Hub : Genes

LOC120100025

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_234370167_234370922 0.03 0.02 3.0e-04 0.03 0.03 0.01 0.02 4.4e-04 3.7e-04 7.4e-03 7.1e-04
2 NAcc gene expression LOC120100025 0.26 0.1 0.0e+00 0.31 0.29 0.31 0.31 3.7e-36 3.2e-34 1.7e-36 1.0e-36
3 Adipose gene expression LOC120100025 0.15 0.07 0.0e+00 0.16 0.15 0.16 0.03 5.7e-18 1.4e-16 8.0e-18 2.0e-04
4 PL intron excision ratio chr1_234370167_234370922 0.03 0.02 2.8e-03 0.02 0.01 0.02 0.01 3.2e-03 8.8e-03 6.7e-03 9.9e-03
5 PL gene expression LOC120100025 0.42 0.11 0.0e+00 0.31 0.31 0.32 0.32 1.2e-34 1.8e-34 6.9e-36 1.5e-36
6 Brain gene expression LOC120100025 0.22 0.07 0.0e+00 0.28 0.27 0.29 0.24 4.0e-26 4.7e-25 2.8e-27 9.1e-22
7 pVTA gene expression LOC120100025 0.17 0.08 4.7e-08 0.17 0.19 0.17 0.17 8.2e-08 1.7e-08 7.3e-08 1.1e-07
8 BLA gene expression LOC120100025 0.33 0.12 1.1e-16 0.27 0.28 0.28 0.29 7.9e-15 1.7e-15 3.1e-15 7.4e-16
9 OFC gene expression LOC120100025 0.61 0.28 6.2e-09 0.2 0.34 0.32 0.31 1.7e-05 6.1e-09 2.8e-08 4.6e-08
10 IL gene expression LOC120100025 0.23 0.11 2.0e-05 0.19 0.15 0.14 0.14 2.1e-05 2.0e-04 3.6e-04 3.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density9.515.817.03.94.0-4.0-3.94.0-4.04.14.04.0-3.7
Area under the delay curve0.30.31.0-0.2-0.70.50.6-0.90.4-1.0-0.5-0.20.2
BMI with tail0.10.41.80.50.8-1.3-0.50.7-0.70.50.2-0.2-0.2
BMI without tail0.00.10.30.40.3-0.5-0.20.1-0.40.1-0.0-0.3-0.3
Body weight0.72.97.52.32.0-2.7-1.81.3-2.10.71.0-0.0-1.3
Weight adjusted by age0.30.40.70.10.4-0.5-0.70.6-0.50.60.80.8-0.8
Bone surface4.27.38.92.82.7-2.7-2.62.7-2.73.02.72.7-2.6
Bone volume6.010.211.73.33.2-3.4-3.23.1-3.43.23.22.8-3.2
Breakpoint value in progressive ratio session0.91.01.61.21.1-1.2-1.10.9-1.10.50.80.6-0.9
Number of licking bursts2.42.84.1-1.8-1.71.61.7-1.71.5-2.0-1.7-1.61.4
Context. condit. distance diff. score2.12.53.71.91.5-1.9-1.51.5-1.91.31.40.1-1.8
Locomotion velocity, session 12.02.14.2-2.0-1.51.31.5-1.51.5-1.1-1.4-0.61.7
Locomotion distance, session 10.10.20.3-0.5-0.50.30.5-0.30.4-0.2-0.3-0.30.6
Locomotion velocity, session 20.91.01.3-1.1-1.01.11.0-1.01.0-0.8-1.0-1.00.9
Locomotion distance, session 20.60.92.3-0.7-0.80.90.8-0.80.8-1.0-0.8-1.50.9
Locomotion velocity, session 30.10.10.30.40.3-0.2-0.30.1-0.40.10.2-0.5-0.5
Locomotion distance, session 30.30.31.20.80.3-0.5-0.30.2-0.50.00.2-1.1-0.5
Stereotopy head waving bouts, day 30.00.10.2-0.20.1-0.00.00.00.10.40.10.5-0.3
Stereotopy head waving duration, day 30.20.21.10.00.3-0.2-0.20.2-0.20.50.41.1-0.6
Locomotion velocity, session 70.60.71.31.10.8-0.7-0.90.9-0.90.40.90.2-1.0
Locomotion distance, session 70.81.01.61.31.0-1.0-1.01.1-1.10.61.00.6-1.0
Stereotopy head waving bouts, day 70.10.10.2-0.4-0.30.50.4-0.50.4-0.1-0.4-0.40.2
Stereotopy head waving duration, day 70.00.10.1-0.3-0.20.10.3-0.30.20.1-0.3-0.10.1
Locomotion velocity, session 80.20.30.40.60.5-0.6-0.50.6-0.50.50.40.6-0.4
Locomotion distance, session 80.30.50.90.90.7-0.7-0.80.7-0.80.40.6-0.7-0.6
Degree of sensitization distance0.10.10.90.10.2-0.2-0.20.2-0.1-0.10.30.9-0.0
Degree of sensitization stereotypy0.00.00.0-0.0-0.10.20.2-0.20.20.1-0.1-0.20.0
Conditioned locomotion1.01.21.71.01.2-1.0-1.31.1-1.20.91.20.8-1.3
Cocaine response after cond. corrected0.10.10.40.20.1-0.1-0.10.1-0.20.30.2-0.0-0.6
Cocaine response after cond. not corrected0.10.10.30.50.2-0.3-0.10.1-0.30.10.1-0.2-0.5
Cocaine response before conditioning0.40.51.1-0.1-0.60.30.7-0.70.5-1.0-0.8-0.61.0
Saline control response0.00.10.20.3-0.00.00.1-0.0-0.1-0.20.0-0.3-0.5
Bone: connectivity density5.58.712.72.72.9-2.8-2.73.1-2.83.42.93.6-2.5
Bone: cortical apparent density1.21.62.8-1.5-1.41.71.4-1.21.4-1.0-1.2-0.50.8
Bone: cortical area2.03.05.52.31.8-2.3-1.71.3-2.11.21.40.1-1.9
Bone: cortical porosity0.20.20.5-0.5-0.40.70.4-0.30.5-0.4-0.3-0.30.4
Bone: cortical porosity0.00.00.0-0.00.00.1-0.1-0.00.1-0.10.0-0.10.1
Bone: cortical thickness0.20.31.50.60.2-0.7-0.1-0.3-0.4-0.5-0.3-1.2-0.5
Bone: cortical thickness0.50.52.2-0.4-0.50.40.5-0.80.3-0.9-0.7-1.5-0.3
Bone: cortical tissue density1.21.62.8-1.5-1.41.71.4-1.21.4-1.0-1.1-0.50.8
Condit. Reinf. active minus inactive responses1.11.32.7-0.9-1.20.91.1-1.30.9-1.4-1.1-1.70.7
Condit. Reinf. active-inactive response ratio1.21.31.9-1.4-1.31.01.2-1.21.2-1.0-1.1-0.91.2
Condit. Reinf. active responses0.20.21.50.3-0.2-0.20.1-0.4-0.2-0.6-0.1-1.2-0.5
Condit. Reinf. inactive responses1.01.22.71.51.1-1.1-1.10.8-1.30.60.9-0.2-1.6
Incentive salience index mean1.72.05.4-0.9-1.40.91.3-1.61.0-1.8-1.4-2.31.0
Condit. Reinf. lever presses1.82.55.7-1.1-1.51.11.4-1.71.2-1.9-1.5-2.41.4
Condit. Reinf. active minus inactive responses0.30.31.00.90.5-0.3-0.50.2-0.6-0.10.3-1.0-0.6
Condit. Reinf. active-inactive response ratio0.10.10.50.30.10.3-0.2-0.1-0.2-0.20.0-0.7-0.3
Condit. Reinf. active responses1.11.53.21.81.3-1.2-1.31.0-1.50.81.1-0.2-1.5
Condit. Reinf. inactive responses1.01.22.31.51.1-1.5-1.00.9-1.31.00.90.3-1.2
Condit. Reinf. lever presses0.10.20.50.50.4-0.2-0.50.2-0.50.30.4-0.1-0.7
Condit. Reinf. lever reinforcers received0.70.92.01.41.0-0.9-1.00.7-1.20.60.8-0.4-1.2
Conditioned reinforcement - actives2.22.23.31.61.7-1.5-1.61.6-1.31.31.41.8-1.0
Conditioned reinforcement - inactives2.83.14.21.71.9-1.7-1.81.9-1.61.91.72.0-1.3
Conditioned locomotion1.31.53.11.01.4-1.3-1.21.4-0.91.51.01.8-0.5
Patch foraging indifference point 0 sec0.20.30.6-0.4-0.10.30.3-0.50.5-0.8-0.7-0.60.7
Patch foraging indifference point AUC1.71.93.1-1.0-1.51.21.6-1.61.3-1.6-1.8-1.01.1
Delay disc. indifference point, 0s delay0.20.20.50.70.2-0.6-0.30.0-0.6-0.30.4-0.2-0.7
Delay disc. indifference point, 16s delay0.20.20.70.60.1-0.1-0.20.1-0.40.10.40.9-0.6
Delay disc. indifference point, 2s delay0.10.10.40.0-0.00.3-0.0-0.1-0.0-0.00.30.6-0.4
Delay disc. indifference point, 24s delay1.61.62.9-0.7-1.41.11.2-1.71.0-1.7-1.4-1.01.1
Delay disc. indifference point, 4s delay0.10.10.60.2-0.30.20.3-0.50.1-0.8-0.2-0.3-0.1
Delay disc. indifference point, 8s delay1.92.02.9-1.3-1.61.51.5-1.71.4-1.7-1.4-0.51.2
Indifference point function ln k2.02.83.91.52.0-1.5-1.91.8-1.71.72.00.4-1.5
Indifference point function log k2.02.83.91.52.0-1.5-1.91.8-1.71.72.00.4-1.5
Patch foraging total patch changes 0 sec0.10.20.5-0.3-0.10.20.3-0.50.4-0.7-0.7-0.60.6
Patch foraging total patch changes 12 sec1.92.53.4-1.5-1.61.51.8-1.71.7-1.6-1.8-0.81.5
Patch foraging total patch changes 18 sec0.40.61.1-0.6-0.70.60.8-0.90.6-1.0-1.0-0.70.4
Patch foraging total patch changes 24 sec0.60.71.8-0.4-0.61.00.6-1.10.8-1.4-1.0-0.80.6
Patch foraging total patch changes 6 sec1.72.54.0-1.4-1.61.31.7-1.81.6-1.8-2.0-0.81.6
Patch foraging time to switch 0 sec0.50.81.8-1.3-0.91.20.9-0.81.0-0.7-0.6-0.50.9
Patch foraging water rate 0 sec0.20.30.60.80.6-0.7-0.70.5-0.50.30.4-0.5-0.5
Patch foraging water rate 12 sec0.30.41.20.80.9-1.1-0.70.8-0.60.40.40.1-0.2
Patch foraging water rate 18 sec0.70.91.61.21.2-1.1-1.31.1-0.80.71.00.4-0.4
Patch foraging water rate 24 sec1.01.32.61.61.3-1.6-1.31.1-1.30.60.9-0.0-1.0
Patch foraging water rate 6 sec0.10.10.40.30.4-0.3-0.40.4-0.30.40.30.0-0.6
Seeking ratio, delayed vs. immediate footshock0.00.00.10.10.1-0.20.1-0.1-0.2-0.1-0.1-0.3-0.2
Distance traveled before self-admin0.40.41.0-0.3-0.60.90.7-0.60.5-0.6-0.7-1.00.4
Distance traveled after self-admin1.31.53.40.71.0-0.6-0.71.2-1.01.61.41.9-1.4
Extensor digitorum longus weight0.20.71.91.40.9-0.8-0.90.6-1.00.00.6-0.3-0.7
Bone: elastic displacement1.31.53.4-1.8-1.21.81.1-0.81.5-0.5-0.8-0.21.2
Bone: elastic work0.40.61.9-1.2-0.61.40.5-0.20.90.1-0.20.30.8
Bone: endosteal estimation4.610.011.63.43.3-2.8-3.43.2-3.23.43.42.7-2.8
Bone: endosteal perimeter5.210.712.73.33.4-3.3-3.63.4-3.33.63.52.6-2.7
Epididymis fat weight0.10.20.60.60.5-0.7-0.5-0.0-0.4-0.3-0.1-0.8-0.1
Delta time in closed arm before/after self-admin2.22.15.1-1.2-1.10.61.2-1.51.1-1.7-1.6-2.31.5
Delta time in open arm before/after self-admin0.70.61.50.70.4-0.1-0.60.6-0.70.91.10.9-1.2
Diff in mean of infusions in LGA sessions0.10.20.40.40.4-0.6-0.60.2-0.4-0.00.1-0.5-0.3
Delay discount exponential model param0.40.41.20.30.8-0.6-0.71.0-0.51.10.60.2-0.3
Extinction: sum of active levers before priming0.10.10.60.40.2-0.8-0.00.0-0.4-0.1-0.0-0.3-0.2
Active lever presses in extinction session 61.81.82.21.41.4-1.2-1.41.4-1.41.11.40.9-1.5
Bone: final force0.50.81.51.21.0-1.1-1.00.7-1.00.70.70.3-0.7
Bone: final moment0.50.81.31.11.0-0.9-1.00.7-1.00.80.80.6-0.6
Food consumed during 24 hour testing period0.30.40.7-0.4-0.50.40.6-0.70.5-0.7-0.7-0.70.9
Glucose0.00.00.20.10.2-0.4-0.1-0.1-0.1-0.1-0.1-0.00.0
Heart weight0.20.20.7-0.5-0.40.10.3-0.70.5-0.4-0.5-0.10.9
Delay discount hyperbolic model param0.40.41.00.30.7-0.6-0.70.9-0.51.00.50.1-0.3
Intermittent access intake day 1-15 change2.22.23.21.31.7-1.8-1.41.8-1.21.61.21.6-0.9
Intermittent access intake escalation1.81.83.21.11.6-1.8-1.31.6-1.01.41.01.4-0.6
Intermittent access intake escalation 20.80.81.40.61.1-1.2-1.01.2-0.61.00.60.8-0.3
Intermitt. access day 1 inactive lever presses0.30.40.70.40.40.3-0.60.5-0.50.80.90.7-0.8
Intermitt. access day 15 inactive lever presses2.83.06.51.41.4-1.3-1.51.7-1.52.21.82.6-1.7
Intermitt. access escalation Index0.30.20.6-0.2-0.50.10.5-0.50.4-0.6-0.8-0.50.4
Intermittent access day 1 total infusions1.01.11.61.31.2-0.9-1.11.2-1.00.81.00.9-0.9
Intermittent access day 15 total infusions3.23.65.72.12.3-2.4-1.92.2-1.71.71.41.8-1.0
Intermittent access terminal intake (last 3 days)2.02.23.51.51.8-1.8-1.51.9-1.21.41.11.6-0.7
Intermittent access total infusions1.71.92.91.51.7-1.6-1.31.7-1.31.21.11.2-0.8
Intermittent access day 1 locomotion0.50.51.01.00.9-0.7-0.80.8-0.80.40.60.2-0.5
Intermittent access day 15 total locomotion1.51.62.21.11.3-1.4-1.21.5-1.11.41.11.3-0.8
Intermittent access total locomotion0.40.50.90.70.9-0.8-0.71.0-0.70.60.60.5-0.3
Intermittent access standard deviation1.11.11.90.91.3-1.4-1.11.2-0.81.20.91.1-0.5
Left kidney weight0.20.51.80.60.4-1.1-0.3-0.2-0.4-0.7-0.4-1.30.4
Right kidney weight0.41.22.7-0.3-0.6-0.30.7-1.20.6-1.6-1.4-1.51.5
Cocaine induced anxiety0.00.00.00.0-0.20.1-0.1-0.2-0.0-0.20.10.0-0.0
Post-drug Anxiety0.10.10.8-0.1-0.30.30.2-0.20.00.20.30.9-0.3
Baseline Anxiety0.10.10.4-0.1-0.20.30.2-0.10.10.30.30.6-0.3
Tail length0.20.62.21.50.8-0.6-0.90.2-1.0-0.20.4-0.3-1.0
Length with tail0.62.15.62.41.7-1.9-1.60.9-1.80.20.9-0.0-1.3
Length without tail0.91.94.12.01.6-2.0-1.51.1-1.70.51.1-0.1-0.9
Times rat made contact with spout0.10.10.20.50.3-0.0-0.40.2-0.4-0.10.4-0.1-0.4
Lifetime Intake1.31.42.41.31.5-1.3-1.11.6-1.01.01.01.2-0.7
Liver weight, left1.62.65.22.11.8-2.3-1.71.4-1.90.91.30.0-1.3
Liver weight, right0.20.41.01.00.8-0.9-0.70.4-0.5-0.5-0.1-0.50.1
Locomotor activity0.40.61.1-1.0-0.71.10.6-0.60.7-0.6-0.6-0.90.6
Locomotor testing distance0.81.31.9-1.4-1.11.31.1-0.91.2-0.9-1.0-1.21.0
Locomotor testing rearing0.10.10.40.20.3-0.1-0.20.3-0.20.10.1-0.7-0.3
Locomotion in novel chamber2.32.93.81.41.8-1.5-1.72.0-1.71.91.80.8-1.9
Locomotion in novel chamber post-restriction2.02.44.12.01.5-1.4-1.61.5-1.71.21.40.1-2.0
Fecal boli incidents, locomotor time 10.10.10.30.30.2-0.5-0.30.2-0.10.1-0.00.60.3
Change in fecal boli incidents, locomotor task0.20.20.5-0.2-0.40.70.2-0.30.5-0.3-0.3-0.30.4
Time >=10cm from walls, locomotor time 12.02.14.42.11.4-1.8-1.21.2-1.71.11.20.2-1.6
Bouts of movement, locomotor time 10.40.40.90.50.9-0.9-0.90.8-0.60.30.30.0-0.3
Total resting periods, locomotor time 10.50.61.20.71.1-1.0-1.01.0-0.70.40.40.3-0.4
Rest time, locomotor task time 10.30.41.30.10.6-0.5-0.70.8-0.30.60.51.1-0.2
Distance moved, locomotor task time 10.91.02.4-0.2-1.01.20.8-1.20.7-1.1-0.8-1.60.2
Vertical activity count, locomotor time 10.10.10.4-0.1-0.30.40.2-0.40.1-0.3-0.3-0.7-0.1
Time >=10cm from walls, locomotor time 20.10.10.50.70.1-0.2-0.1-0.1-0.3-0.4-0.1-0.2-0.1
Bouts of movement, locomotor time 21.61.72.8-1.4-0.91.21.0-1.01.4-1.7-1.5-0.91.6
Total resting periods, locomotor time 21.71.83.2-1.5-0.91.20.9-1.11.5-1.8-1.5-1.01.7
Rest time, locomotor task time 20.00.10.2-0.20.1-0.2-0.10.00.1-0.5-0.2-0.20.4
Distance moved, locomotor task time 20.20.21.00.4-0.40.60.3-0.50.1-0.2-0.2-1.0-0.4
Vertical activity count, locomotor time 20.30.30.5-0.4-0.70.60.6-0.70.7-0.4-0.60.10.6
Light reinforcement 10.61.22.10.71.1-0.8-1.21.0-1.01.11.11.4-1.0
Light reinforcement 20.91.22.8-1.7-1.21.31.0-0.91.3-0.6-0.80.41.1
Bone: marrow area5.010.712.33.53.4-2.9-3.53.3-3.33.53.52.8-2.9
Bone: maximum diameter8.916.318.74.34.2-4.3-4.13.9-4.34.14.12.6-4.2
Bone: maximum force1.83.14.32.11.9-1.9-1.91.6-1.91.71.71.2-1.5
Bone: maximum moment1.62.83.61.91.8-1.7-1.81.6-1.81.81.71.4-1.4
Mean time between licks in bursts1.21.62.5-1.6-1.21.41.3-1.21.4-1.0-1.2-0.61.5
Mean num. licks in bursts2.32.73.71.91.7-1.4-1.81.6-1.51.81.81.4-1.5
Cd content in liver0.50.60.8-0.7-0.80.70.8-0.80.8-0.6-0.9-0.50.9
Co content in liver0.30.40.8-0.9-0.70.80.6-0.30.70.2-0.30.80.5
Cu content in liver1.61.93.3-1.8-1.41.81.4-1.21.7-0.9-1.10.31.4
Fe content in liver5.06.06.7-2.6-2.42.62.4-2.52.5-2.4-2.4-2.22.5
K content in liver0.10.10.3-0.4-0.30.50.2-0.10.3-0.5-0.2-0.00.4
Mg content in liver1.11.11.7-1.1-1.11.31.0-1.01.1-1.1-1.0-0.80.8
Mn content in liver1.92.22.5-1.5-1.51.51.5-1.51.6-1.6-1.5-0.91.5
Na content in liver2.12.23.7-1.3-1.41.61.4-1.41.4-1.7-1.4-1.91.2
Rb content in liver0.00.10.20.30.10.0-0.30.1-0.2-0.10.2-0.3-0.4
Se content in liver24.730.236.1-6.0-5.65.75.7-5.55.9-5.2-5.5-3.85.6
Sr content in liver0.80.72.00.40.6-0.5-0.60.9-0.61.30.81.4-0.7
Zn content in liver11.012.113.3-3.6-3.53.63.6-3.33.7-3.4-3.5-3.03.5
Bone: minimum diameter5.09.413.63.73.2-3.6-3.22.9-3.32.92.91.7-2.7
Time in familiar zone, hab. session 10.10.10.40.10.2-0.2-0.30.4-0.10.50.40.6-0.2
Time in novel zone, hab. session 10.60.61.1-0.8-0.71.00.8-0.80.8-0.9-0.8-0.60.6
Total zone transitions, hab. session 10.10.10.30.30.3-0.2-0.30.4-0.30.40.50.3-0.6
Total locomotion distance, hab. session 10.30.41.1-0.8-0.61.00.5-0.50.6-0.7-0.3-0.90.2
Locomotion velocity, hab. session 10.50.71.5-0.9-0.81.20.7-0.70.8-0.9-0.5-1.20.5
Time in familiar zone, hab. session 20.20.20.4-0.7-0.50.30.5-0.40.5-0.3-0.40.10.6
Time in novel zone, hab. session 20.10.10.20.20.2-0.1-0.20.2-0.20.20.20.3-0.4
Total zone transitions, hab. session 20.50.70.8-0.8-0.90.70.8-0.90.8-0.7-0.8-0.90.9
Total locomotion distance, hab. session 20.81.02.0-1.1-1.00.91.0-0.90.9-0.9-0.9-1.41.0
Locomotion velocity, hab. session 20.81.12.4-1.0-1.01.00.9-0.90.9-1.0-0.9-1.61.0
Novel to familiar place preference ratio1.11.22.01.11.3-0.8-1.21.1-1.01.01.11.4-0.8
Novelty place preference1.41.52.71.11.4-0.8-1.31.2-1.01.21.21.7-0.9
Time in novel zone, NPP test1.01.02.40.81.1-0.6-1.11.0-0.80.91.01.6-0.7
Total zone transitions, NPP test1.01.42.4-1.0-1.10.91.1-1.21.0-1.3-1.1-1.61.1
Total locomotion distance, NPP test1.52.13.7-1.4-1.41.61.3-1.51.4-1.5-1.3-1.91.0
Locomotion velocity, NPP test1.42.04.3-1.2-1.31.51.2-1.41.3-1.5-1.3-2.11.0
Intraocular pressure0.40.61.10.70.8-0.3-0.90.7-0.70.70.70.7-1.0
Delta distance traveled before/after self-admin3.13.34.91.41.7-1.8-1.71.9-1.72.02.02.2-1.8
Delta ambulatory time before/after self-admin4.75.16.82.02.2-2.3-2.12.2-2.22.42.42.6-2.3
Parametrial fat weight0.10.30.70.80.6-0.8-0.50.2-0.5-0.30.0-0.5-0.1
Pavlov. Cond. lever latency0.70.93.20.40.7-0.4-0.80.8-0.51.30.91.8-0.9
Pavlov. Cond. magazine entry latency2.32.96.0-1.4-1.60.91.7-1.71.4-1.9-1.8-2.51.9
Pavlov. Cond. change in total contacts2.83.05.9-1.4-1.71.01.8-1.81.5-1.8-1.9-2.41.8
Pavlov. Cond. index score1.51.96.3-0.7-1.10.41.1-1.30.8-1.8-1.3-2.51.4
Pavlov. Cond. latency score1.31.76.6-0.5-1.00.41.0-1.20.6-1.8-1.2-2.61.2
Pavlov. Cond. lever contacts1.31.64.9-0.6-1.00.61.1-1.20.8-1.6-1.2-2.21.3
Pavlov. Cond. magazine entry number1.11.32.90.91.0-0.2-1.11.2-0.81.31.21.7-1.5
Pavlov. Cond. intertrial magazine entries0.50.61.61.10.8-0.6-0.80.6-0.90.50.80.2-1.3
Pavlov. Cond. lever-magazine prob. diff.2.12.67.2-1.0-1.40.71.4-1.61.1-2.0-1.6-2.71.8
Pavlov. Cond. response bias2.22.74.8-1.4-1.60.81.6-1.61.4-1.8-1.7-2.22.0
Pavlov. Cond. lever latency0.00.10.20.20.4-0.3-0.30.4-0.20.10.2-0.00.1
Pavlov. Cond. magazine entry latency1.01.22.3-0.9-1.10.81.2-1.20.9-1.2-1.2-1.50.6
Pavlov. Cond. change in total contacts0.10.20.6-0.1-0.40.30.2-0.60.2-0.6-0.3-0.80.1
Pavlov. Cond. index score0.10.20.6-0.1-0.40.20.3-0.60.1-0.6-0.4-0.8-0.2
Pavlov. Cond. latency score0.10.10.40.1-0.20.00.1-0.4-0.1-0.3-0.2-0.6-0.4
Pavlov. Cond. lever contacts0.00.00.1-0.1-0.30.00.2-0.40.1-0.1-0.2-0.2-0.2
Pavlov. Cond. magazine entry number2.12.64.31.41.6-1.4-1.61.8-1.41.81.62.1-1.1
Pavlov. Cond. intertrial magazine entries0.70.91.51.21.1-0.9-1.10.9-1.10.50.90.2-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.2-0.50.20.5-0.70.2-0.7-0.5-1.0-0.1
Pavlov. Cond. response bias0.70.91.5-0.8-1.10.81.0-1.20.8-1.1-1.0-1.10.5
Time in closed arm before self-admin0.10.10.7-0.10.10.4-0.10.40.10.20.20.8-0.2
Time in closed arm after self-admin1.61.62.8-1.0-1.21.11.3-1.21.2-1.7-1.4-1.41.1
Time in open arm before self-admin0.20.20.4-0.4-0.2-0.10.4-0.40.2-0.4-0.6-0.60.6
Time in open arm after self-admin1.71.82.61.11.3-1.1-1.31.4-1.31.61.51.3-1.5
Bone: periosteal estimation5.010.413.43.73.4-3.3-3.43.1-3.53.23.22.1-3.1
Bone: periosteal perimeter4.57.410.03.22.9-3.0-2.92.6-2.92.62.71.3-2.5
Bone: post-yield work1.52.04.12.01.5-2.0-1.41.0-1.71.01.10.6-1.1
Progressive ratio test 1 active lever presses1.71.82.41.41.4-1.2-1.21.5-1.21.41.41.5-1.3
Progressive ratio test 1 breakpoint1.61.62.41.31.3-1.1-1.11.5-1.11.31.31.4-1.2
Progressive ratio test 1 inactive lever presses2.73.04.11.72.0-1.6-1.82.0-1.51.51.52.0-1.3
Progressive ratio test 2 active lever presses4.04.35.82.22.4-2.2-2.22.4-2.02.01.81.9-1.7
Progressive ratio test 2 breakpoint5.35.97.62.52.7-2.5-2.52.8-2.32.42.22.2-2.1
Progressive ratio test 2 inactive lever presses3.33.85.81.72.0-1.7-1.92.3-1.72.11.92.4-1.6
Incentive Sensitization - Responses4.34.46.52.12.5-2.3-2.42.5-2.01.91.71.8-1.4
Incentive Sensitization - Breakpoint4.64.76.72.22.6-2.4-2.42.5-2.02.01.71.9-1.5
Sum of active levers in priming session hrs 5-60.20.21.2-0.4-0.20.20.10.20.30.40.21.1-0.1
Progressive ratio0.10.20.80.50.4-0.50.10.2-0.4-0.1-0.3-0.9-0.0
Food seeking constrained by brief footshock0.91.12.81.21.2-1.7-1.00.9-1.20.70.8-0.2-0.5
Seeking ratio, punishment vs. effort0.00.00.1-0.0-0.10.0-0.2-0.20.1-0.00.30.30.0
Retroperitoneal fat weight0.10.30.60.70.6-0.8-0.70.2-0.70.20.3-0.6-0.5
Reaction time number correct2.33.44.81.61.7-1.7-2.11.8-1.81.62.21.9-1.8
Reaction time mean minus median0.10.10.4-0.10.1-0.60.10.2-0.00.6-0.20.20.2
Reaction time mean minus median AUC0.10.10.1-0.4-0.20.00.4-0.10.30.4-0.30.10.3
Reaction time num false alarms0.40.51.01.00.7-0.5-0.90.5-0.80.20.6-0.2-0.9
Reaction time num false alarms AUC0.10.10.40.50.3-0.1-0.50.1-0.4-0.20.2-0.6-0.5
Reaction time trials correct on left2.33.44.81.61.7-1.7-2.11.8-1.81.62.21.9-1.8
Reaction time trials on left2.33.24.61.61.7-1.7-2.11.7-1.71.52.11.9-1.8
Reaction time mean2.63.65.7-2.1-2.01.72.4-1.91.9-1.4-2.0-1.41.9
Reaction time mean AUC3.24.36.6-2.4-2.21.92.6-2.02.2-1.5-2.2-1.42.2
Median of all reaction times3.54.87.1-2.5-2.32.22.7-2.22.2-1.6-2.2-1.52.1
Reaction time omissions0.30.31.3-0.3-0.60.20.8-0.60.3-0.3-0.6-1.2-0.1
Reaction time false alarm rate0.20.31.50.0-0.20.50.2-0.40.2-0.6-0.5-1.20.1
Reaction time premature initiation rate0.71.01.81.11.2-1.4-0.91.0-1.00.70.80.6-0.9
Reaction time premature initiations3.14.36.02.22.2-2.5-2.22.1-2.11.72.11.7-2.0
Std. dev. reaction times0.60.81.8-1.0-1.00.41.3-0.90.9-0.4-1.1-0.70.9
Reaction time trials completed2.33.24.61.61.7-1.7-2.11.7-1.71.52.11.9-1.8
Reaction time trials AUC1.72.43.61.41.5-1.5-1.81.5-1.51.21.91.6-1.5
Run reversals in cocaine runway, females0.10.10.1-0.40.10.1-0.20.3-0.00.40.20.3-0.1
Run reversals in cocaine runway, males0.40.40.7-0.5-0.50.40.6-0.70.5-0.7-0.8-0.60.8
Latency to leave start box in cocaine runway1.11.23.71.20.9-0.7-0.80.9-1.31.01.1-0.2-1.9
Latency to leave start box in cocaine runway, F0.30.31.20.60.50.0-0.40.5-0.50.40.4-0.6-1.1
Latency to leave start box in cocaine runway, M0.90.92.01.00.8-1.0-0.60.7-1.20.81.00.3-1.4
Std. dev. time between licks in bursts2.73.24.5-2.1-1.81.91.8-1.81.9-1.6-1.7-1.12.0
Total sessions with >9 infusions0.20.20.50.40.7-0.7-0.20.7-0.20.1-0.00.30.1
Short access day 1 total inactive lever presses2.32.65.21.01.6-1.2-1.41.8-1.32.01.62.3-1.4
Short access day 10 total inactive lever presses0.30.31.0-0.6-0.61.00.3-0.40.7-0.4-0.40.30.4
Short access day 1 total infusions0.00.10.1-0.10.00.10.20.10.3-0.3-0.30.10.4
Short access day 10 total infusions0.10.10.7-0.20.10.10.20.20.4-0.3-0.30.30.9
Short access total infusions0.60.61.20.81.1-0.8-0.71.1-0.60.50.61.0-0.3
Short access day 1 locomotion0.30.40.9-0.3-0.3-0.10.7-0.30.5-0.8-1.0-0.60.9
Short access day 10 total locomotion0.00.10.3-0.20.10.2-0.10.00.1-0.2-0.1-0.50.3
Short access total locomotion0.20.20.6-0.5-0.20.20.5-0.10.4-0.6-0.5-0.40.7
One hour access (0.3 mA shock)7.79.111.93.13.4-3.3-3.33.3-2.82.82.73.0-2.2
Compulsive drug intake1.11.12.11.50.9-1.2-1.00.6-1.40.61.00.7-1.4
One hour access (shock baseline)1.71.93.61.11.8-1.6-1.41.9-1.01.41.01.6-0.3
Social response proportion0.70.71.50.20.9-0.8-0.71.0-0.71.21.01.2-0.5
Social responses1.11.43.40.81.2-1.2-1.21.3-0.91.51.11.8-0.5
Social time1.01.32.5-1.1-1.00.91.2-1.11.2-1.2-1.4-0.51.6
Soleus weight1.02.94.31.51.5-1.7-1.51.7-1.62.11.71.9-1.6
Bone: stiffness1.72.65.02.21.8-2.1-1.81.4-1.91.11.40.6-1.2
Tibialis anterior weight0.41.33.01.71.3-1.0-1.31.1-1.40.31.00.1-1.2
Time to tail flick, vehicle, before self-admin0.20.20.5-0.7-0.40.50.4-0.30.6-0.2-0.30.50.4
Time to tail flick, vehicle, after self-admin0.40.40.90.90.8-0.5-0.70.7-0.6-0.10.3-0.3-0.5
Time to tail flick, test, before self-admin2.92.84.11.91.7-2.0-1.71.6-1.91.31.60.9-1.8
Time to tail flick, test, after self-admin0.10.10.2-0.2-0.30.20.1-0.20.3-0.5-0.30.20.2
Delta time to tail flick, vehicle, before/after SA1.71.73.61.91.5-1.3-1.31.3-1.60.61.1-0.5-1.4
Delta time to tail flick, test, before/after SA0.40.30.5-0.5-0.50.50.6-0.50.6-0.7-0.7-0.30.7
Tibia length0.00.10.20.40.3-0.2-0.3-0.0-0.30.10.2-0.3-0.4
Ambulatory time before self-admin1.21.22.1-0.9-1.11.21.1-1.11.0-1.1-1.2-1.50.9
Ambulatory time after self-admin1.61.82.81.01.2-0.9-1.01.3-1.31.61.51.5-1.7
Bone: tissue strength0.30.31.0-0.6-0.40.30.4-0.30.6-0.0-0.40.81.0
Total heroin consumption1.11.31.91.31.4-1.2-1.21.1-1.00.91.01.2-0.7
Bone: trabecular number6.710.413.73.03.2-3.4-3.13.3-3.23.43.13.7-2.7
Bone: trabecular spacing3.03.95.6-1.7-2.01.61.9-2.21.8-2.4-2.0-2.31.6
Bone: trabecular thickness5.16.06.52.42.5-2.5-2.42.5-2.52.52.52.6-2.2
Bone: trabecular tissue density2.23.13.91.91.9-1.3-2.01.8-1.81.71.91.1-2.0
Water consumed over 24 hours0.20.20.8-0.2-0.30.60.2-0.40.3-0.9-0.3-0.70.5
Number of responses in last shaping day1.71.72.31.31.3-1.5-1.21.4-1.21.31.11.4-1.1