Hub : Genes

LOC120098827

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC120098827 0.25 0.09 0.0e+00 0.23 0.23 0.22 0.23 9.2e-26 2.8e-26 1.1e-25 8.2e-27
2 Liver gene expression LOC120098827 0.1 0.06 1.1e-04 0.03 0.02 0.03 0.02 6.6e-04 2.0e-03 8.2e-04 5.4e-03
3 PL gene expression LOC120098827 0.26 0.09 0.0e+00 0.24 0.23 0.24 0.25 1.3e-25 3.2e-25 5.6e-26 7.9e-27
4 BLA gene expression LOC120098827 0.4 0.12 1.8e-12 0.2 0.2 0.16 0.2 4.9e-11 7.3e-11 3.9e-09 1.0e-10
5 Brain gene expression LOC120098827 0.07 0.04 9.3e-05 0.04 0.05 0.02 0.04 1.2e-04 3.1e-05 5.1e-03 2.9e-04
6 pVTA gene expression LOC120098827 0.36 0.12 2.7e-08 0.16 0.19 0.19 0.17 1.7e-07 1.0e-08 1.2e-08 4.9e-08
7 RMTg gene expression LOC120098827 0.26 0.12 2.4e-04 0.11 0.12 0.09 0.11 6.9e-04 4.4e-04 2.6e-03 6.3e-04
8 Adipose isoform ratio XR_005497412.1 0.03 0.02 5.4e-04 0.01 0.02 0.02 0.01 1.7e-02 1.0e-03 5.8e-03 8.7e-03
9 Adipose intron excision ratio chr20_3179132_3179736 0.11 0.06 1.2e-03 -0 -0 -0 -0 4.6e-01 9.2e-01 6.9e-01 7.0e-01
10 Adipose intron excision ratio chr20_3179132_3179862 0.11 0.06 1.2e-03 -0 -0 -0 -0 4.6e-01 8.7e-01 7.3e-01 6.6e-01
11 Adipose gene expression LOC120098827 0.51 0.21 0.0e+00 0.3 0.34 0.35 0.34 4.9e-34 1.5e-38 7.0e-41 1.8e-39
12 IL gene expression LOC120098827 0.21 0.12 6.6e-03 0.06 0.02 -0.01 0.03 1.6e-02 1.1e-01 7.2e-01 8.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.11.94.0-1.51.5-1.61.6-1.4-1.5-1.2-1.0-0.90.91.32.0
Area under the delay curve0.60.62.7-0.10.2-0.10.10.1-0.1-0.01.01.6-1.6-0.7-0.6
BMI with tail0.62.18.7-0.20.2-0.10.2-0.50.6-0.52.92.5-2.50.71.5
BMI without tail0.91.96.40.9-1.01.0-0.90.40.7-0.12.52.5-2.5-0.00.3
Body weight2.18.824.62.4-2.52.6-2.51.53.21.05.04.6-4.6-0.2-0.1
Weight adjusted by age1.82.04.01.5-1.31.4-1.30.91.61.02.01.7-1.7-0.7-1.2
Bone surface0.20.40.80.7-0.90.7-0.70.70.80.60.00.1-0.1-0.7-0.2
Bone volume0.10.10.5-0.30.2-0.30.3-0.3-0.2-0.40.30.4-0.40.20.7
Breakpoint value in progressive ratio session0.30.41.2-0.20.3-0.30.30.0-0.30.3-1.1-1.11.1-0.6-0.3
Number of licking bursts1.21.43.21.0-1.11.0-1.01.30.91.5-1.2-0.90.9-1.3-1.8
Context. condit. distance diff. score4.14.911.91.6-1.61.5-1.51.91.42.2-3.2-3.43.4-1.6-1.4
Locomotion velocity, session 10.40.40.70.6-0.60.6-0.60.70.30.6-0.9-0.70.7-0.4-0.6
Locomotion distance, session 10.71.01.8-1.21.3-1.31.3-0.9-1.2-0.9-0.40.1-0.10.91.0
Locomotion velocity, session 20.30.30.70.6-0.60.5-0.60.80.40.6-0.7-0.20.2-0.8-0.7
Locomotion distance, session 20.10.20.7-0.40.5-0.50.5-0.0-0.20.1-0.8-0.40.40.00.5
Locomotion velocity, session 30.70.82.0-0.90.8-0.90.8-1.0-1.0-1.10.60.6-0.61.40.6
Locomotion distance, session 30.60.61.7-0.60.6-0.70.7-0.4-0.8-0.4-1.3-1.11.10.60.7
Stereotopy head waving bouts, day 31.61.92.81.6-1.71.6-1.61.61.61.30.60.7-0.7-1.0-1.7
Stereotopy head waving duration, day 30.81.01.91.1-1.21.2-1.21.01.00.80.80.7-0.7-0.6-1.4
Locomotion velocity, session 71.21.35.1-0.30.4-0.50.4-0.1-0.40.1-2.3-2.12.10.30.9
Locomotion distance, session 71.51.95.8-1.01.2-1.21.2-0.6-1.3-0.4-2.4-2.02.00.31.2
Stereotopy head waving bouts, day 70.40.51.90.5-0.50.5-0.50.50.1-0.10.81.4-1.40.0-0.4
Stereotopy head waving duration, day 70.70.92.50.8-0.90.9-0.90.70.50.11.21.6-1.6-0.1-0.6
Locomotion velocity, session 85.26.29.42.9-2.82.8-2.83.12.62.9-1.6-1.41.4-2.5-2.4
Locomotion distance, session 82.23.28.11.2-1.11.0-1.01.71.32.0-2.9-2.72.7-1.4-0.8
Degree of sensitization distance0.80.81.70.8-0.70.7-0.70.90.81.1-0.9-0.90.9-1.3-0.9
Degree of sensitization stereotypy0.30.31.30.3-0.30.3-0.30.4-0.2-0.30.41.1-1.1-0.0-0.1
Conditioned locomotion0.60.71.70.9-0.90.9-0.90.91.31.00.70.5-0.5-0.6-0.9
Cocaine response after cond. corrected0.20.20.5-0.40.5-0.50.5-0.00.10.4-0.7-0.50.5-0.70.1
Cocaine response after cond. not corrected0.91.02.51.0-0.91.0-1.01.11.21.3-0.1-0.10.1-1.6-1.0
Cocaine response before conditioning2.73.25.42.2-2.32.3-2.31.81.81.11.61.4-1.4-1.2-1.7
Saline control response2.02.64.6-1.31.1-1.21.2-1.8-1.2-2.02.21.8-1.82.01.4
Bone: connectivity density0.81.33.4-0.70.7-0.80.8-0.7-0.6-0.3-1.6-1.81.80.61.5
Bone: cortical apparent density1.92.63.6-1.71.8-1.61.7-1.9-1.4-1.81.61.5-1.51.51.2
Bone: cortical area0.60.93.30.5-0.50.5-0.50.50.60.21.41.8-1.8-0.5-0.1
Bone: cortical porosity0.40.41.0-0.50.4-0.50.4-0.4-1.0-0.90.51.0-1.00.20.1
Bone: cortical porosity0.30.30.80.6-0.70.6-0.60.6-0.00.10.20.6-0.6-0.6-0.9
Bone: cortical thickness3.04.810.4-1.91.9-1.81.9-1.8-1.5-2.12.53.2-3.21.62.0
Bone: cortical thickness3.03.54.2-1.92.0-1.91.9-2.0-1.6-2.01.61.7-1.72.02.1
Bone: cortical tissue density1.62.13.1-1.51.6-1.41.5-1.8-1.2-1.61.51.3-1.31.31.0
Condit. Reinf. active minus inactive responses0.30.31.0-0.10.0-0.10.1-0.1-0.6-0.3-1.0-0.90.9-0.00.4
Condit. Reinf. active-inactive response ratio0.30.30.7-0.60.5-0.60.6-0.7-0.8-0.80.30.4-0.40.40.6
Condit. Reinf. active responses0.40.51.3-0.40.4-0.50.5-0.5-0.8-0.5-1.1-1.11.10.30.8
Condit. Reinf. inactive responses1.21.52.7-1.21.2-1.31.2-1.1-1.3-1.0-1.1-1.11.11.01.6
Incentive salience index mean1.21.53.80.9-1.00.8-0.91.10.61.1-2.0-1.71.7-1.2-0.4
Condit. Reinf. lever presses2.53.46.71.4-1.41.3-1.31.81.32.0-2.6-2.52.5-2.1-1.0
Condit. Reinf. active minus inactive responses0.40.51.00.7-0.70.8-0.80.50.60.31.01.0-1.0-0.4-0.6
Condit. Reinf. active-inactive response ratio1.31.41.81.2-1.31.3-1.31.21.20.91.11.2-1.2-1.0-1.2
Condit. Reinf. active responses0.00.00.00.2-0.20.2-0.2-0.1-0.1-0.20.2-0.10.10.10.0
Condit. Reinf. inactive responses0.60.81.5-0.60.6-0.70.6-1.0-0.9-0.8-0.6-1.21.20.91.1
Condit. Reinf. lever presses0.20.20.6-0.20.3-0.30.3-0.4-0.6-0.5-0.5-0.70.70.20.8
Condit. Reinf. lever reinforcers received0.00.00.10.3-0.20.2-0.30.0-0.1-0.1-0.1-0.30.3-0.0-0.0
Conditioned reinforcement - actives0.20.20.7-0.0-0.1-0.10.10.00.20.10.60.8-0.8-0.7-0.2
Conditioned reinforcement - inactives0.80.93.0-0.60.5-0.70.7-0.7-0.6-0.81.21.7-1.70.30.6
Conditioned locomotion0.10.10.30.3-0.50.3-0.30.30.50.40.10.1-0.1-0.6-0.4
Patch foraging indifference point 0 sec1.82.84.2-1.71.7-1.71.6-2.1-1.5-2.01.81.5-1.51.91.2
Patch foraging indifference point AUC0.60.72.10.7-0.80.7-0.90.80.40.30.81.4-1.4-0.3-0.5
Delay disc. indifference point, 0s delay0.80.92.80.9-0.70.8-0.71.00.91.1-0.00.5-0.5-1.7-1.2
Delay disc. indifference point, 16s delay2.02.13.4-1.61.6-1.71.6-1.3-1.4-1.31.21.9-1.90.50.6
Delay disc. indifference point, 2s delay1.11.22.40.9-0.91.0-0.91.10.90.90.81.3-1.3-1.5-1.5
Delay disc. indifference point, 24s delay0.40.40.7-0.60.5-0.60.5-0.6-0.6-0.60.80.9-0.9-0.2-0.2
Delay disc. indifference point, 4s delay1.31.31.81.3-1.21.2-1.21.01.00.71.01.4-1.4-1.1-1.0
Delay disc. indifference point, 8s delay0.10.10.5-0.10.2-0.10.20.1-0.1-0.00.20.7-0.7-0.3-0.3
Indifference point function ln k0.60.92.20.6-0.70.6-0.60.80.50.8-1.0-1.11.1-1.3-1.5
Indifference point function log k0.60.92.20.6-0.70.6-0.60.80.50.8-1.0-1.11.1-1.3-1.5
Patch foraging total patch changes 0 sec2.23.54.9-1.91.9-1.91.8-2.2-1.7-2.22.01.7-1.72.01.4
Patch foraging total patch changes 12 sec1.92.53.0-1.71.5-1.71.5-1.7-1.5-1.71.61.7-1.71.51.1
Patch foraging total patch changes 18 sec4.35.69.2-2.62.5-2.72.4-2.8-2.3-2.71.51.4-1.43.02.4
Patch foraging total patch changes 24 sec4.65.78.4-2.92.8-2.92.8-2.8-2.7-2.60.60.8-0.82.52.4
Patch foraging total patch changes 6 sec2.84.25.8-2.32.2-2.32.1-2.4-2.0-2.31.91.8-1.82.11.3
Patch foraging time to switch 0 sec1.11.72.9-1.61.7-1.51.7-1.7-0.9-1.10.60.1-0.11.31.5
Patch foraging water rate 0 sec0.10.20.8-0.1-0.0-0.1-0.10.20.20.20.70.9-0.9-0.2-0.6
Patch foraging water rate 12 sec0.40.71.1-1.00.9-1.11.1-0.9-1.1-1.00.00.2-0.20.70.6
Patch foraging water rate 18 sec0.10.10.30.5-0.50.4-0.30.20.3-0.00.50.5-0.50.10.0
Patch foraging water rate 24 sec0.30.51.80.0-0.30.0-0.20.20.2-0.21.11.3-1.3-0.10.7
Patch foraging water rate 6 sec0.30.40.9-0.80.7-0.80.9-0.6-0.7-0.60.30.4-0.40.70.3
Seeking ratio, delayed vs. immediate footshock0.20.20.60.4-0.40.3-0.40.1-0.1-0.30.60.8-0.8-0.20.1
Distance traveled before self-admin0.70.81.61.0-1.01.0-1.00.91.21.1-0.2-0.60.6-0.6-0.5
Distance traveled after self-admin0.50.61.21.1-1.11.0-1.00.60.90.60.5-0.10.1-0.2-0.6
Extensor digitorum longus weight0.41.52.51.3-1.41.4-1.41.31.51.5-0.2-0.40.4-1.6-1.3
Bone: elastic displacement0.70.81.4-0.90.9-0.90.9-0.9-1.1-1.20.40.7-0.71.00.9
Bone: elastic work0.50.73.1-0.20.1-0.20.2-0.1-0.1-0.41.31.8-1.80.20.4
Bone: endosteal estimation5.211.319.34.1-4.44.2-4.33.64.03.40.80.2-0.2-3.1-3.5
Bone: endosteal perimeter4.69.514.33.6-3.83.6-3.63.53.53.4-1.0-1.51.5-3.2-3.0
Epididymis fat weight8.920.827.7-5.35.1-5.25.1-5.2-4.0-4.84.13.9-3.94.13.8
Delta time in closed arm before/after self-admin0.20.20.80.1-0.00.1-0.10.10.60.60.70.3-0.3-0.5-0.9
Delta time in open arm before/after self-admin0.30.31.0-0.20.2-0.20.2-0.5-0.5-0.80.20.3-0.30.81.0
Diff in mean of infusions in LGA sessions1.31.43.6-1.01.3-1.31.3-0.6-1.1-0.2-1.9-1.61.6-0.10.5
Delay discount exponential model param0.50.62.50.1-0.20.2-0.2-0.10.20.1-1.0-1.61.60.60.6
Extinction: sum of active levers before priming0.30.30.6-0.50.8-0.70.7-0.3-0.50.1-0.6-0.30.3-0.8-0.6
Active lever presses in extinction session 60.50.50.9-0.90.9-0.91.0-0.9-0.7-0.70.40.1-0.10.70.6
Bone: final force1.93.112.7-0.40.2-0.30.3-0.40.4-0.63.23.6-3.60.50.7
Bone: final moment1.72.811.3-0.20.0-0.10.2-0.30.4-0.63.03.4-3.40.50.8
Food consumed during 24 hour testing period1.21.53.21.5-1.51.5-1.51.41.81.40.40.2-0.2-0.6-0.8
Glucose7.010.617.03.5-3.23.4-3.53.73.33.9-2.3-2.42.4-4.1-2.7
Heart weight0.10.10.50.4-0.40.4-0.40.30.20.30.40.2-0.2-0.7-0.4
Delay discount hyperbolic model param0.50.62.3-0.20.1-0.10.1-0.3-0.0-0.1-0.9-1.51.50.80.7
Intermittent access intake day 1-15 change0.40.41.40.0-0.20.2-0.2-0.1-0.3-0.80.50.7-0.71.21.1
Intermittent access intake escalation0.40.40.90.8-0.80.9-1.00.60.4-0.0-0.10.0-0.00.60.6
Intermittent access intake escalation 22.82.85.32.3-2.12.3-2.32.11.61.5-1.2-1.01.0-0.8-0.7
Intermitt. access day 1 inactive lever presses1.21.32.61.1-1.11.1-1.11.21.41.50.0-0.10.1-1.5-1.6
Intermitt. access day 15 inactive lever presses0.60.72.50.2-0.40.3-0.30.10.4-0.11.51.6-1.60.1-0.3
Intermitt. access escalation Index0.90.83.0-0.20.4-0.30.3-0.0-0.40.3-1.7-1.71.7-0.4-0.3
Intermittent access day 1 total infusions0.20.30.6-0.70.5-0.80.8-0.5-0.7-0.4-0.6-0.10.1-0.10.4
Intermittent access day 15 total infusions0.20.20.6-0.50.3-0.40.4-0.4-0.6-0.6-0.20.1-0.10.50.8
Intermittent access terminal intake (last 3 days)0.10.10.3-0.30.1-0.30.3-0.3-0.3-0.30.20.5-0.50.00.3
Intermittent access total infusions0.20.20.3-0.50.4-0.50.5-0.5-0.5-0.50.10.3-0.30.20.5
Intermittent access day 1 locomotion0.10.10.20.4-0.50.4-0.40.20.40.3-0.3-0.30.3-0.30.0
Intermittent access day 15 total locomotion0.90.92.41.3-1.51.3-1.30.91.20.50.60.6-0.60.20.1
Intermittent access total locomotion0.60.71.61.1-1.31.1-1.20.61.00.30.40.5-0.50.30.6
Intermittent access standard deviation1.01.13.9-0.60.5-0.40.4-0.7-0.2-0.92.01.7-1.70.80.6
Left kidney weight1.13.010.41.1-1.11.2-1.20.61.50.23.23.0-3.00.2-0.1
Right kidney weight1.33.66.82.1-2.12.1-2.11.42.20.92.62.2-2.2-0.4-0.4
Cocaine induced anxiety1.61.95.11.1-1.21.1-1.21.00.91.1-1.9-2.32.3-0.4-0.1
Post-drug Anxiety0.80.92.30.7-0.80.8-0.80.70.91.0-0.9-1.51.5-0.6-0.7
Baseline Anxiety0.70.71.4-1.21.2-1.11.2-0.9-0.8-0.40.70.4-0.4-0.4-0.8
Tail length4.012.321.74.5-4.74.6-4.63.93.82.81.72.0-2.0-2.4-3.0
Length with tail2.710.115.93.8-4.03.9-4.03.23.82.42.52.7-2.7-1.7-2.3
Length without tail1.53.46.71.8-1.91.8-2.01.62.61.52.12.1-2.1-0.9-1.0
Times rat made contact with spout2.73.26.0-2.02.0-2.02.0-2.0-2.4-2.2-0.4-0.30.31.91.9
Lifetime Intake0.10.10.2-0.40.1-0.40.4-0.3-0.3-0.20.10.3-0.3-0.20.1
Liver weight, left1.11.83.71.8-1.91.9-1.91.31.81.10.50.1-0.1-0.5-0.8
Liver weight, right4.37.111.83.4-3.43.4-3.43.33.12.60.40.8-0.8-2.1-2.4
Locomotor activity2.43.88.83.0-2.82.9-2.72.22.11.50.3-0.00.0-0.6-1.3
Locomotor testing distance0.50.81.71.3-1.21.3-1.10.81.00.70.2-0.10.1-0.3-0.7
Locomotor testing rearing0.91.43.01.7-1.71.6-1.61.11.61.00.60.2-0.2-0.2-0.7
Locomotion in novel chamber0.20.31.30.4-0.40.4-0.40.30.30.00.61.1-1.10.2-0.1
Locomotion in novel chamber post-restriction0.30.31.5-0.30.3-0.20.3-0.40.1-0.31.21.0-1.00.10.2
Fecal boli incidents, locomotor time 10.20.20.7-0.20.3-0.30.3-0.5-0.3-0.2-0.4-0.90.90.20.5
Change in fecal boli incidents, locomotor task1.01.03.40.5-0.40.6-0.41.00.81.30.20.5-0.5-1.8-1.8
Time >=10cm from walls, locomotor time 11.81.84.11.5-1.61.5-1.61.32.01.70.5-0.20.2-1.0-1.4
Bouts of movement, locomotor time 10.70.72.20.8-0.70.7-0.60.70.30.5-1.5-1.41.4-0.10.0
Total resting periods, locomotor time 10.70.71.51.0-0.90.9-0.90.90.60.7-1.2-1.01.0-0.3-0.2
Rest time, locomotor task time 11.21.33.51.6-1.91.6-1.51.21.10.9-0.4-0.70.7-0.1-0.5
Distance moved, locomotor task time 10.50.61.4-0.70.9-0.70.5-0.6-0.4-0.51.01.2-1.20.20.3
Vertical activity count, locomotor time 10.50.50.8-0.80.8-0.70.5-0.7-0.4-0.60.90.9-0.90.50.7
Time >=10cm from walls, locomotor time 20.91.01.90.9-0.81.0-0.90.81.31.30.3-0.70.7-1.2-1.4
Bouts of movement, locomotor time 21.51.63.82.0-1.92.0-1.91.51.10.7-0.2-0.40.4-0.3-0.3
Total resting periods, locomotor time 22.32.45.32.3-2.32.3-2.21.81.41.1-0.5-0.70.7-0.7-0.8
Rest time, locomotor task time 24.34.98.92.7-3.02.7-2.62.52.52.4-1.3-1.71.7-1.2-1.5
Distance moved, locomotor task time 21.72.03.2-1.71.8-1.61.4-1.5-1.0-1.21.41.6-1.60.80.9
Vertical activity count, locomotor time 20.80.91.6-1.21.3-1.21.1-1.2-0.7-0.80.90.7-0.70.50.6
Light reinforcement 10.40.71.4-1.11.0-1.01.2-0.9-0.4-0.60.80.6-0.60.70.8
Light reinforcement 20.40.51.60.9-0.80.9-0.80.71.30.70.70.5-0.50.1-0.1
Bone: marrow area5.111.018.94.1-4.34.1-4.23.54.03.30.90.2-0.2-3.1-3.4
Bone: maximum diameter2.64.77.12.6-2.62.6-2.62.72.52.5-0.5-0.30.3-2.4-2.1
Bone: maximum force1.42.510.40.0-0.30.1-0.1-0.00.6-0.42.83.2-3.20.50.5
Bone: maximum moment1.32.29.00.2-0.50.3-0.30.10.7-0.32.73.0-3.00.40.4
Mean time between licks in bursts3.65.17.62.6-2.82.6-2.62.72.22.5-1.5-1.41.4-2.3-2.0
Mean num. licks in bursts3.03.66.7-1.92.0-1.91.9-2.3-2.1-2.50.90.7-0.72.22.6
Cd content in liver1.11.22.5-1.00.9-1.00.9-1.0-0.4-0.91.11.1-1.11.61.5
Co content in liver1.61.94.0-1.31.2-1.11.2-1.4-0.7-1.12.01.9-1.91.30.4
Cu content in liver3.54.36.6-2.42.4-2.52.4-2.2-2.6-2.0-1.1-1.01.02.02.2
Fe content in liver1.01.22.3-1.00.9-1.00.9-1.2-0.8-1.31.21.0-1.01.51.2
K content in liver0.20.20.8-0.10.1-0.20.10.40.00.5-0.8-0.30.3-0.9-0.6
Mg content in liver3.13.25.81.3-1.21.2-1.21.81.02.0-2.4-2.02.0-2.4-2.2
Mn content in liver6.67.511.02.8-2.82.6-2.82.92.63.1-2.0-2.22.2-3.3-3.0
Na content in liver0.10.20.3-0.50.5-0.50.5-0.0-0.4-0.1-0.20.5-0.5-0.2-0.2
Rb content in liver0.30.31.1-0.40.4-0.50.4-0.10.10.4-0.8-1.01.0-0.2-0.3
Se content in liver4.45.47.82.5-2.42.4-2.42.61.62.3-2.3-1.91.9-2.8-2.4
Sr content in liver1.21.11.91.2-1.21.1-1.21.01.41.10.40.4-0.4-1.3-0.9
Zn content in liver0.30.31.10.3-0.30.3-0.30.50.70.8-0.1-0.20.2-1.1-0.9
Bone: minimum diameter3.15.89.22.9-3.02.9-2.92.72.92.6-0.1-0.30.3-2.7-2.3
Time in familiar zone, hab. session 14.44.17.2-2.22.3-2.22.2-2.3-2.6-2.4-0.7-0.70.71.82.7
Time in novel zone, hab. session 12.92.95.91.9-2.01.9-1.91.82.21.90.60.3-0.3-1.2-2.4
Total zone transitions, hab. session 10.20.20.8-0.40.5-0.50.5-0.2-0.5-0.0-0.9-0.70.7-0.20.2
Total locomotion distance, hab. session 10.20.30.6-0.60.7-0.70.7-0.3-0.5-0.1-0.8-0.60.6-0.20.5
Locomotion velocity, hab. session 10.20.30.7-0.80.8-0.80.8-0.5-0.7-0.2-0.4-0.20.2-0.30.5
Time in familiar zone, hab. session 20.70.71.6-0.80.9-0.80.8-1.0-1.0-1.1-0.0-0.10.10.81.2
Time in novel zone, hab. session 20.20.20.30.3-0.50.3-0.40.30.40.20.50.4-0.40.4-0.6
Total zone transitions, hab. session 20.10.20.4-0.60.6-0.60.6-0.3-0.3-0.10.00.4-0.40.10.4
Total locomotion distance, hab. session 20.40.61.0-0.80.9-0.90.9-0.5-0.5-0.1-1.0-0.80.80.20.7
Locomotion velocity, hab. session 20.40.51.5-0.80.8-0.80.9-0.3-0.50.1-1.2-0.90.9-0.20.6
Novel to familiar place preference ratio0.20.20.4-0.50.5-0.60.6-0.3-0.6-0.3-0.10.3-0.30.4-0.4
Novelty place preference0.10.10.3-0.30.2-0.30.3-0.1-0.4-0.20.00.4-0.40.3-0.5
Time in novel zone, NPP test0.10.10.4-0.10.0-0.10.20.0-0.3-0.20.10.5-0.50.3-0.6
Total zone transitions, NPP test0.30.41.5-0.40.5-0.50.5-0.2-0.30.1-1.2-1.11.10.10.5
Total locomotion distance, NPP test0.60.81.3-1.11.1-1.11.1-0.7-0.6-0.2-0.9-0.90.90.40.9
Locomotion velocity, NPP test0.81.21.9-1.31.4-1.31.4-0.8-0.8-0.3-1.3-1.21.20.40.9
Intraocular pressure0.71.05.6-0.40.4-0.50.4-0.7-0.6-0.8-0.6-1.11.11.22.4
Delta distance traveled before/after self-admin0.30.41.20.2-0.20.2-0.2-0.1-0.2-0.61.11.1-1.10.6-0.1
Delta ambulatory time before/after self-admin0.20.20.40.6-0.70.7-0.60.40.20.00.50.4-0.40.1-0.4
Parametrial fat weight0.81.64.90.0-0.10.10.0-0.30.4-0.62.22.2-2.21.21.6
Pavlov. Cond. lever latency3.74.77.9-2.22.1-2.12.1-2.6-1.7-2.42.51.8-1.82.81.6
Pavlov. Cond. magazine entry latency2.83.64.82.1-2.02.0-2.02.11.21.7-2.2-2.02.0-1.9-1.4
Pavlov. Cond. change in total contacts2.32.54.41.9-2.01.8-1.92.01.31.5-0.8-0.20.2-2.1-1.4
Pavlov. Cond. index score4.35.58.02.4-2.42.3-2.42.71.72.4-2.6-2.12.1-2.8-1.8
Pavlov. Cond. latency score4.35.58.62.5-2.42.4-2.42.91.82.5-2.5-1.91.9-2.9-1.8
Pavlov. Cond. lever contacts4.04.78.92.3-2.22.2-2.22.72.02.5-2.0-1.41.4-3.0-1.7
Pavlov. Cond. magazine entry number1.92.44.3-1.41.4-1.41.4-1.4-0.7-1.22.02.1-2.11.70.9
Pavlov. Cond. intertrial magazine entries2.42.94.9-2.01.9-2.02.0-2.2-1.6-1.80.70.3-0.32.21.7
Pavlov. Cond. lever-magazine prob. diff.4.25.27.72.3-2.32.2-2.22.61.62.3-2.6-2.22.2-2.8-1.7
Pavlov. Cond. response bias3.44.25.72.1-2.12.0-2.02.21.41.9-2.3-2.22.2-2.4-1.4
Pavlov. Cond. lever latency0.30.41.20.4-0.60.5-0.50.70.80.80.30.4-0.4-0.7-1.1
Pavlov. Cond. magazine entry latency0.30.40.70.8-0.80.7-0.70.90.60.60.10.5-0.5-0.70.1
Pavlov. Cond. change in total contacts0.30.41.1-0.40.5-0.50.4-0.6-0.8-0.90.50.7-0.70.61.0
Pavlov. Cond. index score0.10.10.60.00.00.0-0.0-0.1-0.3-0.3-0.00.1-0.10.10.8
Pavlov. Cond. latency score0.10.10.6-0.00.1-0.10.0-0.1-0.3-0.40.20.3-0.30.10.8
Pavlov. Cond. lever contacts0.91.33.3-1.01.1-1.01.0-1.3-1.3-1.40.20.1-0.11.51.8
Pavlov. Cond. magazine entry number0.10.10.4-0.20.2-0.20.2-0.2-0.20.0-0.3-0.60.6-0.1-0.6
Pavlov. Cond. intertrial magazine entries1.62.03.71.3-1.31.3-1.31.30.81.3-1.8-1.91.9-1.2-1.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.70.00.00.0-0.0-0.1-0.3-0.30.00.1-0.10.20.9
Pavlov. Cond. response bias0.30.41.9-0.30.4-0.40.3-0.5-0.8-0.8-0.3-0.10.10.91.4
Time in closed arm before self-admin0.00.00.1-0.20.1-0.20.2-0.1-0.1-0.00.00.1-0.1-0.2-0.3
Time in closed arm after self-admin0.50.51.3-0.70.7-0.60.7-0.5-0.3-0.41.01.1-1.10.2-0.2
Time in open arm before self-admin0.60.71.21.0-1.01.0-1.00.90.30.4-1.0-1.11.1-0.0-0.2
Time in open arm after self-admin0.40.41.20.7-0.60.6-0.60.2-0.2-0.1-1.0-1.11.10.30.3
Bone: periosteal estimation2.65.38.62.7-2.92.8-2.82.42.82.11.51.2-1.2-2.1-2.1
Bone: periosteal perimeter2.23.75.92.3-2.42.3-2.32.32.32.00.20.3-0.3-2.1-1.8
Bone: post-yield work1.62.24.01.8-2.01.8-1.81.61.81.6-0.4-0.90.9-1.0-1.3
Progressive ratio test 1 active lever presses0.10.10.2-0.30.2-0.30.3-0.2-0.30.0-0.30.1-0.1-0.4-0.2
Progressive ratio test 1 breakpoint0.10.10.3-0.40.2-0.50.5-0.3-0.30.1-0.20.3-0.3-0.5-0.3
Progressive ratio test 1 inactive lever presses0.70.81.6-1.21.1-1.21.3-1.0-0.9-0.80.40.6-0.60.50.5
Progressive ratio test 2 active lever presses0.40.40.8-0.70.6-0.80.8-0.7-0.9-0.7-0.6-0.40.40.50.8
Progressive ratio test 2 breakpoint0.70.81.4-0.90.8-1.01.0-0.9-1.2-0.9-0.8-0.60.60.71.1
Progressive ratio test 2 inactive lever presses0.20.20.60.5-0.60.4-0.40.50.30.20.20.8-0.8-0.1-0.2
Incentive Sensitization - Responses0.40.50.9-0.50.4-0.60.6-0.5-0.9-0.7-0.9-0.70.70.61.0
Incentive Sensitization - Breakpoint0.50.51.2-0.50.4-0.50.5-0.4-0.8-0.7-0.9-0.80.80.71.1
Sum of active levers in priming session hrs 5-60.20.20.3-0.40.5-0.40.5-0.2-0.30.1-0.4-0.60.6-0.2-0.5
Progressive ratio1.51.86.90.2-0.20.3-0.2-0.40.3-0.82.62.4-2.41.10.7
Food seeking constrained by brief footshock0.10.10.2-0.30.0-0.20.0-0.3-0.2-0.30.0-0.20.20.40.5
Seeking ratio, punishment vs. effort1.31.65.7-0.30.3-0.40.30.2-0.50.6-2.4-2.42.4-1.0-0.7
Retroperitoneal fat weight0.10.42.10.00.10.10.1-0.30.2-0.31.41.1-1.10.50.3
Reaction time number correct1.42.03.2-1.71.5-1.61.7-1.8-1.2-1.51.30.8-0.81.41.2
Reaction time mean minus median4.56.011.63.4-3.13.3-3.12.92.42.2-1.8-1.71.7-1.1-0.7
Reaction time mean minus median AUC3.14.07.02.6-2.52.6-2.42.42.01.9-1.8-1.61.6-1.0-0.1
Reaction time num false alarms0.30.40.90.6-0.60.6-0.60.90.50.7-0.00.5-0.5-0.9-1.0
Reaction time num false alarms AUC0.50.61.70.7-0.70.7-0.71.00.50.70.10.7-0.7-1.1-1.3
Reaction time trials correct on left1.42.03.2-1.71.5-1.61.7-1.8-1.2-1.51.30.8-0.81.41.2
Reaction time trials on left1.31.82.9-1.61.4-1.51.6-1.7-1.1-1.41.30.8-0.81.31.1
Reaction time mean4.15.78.72.9-2.72.9-2.72.82.62.7-1.9-1.91.9-1.8-1.1
Reaction time mean AUC4.25.68.73.0-2.82.9-2.72.82.62.6-1.9-1.91.9-1.6-0.9
Median of all reaction times2.73.75.42.2-2.12.1-2.02.22.22.3-1.5-1.61.6-1.7-1.1
Reaction time omissions2.83.96.32.5-2.42.5-2.42.32.02.0-1.6-1.61.6-1.2-0.1
Reaction time false alarm rate1.42.03.71.6-1.41.5-1.61.91.21.6-0.70.1-0.1-1.9-1.8
Reaction time premature initiation rate0.50.62.0-0.0-0.00.10.10.10.60.21.41.4-1.4-0.4-0.9
Reaction time premature initiations0.91.34.6-0.90.7-0.81.0-0.8-0.1-0.62.11.9-1.90.3-0.2
Std. dev. reaction times4.86.812.63.5-3.23.5-3.23.22.62.6-1.8-1.61.6-1.7-1.1
Reaction time trials completed1.31.82.9-1.61.4-1.51.6-1.7-1.1-1.41.30.8-0.81.31.1
Reaction time trials AUC1.21.82.9-1.61.4-1.61.6-1.7-1.1-1.41.30.7-0.71.41.1
Run reversals in cocaine runway, females1.31.31.8-1.21.3-1.31.3-1.3-1.1-1.30.80.8-0.81.21.2
Run reversals in cocaine runway, males3.23.16.72.6-2.42.4-2.42.21.91.6-0.5-0.40.4-1.1-0.8
Latency to leave start box in cocaine runway0.30.31.30.10.10.00.10.60.30.8-0.30.1-0.1-1.1-0.9
Latency to leave start box in cocaine runway, F0.30.31.00.3-0.10.1-0.10.60.30.8-0.9-0.60.6-1.0-0.5
Latency to leave start box in cocaine runway, M0.40.41.7-0.40.4-0.40.5-0.1-0.1-0.10.91.3-1.3-0.1-0.2
Std. dev. time between licks in bursts4.65.58.22.5-2.92.5-2.52.72.42.8-1.1-1.01.0-2.6-2.8
Total sessions with >9 infusions0.10.10.60.00.0-0.10.10.00.10.20.20.6-0.6-0.8-0.2
Short access day 1 total inactive lever presses2.32.63.91.7-1.91.8-1.81.91.82.0-0.6-0.30.3-1.9-1.7
Short access day 10 total inactive lever presses0.50.61.00.9-0.80.9-0.91.00.90.9-0.5-0.60.6-0.6-0.7
Short access day 1 total infusions0.20.21.5-0.1-0.2-0.10.20.1-0.00.4-0.6-0.30.3-1.2-0.7
Short access day 10 total infusions0.10.10.4-0.2-0.1-0.20.20.0-0.00.10.20.7-0.7-0.6-0.3
Short access total infusions0.20.21.0-0.1-0.2-0.20.20.1-0.00.20.20.6-0.6-1.0-0.6
Short access day 1 locomotion0.80.93.2-0.30.2-0.30.30.0-0.30.5-1.8-1.71.7-1.0-0.5
Short access day 10 total locomotion2.02.24.41.5-1.51.7-1.61.51.61.7-0.1-0.40.4-2.0-2.1
Short access total locomotion0.50.52.00.4-0.50.5-0.50.50.70.9-0.2-0.30.3-1.4-1.2
One hour access (0.3 mA shock)0.20.31.60.0-0.0-0.20.20.3-0.20.2-1.3-0.70.7-0.50.2
Compulsive drug intake1.41.44.10.10.2-0.00.00.5-0.01.0-2.0-2.02.0-1.4-1.2
One hour access (shock baseline)0.30.40.70.7-0.80.6-0.60.20.4-0.20.60.6-0.60.70.9
Social response proportion0.80.92.11.0-0.91.0-0.90.81.11.10.2-0.10.1-1.5-1.5
Social responses0.30.31.60.3-0.30.3-0.40.30.40.50.50.3-0.3-1.0-1.3
Social time4.25.58.52.7-2.72.8-2.72.92.52.7-1.3-0.90.9-2.6-2.1
Soleus weight4.513.220.24.0-3.94.0-4.04.24.14.4-1.0-1.11.1-4.3-4.5
Bone: stiffness0.61.02.9-0.60.4-0.50.5-0.6-0.2-0.71.61.7-1.70.71.0
Tibialis anterior weight0.51.83.3-1.81.6-1.71.7-1.5-1.4-1.40.70.7-0.71.01.2
Time to tail flick, vehicle, before self-admin0.30.30.70.7-0.60.6-0.60.70.50.5-0.8-0.50.5-0.20.4
Time to tail flick, vehicle, after self-admin1.51.62.31.5-1.31.2-1.31.31.11.3-1.3-1.51.5-0.7-0.8
Time to tail flick, test, before self-admin0.20.20.5-0.60.4-0.50.4-0.4-0.6-0.60.00.3-0.30.70.5
Time to tail flick, test, after self-admin1.11.12.71.0-0.90.9-0.90.70.10.1-1.6-1.71.70.70.9
Delta time to tail flick, vehicle, before/after SA0.20.20.90.10.0-0.00.0-0.0-0.2-0.0-0.7-1.01.00.2-0.1
Delta time to tail flick, test, before/after SA0.40.41.10.10.1-0.10.1-0.2-0.1-0.2-0.8-1.11.10.70.9
Tibia length2.67.512.33.3-3.43.3-3.32.73.52.61.71.2-1.2-2.4-2.7
Ambulatory time before self-admin0.10.10.30.5-0.40.4-0.40.40.50.4-0.1-0.00.00.10.2
Ambulatory time after self-admin0.40.51.21.1-1.01.0-1.00.60.70.40.2-0.20.20.0-0.5
Bone: tissue strength1.21.15.0-0.1-0.0-0.10.10.10.4-0.21.82.2-2.20.40.5
Total heroin consumption0.00.00.00.1-0.10.1-0.10.00.00.0-0.1-0.20.20.10.1
Bone: trabecular number1.62.56.0-1.71.7-1.81.7-1.5-1.7-1.4-1.1-0.70.71.72.5
Bone: trabecular spacing1.92.54.01.6-1.51.7-1.61.41.71.21.71.6-1.6-1.3-2.0
Bone: trabecular thickness1.01.23.3-1.11.0-1.21.2-1.1-1.1-1.0-0.7-0.70.71.01.8
Bone: trabecular tissue density0.50.72.80.2-0.30.3-0.20.3-0.0-0.21.11.7-1.7-0.4-0.8
Water consumed over 24 hours0.30.30.90.5-0.50.5-0.50.70.60.8-0.3-0.20.2-0.8-0.9
Number of responses in last shaping day0.90.94.00.5-0.60.5-0.50.90.61.10.00.5-0.5-1.8-2.0