Hub : Genes

LOC120100024

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120100024 0.14 0.09 5.1e-05 0.07 0.08 0.06 0.07 3.7e-04 2.2e-04 1.4e-03 4.1e-04
2 NAcc gene expression LOC120100024 0.07 0.04 2.1e-13 0.13 0.12 0.13 0.13 1.4e-14 4.7e-14 1.9e-14 1.4e-14
3 PL gene expression LOC120100024 0.14 0.06 0.0e+00 0.23 0.23 0.22 0.22 9.3e-25 3.9e-25 2.2e-24 2.3e-24
4 BLA gene expression LOC120100024 0.23 0.13 1.5e-08 0.14 0.15 0.13 0.14 4.4e-08 2.6e-08 1.7e-07 1.2e-07
5 Brain gene expression LOC120100024 0.17 0.08 0.0e+00 0.21 0.21 0.22 0.22 1.1e-19 1.1e-19 5.9e-20 5.0e-20
6 IL gene expression LOC120100024 0.28 0.14 1.4e-06 0.2 0.24 0.16 0.09 1.3e-05 2.2e-06 1.3e-04 4.0e-03
7 OFC gene expression LOC120100024 0.31 0.15 1.8e-06 0.19 0.19 0.19 0.21 2.5e-05 2.8e-05 3.1e-05 9.4e-06
8 Adipose gene expression LOC120100024 0.67 0.13 0.0e+00 0.51 0.27 0.53 0.25 4.9e-66 2.3e-30 7.2e-70 5.1e-28
9 LHb gene expression LOC120100024 0.34 0.15 5.1e-08 0.28 0.26 0.29 0.3 2.8e-07 9.3e-07 1.2e-07 7.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density7.212.113.1-3.5-3.5-3.6-3.2-3.6-3.5-3.33.4-3.6
Area under the delay curve0.60.72.1-1.5-0.9-0.8-0.5-0.8-0.3-0.90.80.2
BMI with tail0.10.30.8-0.3-0.4-0.6-0.7-0.4-0.7-0.10.9-0.5
BMI without tail0.61.22.5-1.5-1.0-1.3-1.3-0.6-1.1-0.31.6-0.5
Body weight0.62.35.1-2.3-1.8-1.9-0.9-1.7-1.1-0.91.2-1.3
Weight adjusted by age0.20.20.6-0.3-0.2-0.4-0.3-0.5-0.5-0.50.5-0.8
Bone surface4.68.19.0-3.0-2.9-3.0-2.7-3.0-2.8-2.72.7-2.7
Bone volume5.08.510.2-3.1-3.0-3.1-2.6-3.0-2.8-2.62.8-3.2
Breakpoint value in progressive ratio session0.91.01.9-1.4-1.2-1.2-0.7-1.2-0.7-0.90.7-0.9
Number of licking bursts6.27.29.62.42.92.73.12.82.92.9-2.61.6
Context. condit. distance diff. score2.63.14.4-1.4-1.8-1.7-1.7-1.7-1.9-1.81.8-2.1
Locomotion velocity, session 13.13.34.42.12.11.91.72.01.71.7-1.51.6
Locomotion distance, session 10.40.50.90.90.90.70.80.70.60.5-0.30.5
Locomotion velocity, session 21.11.31.91.41.41.21.21.31.01.1-0.70.8
Locomotion distance, session 21.31.82.91.41.61.31.71.21.41.2-1.20.8
Locomotion velocity, session 30.10.10.50.00.0-0.10.2-0.0-0.0-0.10.1-0.7
Locomotion distance, session 30.10.10.6-0.1-0.0-0.20.1-0.1-0.1-0.10.2-0.8
Stereotopy head waving bouts, day 30.60.71.2-0.6-0.9-0.7-1.1-0.8-0.9-1.00.9-0.5
Stereotopy head waving duration, day 31.21.42.3-1.2-1.3-1.1-1.5-1.1-1.2-1.41.0-0.5
Locomotion velocity, session 71.11.21.5-1.2-1.2-1.2-1.1-1.2-1.0-1.20.9-1.1
Locomotion distance, session 71.11.41.9-1.4-1.4-1.2-1.2-1.3-1.1-1.20.8-1.1
Stereotopy head waving bouts, day 70.00.00.0-0.0-0.2-0.0-0.1-0.0-0.1-0.1-0.0-0.1
Stereotopy head waving duration, day 70.00.00.1-0.2-0.2-0.2-0.2-0.1-0.2-0.30.2-0.1
Locomotion velocity, session 80.10.10.5-0.1-0.4-0.2-0.3-0.3-0.3-0.70.0-0.4
Locomotion distance, session 80.30.41.0-0.1-0.4-0.4-0.4-0.5-0.6-0.80.7-1.0
Degree of sensitization distance0.40.40.9-0.9-1.0-0.6-0.9-0.7-0.5-0.60.10.1
Degree of sensitization stereotypy0.00.00.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.0-0.2
Conditioned locomotion0.30.31.0-0.4-0.7-0.4-0.5-0.6-0.4-0.4-0.0-1.0
Cocaine response after cond. corrected0.81.01.4-1.2-1.2-1.1-1.0-1.0-0.9-0.80.7-0.9
Cocaine response after cond. not corrected1.31.42.7-1.6-1.5-1.3-1.1-1.3-1.0-0.90.9-0.7
Cocaine response before conditioning0.20.21.0-0.8-0.4-0.3-0.2-0.40.1-0.10.21.0
Saline control response2.83.65.5-2.3-2.2-1.9-2.2-1.8-1.8-2.01.7-0.6
Bone: connectivity density5.17.99.0-2.8-2.8-2.8-3.0-3.0-2.9-2.92.8-2.3
Bone: cortical apparent density0.10.10.50.10.10.3-0.30.10.1-0.3-0.40.7
Bone: cortical area2.03.04.2-2.0-1.7-2.0-1.1-1.9-1.5-1.51.7-2.0
Bone: cortical porosity0.30.30.60.60.70.60.30.80.50.5-0.40.6
Bone: cortical porosity0.10.10.20.30.40.30.20.50.30.30.00.2
Bone: cortical thickness0.10.20.7-0.9-0.5-0.60.3-0.5-0.0-0.30.2-0.6
Bone: cortical thickness0.10.10.40.20.20.20.70.20.50.4-0.5-0.3
Bone: cortical tissue density0.10.10.60.30.20.4-0.20.20.2-0.2-0.40.7
Condit. Reinf. active minus inactive responses0.70.81.20.81.00.81.10.71.00.7-0.90.8
Condit. Reinf. active-inactive response ratio1.31.51.81.31.31.31.11.21.21.0-1.11.2
Condit. Reinf. active responses0.20.30.6-0.8-0.5-0.6-0.2-0.7-0.3-0.60.3-0.4
Condit. Reinf. inactive responses2.42.94.0-2.0-1.7-1.9-1.3-1.9-1.5-1.61.5-1.7
Incentive salience index mean0.70.81.50.60.90.81.20.61.10.8-1.00.9
Condit. Reinf. lever presses0.30.41.30.30.50.50.70.30.80.4-0.61.1
Condit. Reinf. active minus inactive responses0.30.30.7-0.6-0.4-0.7-0.2-0.8-0.5-0.50.6-0.7
Condit. Reinf. active-inactive response ratio0.00.00.2-0.00.1-0.20.2-0.2-0.1-0.00.1-0.4
Condit. Reinf. active responses1.92.63.6-1.8-1.4-1.8-1.1-1.9-1.5-1.41.7-1.6
Condit. Reinf. inactive responses1.72.13.1-1.8-1.4-1.6-1.1-1.6-1.3-1.31.5-1.3
Condit. Reinf. lever presses0.10.20.3-0.4-0.3-0.5-0.1-0.6-0.3-0.20.3-0.6
Condit. Reinf. lever reinforcers received1.21.62.3-1.5-1.1-1.5-0.8-1.5-1.2-1.01.4-1.4
Conditioned reinforcement - actives2.02.03.6-1.9-1.7-1.5-1.4-1.2-1.2-1.21.5-1.0
Conditioned reinforcement - inactives4.04.46.1-2.4-2.2-2.1-2.5-1.9-2.1-2.02.3-1.3
Conditioned locomotion1.31.52.6-1.2-1.4-1.1-1.6-1.1-1.3-1.41.3-0.5
Patch foraging indifference point 0 sec0.30.51.10.10.30.51.00.60.90.7-0.71.0
Patch foraging indifference point AUC0.30.41.4-1.2-0.5-0.6-0.5-0.4-0.1-0.30.40.9
Delay disc. indifference point, 0s delay0.91.02.3-1.5-1.2-1.2-0.8-0.9-0.7-0.71.0-0.6
Delay disc. indifference point, 16s delay2.22.34.2-2.0-1.6-1.5-1.3-1.7-1.2-1.81.4-0.6
Delay disc. indifference point, 2s delay1.01.12.1-1.3-1.1-1.0-1.0-1.2-0.8-1.40.9-0.3
Delay disc. indifference point, 24s delay0.70.71.9-1.4-0.9-0.6-0.6-0.8-0.1-0.90.51.0
Delay disc. indifference point, 4s delay0.70.82.2-1.5-0.9-1.0-0.6-1.1-0.4-1.00.7-0.1
Delay disc. indifference point, 8s delay0.20.31.7-0.50.00.10.20.10.5-0.0-0.11.3
Indifference point function ln k0.20.21.60.5-0.10.00.2-0.1-0.3-0.3-0.1-1.3
Indifference point function log k0.20.21.60.5-0.10.00.2-0.1-0.3-0.3-0.1-1.3
Patch foraging total patch changes 0 sec0.30.40.9-0.00.30.40.90.60.80.6-0.51.0
Patch foraging total patch changes 12 sec0.30.42.3-0.20.30.30.30.50.70.5-0.41.5
Patch foraging total patch changes 18 sec0.10.10.5-0.7-0.2-0.2-0.0-0.00.2-0.0-0.10.6
Patch foraging total patch changes 24 sec0.30.30.7-0.30.20.20.80.30.80.8-0.40.8
Patch foraging total patch changes 6 sec0.40.53.0-0.50.20.30.50.40.90.4-0.41.7
Patch foraging time to switch 0 sec2.74.16.32.52.22.22.12.01.91.9-2.10.9
Patch foraging water rate 0 sec0.60.91.4-1.1-1.1-1.2-1.0-0.8-1.1-0.51.2-0.5
Patch foraging water rate 12 sec0.00.00.1-0.3-0.3-0.20.1-0.10.0-0.00.1-0.1
Patch foraging water rate 18 sec0.20.20.4-0.6-0.6-0.6-0.3-0.4-0.4-0.10.6-0.5
Patch foraging water rate 24 sec1.31.83.1-1.8-1.6-1.6-1.0-1.4-1.2-1.21.1-1.0
Patch foraging water rate 6 sec0.10.10.2-0.2-0.4-0.3-0.4-0.2-0.4-0.10.5-0.3
Seeking ratio, delayed vs. immediate footshock0.10.10.30.50.30.40.30.50.30.3-0.4-0.0
Distance traveled before self-admin0.10.10.3-0.20.0-0.2-0.3-0.0-0.20.10.50.2
Distance traveled after self-admin2.73.04.7-1.6-1.5-1.7-2.2-1.5-1.9-1.82.0-1.4
Extensor digitorum longus weight0.41.52.3-1.5-1.4-1.3-1.3-1.4-1.0-1.41.1-0.6
Bone: elastic displacement2.12.44.72.21.91.71.11.91.11.4-0.91.2
Bone: elastic work0.60.72.01.41.10.90.21.20.20.7-0.10.7
Bone: endosteal estimation4.29.210.0-3.0-3.2-3.1-3.0-3.1-3.1-2.83.0-3.0
Bone: endosteal perimeter2.75.69.1-2.0-2.2-2.4-2.1-2.3-2.5-2.12.6-3.0
Epididymis fat weight0.00.10.3-0.20.1-0.10.5-0.20.30.5-0.1-0.1
Delta time in closed arm before/after self-admin8.38.011.52.93.02.73.32.92.83.4-2.51.6
Delta time in open arm before/after self-admin5.14.96.9-2.1-2.4-2.1-2.4-2.5-2.3-2.61.9-1.4
Diff in mean of infusions in LGA sessions0.30.41.00.70.70.40.80.50.41.00.1-0.3
Delay discount exponential model param0.50.61.91.40.80.70.40.80.20.9-0.6-0.4
Extinction: sum of active levers before priming0.00.00.1-0.3-0.3-0.20.1-0.1-0.0-0.00.0-0.1
Active lever presses in extinction session 62.12.12.6-1.6-1.4-1.5-1.4-1.5-1.3-1.41.3-1.4
Bone: final force0.30.50.9-1.0-0.8-0.9-0.3-0.8-0.5-0.70.6-0.7
Bone: final moment0.30.50.8-0.9-0.8-0.8-0.4-0.8-0.5-0.70.6-0.6
Food consumed during 24 hour testing period1.21.52.31.01.41.11.51.21.41.4-1.20.7
Glucose0.40.50.90.80.70.70.90.80.70.9-0.60.3
Heart weight0.60.81.10.80.90.91.00.90.90.9-0.81.0
Delay discount hyperbolic model param0.60.71.91.40.80.80.50.90.31.0-0.7-0.3
Intermittent access intake day 1-15 change0.60.61.1-0.7-0.6-0.8-0.7-0.4-0.9-0.61.0-0.9
Intermittent access intake escalation0.20.20.5-0.4-0.4-0.5-0.4-0.2-0.5-0.40.7-0.6
Intermittent access intake escalation 20.10.10.20.40.20.10.10.3-0.10.10.1-0.4
Intermitt. access day 1 inactive lever presses1.31.43.1-1.1-0.8-1.2-1.5-0.8-1.4-0.91.8-0.9
Intermitt. access day 15 inactive lever presses5.35.88.7-2.6-2.4-2.4-2.8-2.1-2.5-2.03.0-1.7
Intermitt. access escalation Index0.30.30.4-0.6-0.6-0.6-0.7-0.5-0.4-0.50.40.4
Intermittent access day 1 total infusions1.51.82.6-1.5-1.6-1.3-1.3-1.5-1.2-1.51.0-0.9
Intermittent access day 15 total infusions2.32.63.6-1.9-1.9-1.7-1.6-1.6-1.5-1.61.6-1.0
Intermittent access terminal intake (last 3 days)1.51.62.3-1.4-1.5-1.3-1.4-1.1-1.3-1.21.3-0.7
Intermittent access total infusions1.11.31.8-1.2-1.3-1.1-1.2-1.1-1.1-1.11.0-0.8
Intermittent access day 1 locomotion0.70.71.2-1.0-1.1-0.9-0.7-1.0-0.7-0.90.8-0.5
Intermittent access day 15 total locomotion1.11.21.8-0.9-1.3-1.0-1.2-1.0-1.2-1.20.8-0.9
Intermittent access total locomotion0.30.30.6-0.5-0.7-0.5-0.6-0.5-0.6-0.70.4-0.3
Intermittent access standard deviation0.40.41.0-0.6-0.6-0.6-0.7-0.3-0.7-0.41.0-0.6
Left kidney weight0.20.61.7-0.10.50.21.20.70.91.3-0.50.3
Right kidney weight0.82.23.70.41.21.11.91.21.91.9-1.71.5
Cocaine induced anxiety0.00.00.1-0.2-0.0-0.2-0.1-0.0-0.20.20.3-0.0
Post-drug Anxiety0.60.71.1-0.9-0.8-0.9-1.1-0.8-1.0-0.80.9-0.3
Baseline Anxiety0.20.20.4-0.4-0.5-0.4-0.6-0.5-0.5-0.60.3-0.3
Tail length1.34.111.0-3.3-2.4-2.4-1.7-1.9-1.4-1.41.7-0.9
Length with tail0.93.39.8-3.1-2.2-2.2-0.8-2.1-0.9-1.30.8-1.1
Length without tail0.30.61.7-1.0-0.9-0.70.2-1.3-0.1-0.9-0.3-0.9
Times rat made contact with spout0.50.51.2-1.1-0.6-0.9-0.7-0.6-0.6-0.50.9-0.5
Lifetime Intake1.01.11.8-1.2-1.3-1.0-1.1-1.0-0.9-1.10.8-0.6
Liver weight, left0.30.62.6-0.7-0.6-0.70.3-0.7-0.3-0.20.5-1.6
Liver weight, right0.10.20.9-0.9-0.5-0.60.1-0.50.00.20.30.0
Locomotor activity0.91.51.81.31.31.31.31.31.31.1-1.20.8
Locomotor testing distance1.52.53.01.71.71.71.71.71.71.4-1.51.1
Locomotor testing rearing0.10.10.30.40.30.30.50.30.30.2-0.4-0.3
Locomotion in novel chamber0.50.63.30.4-0.3-0.4-0.4-0.5-0.9-0.70.3-1.8
Locomotion in novel chamber post-restriction1.41.73.7-1.2-1.3-1.4-0.8-1.2-1.2-1.01.3-1.9
Fecal boli incidents, locomotor time 10.60.71.4-0.8-0.9-0.8-1.2-0.7-0.8-1.00.40.3
Change in fecal boli incidents, locomotor task0.10.10.10.10.20.30.30.20.30.2-0.30.3
Time >=10cm from walls, locomotor time 12.72.74.1-1.8-1.7-1.7-1.2-2.0-1.5-1.61.5-1.6
Bouts of movement, locomotor time 10.40.40.70.50.40.60.80.80.70.7-0.7-0.1
Total resting periods, locomotor time 10.00.00.1-0.1-0.10.10.30.20.30.1-0.3-0.2
Rest time, locomotor task time 10.10.20.4-0.3-0.5-0.2-0.6-0.3-0.3-0.70.0-0.1
Distance moved, locomotor task time 10.10.10.4-0.20.3-0.10.40.10.20.60.10.2
Vertical activity count, locomotor time 10.30.30.70.60.70.50.80.50.50.8-0.30.0
Time >=10cm from walls, locomotor time 21.01.02.5-1.6-1.0-1.2-0.8-0.9-0.8-0.51.3-0.1
Bouts of movement, locomotor time 21.51.63.11.01.01.21.11.11.41.1-1.61.8
Total resting periods, locomotor time 22.02.23.61.21.11.41.41.31.61.1-1.91.9
Rest time, locomotor task time 21.51.73.91.21.11.51.51.01.60.6-2.00.7
Distance moved, locomotor task time 20.81.03.1-1.1-0.6-1.2-0.8-0.6-1.00.11.8-0.6
Vertical activity count, locomotor time 20.20.20.6-0.5-0.2-0.4-0.5-0.2-0.40.20.80.5
Light reinforcement 10.10.20.9-0.3-0.3-0.5-0.4-0.3-0.4-0.10.5-0.9
Light reinforcement 20.81.01.51.21.21.10.61.00.80.8-0.91.2
Bone: marrow area4.69.910.7-3.1-3.3-3.3-3.1-3.2-3.3-2.93.1-3.1
Bone: maximum diameter6.812.618.2-3.3-3.4-3.6-3.1-3.5-3.6-3.33.7-4.3
Bone: maximum force1.52.63.4-1.9-1.7-1.8-1.3-1.6-1.6-1.51.6-1.5
Bone: maximum moment1.32.22.9-1.7-1.6-1.7-1.2-1.5-1.4-1.41.5-1.3
Mean time between licks in bursts2.13.03.81.91.91.81.61.81.61.7-1.41.6
Mean num. licks in bursts7.28.611.2-2.9-3.1-3.0-3.4-2.9-3.1-3.02.9-1.7
Cd content in liver0.20.20.90.10.40.30.40.60.40.6-0.11.0
Co content in liver0.20.20.6-0.1-0.1-0.1-0.7-0.3-0.5-0.60.40.5
Cu content in liver1.11.32.01.01.21.21.01.01.21.1-1.21.4
Fe content in liver7.28.610.13.13.23.03.03.02.93.0-2.72.5
K content in liver0.20.20.30.50.30.50.30.40.40.4-0.60.5
Mg content in liver0.60.71.00.70.80.80.70.80.81.0-0.90.8
Mn content in liver1.92.12.61.31.41.51.51.41.61.3-1.51.6
Na content in liver1.51.52.61.31.41.21.31.31.21.6-1.00.8
Rb content in liver0.10.10.20.10.20.10.50.10.20.3-0.2-0.3
Se content in liver22.327.430.45.15.55.35.05.45.35.1-4.95.5
Sr content in liver0.90.81.2-0.5-0.8-0.7-1.1-0.9-1.0-1.10.9-0.8
Zn content in liver9.610.712.23.53.43.43.03.23.23.2-3.13.2
Bone: minimum diameter3.56.68.3-2.7-2.5-2.8-2.1-2.6-2.5-2.32.7-2.9
Time in familiar zone, hab. session 10.20.20.4-0.5-0.5-0.3-0.6-0.4-0.4-0.40.2-0.1
Time in novel zone, hab. session 11.41.41.71.31.31.21.31.21.21.1-1.20.7
Total zone transitions, hab. session 10.10.10.70.10.1-0.10.1-0.0-0.0-0.1-0.1-0.8
Total locomotion distance, hab. session 11.01.41.91.41.31.21.31.21.11.2-1.3-0.1
Locomotion velocity, hab. session 11.01.42.01.41.31.21.21.21.11.2-1.20.1
Time in familiar zone, hab. session 20.10.10.60.20.20.30.00.50.30.3-0.30.8
Time in novel zone, hab. session 20.10.10.2-0.1-0.2-0.1-0.1-0.4-0.2-0.30.0-0.4
Total zone transitions, hab. session 20.81.11.81.01.21.01.31.01.11.1-0.80.7
Total locomotion distance, hab. session 22.22.93.92.02.01.72.01.81.71.8-1.40.8
Locomotion velocity, hab. session 22.33.24.22.02.01.82.11.91.81.9-1.50.8
Novel to familiar place preference ratio1.11.11.4-1.2-1.1-1.1-1.1-1.2-1.0-1.10.9-0.9
Novelty place preference1.21.21.4-1.2-1.2-1.1-1.2-1.2-1.0-1.10.9-1.0
Time in novel zone, NPP test0.30.30.5-0.6-0.6-0.5-0.6-0.7-0.5-0.60.3-0.7
Total zone transitions, NPP test1.31.82.81.31.41.31.71.21.51.3-1.30.9
Total locomotion distance, NPP test1.41.92.51.51.61.41.61.41.41.6-1.10.7
Locomotion velocity, NPP test0.60.91.30.91.10.91.21.01.01.1-0.60.6
Intraocular pressure0.10.10.60.10.1-0.00.4-0.20.1-0.2-0.3-0.8
Delta distance traveled before/after self-admin2.83.13.5-1.6-1.8-1.7-1.9-1.7-1.9-1.91.6-1.7
Delta ambulatory time before/after self-admin6.16.77.5-2.5-2.7-2.6-2.7-2.5-2.7-2.72.5-2.3
Parametrial fat weight0.20.31.0-1.0-0.7-0.8-0.3-0.5-0.3-0.40.4-0.3
Pavlov. Cond. lever latency0.10.10.5-0.1-0.4-0.2-0.4-0.2-0.3-0.40.0-0.7
Pavlov. Cond. magazine entry latency2.63.34.51.91.81.82.11.61.91.7-1.81.6
Pavlov. Cond. change in total contacts1.82.02.61.31.61.31.61.31.51.4-1.01.4
Pavlov. Cond. index score1.11.42.41.01.21.01.60.91.31.2-1.01.2
Pavlov. Cond. latency score0.60.71.50.60.80.71.20.61.00.9-0.70.9
Pavlov. Cond. lever contacts0.50.61.10.50.80.61.00.60.90.7-0.51.0
Pavlov. Cond. magazine entry number2.12.63.7-1.7-1.7-1.6-1.9-1.5-1.7-1.71.5-1.3
Pavlov. Cond. intertrial magazine entries1.41.72.6-1.6-1.4-1.4-1.2-1.4-1.2-1.11.1-1.1
Pavlov. Cond. lever-magazine prob. diff.1.82.23.51.31.51.41.91.21.61.5-1.41.5
Pavlov. Cond. response bias3.34.05.12.02.12.02.31.92.12.0-1.91.8
Pavlov. Cond. lever latency0.10.10.30.50.40.50.30.50.30.2-0.40.1
Pavlov. Cond. magazine entry latency0.81.01.40.91.21.01.20.81.10.9-1.00.6
Pavlov. Cond. change in total contacts0.20.30.7-0.8-0.5-0.6-0.4-0.6-0.4-0.40.4-0.1
Pavlov. Cond. index score0.00.00.1-0.4-0.1-0.20.2-0.30.1-0.00.0-0.2
Pavlov. Cond. latency score0.10.10.2-0.4-0.2-0.40.1-0.4-0.1-0.20.2-0.4
Pavlov. Cond. lever contacts0.10.20.3-0.6-0.4-0.4-0.3-0.5-0.3-0.30.3-0.2
Pavlov. Cond. magazine entry number1.41.72.3-1.1-1.4-1.3-1.5-1.1-1.5-1.31.5-1.1
Pavlov. Cond. intertrial magazine entries0.40.61.2-0.9-0.8-0.8-0.4-0.9-0.5-0.60.5-1.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.20.1-0.00.4-0.10.30.2-0.2-0.1
Pavlov. Cond. response bias0.20.30.50.20.50.40.70.30.60.6-0.60.5
Time in closed arm before self-admin0.40.51.0-0.8-0.8-0.6-1.0-0.7-0.7-0.90.5-0.1
Time in closed arm after self-admin1.51.51.90.91.21.11.31.21.41.4-1.21.2
Time in open arm before self-admin1.51.62.51.41.51.21.41.51.21.6-0.80.6
Time in open arm after self-admin1.31.42.3-0.9-1.0-1.1-1.0-1.4-1.2-1.41.0-1.5
Bone: periosteal estimation4.59.310.8-3.1-3.1-3.2-2.7-3.1-3.0-2.83.0-3.3
Bone: periosteal perimeter3.45.68.0-2.3-2.3-2.5-1.9-2.4-2.3-2.12.5-2.8
Bone: post-yield work1.82.44.7-2.2-1.8-1.8-1.0-1.7-1.2-1.41.2-1.3
Progressive ratio test 1 active lever presses3.73.95.3-2.1-2.3-1.9-2.1-1.9-1.9-2.11.8-1.3
Progressive ratio test 1 breakpoint3.23.34.5-1.9-2.1-1.8-2.0-1.8-1.8-1.91.7-1.2
Progressive ratio test 1 inactive lever presses4.54.96.7-2.6-2.5-2.2-2.5-2.1-2.1-2.12.2-1.3
Progressive ratio test 2 active lever presses2.83.04.3-1.7-2.1-1.7-1.8-1.7-1.7-1.71.5-1.7
Progressive ratio test 2 breakpoint3.43.84.6-1.9-2.1-1.9-1.9-1.9-2.0-1.91.8-2.1
Progressive ratio test 2 inactive lever presses3.54.15.6-2.0-2.2-1.9-2.4-1.8-2.1-2.02.1-1.6
Incentive Sensitization - Responses1.11.11.8-0.9-1.0-1.1-0.9-1.0-1.1-0.90.9-1.4
Incentive Sensitization - Breakpoint1.31.32.0-1.0-1.1-1.2-1.0-1.1-1.2-1.01.0-1.4
Sum of active levers in priming session hrs 5-60.10.10.4-0.3-0.1-0.2-0.6-0.1-0.3-0.30.5-0.2
Progressive ratio0.20.30.60.50.50.30.70.60.50.7-0.30.0
Food seeking constrained by brief footshock0.20.20.70.40.20.30.80.40.40.70.1-0.5
Seeking ratio, punishment vs. effort0.00.00.1-0.0-0.00.20.3-0.10.20.1-0.10.0
Retroperitoneal fat weight0.00.10.4-0.2-0.0-0.30.2-0.2-0.10.30.1-0.6
Reaction time number correct2.43.54.4-1.9-2.0-1.8-2.0-1.9-1.8-2.11.7-1.7
Reaction time mean minus median0.10.10.50.70.20.50.30.30.20.1-0.5-0.1
Reaction time mean minus median AUC0.10.10.30.50.10.30.20.20.10.0-0.4-0.1
Reaction time num false alarms0.10.20.7-0.30.2-0.30.40.10.00.50.6-0.8
Reaction time num false alarms AUC0.30.51.10.30.90.31.10.70.71.00.0-0.4
Reaction time trials correct on left2.43.54.4-1.9-2.0-1.8-2.0-1.9-1.8-2.11.7-1.7
Reaction time trials on left2.43.44.2-1.9-2.0-1.7-1.9-1.9-1.7-2.11.7-1.7
Reaction time mean2.83.95.62.41.92.21.81.81.91.7-2.31.8
Reaction time mean AUC3.34.56.42.51.92.41.82.02.01.8-2.42.0
Median of all reaction times3.54.96.82.62.12.51.92.02.12.0-2.42.1
Reaction time omissions0.10.20.50.60.60.40.70.40.30.4-0.1-0.3
Reaction time false alarm rate0.91.32.50.91.40.81.51.31.11.6-0.50.1
Reaction time premature initiation rate0.10.20.8-0.6-0.4-0.4-0.0-0.4-0.2-0.30.1-0.9
Reaction time premature initiations1.62.33.9-1.7-1.6-1.5-1.1-1.6-1.2-1.51.1-2.0
Std. dev. reaction times0.71.01.71.30.91.21.00.90.90.9-1.10.6
Reaction time trials completed2.43.44.2-1.9-2.0-1.7-1.9-1.9-1.7-2.11.7-1.7
Reaction time trials AUC1.82.63.4-1.7-1.7-1.5-1.7-1.7-1.5-1.81.5-1.4
Run reversals in cocaine runway, females0.10.10.30.50.20.30.10.20.10.1-0.3-0.2
Run reversals in cocaine runway, males1.51.52.41.11.21.21.61.11.31.1-1.40.8
Latency to leave start box in cocaine runway2.02.23.8-1.0-1.3-1.5-1.3-1.2-1.7-1.21.9-2.0
Latency to leave start box in cocaine runway, F0.90.92.6-0.6-0.6-1.0-0.9-0.5-1.2-0.41.6-1.2
Latency to leave start box in cocaine runway, M0.70.71.8-0.6-0.8-0.7-0.4-1.0-0.7-0.90.6-1.3
Std. dev. time between licks in bursts4.55.46.42.52.52.42.22.52.22.4-2.12.1
Total sessions with >9 infusions0.10.10.3-0.4-0.6-0.3-0.2-0.2-0.2-0.3-0.10.1
Short access day 1 total inactive lever presses3.64.16.8-1.8-2.0-1.8-2.6-1.9-2.1-2.22.2-1.4
Short access day 10 total inactive lever presses1.41.63.1-1.6-1.1-1.1-1.8-1.0-1.1-1.21.70.4
Short access day 1 total infusions0.60.61.3-1.0-1.2-0.5-0.9-0.8-0.4-1.10.10.4
Short access day 10 total infusions0.10.10.8-0.3-0.40.1-0.20.20.20.1-0.30.9
Short access total infusions0.70.81.7-1.2-1.3-0.8-0.9-1.0-0.7-1.10.5-0.3
Short access day 1 locomotion0.10.10.6-0.2-0.20.0-0.00.10.1-0.1-0.20.8
Short access day 10 total locomotion0.10.10.20.40.30.30.20.40.20.2-0.10.3
Short access total locomotion0.10.10.50.30.10.40.30.30.40.2-0.50.7
One hour access (0.3 mA shock)3.94.65.3-2.3-2.3-2.2-1.9-2.0-2.1-2.02.3-2.1
Compulsive drug intake4.04.05.4-2.3-2.1-2.1-2.0-2.2-1.8-2.02.0-1.2
One hour access (shock baseline)0.00.00.10.20.10.10.30.40.00.3-0.0-0.3
Social response proportion0.30.31.20.2-0.6-0.2-0.7-0.6-0.7-1.1-0.1-0.5
Social responses0.91.11.9-0.9-1.2-0.9-1.4-1.1-1.1-1.40.8-0.4
Social time0.50.72.50.4-0.20.70.40.20.80.0-1.51.6
Soleus weight0.92.73.6-1.4-1.6-1.6-1.9-1.5-1.8-1.61.8-1.5
Bone: stiffness1.32.13.6-1.9-1.6-1.7-1.1-1.5-1.2-1.11.3-1.2
Tibialis anterior weight1.34.46.0-2.4-2.4-2.1-2.3-2.2-1.9-2.31.8-1.0
Time to tail flick, vehicle, before self-admin0.10.10.40.50.30.30.10.10.20.0-0.60.5
Time to tail flick, vehicle, after self-admin0.10.10.3-0.5-0.3-0.30.1-0.20.0-0.1-0.1-0.2
Time to tail flick, test, before self-admin3.13.14.2-1.6-1.8-1.8-1.6-1.9-1.7-2.01.4-1.8
Time to tail flick, test, after self-admin0.50.61.2-1.1-0.6-0.8-0.9-0.6-0.6-0.70.90.3
Delta time to tail flick, vehicle, before/after SA1.01.01.7-1.3-1.1-1.1-0.4-0.9-0.7-0.80.9-1.3
Delta time to tail flick, test, before/after SA0.20.10.6-0.10.30.10.20.40.30.60.10.8
Tibia length0.00.10.2-0.5-0.4-0.30.2-0.10.00.20.0-0.4
Ambulatory time before self-admin0.30.30.70.60.60.50.40.60.40.7-0.30.8
Ambulatory time after self-admin3.53.85.4-1.6-1.8-1.9-2.3-1.8-2.2-2.12.2-1.7
Bone: tissue strength0.40.31.60.40.40.50.10.50.40.4-0.61.3
Total heroin consumption1.21.42.5-1.6-1.2-1.4-1.2-1.2-1.0-1.21.0-0.7
Bone: trabecular number4.87.68.8-3.0-2.8-2.9-2.7-2.8-2.7-2.62.8-2.5
Bone: trabecular spacing1.21.62.41.01.11.21.31.11.41.2-1.41.5
Bone: trabecular thickness2.42.94.4-1.8-1.7-1.8-1.5-1.7-1.6-1.61.5-2.1
Bone: trabecular tissue density3.34.66.0-2.0-2.2-2.2-2.1-2.0-2.3-2.11.9-2.5
Water consumed over 24 hours0.10.20.3-0.10.40.20.40.50.50.5-0.30.5
Number of responses in last shaping day2.82.94.2-1.9-2.1-1.7-1.9-1.6-1.7-1.71.6-1.2