Hub : Genes

LOC120099916

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120099916 0.17 0.08 8.2e-10 0.12 0.17 0.18 0.16 4.7e-07 2.1e-09 1.0e-09 6.4e-09
2 IC gene expression LOC120099916 0.11 0.08 9.3e-04 0.01 0.04 0.04 0.02 7.7e-02 1.3e-02 7.0e-03 3.3e-02
3 Adipose gene expression LOC120099916 0.05 0.03 1.6e-03 0.03 0.01 0.02 0.03 1.2e-04 2.2e-02 1.6e-03 1.5e-04
4 PL gene expression LOC120099916 0.21 0.1 0.0e+00 0.17 0.21 0.2 0.21 2.8e-18 1.6e-22 2.1e-21 2.5e-22
5 OFC gene expression LOC120099916 0.27 0.13 3.2e-04 0.08 0.08 0.11 0.09 6.4e-03 6.1e-03 1.4e-03 3.5e-03
6 IL gene expression LOC120099916 0.37 0.14 9.4e-06 0.19 0.13 0.13 0.17 2.4e-05 5.5e-04 5.5e-04 5.6e-05
7 NAcc gene expression LOC120099916 0.06 0.04 3.9e-10 0.06 0.07 0.07 0.07 2.0e-09 1.8e-10 3.5e-10 2.7e-10
8 Brain gene expression LOC120099916 0.08 0.05 6.3e-06 0.04 0.05 0.04 0.04 9.5e-05 2.2e-05 1.7e-04 9.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.41.71.30.3-1.0-0.60.4-0.0-0.3-0.1
Area under the delay curve0.10.20.6-0.1-0.60.80.2-0.2-0.40.20.3
BMI with tail1.96.710.63.33.2-3.1-2.52.42.1-2.0-1.8
BMI without tail1.47.517.03.83.4-4.1-2.22.12.0-1.6-1.1
Body weight0.93.910.72.92.2-3.3-1.61.41.0-1.1-0.7
Weight adjusted by age0.20.52.5-0.10.9-1.6-0.10.10.5-0.1-0.4
Bone surface0.71.32.71.61.0-0.8-1.31.30.8-1.2-1.0
Bone volume0.71.53.82.01.1-1.2-1.31.20.8-1.1-0.8
Breakpoint value in progressive ratio session1.11.93.7-1.9-1.20.61.6-1.6-1.21.51.2
Number of licking bursts0.51.47.5-1.5-1.12.70.3-0.3-0.0-0.1-0.3
Context. condit. distance diff. score0.30.40.7-0.8-0.4-0.20.8-0.8-0.40.70.6
Locomotion velocity, session 10.10.20.40.5-0.40.6-0.40.2-0.2-0.4-0.3
Locomotion distance, session 10.30.31.90.5-0.1-1.4-0.0-0.3-0.50.20.2
Locomotion velocity, session 20.20.20.70.0-0.80.8-0.0-0.0-0.5-0.10.0
Locomotion distance, session 20.60.92.61.60.6-0.6-1.10.90.3-0.9-0.7
Locomotion velocity, session 30.10.10.20.50.3-0.5-0.20.10.1-0.2-0.2
Locomotion distance, session 31.41.72.40.81.40.8-1.31.21.5-1.4-1.5
Stereotopy head waving bouts, day 31.11.41.9-1.2-1.3-0.01.2-1.2-1.41.21.2
Stereotopy head waving duration, day 31.01.31.9-0.8-1.2-0.91.1-1.1-1.41.21.2
Locomotion velocity, session 72.62.84.51.42.10.1-1.61.82.1-1.6-1.8
Locomotion distance, session 71.11.42.10.60.71.1-1.21.51.1-1.4-1.4
Stereotopy head waving bouts, day 70.30.40.6-0.1-0.5-0.70.6-0.8-0.70.60.6
Stereotopy head waving duration, day 70.50.63.10.90.8-1.8-0.20.00.2-0.0-0.0
Locomotion velocity, session 80.10.10.30.1-0.50.40.2-0.4-0.50.20.2
Locomotion distance, session 80.00.00.10.3-0.1-0.3-0.2-0.0-0.1-0.1-0.1
Degree of sensitization distance1.21.32.4-0.6-1.5-0.41.1-0.9-1.51.21.4
Degree of sensitization stereotypy0.40.41.21.10.7-0.8-0.60.40.4-0.5-0.4
Conditioned locomotion0.40.41.5-0.50.31.2-0.30.50.6-0.5-0.8
Cocaine response after cond. corrected0.10.10.4-0.2-0.40.70.10.1-0.1-0.0-0.0
Cocaine response after cond. not corrected0.20.30.50.50.60.2-0.60.70.6-0.6-0.5
Cocaine response before conditioning2.53.05.12.02.3-0.5-1.81.71.9-1.7-1.5
Saline control response0.30.50.8-0.6-0.2-0.40.8-0.8-0.50.80.9
Bone: connectivity density0.20.40.80.80.7-0.9-0.60.50.3-0.4-0.4
Bone: cortical apparent density0.20.31.6-0.6-0.51.30.3-0.3-0.00.20.2
Bone: cortical area1.62.56.42.51.4-1.1-1.81.71.1-1.5-1.1
Bone: cortical porosity0.30.31.70.30.8-1.3-0.00.20.30.10.0
Bone: cortical porosity0.30.31.5-0.30.4-1.20.5-0.3-0.10.60.5
Bone: cortical thickness0.50.83.41.90.1-0.0-1.01.00.1-0.8-0.3
Bone: cortical thickness0.40.41.31.2-0.51.1-0.50.3-0.4-0.40.1
Bone: cortical tissue density0.20.31.5-0.7-0.51.20.4-0.3-0.00.20.2
Condit. Reinf. active minus inactive responses0.40.50.6-0.8-0.4-0.50.8-0.6-0.70.80.8
Condit. Reinf. active-inactive response ratio0.20.31.0-0.60.3-1.00.4-0.30.00.50.4
Condit. Reinf. active responses0.40.51.0-0.6-0.8-0.30.7-0.5-1.00.80.7
Condit. Reinf. inactive responses0.20.30.9-0.1-0.90.20.3-0.3-1.00.40.4
Incentive salience index mean0.10.20.5-0.00.7-0.3-0.30.50.6-0.3-0.4
Condit. Reinf. lever presses0.50.71.30.11.10.2-0.70.81.2-0.8-1.0
Condit. Reinf. active minus inactive responses0.81.34.7-0.3-0.3-2.20.9-1.1-0.81.21.2
Condit. Reinf. active-inactive response ratio1.01.62.5-0.8-0.5-1.61.4-1.4-1.01.51.4
Condit. Reinf. active responses0.40.63.40.00.3-1.90.4-0.5-0.20.60.6
Condit. Reinf. inactive responses1.11.62.21.31.5-0.4-1.41.31.4-1.3-1.3
Condit. Reinf. lever presses0.50.74.60.60.8-2.1-0.1-0.10.10.10.1
Condit. Reinf. lever reinforcers received0.50.73.1-0.4-0.0-1.80.7-0.8-0.50.80.8
Conditioned reinforcement - actives0.00.10.20.2-0.30.30.1-0.4-0.10.20.4
Conditioned reinforcement - inactives0.10.10.6-0.4-0.50.80.2-0.3-0.00.00.2
Conditioned locomotion0.00.00.2-0.1-0.10.40.1-0.10.2-0.00.0
Patch foraging indifference point 0 sec0.61.62.9-0.2-0.8-1.71.2-1.4-1.31.41.6
Patch foraging indifference point AUC0.10.31.11.10.4-0.6-0.60.30.3-0.5-0.2
Delay disc. indifference point, 0s delay2.22.43.31.81.31.0-1.81.51.6-1.8-1.5
Delay disc. indifference point, 16s delay3.24.56.1-2.5-2.41.52.2-2.2-2.12.01.9
Delay disc. indifference point, 2s delay3.23.66.72.62.0-0.7-2.12.01.7-1.9-1.6
Delay disc. indifference point, 24s delay1.32.13.7-1.9-1.81.71.4-1.2-1.31.11.0
Delay disc. indifference point, 4s delay0.20.20.60.7-0.40.8-0.30.2-0.2-0.20.1
Delay disc. indifference point, 8s delay0.10.20.30.50.10.6-0.50.50.3-0.5-0.4
Indifference point function ln k0.00.00.10.4-0.20.1-0.10.2-0.2-0.1-0.1
Indifference point function log k0.00.00.10.4-0.20.1-0.10.2-0.2-0.1-0.1
Patch foraging total patch changes 0 sec0.72.03.9-0.3-0.8-2.01.3-1.5-1.41.61.8
Patch foraging total patch changes 12 sec0.10.20.90.00.2-1.00.1-0.4-0.10.20.3
Patch foraging total patch changes 18 sec0.10.20.5-0.1-0.4-0.30.5-0.6-0.40.50.7
Patch foraging total patch changes 24 sec0.20.51.90.3-0.2-1.40.4-0.6-0.60.70.9
Patch foraging total patch changes 6 sec2.74.57.3-1.1-2.1-0.92.2-2.5-2.42.42.7
Patch foraging time to switch 0 sec0.20.82.7-1.6-0.11.60.2-0.00.4-0.2-0.7
Patch foraging water rate 0 sec0.00.10.70.60.1-0.8-0.10.2-0.1-0.00.1
Patch foraging water rate 12 sec0.20.72.10.7-0.4-1.40.5-0.5-0.90.81.1
Patch foraging water rate 18 sec0.30.81.40.0-0.7-1.20.8-0.7-1.11.01.0
Patch foraging water rate 24 sec0.20.21.21.10.3-0.4-0.40.40.2-0.30.0
Patch foraging water rate 6 sec0.30.41.00.2-1.0-0.20.4-0.4-0.90.50.8
Seeking ratio, delayed vs. immediate footshock0.00.00.20.10.2-0.50.10.10.20.10.1
Distance traveled before self-admin0.10.30.80.90.20.2-0.50.60.4-0.5-0.3
Distance traveled after self-admin1.83.25.82.41.5-0.0-2.02.11.6-2.0-1.7
Extensor digitorum longus weight4.919.728.05.35.0-1.2-4.84.74.5-4.5-4.1
Bone: elastic displacement1.11.42.2-0.9-1.50.21.3-1.2-1.41.31.4
Bone: elastic work0.10.10.50.70.0-0.1-0.20.5-0.0-0.20.1
Bone: endosteal estimation1.53.76.31.92.5-1.7-1.91.82.0-1.7-1.7
Bone: endosteal perimeter1.43.54.71.72.2-0.7-2.01.92.0-2.0-2.0
Epididymis fat weight0.21.16.91.20.7-2.6-0.40.4-0.0-0.00.2
Delta time in closed arm before/after self-admin2.01.92.80.71.60.8-1.41.41.7-1.5-1.6
Delta time in open arm before/after self-admin0.30.31.01.00.6-0.9-0.50.40.1-0.3-0.0
Diff in mean of infusions in LGA sessions1.22.12.8-1.0-1.5-1.01.5-1.6-1.71.61.7
Delay discount exponential model param0.10.20.80.20.6-0.9-0.20.20.4-0.1-0.2
Extinction: sum of active levers before priming0.10.20.8-0.9-0.20.70.4-0.4-0.20.30.1
Active lever presses in extinction session 60.20.20.4-0.3-0.2-0.30.5-0.6-0.40.60.5
Bone: final force2.74.49.93.12.1-1.5-2.22.21.7-1.9-1.5
Bone: final moment1.93.17.82.81.8-1.6-1.81.81.3-1.5-1.1
Food consumed during 24 hour testing period0.91.73.31.81.3-0.3-1.51.41.2-1.4-1.2
Glucose0.10.20.3-0.2-0.50.10.4-0.5-0.50.50.5
Heart weight0.10.10.40.2-0.6-0.3-0.10.1-0.6-0.00.0
Delay discount hyperbolic model param0.00.10.3-0.20.2-0.60.1-0.00.10.1-0.1
Intermittent access intake day 1-15 change0.10.61.00.20.11.0-0.70.80.9-0.9-0.9
Intermittent access intake escalation0.10.41.30.0-0.21.1-0.50.60.6-0.7-0.7
Intermittent access intake escalation 20.50.82.70.10.11.7-0.70.80.8-0.9-0.9
Intermitt. access day 1 inactive lever presses0.00.20.8-0.20.10.9-0.30.30.5-0.4-0.4
Intermitt. access day 15 inactive lever presses0.10.60.90.70.80.1-0.90.71.0-0.9-0.9
Intermitt. access escalation Index0.10.42.70.40.2-1.6-0.00.0-0.10.10.0
Intermittent access day 1 total infusions0.10.21.20.40.6-1.10.0-0.20.10.10.2
Intermittent access day 15 total infusions0.00.10.20.20.20.0-0.20.20.4-0.3-0.2
Intermittent access terminal intake (last 3 days)0.00.10.20.40.4-0.4-0.20.10.3-0.2-0.1
Intermittent access total infusions0.30.30.90.90.7-0.9-0.30.20.4-0.2-0.0
Intermittent access day 1 locomotion0.10.21.00.20.0-1.00.3-0.4-0.30.40.5
Intermittent access day 15 total locomotion0.20.71.4-0.6-0.7-0.40.9-1.2-0.70.91.0
Intermittent access total locomotion0.50.51.6-0.1-0.1-1.30.6-0.9-0.40.70.8
Intermittent access standard deviation0.63.34.62.01.60.6-2.02.12.0-2.0-1.8
Left kidney weight0.75.612.73.62.5-2.3-2.32.41.8-1.9-1.5
Right kidney weight0.74.611.93.52.4-2.5-2.02.01.4-1.5-1.0
Cocaine induced anxiety0.00.10.3-0.00.10.3-0.30.50.4-0.4-0.5
Post-drug Anxiety0.80.91.7-0.7-1.3-0.11.0-0.9-1.10.91.0
Baseline Anxiety0.60.91.60.0-1.1-0.70.9-1.1-1.11.01.2
Tail length0.10.62.31.50.4-1.4-0.30.3-0.0-0.10.3
Length with tail0.10.61.10.2-0.7-0.90.5-0.7-1.00.70.9
Length without tail0.31.53.3-1.2-1.81.01.0-1.0-1.61.00.9
Times rat made contact with spout4.14.75.92.12.00.9-2.42.42.3-2.4-2.3
Lifetime Intake0.40.41.21.10.8-1.1-0.40.30.5-0.3-0.1
Liver weight, left0.40.61.3-1.20.3-0.90.9-0.9-0.10.90.6
Liver weight, right0.20.30.8-0.80.9-0.20.3-0.30.60.2-0.1
Locomotor activity0.10.10.3-0.30.5-0.60.2-0.30.20.20.1
Locomotor testing distance0.00.10.30.00.4-0.60.0-0.10.20.10.1
Locomotor testing rearing0.10.50.8-0.9-0.1-0.90.8-0.8-0.40.90.7
Locomotion in novel chamber0.70.93.4-0.2-0.2-1.90.9-0.8-0.61.11.0
Locomotion in novel chamber post-restriction0.92.73.8-1.3-1.4-1.31.7-2.0-1.71.81.8
Fecal boli incidents, locomotor time 10.10.21.3-1.1-0.1-0.30.6-0.4-0.10.4-0.0
Change in fecal boli incidents, locomotor task1.31.32.50.2-1.2-0.81.0-1.2-1.51.21.6
Time >=10cm from walls, locomotor time 10.40.50.80.90.50.1-0.70.90.5-0.8-0.7
Bouts of movement, locomotor time 11.31.74.3-2.1-1.30.91.5-1.4-0.91.20.9
Total resting periods, locomotor time 11.61.94.8-2.2-1.21.21.5-1.4-0.91.30.9
Rest time, locomotor task time 10.30.52.8-0.7-0.41.70.1-0.10.1-0.2-0.4
Distance moved, locomotor task time 10.20.63.60.70.5-1.9-0.1-0.0-0.00.20.4
Vertical activity count, locomotor time 10.21.43.71.91.1-1.3-1.21.10.8-1.0-0.5
Time >=10cm from walls, locomotor time 20.61.83.01.71.30.2-1.51.61.2-1.4-1.2
Bouts of movement, locomotor time 20.31.12.90.01.7-1.1-0.70.51.4-0.8-1.2
Total resting periods, locomotor time 20.31.23.20.21.8-1.1-0.80.61.5-0.9-1.2
Rest time, locomotor task time 20.10.10.2-0.0-0.4-0.30.4-0.3-0.40.30.4
Distance moved, locomotor task time 21.31.72.31.31.20.7-1.51.51.3-1.5-1.3
Vertical activity count, locomotor time 20.30.61.31.20.40.4-1.00.90.6-1.0-0.6
Light reinforcement 10.41.72.4-1.3-1.1-0.81.5-1.6-1.21.51.3
Light reinforcement 20.41.01.3-0.7-0.8-1.01.1-1.0-1.01.21.1
Bone: marrow area1.43.45.91.82.4-1.6-1.81.72.0-1.6-1.6
Bone: maximum diameter1.52.95.02.22.0-1.7-1.71.61.5-1.5-1.3
Bone: maximum force2.24.39.53.12.1-1.2-2.22.21.7-1.9-1.5
Bone: maximum moment1.52.97.22.71.7-1.4-1.71.81.3-1.4-1.1
Mean time between licks in bursts0.00.10.3-0.60.1-0.20.1-0.10.2-0.0-0.3
Mean num. licks in bursts1.23.17.12.72.1-1.8-1.71.71.4-1.3-1.0
Cd content in liver6.47.19.8-2.2-2.1-2.13.0-3.1-2.53.13.0
Co content in liver0.70.82.30.2-1.50.60.5-0.4-1.30.61.0
Cu content in liver0.20.20.70.70.4-0.80.00.10.10.20.5
Fe content in liver0.40.50.9-0.3-0.80.40.7-0.5-0.70.70.9
K content in liver0.10.10.40.20.4-0.7-0.00.00.20.00.1
Mg content in liver0.20.20.8-0.10.7-0.9-0.10.20.5-0.1-0.2
Mn content in liver0.70.81.50.81.2-0.4-0.81.01.0-0.8-0.8
Na content in liver5.46.18.22.52.9-0.8-2.62.62.5-2.6-2.6
Rb content in liver7.99.213.9-2.4-3.0-0.93.4-3.1-3.23.53.7
Se content in liver0.50.61.20.70.50.2-0.91.10.5-0.9-0.9
Sr content in liver1.00.92.30.91.5-0.5-0.80.71.2-0.8-0.8
Zn content in liver1.01.25.20.81.2-2.3-0.70.60.7-0.5-0.6
Bone: minimum diameter1.73.34.52.12.1-1.2-1.91.91.8-1.7-1.7
Time in familiar zone, hab. session 10.70.81.2-0.5-1.00.20.9-1.0-0.90.91.1
Time in novel zone, hab. session 10.40.50.80.40.80.0-0.70.90.6-0.7-0.9
Total zone transitions, hab. session 10.50.73.61.90.1-1.1-0.80.5-0.3-0.5-0.1
Total locomotion distance, hab. session 11.11.65.82.40.7-2.3-0.90.5-0.1-0.40.1
Locomotion velocity, hab. session 11.01.46.52.00.5-2.6-0.60.2-0.2-0.10.3
Time in familiar zone, hab. session 20.20.20.70.70.1-0.8-0.30.2-0.0-0.3-0.1
Time in novel zone, hab. session 20.10.10.2-0.5-0.10.00.4-0.3-0.20.40.3
Total zone transitions, hab. session 20.40.52.01.40.3-1.2-0.40.1-0.2-0.20.1
Total locomotion distance, hab. session 20.60.83.51.90.5-1.4-0.80.3-0.0-0.4-0.0
Locomotion velocity, hab. session 20.81.14.32.10.8-1.5-1.00.50.3-0.7-0.3
Novel to familiar place preference ratio0.40.51.5-0.6-1.11.20.4-0.4-0.80.30.4
Novelty place preference0.50.62.3-0.5-1.21.50.2-0.3-0.80.10.2
Time in novel zone, NPP test0.60.71.8-0.6-1.41.10.5-0.5-1.10.40.5
Total zone transitions, NPP test0.30.52.11.40.4-0.9-0.70.40.1-0.5-0.3
Total locomotion distance, NPP test0.50.62.71.60.3-0.8-0.90.60.1-0.6-0.3
Locomotion velocity, NPP test0.40.62.41.50.3-0.6-0.80.60.2-0.6-0.3
Intraocular pressure0.10.10.20.30.3-0.1-0.40.40.1-0.3-0.3
Delta distance traveled before/after self-admin0.50.50.80.80.8-0.5-0.90.70.6-0.8-0.8
Delta ambulatory time before/after self-admin0.71.31.81.31.1-0.2-1.31.21.0-1.2-1.2
Parametrial fat weight1.12.513.11.20.3-3.60.8-0.8-0.81.21.6
Pavlov. Cond. lever latency1.82.24.9-0.2-2.20.81.2-1.4-2.01.31.8
Pavlov. Cond. magazine entry latency3.44.39.91.23.1-1.6-1.81.92.6-1.7-2.0
Pavlov. Cond. change in total contacts4.95.39.20.93.00.0-2.12.53.0-2.3-2.7
Pavlov. Cond. index score2.83.58.50.52.9-1.1-1.51.72.6-1.5-2.0
Pavlov. Cond. latency score2.32.97.20.52.7-1.1-1.31.52.4-1.4-1.8
Pavlov. Cond. lever contacts2.93.57.80.72.8-1.2-1.61.72.5-1.6-2.0
Pavlov. Cond. magazine entry number3.03.87.8-0.8-2.80.61.8-2.0-2.61.82.2
Pavlov. Cond. intertrial magazine entries3.03.65.9-1.2-2.40.11.9-1.9-2.42.02.1
Pavlov. Cond. lever-magazine prob. diff.3.34.19.90.73.1-1.3-1.61.82.8-1.6-2.1
Pavlov. Cond. response bias3.94.99.60.93.1-0.6-2.02.22.9-2.1-2.6
Pavlov. Cond. lever latency0.40.63.7-0.7-0.41.90.2-0.10.20.0-0.0
Pavlov. Cond. magazine entry latency0.20.20.7-0.80.10.7-0.00.10.4-0.2-0.5
Pavlov. Cond. change in total contacts0.92.33.1-0.8-1.2-1.71.5-1.6-1.61.71.8
Pavlov. Cond. index score0.10.20.8-0.3-0.0-0.90.3-0.3-0.30.30.2
Pavlov. Cond. latency score0.00.10.5-0.10.2-0.70.0-0.10.00.0-0.1
Pavlov. Cond. lever contacts0.40.53.70.60.5-1.9-0.20.1-0.1-0.0-0.0
Pavlov. Cond. magazine entry number0.70.92.61.60.9-0.7-1.01.00.6-0.8-0.6
Pavlov. Cond. intertrial magazine entries0.81.73.61.51.9-1.9-1.01.01.3-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.50.0-0.70.3-0.3-0.10.20.1
Pavlov. Cond. response bias0.20.31.7-0.2-0.0-1.30.3-0.4-0.40.40.3
Time in closed arm before self-admin0.00.10.50.3-0.1-0.7-0.10.0-0.1-0.1-0.0
Time in closed arm after self-admin0.20.30.5-0.4-0.70.50.5-0.5-0.60.40.5
Time in open arm before self-admin0.30.41.1-1.1-0.50.70.6-0.6-0.10.50.3
Time in open arm after self-admin2.93.24.11.92.0-0.2-2.02.01.9-1.9-1.8
Bone: periosteal estimation2.35.68.93.02.7-1.7-2.52.42.2-2.2-2.0
Bone: periosteal perimeter1.12.13.11.71.8-1.5-1.41.41.4-1.3-1.2
Bone: post-yield work1.01.77.71.11.9-2.8-0.30.20.9-0.00.0
Progressive ratio test 1 active lever presses0.20.31.10.50.8-1.1-0.20.20.6-0.2-0.3
Progressive ratio test 1 breakpoint0.20.31.00.40.8-1.0-0.20.20.5-0.2-0.3
Progressive ratio test 1 inactive lever presses0.00.10.40.10.4-0.6-0.2-0.00.4-0.3-0.4
Progressive ratio test 2 active lever presses0.10.10.3-0.30.1-0.60.3-0.5-0.00.30.2
Progressive ratio test 2 breakpoint0.10.20.4-0.4-0.0-0.60.5-0.6-0.20.40.3
Progressive ratio test 2 inactive lever presses0.10.20.80.30.7-0.9-0.2-0.00.5-0.2-0.2
Incentive Sensitization - Responses0.00.00.1-0.30.10.20.1-0.20.10.1-0.1
Incentive Sensitization - Breakpoint0.00.00.1-0.30.00.10.2-0.3-0.00.20.1
Sum of active levers in priming session hrs 5-61.41.33.4-1.8-0.5-0.51.4-1.3-0.71.30.9
Progressive ratio0.30.91.5-0.3-0.6-1.21.0-1.1-0.91.11.2
Food seeking constrained by brief footshock0.60.81.5-0.9-1.20.90.9-0.5-0.90.80.8
Seeking ratio, punishment vs. effort0.51.01.80.50.81.0-1.01.30.9-1.1-1.3
Retroperitoneal fat weight1.46.324.6-0.0-0.5-5.02.0-1.9-2.02.52.7
Reaction time number correct0.20.81.6-1.3-0.70.41.0-1.1-0.70.90.7
Reaction time mean minus median0.00.10.10.30.3-0.4-0.30.10.3-0.3-0.1
Reaction time mean minus median AUC0.10.71.0-0.7-0.6-0.70.9-1.0-0.80.91.0
Reaction time num false alarms0.30.42.0-0.0-0.11.4-0.50.40.5-0.6-0.6
Reaction time num false alarms AUC0.10.31.0-0.10.11.0-0.50.40.6-0.6-0.6
Reaction time trials correct on left0.20.81.6-1.3-0.70.41.0-1.1-0.70.90.7
Reaction time trials on left0.20.81.7-1.3-0.70.31.0-1.1-0.70.90.7
Reaction time mean0.10.21.00.20.4-1.0-0.00.00.10.00.1
Reaction time mean AUC0.00.10.6-0.10.3-0.80.1-0.00.00.10.1
Median of all reaction times0.10.21.40.20.5-1.2-0.00.10.10.00.1
Reaction time omissions0.20.30.9-0.9-0.0-0.70.6-0.5-0.40.50.2
Reaction time false alarm rate0.70.91.40.60.51.0-1.11.11.0-1.2-1.1
Reaction time premature initiation rate1.72.73.41.81.80.4-1.81.71.8-1.8-1.6
Reaction time premature initiations0.41.21.70.91.20.8-1.21.01.3-1.2-1.2
Std. dev. reaction times0.00.10.70.20.1-0.80.1-0.2-0.20.20.3
Reaction time trials completed0.20.81.7-1.3-0.70.31.0-1.1-0.70.90.7
Reaction time trials AUC0.20.61.2-1.1-0.60.20.9-1.0-0.60.80.6
Run reversals in cocaine runway, females5.46.09.53.12.4-0.1-2.82.92.3-2.6-2.2
Run reversals in cocaine runway, males0.20.20.9-0.5-0.60.90.2-0.4-0.30.10.1
Latency to leave start box in cocaine runway1.52.14.0-0.7-1.5-1.01.4-1.6-2.01.51.6
Latency to leave start box in cocaine runway, F0.60.71.7-0.7-0.8-0.40.9-0.8-1.30.90.7
Latency to leave start box in cocaine runway, M1.91.82.8-0.4-1.4-1.01.3-1.5-1.61.41.7
Std. dev. time between licks in bursts0.20.41.6-0.10.8-1.3-0.20.20.7-0.2-0.5
Total sessions with >9 infusions1.62.04.92.11.8-2.2-1.10.91.0-0.7-0.5
Short access day 1 total inactive lever presses0.10.20.50.70.4-0.7-0.50.20.4-0.5-0.4
Short access day 10 total inactive lever presses0.10.42.0-0.9-0.71.40.1-0.2-0.0-0.1-0.3
Short access day 1 total infusions0.40.71.81.31.0-0.9-0.80.70.6-0.7-0.5
Short access day 10 total infusions0.71.22.21.51.5-1.4-0.90.81.0-0.8-0.7
Short access total infusions0.91.33.11.81.4-1.6-0.90.80.8-0.6-0.4
Short access day 1 locomotion0.20.41.01.00.6-0.2-0.60.70.5-0.6-0.3
Short access day 10 total locomotion0.72.94.22.12.0-1.8-1.61.51.6-1.4-1.3
Short access total locomotion0.81.25.81.51.0-2.4-0.40.20.3-0.10.2
One hour access (0.3 mA shock)0.30.31.0-0.40.1-1.00.6-0.6-0.10.60.5
Compulsive drug intake0.40.50.8-0.7-0.4-0.50.8-0.9-0.90.90.7
One hour access (shock baseline)0.00.00.1-0.2-0.1-0.30.3-0.30.00.20.2
Social response proportion1.11.31.8-1.0-0.8-1.11.2-1.3-1.11.31.2
Social responses0.81.01.9-1.4-0.8-0.71.1-1.2-0.91.10.8
Social time1.11.72.2-1.5-1.40.11.4-1.4-1.41.31.3
Soleus weight0.82.58.62.91.4-1.0-1.71.50.8-1.3-0.7
Bone: stiffness2.03.68.22.91.7-0.5-2.22.11.5-2.0-1.6
Tibialis anterior weight3.411.627.65.33.4-2.3-3.73.42.6-3.2-2.5
Time to tail flick, vehicle, before self-admin0.10.10.20.50.30.3-0.40.30.2-0.3-0.2
Time to tail flick, vehicle, after self-admin1.02.04.8-2.2-1.40.71.5-1.5-1.31.30.9
Time to tail flick, test, before self-admin0.60.71.00.50.60.5-0.91.00.8-1.0-1.0
Time to tail flick, test, after self-admin2.62.74.00.31.51.7-1.51.72.0-1.8-2.0
Delta time to tail flick, vehicle, before/after SA0.70.81.3-1.1-0.7-0.11.0-1.0-0.91.00.8
Delta time to tail flick, test, before/after SA0.40.50.90.40.90.1-0.60.71.0-0.7-0.7
Tibia length0.10.20.50.1-0.3-0.60.4-0.4-0.40.50.7
Ambulatory time before self-admin0.00.10.40.6-0.40.4-0.10.2-0.1-0.10.1
Ambulatory time after self-admin1.93.05.92.41.30.3-2.02.01.5-1.9-1.6
Bone: tissue strength0.30.40.70.70.30.2-0.70.80.6-0.7-0.6
Total heroin consumption1.21.42.3-1.5-0.7-0.61.4-1.4-0.91.41.1
Bone: trabecular number0.20.41.61.30.4-0.5-0.80.60.2-0.6-0.4
Bone: trabecular spacing0.20.31.9-1.40.20.10.6-0.40.30.4-0.0
Bone: trabecular thickness1.01.33.41.1-0.6-1.80.6-0.8-1.21.01.5
Bone: trabecular tissue density0.00.10.40.2-0.60.0-0.10.0-0.4-0.10.0
Water consumed over 24 hours1.93.79.00.61.33.0-1.71.82.0-2.0-2.1
Number of responses in last shaping day0.30.40.50.60.7-0.4-0.60.60.6-0.6-0.6