Hub : Genes

LOC120098949

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	LOC120098949	0.2	0.15	5.5e-03	0.01	0.02	0.01	0	9.7e-02	4.7e-02	1.5e-01	2.4e-01
2	NAcc	gene expression	LOC120098949	0.03	0.03	4.9e-05	0.02	0.01	0.01	0.01	5.1e-04	1.9e-03	7.2e-03	3.6e-03
3	Adipose	mRNA stability	LOC120098949	0.04	0.04	2.0e-04	0.01	0.02	0.02	0.02	8.9e-03	2.3e-03	6.5e-03	5.5e-03
4	Adipose	gene expression	LOC120098949	0.12	0.08	2.1e-14	0.11	0.12	0.12	0.11	7.8e-12	4.3e-13	9.8e-13	2.5e-12
5	pVTA	gene expression	LOC120098949	0.05	0.04	4.4e-04	0.02	0.04	0.02	0.03	5.9e-03	4.5e-04	4.3e-03	2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Bone: apparent density	0.5	0.8	1.1	0.2	1.0	-0.9	1.0	1.1
Area under the delay curve	1.2	1.4	2.0	-1.4	-1.3	1.2	-1.1	-1.0
BMI with tail	2.2	7.6	9.2	-1.8	-3.0	2.8	-3.0	-3.0
BMI without tail	2.2	6.7	7.7	-2.1	-2.8	2.6	-2.7	-2.7
Body weight	6.0	26.4	27.8	-4.7	-5.2	5.2	-5.3	-5.3
Weight adjusted by age	0.7	1.1	1.9	0.6	-0.9	0.9	-1.3	-1.4
Bone surface	0.0	0.0	0.0	-0.1	0.0	0.0	-0.0	-0.0
Bone volume	0.0	0.1	0.3	-0.6	-0.1	0.2	-0.1	-0.1
Breakpoint value in progressive ratio session	0.0	0.0	0.0	0.2	0.2	-0.2	0.2	0.2
Number of licking bursts	0.4	0.6	0.7	0.8	0.8	-0.8	0.8	0.7
Context. condit. distance diff. score	0.3	0.3	0.5	0.7	0.4	-0.6	0.5	0.5
Locomotion velocity, session 1	0.6	0.7	0.9	0.5	0.9	-0.8	0.9	0.9
Locomotion distance, session 1	3.3	4.2	4.5	1.9	2.0	-2.1	2.1	2.1
Locomotion velocity, session 2	0.3	0.3	0.3	0.5	0.6	-0.6	0.6	0.6
Locomotion distance, session 2	0.9	1.2	1.4	1.2	1.0	-1.1	1.1	1.1
Locomotion velocity, session 3	0.5	0.6	1.7	-1.3	-0.6	0.7	-0.5	-0.5
Locomotion distance, session 3	0.2	0.2	0.3	-0.1	0.3	-0.4	0.6	0.6
Stereotopy head waving bouts, day 3	2.0	2.4	2.5	-1.5	-1.6	1.6	-1.6	-1.6
Stereotopy head waving duration, day 3	0.2	0.2	0.3	0.1	-0.5	0.4	-0.5	-0.5
Locomotion velocity, session 7	0.1	0.1	0.3	-0.5	0.2	-0.1	0.3	0.3
Locomotion distance, session 7	0.7	0.9	1.2	0.4	0.9	-0.9	1.1	1.1
Stereotopy head waving bouts, day 7	1.3	1.4	2.6	-1.6	-1.1	1.2	-1.0	-1.0
Stereotopy head waving duration, day 7	1.3	1.5	2.6	-1.6	-1.1	1.2	-1.1	-1.1
Locomotion velocity, session 8	0.0	0.0	0.0	0.0	-0.1	-0.1	0.1	0.1
Locomotion distance, session 8	0.9	1.3	1.7	1.3	1.0	-1.1	1.1	1.1
Degree of sensitization distance	0.0	0.0	0.2	0.4	0.1	-0.1	-0.1	-0.1
Degree of sensitization stereotypy	0.1	0.1	0.4	-0.6	0.1	0.0	0.1	0.2
Conditioned locomotion	2.5	2.9	3.1	-1.8	-1.6	1.7	-1.7	-1.7
Cocaine response after cond. corrected	0.8	1.0	1.5	0.1	-1.1	0.9	-1.2	-1.2
Cocaine response after cond. not corrected	0.8	0.9	1.3	-0.1	-1.1	0.9	-1.1	-1.1
Cocaine response before conditioning	0.1	0.1	0.5	-0.7	0.0	0.1	0.1	0.2
Saline control response	0.4	0.6	0.7	-0.9	-0.7	0.7	-0.7	-0.7
Bone: connectivity density	0.3	0.5	0.7	0.2	0.9	-0.7	0.8	0.9
Bone: cortical apparent density	0.1	0.1	0.2	-0.4	0.2	-0.1	0.2	0.3
Bone: cortical area	0.2	0.3	0.4	-0.0	-0.7	0.5	-0.6	-0.6
Bone: cortical porosity	0.0	0.0	0.1	0.3	0.0	-0.0	-0.0	-0.0
Bone: cortical porosity	0.0	0.0	0.1	0.3	0.0	-0.0	-0.1	-0.1
Bone: cortical thickness	0.2	0.4	0.6	0.8	0.6	-0.6	0.6	0.6
Bone: cortical thickness	0.0	0.0	0.1	-0.3	-0.1	0.1	-0.0	-0.0
Bone: cortical tissue density	0.0	0.1	0.2	-0.5	0.1	-0.0	0.1	0.2
Condit. Reinf. active minus inactive responses	0.8	0.9	1.1	0.6	1.0	-1.0	1.0	1.1
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	0.1	0.1	-0.2	0.2	0.2
Condit. Reinf. active responses	0.2	0.3	0.4	-0.1	0.6	-0.5	0.6	0.6
Condit. Reinf. inactive responses	0.3	0.4	0.6	-0.2	0.8	-0.5	0.7	0.7
Incentive salience index mean	0.3	0.4	0.5	0.3	0.7	-0.6	0.7	0.7
Condit. Reinf. lever presses	0.0	0.0	0.0	0.1	0.1	-0.1	0.1	0.1
Condit. Reinf. active minus inactive responses	0.6	0.8	1.0	0.8	1.0	-0.9	0.9	0.9
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.9	0.9	0.8	-0.6	0.5	0.4
Condit. Reinf. active responses	0.5	0.7	1.0	0.5	0.8	-0.9	1.0	1.0
Condit. Reinf. inactive responses	0.2	0.2	0.9	-1.0	-0.5	0.3	-0.1	-0.0
Condit. Reinf. lever presses	3.5	4.8	5.8	1.8	2.0	-2.3	2.4	2.4
Condit. Reinf. lever reinforcers received	1.1	1.6	2.0	0.9	1.2	-1.3	1.4	1.4
Conditioned reinforcement - actives	0.4	0.7	0.9	-1.0	-0.9	0.8	-0.7	-0.7
Conditioned reinforcement - inactives	0.0	0.0	0.0	0.1	0.2	-0.2	0.2	0.2
Conditioned locomotion	1.4	1.9	2.2	-1.5	-1.4	1.4	-1.3	-1.3
Patch foraging indifference point 0 sec	0.3	0.6	0.7	-0.8	-0.8	0.7	-0.7	-0.7
Patch foraging indifference point AUC	0.2	0.2	0.3	0.4	0.4	-0.5	0.5	0.5
Delay disc. indifference point, 0s delay	0.2	0.2	0.3	0.2	-0.6	0.4	-0.6	-0.6
Delay disc. indifference point, 16s delay	0.7	0.8	2.7	-1.6	-0.7	0.7	-0.4	-0.3
Delay disc. indifference point, 2s delay	0.1	0.1	0.4	0.6	0.2	-0.3	0.2	0.2
Delay disc. indifference point, 24s delay	2.5	2.8	3.7	-1.9	-1.7	1.6	-1.5	-1.5
Delay disc. indifference point, 4s delay	1.5	1.6	1.9	-1.2	-1.4	1.2	-1.3	-1.2
Delay disc. indifference point, 8s delay	2.1	2.4	3.3	-1.8	-1.6	1.5	-1.4	-1.4
Indifference point function ln k	0.1	0.1	0.2	0.4	0.4	-0.3	0.3	0.3
Indifference point function log k	0.1	0.1	0.2	0.4	0.4	-0.3	0.3	0.3
Patch foraging total patch changes 0 sec	0.3	0.5	0.6	-0.6	-0.8	0.7	-0.7	-0.7
Patch foraging total patch changes 12 sec	0.0	0.0	0.0	0.2	-0.1	-0.1	0.0	0.0
Patch foraging total patch changes 18 sec	0.7	1.0	1.7	-1.3	-1.1	0.9	-0.8	-0.8
Patch foraging total patch changes 24 sec	0.2	0.4	0.6	0.8	0.4	-0.6	0.6	0.6
Patch foraging total patch changes 6 sec	0.1	0.1	0.3	-0.3	-0.6	0.3	-0.3	-0.3
Patch foraging time to switch 0 sec	0.9	1.7	2.3	-1.0	-1.5	1.3	-1.4	-1.4
Patch foraging water rate 0 sec	0.1	0.3	0.5	0.7	0.6	-0.5	0.4	0.3
Patch foraging water rate 12 sec	0.1	0.1	0.2	0.2	0.4	-0.4	0.4	0.4
Patch foraging water rate 18 sec	0.3	0.4	0.6	-0.1	0.7	-0.6	0.7	0.8
Patch foraging water rate 24 sec	0.3	0.4	0.5	0.4	0.6	-0.6	0.7	0.7
Patch foraging water rate 6 sec	0.1	0.2	0.3	0.5	0.4	-0.4	0.3	0.4
Seeking ratio, delayed vs. immediate footshock	0.4	0.5	2.2	-1.5	0.1	0.1	0.2	0.3
Distance traveled before self-admin	0.7	1.0	1.0	-1.0	-0.9	1.0	-1.0	-1.0
Distance traveled after self-admin	0.1	0.1	0.2	-0.5	-0.1	0.4	-0.3	-0.3
Extensor digitorum longus weight	0.2	1.0	1.0	1.0	1.0	-1.0	1.0	1.0
Bone: elastic displacement	0.0	0.0	0.0	0.0	0.1	-0.1	0.2	0.2
Bone: elastic work	0.0	0.0	0.1	-0.0	-0.3	0.2	-0.2	-0.2
Bone: endosteal estimation	3.3	7.2	8.3	-2.4	-2.9	2.7	-2.7	-2.7
Bone: endosteal perimeter	1.8	3.8	4.5	-1.3	-2.1	2.0	-2.1	-2.1
Epididymis fat weight	0.7	2.3	2.8	-1.1	-1.7	1.5	-1.6	-1.6
Delta time in closed arm before/after self-admin	2.3	2.2	3.2	-0.4	-1.6	1.5	-1.7	-1.8
Delta time in open arm before/after self-admin	0.6	0.6	1.0	0.0	0.8	-0.8	0.9	1.0
Diff in mean of infusions in LGA sessions	0.7	0.8	1.8	1.3	0.7	-0.9	0.7	0.7
Delay discount exponential model param	1.1	1.2	1.8	1.4	1.1	-1.1	1.0	0.9
Extinction: sum of active levers before priming	0.5	0.5	2.4	1.5	0.3	-0.3	-0.1	-0.2
Active lever presses in extinction session 6	0.1	0.1	0.1	-0.4	-0.3	0.1	0.0	0.0
Bone: final force	3.9	6.3	7.2	-2.2	-2.7	2.5	-2.6	-2.5
Bone: final moment	3.4	5.5	6.6	-2.1	-2.6	2.3	-2.4	-2.3
Food consumed during 24 hour testing period	0.5	0.6	0.9	-0.3	-0.9	0.8	-0.9	-0.9
Glucose	0.1	0.2	1.1	1.1	-0.0	-0.1	-0.1	-0.2
Heart weight	1.9	3.0	7.0	2.6	1.6	-1.6	1.3	1.2
Delay discount hyperbolic model param	0.6	0.7	1.0	1.0	0.9	-0.8	0.8	0.7
Intermittent access intake day 1-15 change	0.5	1.1	2.5	-1.6	-0.9	0.9	-0.7	-0.7
Intermittent access intake escalation	0.7	1.5	4.3	-2.1	-1.0	1.0	-0.7	-0.7
Intermittent access intake escalation 2	0.3	0.3	1.4	-1.2	-0.1	0.3	-0.1	-0.0
Intermitt. access day 1 inactive lever presses	0.6	2.1	5.3	2.3	1.3	-1.3	1.0	0.9
Intermitt. access day 15 inactive lever presses	0.3	0.7	1.8	-1.3	-0.6	0.7	-0.6	-0.5
Intermitt. access escalation Index	0.5	0.7	0.7	0.7	0.8	-0.8	0.8	0.9
Intermittent access day 1 total infusions	0.4	0.6	0.8	0.5	0.8	-0.8	0.9	0.9
Intermittent access day 15 total infusions	0.2	0.3	1.2	-1.1	-0.2	0.2	0.1	0.2
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.4	-0.7	-0.2	0.3	-0.1	-0.1
Intermittent access total infusions	0.1	0.1	0.2	-0.4	0.2	-0.2	0.4	0.4
Intermittent access day 1 locomotion	0.2	0.2	0.5	-0.7	-0.4	0.4	-0.3	-0.3
Intermittent access day 15 total locomotion	3.5	6.3	11.1	-3.3	-2.2	2.5	-2.2	-2.1
Intermittent access total locomotion	1.5	1.8	4.7	-2.2	-1.1	1.2	-0.9	-0.9
Intermittent access standard deviation	0.9	1.9	2.2	-1.2	-1.5	1.4	-1.4	-1.4
Left kidney weight	3.4	15.7	16.2	-4.0	-3.9	4.0	-4.0	-3.9
Right kidney weight	6.2	28.1	31.7	-5.6	-5.3	5.3	-5.1	-5.1
Cocaine induced anxiety	0.1	0.1	0.2	0.0	0.5	-0.4	0.4	0.4
Post-drug Anxiety	0.3	0.3	0.4	0.1	0.6	-0.5	0.6	0.6
Baseline Anxiety	0.1	0.2	0.8	0.9	-0.1	-0.0	-0.2	-0.3
Tail length	1.1	4.2	6.3	-2.5	-1.8	2.1	-1.9	-1.9
Length with tail	2.4	10.3	12.9	-3.6	-2.8	3.3	-3.1	-3.1
Length without tail	3.1	9.9	10.9	-2.8	-3.1	3.2	-3.3	-3.3
Times rat made contact with spout	2.8	3.2	4.0	1.1	1.9	-1.8	2.0	2.0
Lifetime Intake	0.1	0.1	0.3	-0.6	-0.2	0.2	-0.0	-0.0
Liver weight, left	2.0	3.2	3.9	-1.7	-2.0	1.8	-1.8	-1.8
Liver weight, right	2.8	4.9	5.5	-1.9	-2.3	2.2	-2.3	-2.3
Locomotor activity	0.1	0.2	0.3	-0.6	-0.6	0.4	-0.3	-0.3
Locomotor testing distance	0.0	0.1	0.2	0.5	-0.2	0.0	-0.2	-0.2
Locomotor testing rearing	0.7	1.3	1.5	-1.0	-1.2	1.2	-1.2	-1.2
Locomotion in novel chamber	0.4	0.5	0.7	0.9	0.8	-0.7	0.6	0.6
Locomotion in novel chamber post-restriction	1.6	2.7	2.8	-1.6	-1.6	1.7	-1.7	-1.7
Fecal boli incidents, locomotor time 1	0.0	0.0	0.1	-0.3	-0.3	0.2	-0.1	-0.1
Change in fecal boli incidents, locomotor task	1.1	1.1	1.6	1.2	-0.7	0.7	-1.2	-1.3
Time >=10cm from walls, locomotor time 1	1.4	1.5	2.5	-0.1	-1.2	1.2	-1.5	-1.6
Bouts of movement, locomotor time 1	0.2	0.2	0.3	0.2	0.4	-0.4	0.5	0.5
Total resting periods, locomotor time 1	0.0	0.0	0.1	-0.3	0.2	-0.1	0.2	0.3
Rest time, locomotor task time 1	0.1	0.1	0.2	0.2	-0.3	0.3	-0.4	-0.5
Distance moved, locomotor task time 1	0.1	0.1	0.1	-0.4	-0.2	0.3	-0.3	-0.3
Vertical activity count, locomotor time 1	0.3	0.6	0.7	-0.9	-0.8	0.8	-0.8	-0.8
Time >=10cm from walls, locomotor time 2	3.9	5.8	8.7	-0.6	-2.5	2.4	-2.9	-3.0
Bouts of movement, locomotor time 2	0.1	0.1	0.3	-0.6	-0.2	0.3	-0.2	-0.1
Total resting periods, locomotor time 2	0.0	0.0	0.0	0.0	0.2	-0.2	0.2	0.2
Rest time, locomotor task time 2	0.0	0.0	0.1	0.3	0.0	0.0	-0.1	-0.1
Distance moved, locomotor task time 2	2.1	2.6	3.0	-1.3	-1.5	1.6	-1.7	-1.7
Vertical activity count, locomotor time 2	0.8	1.1	1.6	-0.7	-1.0	1.1	-1.2	-1.3
Light reinforcement 1	1.3	3.1	3.6	-1.4	-1.8	1.8	-1.9	-1.9
Light reinforcement 2	2.3	3.5	3.9	-2.0	-1.9	1.9	-1.8	-1.8
Bone: marrow area	3.5	7.6	8.7	-2.5	-2.9	2.8	-2.8	-2.8
Bone: maximum diameter	0.3	0.6	0.9	-0.3	-0.9	0.8	-0.9	-0.9
Bone: maximum force	1.3	2.3	2.8	-1.3	-1.7	1.5	-1.6	-1.5
Bone: maximum moment	1.0	1.8	2.4	-1.1	-1.5	1.3	-1.3	-1.3
Mean time between licks in bursts	0.5	1.2	1.2	1.0	1.1	-1.1	1.1	1.1
Mean num. licks in bursts	0.2	0.3	0.4	0.1	0.5	-0.5	0.6	0.6
Cd content in liver	0.0	0.0	0.1	-0.3	-0.1	0.1	0.0	0.0
Co content in liver	1.9	2.2	2.6	-1.2	-1.5	1.5	-1.6	-1.6
Cu content in liver	3.2	3.8	4.1	1.9	2.0	-2.0	1.9	1.9
Fe content in liver	1.9	2.3	2.9	-1.7	-1.4	1.5	-1.5	-1.5
K content in liver	0.9	0.9	1.2	1.1	1.0	-0.9	0.8	0.8
Mg content in liver	1.2	1.3	2.3	1.5	1.1	-1.1	0.9	0.9
Mn content in liver	0.0	0.0	0.0	0.2	0.0	0.0	-0.1	-0.1
Na content in liver	0.2	0.2	0.5	0.3	0.7	-0.4	0.4	0.4
Rb content in liver	0.0	0.0	0.0	0.2	-0.0	-0.0	-0.0	-0.0
Se content in liver	1.7	2.0	2.2	1.5	1.5	-1.4	1.3	1.3
Sr content in liver	0.0	0.0	0.0	0.1	0.2	-0.1	0.1	0.1
Zn content in liver	0.6	0.7	1.8	1.3	0.4	-0.8	0.6	0.6
Bone: minimum diameter	1.4	2.5	3.3	-0.6	-1.8	1.6	-1.8	-1.8
Time in familiar zone, hab. session 1	0.0	0.0	0.1	-0.3	-0.0	-0.0	0.1	0.2
Time in novel zone, hab. session 1	0.3	0.3	0.4	-0.2	-0.6	0.5	-0.6	-0.6
Total zone transitions, hab. session 1	3.0	4.2	5.1	1.9	2.2	-2.1	2.1	2.0
Total locomotion distance, hab. session 1	2.0	2.9	3.2	1.7	1.8	-1.7	1.7	1.6
Locomotion velocity, hab. session 1	2.0	2.8	3.2	1.8	1.8	-1.7	1.6	1.6
Time in familiar zone, hab. session 2	1.3	1.3	1.5	1.1	1.1	-1.2	1.2	1.2
Time in novel zone, hab. session 2	1.8	1.8	2.3	-1.5	-1.4	1.3	-1.3	-1.2
Total zone transitions, hab. session 2	0.4	0.5	0.7	0.8	0.7	-0.7	0.7	0.7
Total locomotion distance, hab. session 2	2.3	3.0	3.2	1.8	1.7	-1.8	1.7	1.7
Locomotion velocity, hab. session 2	2.9	3.9	4.1	2.0	2.0	-2.0	2.0	1.9
Novel to familiar place preference ratio	0.3	0.3	0.5	0.0	-0.5	0.5	-0.7	-0.7
Novelty place preference	0.2	0.2	0.4	0.0	-0.4	0.5	-0.6	-0.7
Time in novel zone, NPP test	0.3	0.3	0.5	-0.2	-0.6	0.6	-0.7	-0.7
Total zone transitions, NPP test	1.5	2.1	2.6	1.6	1.3	-1.5	1.4	1.4
Total locomotion distance, NPP test	1.3	1.8	2.5	1.6	1.2	-1.4	1.3	1.3
Locomotion velocity, NPP test	2.1	3.0	4.2	2.0	1.6	-1.7	1.6	1.6
Intraocular pressure	1.5	2.2	3.8	-2.0	-1.6	1.4	-1.2	-1.1
Delta distance traveled before/after self-admin	0.6	0.6	1.1	1.0	0.8	-0.8	0.7	0.7
Delta ambulatory time before/after self-admin	0.5	0.6	0.8	0.8	0.9	-0.7	0.7	0.7
Parametrial fat weight	4.3	10.0	18.0	-4.2	-3.0	3.1	-2.7	-2.6
Pavlov. Cond. lever latency	0.4	0.5	0.7	-0.8	-0.8	0.7	-0.7	-0.7
Pavlov. Cond. magazine entry latency	0.3	0.3	0.5	0.5	0.4	-0.6	0.7	0.7
Pavlov. Cond. change in total contacts	0.7	0.7	1.0	-1.0	-0.8	0.8	-0.8	-0.7
Pavlov. Cond. index score	0.1	0.1	0.2	0.4	0.1	-0.3	0.3	0.3
Pavlov. Cond. latency score	0.0	0.1	0.2	0.5	0.0	-0.2	0.1	0.1
Pavlov. Cond. lever contacts	0.1	0.1	0.3	0.5	0.3	-0.3	0.2	0.2
Pavlov. Cond. magazine entry number	0.7	0.8	1.0	-1.0	-0.7	1.0	-0.9	-0.9
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	-0.1	0.4	-0.2	0.2	0.2
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.1	0.4	0.1	-0.3	0.2	0.3
Pavlov. Cond. response bias	0.7	0.8	0.9	0.8	0.9	-0.9	0.9	1.0
Pavlov. Cond. lever latency	1.5	2.1	3.1	-0.7	-1.3	1.5	-1.7	-1.8
Pavlov. Cond. magazine entry latency	0.3	0.4	1.0	-1.0	-0.5	0.5	-0.4	-0.3
Pavlov. Cond. change in total contacts	0.7	1.2	1.7	0.5	1.0	-1.1	1.3	1.3
Pavlov. Cond. index score	0.3	0.4	0.6	-0.1	0.5	-0.6	0.8	0.8
Pavlov. Cond. latency score	0.2	0.2	0.4	-0.1	0.4	-0.5	0.6	0.7
Pavlov. Cond. lever contacts	1.2	1.6	2.5	0.6	1.2	-1.3	1.5	1.6
Pavlov. Cond. magazine entry number	0.1	0.1	0.5	0.7	0.3	-0.2	0.1	0.0
Pavlov. Cond. intertrial magazine entries	0.5	0.8	0.8	0.9	0.9	-0.9	0.9	0.9
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.4	-0.2	0.4	-0.5	0.6	0.7
Pavlov. Cond. response bias	0.5	0.7	1.2	0.0	0.7	-0.8	1.1	1.1
Time in closed arm before self-admin	0.7	0.9	2.0	1.4	0.9	-0.9	0.7	0.7
Time in closed arm after self-admin	0.3	0.4	1.7	1.3	-0.1	-0.1	-0.2	-0.3
Time in open arm before self-admin	0.1	0.1	0.1	-0.1	0.3	-0.3	0.4	0.4
Time in open arm after self-admin	0.8	0.9	1.3	-0.4	1.0	-0.8	1.1	1.2
Bone: periosteal estimation	1.8	3.8	4.6	-1.5	-2.1	2.0	-2.1	-2.1
Bone: periosteal perimeter	0.7	1.2	1.6	-0.6	-1.2	1.1	-1.2	-1.2
Bone: post-yield work	0.2	0.4	0.4	-0.5	-0.7	0.6	-0.6	-0.6
Progressive ratio test 1 active lever presses	0.1	0.1	0.3	0.5	-0.1	-0.0	-0.1	-0.2
Progressive ratio test 1 breakpoint	0.1	0.1	0.5	0.7	0.1	-0.1	-0.0	-0.1
Progressive ratio test 1 inactive lever presses	0.4	0.6	0.8	-0.9	-0.7	0.8	-0.7	-0.7
Progressive ratio test 2 active lever presses	0.0	0.0	0.1	-0.3	-0.2	0.1	0.0	0.0
Progressive ratio test 2 breakpoint	0.0	0.0	0.1	-0.3	-0.1	0.0	0.1	0.1
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.1	-0.2	0.2	-0.1	0.3	0.3
Incentive Sensitization - Responses	0.6	0.8	1.2	0.4	0.9	-0.9	1.1	1.1
Incentive Sensitization - Breakpoint	0.3	0.4	0.8	0.0	0.6	-0.7	0.8	0.9
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	0.5	0.6	-0.4	0.4	0.4
Progressive ratio	2.8	4.4	8.1	-2.8	-1.9	2.0	-1.8	-1.7
Food seeking constrained by brief footshock	0.1	0.1	0.1	0.2	0.2	-0.3	0.3	0.3
Seeking ratio, punishment vs. effort	2.1	3.0	7.2	2.7	1.4	-1.6	1.3	1.3
Retroperitoneal fat weight	1.2	5.1	6.3	-2.5	-2.3	2.2	-2.1	-2.1
Reaction time number correct	0.6	1.2	3.2	-1.8	-0.9	1.0	-0.7	-0.7
Reaction time mean minus median	0.3	0.6	2.6	-1.6	-0.4	0.5	-0.2	-0.2
Reaction time mean minus median AUC	0.2	0.6	2.4	-1.5	-0.6	0.6	-0.3	-0.2
Reaction time num false alarms	0.2	0.3	0.5	0.3	0.7	-0.5	0.6	0.6
Reaction time num false alarms AUC	0.9	1.4	1.8	1.1	1.3	-1.2	1.2	1.1
Reaction time trials correct on left	0.6	1.2	3.2	-1.8	-0.9	1.0	-0.7	-0.7
Reaction time trials on left	0.6	1.1	3.1	-1.8	-0.9	1.0	-0.7	-0.6
Reaction time mean	0.3	0.5	0.8	-0.9	-0.7	0.6	-0.6	-0.5
Reaction time mean AUC	0.7	1.1	2.0	-1.4	-1.0	1.0	-0.8	-0.8
Median of all reaction times	0.3	0.5	0.6	-0.6	-0.8	0.7	-0.7	-0.7
Reaction time omissions	0.1	0.2	0.8	-0.9	-0.1	0.3	-0.1	-0.1
Reaction time false alarm rate	2.0	2.7	4.3	2.1	1.7	-1.6	1.4	1.4
Reaction time premature initiation rate	0.3	0.3	0.9	1.0	0.6	-0.5	0.3	0.3
Reaction time premature initiations	0.0	0.0	0.0	-0.1	-0.0	0.2	-0.2	-0.2
Std. dev. reaction times	0.1	0.2	0.9	-0.9	-0.2	0.2	-0.1	-0.0
Reaction time trials completed	0.6	1.1	3.1	-1.8	-0.9	1.0	-0.7	-0.6
Reaction time trials AUC	0.6	1.2	3.2	-1.8	-0.9	1.0	-0.7	-0.6
Run reversals in cocaine runway, females	0.3	0.3	1.0	-1.0	-0.5	0.5	-0.3	-0.3
Run reversals in cocaine runway, males	1.1	1.1	5.1	-2.3	-0.2	0.5	-0.1	0.0
Latency to leave start box in cocaine runway	1.8	2.0	7.5	2.7	1.0	-1.0	0.5	0.4
Latency to leave start box in cocaine runway, F	1.2	1.3	5.5	2.3	0.6	-0.8	0.4	0.3
Latency to leave start box in cocaine runway, M	0.3	0.3	1.3	1.1	0.5	-0.2	-0.0	-0.1
Std. dev. time between licks in bursts	0.5	0.7	0.9	0.8	-0.9	0.5	-0.9	-0.9
Total sessions with >9 infusions	0.0	0.0	0.0	0.1	-0.0	-0.1	0.1	0.1
Short access day 1 total inactive lever presses	0.1	0.1	0.5	-0.7	-0.2	0.3	-0.2	-0.2
Short access day 10 total inactive lever presses	0.2	0.6	0.7	0.4	0.9	-0.7	0.8	0.8
Short access day 1 total infusions	0.3	0.4	0.8	0.9	0.6	-0.6	0.5	0.5
Short access day 10 total infusions	0.2	0.2	0.5	-0.7	0.3	-0.2	0.5	0.6
Short access total infusions	0.0	0.0	0.0	-0.1	-0.0	0.0	0.0	0.0
Short access day 1 locomotion	0.3	0.3	1.3	1.1	0.3	-0.4	0.2	0.2
Short access day 10 total locomotion	0.5	0.9	4.2	2.1	0.4	-0.5	0.1	-0.0
Short access total locomotion	0.3	0.3	1.6	1.3	0.1	-0.1	-0.1	-0.2
One hour access (0.3 mA shock)	2.3	2.6	2.8	1.5	1.6	-1.6	1.7	1.7
Compulsive drug intake	3.1	3.7	7.8	2.8	1.8	-1.8	1.5	1.4
One hour access (shock baseline)	0.3	0.5	2.1	-1.4	-0.1	0.1	0.3	0.3
Social response proportion	0.1	0.1	0.5	0.7	-0.1	-0.0	-0.2	-0.2
Social responses	0.1	0.2	0.8	0.9	0.0	-0.2	0.0	-0.0
Social time	0.2	0.2	0.3	0.3	0.6	-0.5	0.5	0.5
Soleus weight	0.3	1.0	1.6	0.1	-1.0	0.9	-1.2	-1.3
Bone: stiffness	1.1	1.9	2.2	-1.3	-1.5	1.3	-1.3	-1.3
Tibialis anterior weight	0.7	2.3	3.1	1.7	1.5	-1.5	1.4	1.4
Time to tail flick, vehicle, before self-admin	3.1	3.2	8.4	-2.9	-1.5	1.6	-1.3	-1.2
Time to tail flick, vehicle, after self-admin	0.6	0.8	1.3	1.1	0.8	-0.9	0.8	0.7
Time to tail flick, test, before self-admin	0.3	0.4	0.6	0.0	0.6	-0.6	0.7	0.8
Time to tail flick, test, after self-admin	0.6	0.6	2.5	-1.6	0.0	-0.0	0.5	0.6
Delta time to tail flick, vehicle, before/after SA	2.8	2.6	4.5	2.1	1.3	-1.6	1.5	1.4
Delta time to tail flick, test, before/after SA	1.1	1.1	2.2	-1.5	-1.0	1.0	-0.8	-0.8
Tibia length	2.5	7.0	7.9	-2.8	-2.5	2.7	-2.6	-2.6
Ambulatory time before self-admin	0.1	0.2	0.2	-0.5	-0.4	0.4	-0.4	-0.4
Ambulatory time after self-admin	0.1	0.1	0.2	-0.1	0.4	-0.2	0.2	0.2
Bone: tissue strength	0.0	0.0	0.0	-0.1	-0.1	0.1	-0.1	-0.1
Total heroin consumption	0.8	1.0	1.4	0.4	1.2	-1.0	1.1	1.1
Bone: trabecular number	0.8	1.3	1.7	0.5	1.2	-1.1	1.3	1.3
Bone: trabecular spacing	1.7	2.2	2.6	-1.1	-1.6	1.5	-1.6	-1.6
Bone: trabecular thickness	0.6	0.7	2.1	-1.4	-0.6	0.7	-0.5	-0.5
Bone: trabecular tissue density	0.1	0.1	0.5	-0.7	0.0	0.1	0.0	0.0
Water consumed over 24 hours	1.1	1.5	2.5	1.6	1.1	-1.2	1.0	1.0
Number of responses in last shaping day	1.8	1.9	8.8	3.0	0.5	-0.7	0.1	-0.0