LOC120098827

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	LOC120098827	0.37	0.1	4.3e-13	0.24	0.22	0.22	0.23	3.4e-13	9.7e-12	1.1e-11	2.3e-12
2	IC	gene expression	LOC120098827	0.23	0.1	3.7e-05	0.14	0.12	0.07	0.09	2.2e-06	1.2e-05	8.8e-04	2.0e-04
3	NAcc	gene expression	LOC120098827	0.24	0.07	0.0e+00	0.22	0.23	0.22	0.24	4.7e-32	1.1e-34	5.2e-33	1.4e-35
4	PL	gene expression	LOC120098827	0.39	0.12	0.0e+00	0.26	0.27	0.26	0.27	3.4e-28	6.3e-30	3.4e-28	2.5e-29
5	Brain	gene expression	LOC120098827	0.1	0.05	1.0e-05	0.04	0.04	0.04	0.04	2.4e-04	5.5e-05	1.9e-04	1.9e-04
6	Adipose	gene expression	LOC120098827	0.34	0.1	0.0e+00	0.28	0.32	0.3	0.31	4.6e-31	1.4e-35	7.8e-34	1.3e-34
7	pVTA	gene expression	LOC120098827	0.22	0.08	2.7e-14	0.16	0.16	0.17	0.18	1.0e-12	1.8e-12	1.5e-13	1.4e-14
8	RMTg	gene expression	LOC120098827	0.26	0.11	5.2e-05	0.18	0.15	0.1	0.13	1.5e-05	8.1e-05	1.3e-03	3.0e-04
9	IL	gene expression	LOC120098827	0.31	0.15	2.0e-03	0.12	0.04	0.07	0.11	8.2e-04	4.9e-02	9.9e-03	1.2e-03
10	Liver	gene expression	LOC120098827	0.06	0.04	6.1e-04	0.02	0.02	0.02	0.02	1.1e-03	4.4e-03	3.9e-03	3.3e-03
11	Adipose	isoform ratio	XR_005497411.2	0.03	0.03	5.6e-03	0.01	0	0.01	0.01	1.1e-02	7.3e-02	1.7e-02	2.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	1.2	2.1	3.5	1.5	1.4	-1.5	-1.4	-1.3	-1.6	-1.0	1.9	1.6	1.8	-0.5
Area under the delay curve	0.1	0.1	0.7	-0.0	-0.1	0.1	-0.0	0.3	0.3	-0.0	-0.5	-0.8	-0.5	-0.4
BMI with tail	0.5	1.6	2.6	1.5	1.3	-1.5	-1.0	-1.6	-1.6	-0.9	1.4	1.3	1.1	-0.3
BMI without tail	0.2	1.0	2.6	0.6	0.5	-0.5	-0.3	-1.2	-0.9	-1.2	1.1	0.9	1.1	-1.6
Body weight	0.7	3.1	8.7	-2.5	-2.5	2.2	3.0	1.6	1.6	1.5	-0.2	-0.7	0.2	0.2
Weight adjusted by age	0.5	1.4	2.4	-1.4	-1.4	1.4	1.5	1.0	1.3	1.1	-0.6	-1.1	-1.4	0.5
Bone surface	0.3	0.5	0.8	-0.9	-0.9	0.9	0.9	0.8	0.7	0.6	-0.4	-0.6	-0.2	0.6
Bone volume	0.1	0.1	0.8	0.1	0.1	-0.2	-0.0	-0.2	-0.4	-0.2	0.9	0.4	0.5	-0.2
Breakpoint value in progressive ratio session	0.0	0.1	0.2	-0.1	-0.4	0.1	0.2	0.1	0.2	-0.1	-0.2	-0.4	-0.2	-0.2
Number of licking bursts	0.7	2.2	5.4	-1.1	-1.1	1.2	0.8	1.4	1.5	1.3	-2.3	-1.8	-1.8	1.3
Context. condit. distance diff. score	2.8	3.4	7.5	-1.6	-1.6	1.7	1.6	1.9	1.7	2.3	-1.3	-1.9	-1.6	2.7
Locomotion velocity, session 1	0.3	0.3	0.6	-0.7	-0.7	0.6	0.5	0.8	0.7	0.4	-0.5	-0.5	0.0	0.1
Locomotion distance, session 1	0.8	1.0	1.8	1.3	1.4	-1.3	-1.3	-0.9	-1.1	-0.6	0.8	1.0	0.8	0.2
Locomotion velocity, session 2	0.2	0.3	0.7	-0.5	-0.5	0.4	0.4	0.8	0.6	0.4	-0.3	-0.5	-0.8	0.3
Locomotion distance, session 2	0.2	0.3	1.4	0.5	0.5	-0.5	-0.4	-0.1	-0.3	0.4	0.4	0.5	0.9	1.2
Locomotion velocity, session 3	0.8	0.9	1.9	0.9	1.0	-0.9	-1.0	-1.0	-0.9	-1.1	1.0	0.8	0.3	-1.4
Locomotion distance, session 3	0.4	0.5	1.5	0.6	0.8	-0.6	-0.7	-0.4	-0.6	-0.3	1.2	0.7	0.6	-0.1
Stereotopy head waving bouts, day 3	1.9	2.3	2.9	-1.7	-1.7	1.6	1.7	1.6	1.7	1.2	-1.6	-1.7	-1.3	0.4
Stereotopy head waving duration, day 3	0.9	1.1	1.8	-1.2	-1.2	1.1	1.1	1.0	1.2	0.5	-1.4	-1.3	-0.9	-0.6
Locomotion velocity, session 7	0.4	0.4	1.2	0.5	0.5	-0.4	-0.4	-0.1	-0.5	0.5	0.8	0.7	0.8	1.1
Locomotion distance, session 7	0.7	0.9	1.4	1.1	1.2	-1.0	-1.2	-0.5	-0.9	-0.2	1.2	1.1	1.1	0.4
Stereotopy head waving bouts, day 7	0.5	0.5	1.6	-0.8	-0.8	0.7	0.6	0.8	0.8	-0.3	-0.7	-0.5	-0.3	-1.2
Stereotopy head waving duration, day 7	0.4	0.5	1.2	-0.8	-0.8	0.8	0.7	0.7	0.7	-0.1	-0.7	-0.5	-0.2	-1.1
Locomotion velocity, session 8	6.6	8.0	10.0	-2.8	-2.8	3.0	2.7	3.2	3.1	2.8	-2.9	-2.9	-2.4	2.3
Locomotion distance, session 8	1.8	2.6	10.9	-1.1	-1.1	1.2	1.2	1.7	1.3	2.4	-0.8	-1.2	-0.5	3.3
Degree of sensitization distance	1.0	1.1	2.3	-0.8	-0.8	0.9	0.8	1.0	1.0	1.1	-1.5	-1.2	-0.9	1.2
Degree of sensitization stereotypy	0.2	0.2	1.0	-0.2	-0.2	0.2	0.0	0.3	0.2	-0.6	-0.3	-0.1	-0.0	-1.0
Conditioned locomotion	0.7	0.8	1.1	-0.9	-0.9	0.8	1.0	0.8	0.8	1.1	-0.8	-0.9	-0.8	1.0
Cocaine response after cond. corrected	0.2	0.4	2.6	0.5	0.5	-0.4	-0.3	-0.0	-0.2	0.8	0.1	-0.2	-0.0	1.6
Cocaine response after cond. not corrected	0.8	1.2	2.0	-0.9	-0.9	1.0	1.0	1.1	1.1	1.3	-0.9	-1.3	-1.0	1.4
Cocaine response before conditioning	2.5	3.0	5.1	-2.3	-2.3	2.2	2.2	1.7	2.0	0.7	-1.4	-1.6	-1.3	-0.8
Saline control response	2.2	3.0	9.6	1.1	1.1	-1.2	-1.1	-1.8	-1.6	-2.0	2.1	1.6	1.5	-3.1
Bone: connectivity density	0.4	0.6	2.1	0.7	0.7	-0.8	-0.6	-0.7	-0.9	-0.1	0.9	0.9	1.4	0.5
Bone: cortical apparent density	1.5	2.3	3.0	1.6	1.6	-1.6	-1.4	-1.7	-1.7	-1.2	1.7	1.5	1.3	-1.3
Bone: cortical area	0.2	0.3	0.5	-0.6	-0.6	0.6	0.7	0.7	0.6	0.3	-0.2	-0.4	-0.5	0.3
Bone: cortical porosity	0.4	0.4	2.7	-0.0	-0.1	0.1	-0.2	0.1	0.2	-1.1	-0.3	-0.5	-0.8	-1.7
Bone: cortical porosity	0.7	0.8	1.5	-0.7	-0.8	0.8	0.4	0.8	0.9	-0.4	-1.1	-1.0	-1.2	-1.0
Bone: cortical thickness	1.7	2.8	3.6	1.8	1.8	-1.8	-1.7	-1.6	-1.7	-1.7	1.9	1.7	1.4	-1.4
Bone: cortical thickness	3.1	3.8	4.4	2.1	2.1	-2.1	-1.9	-2.1	-2.1	-1.8	2.1	2.0	2.0	-1.3
Bone: cortical tissue density	1.2	2.0	2.7	1.5	1.5	-1.5	-1.3	-1.6	-1.6	-1.1	1.5	1.4	1.2	-1.2
Condit. Reinf. active minus inactive responses	0.1	0.1	0.6	0.2	0.1	-0.2	-0.3	-0.2	-0.2	-0.6	0.3	0.3	0.8	-0.3
Condit. Reinf. active-inactive response ratio	0.5	0.5	1.2	0.6	0.5	-0.6	-0.7	-0.7	-0.6	-1.1	0.5	0.6	0.9	-0.8
Condit. Reinf. active responses	0.4	0.5	1.8	0.5	0.4	-0.6	-0.6	-0.5	-0.6	-0.6	0.9	0.9	1.3	-0.3
Condit. Reinf. inactive responses	1.4	1.9	3.4	1.3	1.2	-1.4	-1.3	-1.1	-1.4	-0.8	1.8	1.8	1.8	-0.6
Incentive salience index mean	0.6	0.7	1.9	-0.8	-0.9	0.8	0.8	1.1	0.9	0.8	-0.5	-0.5	-0.0	1.4
Condit. Reinf. lever presses	1.9	2.9	7.7	-1.5	-1.6	1.5	1.6	2.0	1.6	2.3	-1.0	-1.2	-0.7	2.8
Condit. Reinf. active minus inactive responses	0.4	0.7	1.7	-0.8	-0.8	0.8	0.6	0.6	0.8	0.0	-1.3	-0.9	-1.1	-0.5
Condit. Reinf. active-inactive response ratio	1.4	2.3	6.6	-1.3	-1.3	1.5	1.2	1.3	1.5	0.7	-2.0	-1.8	-2.6	0.1
Condit. Reinf. active responses	0.1	0.1	0.4	-0.2	-0.2	0.2	0.1	-0.0	0.1	-0.2	-0.5	-0.2	0.0	-0.6
Condit. Reinf. inactive responses	0.7	1.1	4.5	0.6	0.6	-0.8	-0.6	-1.0	-1.0	-0.7	1.1	1.2	2.1	-0.7
Condit. Reinf. lever presses	0.1	0.1	0.3	0.1	0.1	-0.1	-0.3	-0.2	-0.1	-0.4	-0.4	0.1	0.3	-0.6
Condit. Reinf. lever reinforcers received	0.1	0.1	0.4	-0.3	-0.3	0.3	0.2	0.1	0.3	-0.2	-0.7	-0.3	-0.0	-0.6
Conditioned reinforcement - actives	0.1	0.2	0.5	0.5	0.5	-0.4	-0.4	-0.5	-0.4	-0.5	0.7	0.7	0.4	-0.3
Conditioned reinforcement - inactives	0.2	0.5	0.8	0.8	0.8	-0.7	-0.8	-0.7	-0.6	-0.8	0.5	0.3	0.7	-0.9
Conditioned locomotion	0.1	0.1	0.2	-0.3	-0.3	0.5	0.2	0.3	0.4	0.4	-0.3	-0.2	-0.4	0.0
Patch foraging indifference point 0 sec	1.1	3.2	5.3	1.7	1.6	-1.8	-1.6	-2.1	-1.8	-1.9	1.7	0.6	1.9	-2.3
Patch foraging indifference point AUC	0.1	0.3	0.7	-0.4	-0.4	0.5	0.2	0.7	0.6	-0.1	-0.6	-0.8	-0.6	-0.7
Delay disc. indifference point, 0s delay	0.7	0.8	1.7	-0.7	-0.8	0.8	0.8	1.0	0.9	1.0	-1.0	-1.3	-0.6	0.8
Delay disc. indifference point, 16s delay	1.1	1.5	3.1	1.8	1.6	-1.4	-1.7	-1.2	-1.2	-1.3	0.7	0.2	0.1	-1.1
Delay disc. indifference point, 2s delay	1.1	1.2	3.1	-0.9	-0.9	0.9	0.8	1.0	1.2	0.7	-1.6	-1.8	-1.0	0.1
Delay disc. indifference point, 24s delay	0.2	0.3	1.1	0.7	0.5	-0.5	-0.7	-0.5	-0.3	-0.8	-0.1	-0.4	-0.2	-1.0
Delay disc. indifference point, 4s delay	0.9	1.0	1.6	-1.1	-1.3	1.2	1.1	1.0	1.1	0.4	-0.9	-1.0	-0.8	-0.7
Delay disc. indifference point, 8s delay	0.0	0.0	0.2	0.1	0.2	-0.2	-0.2	0.2	0.1	-0.1	-0.2	-0.4	-0.2	-0.1
Indifference point function ln k	0.2	0.5	0.8	-0.7	-0.7	0.6	0.6	0.8	0.8	0.7	-0.7	-0.9	-0.7	0.6
Indifference point function log k	0.2	0.5	0.8	-0.7	-0.7	0.6	0.6	0.8	0.8	0.7	-0.7	-0.9	-0.7	0.6
Patch foraging total patch changes 0 sec	1.2	3.6	6.0	1.8	1.8	-2.0	-1.8	-2.3	-1.9	-2.0	1.7	0.7	1.9	-2.5
Patch foraging total patch changes 12 sec	1.7	2.3	4.5	1.6	1.6	-1.5	-1.6	-1.7	-1.5	-1.7	1.0	0.4	1.4	-2.1
Patch foraging total patch changes 18 sec	2.5	5.8	7.4	2.6	2.6	-2.6	-2.5	-2.7	-2.7	-2.3	2.1	1.7	2.2	-2.1
Patch foraging total patch changes 24 sec	1.8	6.1	8.0	2.8	2.8	-2.8	-2.7	-2.7	-2.7	-2.3	2.4	1.7	2.2	-1.8
Patch foraging total patch changes 6 sec	2.7	4.6	5.9	2.3	2.2	-2.3	-2.2	-2.4	-2.2	-2.1	1.8	1.5	2.4	-2.2
Patch foraging time to switch 0 sec	0.5	1.8	3.4	1.5	1.4	-1.4	-1.1	-1.5	-1.5	-0.4	1.2	1.7	1.8	0.4
Patch foraging water rate 0 sec	0.1	0.2	1.6	0.2	0.2	-0.1	-0.2	0.1	0.1	0.0	-0.4	-1.3	-0.7	-0.0
Patch foraging water rate 12 sec	0.2	0.8	1.3	1.1	1.1	-1.0	-1.1	-0.9	-1.0	-1.0	1.0	0.6	0.2	-0.6
Patch foraging water rate 18 sec	0.1	0.1	0.3	-0.5	-0.5	0.4	0.5	0.3	0.2	0.1	0.3	-0.2	-0.2	-0.3
Patch foraging water rate 24 sec	0.1	0.1	0.3	0.1	0.1	-0.1	-0.0	0.1	-0.2	-0.4	0.6	-0.2	-0.0	-0.5
Patch foraging water rate 6 sec	0.4	0.6	1.1	1.0	1.0	-1.0	-1.0	-0.7	-0.8	-0.8	0.7	0.1	-0.0	-0.4
Seeking ratio, delayed vs. immediate footshock	0.2	0.3	1.9	-0.5	-0.5	0.4	0.4	0.2	0.3	-0.5	0.2	-0.3	0.0	-1.4
Distance traveled before self-admin	0.6	1.2	2.2	-1.4	-1.5	1.3	1.5	1.1	1.1	1.3	-0.6	-0.3	-0.5	0.7
Distance traveled after self-admin	0.6	1.1	2.1	-1.4	-1.5	1.3	1.3	0.8	1.1	0.7	-0.8	-0.6	-0.6	-0.5
Extensor digitorum longus weight	0.3	1.1	1.9	-1.3	-1.4	1.2	1.4	1.1	1.1	1.1	-0.7	-0.8	-0.5	0.9
Bone: elastic displacement	0.8	1.0	3.0	0.9	0.9	-0.9	-0.9	-0.9	-0.9	-1.2	0.8	1.0	0.6	-1.7
Bone: elastic work	0.1	0.1	0.7	0.1	0.1	-0.2	-0.1	-0.1	-0.1	-0.5	-0.0	0.4	0.4	-0.8
Bone: endosteal estimation	5.6	13.7	19.0	-4.4	-4.3	4.3	4.3	3.7	3.9	3.0	-3.5	-3.4	-3.1	2.0
Bone: endosteal perimeter	4.4	10.9	13.5	-3.7	-3.7	3.6	3.6	3.4	3.5	2.9	-3.1	-3.1	-2.9	2.7
Epididymis fat weight	6.7	33.7	43.5	6.6	6.5	-6.5	-6.0	-6.6	-6.4	-5.0	5.5	5.6	5.1	-3.2
Delta time in closed arm before/after self-admin	0.2	0.2	0.6	0.1	0.1	-0.0	-0.0	-0.0	0.1	0.4	-0.3	-0.7	-0.6	0.7
Delta time in open arm before/after self-admin	0.3	0.3	1.4	-0.5	-0.3	0.3	0.3	-0.0	-0.0	-0.4	0.5	0.9	0.9	-1.2
Diff in mean of infusions in LGA sessions	0.4	0.7	1.9	1.4	0.9	-1.3	-1.3	-0.8	-0.8	-0.2	0.4	-0.3	-0.2	0.8
Delay discount exponential model param	0.1	0.2	0.8	0.0	0.2	-0.2	0.0	-0.3	-0.4	0.1	0.5	0.9	0.5	0.6
Extinction: sum of active levers before priming	0.4	0.6	2.4	0.2	-0.0	-0.0	-0.1	0.2	0.3	0.4	-1.0	-1.3	-1.6	0.7
Active lever presses in extinction session 6	1.1	1.1	1.5	1.2	1.0	-1.1	-1.1	-1.2	-1.1	-1.0	0.7	0.8	1.2	-0.8
Bone: final force	0.2	0.3	1.1	0.3	0.3	-0.3	-0.0	-0.4	-0.4	-0.3	0.7	0.7	1.0	-0.2
Bone: final moment	0.1	0.2	0.9	0.1	0.1	-0.2	0.1	-0.3	-0.4	-0.3	0.8	0.6	1.0	-0.3
Food consumed during 24 hour testing period	0.8	1.6	3.1	-1.5	-1.5	1.4	1.8	1.4	1.2	1.6	-0.0	-0.8	-0.1	1.2
Glucose	6.3	9.9	11.4	-3.2	-3.3	3.3	3.1	3.4	3.3	3.2	-2.7	-3.4	-3.2	2.5
Heart weight	0.3	0.4	1.4	-0.2	-0.2	0.2	0.2	0.1	0.6	-0.2	-1.2	-1.1	-1.1	-0.7
Delay discount hyperbolic model param	0.2	0.2	0.9	0.0	0.2	-0.2	0.0	-0.3	-0.4	0.2	0.7	1.0	0.5	0.7
Intermittent access intake day 1-15 change	0.0	0.1	0.9	-0.2	-0.2	0.2	0.1	0.0	-0.1	-0.1	0.1	0.7	0.9	-0.4
Intermittent access intake escalation	0.1	0.8	2.6	0.1	0.2	-0.1	-0.3	-0.5	-0.6	-0.9	0.9	1.3	1.6	-1.3
Intermittent access intake escalation 2	0.5	0.8	1.8	-1.3	-1.3	1.3	1.1	1.0	0.7	0.5	-0.1	0.2	0.4	-0.3
Intermitt. access day 1 inactive lever presses	0.2	3.1	5.5	-1.4	-1.4	1.5	1.4	1.8	1.8	1.7	-2.3	-2.1	-1.9	1.8
Intermitt. access day 15 inactive lever presses	0.1	0.3	0.5	-0.6	-0.6	0.6	0.7	0.6	0.6	0.4	-0.5	0.1	-0.7	0.1
Intermitt. access escalation Index	0.0	0.1	0.8	-0.0	-0.0	-0.0	-0.1	0.3	0.2	0.5	-0.4	-0.2	0.4	0.9
Intermittent access day 1 total infusions	0.3	1.0	1.5	1.1	1.1	-1.2	-1.0	-1.1	-0.9	-0.9	1.0	1.1	0.7	-0.6
Intermittent access day 15 total infusions	0.5	1.3	2.5	0.7	0.7	-0.8	-0.8	-1.0	-1.0	-1.2	1.3	1.5	1.6	-1.3
Intermittent access terminal intake (last 3 days)	0.6	1.0	1.9	0.9	0.9	-0.8	-0.9	-1.0	-0.8	-1.2	0.9	1.0	1.1	-1.4
Intermittent access total infusions	0.7	0.8	1.4	0.7	0.7	-0.7	-0.7	-0.9	-0.7	-1.0	1.1	1.0	0.9	-1.2
Intermittent access day 1 locomotion	0.1	0.2	0.9	-0.0	-0.0	-0.1	0.1	-0.4	-0.3	-0.2	0.8	1.0	0.7	-0.2
Intermittent access day 15 total locomotion	0.1	0.5	0.9	-1.0	-1.0	1.0	0.9	0.5	0.5	0.5	0.2	0.6	0.4	-0.4
Intermittent access total locomotion	0.3	0.4	0.8	-0.8	-0.7	0.7	0.6	0.2	0.2	0.1	0.7	0.9	0.5	-0.8
Intermittent access standard deviation	0.1	0.6	1.0	0.6	0.6	-0.5	-0.5	-1.0	-0.7	-0.8	0.8	0.9	0.5	-1.0
Left kidney weight	0.1	0.8	2.6	-1.2	-1.2	1.1	1.6	0.4	0.4	0.1	0.5	0.2	0.5	-1.2
Right kidney weight	0.2	1.6	5.2	-1.8	-1.8	1.6	2.3	0.8	0.8	0.8	0.5	0.3	0.8	-0.6
Cocaine induced anxiety	0.3	0.9	1.4	-1.0	-1.0	0.9	0.9	1.0	0.9	1.0	-0.8	-1.0	-0.6	1.2
Post-drug Anxiety	0.2	0.2	0.7	-0.3	-0.3	0.2	0.2	0.3	0.3	0.3	-0.6	-0.9	-0.8	0.2
Baseline Anxiety	0.9	1.4	2.9	1.7	1.7	-1.5	-1.6	-1.4	-1.1	-1.0	-0.0	0.2	-0.4	-0.8
Tail length	2.1	11.5	20.5	-4.5	-4.5	4.4	4.5	3.6	3.7	2.3	-2.4	-2.7	-1.4	-0.1
Length with tail	4.0	17.6	32.9	-5.6	-5.6	5.3	5.7	4.5	4.5	3.4	-2.4	-3.0	-1.7	0.7
Length without tail	1.6	8.4	15.9	-3.6	-3.5	3.3	4.0	2.9	2.9	3.2	-1.6	-2.0	-1.4	2.2
Times rat made contact with spout	4.2	4.9	8.1	1.9	1.9	-2.0	-2.1	-2.0	-2.1	-2.4	2.1	2.2	2.4	-2.8
Lifetime Intake	0.4	0.5	0.9	0.5	0.5	-0.5	-0.6	-0.8	-0.5	-0.8	0.9	0.9	0.8	-0.9
Liver weight, left	4.2	7.3	11.9	-3.2	-3.3	3.1	3.4	2.7	2.8	2.6	-1.6	-2.2	-1.6	2.2
Liver weight, right	5.0	8.7	13.3	-3.6	-3.6	3.5	3.7	3.2	3.2	2.8	-2.0	-2.5	-1.9	1.8
Locomotor activity	3.1	4.9	9.3	-3.0	-3.0	3.0	2.7	2.3	2.3	1.3	-1.6	-1.6	-1.3	-0.3
Locomotor testing distance	0.7	1.8	2.7	-1.6	-1.6	1.6	1.5	1.3	1.3	1.1	-1.3	-1.3	-1.2	0.3
Locomotor testing rearing	0.4	1.5	2.8	-1.6	-1.6	1.6	1.7	1.2	1.2	1.2	-0.8	-0.4	-0.8	0.4
Locomotion in novel chamber	0.0	0.1	0.1	-0.3	-0.3	0.3	0.3	0.3	0.2	0.0	0.3	-0.1	0.1	-0.1
Locomotion in novel chamber post-restriction	0.1	0.2	0.4	0.3	0.3	-0.2	-0.3	-0.5	-0.4	-0.3	0.2	0.6	0.5	-0.5
Fecal boli incidents, locomotor time 1	0.1	0.1	0.5	0.2	0.2	-0.5	-0.1	-0.7	-0.5	-0.1	0.4	0.1	0.4	-0.3
Change in fecal boli incidents, locomotor task	1.2	1.3	2.7	-0.4	-0.4	0.7	0.4	1.0	1.1	1.1	-1.6	-1.6	-1.6	1.5
Time >=10cm from walls, locomotor time 1	2.0	2.4	3.4	-1.7	-1.5	1.6	1.8	1.3	1.4	1.8	-1.2	-1.6	-1.4	1.8
Bouts of movement, locomotor time 1	0.2	0.2	0.6	-0.8	-0.5	0.6	0.5	0.7	0.4	0.5	0.1	0.2	0.1	0.1
Total resting periods, locomotor time 1	0.4	0.4	0.9	-1.0	-0.8	0.8	0.8	0.8	0.6	0.7	-0.1	-0.0	0.1	0.2
Rest time, locomotor task time 1	0.7	1.1	2.1	-1.4	-1.4	1.4	1.4	1.1	1.1	0.8	-0.6	-0.7	-0.1	0.1
Distance moved, locomotor task time 1	0.1	0.2	0.6	0.7	0.8	-0.6	-0.6	-0.5	-0.4	-0.4	0.0	0.2	-0.1	-0.2
Vertical activity count, locomotor time 1	0.0	0.3	0.5	0.7	0.7	-0.6	-0.6	-0.6	-0.6	-0.5	0.5	0.5	-0.2	-0.0
Time >=10cm from walls, locomotor time 2	0.5	1.4	2.4	-1.0	-0.7	1.0	1.1	0.8	1.1	1.2	-1.4	-1.5	-1.3	1.4
Bouts of movement, locomotor time 2	0.5	1.8	4.7	-2.2	-1.8	1.8	1.8	1.6	1.3	0.5	-0.3	-0.4	0.5	-0.4
Total resting periods, locomotor time 2	0.6	2.6	6.0	-2.4	-2.1	2.2	2.1	2.0	1.7	0.8	-0.7	-0.8	0.2	-0.3
Rest time, locomotor task time 2	2.8	4.7	7.2	-2.5	-2.7	2.6	2.7	2.5	2.2	2.4	-1.5	-1.0	-0.9	1.9
Distance moved, locomotor task time 2	1.2	1.6	2.8	1.7	1.7	-1.6	-1.4	-1.6	-1.4	-1.1	0.8	0.7	0.6	-0.5
Vertical activity count, locomotor time 2	0.3	0.8	1.5	1.2	1.2	-1.1	-1.2	-1.1	-1.0	-0.7	0.3	0.0	-0.2	-0.1
Light reinforcement 1	0.1	0.5	1.0	1.0	0.9	-0.9	-0.8	-0.8	-0.8	-0.1	0.3	-0.3	0.7	0.5
Light reinforcement 2	0.4	0.9	1.6	-1.0	-1.0	0.9	1.2	0.9	0.7	1.3	-0.2	-0.6	-0.3	1.3
Bone: marrow area	5.4	13.1	18.5	-4.3	-4.3	4.2	4.3	3.6	3.9	2.9	-3.4	-3.3	-3.0	1.9
Bone: maximum diameter	3.1	6.2	7.4	-2.6	-2.7	2.6	2.6	2.7	2.7	2.1	-2.3	-2.3	-2.5	2.0
Bone: maximum force	0.1	0.1	0.4	-0.3	-0.3	0.2	0.5	0.1	0.1	0.1	0.4	0.3	0.7	0.2
Bone: maximum moment	0.1	0.2	0.5	-0.5	-0.5	0.4	0.7	0.3	0.2	0.1	0.4	0.2	0.5	0.1
Mean time between licks in bursts	0.9	5.2	7.0	-2.6	-2.6	2.5	2.5	2.6	2.4	2.1	-1.8	-2.2	-2.1	1.4
Mean num. licks in bursts	2.3	6.1	10.5	1.9	1.9	-2.1	-1.8	-2.3	-2.4	-2.5	3.2	2.8	2.9	-2.8
Cd content in liver	0.8	0.9	1.5	1.0	1.0	-1.0	-0.7	-1.0	-1.1	-0.3	1.2	1.2	1.2	0.1
Co content in liver	1.1	1.2	2.1	1.4	1.4	-1.3	-1.2	-1.4	-1.2	-0.9	0.8	0.9	0.7	-0.5
Cu content in liver	3.5	4.2	5.3	2.2	2.2	-2.2	-2.3	-2.1	-2.1	-2.1	1.9	1.9	1.6	-1.8
Fe content in liver	0.8	1.0	1.4	1.0	1.0	-1.0	-0.8	-1.1	-1.1	-1.0	1.2	1.0	0.7	-0.9
K content in liver	0.3	0.3	0.7	0.9	0.8	-0.8	-0.8	-0.3	-0.5	-0.2	0.4	0.2	0.2	0.4
Mg content in liver	1.2	1.3	3.3	-0.6	-0.6	0.8	0.6	1.2	1.1	1.3	-1.3	-1.4	-1.2	1.8
Mn content in liver	4.4	4.9	8.5	-2.1	-2.1	2.2	2.1	2.2	2.2	2.6	-2.1	-2.1	-1.5	2.9
Na content in liver	0.9	1.0	2.0	1.3	1.3	-1.2	-1.4	-0.8	-0.9	-1.2	0.5	0.7	0.6	-0.6
Rb content in liver	0.2	0.2	1.1	0.5	0.5	-0.5	-0.4	-0.2	-0.3	0.5	0.4	0.2	0.4	1.0
Se content in liver	3.6	4.3	5.9	-2.3	-2.3	2.3	2.0	2.4	2.4	1.5	-2.3	-2.2	-1.7	1.0
Sr content in liver	0.8	0.7	1.1	-1.0	-1.0	1.0	1.0	0.8	0.8	0.9	-0.8	-0.6	-0.4	0.6
Zn content in liver	0.2	0.2	0.5	-0.4	-0.4	0.4	0.5	0.5	0.4	0.7	-0.2	-0.5	-0.2	0.7
Bone: minimum diameter	3.6	6.8	8.9	-3.0	-2.9	2.9	3.0	2.8	2.8	2.5	-2.4	-2.3	-1.7	2.2
Time in familiar zone, hab. session 1	4.8	5.3	7.0	2.2	2.1	-2.3	-2.4	-2.3	-2.3	-2.2	2.2	2.6	2.5	-2.2
Time in novel zone, hab. session 1	3.2	3.6	5.0	-1.9	-1.9	2.0	2.1	1.8	1.9	1.7	-1.7	-2.2	-1.8	1.6
Total zone transitions, hab. session 1	0.1	0.2	0.5	0.5	0.6	-0.4	-0.5	-0.2	-0.3	0.1	-0.0	0.3	0.5	0.7
Total locomotion distance, hab. session 1	0.2	0.3	0.9	0.7	0.7	-0.7	-0.6	-0.4	-0.4	-0.0	-0.0	0.4	0.6	1.0
Locomotion velocity, hab. session 1	0.2	0.4	0.7	0.8	0.8	-0.8	-0.8	-0.5	-0.5	-0.2	-0.0	0.3	0.4	0.7
Time in familiar zone, hab. session 2	1.1	1.3	2.3	0.9	0.8	-0.9	-0.9	-1.1	-1.1	-1.1	1.5	1.4	1.5	-1.0
Time in novel zone, hab. session 2	0.2	0.2	0.6	-0.4	-0.4	0.4	0.4	0.4	0.4	0.3	-0.6	-0.8	-0.8	0.0
Total zone transitions, hab. session 2	0.2	0.3	0.7	0.7	0.7	-0.6	-0.6	-0.3	-0.3	0.1	-0.5	0.3	0.6	0.8
Total locomotion distance, hab. session 2	0.6	0.7	2.2	1.0	1.0	-1.0	-0.9	-0.5	-0.6	0.2	-0.2	0.6	1.1	1.5
Locomotion velocity, hab. session 2	0.5	0.7	2.9	0.9	0.9	-0.9	-0.9	-0.3	-0.4	0.3	-0.4	0.5	1.0	1.7
Novel to familiar place preference ratio	0.1	0.2	0.4	0.6	0.6	-0.6	-0.7	-0.3	-0.3	-0.5	-0.0	0.0	-0.3	-0.3
Novelty place preference	0.1	0.1	0.2	0.3	0.3	-0.3	-0.4	-0.1	-0.1	-0.4	-0.2	-0.1	-0.5	-0.4
Time in novel zone, NPP test	0.1	0.1	0.3	0.2	0.2	-0.2	-0.3	0.0	0.1	-0.4	-0.3	-0.3	-0.5	-0.4
Total zone transitions, NPP test	0.2	0.3	1.6	0.5	0.5	-0.4	-0.4	-0.1	-0.3	0.4	-0.2	0.3	0.8	1.3
Total locomotion distance, NPP test	0.7	0.9	2.5	1.1	1.1	-1.2	-1.0	-0.7	-0.8	0.1	0.4	0.7	1.1	1.6
Locomotion velocity, NPP test	0.9	1.3	2.7	1.4	1.4	-1.4	-1.2	-0.8	-1.0	0.1	0.6	0.8	1.2	1.6
Intraocular pressure	0.3	0.5	2.1	0.4	0.4	-0.5	-0.3	-0.7	-0.9	-0.5	1.4	0.6	1.0	-0.5
Delta distance traveled before/after self-admin	0.3	0.3	2.2	-0.1	-0.1	0.1	-0.1	-0.2	0.1	-0.7	-0.4	-0.6	-0.4	-1.5
Delta ambulatory time before/after self-admin	0.2	0.3	0.9	-0.5	-0.4	0.5	0.3	0.3	0.5	-0.3	-0.7	-1.0	-0.6	-0.9
Parametrial fat weight	0.2	0.5	2.3	-0.3	-0.3	0.1	0.7	-0.3	-0.5	0.3	1.5	1.1	0.9	0.2
Pavlov. Cond. lever latency	3.5	4.4	7.4	2.2	2.2	-2.3	-2.0	-2.7	-2.4	-2.0	1.7	1.9	1.8	-1.7
Pavlov. Cond. magazine entry latency	2.1	2.6	4.0	-1.9	-1.9	1.9	1.6	2.0	1.9	1.1	-1.5	-1.6	-1.6	0.4
Pavlov. Cond. change in total contacts	2.1	2.3	3.9	-1.8	-1.8	1.8	1.6	2.0	1.8	1.0	-1.3	-1.3	-1.3	0.3
Pavlov. Cond. index score	3.6	4.6	7.3	-2.4	-2.3	2.4	2.1	2.7	2.4	1.8	-1.8	-2.0	-1.9	1.5
Pavlov. Cond. latency score	3.9	5.0	8.2	-2.4	-2.4	2.4	2.2	2.9	2.5	1.9	-1.9	-2.1	-2.0	1.6
Pavlov. Cond. lever contacts	4.1	5.0	7.6	-2.2	-2.2	2.3	2.2	2.8	2.4	2.3	-1.9	-2.0	-1.9	2.2
Pavlov. Cond. magazine entry number	1.2	1.5	2.2	1.5	1.4	-1.5	-1.2	-1.5	-1.4	-0.8	1.2	1.2	1.1	-0.4
Pavlov. Cond. intertrial magazine entries	3.3	3.9	5.8	2.1	2.0	-2.1	-1.9	-2.2	-2.2	-1.4	2.4	2.0	1.9	-1.2
Pavlov. Cond. lever-magazine prob. diff.	3.2	4.0	6.5	-2.2	-2.2	2.2	1.9	2.5	2.2	1.7	-1.6	-1.9	-1.7	1.4
Pavlov. Cond. response bias	2.6	3.2	4.9	-2.0	-2.0	2.0	1.8	2.2	2.0	1.6	-1.5	-1.7	-1.5	1.2
Pavlov. Cond. lever latency	0.5	0.7	1.2	-0.7	-0.7	0.7	0.9	0.9	0.8	1.1	-0.4	-0.9	-0.9	1.1
Pavlov. Cond. magazine entry latency	0.3	0.4	1.0	-0.7	-0.7	0.8	0.6	0.8	0.7	0.5	-1.0	-0.5	-0.4	0.2
Pavlov. Cond. change in total contacts	0.1	0.3	0.8	0.3	0.3	-0.2	-0.5	-0.3	-0.2	-0.9	-0.7	0.1	-0.2	-0.9
Pavlov. Cond. index score	0.0	0.1	0.3	-0.2	-0.2	0.2	0.0	0.1	0.1	-0.2	-0.6	0.0	0.1	-0.6
Pavlov. Cond. latency score	0.1	0.1	0.5	0.0	0.0	0.0	-0.2	-0.1	-0.0	-0.4	-0.5	0.2	0.2	-0.7
Pavlov. Cond. lever contacts	0.3	0.5	0.9	0.6	0.6	-0.6	-0.7	-0.8	-0.7	-0.9	0.2	0.7	0.6	-0.9
Pavlov. Cond. magazine entry number	0.1	0.1	0.4	0.3	0.3	-0.3	-0.2	-0.3	-0.3	-0.2	0.6	-0.0	0.0	-0.1
Pavlov. Cond. intertrial magazine entries	0.4	0.8	1.3	-1.1	-1.1	1.0	1.1	1.1	1.1	0.8	-0.5	-0.8	-0.3	0.6
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.1	0.3	-0.1	-0.1	0.2	-0.0	0.0	0.1	-0.3	-0.6	0.1	0.2	-0.5
Pavlov. Cond. response bias	0.0	0.0	0.2	-0.1	-0.1	0.2	-0.0	0.1	0.0	-0.3	-0.4	0.1	0.1	-0.4
Time in closed arm before self-admin	0.1	0.1	0.6	-0.0	0.1	0.0	0.0	0.1	0.2	0.2	-0.8	-0.5	-0.4	0.3
Time in closed arm after self-admin	0.3	0.3	0.9	0.9	1.0	-0.8	-0.8	-0.5	-0.5	-0.2	-0.3	-0.3	-0.0	0.2
Time in open arm before self-admin	0.1	0.2	0.4	-0.5	-0.7	0.5	0.4	0.5	0.5	0.0	-0.1	-0.3	-0.5	-0.1
Time in open arm after self-admin	0.4	0.4	1.0	-1.0	-0.9	0.9	0.7	0.4	0.6	-0.1	0.0	0.1	-0.1	-0.9
Bone: periosteal estimation	2.6	6.3	8.9	-3.0	-3.0	3.0	3.0	2.5	2.7	1.9	-2.2	-2.3	-2.1	1.3
Bone: periosteal perimeter	2.2	4.4	5.8	-2.4	-2.4	2.4	2.3	2.3	2.3	1.6	-1.9	-1.9	-1.9	1.4
Bone: post-yield work	2.6	4.4	6.1	-2.4	-2.4	2.4	2.5	2.1	2.0	2.3	-1.3	-1.6	-1.4	2.1
Progressive ratio test 1 active lever presses	0.2	0.4	0.9	0.8	0.8	-0.9	-0.7	-0.8	-0.5	-0.6	0.4	0.4	0.6	0.1
Progressive ratio test 1 breakpoint	0.2	0.4	0.8	0.8	0.8	-0.9	-0.7	-0.8	-0.5	-0.6	0.3	0.3	0.5	0.2
Progressive ratio test 1 inactive lever presses	0.6	1.6	3.0	1.7	1.7	-1.6	-1.5	-1.5	-1.4	-1.0	0.8	1.0	0.5	0.2
Progressive ratio test 2 active lever presses	0.7	0.9	1.3	1.0	1.0	-1.0	-1.0	-0.9	-0.9	-0.9	0.9	1.2	1.1	-0.5
Progressive ratio test 2 breakpoint	0.9	1.1	1.6	1.1	1.1	-1.1	-1.1	-1.0	-1.0	-1.0	1.0	1.3	1.1	-0.6
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.2	-0.2	-0.2	0.2	0.3	0.3	0.4	0.4	-0.4	-0.3	-0.3	0.5
Incentive Sensitization - Responses	0.1	0.3	1.0	0.5	0.5	-0.4	-0.6	-0.4	-0.4	-0.6	0.2	1.0	0.7	-0.7
Incentive Sensitization - Breakpoint	0.2	0.5	1.4	0.6	0.5	-0.5	-0.7	-0.5	-0.5	-0.6	0.4	1.2	0.8	-0.7
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	-0.0	-0.4	0.1	0.1	0.0	0.2	0.0	-0.5	-0.4	-0.3	-0.4
Progressive ratio	0.1	0.4	1.6	-0.1	-0.1	0.0	0.3	-0.5	-0.2	-0.6	0.6	0.9	0.9	-1.2
Food seeking constrained by brief footshock	0.2	0.3	1.0	0.2	0.2	-0.4	-0.2	-0.4	-0.4	-0.6	0.7	0.6	0.7	-1.0
Seeking ratio, punishment vs. effort	0.1	0.3	0.9	0.3	0.3	-0.2	-0.5	0.3	0.1	0.2	-0.5	-0.9	-0.9	0.6
Retroperitoneal fat weight	0.1	0.3	1.0	-0.2	-0.2	0.1	0.4	-0.0	-0.3	0.3	1.0	0.8	0.9	-0.1
Reaction time number correct	0.6	2.1	3.4	1.7	1.7	-1.7	-1.6	-1.8	-1.7	-1.6	1.2	0.5	0.4	-1.1
Reaction time mean minus median	1.0	6.2	12.1	-3.4	-3.5	3.3	3.3	3.0	2.5	2.3	-0.6	0.4	-0.4	1.3
Reaction time mean minus median AUC	0.6	4.0	7.6	-2.7	-2.8	2.6	2.6	2.5	2.0	1.9	-0.4	0.4	-0.4	1.2
Reaction time num false alarms	0.3	0.5	1.6	-0.5	-0.5	0.6	0.4	0.9	0.8	0.5	-1.3	-0.8	-0.9	0.2
Reaction time num false alarms AUC	0.4	0.9	2.5	-0.6	-0.5	0.6	0.4	1.0	1.0	0.4	-1.6	-1.4	-1.3	0.0
Reaction time trials correct on left	0.6	2.1	3.4	1.7	1.7	-1.7	-1.6	-1.8	-1.7	-1.6	1.2	0.5	0.4	-1.1
Reaction time trials on left	0.5	1.8	3.0	1.6	1.6	-1.6	-1.5	-1.7	-1.6	-1.5	1.1	0.4	0.3	-1.0
Reaction time mean	2.8	6.3	9.1	-3.0	-3.0	3.0	2.9	2.9	2.5	2.8	-1.5	-0.7	-1.3	2.5
Reaction time mean AUC	2.5	6.1	9.4	-3.0	-3.1	3.0	3.0	2.9	2.5	2.7	-1.3	-0.6	-1.1	2.4
Median of all reaction times	2.7	4.2	6.0	-2.2	-2.2	2.3	2.2	2.3	2.0	2.4	-1.5	-0.9	-1.3	2.4
Reaction time omissions	2.7	4.4	7.1	-2.6	-2.7	2.5	2.6	2.5	2.1	2.2	-1.3	-0.7	-1.2	1.5
Reaction time false alarm rate	1.8	2.5	5.1	-1.5	-1.5	1.5	1.3	2.0	1.9	1.2	-2.2	-1.5	-1.5	0.7
Reaction time premature initiation rate	0.0	0.1	0.3	-0.1	-0.1	0.1	0.3	0.1	0.2	0.4	-0.6	-0.2	-0.3	0.3
Reaction time premature initiations	0.1	0.4	0.9	0.8	0.9	-0.9	-0.6	-1.0	-0.7	-0.5	0.0	0.0	-0.2	-0.4
Std. dev. reaction times	2.3	7.5	13.2	-3.6	-3.6	3.5	3.4	3.3	2.9	2.5	-1.5	-0.7	-1.4	1.5
Reaction time trials completed	0.5	1.8	3.0	1.6	1.6	-1.6	-1.5	-1.7	-1.6	-1.5	1.1	0.4	0.3	-1.0
Reaction time trials AUC	0.5	1.9	3.1	1.6	1.7	-1.6	-1.5	-1.8	-1.6	-1.4	1.2	0.4	0.3	-0.9
Run reversals in cocaine runway, females	0.8	0.9	1.6	1.1	1.1	-1.1	-1.0	-1.3	-1.1	-0.8	0.6	1.2	0.5	-0.3
Run reversals in cocaine runway, males	3.1	3.5	6.6	-2.5	-2.5	2.3	2.6	2.2	1.9	1.7	-0.7	-0.6	-0.7	0.6
Latency to leave start box in cocaine runway	0.4	0.5	2.1	0.1	0.1	0.0	-0.0	0.6	0.5	0.8	-0.8	-0.9	-1.0	1.4
Latency to leave start box in cocaine runway, F	0.2	0.3	1.0	0.1	0.0	0.1	-0.0	0.5	0.3	0.6	-0.6	-0.5	-0.8	1.0
Latency to leave start box in cocaine runway, M	0.2	0.2	0.8	-0.0	-0.0	0.1	0.2	0.4	0.4	0.5	-0.3	-0.8	-0.5	0.9
Std. dev. time between licks in bursts	3.7	7.0	9.1	-2.5	-2.5	2.6	2.5	2.7	2.8	2.5	-3.0	-3.0	-3.0	1.7
Total sessions with >9 infusions	0.3	0.4	1.2	0.4	0.4	-0.4	-0.5	-0.6	-0.4	-0.8	0.5	1.1	0.8	-0.8
Short access day 1 total inactive lever presses	1.0	2.1	3.0	-1.7	-1.7	1.7	1.7	1.7	1.6	1.2	-1.1	-0.8	-1.2	0.6
Short access day 10 total inactive lever presses	0.0	0.2	0.9	-0.1	-0.1	-0.0	0.1	0.4	0.2	0.4	-0.3	-0.1	-0.7	1.0
Short access day 1 total infusions	0.0	0.1	0.3	0.3	0.3	-0.2	-0.3	-0.4	-0.1	-0.2	0.1	0.5	0.4	-0.0
Short access day 10 total infusions	0.3	0.6	1.1	0.6	0.6	-0.5	-0.6	-0.7	-0.7	-0.6	1.0	0.9	1.0	-0.7
Short access total infusions	0.3	0.4	0.6	0.6	0.6	-0.6	-0.6	-0.7	-0.5	-0.6	0.6	0.7	0.8	-0.5
Short access day 1 locomotion	0.1	0.2	0.5	0.6	0.6	-0.4	-0.7	-0.3	-0.2	0.1	0.3	0.5	-0.1	0.5
Short access day 10 total locomotion	0.4	1.6	3.1	-1.2	-1.2	1.4	1.0	1.0	1.4	1.1	-1.5	-1.2	-1.8	0.7
Short access total locomotion	0.3	0.4	0.8	-0.4	-0.3	0.5	0.3	0.3	0.6	0.8	-0.8	-0.6	-0.9	0.9
One hour access (0.3 mA shock)	0.2	0.3	0.7	0.5	0.5	-0.7	-0.5	-0.3	-0.4	-0.3	0.5	0.7	0.8	0.5
Compulsive drug intake	1.1	1.6	6.4	-0.5	-0.5	0.4	0.6	1.1	1.0	1.5	-1.7	-1.3	-1.1	2.5
One hour access (shock baseline)	0.6	1.5	4.1	0.4	0.3	-0.5	-0.4	-0.9	-1.0	-1.1	1.8	2.0	1.6	-1.6
Social response proportion	0.8	1.0	2.4	-0.9	-0.9	1.0	0.9	0.6	1.0	0.9	-1.2	-1.5	-1.2	0.8
Social responses	0.5	0.6	2.2	-0.4	-0.4	0.4	0.3	0.3	0.6	0.3	-1.2	-1.5	-1.5	-0.0
Social time	4.1	6.4	8.9	-2.7	-2.7	2.8	2.7	3.0	2.7	2.7	-2.3	-1.3	-2.4	2.1
Soleus weight	5.2	15.4	20.9	-3.7	-3.8	3.8	3.8	3.9	4.0	3.8	-4.6	-4.1	-3.8	3.8
Bone: stiffness	0.3	0.5	1.6	0.5	0.4	-0.5	-0.3	-0.5	-0.7	-0.4	1.1	0.9	1.3	0.0
Tibialis anterior weight	0.8	2.7	3.8	1.7	1.6	-1.8	-1.6	-1.7	-1.7	-1.5	1.6	1.5	1.9	-1.5
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	-0.4	-0.3	0.3	0.3	0.4	0.0	0.4	0.3	0.4	0.3	0.1
Time to tail flick, vehicle, after self-admin	0.3	0.6	1.1	-1.1	-0.8	1.0	0.9	0.9	0.9	0.8	-0.5	-0.5	-0.3	0.0
Time to tail flick, test, before self-admin	0.3	0.3	1.0	0.0	-0.3	-0.1	-0.1	-0.1	-0.3	-0.5	1.0	1.0	0.9	-0.5
Time to tail flick, test, after self-admin	0.6	0.6	1.5	-0.7	-0.7	0.5	0.5	0.5	-0.0	-0.2	0.8	1.1	1.2	-1.2
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.6	0.4	0.6	-0.4	-0.5	-0.4	-0.3	-0.5	0.5	0.4	0.8	-0.4
Delta time to tail flick, test, before/after SA	0.3	0.4	1.0	0.6	1.0	-0.6	-0.7	-0.5	-0.8	-0.3	0.4	0.7	0.6	-0.2
Tibia length	2.7	7.4	11.7	-3.3	-3.3	3.1	3.4	2.7	2.8	2.5	-1.9	-2.5	-1.8	1.8
Ambulatory time before self-admin	0.1	0.4	0.8	-0.8	-0.9	0.8	0.8	0.6	0.6	0.6	-0.1	0.2	0.1	0.0
Ambulatory time after self-admin	0.6	0.9	1.7	-1.3	-1.3	1.2	1.2	0.7	1.0	0.5	-0.9	-0.6	-0.2	-0.9
Bone: tissue strength	0.1	0.1	0.2	-0.2	-0.2	0.2	0.4	0.2	0.1	0.3	0.2	0.3	0.5	0.0
Total heroin consumption	0.2	0.3	0.9	-0.7	-0.9	0.7	0.8	0.5	0.6	0.3	-0.4	-0.2	-0.1	-0.2
Bone: trabecular number	1.6	2.9	5.1	1.7	1.7	-1.8	-1.6	-1.5	-1.9	-1.2	2.0	1.9	2.2	-0.6
Bone: trabecular spacing	2.0	2.9	6.4	-1.7	-1.7	1.8	1.8	1.6	1.8	1.1	-1.5	-1.8	-2.5	0.6
Bone: trabecular thickness	1.1	1.6	3.6	1.2	1.2	-1.2	-1.1	-1.1	-1.4	-0.6	1.9	1.5	1.5	-0.2
Bone: trabecular tissue density	0.1	0.2	0.7	-0.2	-0.3	0.3	0.1	0.3	0.4	-0.4	-0.6	-0.3	-0.5	-0.8
Water consumed over 24 hours	0.1	0.2	0.3	-0.4	-0.4	0.4	0.3	0.5	0.5	0.5	-0.5	-0.6	-0.3	0.2
Number of responses in last shaping day	1.0	1.3	3.8	-0.5	-0.5	0.7	0.4	0.8	1.2	0.7	-1.8	-1.9	-1.9	0.6