.2-1.00.20.6
Time in open arm before self-admin2.32.85.4-2.31.52.31.7-1.71.51.71.10.5
Time in open arm after self-admin2.32.55.2-2.01.70.91.9-1.92.31.4-0.1-0.9
Bone: periosteal estimation0.41.03.41.40.6-0.1-0.60.2-1.3-0.3-1.8-1.0
Bone: periosteal perimeter0.61.33.81.60.70.1-0.60.3-1.7-0.3-1.9-1.0
Bone: post-yield work0.20.40.9-0.20.70.40.7-0.90.40.90.20.6
Progressive ratio test 1 active lever presses0.20.31.0-1.00.40.60.3-0.20.60.30.40.5
Progressive ratio test 1 breakpoint0.10.20.8-0.90.30.50.2-0.10.40.20.30.5
Progressive ratio test 1 inactive lever presses0.10.31.2-0.70.10.30.1-0.10.20.20.91.1
Progressive ratio test 2 active lever presses0.81.22.6-1.61.51.20.9-1.01.30.9-0.6-0.1
Progressive ratio test 2 breakpoint0.81.02.4-1.51.31.00.8-0.91.30.8-0.5-0.1
Progressive ratio test 2 inactive lever presses0.20.51.4-0.91.20.80.5-0.60.70.6-0.4-0.1
Incentive Sensitization - Responses0.61.83.5-1.31.90.71.5-1.61.71.4-0.4-0.7
Incentive Sensitization - Breakpoint0.71.73.1-1.31.70.71.4-1.61.81.3-0.3-0.6
Sum of active levers in priming session hrs 5-60.20.20.3-0.40.00.40.2-0.40.50.40.50.6
Progressive ratio0.10.40.9-0.00.5-1.00.5-0.40.80.3-0.7-0.8
Food seeking constrained by brief footshock1.21.52.5-1.60.60.71.4-1.31.61.51.00.9
Seeking ratio, punishment vs. effort0.30.72.0-0.8-0.21.30.5-0.50.20.61.41.1
Retroperitoneal fat weight0.31.23.2-1.70.80.71.0-1.21.80.80.0-0.5
Reaction time number correct0.31.01.80.8-0.9-1.2-1.11.0-0.8-1.3-1.1-0.6
Reaction time mean minus median0.10.62.10.4-1.5-1.0-0.70.9-0.0-0.60.5-0.1
Reaction time mean minus median AUC0.00.20.80.0-0.9-0.4-0.30.50.2-0.30.4-0.3
Reaction time num false alarms0.10.20.6-0.30.80.70.4-0.40.10.5-0.2-0.4
Reaction time num false alarms AUC0.20.41.4-0.61.01.20.6-0.50.30.70.1-0.1
Reaction time trials correct on left0.31.01.80.8-0.9-1.2-1.11.0-0.8-1.3-1.1-0.6
Reaction time trials on left0.41.32.30.9-1.1-1.4-1.31.2-1.0-1.5-1.2-0.7
Reaction time mean1.63.65.01.8-2.0-2.2-1.92.1-1.5-2.1-1.7-1.7
Reaction time mean AUC1.12.73.81.5-1.8-1.9-1.71.9-1.2-1.8-1.3-1.3
Median of all reaction times2.13.34.01.8-1.5-2.0-1.81.9-1.6-2.0-2.0-1.8
Reaction time omissions2.84.67.51.4-2.2-2.0-2.32.2-1.8-2.7-1.9-2.5
Reaction time false alarm rate0.91.32.8-1.01.31.71.2-1.10.81.40.80.4
Reaction time premature initiation rate2.64.05.9-2.21.72.02.3-2.02.32.41.80.7
Reaction time premature initiations0.41.12.1-1.30.80.91.2-1.01.41.20.90.1
Std. dev. reaction times0.61.94.71.0-2.2-1.8-1.51.7-0.7-1.5-0.2-0.7
Reaction time trials completed0.41.32.30.9-1.1-1.4-1.31.2-1.0-1.5-1.2-0.7
Reaction time trials AUC0.41.52.41.0-0.9-1.4-1.31.2-1.1-1.6-1.5-1.0
Run reversals in cocaine runway, females0.40.51.0-0.5-1.00.8-0.70.7-0.3-0.30.61.0
Run reversals in cocaine runway, males0.40.41.00.4-0.90.0-0.70.5-0.4-0.41.00.9
Latency to leave start box in cocaine runway0.60.82.40.8-0.8-0.9-0.30.3-0.20.11.61.6
Latency to leave start box in cocaine runway, F0.30.41.60.60.3-0.50.3-0.10.00.70.91.3
Latency to leave start box in cocaine runway, M0.60.51.80.4-1.3-0.4-0.70.7-0.4-0.60.90.7
Std. dev. time between licks in bursts0.91.72.6-1.21.11.41.2-1.51.31.61.21.1
Total sessions with >9 infusions0.40.52.3-1.50.30.80.4-0.40.80.40.70.6
Short access day 1 total inactive lever presses0.20.31.2-1.10.30.50.2-0.30.80.30.20.8
Short access day 10 total inactive lever presses0.10.72.21.3-0.6-1.5-0.60.6-0.4-0.4-0.01.0
Short access day 1 total infusions0.20.41.5-0.9-0.00.40.2-0.10.60.21.21.0
Short access day 10 total infusions0.20.30.4-0.6-0.00.7-0.60.6-0.4-0.6-0.5-0.3
Short access total infusions0.50.72.4-1.50.20.90.3-0.30.80.31.00.9
Short access day 1 locomotion0.10.10.5-0.70.10.5-0.10.2-0.0-0.2-0.10.1
Short access day 10 total locomotion1.14.37.81.4-2.3-1.4-2.82.8-2.2-2.6-1.50.1
Short access total locomotion0.60.81.9-0.2-0.90.3-1.31.4-1.0-1.2-0.70.3
One hour access (0.3 mA shock)0.50.61.7-1.31.01.30.4-0.40.80.4-0.0-0.0
Compulsive drug intake0.40.72.8-0.2-0.2-0.60.4-0.40.90.61.71.0
One hour access (shock baseline)0.20.41.7-0.50.90.9-0.10.1-0.1-0.1-1.3-0.6
Social response proportion5.67.112.62.7-3.6-2.6-3.33.2-2.7-2.8-0.30.9
Social responses1.82.34.11.3-2.0-1.5-1.81.9-1.5-1.8-0.5-0.2
Social time0.40.61.60.7-1.2-1.3-0.80.8-0.5-0.7-0.30.3
Soleus weight0.61.93.7-0.81.01.60.9-1.30.91.61.91.8
Bone: stiffness0.40.72.40.41.0-0.30.2-0.50.10.2-1.6-1.3
Tibialis anterior weight1.75.911.72.4-3.4-2.6-3.12.8-1.9-2.50.51.4
Time to tail flick, vehicle, before self-admin0.10.10.20.40.40.30.1-0.2-0.30.10.2-0.2
Time to tail flick, vehicle, after self-admin0.20.41.10.21.11.00.1-0.2-0.50.1-0.8-0.8
Time to tail flick, test, before self-admin0.91.01.60.4-0.7-0.5-1.21.2-1.0-1.2-1.3-1.0
Time to tail flick, test, after self-admin0.80.81.61.0-1.0-1.3-1.00.9-0.6-1.1-0.7-0.3
Delta time to tail flick, vehicle, before/after SA0.20.20.80.00.30.3-0.20.1-0.5-0.4-0.9-0.6
Delta time to tail flick, test, before/after SA0.20.31.00.6-0.3-0.50.1-0.20.10.20.91.0
Tibia length0.20.41.30.31.20.50.3-0.5-0.10.6-1.2-0.5
Ambulatory time before self-admin0.10.30.9-0.80.20.90.2-0.20.40.30.80.1
Ambulatory time after self-admin0.61.01.7-1.10.80.51.3-1.21.31.20.6-0.1
Bone: tissue strength0.40.40.90.9-0.1-0.4-0.50.2-0.7-0.3-0.9-0.8
Total heroin consumption0.60.61.61.3-0.3-0.6-0.80.9-1.2-0.5-0.90.1
Bone: trabecular number0.00.10.10.00.2-0.10.3-0.30.40.30.10.1
Bone: trabecular spacing1.11.62.21.2-1.2-1.2-1.21.2-1.4-1.5-1.3-1.2
Bone: trabecular thickness1.21.62.91.7-1.5-1.3-1.41.3-1.3-0.9-0.01.3
Bone: trabecular tissue density0.20.31.2-0.5-1.1-0.7-0.40.30.4-0.60.40.1
Water consumed over 24 hours1.22.35.8-2.31.30.91.3-1.21.80.5-0.6-2.4
Number of responses in last shaping day0.40.62.5-1.60.41.20.5-0.50.60.20.40.1