Hub : Genes

LOC120098971

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression LOC120098971 0.7 0.15 3.7e-03 0.15 0.07 0.13 0.16 2.8e-03 2.9e-02 4.9e-03 1.6e-03
2 PL alternative TSS XR_010061016.1 0.05 0.03 3.6e-04 0.03 0.03 0.02 0.02 8.3e-04 3.5e-04 3.4e-03 3.9e-03
3 Brain alternative TSS XR_010061012.1 0.02 0.02 4.7e-03 0.01 0.01 0 0 4.2e-02 3.0e-02 3.2e-01 1.2e-01
4 Brain alternative TSS XR_010061013.1 0.02 0.02 3.3e-03 0.03 0.02 0.03 0.02 1.3e-03 2.5e-03 1.4e-03 2.8e-03
5 Brain mRNA stability LOC120098971 0.05 0.03 3.8e-07 0.06 0.06 0.05 0.05 4.4e-06 1.2e-06 1.1e-05 1.1e-05
6 Liver gene expression LOC120098971 0.26 0.1 0.0e+00 0.39 0.37 0.39 0.35 8.2e-46 2.1e-43 2.0e-45 2.4e-40
7 PL mRNA stability LOC120098971 0.02 0.02 8.6e-03 0 0.01 -0 0 8.6e-02 7.3e-02 5.5e-01 2.0e-01
8 Liver mRNA stability LOC120098971 0.03 0.02 6.9e-03 -0 -0 -0 -0 8.9e-01 5.9e-01 4.3e-01 9.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.40.70.30.8-0.7-0.8-0.7-0.9-0.5-0.5
Area under the delay curve0.40.61.2-0.1-1.10.61.00.60.91.0-0.7
BMI with tail1.86.112.33.5-1.92.42.52.82.52.60.8
BMI without tail0.95.06.72.2-2.12.32.52.62.62.40.6
Body weight4.419.130.1-0.3-5.54.65.24.75.35.00.1
Weight adjusted by age0.30.81.9-0.5-1.20.40.80.41.01.1-1.4
Bone surface0.10.21.6-1.3-0.30.10.1-0.10.10.10.1
Bone volume0.10.10.2-0.4-0.50.30.30.20.40.4-0.3
Breakpoint value in progressive ratio session0.20.31.30.50.70.4-0.10.2-0.2-0.21.1
Number of licking bursts0.20.71.7-1.30.6-0.6-0.7-0.7-0.5-1.10.9
Context. condit. distance diff. score1.01.25.2-2.30.4-0.7-0.7-1.0-1.0-1.00.1
Locomotion velocity, session 11.01.12.2-1.50.2-1.3-0.8-1.3-0.8-0.8-1.1
Locomotion distance, session 12.53.25.4-0.01.9-2.3-2.1-2.1-1.8-2.0-0.5
Locomotion velocity, session 20.50.61.7-1.30.5-0.5-0.6-0.7-0.7-0.90.7
Locomotion distance, session 20.71.01.7-0.30.9-1.3-1.2-1.3-1.1-1.0-0.5
Locomotion velocity, session 30.30.41.10.2-1.10.30.80.60.60.50.4
Locomotion distance, session 30.20.30.70.30.3-0.8-0.5-0.6-0.5-0.7-0.2
Stereotopy head waving bouts, day 31.82.23.6-1.6-1.91.41.61.31.81.20.7
Stereotopy head waving duration, day 30.30.31.9-1.4-0.60.20.30.10.50.3-0.1
Locomotion velocity, session 70.40.52.40.2-0.4-0.7-0.1-0.5-0.50.2-1.6
Locomotion distance, session 71.11.44.6-0.20.4-1.5-0.9-1.4-1.2-0.6-2.2
Stereotopy head waving bouts, day 70.91.12.2-0.0-1.50.81.21.11.40.90.7
Stereotopy head waving duration, day 71.01.32.10.2-1.41.01.31.21.41.01.0
Locomotion velocity, session 81.11.39.4-3.1-0.5-0.3-0.1-0.6-0.2-0.40.1
Locomotion distance, session 81.11.73.5-1.90.8-1.3-1.2-1.5-1.3-1.4-0.1
Degree of sensitization distance0.30.31.3-1.1-0.10.1-0.1-0.2-0.20.3-0.8
Degree of sensitization stereotypy0.10.10.30.5-0.2-0.10.20.20.2-0.10.6
Conditioned locomotion2.22.64.7-0.4-1.62.21.91.91.71.61.0
Cocaine response after cond. corrected0.40.61.80.6-0.40.90.70.90.60.61.3
Cocaine response after cond. not corrected0.40.61.8-0.3-0.60.80.70.80.60.51.3
Cocaine response before conditioning0.40.43.0-1.7-0.5-0.10.1-0.20.1-0.0-0.3
Saline control response0.81.24.52.1-0.11.10.71.10.81.10.2
Bone: connectivity density0.20.30.8-0.20.5-0.5-0.6-0.6-0.9-0.3-0.4
Bone: cortical apparent density0.30.53.01.70.50.30.00.4-0.00.10.6
Bone: cortical area0.00.10.20.0-0.5-0.10.20.00.20.3-0.3
Bone: cortical porosity0.40.42.3-0.4-0.5-0.6-0.0-0.5-0.00.0-1.5
Bone: cortical porosity0.70.84.4-0.8-0.6-0.8-0.1-0.7-0.00.1-2.1
Bone: cortical thickness0.81.36.52.60.9-1.1-0.8-0.6-0.7-0.5-0.2
Bone: cortical thickness0.81.07.12.70.50.20.00.40.10.30.5
Bone: cortical tissue density0.20.42.21.50.30.40.10.50.10.20.6
Condit. Reinf. active minus inactive responses0.80.93.4-0.20.7-0.9-0.9-1.0-0.8-0.4-1.8
Condit. Reinf. active-inactive response ratio0.10.10.40.60.50.2-0.30.00.10.0-0.4
Condit. Reinf. active responses0.40.43.00.30.2-0.4-0.3-0.4-0.30.2-1.7
Condit. Reinf. inactive responses0.20.31.10.80.3-0.4-0.3-0.4-0.50.1-1.0
Incentive salience index mean0.50.62.1-0.90.1-0.7-0.5-0.8-0.4-0.3-1.5
Condit. Reinf. lever presses0.20.42.0-1.4-0.5-0.4-0.0-0.4-0.0-0.1-0.6
Condit. Reinf. active minus inactive responses0.40.61.1-1.10.5-0.7-0.8-0.9-0.5-0.7-0.8
Condit. Reinf. active-inactive response ratio0.10.20.9-0.90.2-0.3-0.4-0.5-0.1-0.3-0.6
Condit. Reinf. active responses0.50.81.1-1.00.6-0.9-0.9-1.0-0.8-0.8-0.8
Condit. Reinf. inactive responses0.00.00.0-0.1-0.10.00.10.1-0.10.10.1
Condit. Reinf. lever presses3.24.66.3-0.62.4-2.2-2.5-2.5-2.4-2.2-1.7
Condit. Reinf. lever reinforcers received1.11.52.2-1.11.0-1.3-1.4-1.5-1.2-1.2-1.0
Conditioned reinforcement - actives0.10.51.40.1-1.20.10.60.30.80.8-1.0
Conditioned reinforcement - inactives0.00.10.60.2-0.1-0.4-0.1-0.3-0.1-0.1-0.8
Conditioned locomotion1.01.53.0-0.1-1.70.71.30.81.21.5-1.6
Patch foraging indifference point 0 sec0.30.72.61.6-0.40.70.60.90.80.80.2
Patch foraging indifference point AUC0.20.52.5-1.60.2-0.4-0.5-0.6-0.3-0.70.4
Delay disc. indifference point, 0s delay0.10.10.2-0.2-0.3-0.10.2-0.1-0.20.2-0.4
Delay disc. indifference point, 16s delay0.20.40.8-0.0-0.90.10.50.20.80.6-0.8
Delay disc. indifference point, 2s delay0.30.31.0-0.40.3-0.5-0.4-0.6-0.4-0.2-1.0
Delay disc. indifference point, 24s delay1.11.83.20.6-1.80.81.41.01.61.7-1.4
Delay disc. indifference point, 4s delay0.70.81.3-0.3-1.01.01.10.90.91.00.1
Delay disc. indifference point, 8s delay0.81.42.5-0.3-1.61.01.41.01.31.4-0.8
Indifference point function ln k0.10.20.3-0.50.1-0.5-0.3-0.5-0.4-0.4-0.0
Indifference point function log k0.10.20.3-0.50.1-0.5-0.3-0.5-0.4-0.4-0.0
Patch foraging total patch changes 0 sec0.30.83.51.9-0.40.60.60.80.80.80.1
Patch foraging total patch changes 12 sec0.10.20.60.60.4-0.1-0.2-0.0-0.1-0.40.8
Patch foraging total patch changes 18 sec0.51.23.92.0-0.41.00.81.21.10.80.7
Patch foraging total patch changes 24 sec0.20.84.12.01.1-0.4-0.7-0.3-0.4-0.4-0.3
Patch foraging total patch changes 6 sec0.30.53.61.90.20.40.20.50.20.30.2
Patch foraging time to switch 0 sec0.51.84.72.2-0.41.51.11.61.01.31.0
Patch foraging water rate 0 sec0.10.20.5-0.30.1-0.6-0.4-0.5-0.1-0.4-0.7
Patch foraging water rate 12 sec0.00.20.40.70.4-0.5-0.3-0.3-0.2-0.5-0.0
Patch foraging water rate 18 sec0.10.30.70.50.6-0.3-0.5-0.4-0.3-0.2-0.8
Patch foraging water rate 24 sec0.30.41.00.30.9-0.6-0.7-0.5-0.3-1.00.4
Patch foraging water rate 6 sec0.10.20.40.00.5-0.5-0.4-0.4-0.4-0.60.2
Seeking ratio, delayed vs. immediate footshock0.30.52.6-0.50.10.70.20.60.2-0.11.6
Distance traveled before self-admin0.51.12.0-0.5-0.81.31.01.21.10.61.4
Distance traveled after self-admin0.50.82.5-1.1-0.31.10.50.90.70.21.6
Extensor digitorum longus weight0.41.67.6-2.80.6-0.8-1.0-1.2-0.7-1.2-0.1
Bone: elastic displacement0.30.42.10.7-0.3-0.6-0.2-0.40.30.1-1.5
Bone: elastic work0.30.31.50.8-0.2-0.2-0.0-0.10.50.4-1.2
Bone: endosteal estimation2.45.88.1-2.8-2.82.62.62.22.62.30.3
Bone: endosteal perimeter1.23.05.3-2.3-1.92.01.81.61.71.40.6
Epididymis fat weight2.210.970.08.40.31.71.32.51.41.90.9
Delta time in closed arm before/after self-admin1.71.62.21.5-1.41.01.31.21.31.5-0.5
Delta time in open arm before/after self-admin0.40.40.7-0.50.8-0.6-0.7-0.7-0.8-0.70.2
Diff in mean of infusions in LGA sessions0.30.61.70.31.3-0.3-0.9-0.5-0.7-0.80.6
Delay discount exponential model param0.40.61.10.11.0-0.5-0.9-0.5-0.9-0.90.8
Extinction: sum of active levers before priming0.10.10.20.30.3-0.3-0.2-0.2-0.4-0.30.3
Active lever presses in extinction session 60.50.52.31.20.0-0.2-0.1-0.10.10.5-1.5
Bone: final force2.94.86.81.9-2.02.32.42.52.62.40.7
Bone: final moment2.23.65.21.6-1.82.02.12.22.32.20.3
Food consumed during 24 hour testing period0.40.72.1-0.0-0.21.40.71.10.70.80.9
Glucose1.11.810.2-3.2-0.5-0.8-0.3-1.0-0.5-0.4-1.2
Heart weight1.62.54.4-0.80.9-2.1-1.6-2.0-1.4-1.2-2.1
Delay discount hyperbolic model param0.30.30.60.30.8-0.3-0.6-0.3-0.6-0.70.7
Intermittent access intake day 1-15 change0.21.11.80.5-0.81.31.01.31.20.91.2
Intermittent access intake escalation0.21.32.01.0-0.91.31.11.41.31.11.0
Intermittent access intake escalation 20.20.30.6-0.8-0.70.50.50.50.60.60.1
Intermitt. access day 1 inactive lever presses0.22.03.5-1.61.4-1.0-1.2-1.0-1.4-1.91.6
Intermitt. access day 15 inactive lever presses0.20.81.8-1.3-1.00.91.00.80.90.50.6
Intermitt. access escalation Index0.31.02.6-0.21.3-0.6-0.8-0.6-0.9-1.31.6
Intermittent access day 1 total infusions0.61.76.3-0.10.1-1.7-0.9-1.5-0.9-0.5-2.5
Intermittent access day 15 total infusions0.10.20.70.8-0.5-0.20.1-0.00.20.4-0.8
Intermittent access terminal intake (last 3 days)0.20.31.10.7-0.7-0.20.20.00.30.5-1.1
Intermittent access total infusions0.40.52.50.2-0.3-0.8-0.3-0.6-0.20.0-1.6
Intermittent access day 1 locomotion0.10.20.6-0.2-0.60.00.30.10.30.3-0.8
Intermittent access day 15 total locomotion1.34.97.6-0.0-2.82.42.52.42.72.6-0.3
Intermittent access total locomotion1.01.22.2-0.4-1.51.01.21.01.21.3-0.9
Intermittent access standard deviation0.31.72.70.9-1.11.61.31.61.41.30.9
Left kidney weight1.411.217.8-0.1-4.23.54.03.64.03.70.7
Right kidney weight2.517.827.2-0.4-5.24.65.24.64.74.71.1
Cocaine induced anxiety0.30.73.7-1.90.20.1-0.2-0.1-0.2-0.51.2
Post-drug Anxiety0.30.31.2-1.10.50.2-0.3-0.1-0.2-0.40.9
Baseline Anxiety0.40.75.22.30.60.2-0.10.3-0.00.3-0.2
Tail length1.15.814.9-3.9-3.21.92.41.62.51.8-0.1
Length with tail2.711.721.8-4.6-4.72.93.62.53.63.1-0.8
Length without tail1.68.415.1-1.7-3.92.93.22.73.43.3-1.0
Times rat made contact with spout1.92.24.21.22.0-1.4-1.7-1.4-1.6-1.4-0.6
Lifetime Intake0.30.42.40.3-0.6-0.40.0-0.30.00.4-1.5
Liver weight, left1.42.43.4-1.8-1.71.81.61.51.51.40.7
Liver weight, right3.05.214.9-3.9-2.72.22.11.72.11.50.9
Locomotor activity0.30.52.5-0.8-0.20.50.30.50.5-0.21.6
Locomotor testing distance0.20.42.60.60.50.3-0.10.30.1-0.41.6
Locomotor testing rearing0.41.32.60.2-0.71.51.11.41.30.81.6
Locomotion in novel chamber0.50.71.00.30.8-1.0-1.0-0.9-0.8-0.8-0.6
Locomotion in novel chamber post-restriction0.82.33.31.6-1.21.61.51.71.81.70.2
Fecal boli incidents, locomotor time 10.00.10.40.1-0.00.20.10.0-0.00.4-0.6
Change in fecal boli incidents, locomotor task0.20.30.40.4-0.30.70.60.70.40.40.5
Time >=10cm from walls, locomotor time 11.62.03.80.6-0.52.01.21.81.41.11.9
Bouts of movement, locomotor time 10.40.51.5-1.00.7-0.0-0.5-0.2-0.5-0.71.2
Total resting periods, locomotor time 10.40.42.1-1.40.20.2-0.10.0-0.2-0.31.0
Rest time, locomotor task time 10.20.31.0-1.0-0.8-0.10.3-0.0-0.00.3-0.6
Distance moved, locomotor task time 10.10.40.80.9-0.10.70.40.70.90.40.5
Vertical activity count, locomotor time 10.21.12.11.1-0.21.40.91.21.10.91.0
Time >=10cm from walls, locomotor time 21.43.96.31.7-1.92.22.32.21.82.5-0.2
Bouts of movement, locomotor time 20.20.83.3-1.8-0.10.80.20.50.4-0.01.3
Total resting periods, locomotor time 20.20.84.5-2.10.30.3-0.2-0.0-0.1-0.51.2
Rest time, locomotor task time 20.20.42.1-1.40.10.10.0-0.0-0.2-0.51.0
Distance moved, locomotor task time 22.33.15.11.8-1.81.61.81.71.82.3-1.0
Vertical activity count, locomotor time 20.71.73.21.0-1.31.31.31.21.31.8-1.0
Light reinforcement 10.73.04.71.1-1.12.11.82.21.61.42.1
Light reinforcement 21.12.44.70.2-1.32.21.82.01.51.51.2
Bone: marrow area2.45.98.3-2.7-2.92.72.62.22.72.40.3
Bone: maximum diameter0.51.16.5-2.5-1.20.30.60.10.40.3-0.3
Bone: maximum force0.81.52.60.7-1.41.11.41.31.61.5-0.2
Bone: maximum moment0.51.01.70.4-1.30.81.10.91.31.2-0.7
Mean time between licks in bursts0.52.915.3-3.90.4-1.0-1.0-1.4-0.9-1.60.8
Mean num. licks in bursts0.30.73.01.70.8-0.4-0.5-0.3-0.7-0.0-1.1
Cd content in liver0.40.41.61.20.10.20.30.10.10.7-1.2
Co content in liver2.22.55.82.4-1.11.61.61.71.31.9-0.3
Cu content in liver2.53.05.22.02.3-1.7-1.8-1.5-2.0-1.60.0
Fe content in liver1.51.93.10.3-1.81.41.71.51.51.60.3
K content in liver0.90.92.1-1.50.4-1.0-0.9-1.1-0.7-1.0-0.7
Mg content in liver1.61.86.3-2.50.8-1.0-1.1-1.3-1.1-1.40.0
Mn content in liver1.82.014.8-3.8-0.70.10.0-0.30.1-0.50.4
Na content in liver0.10.10.40.30.2-0.1-0.1-0.00.2-0.40.7
Rb content in liver0.00.00.20.10.20.0-0.2-0.10.00.1-0.5
Se content in liver2.63.112.6-3.50.6-1.5-1.3-1.8-1.2-1.7-0.3
Sr content in liver0.20.21.30.4-0.0-0.1-0.1-0.1-0.10.3-1.2
Zn content in liver1.21.42.9-1.70.7-1.1-1.0-1.3-1.3-1.0-0.9
Bone: minimum diameter0.71.42.8-1.7-1.51.21.20.91.21.1-0.0
Time in familiar zone, hab. session 10.20.21.11.10.1-0.4-0.1-0.2-0.10.1-0.7
Time in novel zone, hab. session 10.20.20.4-0.5-0.60.50.60.50.40.40.3
Total zone transitions, hab. session 11.92.74.50.31.8-2.1-1.9-1.8-1.8-2.00.1
Total locomotion distance, hab. session 11.42.03.5-0.31.4-1.9-1.6-1.6-1.4-1.80.1
Locomotion velocity, hab. session 11.31.93.6-0.51.2-1.9-1.5-1.7-1.3-1.7-0.1
Time in familiar zone, hab. session 21.51.73.7-0.31.8-0.6-1.3-0.8-1.3-1.61.9
Time in novel zone, hab. session 21.92.15.00.5-1.70.81.30.91.41.8-2.2
Total zone transitions, hab. session 20.50.61.60.20.9-0.7-0.7-0.5-0.4-1.11.3
Total locomotion distance, hab. session 22.02.75.1-0.22.0-1.6-1.8-1.5-1.4-2.21.5
Locomotion velocity, hab. session 22.43.26.1-0.42.1-1.9-2.0-1.7-1.6-2.51.4
Novel to familiar place preference ratio0.30.30.50.7-0.70.00.50.30.60.7-0.7
Novelty place preference0.20.30.50.5-0.70.00.50.20.50.6-0.7
Time in novel zone, NPP test0.30.30.60.5-0.80.20.60.30.60.7-0.7
Total zone transitions, NPP test1.31.93.1-0.31.4-1.7-1.6-1.6-1.4-1.7-0.1
Total locomotion distance, NPP test1.11.52.30.41.4-1.5-1.4-1.4-1.2-1.3-0.7
Locomotion velocity, NPP test1.62.23.20.61.8-1.8-1.8-1.6-1.5-1.7-0.3
Intraocular pressure0.71.11.9-0.1-1.41.01.31.11.31.2-0.0
Delta distance traveled before/after self-admin0.20.30.5-0.30.6-0.4-0.7-0.6-0.5-0.4-0.5
Delta ambulatory time before/after self-admin0.10.20.3-0.50.6-0.2-0.5-0.4-0.4-0.3-0.0
Parametrial fat weight3.48.012.51.3-2.43.53.13.53.12.82.2
Pavlov. Cond. lever latency1.31.64.32.10.41.60.71.50.60.81.4
Pavlov. Cond. magazine entry latency1.31.76.1-2.50.1-1.3-0.9-1.4-0.8-1.0-1.0
Pavlov. Cond. change in total contacts0.70.82.1-1.2-1.50.10.80.20.80.6-1.0
Pavlov. Cond. index score1.21.55.6-2.4-0.5-1.4-0.5-1.3-0.4-0.7-1.4
Pavlov. Cond. latency score1.11.45.9-2.4-0.6-1.3-0.4-1.2-0.3-0.6-1.2
Pavlov. Cond. lever contacts0.91.03.1-1.7-0.6-1.2-0.3-1.0-0.2-0.4-1.4
Pavlov. Cond. magazine entry number1.41.83.92.0-0.51.61.21.61.01.30.7
Pavlov. Cond. intertrial magazine entries0.70.93.61.90.10.10.10.20.00.8-1.6
Pavlov. Cond. lever-magazine prob. diff.1.11.44.5-2.1-0.6-1.4-0.5-1.2-0.4-0.6-1.4
Pavlov. Cond. response bias1.62.05.9-2.40.1-1.7-1.0-1.7-0.9-1.2-1.1
Pavlov. Cond. lever latency1.72.43.20.0-1.51.71.71.81.71.41.8
Pavlov. Cond. magazine entry latency0.30.40.9-0.8-0.70.50.40.30.50.7-0.9
Pavlov. Cond. change in total contacts0.51.11.5-0.11.1-1.1-1.2-1.2-1.1-0.9-1.2
Pavlov. Cond. index score0.40.72.6-0.60.4-0.7-0.7-0.8-0.6-0.4-1.6
Pavlov. Cond. latency score0.30.51.8-0.60.3-0.5-0.6-0.7-0.5-0.3-1.3
Pavlov. Cond. lever contacts1.32.03.00.21.4-1.6-1.5-1.6-1.5-1.2-1.7
Pavlov. Cond. magazine entry number0.10.10.7-0.00.2-0.3-0.2-0.2-0.1-0.40.9
Pavlov. Cond. intertrial magazine entries0.81.85.4-2.10.9-0.4-0.8-0.7-0.8-1.32.3
Pavlov. Cond. lever-magazine prob. diff.0.40.52.4-0.50.3-0.6-0.6-0.7-0.5-0.3-1.6
Pavlov. Cond. response bias0.91.34.0-0.40.6-1.2-1.0-1.3-1.0-0.6-2.0
Time in closed arm before self-admin0.20.40.7-0.30.8-0.6-0.8-0.7-0.5-0.6-0.3
Time in closed arm after self-admin0.50.51.91.40.0-0.6-0.3-0.4-0.10.1-1.3
Time in open arm before self-admin0.10.10.3-0.2-0.0-0.6-0.2-0.4-0.4-0.3-0.5
Time in open arm after self-admin0.60.61.9-1.40.6-0.6-0.6-0.7-0.9-0.80.2
Bone: periosteal estimation1.12.54.1-1.7-2.01.61.81.41.81.50.2
Bone: periosteal perimeter0.30.71.2-1.1-0.90.90.90.80.80.60.4
Bone: post-yield work0.40.72.5-1.6-1.10.30.60.20.70.7-0.6
Progressive ratio test 1 active lever presses0.20.31.90.8-0.1-0.3-0.2-0.3-0.10.2-1.4
Progressive ratio test 1 breakpoint0.20.42.00.70.0-0.5-0.3-0.4-0.20.1-1.4
Progressive ratio test 1 inactive lever presses0.30.82.51.6-0.70.80.81.00.80.80.2
Progressive ratio test 2 active lever presses0.10.20.70.8-0.1-0.2-0.1-0.1-0.00.1-0.7
Progressive ratio test 2 breakpoint0.10.20.70.9-0.1-0.3-0.2-0.2-0.10.1-0.8
Progressive ratio test 2 inactive lever presses0.10.21.1-0.5-0.3-0.4-0.2-0.4-0.1-0.0-1.1
Incentive Sensitization - Responses0.30.71.2-0.10.9-1.0-1.0-0.9-0.9-1.10.2
Incentive Sensitization - Breakpoint0.20.40.70.00.7-0.7-0.7-0.6-0.7-0.90.4
Sum of active levers in priming session hrs 5-60.10.10.2-0.30.0-0.4-0.2-0.4-0.1-0.2-0.5
Progressive ratio1.44.06.31.3-1.62.52.12.52.22.01.4
Food seeking constrained by brief footshock0.40.51.41.20.4-0.4-0.5-0.3-0.40.1-1.2
Seeking ratio, punishment vs. effort1.32.84.7-0.51.3-2.2-1.8-2.1-1.9-1.5-1.5
Retroperitoneal fat weight0.73.35.00.6-1.92.12.12.12.21.90.6
Reaction time number correct0.41.44.72.2-0.41.21.01.30.71.00.8
Reaction time mean minus median0.21.610.3-3.2-1.20.50.60.20.50.3-0.3
Reaction time mean minus median AUC0.21.57.9-2.8-1.20.30.5-0.00.50.5-1.3
Reaction time num false alarms0.40.73.7-1.90.1-0.2-0.4-0.4-0.0-0.81.0
Reaction time num false alarms AUC0.61.34.3-2.10.7-0.8-1.0-1.0-0.6-1.40.9
Reaction time trials correct on left0.41.44.72.2-0.41.21.01.30.71.00.8
Reaction time trials on left0.41.34.42.1-0.41.21.01.30.71.00.8
Reaction time mean0.40.94.5-2.1-1.00.40.60.10.40.6-0.8
Reaction time mean AUC0.51.13.7-1.9-1.30.70.90.40.70.9-0.9
Median of all reaction times0.30.51.5-1.2-0.80.40.60.20.40.6-0.8
Reaction time omissions0.50.83.9-2.0-0.50.70.40.40.5-0.01.1
Reaction time false alarm rate1.92.79.2-3.00.8-1.5-1.5-1.7-1.0-1.80.2
Reaction time premature initiation rate0.10.10.30.20.5-0.3-0.4-0.3-0.5-0.40.2
Reaction time premature initiations0.10.42.21.50.10.50.30.60.10.40.5
Std. dev. reaction times0.51.611.5-3.4-0.90.10.2-0.20.20.1-0.7
Reaction time trials completed0.41.34.42.1-0.41.21.01.30.71.00.8
Reaction time trials AUC0.41.44.52.1-0.41.21.01.30.71.00.8
Run reversals in cocaine runway, females0.60.63.20.8-0.6-0.20.4-0.00.20.7-1.8
Run reversals in cocaine runway, males1.11.25.4-2.3-1.60.40.90.30.50.6-0.4
Latency to leave start box in cocaine runway0.60.81.10.31.0-1.1-1.1-1.0-0.9-1.0-0.2
Latency to leave start box in cocaine runway, F0.50.60.90.20.9-1.0-1.0-0.9-0.8-0.9-0.3
Latency to leave start box in cocaine runway, M0.00.00.10.30.1-0.2-0.1-0.1-0.1-0.10.2
Std. dev. time between licks in bursts0.81.510.4-3.2-0.9-0.10.2-0.30.2-0.50.8
Total sessions with >9 infusions0.20.21.1-0.0-0.1-0.5-0.3-0.5-0.3-0.1-1.0
Short access day 1 total inactive lever presses0.30.61.4-1.1-1.1-0.00.50.00.60.6-1.2
Short access day 10 total inactive lever presses0.21.57.8-0.91.00.2-0.40.1-0.5-1.22.8
Short access day 1 total infusions0.30.72.1-0.70.1-1.0-0.7-0.9-0.6-0.4-1.5
Short access day 10 total infusions0.00.10.20.00.1-0.3-0.3-0.3-0.3-0.2-0.4
Short access total infusions0.20.32.00.2-0.3-0.5-0.1-0.4-0.10.2-1.4
Short access day 1 locomotion0.20.30.6-0.60.5-0.4-0.5-0.4-0.5-0.80.5
Short access day 10 total locomotion0.20.62.1-1.50.7-0.0-0.4-0.3-0.4-0.91.1
Short access total locomotion0.10.10.6-0.80.30.1-0.2-0.1-0.2-0.40.4
One hour access (0.3 mA shock)1.92.33.5-0.61.4-1.9-1.8-1.8-1.7-1.8-0.1
Compulsive drug intake1.82.73.8-1.71.8-1.4-1.7-1.6-1.7-1.91.2
One hour access (shock baseline)0.10.32.10.3-0.5-0.40.0-0.20.10.3-1.4
Social response proportion0.10.10.5-0.7-0.0-0.2-0.1-0.3-0.5-0.20.0
Social responses0.20.30.9-0.50.5-0.1-0.4-0.2-0.4-0.61.0
Social time1.32.18.0-2.80.4-0.0-0.4-0.3-0.3-1.22.6
Soleus weight1.44.126.6-5.2-1.90.60.80.11.20.3-0.7
Bone: stiffness0.61.01.40.8-1.01.11.21.21.01.10.6
Tibialis anterior weight0.41.53.0-0.11.7-1.1-1.5-1.2-1.4-1.50.3
Time to tail flick, vehicle, before self-admin2.63.38.1-1.1-1.32.11.72.01.70.92.8
Time to tail flick, vehicle, after self-admin0.30.51.0-0.11.0-0.7-0.9-0.8-0.8-0.80.0
Time to tail flick, test, before self-admin0.40.51.30.50.9-0.3-0.7-0.2-0.4-0.91.2
Time to tail flick, test, after self-admin0.10.10.8-0.9-0.2-0.10.0-0.10.2-0.10.3
Delta time to tail flick, vehicle, before/after SA3.23.56.41.51.6-2.1-1.8-2.0-1.9-1.0-2.5
Delta time to tail flick, test, before/after SA0.50.61.0-0.1-0.90.81.00.80.71.0-0.0
Tibia length2.46.69.6-1.9-3.12.83.02.62.92.51.3
Ambulatory time before self-admin0.10.30.9-0.3-0.30.60.40.60.50.11.0
Ambulatory time after self-admin0.20.31.1-1.00.10.50.00.30.2-0.11.1
Bone: tissue strength0.20.30.91.0-0.00.10.10.20.50.4-0.8
Total heroin consumption0.60.82.3-0.81.0-0.2-0.8-0.4-0.6-1.01.5
Bone: trabecular number0.50.92.10.51.0-1.0-1.0-1.0-1.4-0.7-0.4
Bone: trabecular spacing1.11.62.5-0.1-1.41.61.51.51.61.30.0
Bone: trabecular thickness0.40.51.00.2-1.00.50.70.60.81.0-0.4
Bone: trabecular tissue density0.20.31.0-1.0-0.8-0.10.3-0.00.50.2-0.7
Water consumed over 24 hours0.50.92.1-0.01.4-0.7-1.2-0.9-1.0-1.10.3
Number of responses in last shaping day1.11.53.8-0.80.1-1.6-0.8-1.5-1.0-0.7-2.0