Hub : Genes

LOC120098863

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC120098863 0.22 0.14 8.3e-05 0.03 0.01 0.01 0.02 4.6e-04 2.9e-02 1.4e-02 3.4e-03
2 IL gene expression LOC120098863 0.13 0.1 5.7e-03 0.05 0.06 0.01 0.03 2.6e-02 1.7e-02 1.6e-01 8.0e-02
3 PL gene expression LOC120098863 0.06 0.04 1.9e-09 0.08 0.09 0.08 0.08 2.4e-09 1.2e-09 2.9e-09 2.6e-09
4 BLA gene expression LOC120098863 0.05 0.04 4.1e-03 0.01 0.04 0.02 0.01 6.4e-02 4.8e-03 3.0e-02 5.0e-02
5 OFC gene expression LOC120098863 0.33 0.25 5.7e-04 0.12 0.1 0.11 0.12 7.4e-04 1.9e-03 1.7e-03 9.0e-04
6 NAcc gene expression LOC120098863 0.07 0.06 6.5e-08 0.07 0.06 0.06 0.06 4.4e-08 8.1e-08 6.3e-08 8.8e-08
7 pVTA gene expression LOC120098863 0.17 0.15 4.8e-03 0.01 0.03 0.01 0.01 1.1e-01 2.1e-02 1.3e-01 7.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.50.81.00.8-0.9-0.9-0.91.00.8-0.7
Area under the delay curve0.70.71.8-0.30.91.00.8-0.4-0.81.3
BMI with tail1.65.26.0-1.82.42.42.3-2.3-2.32.4
BMI without tail1.12.32.6-1.51.61.61.6-1.6-1.41.5
Body weight6.025.128.5-4.65.15.25.1-4.6-5.15.3
Weight adjusted by age0.80.92.1-0.21.01.11.0-0.4-1.01.5
Bone surface0.00.00.00.0-0.00.00.00.2-0.10.2
Bone volume0.00.00.2-0.00.10.20.20.0-0.20.4
Breakpoint value in progressive ratio session0.30.31.30.3-0.4-0.6-0.40.20.5-1.1
Number of licking bursts0.50.60.80.7-0.8-0.8-0.80.60.7-0.9
Context. condit. distance diff. score0.40.50.60.8-0.7-0.6-0.70.70.7-0.5
Locomotion velocity, session 10.90.92.11.5-0.9-0.8-0.91.20.80.1
Locomotion distance, session 13.44.34.82.2-2.2-2.1-2.22.22.1-1.6
Locomotion velocity, session 20.30.40.80.9-0.6-0.6-0.60.40.6-0.6
Locomotion distance, session 20.91.21.41.2-1.1-1.1-1.11.21.1-0.8
Locomotion velocity, session 30.60.71.5-0.40.70.80.7-0.9-0.91.2
Locomotion distance, session 30.30.30.70.8-0.6-0.5-0.60.40.5-0.1
Stereotopy head waving bouts, day 31.92.32.4-1.31.51.51.5-1.5-1.51.5
Stereotopy head waving duration, day 30.10.10.3-0.10.30.30.3-0.1-0.30.5
Locomotion velocity, session 70.10.10.40.5-0.1-0.1-0.10.50.10.7
Locomotion distance, session 70.91.22.11.4-1.0-1.0-1.11.51.0-0.2
Stereotopy head waving bouts, day 70.50.61.0-0.70.70.80.7-0.8-0.81.0
Stereotopy head waving duration, day 71.41.72.0-1.11.21.31.3-1.4-1.31.4
Locomotion velocity, session 80.00.00.10.2-0.1-0.1-0.10.20.10.2
Locomotion distance, session 80.91.31.41.0-1.2-1.2-1.21.11.2-1.0
Degree of sensitization distance0.00.00.2-0.00.0-0.1-0.10.40.1-0.2
Degree of sensitization stereotypy0.00.00.10.00.00.10.1-0.3-0.10.3
Conditioned locomotion2.93.44.2-2.01.91.82.0-2.0-1.81.2
Cocaine response after cond. corrected0.50.60.9-0.90.80.80.7-0.8-0.70.5
Cocaine response after cond. not corrected0.50.61.1-1.00.80.80.7-0.8-0.70.5
Cocaine response before conditioning0.00.00.0-0.10.10.10.10.0-0.00.2
Saline control response0.60.71.0-0.91.00.90.9-0.8-0.80.5
Bone: connectivity density0.40.60.90.8-0.8-0.8-0.80.90.7-0.6
Bone: cortical apparent density0.10.21.1-1.00.20.10.2-0.2-0.2-0.4
Bone: cortical area0.20.31.1-0.10.50.60.4-0.1-0.41.1
Bone: cortical porosity0.10.20.70.5-0.1-0.0-0.10.30.00.8
Bone: cortical porosity0.10.20.60.5-0.2-0.1-0.20.50.10.8
Bone: cortical thickness0.20.30.60.7-0.5-0.4-0.50.80.50.3
Bone: cortical thickness0.00.00.0-0.00.10.10.1-0.1-0.10.0
Bone: cortical tissue density0.20.21.2-1.10.30.20.3-0.3-0.3-0.3
Condit. Reinf. active minus inactive responses1.11.22.91.7-1.0-0.9-1.01.21.0-0.6
Condit. Reinf. active-inactive response ratio0.10.10.20.5-0.2-0.2-0.20.20.3-0.5
Condit. Reinf. active responses0.30.31.31.1-0.4-0.4-0.40.70.4-0.1
Condit. Reinf. inactive responses0.10.20.30.6-0.4-0.4-0.30.40.3-0.1
Incentive salience index mean0.50.61.91.4-0.6-0.6-0.60.80.6-0.1
Condit. Reinf. lever presses0.20.20.91.0-0.3-0.2-0.30.40.20.3
Condit. Reinf. active minus inactive responses0.60.70.90.8-0.9-0.9-0.90.70.8-0.9
Condit. Reinf. active-inactive response ratio0.20.20.50.2-0.5-0.6-0.50.30.4-0.7
Condit. Reinf. active responses0.60.80.90.9-0.9-0.9-0.90.90.9-0.8
Condit. Reinf. inactive responses0.00.00.10.00.20.20.1-0.1-0.10.4
Condit. Reinf. lever presses3.95.25.72.2-2.2-2.3-2.32.42.4-2.2
Condit. Reinf. lever reinforcers received1.41.92.31.5-1.4-1.4-1.41.51.4-1.2
Conditioned reinforcement - actives0.70.72.60.00.70.80.60.0-0.81.6
Conditioned reinforcement - inactives0.10.10.20.1-0.3-0.3-0.30.10.3-0.4
Conditioned locomotion0.60.82.80.10.80.90.70.2-0.81.7
Patch foraging indifference point 0 sec0.40.71.4-1.20.70.70.7-1.1-0.70.5
Patch foraging indifference point AUC0.00.00.00.1-0.2-0.1-0.10.10.1-0.2
Delay disc. indifference point, 0s delay0.10.10.30.40.20.20.10.4-0.10.5
Delay disc. indifference point, 16s delay0.20.20.9-0.10.40.50.3-0.1-0.41.0
Delay disc. indifference point, 2s delay0.30.30.91.0-0.4-0.4-0.50.90.5-0.1
Delay disc. indifference point, 24s delay2.22.24.9-0.91.51.61.4-0.8-1.52.2
Delay disc. indifference point, 4s delay0.90.91.3-0.71.11.11.0-0.9-0.91.0
Delay disc. indifference point, 8s delay1.51.63.1-0.51.31.41.3-0.7-1.31.7
Indifference point function ln k0.10.20.30.6-0.4-0.4-0.40.40.4-0.0
Indifference point function log k0.10.20.30.6-0.4-0.4-0.40.40.4-0.0
Patch foraging total patch changes 0 sec0.40.61.3-1.10.70.60.7-1.0-0.60.5
Patch foraging total patch changes 12 sec0.00.10.2-0.3-0.1-0.1-0.1-0.40.1-0.3
Patch foraging total patch changes 18 sec0.81.02.0-1.41.00.91.0-1.3-0.90.4
Patch foraging total patch changes 24 sec0.30.40.90.2-0.6-0.7-0.60.30.8-0.9
Patch foraging total patch changes 6 sec0.10.20.6-0.80.30.20.3-0.6-0.1-0.1
Patch foraging time to switch 0 sec0.91.31.8-1.01.31.31.3-1.1-1.10.8
Patch foraging water rate 0 sec0.10.20.40.1-0.6-0.6-0.60.30.4-0.4
Patch foraging water rate 12 sec0.10.20.20.1-0.5-0.5-0.40.20.4-0.4
Patch foraging water rate 18 sec0.40.50.80.1-0.7-0.8-0.70.60.8-0.9
Patch foraging water rate 24 sec0.30.40.90.1-0.7-0.7-0.70.20.8-1.0
Patch foraging water rate 6 sec0.10.20.30.1-0.5-0.5-0.50.30.5-0.4
Seeking ratio, delayed vs. immediate footshock0.30.31.2-1.10.20.10.2-0.8-0.2-0.6
Distance traveled before self-admin1.41.53.6-1.81.00.91.1-1.9-0.90.1
Distance traveled after self-admin0.60.72.1-1.30.40.30.5-1.4-0.4-0.8
Extensor digitorum longus weight0.20.70.80.7-0.8-0.9-0.80.70.9-0.9
Bone: elastic displacement0.10.10.30.4-0.3-0.2-0.30.50.20.5
Bone: elastic work0.10.10.30.30.00.1-0.00.40.00.6
Bone: endosteal estimation3.06.67.8-2.42.82.72.7-2.4-2.62.3
Bone: endosteal perimeter1.73.54.1-2.02.01.91.9-2.0-1.91.3
Epididymis fat weight1.33.03.6-1.61.81.81.8-1.4-1.81.9
Delta time in closed arm before/after self-admin1.51.51.6-1.21.21.21.2-1.2-1.31.2
Delta time in open arm before/after self-admin1.00.91.41.2-0.9-0.9-0.91.21.0-0.7
Diff in mean of infusions in LGA sessions0.80.91.80.5-0.9-1.0-1.00.71.0-1.4
Delay discount exponential model param0.60.61.60.3-0.8-0.9-0.70.40.7-1.3
Extinction: sum of active levers before priming0.20.20.30.2-0.5-0.5-0.40.30.6-0.6
Active lever presses in extinction session 60.10.10.30.20.10.10.00.6-0.10.3
Bone: final force3.96.47.1-2.42.72.72.6-2.3-2.62.5
Bone: final moment3.15.15.9-2.02.42.42.3-1.9-2.32.3
Food consumed during 24 hour testing period0.40.50.8-0.80.80.70.8-0.9-0.6-0.1
Glucose0.10.20.50.6-0.1-0.0-0.20.50.20.7
Heart weight2.43.44.11.8-2.0-1.9-2.02.01.8-1.3
Delay discount hyperbolic model param0.30.31.00.1-0.6-0.7-0.50.20.5-1.0
Intermittent access intake day 1-15 change1.01.01.2-1.11.01.01.1-1.1-1.10.8
Intermittent access intake escalation1.71.72.1-1.41.31.21.3-1.4-1.31.0
Intermittent access intake escalation 20.00.00.1-0.1-0.1-0.10.1-0.1-0.30.1
Intermitt. access day 1 inactive lever presses0.10.10.4-0.5-0.3-0.3-0.2-0.30.2-0.6
Intermitt. access day 15 inactive lever presses1.71.82.5-1.51.31.31.4-1.6-1.41.0
Intermitt. access escalation Index0.40.40.80.5-0.6-0.6-0.60.10.5-0.9
Intermittent access day 1 total infusions0.80.92.71.6-0.7-0.5-0.71.30.60.4
Intermittent access day 15 total infusions0.20.20.70.30.30.40.30.2-0.30.9
Intermittent access terminal intake (last 3 days)0.30.41.40.40.40.50.40.2-0.61.2
Intermittent access total infusions0.30.30.91.0-0.2-0.2-0.20.90.20.6
Intermittent access day 1 locomotion0.10.10.3-0.20.40.40.4-0.2-0.40.5
Intermittent access day 15 total locomotion5.35.76.3-2.42.42.42.5-2.4-2.42.1
Intermittent access total locomotion1.92.22.5-1.61.51.51.6-1.3-1.51.4
Intermittent access standard deviation1.01.11.8-1.31.01.01.1-1.1-1.10.6
Left kidney weight3.18.810.1-2.92.92.93.0-2.8-3.23.0
Right kidney weight3.810.711.9-3.03.33.43.4-3.0-3.53.3
Cocaine induced anxiety0.10.10.5-0.3-0.1-0.2-0.0-0.4-0.2-0.7
Post-drug Anxiety0.30.31.40.2-0.4-0.5-0.40.10.2-1.2
Baseline Anxiety0.40.40.60.7-0.5-0.6-0.60.80.7-0.5
Tail length1.33.95.2-2.31.91.92.0-1.7-1.92.1
Length with tail2.69.611.4-3.23.03.13.1-2.6-3.23.4
Length without tail1.94.14.8-1.92.02.02.0-1.8-2.22.2
Times rat made contact with spout2.62.93.31.6-1.8-1.8-1.71.61.7-1.8
Lifetime Intake0.20.30.90.70.10.20.10.6-0.21.0
Liver weight, left5.69.09.9-3.03.13.03.1-3.1-3.12.5
Liver weight, right2.94.86.5-2.32.12.12.2-2.6-2.21.7
Locomotor activity0.20.30.8-0.70.40.40.5-0.9-0.4-0.1
Locomotor testing distance0.00.10.3-0.10.0-0.00.0-0.30.1-0.5
Locomotor testing rearing1.01.52.2-1.51.31.21.3-1.4-1.10.5
Locomotion in novel chamber0.60.71.11.1-0.9-0.8-1.00.61.0-0.6
Locomotion in novel chamber post-restriction1.92.32.5-1.51.61.61.5-1.5-1.41.4
Fecal boli incidents, locomotor time 10.10.10.50.20.10.0-0.00.7-0.00.0
Change in fecal boli incidents, locomotor task0.10.10.40.20.30.30.2-0.6-0.20.1
Time >=10cm from walls, locomotor time 11.81.82.8-1.61.41.21.4-1.7-1.30.2
Bouts of movement, locomotor time 10.30.31.10.0-0.4-0.5-0.4-0.10.6-1.0
Total resting periods, locomotor time 10.10.10.4-0.2-0.1-0.2-0.1-0.30.3-0.6
Rest time, locomotor task time 10.10.10.5-0.20.30.30.30.1-0.40.7
Distance moved, locomotor task time 10.20.20.4-0.30.40.40.4-0.7-0.30.1
Vertical activity count, locomotor time 10.60.61.0-0.50.90.80.9-1.0-0.90.1
Time >=10cm from walls, locomotor time 24.44.66.1-1.22.42.52.3-1.3-2.42.4
Bouts of movement, locomotor time 20.50.51.4-1.20.50.40.5-1.1-0.3-0.4
Total resting periods, locomotor time 20.20.20.7-0.7-0.0-0.1-0.0-0.60.2-0.8
Rest time, locomotor task time 20.10.20.7-0.80.0-0.00.0-0.40.2-0.4
Distance moved, locomotor task time 22.02.43.7-0.61.71.71.7-1.0-1.71.9
Vertical activity count, locomotor time 21.31.42.3-0.51.31.31.3-0.6-1.51.4
Light reinforcement 12.13.95.3-2.22.02.02.0-2.3-1.91.2
Light reinforcement 22.53.44.2-2.11.91.91.9-1.9-1.81.2
Bone: marrow area3.26.98.0-2.52.82.82.8-2.5-2.72.3
Bone: maximum diameter0.30.50.9-0.60.70.80.7-0.5-0.70.9
Bone: maximum force1.42.43.9-1.11.61.71.6-1.1-1.62.0
Bone: maximum moment0.91.63.3-0.71.41.41.3-0.8-1.31.8
Mean time between licks in bursts0.40.61.00.5-0.9-0.9-0.80.50.8-1.0
Mean num. licks in bursts0.20.20.30.4-0.4-0.4-0.40.50.5-0.4
Cd content in liver1.11.22.1-0.71.11.21.1-0.7-1.21.4
Co content in liver2.22.63.1-1.31.71.71.7-1.8-1.61.4
Cu content in liver3.44.24.92.2-2.1-2.1-2.12.22.0-1.7
Fe content in liver4.65.57.6-2.12.32.42.3-2.2-2.42.8
K content in liver1.11.11.51.2-1.2-1.1-1.11.00.9-0.8
Mg content in liver3.03.15.62.4-1.8-1.7-1.81.71.6-1.2
Mn content in liver0.10.10.20.5-0.3-0.3-0.30.20.2-0.4
Na content in liver0.10.10.3-0.5-0.2-0.20.0-0.3-0.0-0.4
Rb content in liver0.10.10.30.30.40.40.30.1-0.30.6
Se content in liver2.73.35.32.3-2.0-1.9-1.91.61.7-1.3
Sr content in liver0.10.10.30.2-0.1-0.2-0.20.60.3-0.1
Zn content in liver0.40.51.90.10.70.70.5-0.1-0.41.4
Bone: minimum diameter1.01.82.1-1.21.41.41.3-1.2-1.31.4
Time in familiar zone, hab. session 10.10.10.20.4-0.1-0.1-0.20.30.10.3
Time in novel zone, hab. session 10.30.20.3-0.30.50.50.5-0.5-0.60.5
Total zone transitions, hab. session 12.33.34.12.0-2.0-1.9-1.91.51.8-1.4
Total locomotion distance, hab. session 11.72.43.01.7-1.7-1.6-1.71.11.6-1.2
Locomotion velocity, hab. session 11.62.32.91.7-1.7-1.6-1.61.11.5-1.1
Time in familiar zone, hab. session 21.31.44.2-0.2-1.1-1.2-1.10.51.2-2.0
Time in novel zone, hab. session 21.51.54.50.31.21.31.1-0.5-1.32.1
Total zone transitions, hab. session 20.30.40.80.1-0.7-0.7-0.70.10.7-0.9
Total locomotion distance, hab. session 22.02.74.11.0-1.8-1.8-1.80.91.8-2.0
Locomotion velocity, hab. session 22.43.34.71.1-2.0-2.0-2.01.02.0-2.2
Novel to familiar place preference ratio0.30.31.30.30.40.50.4-0.2-0.51.1
Novelty place preference0.30.31.10.20.40.50.4-0.3-0.51.1
Time in novel zone, NPP test0.30.31.20.20.50.60.5-0.3-0.61.1
Total zone transitions, NPP test1.62.32.61.5-1.6-1.6-1.61.51.6-1.2
Total locomotion distance, NPP test1.41.92.21.3-1.4-1.4-1.41.31.5-1.2
Locomotion velocity, NPP test2.02.83.31.5-1.8-1.8-1.81.51.8-1.6
Intraocular pressure1.21.62.0-1.01.31.41.3-1.3-1.21.4
Delta distance traveled before/after self-admin0.50.60.90.8-0.7-0.8-0.71.00.6-0.7
Delta ambulatory time before/after self-admin0.60.71.00.8-0.8-0.9-0.80.90.7-1.0
Parametrial fat weight2.54.97.7-2.62.12.12.2-2.8-2.01.3
Pavlov. Cond. lever latency0.91.24.2-2.00.90.70.9-1.2-0.6-0.5
Pavlov. Cond. magazine entry latency0.81.12.61.6-0.9-0.8-1.01.20.9-0.1
Pavlov. Cond. change in total contacts0.70.72.30.80.60.80.6-0.4-0.71.5
Pavlov. Cond. index score0.70.82.71.6-0.7-0.5-0.71.10.60.7
Pavlov. Cond. latency score0.50.72.21.5-0.6-0.4-0.61.00.50.7
Pavlov. Cond. lever contacts0.91.03.21.8-0.8-0.6-0.81.30.60.6
Pavlov. Cond. magazine entry number1.21.52.5-1.61.21.11.3-1.4-1.20.6
Pavlov. Cond. intertrial magazine entries0.00.00.10.2-0.0-0.00.00.3-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.70.93.21.8-0.6-0.4-0.71.10.50.9
Pavlov. Cond. response bias1.51.94.42.1-1.3-1.1-1.31.61.2-0.1
Pavlov. Cond. lever latency2.02.73.2-1.61.61.61.7-1.8-1.81.3
Pavlov. Cond. magazine entry latency0.20.20.5-0.70.50.40.4-0.3-0.50.4
Pavlov. Cond. change in total contacts1.21.71.91.2-1.3-1.3-1.41.31.4-1.3
Pavlov. Cond. index score0.40.50.80.7-0.7-0.7-0.80.90.8-0.6
Pavlov. Cond. latency score0.20.30.40.5-0.5-0.6-0.60.70.6-0.5
Pavlov. Cond. lever contacts1.41.92.21.4-1.3-1.3-1.41.51.5-1.1
Pavlov. Cond. magazine entry number0.00.10.10.4-0.3-0.2-0.20.20.2-0.0
Pavlov. Cond. intertrial magazine entries0.50.61.50.7-0.8-0.8-0.70.30.7-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.40.4-0.5-0.5-0.50.60.5-0.4
Pavlov. Cond. response bias0.71.01.41.1-1.0-1.0-1.11.21.0-0.6
Time in closed arm before self-admin0.30.40.50.6-0.7-0.7-0.70.60.6-0.6
Time in closed arm after self-admin0.10.10.30.10.20.20.2-0.2-0.30.5
Time in open arm before self-admin0.20.20.30.4-0.5-0.4-0.40.50.4-0.1
Time in open arm after self-admin1.82.02.81.4-1.4-1.4-1.41.71.5-1.2
Bone: periosteal estimation1.93.84.4-1.72.12.12.0-1.7-2.02.0
Bone: periosteal perimeter0.71.21.4-1.21.21.11.1-1.2-1.00.7
Bone: post-yield work0.20.30.9-0.10.50.50.5-0.0-0.60.9
Progressive ratio test 1 active lever presses0.10.10.40.5-0.2-0.1-0.20.60.20.1
Progressive ratio test 1 breakpoint0.10.10.40.6-0.2-0.2-0.20.60.30.1
Progressive ratio test 1 inactive lever presses0.80.91.1-0.91.01.01.0-0.9-1.00.8
Progressive ratio test 2 active lever presses0.00.00.00.10.00.00.00.10.00.0
Progressive ratio test 2 breakpoint0.00.00.00.2-0.1-0.1-0.10.20.1-0.0
Progressive ratio test 2 inactive lever presses0.10.10.30.5-0.4-0.4-0.30.30.2-0.2
Incentive Sensitization - Responses0.70.71.70.4-0.9-0.9-0.80.21.0-1.3
Incentive Sensitization - Breakpoint0.40.41.10.1-0.6-0.6-0.5-0.10.7-1.1
Sum of active levers in priming session hrs 5-60.70.71.71.2-0.7-0.7-0.71.30.50.0
Progressive ratio4.14.77.0-2.52.22.12.2-2.7-2.11.2
Food seeking constrained by brief footshock0.10.10.1-0.0-0.3-0.3-0.30.20.3-0.3
Seeking ratio, punishment vs. effort2.73.34.82.0-1.8-1.8-1.92.21.8-1.0
Retroperitoneal fat weight1.34.25.0-2.22.12.12.0-1.9-2.11.9
Reaction time number correct0.91.32.7-1.61.11.01.1-1.5-1.00.5
Reaction time mean minus median0.20.20.3-0.40.50.50.5-0.3-0.50.5
Reaction time mean minus median AUC0.20.20.60.00.40.50.4-0.0-0.40.8
Reaction time num false alarms0.10.20.6-0.5-0.3-0.3-0.2-0.30.3-0.7
Reaction time num false alarms AUC0.50.71.8-0.1-0.9-0.9-0.80.20.8-1.3
Reaction time trials correct on left0.91.32.7-1.61.11.01.1-1.5-1.00.5
Reaction time trials on left0.91.32.7-1.71.01.01.0-1.5-0.90.5
Reaction time mean0.10.20.5-0.10.50.50.40.1-0.40.7
Reaction time mean AUC0.40.51.1-0.30.80.90.8-0.2-0.71.0
Median of all reaction times0.20.20.4-0.20.50.60.5-0.0-0.40.6
Reaction time omissions0.10.20.6-0.70.20.20.3-0.6-0.2-0.4
Reaction time false alarm rate1.21.72.01.0-1.4-1.4-1.31.21.3-1.4
Reaction time premature initiation rate0.10.20.30.5-0.5-0.5-0.40.40.3-0.5
Reaction time premature initiations0.10.20.3-0.50.30.30.4-0.6-0.4-0.1
Std. dev. reaction times0.00.00.1-0.10.20.20.20.2-0.20.3
Reaction time trials completed0.91.32.7-1.71.01.01.0-1.5-0.90.5
Reaction time trials AUC0.91.32.7-1.71.01.01.1-1.5-0.90.5
Run reversals in cocaine runway, females0.30.31.10.70.40.40.30.5-0.31.0
Run reversals in cocaine runway, males0.30.30.8-0.20.40.40.5-0.4-0.70.9
Latency to leave start box in cocaine runway0.60.60.70.8-0.8-0.8-0.80.80.7-0.7
Latency to leave start box in cocaine runway, F0.50.60.70.6-0.8-0.8-0.80.80.7-0.7
Latency to leave start box in cocaine runway, M0.00.00.00.2-0.1-0.1-0.10.00.1-0.0
Std. dev. time between licks in bursts0.10.10.2-0.10.20.30.2-0.3-0.20.4
Total sessions with >9 infusions0.10.10.30.50.10.1-0.00.5-0.00.4
Short access day 1 total inactive lever presses0.10.10.40.6-0.3-0.2-0.20.60.00.3
Short access day 10 total inactive lever presses0.60.71.8-1.30.20.10.3-1.3-0.3-0.9
Short access day 1 total infusions1.31.42.71.6-1.1-1.0-1.11.51.0-0.3
Short access day 10 total infusions0.00.00.00.1-0.1-0.1-0.10.20.0-0.1
Short access total infusions0.20.20.50.7-0.00.0-0.10.7-0.10.7
Short access day 1 locomotion0.10.10.3-0.1-0.3-0.3-0.30.10.3-0.5
Short access day 10 total locomotion0.60.62.0-0.5-0.7-0.8-0.6-0.20.8-1.4
Short access total locomotion0.10.10.4-0.70.1-0.00.1-0.4-0.1-0.4
One hour access (0.3 mA shock)0.70.81.00.9-1.0-1.0-1.01.00.9-0.6
Compulsive drug intake2.93.03.61.6-1.8-1.8-1.81.91.7-1.6
One hour access (shock baseline)0.30.40.9-0.20.60.60.6-0.3-0.61.0
Social response proportion0.00.00.00.0-0.0-0.0-0.10.10.00.1
Social responses0.10.20.7-0.3-0.2-0.3-0.3-0.30.3-0.8
Social time0.20.20.9-0.0-0.4-0.4-0.3-0.20.4-1.0
Soleus weight0.20.60.9-0.50.80.80.8-0.7-0.81.0
Bone: stiffness1.11.72.1-0.81.41.51.4-1.2-1.31.4
Tibialis anterior weight0.92.93.81.5-1.7-1.8-1.71.41.8-2.0
Time to tail flick, vehicle, before self-admin3.03.06.4-1.91.61.61.7-2.5-1.50.9
Time to tail flick, vehicle, after self-admin0.20.20.50.1-0.3-0.4-0.30.20.5-0.7
Time to tail flick, test, before self-admin0.40.41.0-1.0-0.2-0.2-0.1-0.90.2-0.9
Time to tail flick, test, after self-admin0.00.00.0-0.20.10.10.1-0.2-0.10.0
Delta time to tail flick, vehicle, before/after SA2.02.04.61.5-1.2-1.2-1.32.21.3-0.6
Delta time to tail flick, test, before/after SA1.21.12.1-0.31.21.21.1-0.4-1.11.5
Tibia length2.98.18.8-2.92.92.92.9-2.9-3.02.5
Ambulatory time before self-admin0.90.92.5-1.50.70.60.8-1.6-0.60.0
Ambulatory time after self-admin0.40.51.6-0.8-0.2-0.3-0.1-0.90.2-1.3
Bone: tissue strength0.00.00.1-0.10.0-0.0-0.00.30.10.0
Total heroin consumption0.30.30.90.3-0.6-0.7-0.50.20.5-1.0
Bone: trabecular number0.91.41.61.2-1.3-1.2-1.21.31.2-0.9
Bone: trabecular spacing1.82.42.6-1.61.61.61.6-1.6-1.51.2
Bone: trabecular thickness0.40.41.2-0.30.60.70.6-0.3-0.71.1
Bone: trabecular tissue density0.10.10.4-0.40.20.30.3-0.1-0.30.6
Water consumed over 24 hours1.41.72.41.2-1.3-1.3-1.31.11.3-1.5
Number of responses in last shaping day2.12.25.42.3-1.3-1.1-1.32.21.00.4