Hub : Genes

LOC120100025

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_243782746_243783501 0.05 0.03 2.2e-08 0.04 0.06 0.07 0.08 1.1e-06 7.0e-09 1.9e-11 4.5e-12
2 PL intron excision ratio chr1_243782746_243783501 0.03 0.03 2.3e-03 0.03 0.02 0.02 0.02 5.2e-04 2.7e-03 1.1e-03 1.9e-03
3 pVTA gene expression LOC120100025 0.12 0.06 5.3e-13 0.18 0.17 0.18 0.18 9.8e-15 1.3e-13 1.9e-14 1.2e-14
4 NAcc gene expression LOC120100025 0.32 0.11 0.0e+00 0.31 0.3 0.3 0.31 1.7e-48 6.4e-47 8.8e-46 9.1e-48
5 PL gene expression LOC120100025 0.44 0.12 0.0e+00 0.33 0.32 0.32 0.33 6.7e-37 2.7e-35 2.9e-36 1.1e-36
6 IC gene expression LOC120100025 0.32 0.13 5.9e-11 0.26 0.26 0.24 0.25 1.5e-11 3.4e-11 1.4e-10 4.6e-11
7 BLA gene expression LOC120100025 0.35 0.13 0.0e+00 0.28 0.28 0.29 0.31 1.7e-15 2.2e-15 8.0e-16 7.8e-17
8 Brain gene expression LOC120100025 0.23 0.08 0.0e+00 0.28 0.28 0.27 0.29 1.0e-25 2.7e-26 1.8e-25 1.6e-27
9 Adipose gene expression LOC120100025 0.15 0.07 0.0e+00 0.14 0.15 0.16 0.04 7.8e-16 8.3e-17 2.0e-17 9.1e-05
10 IL gene expression LOC120100025 0.24 0.12 8.5e-06 0.25 0.18 0.21 0.21 1.0e-06 5.0e-05 1.1e-05 7.6e-06
11 OFC gene expression LOC120100025 0.5 0.18 2.6e-09 0.26 0.37 0.36 0.37 6.3e-07 1.3e-09 2.1e-09 1.3e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density8.916.519.53.7-4.2-4.2-4.2-4.2-4.34.44.2-3.7-4.03.2
Area under the delay curve0.20.20.5-0.10.50.60.50.50.6-0.4-0.30.70.2-0.7
BMI with tail0.20.82.20.5-1.4-0.9-0.9-0.9-0.70.70.9-1.5-0.60.4
BMI without tail0.00.21.20.5-0.30.20.30.30.0-0.10.1-0.6-0.0-1.1
Body weight0.94.18.02.8-2.8-1.8-1.9-1.9-1.91.52.0-2.2-1.4-1.5
Weight adjusted by age0.20.71.60.4-0.6-0.7-0.5-0.5-0.81.00.9-0.8-1.11.3
Bone surface4.58.810.42.6-3.1-3.0-3.0-3.0-3.13.23.0-3.1-2.92.4
Bone volume6.212.314.53.4-3.8-3.6-3.5-3.5-3.83.83.7-3.4-3.62.2
Breakpoint value in progressive ratio session0.10.30.60.7-0.5-0.5-0.5-0.5-0.70.20.4-0.2-0.3-0.7
Number of licking bursts0.82.53.6-1.51.51.61.91.91.6-1.7-1.51.41.6-1.1
Context. condit. distance diff. score2.22.74.52.1-1.8-1.6-1.6-1.6-1.71.61.8-1.3-1.8-0.4
Locomotion velocity, session 12.12.46.4-2.51.11.71.71.71.6-1.4-1.50.51.40.7
Locomotion distance, session 10.10.20.7-0.80.50.40.40.40.5-0.4-0.40.20.30.3
Locomotion velocity, session 20.70.91.3-1.10.91.01.11.11.1-1.1-0.90.30.8-0.2
Locomotion distance, session 20.50.71.3-0.41.00.70.80.80.8-0.9-0.90.80.9-1.2
Locomotion velocity, session 30.10.10.30.5-0.3-0.2-0.1-0.1-0.20.30.4-0.5-0.5-0.6
Locomotion distance, session 30.30.41.51.1-0.5-0.3-0.3-0.3-0.30.30.6-0.5-0.6-1.2
Stereotopy head waving bouts, day 30.10.21.2-0.6-0.00.10.00.00.00.10.0-0.2-0.31.1
Stereotopy head waving duration, day 30.10.21.3-0.6-0.2-0.0-0.1-0.1-0.10.20.10.0-0.41.1
Locomotion velocity, session 70.70.82.21.5-0.8-0.9-0.8-0.8-0.90.70.9-0.4-1.0-0.7
Locomotion distance, session 70.60.82.01.4-0.9-1.0-0.9-0.9-1.00.90.9-0.2-0.8-0.4
Stereotopy head waving bouts, day 70.20.30.7-0.80.50.70.50.50.6-0.5-0.40.10.30.2
Stereotopy head waving duration, day 70.10.10.5-0.7-0.00.40.20.20.3-0.2-0.1-0.50.10.6
Locomotion velocity, session 80.20.30.50.4-0.6-0.7-0.4-0.4-0.50.50.6-0.4-0.70.4
Locomotion distance, session 80.40.61.91.4-0.6-0.8-0.6-0.6-0.80.70.7-0.3-0.8-0.8
Degree of sensitization distance0.10.10.60.0-0.1-0.2-0.1-0.1-0.20.1-0.10.80.20.0
Degree of sensitization stereotypy0.00.00.1-0.40.20.30.20.20.2-0.1-0.0-0.10.00.2
Conditioned locomotion0.80.91.80.8-1.0-1.0-0.9-0.9-1.11.11.2-0.7-1.30.3
Cocaine response after cond. corrected0.10.10.50.1-0.1-0.00.10.1-0.10.20.3-0.7-0.30.5
Cocaine response after cond. not corrected0.10.10.40.7-0.2-0.1-0.0-0.0-0.10.10.3-0.5-0.3-0.3
Cocaine response before conditioning0.60.73.10.30.50.50.50.50.6-0.8-0.71.00.9-1.7
Saline control response0.10.20.91.0-0.1-0.3-0.2-0.2-0.30.30.5-0.1-0.7-0.2
Bone: connectivity density5.08.09.32.3-2.9-3.1-3.1-3.1-2.93.02.8-2.5-2.53.0
Bone: cortical apparent density1.01.52.6-1.61.51.31.31.31.2-1.2-1.01.60.70.2
Bone: cortical area2.94.87.42.7-2.7-2.1-2.1-2.1-2.22.02.3-2.4-2.0-0.4
Bone: cortical porosity0.00.00.10.10.20.00.10.10.1-0.0-0.2-0.20.1-0.1
Bone: cortical porosity0.10.10.30.5-0.1-0.2-0.1-0.1-0.10.1-0.0-0.50.0-0.2
Bone: cortical thickness0.30.61.71.0-1.0-0.5-0.5-0.5-0.50.30.8-0.7-0.6-1.3
Bone: cortical thickness0.20.20.6-0.40.50.50.50.50.3-0.3-0.00.2-0.2-0.8
Bone: cortical tissue density1.01.62.9-1.71.51.31.31.31.2-1.2-1.11.60.80.2
Condit. Reinf. active minus inactive responses1.01.11.6-0.90.91.21.21.21.2-1.1-0.90.80.8-1.3
Condit. Reinf. active-inactive response ratio1.31.42.5-1.61.01.41.31.31.3-1.2-1.20.71.2-0.2
Condit. Reinf. active responses0.10.21.50.4-0.10.30.20.20.2-0.20.2-0.0-0.4-1.2
Condit. Reinf. inactive responses1.11.53.01.7-1.1-1.1-1.1-1.1-1.21.11.4-0.9-1.7-0.5
Incentive salience index mean1.31.74.1-0.70.91.41.41.41.4-1.4-1.11.11.1-2.0
Condit. Reinf. lever presses1.72.64.9-0.91.31.61.61.61.6-1.7-1.51.81.7-2.2
Condit. Reinf. active minus inactive responses0.30.41.11.0-0.4-0.4-0.4-0.4-0.50.50.6-0.7-0.9-1.0
Condit. Reinf. active-inactive response ratio0.10.10.40.30.10.00.00.0-0.20.20.2-0.3-0.4-0.6
Condit. Reinf. active responses1.21.83.21.8-1.2-1.1-1.2-1.2-1.21.31.5-1.6-1.7-0.4
Condit. Reinf. inactive responses0.81.22.01.4-1.3-0.9-1.1-1.1-0.91.01.2-1.3-1.20.2
Condit. Reinf. lever presses0.20.21.30.1-0.2-0.10.10.1-0.30.40.4-1.2-0.70.3
Condit. Reinf. lever reinforcers received0.81.12.01.4-0.9-0.8-0.8-0.8-1.01.01.1-1.4-1.4-0.5
Conditioned reinforcement - actives0.41.52.91.6-1.4-1.4-1.7-1.7-1.21.11.0-0.6-0.60.6
Conditioned reinforcement - inactives0.61.72.91.5-1.4-1.4-1.7-1.7-1.31.41.2-0.7-0.91.0
Conditioned locomotion1.01.42.21.0-1.1-1.3-1.5-1.5-1.11.11.0-1.4-0.61.3
Patch foraging indifference point 0 sec0.10.20.7-0.00.20.30.30.30.2-0.5-0.50.60.7-0.8
Patch foraging indifference point AUC0.82.03.9-1.41.21.41.11.11.6-1.6-1.22.01.1-1.3
Delay disc. indifference point, 0s delay0.30.41.41.2-0.5-0.3-0.4-0.4-0.30.50.70.2-0.7-1.0
Delay disc. indifference point, 16s delay0.10.10.30.3-0.3-0.3-0.2-0.2-0.20.50.4-0.2-0.60.3
Delay disc. indifference point, 2s delay0.10.10.2-0.00.40.00.10.1-0.10.20.20.1-0.50.5
Delay disc. indifference point, 24s delay1.21.82.9-1.11.01.61.21.21.3-1.4-1.31.61.4-1.7
Delay disc. indifference point, 4s delay0.10.10.90.50.30.10.00.00.2-0.00.10.5-0.1-0.9
Delay disc. indifference point, 8s delay1.21.92.6-1.41.51.61.61.61.5-1.4-1.41.31.1-0.7
Indifference point function ln k0.82.34.21.9-1.4-1.5-1.3-1.3-1.91.71.3-2.0-1.30.6
Indifference point function log k0.82.34.21.9-1.4-1.5-1.3-1.3-1.91.71.3-2.0-1.30.6
Patch foraging total patch changes 0 sec0.10.20.50.00.20.20.20.20.2-0.4-0.40.50.7-0.7
Patch foraging total patch changes 12 sec1.62.12.8-1.61.41.51.31.31.7-1.7-1.41.71.5-0.7
Patch foraging total patch changes 18 sec0.20.41.5-0.60.70.70.50.50.6-0.7-0.41.20.3-0.6
Patch foraging total patch changes 24 sec0.20.82.2-0.21.00.80.90.90.5-0.7-0.71.50.6-1.5
Patch foraging total patch changes 6 sec1.52.63.9-1.81.31.61.51.51.7-1.8-1.62.01.7-1.1
Patch foraging time to switch 0 sec0.20.91.4-1.21.11.11.11.11.0-0.8-1.00.30.80.2
Patch foraging water rate 0 sec0.10.40.70.8-0.7-0.7-0.8-0.8-0.70.60.6-0.1-0.4-0.3
Patch foraging water rate 12 sec0.10.41.00.9-1.0-0.8-0.5-0.5-0.80.40.5-0.9-0.1-0.4
Patch foraging water rate 18 sec0.40.92.81.7-0.9-1.1-0.8-0.8-1.20.90.6-1.2-0.2-0.5
Patch foraging water rate 24 sec1.11.63.71.9-1.6-1.3-1.1-1.1-1.21.01.2-1.3-0.8-0.6
Patch foraging water rate 6 sec0.10.10.3-0.0-0.1-0.5-0.1-0.1-0.40.40.4-0.3-0.40.5
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.30.00.2-0.1-0.10.3-0.4-0.10.70.0-0.4
Distance traveled before self-admin0.10.30.7-0.30.80.60.70.70.5-0.6-0.50.10.3-0.6
Distance traveled after self-admin0.71.25.10.3-0.6-0.9-0.7-0.7-0.81.21.0-1.3-1.22.3
Extensor digitorum longus weight0.31.23.61.9-1.2-1.1-0.7-0.7-1.20.91.00.3-0.9-1.6
Bone: elastic displacement1.51.94.0-2.01.81.21.51.51.2-1.1-1.50.91.21.0
Bone: elastic work0.60.82.2-1.11.20.50.80.80.5-0.4-1.00.30.81.5
Bone: endosteal estimation4.511.013.83.7-3.3-3.4-3.4-3.4-3.63.63.2-3.4-3.12.0
Bone: endosteal perimeter4.711.613.43.6-3.5-3.6-3.7-3.7-3.73.63.3-3.5-2.92.1
Epididymis fat weight0.84.26.12.1-2.3-2.0-1.9-1.9-2.02.02.2-2.5-2.11.0
Delta time in closed arm before/after self-admin1.51.42.2-1.30.71.30.90.91.3-1.5-1.10.81.4-1.2
Delta time in open arm before/after self-admin0.20.20.80.3-0.0-0.2-0.1-0.1-0.20.70.4-0.4-0.90.9
Diff in mean of infusions in LGA sessions0.20.41.00.6-0.6-0.7-0.7-0.7-1.00.50.5-0.1-0.5-0.2
Delay discount exponential model param0.20.30.60.2-0.6-0.7-0.6-0.6-0.70.40.4-0.7-0.30.8
Extinction: sum of active levers before priming0.10.21.20.4-0.80.2-0.2-0.20.0-0.20.1-0.10.1-1.1
Active lever presses in extinction session 61.51.53.31.8-0.9-1.2-1.3-1.3-1.41.31.2-1.0-1.30.0
Bone: final force1.22.03.31.8-1.6-1.4-1.4-1.4-1.51.41.4-1.5-1.1-0.4
Bone: final moment1.11.82.61.6-1.5-1.4-1.4-1.4-1.51.41.3-1.5-1.10.1
Food consumed during 24 hour testing period0.20.30.7-0.20.50.50.60.60.6-0.6-0.60.40.8-0.6
Glucose0.00.00.2-0.4-0.20.2-0.1-0.10.1-0.10.1-0.2-0.1-0.3
Heart weight0.10.21.1-1.0-0.30.30.40.40.2-0.1-0.30.30.50.7
Delay discount hyperbolic model param0.20.30.50.3-0.6-0.6-0.6-0.6-0.70.40.4-0.7-0.30.6
Intermittent access intake day 1-15 change0.31.92.81.6-1.7-1.6-1.7-1.7-1.31.11.0-1.6-0.50.6
Intermittent access intake escalation0.42.13.31.8-1.7-1.7-1.7-1.7-1.41.21.2-1.5-0.70.5
Intermittent access intake escalation 20.30.51.00.8-0.9-1.0-1.0-1.0-0.70.50.5-0.5-0.10.0
Intermitt. access day 1 inactive lever presses0.00.31.2-0.41.10.40.80.80.2-0.1-0.40.50.10.4
Intermitt. access day 15 inactive lever presses0.52.54.41.2-1.6-1.5-1.7-1.7-1.41.81.5-1.1-1.52.1
Intermitt. access escalation Index0.30.91.4-0.90.60.90.90.90.9-1.2-0.91.01.1-1.0
Intermittent access day 1 total infusions0.82.33.71.9-1.3-1.8-1.8-1.8-1.61.61.4-1.0-1.20.8
Intermittent access day 15 total infusions2.25.48.62.9-2.7-2.7-2.8-2.8-2.22.12.1-2.1-1.50.8
Intermittent access terminal intake (last 3 days)2.23.85.82.3-2.2-2.3-2.4-2.4-1.91.81.7-1.6-1.31.0
Intermittent access total infusions3.03.65.52.3-2.1-2.2-2.3-2.3-1.81.81.7-1.4-1.40.8
Intermittent access day 1 locomotion1.01.93.82.0-1.1-1.7-1.5-1.5-1.51.51.3-1.2-1.10.3
Intermittent access day 15 total locomotion1.14.25.62.1-1.9-2.2-2.3-2.3-2.02.11.9-2.4-1.61.6
Intermittent access total locomotion3.33.95.52.4-1.9-2.3-2.3-2.3-2.02.01.9-1.9-1.51.2
Intermittent access standard deviation0.31.72.91.4-1.7-1.3-1.4-1.4-1.21.11.2-1.6-0.80.6
Left kidney weight0.21.64.01.8-2.0-1.0-1.1-1.1-0.90.71.2-1.5-0.6-1.2
Right kidney weight0.10.63.90.9-1.3-0.1-0.3-0.30.1-0.20.3-0.20.2-2.0
Cocaine induced anxiety0.20.61.11.0-0.8-0.7-0.8-0.8-0.80.80.6-0.8-0.50.3
Post-drug Anxiety0.91.02.10.6-1.1-0.7-0.9-0.9-0.91.00.9-1.3-0.91.4
Baseline Anxiety0.30.52.30.0-0.5-0.5-0.5-0.5-0.40.70.7-1.0-0.81.5
Tail length0.21.24.92.2-0.7-0.4-0.4-0.4-0.80.70.90.0-0.9-2.0
Length with tail1.04.410.73.3-2.5-1.9-1.9-1.9-2.01.72.2-1.7-1.9-1.7
Length without tail1.68.413.33.4-3.7-3.1-3.0-3.0-3.02.73.1-2.8-2.50.0
Times rat made contact with spout0.20.20.80.90.1-0.2-0.0-0.0-0.40.50.20.2-0.4-0.6
Lifetime Intake2.93.65.72.4-2.0-2.2-2.3-2.3-1.71.81.7-1.4-1.31.0
Liver weight, left0.50.91.51.0-1.2-0.7-1.0-1.0-1.01.01.2-0.9-1.1-0.2
Liver weight, right1.52.54.61.5-2.2-1.8-1.6-1.6-2.01.61.6-0.9-1.50.5
Locomotor activity0.30.50.9-0.81.00.70.80.80.8-0.5-0.70.60.5-0.0
Locomotor testing distance0.51.31.9-1.11.21.11.21.21.4-1.2-1.20.81.2-0.2
Locomotor testing rearing0.00.10.50.7-0.2-0.4-0.2-0.2-0.10.00.2-0.4-0.1-0.5
Locomotion in novel chamber1.82.45.01.6-1.0-1.6-1.3-1.3-1.71.61.5-2.2-1.91.2
Locomotion in novel chamber post-restriction0.72.25.32.3-1.4-1.6-1.1-1.1-1.51.31.6-1.3-1.8-0.3
Fecal boli incidents, locomotor time 10.10.20.60.7-0.6-0.3-0.4-0.4-0.10.00.10.80.3-0.4
Change in fecal boli incidents, locomotor task0.60.61.0-0.40.90.61.01.00.6-0.6-0.90.80.7-0.7
Time >=10cm from walls, locomotor time 11.41.74.02.0-1.6-1.1-1.0-1.0-1.21.11.4-1.4-1.4-0.7
Bouts of movement, locomotor time 10.40.51.51.2-0.6-0.8-0.9-0.9-0.70.30.3-0.50.0-0.4
Total resting periods, locomotor time 10.60.72.11.5-0.7-1.0-1.0-1.0-0.90.50.4-0.3-0.1-0.5
Rest time, locomotor task time 10.10.21.4-0.10.1-0.0-0.2-0.20.0-0.2-0.41.20.60.3
Distance moved, locomotor task time 10.20.72.1-0.31.00.81.11.10.6-0.6-0.40.5-0.0-1.4
Vertical activity count, locomotor time 10.00.00.2-0.00.00.00.10.1-0.00.00.2-0.4-0.4-0.2
Time >=10cm from walls, locomotor time 20.10.21.30.7-0.00.10.30.30.2-0.20.00.70.0-1.1
Bouts of movement, locomotor time 20.51.63.1-0.91.31.00.90.90.9-1.3-1.51.71.8-1.1
Total resting periods, locomotor time 20.41.73.6-0.81.31.00.90.90.9-1.3-1.61.81.9-1.3
Rest time, locomotor task time 20.10.20.70.5-0.1-0.1-0.2-0.2-0.1-0.2-0.30.80.5-0.8
Distance moved, locomotor task time 20.20.20.80.00.60.50.60.60.4-0.30.00.1-0.4-0.9
Vertical activity count, locomotor time 20.20.61.0-0.91.00.90.60.60.9-0.8-0.70.50.7-0.2
Light reinforcement 10.20.91.70.8-0.6-1.0-0.9-0.9-1.21.30.8-0.3-0.81.3
Light reinforcement 20.71.73.8-2.01.51.21.21.21.0-0.8-1.31.41.21.1
Bone: marrow area4.811.814.63.8-3.4-3.5-3.6-3.6-3.83.73.3-3.5-3.22.1
Bone: maximum diameter9.118.321.84.4-4.7-4.3-4.3-4.3-4.64.54.4-4.5-4.22.0
Bone: maximum force2.24.45.32.3-2.3-2.2-2.2-2.2-2.32.22.2-2.2-1.90.5
Bone: maximum moment2.14.04.82.0-2.2-2.1-2.1-2.1-2.22.22.0-2.2-1.80.9
Mean time between licks in bursts0.42.34.7-2.21.41.61.91.91.5-1.4-1.41.11.30.1
Mean num. licks in bursts0.92.53.61.9-1.3-1.6-1.8-1.8-1.71.81.5-1.1-1.60.6
Cd content in liver2.02.24.4-2.11.21.51.41.41.7-1.6-1.60.71.9-0.3
Co content in liver0.80.93.0-1.70.90.90.90.91.0-0.8-0.90.40.80.8
Cu content in liver1.31.64.2-2.01.51.01.21.21.0-0.8-1.10.80.81.8
Fe content in liver1.72.02.7-1.41.71.41.61.61.3-1.3-1.51.61.3-0.7
K content in liver0.40.41.4-0.20.80.40.50.50.4-0.5-0.71.20.5-0.4
Mg content in liver0.50.61.1-0.91.00.70.80.80.6-0.6-0.71.00.4-0.0
Mn content in liver1.01.12.4-1.61.11.10.90.91.1-1.0-1.11.21.1-0.1
Na content in liver1.41.62.1-0.81.41.31.51.51.2-1.3-1.21.21.0-1.1
Rb content in liver0.20.20.60.6-0.1-0.40.10.1-0.50.60.40.2-0.80.2
Se content in liver24.829.341.4-6.45.85.75.65.65.7-5.6-5.74.85.5-1.9
Sr content in liver0.50.52.9-1.30.20.20.20.20.20.0-0.1-0.6-0.01.7
Zn content in liver7.28.410.0-2.93.22.93.03.03.1-3.0-3.03.02.9-1.7
Bone: minimum diameter5.410.415.84.0-3.7-3.3-3.3-3.3-3.33.23.3-3.5-2.80.6
Time in familiar zone, hab. session 10.10.10.40.1-0.2-0.3-0.1-0.1-0.30.30.2-0.6-0.30.6
Time in novel zone, hab. session 10.70.72.3-0.91.00.70.70.70.8-0.8-0.71.50.7-0.5
Total zone transitions, hab. session 10.10.10.4-0.1-0.0-0.3-0.3-0.3-0.40.50.5-0.1-0.60.5
Total locomotion distance, hab. session 10.30.41.3-0.81.10.70.70.70.5-0.4-0.50.90.1-0.3
Locomotion velocity, hab. session 10.50.71.8-0.81.30.90.90.90.7-0.6-0.71.10.4-0.7
Time in familiar zone, hab. session 20.30.30.7-0.80.40.50.60.60.5-0.5-0.70.20.70.3
Time in novel zone, hab. session 20.10.10.2-0.1-0.3-0.2-0.3-0.3-0.10.20.30.1-0.40.2
Total zone transitions, hab. session 20.40.61.5-1.20.70.80.90.90.8-0.8-0.60.20.5-0.3
Total locomotion distance, hab. session 20.60.81.3-1.20.91.00.90.91.0-1.0-0.80.20.8-0.5
Locomotion velocity, hab. session 20.50.71.0-0.91.00.90.80.81.0-1.0-0.80.30.8-0.8
Novel to familiar place preference ratio0.91.22.21.2-0.8-1.3-1.5-1.5-1.21.11.10.2-0.90.8
Novelty place preference1.11.42.41.2-0.8-1.4-1.6-1.6-1.31.21.20.2-1.01.0
Time in novel zone, NPP test0.81.01.80.9-0.6-1.1-1.3-1.3-1.11.01.00.5-0.80.9
Total zone transitions, NPP test0.60.91.2-0.81.01.01.11.11.0-1.0-0.90.50.7-1.0
Total locomotion distance, NPP test1.21.62.9-1.21.71.41.41.41.3-1.2-1.21.20.9-0.9
Locomotion velocity, NPP test1.01.42.5-0.81.61.41.31.31.2-1.2-1.11.10.9-1.1
Intraocular pressure0.30.61.30.7-0.2-0.7-0.7-0.7-0.81.10.8-0.1-1.10.6
Delta distance traveled before/after self-admin3.43.74.91.5-2.1-2.0-2.0-2.0-1.92.12.0-1.6-1.82.2
Delta ambulatory time before/after self-admin2.54.35.51.7-2.2-2.2-2.1-2.1-2.02.42.1-1.5-2.02.3
Parametrial fat weight0.92.19.8-0.10.91.21.31.31.1-1.5-1.30.61.4-3.1
Pavlov. Cond. lever latency0.70.94.5-0.3-0.5-0.6-0.6-0.6-0.80.90.7-1.1-1.02.1
Pavlov. Cond. magazine entry latency1.62.04.4-1.10.71.51.31.31.5-1.6-1.40.81.7-2.1
Pavlov. Cond. change in total contacts2.52.73.7-1.41.21.81.71.71.8-1.9-1.61.21.8-1.9
Pavlov. Cond. index score1.31.66.6-0.20.51.11.01.01.2-1.3-1.11.01.4-2.6
Pavlov. Cond. latency score1.11.47.40.10.51.00.80.81.1-1.2-0.91.01.2-2.7
Pavlov. Cond. lever contacts1.31.55.0-0.20.91.01.01.01.2-1.3-1.11.31.4-2.2
Pavlov. Cond. magazine entry number0.91.22.30.9-0.3-1.1-1.0-1.0-1.21.31.1-0.5-1.51.4
Pavlov. Cond. intertrial magazine entries0.50.61.71.3-0.5-0.7-0.7-0.7-0.80.80.9-0.5-1.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.72.16.6-0.50.81.41.31.31.5-1.6-1.41.21.7-2.6
Pavlov. Cond. response bias1.82.23.9-1.21.01.61.51.51.6-1.7-1.61.02.0-1.6
Pavlov. Cond. lever latency0.20.20.70.7-0.1-0.4-0.4-0.4-0.30.1-0.10.80.4-0.7
Pavlov. Cond. magazine entry latency1.01.52.2-1.51.01.41.51.51.4-1.4-1.00.60.8-0.9
Pavlov. Cond. change in total contacts0.10.20.5-0.10.30.60.70.70.5-0.4-0.2-0.1-0.1-0.6
Pavlov. Cond. index score0.10.20.4-0.50.20.60.60.60.5-0.4-0.1-0.4-0.2-0.4
Pavlov. Cond. latency score0.10.10.4-0.20.00.40.40.40.3-0.20.1-0.6-0.4-0.3
Pavlov. Cond. lever contacts0.10.20.6-0.70.00.40.40.40.3-0.20.1-0.8-0.40.5
Pavlov. Cond. magazine entry number1.52.03.01.4-1.3-1.6-1.7-1.7-1.61.51.3-0.7-1.01.3
Pavlov. Cond. intertrial magazine entries0.61.43.11.8-1.0-1.2-1.3-1.3-1.31.21.1-0.6-1.1-0.5
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.60.30.70.70.70.6-0.5-0.2-0.3-0.1-0.5
Pavlov. Cond. response bias0.60.81.6-1.20.71.11.21.21.1-1.0-0.70.10.4-0.2
Time in closed arm before self-admin0.10.20.7-0.10.7-0.10.60.60.0-0.2-0.30.90.20.1
Time in closed arm after self-admin1.82.12.9-1.31.71.41.61.61.4-1.5-1.31.51.2-1.1
Time in open arm before self-admin0.00.10.3-0.60.10.1-0.1-0.10.1-0.1-0.1-0.20.20.3
Time in open arm after self-admin1.31.53.20.6-0.9-1.1-1.1-1.1-1.11.31.1-1.8-1.21.7
Bone: periosteal estimation5.513.116.94.1-3.9-3.7-3.7-3.7-3.93.83.6-3.9-3.41.4
Bone: periosteal perimeter4.58.912.53.5-3.3-3.1-3.1-3.1-3.23.03.0-3.2-2.60.7
Bone: post-yield work1.32.33.81.8-2.0-1.4-1.7-1.7-1.61.51.7-1.1-1.3-0.5
Progressive ratio test 1 active lever presses2.13.74.71.8-1.9-2.0-2.2-2.2-1.72.11.8-1.7-1.81.9
Progressive ratio test 1 breakpoint1.93.24.01.7-1.8-1.8-2.0-2.0-1.62.01.7-1.5-1.71.8
Progressive ratio test 1 inactive lever presses0.82.03.51.5-1.5-1.8-1.9-1.9-1.61.31.2-0.1-0.80.9
Progressive ratio test 2 active lever presses5.37.610.43.0-2.8-3.1-3.2-3.2-2.72.82.7-2.2-2.41.9
Progressive ratio test 2 breakpoint6.38.010.93.1-2.9-3.2-3.3-3.3-2.82.82.7-2.3-2.42.0
Progressive ratio test 2 inactive lever presses1.03.35.01.8-1.8-2.2-2.2-2.2-1.71.81.6-1.0-1.31.9
Incentive Sensitization - Responses1.84.98.02.8-2.3-2.8-2.7-2.7-2.52.02.0-1.5-1.50.8
Incentive Sensitization - Breakpoint2.45.48.42.9-2.4-2.8-2.8-2.8-2.52.12.1-1.6-1.60.9
Sum of active levers in priming session hrs 5-60.70.61.1-1.10.90.80.90.90.6-0.6-0.90.60.70.6
Progressive ratio0.10.32.00.4-0.10.20.20.20.5-0.7-0.2-0.20.3-1.4
Food seeking constrained by brief footshock1.21.53.21.8-1.6-1.0-1.2-1.2-0.90.91.0-1.7-0.5-0.6
Seeking ratio, punishment vs. effort0.00.00.20.10.10.10.00.0-0.10.40.00.0-0.00.3
Retroperitoneal fat weight0.10.31.50.7-0.6-0.3-0.3-0.3-0.60.50.4-1.2-0.3-0.3
Reaction time number correct0.72.74.21.8-1.5-1.7-1.4-1.4-1.82.01.7-1.4-1.71.1
Reaction time mean minus median0.00.20.7-0.4-0.7-0.0-0.6-0.60.0-0.30.1-0.70.30.8
Reaction time mean minus median AUC0.00.20.9-0.8-0.10.3-0.1-0.10.3-0.5-0.2-0.30.41.0
Reaction time num false alarms0.50.93.01.7-0.6-0.9-0.7-0.7-1.00.90.9-0.4-0.9-1.0
Reaction time num false alarms AUC0.20.41.91.4-0.2-0.5-0.3-0.3-0.60.50.5-0.2-0.5-1.2
Reaction time trials correct on left0.72.74.21.8-1.5-1.7-1.4-1.4-1.82.01.7-1.4-1.71.1
Reaction time trials on left0.82.64.01.8-1.5-1.7-1.4-1.4-1.82.01.7-1.5-1.71.1
Reaction time mean1.53.47.2-2.71.72.11.61.62.1-2.2-1.91.31.9-0.2
Reaction time mean AUC1.84.38.6-2.91.92.31.81.82.3-2.4-2.11.62.3-0.2
Median of all reaction times2.94.69.0-3.02.22.42.02.02.3-2.3-2.21.72.1-0.3
Reaction time omissions0.20.30.8-0.90.30.70.50.50.8-0.7-0.1-0.6-0.1-0.4
Reaction time false alarm rate0.20.32.00.70.30.10.20.20.0-0.3-0.10.30.1-1.4
Reaction time premature initiation rate1.01.53.01.5-1.5-1.1-1.5-1.5-1.10.81.1-1.7-0.7-0.1
Reaction time premature initiations1.64.87.02.7-2.5-2.1-2.4-2.4-2.22.02.2-2.6-1.80.5
Std. dev. reaction times0.20.82.5-1.60.41.10.50.51.2-1.3-0.80.10.90.2
Reaction time trials completed0.82.64.01.8-1.5-1.7-1.4-1.4-1.82.01.7-1.5-1.71.1
Reaction time trials AUC0.61.93.21.6-1.3-1.5-1.2-1.2-1.61.81.5-1.2-1.50.9
Run reversals in cocaine runway, females0.10.10.8-0.30.0-0.3-0.0-0.0-0.10.1-0.1-0.7-0.00.9
Run reversals in cocaine runway, males0.30.40.8-0.30.40.80.50.50.6-0.7-0.6-0.10.8-0.9
Latency to leave start box in cocaine runway0.60.83.00.7-0.3-0.9-0.8-0.8-0.81.01.2-0.2-1.7-0.1
Latency to leave start box in cocaine runway, F0.30.30.80.60.2-0.5-0.3-0.3-0.50.40.50.9-0.9-0.7
Latency to leave start box in cocaine runway, M1.21.12.60.5-0.8-0.8-1.1-1.1-0.71.11.4-1.3-1.60.7
Std. dev. time between licks in bursts1.73.35.6-2.41.71.92.02.01.9-1.8-1.91.21.9-0.3
Total sessions with >9 infusions0.10.10.20.4-0.5-0.4-0.5-0.50.10.0-0.10.40.4-0.2
Short access day 1 total inactive lever presses0.81.72.80.9-1.1-1.4-1.5-1.5-1.41.41.2-0.6-1.11.7
Short access day 10 total inactive lever presses0.10.51.9-0.30.80.60.60.60.5-0.7-0.61.40.5-0.8
Short access day 1 total infusions0.00.00.20.1-0.1-0.2-0.2-0.20.2-0.1-0.30.20.40.1
Short access day 10 total infusions0.10.10.40.30.0-0.3-0.2-0.20.10.0-0.40.60.70.3
Short access total infusions0.81.12.01.4-1.2-1.4-1.4-1.4-0.81.00.7-0.5-0.40.7
Short access day 1 locomotion0.10.10.3-0.30.20.1-0.1-0.10.5-0.5-0.40.50.5-0.5
Short access day 10 total locomotion0.00.10.20.20.50.10.30.3-0.1-0.1-0.30.00.3-0.3
Short access total locomotion0.10.20.5-0.40.60.20.40.40.5-0.4-0.60.40.7-0.2
One hour access (0.3 mA shock)7.38.612.23.0-3.4-3.3-3.5-3.5-3.02.72.9-2.4-2.31.7
Compulsive drug intake0.10.20.40.1-0.6-0.4-0.4-0.4-0.40.30.60.0-0.6-0.4
One hour access (shock baseline)1.64.16.02.3-2.3-2.2-2.5-2.5-1.91.81.8-2.0-1.31.3
Social response proportion0.60.72.9-0.1-0.6-0.7-0.8-0.8-0.80.90.6-0.9-0.51.7
Social responses1.01.32.20.6-1.2-1.3-1.4-1.4-1.31.20.9-0.6-0.71.5
Social time0.81.32.5-1.30.91.00.90.91.0-1.2-1.21.61.4-0.7
Soleus weight1.03.14.21.2-2.1-1.9-1.7-1.7-1.91.91.8-1.4-1.71.8
Bone: stiffness2.13.87.02.7-2.3-2.0-2.1-2.1-2.11.92.0-1.2-1.6-0.7
Tibialis anterior weight0.62.05.42.3-1.3-1.5-1.2-1.2-1.51.31.40.0-1.4-1.3
Time to tail flick, vehicle, before self-admin0.20.21.3-0.90.40.20.20.20.2-0.1-0.30.00.31.1
Time to tail flick, vehicle, after self-admin0.40.85.81.40.0-0.1-0.3-0.3-0.2-0.4-0.10.20.3-2.4
Time to tail flick, test, before self-admin1.31.52.71.3-1.7-1.2-1.3-1.3-1.11.31.4-0.8-1.40.5
Time to tail flick, test, after self-admin0.80.92.1-0.71.21.00.90.90.9-0.8-0.91.50.8-0.5
Delta time to tail flick, vehicle, before/after SA1.71.87.32.7-0.8-0.9-1.1-1.1-1.00.50.9-0.7-0.8-2.4
Delta time to tail flick, test, before/after SA0.80.91.3-0.91.10.90.90.90.9-1.0-1.11.11.1-0.6
Tibia length0.10.20.70.6-0.3-0.2-0.2-0.2-0.40.40.4-0.8-0.5-0.2
Ambulatory time before self-admin0.20.71.1-0.81.01.01.01.00.9-0.9-0.80.10.6-0.7
Ambulatory time after self-admin1.01.53.10.7-1.0-1.2-1.0-1.0-1.11.41.3-1.3-1.51.8
Bone: tissue strength0.40.41.0-1.00.30.40.40.40.5-0.5-0.70.51.00.4
Total heroin consumption0.91.11.91.4-0.9-1.1-1.3-1.3-1.30.90.9-1.0-0.60.1
Bone: trabecular number5.09.411.02.6-3.3-3.2-3.2-3.2-3.23.33.1-2.7-2.92.9
Bone: trabecular spacing2.53.64.6-1.71.82.02.12.12.0-2.1-1.81.51.7-2.2
Bone: trabecular thickness4.86.77.92.6-2.8-2.7-2.7-2.7-2.72.72.6-2.6-2.41.6
Bone: trabecular tissue density1.62.94.01.9-1.5-1.8-1.7-1.7-1.81.71.9-1.5-2.00.6
Water consumed over 24 hours0.10.31.60.80.40.10.30.3-0.10.1-0.20.60.1-1.3
Number of responses in last shaping day0.10.10.7-0.2-0.3-0.3-0.3-0.3-0.20.1-0.00.00.10.8