Hub : Genes

LOC120097692

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	LOC120097692	0.07	0.04	5.3e-08	0.09	0.07	0.07	0.08	2.6e-08	2.6e-07	3.4e-07	1.0e-07
2	IC	gene expression	LOC120097692	0.16	0.08	1.6e-05	0.12	0.11	0.1	0.12	7.3e-06	2.2e-05	5.3e-05	1.2e-05
3	BLA	gene expression	LOC120097692	0.13	0.07	8.6e-07	0.09	0.1	0.11	0.11	1.2e-05	5.9e-06	1.5e-06	2.6e-06
4	Liver	gene expression	LOC120097692	0.03	0.02	7.7e-05	0.02	0.03	0.02	0.02	3.4e-03	1.1e-04	1.0e-03	1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.2	0.4	0.7	-0.7	-0.7	0.2	-0.8
Area under the delay curve	1.5	1.7	2.1	-1.5	-1.4	-1.0	1.3
BMI with tail	5.7	19.7	26.9	-5.2	-5.1	-4.3	2.7
BMI without tail	4.4	13.4	17.2	-4.1	-4.1	-3.8	2.3
Body weight	4.0	17.6	26.6	-5.2	-5.1	-3.7	2.0
Weight adjusted by age	6.1	9.3	12.0	-3.5	-3.3	-3.0	2.2
Bone surface	0.1	0.2	0.3	-0.6	-0.5	-0.2	-0.6
Bone volume	0.8	1.5	2.5	-1.6	-1.6	-1.0	0.3
Breakpoint value in progressive ratio session	0.8	0.9	1.3	-1.0	-1.1	-1.1	0.4
Number of licking bursts	0.4	0.6	1.7	0.1	0.1	0.8	-1.3
Context. condit. distance diff. score	1.1	1.4	2.0	1.4	1.3	1.0	-0.9
Locomotion velocity, session 1	0.3	0.3	0.6	0.8	0.6	0.3	-0.2
Locomotion distance, session 1	0.1	0.2	0.3	0.6	0.4	-0.3	0.2
Locomotion velocity, session 2	0.4	0.4	0.9	0.9	0.9	-0.1	0.1
Locomotion distance, session 2	0.1	0.1	0.4	0.0	-0.1	-0.6	0.4
Locomotion velocity, session 3	0.2	0.3	0.6	0.8	0.6	0.2	-0.0
Locomotion distance, session 3	0.4	0.4	0.9	0.9	0.9	0.2	0.1
Stereotopy head waving bouts, day 3	0.0	0.0	0.0	0.1	0.1	0.1	0.1
Stereotopy head waving duration, day 3	0.0	0.0	0.0	-0.1	-0.1	0.2	-0.2
Locomotion velocity, session 7	0.7	0.8	1.1	-1.0	-1.1	-1.0	0.5
Locomotion distance, session 7	0.1	0.1	0.2	-0.3	-0.4	-0.4	0.3
Stereotopy head waving bouts, day 7	0.1	0.2	0.2	-0.3	-0.3	-0.5	0.4
Stereotopy head waving duration, day 7	0.9	1.1	1.4	-1.2	-1.2	-1.0	0.9
Locomotion velocity, session 8	3.9	4.7	5.4	2.3	2.2	2.1	-2.0
Locomotion distance, session 8	2.6	3.8	5.3	2.3	2.1	1.6	-1.6
Degree of sensitization distance	0.3	0.4	0.7	-0.8	-0.9	-0.1	-0.1
Degree of sensitization stereotypy	0.2	0.2	0.3	-0.5	-0.6	-0.5	0.3
Conditioned locomotion	0.2	0.2	0.4	-0.3	-0.4	-0.5	0.6
Cocaine response after cond. corrected	0.5	0.6	1.1	1.0	1.0	-0.1	0.5
Cocaine response after cond. not corrected	0.6	0.7	1.5	1.2	1.2	0.2	0.1
Cocaine response before conditioning	0.3	0.4	0.9	0.3	0.2	0.8	-0.9
Saline control response	0.2	0.3	0.6	-0.1	-0.3	-0.7	0.8
Bone: connectivity density	0.4	0.5	1.4	0.3	0.4	0.8	-1.2
Bone: cortical apparent density	0.4	0.6	1.0	1.0	1.0	-0.1	0.5
Bone: cortical area	5.3	8.2	12.0	-3.4	-3.5	-2.8	1.2
Bone: cortical porosity	0.7	0.8	1.3	0.9	0.7	1.2	-0.7
Bone: cortical porosity	0.7	0.8	1.6	0.7	0.5	1.3	-0.9
Bone: cortical thickness	2.2	3.6	5.0	-2.2	-2.2	-2.0	0.8
Bone: cortical thickness	1.6	1.9	2.2	-1.4	-1.4	-1.5	1.1
Bone: cortical tissue density	0.6	0.8	1.5	1.2	1.2	0.1	0.4
Condit. Reinf. active minus inactive responses	3.7	4.2	4.7	2.1	2.1	2.2	-1.8
Condit. Reinf. active-inactive response ratio	2.0	2.1	2.7	1.4	1.4	1.7	-1.3
Condit. Reinf. active responses	2.2	2.8	3.2	1.5	1.5	1.8	-1.8
Condit. Reinf. inactive responses	0.5	0.6	1.3	0.4	0.5	0.8	-1.1
Incentive salience index mean	4.0	4.9	5.7	2.4	2.3	2.3	-1.8
Condit. Reinf. lever presses	1.9	2.7	3.2	1.8	1.8	1.7	-1.2
Condit. Reinf. active minus inactive responses	0.4	0.5	1.1	-1.1	-0.9	-0.2	-0.3
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.9	-0.9	-0.9	-0.3	-0.0
Condit. Reinf. active responses	0.8	1.2	2.4	-1.6	-1.4	-0.5	-0.1
Condit. Reinf. inactive responses	0.2	0.3	0.6	-0.8	-0.7	-0.1	-0.1
Condit. Reinf. lever presses	0.5	0.7	1.2	-1.0	-1.1	-0.7	0.2
Condit. Reinf. lever reinforcers received	0.6	0.8	1.6	-1.3	-1.2	-0.4	-0.3
Conditioned reinforcement - actives	0.2	0.3	0.8	-0.3	-0.3	-0.5	0.9
Conditioned reinforcement - inactives	0.3	0.4	0.7	-0.7	-0.8	-0.5	0.5
Conditioned locomotion	0.1	0.2	0.5	0.0	0.1	-0.4	0.7
Patch foraging indifference point 0 sec	2.8	5.3	8.2	-2.9	-2.4	-2.4	1.3
Patch foraging indifference point AUC	1.2	1.8	2.6	-1.5	-1.6	-1.3	0.8
Delay disc. indifference point, 0s delay	1.5	1.6	2.0	-1.2	-1.3	-1.4	1.1
Delay disc. indifference point, 16s delay	0.3	0.4	0.5	-0.7	-0.7	-0.4	0.6
Delay disc. indifference point, 2s delay	0.4	0.4	1.2	-0.2	-0.2	-0.6	1.1
Delay disc. indifference point, 24s delay	0.2	0.3	0.5	-0.7	-0.6	0.3	0.3
Delay disc. indifference point, 4s delay	0.3	0.3	0.6	-0.5	-0.4	-0.4	0.7
Delay disc. indifference point, 8s delay	6.0	7.0	8.9	-3.0	-2.9	-2.5	2.1
Indifference point function ln k	0.5	0.8	1.1	0.9	1.1	0.9	-0.7
Indifference point function log k	0.5	0.8	1.1	0.9	1.1	0.9	-0.7
Patch foraging total patch changes 0 sec	3.2	6.1	9.2	-3.0	-2.6	-2.5	1.3
Patch foraging total patch changes 12 sec	2.6	3.4	4.9	-2.2	-2.1	-1.8	0.9
Patch foraging total patch changes 18 sec	4.6	7.1	10.1	-3.2	-3.2	-2.5	1.4
Patch foraging total patch changes 24 sec	3.9	6.8	9.7	-3.1	-3.0	-2.6	1.4
Patch foraging total patch changes 6 sec	5.5	8.3	12.1	-3.5	-3.3	-2.8	1.5
Patch foraging time to switch 0 sec	0.2	0.4	0.8	0.9	0.8	0.6	-0.1
Patch foraging water rate 0 sec	0.3	0.6	1.2	-1.1	-0.9	-0.8	0.3
Patch foraging water rate 12 sec	0.5	1.0	1.9	-1.3	-1.4	-0.5	-0.1
Patch foraging water rate 18 sec	0.4	0.7	1.2	-0.8	-0.6	-1.1	0.7
Patch foraging water rate 24 sec	1.2	1.7	2.5	-1.2	-1.1	-1.6	1.2
Patch foraging water rate 6 sec	1.3	1.9	2.6	-1.4	-1.3	-1.6	1.1
Seeking ratio, delayed vs. immediate footshock	2.3	2.8	4.2	2.1	2.0	1.4	-1.0
Distance traveled before self-admin	0.5	0.6	1.1	0.7	0.6	-0.8	1.1
Distance traveled after self-admin	0.4	0.5	0.9	0.7	0.7	-0.6	1.0
Extensor digitorum longus weight	0.4	1.5	2.4	-1.5	-1.6	-0.8	0.8
Bone: elastic displacement	0.5	0.6	0.9	-0.6	-0.8	-0.7	1.0
Bone: elastic work	1.1	1.5	2.3	-0.9	-1.0	-1.4	1.5
Bone: endosteal estimation	0.7	1.6	2.5	-1.6	-1.6	-1.1	0.5
Bone: endosteal perimeter	4.8	10.2	12.8	-3.6	-3.5	-3.3	2.2
Epididymis fat weight	4.5	15.5	27.9	-5.0	-5.3	-2.9	1.2
Delta time in closed arm before/after self-admin	0.5	0.5	0.8	0.9	0.9	0.6	-0.2
Delta time in open arm before/after self-admin	1.0	1.0	2.4	-1.6	-1.2	-0.4	-0.2
Diff in mean of infusions in LGA sessions	0.4	0.5	0.8	0.8	0.9	0.4	-0.7
Delay discount exponential model param	1.5	1.6	2.0	1.4	1.4	1.0	-1.3
Extinction: sum of active levers before priming	0.0	0.0	0.0	0.1	0.0	0.0	-0.1
Active lever presses in extinction session 6	0.0	0.0	0.0	-0.0	-0.2	-0.1	0.1
Bone: final force	1.7	2.8	4.0	-1.9	-2.0	-1.7	0.8
Bone: final moment	1.6	2.6	3.9	-1.8	-2.0	-1.6	0.7
Food consumed during 24 hour testing period	1.6	2.2	2.7	1.6	1.7	1.4	-1.3
Glucose	1.6	2.6	3.3	-1.8	-1.8	-1.6	1.2
Heart weight	0.9	1.3	2.3	-1.5	-1.5	-0.8	0.1
Delay discount hyperbolic model param	1.3	1.5	1.8	1.3	1.3	0.9	-1.3
Intermittent access intake day 1-15 change	1.7	3.6	4.1	-1.8	-1.8	-2.0	2.0
Intermittent access intake escalation	1.3	2.7	2.8	-1.6	-1.6	-1.6	1.7
Intermittent access intake escalation 2	1.6	1.9	2.1	-1.3	-1.4	-1.4	1.4
Intermitt. access day 1 inactive lever presses	0.5	1.9	3.7	-1.9	-1.9	-0.5	0.3
Intermitt. access day 15 inactive lever presses	0.7	1.4	2.3	-1.5	-1.5	-0.7	0.7
Intermitt. access escalation Index	0.5	0.7	1.0	0.8	0.9	1.0	-0.5
Intermittent access day 1 total infusions	0.2	0.4	0.6	-0.5	-0.6	-0.5	0.8
Intermittent access day 15 total infusions	1.4	2.1	2.9	-1.3	-1.4	-1.3	1.7
Intermittent access terminal intake (last 3 days)	1.1	1.5	2.1	-1.2	-1.2	-1.0	1.4
Intermittent access total infusions	1.9	2.2	2.5	-1.5	-1.6	-1.2	1.6
Intermittent access day 1 locomotion	1.8	2.3	3.9	-1.2	-1.3	-1.5	2.0
Intermittent access day 15 total locomotion	3.6	6.6	8.2	-2.9	-2.8	-2.4	2.1
Intermittent access total locomotion	3.4	4.1	5.6	-1.8	-1.8	-2.0	2.4
Intermittent access standard deviation	2.5	5.3	6.3	-2.4	-2.5	-2.3	1.9
Left kidney weight	1.1	5.1	7.2	-2.4	-2.3	-2.7	1.5
Right kidney weight	2.7	12.1	17.6	-3.5	-3.4	-4.2	2.7
Cocaine induced anxiety	2.5	3.6	4.9	2.1	2.1	2.2	-0.9
Post-drug Anxiety	1.0	1.1	1.9	0.8	0.8	1.4	-1.1
Baseline Anxiety	1.0	1.1	1.8	-1.3	-1.3	-0.9	-0.3
Tail length	0.1	0.2	0.3	-0.6	-0.6	-0.4	0.2
Length with tail	0.2	0.8	1.6	-1.3	-1.2	-0.5	-0.1
Length without tail	0.7	2.2	4.4	-2.1	-1.9	-0.8	-0.2
Times rat made contact with spout	0.0	0.0	0.1	0.1	0.1	-0.2	0.1
Lifetime Intake	1.7	2.1	2.4	-1.5	-1.5	-1.3	1.4
Liver weight, left	3.7	6.1	8.5	-2.9	-2.8	-2.4	1.4
Liver weight, right	2.4	4.1	5.5	-2.1	-1.9	-2.3	1.8
Locomotor activity	0.9	1.5	1.8	-1.4	-1.0	-1.3	1.1
Locomotor testing distance	1.5	2.7	4.1	-1.5	-1.2	-2.0	1.7
Locomotor testing rearing	1.7	3.5	4.7	-1.7	-1.5	-2.2	2.0
Locomotion in novel chamber	1.1	1.5	2.6	1.5	1.6	0.9	-0.3
Locomotion in novel chamber post-restriction	1.3	2.1	3.5	1.7	1.9	1.3	-0.3
Fecal boli incidents, locomotor time 1	1.3	2.0	2.7	-1.6	-1.4	-1.6	0.8
Change in fecal boli incidents, locomotor task	6.3	6.2	7.2	2.7	2.6	2.7	-2.0
Time >=10cm from walls, locomotor time 1	3.9	4.2	5.4	2.0	2.0	2.3	-1.8
Bouts of movement, locomotor time 1	2.8	3.2	4.2	-2.0	-2.0	-1.7	1.3
Total resting periods, locomotor time 1	2.3	2.6	3.1	-1.8	-1.8	-1.6	1.3
Rest time, locomotor task time 1	1.4	1.8	2.1	-1.4	-1.3	-1.4	1.2
Distance moved, locomotor task time 1	0.1	0.2	0.4	0.6	0.4	0.5	-0.2
Vertical activity count, locomotor time 1	1.0	2.3	3.6	1.9	1.6	1.6	-0.7
Time >=10cm from walls, locomotor time 2	0.5	0.8	1.4	0.8	0.7	0.9	-1.2
Bouts of movement, locomotor time 2	0.1	0.1	0.2	0.3	0.2	-0.2	0.4
Total resting periods, locomotor time 2	0.2	0.3	0.7	-0.3	-0.3	-0.7	0.8
Rest time, locomotor task time 2	1.6	2.0	2.4	-1.5	-1.2	-1.5	1.4
Distance moved, locomotor task time 2	0.0	0.0	0.1	-0.0	-0.3	0.0	-0.3
Vertical activity count, locomotor time 2	0.2	0.3	0.7	0.5	0.1	0.8	-0.5
Light reinforcement 1	0.8	1.9	2.6	1.5	1.6	1.5	-0.8
Light reinforcement 2	1.8	2.8	4.1	1.9	2.0	1.5	-1.1
Bone: marrow area	0.7	1.5	2.5	-1.6	-1.6	-1.0	0.5
Bone: maximum diameter	4.5	8.5	12.6	-3.6	-3.6	-2.6	1.4
Bone: maximum force	0.6	1.2	1.7	-1.3	-1.3	-1.1	0.2
Bone: maximum moment	0.6	1.0	1.6	-1.2	-1.3	-0.9	0.1
Mean time between licks in bursts	0.7	1.6	2.5	1.0	0.9	1.6	-1.5
Mean num. licks in bursts	0.6	0.9	2.3	-0.1	-0.2	-1.1	1.5
Cd content in liver	0.5	0.6	1.2	1.0	1.1	0.2	-0.1
Co content in liver	0.0	0.0	0.1	0.3	0.0	-0.2	0.1
Cu content in liver	0.0	0.0	0.1	0.0	-0.1	-0.2	0.4
Fe content in liver	0.5	0.6	1.3	-0.0	-0.2	1.0	-1.1
K content in liver	0.3	0.3	0.6	-0.3	-0.4	-0.6	0.7
Mg content in liver	1.3	1.3	2.3	-0.8	-1.0	-1.2	1.5
Mn content in liver	0.1	0.1	0.2	0.1	-0.1	-0.2	0.5
Na content in liver	0.3	0.3	0.7	-0.4	-0.2	-0.4	0.9
Rb content in liver	0.2	0.2	0.6	0.5	0.2	0.8	-0.2
Se content in liver	0.4	0.4	0.5	0.7	0.5	0.7	-0.6
Sr content in liver	0.7	0.6	1.3	1.0	1.2	0.5	0.2
Zn content in liver	0.3	0.4	1.2	0.1	-0.1	-0.4	1.1
Bone: minimum diameter	2.2	3.9	6.0	-2.5	-2.4	-1.8	0.7
Time in familiar zone, hab. session 1	0.2	0.2	0.5	-0.0	0.1	-0.4	0.7
Time in novel zone, hab. session 1	0.3	0.3	0.5	-0.6	-0.7	0.2	-0.6
Total zone transitions, hab. session 1	1.2	1.7	2.7	-1.1	-1.1	-1.6	1.3
Total locomotion distance, hab. session 1	0.9	1.2	1.6	1.1	0.9	1.2	-1.3
Locomotion velocity, hab. session 1	1.1	1.6	1.7	1.3	1.2	1.2	-1.3
Time in familiar zone, hab. session 2	0.3	0.3	0.5	-0.7	-0.6	0.3	-0.6
Time in novel zone, hab. session 2	0.2	0.2	0.3	0.5	0.4	-0.4	0.6
Total zone transitions, hab. session 2	1.5	2.0	2.7	-1.2	-1.3	-1.6	1.4
Total locomotion distance, hab. session 2	0.1	0.1	0.1	0.4	0.4	0.2	-0.2
Locomotion velocity, hab. session 2	0.0	0.0	0.1	0.3	0.2	0.0	-0.0
Novel to familiar place preference ratio	0.9	1.0	1.8	0.7	0.5	1.2	-1.3
Novelty place preference	0.6	0.7	1.2	0.5	0.4	1.0	-1.1
Time in novel zone, NPP test	0.5	0.5	1.3	0.2	0.1	0.9	-1.1
Total zone transitions, NPP test	0.4	0.5	1.0	-0.6	-0.5	-1.0	0.7
Total locomotion distance, NPP test	0.7	1.0	1.1	1.0	1.1	0.8	-1.1
Locomotion velocity, NPP test	1.0	1.5	2.0	1.4	1.4	0.9	-1.1
Intraocular pressure	1.4	2.1	3.4	-1.8	-1.8	-1.2	0.4
Delta distance traveled before/after self-admin	0.2	0.2	0.5	-0.4	-0.3	-0.1	0.7
Delta ambulatory time before/after self-admin	0.1	0.1	0.2	-0.5	-0.3	0.0	0.4
Parametrial fat weight	9.5	22.4	33.7	-5.8	-5.8	-4.2	2.2
Pavlov. Cond. lever latency	0.3	0.3	0.5	-0.7	-0.7	-0.5	0.2
Pavlov. Cond. magazine entry latency	0.7	0.8	1.3	0.9	0.9	1.1	-0.6
Pavlov. Cond. change in total contacts	0.3	0.3	0.4	0.6	0.6	0.6	-0.2
Pavlov. Cond. index score	0.1	0.1	0.2	0.4	0.5	0.4	-0.1
Pavlov. Cond. latency score	0.0	0.1	0.1	0.3	0.3	0.2	-0.0
Pavlov. Cond. lever contacts	0.1	0.1	0.2	0.3	0.4	0.2	-0.0
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	-0.1	-0.1	-0.2	-0.2
Pavlov. Cond. intertrial magazine entries	0.7	0.8	0.8	0.9	0.9	0.8	-0.9
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.3	0.5	0.6	0.6	0.7	-0.3
Pavlov. Cond. response bias	0.4	0.5	0.7	0.8	0.8	0.8	-0.3
Pavlov. Cond. lever latency	0.2	0.2	0.4	0.7	0.7	0.1	0.3
Pavlov. Cond. magazine entry latency	0.3	0.3	0.7	-0.7	-0.8	-0.4	0.2
Pavlov. Cond. change in total contacts	0.5	0.7	1.4	-1.1	-1.2	-0.6	0.1
Pavlov. Cond. index score	0.4	0.6	1.1	-1.0	-1.1	-0.5	0.1
Pavlov. Cond. latency score	0.5	0.7	1.3	-1.1	-1.1	-0.6	0.1
Pavlov. Cond. lever contacts	0.2	0.2	0.4	-0.7	-0.7	-0.3	-0.1
Pavlov. Cond. magazine entry number	0.3	0.4	0.7	0.8	0.9	0.5	-0.2
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.3	-0.6	-0.4	-0.3	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.7	1.2	-1.0	-1.1	-0.6	0.2
Pavlov. Cond. response bias	0.2	0.3	0.5	-0.7	-0.7	-0.2	-0.3
Time in closed arm before self-admin	0.1	0.2	0.5	-0.3	-0.2	-0.1	0.7
Time in closed arm after self-admin	0.3	0.3	0.3	0.6	0.5	0.4	0.6
Time in open arm before self-admin	3.5	3.8	5.2	2.3	2.1	1.6	-1.7
Time in open arm after self-admin	0.1	0.2	0.6	-0.2	0.1	0.1	-0.8
Bone: periosteal estimation	2.7	5.7	8.6	-2.9	-2.9	-2.2	1.0
Bone: periosteal perimeter	10.3	17.7	22.9	-4.8	-4.7	-4.2	2.7
Bone: post-yield work	2.1	3.1	4.4	1.4	1.4	2.0	-2.1
Progressive ratio test 1 active lever presses	1.8	2.2	2.9	-1.4	-1.4	-1.4	1.7
Progressive ratio test 1 breakpoint	1.7	2.1	2.8	-1.3	-1.4	-1.4	1.7
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.4	-0.5	-0.6	-0.2	0.5
Progressive ratio test 2 active lever presses	3.3	3.9	4.7	-2.1	-2.2	-1.6	1.9
Progressive ratio test 2 breakpoint	3.3	3.8	4.7	-2.1	-2.2	-1.6	1.9
Progressive ratio test 2 inactive lever presses	1.0	1.7	2.9	-1.6	-1.7	-0.9	0.6
Incentive Sensitization - Responses	1.5	2.1	2.9	-1.7	-1.7	-1.1	1.3
Incentive Sensitization - Breakpoint	1.4	1.8	2.6	-1.6	-1.6	-0.9	1.2
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.2	0.2	0.1	-0.1
Progressive ratio	0.3	0.5	0.6	0.8	0.8	0.6	-0.8
Food seeking constrained by brief footshock	0.6	0.8	1.9	0.7	0.6	1.4	-0.6
Seeking ratio, punishment vs. effort	0.4	0.5	1.0	-0.7	-0.8	-0.3	1.0
Retroperitoneal fat weight	5.6	24.0	40.7	-6.2	-6.4	-3.7	1.6
Reaction time number correct	1.4	2.7	3.6	-1.7	-1.9	-1.5	1.4
Reaction time mean minus median	0.7	1.7	1.9	-1.3	-1.3	-1.2	1.4
Reaction time mean minus median AUC	1.4	3.6	5.3	-1.6	-1.6	-1.9	2.3
Reaction time num false alarms	0.3	0.4	0.6	0.6	0.8	0.6	-0.4
Reaction time num false alarms AUC	0.1	0.1	0.3	0.4	0.6	0.2	-0.0
Reaction time trials correct on left	1.4	2.7	3.6	-1.7	-1.9	-1.5	1.4
Reaction time trials on left	1.6	2.9	3.9	-1.8	-2.0	-1.5	1.5
Reaction time mean	0.9	1.4	2.5	-0.9	-1.1	-1.0	1.6
Reaction time mean AUC	0.8	1.3	2.7	-0.8	-1.0	-1.0	1.7
Median of all reaction times	0.7	1.0	2.3	-0.6	-0.8	-0.9	1.5
Reaction time omissions	0.9	1.2	2.1	-1.3	-1.4	-0.6	1.0
Reaction time false alarm rate	1.5	2.0	2.8	1.5	1.7	1.3	-1.1
Reaction time premature initiation rate	0.2	0.3	0.9	-0.2	-0.1	-0.9	0.6
Reaction time premature initiations	1.4	2.5	3.8	-1.3	-1.4	-1.9	1.6
Std. dev. reaction times	1.9	3.6	4.1	-1.9	-2.0	-1.8	1.8
Reaction time trials completed	1.6	2.9	3.9	-1.8	-2.0	-1.5	1.5
Reaction time trials AUC	1.5	2.9	3.9	-1.8	-2.0	-1.6	1.5
Run reversals in cocaine runway, females	0.6	0.6	0.9	-0.9	-1.0	-0.4	0.6
Run reversals in cocaine runway, males	0.1	0.1	0.4	0.6	0.4	0.0	0.2
Latency to leave start box in cocaine runway	0.1	0.1	0.2	-0.2	-0.2	-0.4	0.5
Latency to leave start box in cocaine runway, F	0.1	0.2	0.4	0.5	0.6	0.2	-0.2
Latency to leave start box in cocaine runway, M	1.5	1.4	1.9	-1.2	-1.4	-1.0	1.1
Std. dev. time between licks in bursts	1.7	2.3	3.4	1.3	1.3	1.6	-1.8
Total sessions with >9 infusions	1.9	2.3	2.6	-1.6	-1.6	-1.6	1.2
Short access day 1 total inactive lever presses	1.2	1.6	2.4	1.1	1.0	1.4	-1.5
Short access day 10 total inactive lever presses	0.3	0.6	0.8	-0.8	-0.9	-0.8	0.6
Short access day 1 total infusions	0.2	0.3	0.4	-0.4	-0.4	-0.7	0.6
Short access day 10 total infusions	0.3	0.4	0.9	-0.2	-0.2	-0.8	1.0
Short access total infusions	0.4	0.5	0.7	-0.6	-0.6	-0.8	0.8
Short access day 1 locomotion	1.8	2.2	3.4	-1.3	-1.3	-1.8	1.5
Short access day 10 total locomotion	2.1	3.9	4.3	-1.9	-1.9	-2.1	2.1
Short access total locomotion	3.6	4.4	5.6	-1.9	-1.8	-2.4	2.2
One hour access (0.3 mA shock)	0.8	0.9	1.7	-1.3	-1.3	-0.3	0.6
Compulsive drug intake	0.9	1.0	1.7	0.8	0.8	1.3	-1.1
One hour access (shock baseline)	1.7	2.7	2.9	-1.7	-1.7	-1.5	1.6
Social response proportion	1.0	1.1	1.9	-0.7	-0.8	-1.4	1.2
Social responses	4.5	5.8	7.3	-2.7	-2.7	-2.5	1.5
Social time	2.4	3.3	4.3	-1.6	-1.6	-2.0	2.1
Soleus weight	4.6	13.4	15.6	-3.4	-3.3	-3.9	3.9
Bone: stiffness	0.6	1.0	1.4	-1.2	-1.1	-1.1	0.1
Tibialis anterior weight	0.4	1.4	2.0	-1.3	-1.4	-0.9	1.1
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.6	-0.8	-0.5	-0.0	-0.2
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.1	0.2	-0.2	-0.2	-0.1
Time to tail flick, test, before self-admin	1.2	1.2	2.5	-0.3	-0.3	-1.5	1.6
Time to tail flick, test, after self-admin	0.5	0.5	1.1	-1.0	-1.0	-0.2	0.1
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.5	-0.3	-0.7	-0.7	0.2
Delta time to tail flick, test, before/after SA	0.4	0.4	0.6	-0.8	-0.8	0.2	-0.4
Tibia length	0.9	2.5	3.5	-1.5	-1.7	-1.9	1.1
Ambulatory time before self-admin	0.4	0.5	1.1	0.1	-0.0	-1.0	1.1
Ambulatory time after self-admin	0.5	0.6	1.4	0.0	0.1	-0.9	1.2
Bone: tissue strength	0.0	0.0	0.1	0.1	0.2	0.2	-0.3
Total heroin consumption	1.3	1.6	2.0	-1.4	-1.4	-1.4	0.6
Bone: trabecular number	0.3	0.5	1.3	-0.3	-0.2	0.6	-1.2
Bone: trabecular spacing	0.0	0.0	0.0	0.1	0.2	0.1	-0.0
Bone: trabecular thickness	3.3	4.2	6.4	-2.5	-2.5	-1.8	1.0
Bone: trabecular tissue density	0.8	1.1	2.0	-0.6	-0.8	-1.2	1.4
Water consumed over 24 hours	0.1	0.2	0.4	-0.2	-0.2	-0.6	0.5
Number of responses in last shaping day	1.2	1.3	2.3	-0.8	-0.7	-1.5	1.3