LOC120097534

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression LOC120097534 0.16 0.1 8.3e-04 0.07 0.07 0.1 0.08 7.8e-03 5.5e-03 1.6e-03 3.6e-03
2 Brain alternative TSS XR_005495042.1 0.05 0.03 1.0e-05 0.04 0.05 0.03 0.04 1.3e-04 3.6e-05 1.4e-03 1.2e-04
3 Brain isoform ratio XR_005495042.1 0.04 0.03 1.3e-04 0.05 0.04 0.02 0.04 4.3e-05 2.8e-04 8.2e-03 2.4e-04
4 Brain alternative TSS XR_005495041.1 0.02 0.02 3.6e-03 0 0.01 0 0 1.3e-01 7.1e-02 3.0e-01 3.6e-01
5 Brain gene expression LOC120097534 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 2.5e-03 4.4e-03 2.4e-02 8.4e-03
6 Adipose alternative TSS XR_005495040.1 0.09 0.06 5.7e-06 0.04 0.04 0.03 0.04 4.5e-05 8.7e-05 2.2e-04 4.0e-05
7 Adipose alternative TSS XR_005495042.1 0.07 0.04 2.6e-08 0.06 0.05 0.04 0.06 3.8e-07 2.0e-06 6.0e-05 5.3e-07
8 Adipose mRNA stability LOC120097534 0.17 0.08 0.0e+00 0.14 0.13 0.13 0.13 8.7e-16 5.9e-14 1.1e-14 1.3e-14
9 Adipose isoform ratio XR_005495042.1 0.05 0.03 9.6e-05 0.03 0.02 0.02 0.03 7.2e-04 1.1e-03 9.2e-04 6.8e-04
10 Adipose gene expression LOC120097534 0.63 0.16 0.0e+00 0.3 0.32 0.31 0.31 3.5e-34 1.2e-36 1.7e-34 7.0e-35

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.71.22.91.7-1.21.11.11.0-1.0-1.0-1.00.9-1.1
Area under the delay curve1.41.41.9-0.61.2-1.3-1.3-1.41.31.31.3-1.30.8
BMI with tail1.03.45.92.4-1.91.71.81.5-1.8-1.9-1.91.8-1.5
BMI without tail1.83.85.52.3-1.91.91.91.6-1.9-2.0-2.01.9-1.9
Body weight0.62.63.21.4-1.61.81.61.6-1.7-1.7-1.71.7-1.1
Weight adjusted by age0.50.52.21.5-0.80.70.70.7-0.5-0.5-0.50.5-0.3
Bone surface1.73.04.42.1-1.71.71.71.6-1.7-1.7-1.71.6-1.8
Bone volume1.83.14.12.0-1.81.81.71.7-1.8-1.7-1.71.7-1.7
Breakpoint value in progressive ratio session0.91.01.7-1.31.1-1.2-1.0-1.20.70.70.7-0.70.7
Number of licking bursts2.22.63.4-0.81.5-1.8-1.7-1.71.71.71.7-1.81.4
Context. condit. distance diff. score0.20.30.40.4-0.50.40.50.4-0.7-0.6-0.60.6-0.3
Locomotion velocity, session 15.66.07.1-1.62.4-2.7-2.6-2.72.62.62.6-2.72.0
Locomotion distance, session 11.82.32.7-1.21.5-1.5-1.6-1.51.61.71.7-1.61.4
Locomotion velocity, session 20.81.01.3-0.71.0-1.1-1.1-1.11.01.01.0-1.10.3
Locomotion distance, session 20.81.11.5-0.40.9-1.0-1.0-1.01.21.21.2-1.20.9
Locomotion velocity, session 30.10.10.6-0.70.3-0.1-0.2-0.10.20.20.2-0.20.4
Locomotion distance, session 30.20.21.2-1.1-0.00.40.20.4-0.4-0.4-0.40.4-0.1
Stereotopy head waving bouts, day 30.30.30.5-0.30.6-0.6-0.5-0.60.50.50.5-0.60.7
Stereotopy head waving duration, day 30.40.50.7-0.10.6-0.8-0.6-0.80.70.70.7-0.70.8
Locomotion velocity, session 70.60.60.80.6-0.80.90.80.9-0.7-0.8-0.80.8-0.7
Locomotion distance, session 70.81.01.30.8-1.01.21.01.2-0.9-1.0-1.00.9-1.0
Stereotopy head waving bouts, day 72.93.34.3-1.82.0-2.1-1.9-2.11.51.61.6-1.61.9
Stereotopy head waving duration, day 70.80.91.3-1.11.1-1.1-1.0-1.10.70.80.8-0.71.1
Locomotion velocity, session 80.00.00.1-0.20.3-0.3-0.3-0.30.00.10.1-0.20.2
Locomotion distance, session 80.10.10.20.20.2-0.4-0.3-0.40.30.30.3-0.30.4
Degree of sensitization distance0.20.21.01.0-0.0-0.3-0.2-0.30.40.30.3-0.40.0
Degree of sensitization stereotypy2.42.73.3-1.71.8-1.8-1.7-1.81.31.41.4-1.41.8
Conditioned locomotion1.92.22.71.2-1.51.31.51.4-1.6-1.6-1.61.6-1.1
Cocaine response after cond. corrected0.10.10.20.00.3-0.4-0.3-0.40.40.40.4-0.40.3
Cocaine response after cond. not corrected0.30.40.5-0.60.6-0.6-0.6-0.60.70.60.6-0.60.4
Cocaine response before conditioning1.01.22.4-1.51.1-0.9-1.1-0.91.21.11.1-1.00.7
Saline control response2.43.14.4-2.11.9-1.8-1.8-1.71.51.61.6-1.61.9
Bone: connectivity density2.33.66.82.6-2.01.71.81.7-1.7-1.7-1.71.7-2.1
Bone: cortical apparent density2.22.93.4-1.01.6-1.7-1.7-1.71.81.91.9-1.81.8
Bone: cortical area1.11.62.30.4-1.11.51.31.4-1.5-1.4-1.41.4-0.8
Bone: cortical porosity0.40.40.60.70.4-0.6-0.5-0.60.80.70.7-0.70.5
Bone: cortical porosity0.10.10.40.70.1-0.2-0.2-0.30.40.40.4-0.40.3
Bone: cortical thickness0.71.23.4-1.81.2-0.9-1.0-0.90.80.80.8-0.81.5
Bone: cortical thickness2.73.13.8-1.91.9-1.9-1.8-1.91.61.61.6-1.61.7
Bone: cortical tissue density2.12.83.4-0.81.6-1.7-1.7-1.71.81.81.8-1.81.7
Condit. Reinf. active minus inactive responses0.60.70.9-0.90.8-0.6-0.8-0.60.90.90.9-1.00.9
Condit. Reinf. active-inactive response ratio0.20.20.3-0.50.4-0.2-0.4-0.20.50.50.5-0.50.4
Condit. Reinf. active responses0.40.50.7-0.70.6-0.4-0.6-0.40.80.70.7-0.80.7
Condit. Reinf. inactive responses0.30.40.5-0.40.5-0.5-0.6-0.50.70.70.7-0.70.6
Incentive salience index mean0.50.61.5-1.20.9-0.6-0.8-0.60.80.70.7-0.80.7
Condit. Reinf. lever presses0.40.51.3-1.20.8-0.7-0.7-0.70.60.60.6-0.60.4
Condit. Reinf. active minus inactive responses2.53.03.31.8-1.81.71.81.8-1.7-1.8-1.81.7-1.6
Condit. Reinf. active-inactive response ratio1.41.52.31.5-1.31.11.21.1-1.1-1.2-1.21.2-1.2
Condit. Reinf. active responses1.62.32.90.7-1.41.51.51.5-1.7-1.7-1.71.6-1.4
Condit. Reinf. inactive responses0.20.31.8-1.30.10.10.20.2-0.6-0.5-0.50.5-0.0
Condit. Reinf. lever presses0.10.21.2-1.10.4-0.3-0.4-0.30.20.10.1-0.2-0.1
Condit. Reinf. lever reinforcers received0.81.11.50.3-1.01.01.11.1-1.2-1.2-1.21.2-1.0
Conditioned reinforcement - actives0.50.51.2-0.60.6-0.3-0.5-0.30.70.90.9-0.71.1
Conditioned reinforcement - inactives0.40.50.9-0.90.7-0.9-0.7-0.80.40.50.5-0.50.6
Conditioned locomotion1.21.52.2-1.21.1-0.8-1.1-0.61.31.51.5-1.31.4
Patch foraging indifference point 0 sec0.10.20.8-0.90.6-0.2-0.5-0.40.30.40.4-0.30.3
Patch foraging indifference point AUC4.85.67.0-2.72.6-2.6-2.5-2.32.12.12.1-2.32.1
Delay disc. indifference point, 0s delay0.70.72.01.4-0.90.70.80.6-0.7-0.7-0.70.7-0.9
Delay disc. indifference point, 16s delay1.11.11.6-0.81.1-1.2-1.2-1.31.11.11.1-1.10.7
Delay disc. indifference point, 2s delay0.10.10.50.7-0.1-0.2-0.2-0.30.30.30.3-0.3-0.6
Delay disc. indifference point, 24s delay4.84.65.0-1.92.2-2.1-2.2-2.12.22.22.2-2.22.1
Delay disc. indifference point, 4s delay0.90.91.2-0.40.9-1.0-1.0-1.11.01.11.1-1.00.8
Delay disc. indifference point, 8s delay3.94.14.7-1.52.0-2.1-2.1-2.22.12.22.2-2.21.5
Indifference point function ln k4.05.66.92.6-2.62.52.52.4-2.2-2.2-2.22.3-2.1
Indifference point function log k4.05.66.92.6-2.62.52.52.4-2.2-2.2-2.22.3-2.1
Patch foraging total patch changes 0 sec0.10.10.7-0.80.5-0.0-0.3-0.20.20.20.2-0.20.2
Patch foraging total patch changes 12 sec3.44.45.6-2.42.3-2.2-2.3-2.21.92.02.0-2.01.7
Patch foraging total patch changes 18 sec1.11.41.8-1.11.3-1.3-1.3-1.21.11.11.1-1.31.1
Patch foraging total patch changes 24 sec0.50.61.4-1.20.9-0.6-0.8-0.30.60.70.7-0.80.8
Patch foraging total patch changes 6 sec4.16.18.7-3.02.7-2.4-2.6-2.42.32.32.3-2.42.3
Patch foraging time to switch 0 sec0.60.91.5-0.40.9-1.1-1.0-1.21.01.01.0-0.90.8
Patch foraging water rate 0 sec0.81.32.00.6-1.11.11.21.1-1.4-1.3-1.31.3-1.0
Patch foraging water rate 12 sec0.20.40.60.3-0.60.80.70.8-0.6-0.6-0.60.7-0.4
Patch foraging water rate 18 sec0.10.20.30.2-0.50.60.50.5-0.4-0.3-0.30.4-0.1
Patch foraging water rate 24 sec0.40.60.70.7-0.70.70.80.5-0.8-0.8-0.80.9-0.7
Patch foraging water rate 6 sec0.10.20.20.3-0.40.30.40.4-0.4-0.4-0.40.4-0.4
Seeking ratio, delayed vs. immediate footshock0.00.10.5-0.70.20.1-0.1-0.00.10.00.0-0.0-0.2
Distance traveled before self-admin0.00.00.10.30.1-0.0-0.2-0.30.20.10.1-0.2-0.3
Distance traveled after self-admin0.70.81.81.3-0.90.80.70.8-0.6-0.7-0.70.6-1.3
Extensor digitorum longus weight0.10.50.70.7-0.80.80.80.9-0.5-0.6-0.60.6-0.2
Bone: elastic displacement0.30.42.41.5-0.70.40.50.3-0.3-0.2-0.20.3-0.1
Bone: elastic work0.30.41.61.3-0.70.40.60.4-0.6-0.5-0.50.7-0.4
Bone: endosteal estimation3.57.78.22.9-2.82.82.82.8-2.8-2.7-2.72.7-2.9
Bone: endosteal perimeter3.77.78.22.8-2.82.92.82.8-2.8-2.7-2.72.7-2.9
Epididymis fat weight2.15.05.62.2-2.22.12.22.2-2.4-2.3-2.32.3-2.0
Delta time in closed arm before/after self-admin0.10.10.5-0.70.3-0.0-0.1-0.0-0.2-0.1-0.10.10.2
Delta time in open arm before/after self-admin1.31.22.01.3-1.10.91.00.7-1.1-1.2-1.21.0-1.4
Diff in mean of infusions in LGA sessions0.70.70.90.7-0.80.70.80.7-0.9-0.9-0.90.9-1.0
Delay discount exponential model param1.51.62.00.7-1.21.41.31.4-1.4-1.4-1.41.4-0.9
Extinction: sum of active levers before priming0.50.50.90.1-0.50.30.60.5-0.9-0.9-0.90.9-0.8
Active lever presses in extinction session 60.30.31.31.1-0.50.00.4-0.1-0.6-0.5-0.50.5-0.7
Bone: final force0.00.00.1-0.20.00.30.10.2-0.2-0.2-0.20.20.1
Bone: final moment0.10.10.30.0-0.20.50.30.4-0.4-0.4-0.40.4-0.1
Food consumed during 24 hour testing period0.81.02.1-1.41.1-0.9-1.0-0.91.00.90.9-0.90.8
Glucose0.10.20.2-0.3-0.30.30.30.4-0.5-0.4-0.40.4-0.5
Heart weight0.10.10.5-0.70.1-0.10.10.1-0.4-0.3-0.30.30.1
Delay discount hyperbolic model param1.01.11.40.4-1.01.11.11.2-1.1-1.2-1.21.2-0.6
Intermittent access intake day 1-15 change1.91.93.01.4-1.51.41.51.7-1.3-1.2-1.21.3-1.1
Intermittent access intake escalation2.22.13.21.6-1.61.61.61.8-1.3-1.2-1.21.3-1.1
Intermittent access intake escalation 21.61.62.51.6-1.41.51.41.6-1.0-0.9-0.91.0-0.7
Intermitt. access day 1 inactive lever presses0.20.20.60.8-0.50.20.40.2-0.3-0.3-0.30.3-0.7
Intermitt. access day 15 inactive lever presses0.00.00.00.0-0.1-0.10.10.0-0.10.10.10.1-0.2
Intermitt. access escalation Index2.42.12.61.2-1.41.31.41.3-1.5-1.6-1.61.5-1.5
Intermittent access day 1 total infusions0.10.10.20.2-0.20.20.20.1-0.3-0.4-0.40.3-0.5
Intermittent access day 15 total infusions2.12.33.21.2-1.61.71.61.8-1.5-1.6-1.61.5-1.3
Intermittent access terminal intake (last 3 days)0.91.01.51.0-1.01.11.01.2-0.9-0.9-0.90.9-0.7
Intermittent access total infusions0.70.81.00.8-0.90.90.91.0-0.8-0.9-0.90.8-0.7
Intermittent access day 1 locomotion0.30.30.40.3-0.50.70.50.6-0.6-0.6-0.60.4-0.5
Intermittent access day 15 total locomotion1.01.01.5-0.81.0-0.8-1.0-0.71.11.11.1-1.21.2
Intermittent access total locomotion0.50.60.9-0.50.7-0.6-0.7-0.60.80.90.9-0.91.0
Intermittent access standard deviation1.01.11.60.9-1.11.31.11.2-1.0-1.0-1.01.0-0.7
Left kidney weight0.10.32.1-1.50.6-0.2-0.4-0.20.10.10.1-0.00.1
Right kidney weight0.41.05.2-2.31.2-0.8-0.9-0.80.40.50.5-0.40.7
Cocaine induced anxiety0.10.10.20.4-0.20.00.20.0-0.2-0.2-0.20.2-0.5
Post-drug Anxiety0.10.10.10.30.1-0.4-0.2-0.40.20.20.2-0.3-0.1
Baseline Anxiety0.00.00.0-0.20.1-0.1-0.1-0.10.20.10.1-0.20.1
Tail length0.10.40.5-0.6-0.30.70.50.6-0.6-0.7-0.70.7-0.5
Length with tail0.10.42.7-1.70.5-0.0-0.30.00.10.20.2-0.10.6
Length without tail0.30.72.8-1.70.9-0.5-0.7-0.30.60.70.7-0.61.2
Times rat made contact with spout0.20.30.5-0.20.5-0.5-0.6-0.50.70.60.6-0.70.1
Lifetime Intake0.20.20.20.4-0.40.40.40.4-0.4-0.5-0.50.4-0.4
Liver weight, left0.20.30.80.3-0.50.90.60.8-0.4-0.5-0.50.5-0.4
Liver weight, right0.71.21.60.4-1.01.21.11.2-1.2-1.2-1.21.2-0.9
Locomotor activity0.00.00.1-0.30.1-0.2-0.1-0.2-0.1-0.0-0.00.1-0.1
Locomotor testing distance0.00.00.1-0.30.1-0.1-0.0-0.2-0.2-0.1-0.10.2-0.2
Locomotor testing rearing0.30.40.60.7-0.70.60.60.5-0.7-0.6-0.60.6-0.7
Locomotion in novel chamber2.12.53.31.8-1.71.21.61.4-1.7-1.7-1.71.7-1.6
Locomotion in novel chamber post-restriction0.10.20.6-0.80.5-0.5-0.4-0.30.20.30.3-0.20.2
Fecal boli incidents, locomotor time 10.10.10.20.00.3-0.4-0.4-0.40.30.30.3-0.30.4
Change in fecal boli incidents, locomotor task0.00.00.1-0.30.10.0-0.0-0.0-0.00.00.00.0-0.0
Time >=10cm from walls, locomotor time 10.60.63.1-1.80.8-0.4-0.6-0.50.60.60.6-0.50.7
Bouts of movement, locomotor time 12.22.42.9-1.11.5-1.6-1.5-1.71.71.71.7-1.61.3
Total resting periods, locomotor time 13.94.24.8-1.72.0-2.2-2.0-2.22.22.22.2-2.11.8
Rest time, locomotor task time 11.21.31.9-0.41.0-1.4-1.1-1.41.31.31.3-1.20.8
Distance moved, locomotor task time 11.01.11.7-0.1-0.81.31.01.3-1.2-1.2-1.21.2-0.7
Vertical activity count, locomotor time 10.40.50.7-0.3-0.40.80.60.8-0.8-0.7-0.70.7-0.5
Time >=10cm from walls, locomotor time 20.30.31.1-1.00.7-0.4-0.6-0.50.50.40.4-0.50.5
Bouts of movement, locomotor time 23.94.25.5-1.52.0-2.3-2.2-2.12.22.22.2-2.21.4
Total resting periods, locomotor time 24.64.96.4-1.72.2-2.5-2.3-2.22.42.32.3-2.31.6
Rest time, locomotor task time 22.93.33.9-1.31.7-1.9-1.8-1.91.82.02.0-1.91.9
Distance moved, locomotor task time 21.21.42.10.5-1.01.41.21.3-1.2-1.3-1.31.2-1.0
Vertical activity count, locomotor time 20.20.20.50.0-0.30.50.30.5-0.4-0.5-0.50.4-0.7
Light reinforcement 10.10.10.20.30.2-0.1-0.3-0.30.40.40.4-0.30.2
Light reinforcement 22.02.63.3-0.81.6-1.7-1.7-1.71.71.81.8-1.61.4
Bone: marrow area3.67.88.42.9-2.82.82.82.8-2.8-2.7-2.72.7-2.9
Bone: maximum diameter4.37.98.82.7-2.83.02.92.9-2.9-2.8-2.82.8-2.5
Bone: maximum force0.10.20.30.4-0.30.50.40.4-0.5-0.4-0.40.4-0.0
Bone: maximum moment0.20.40.50.6-0.50.70.60.6-0.7-0.6-0.60.6-0.3
Mean time between licks in bursts0.10.10.30.0-0.30.50.40.5-0.4-0.3-0.30.4-0.1
Mean num. licks in bursts2.12.53.21.1-1.51.81.61.7-1.6-1.6-1.61.7-1.6
Cd content in liver0.50.50.8-0.90.7-0.6-0.7-0.60.80.70.7-0.80.6
Co content in liver0.20.30.40.1-0.40.60.50.6-0.6-0.5-0.50.5-0.6
Cu content in liver7.08.59.7-2.12.9-3.1-3.1-3.13.13.13.1-3.12.5
Fe content in liver1.41.62.1-0.71.2-1.3-1.3-1.31.41.41.4-1.31.4
K content in liver0.50.50.7-0.40.7-0.9-0.8-0.90.80.70.7-0.80.3
Mg content in liver1.01.01.3-0.61.0-1.2-1.0-1.21.01.01.0-1.10.9
Mn content in liver7.18.19.4-1.82.8-3.1-2.9-3.13.02.92.9-3.02.7
Na content in liver1.71.82.5-0.81.3-1.6-1.4-1.61.31.31.3-1.31.4
Rb content in liver0.20.30.5-0.30.6-0.6-0.5-0.60.50.50.5-0.60.7
Se content in liver19.924.327.1-3.94.9-5.0-5.1-5.05.25.25.2-5.14.6
Sr content in liver0.10.10.1-0.40.3-0.3-0.3-0.30.20.30.3-0.30.1
Zn content in liver0.91.01.2-0.81.0-1.0-1.0-1.01.01.01.0-1.11.0
Bone: minimum diameter7.914.817.13.1-3.84.03.94.0-4.1-4.1-4.14.0-3.3
Time in familiar zone, hab. session 10.20.20.60.8-0.40.30.40.3-0.4-0.4-0.40.3-0.3
Time in novel zone, hab. session 10.60.60.8-0.70.7-0.6-0.7-0.60.90.90.9-0.90.8
Total zone transitions, hab. session 10.30.40.6-0.20.6-0.6-0.6-0.60.70.80.8-0.70.5
Total locomotion distance, hab. session 12.43.43.9-1.61.8-1.8-1.9-1.82.02.02.0-1.91.7
Locomotion velocity, hab. session 13.75.35.8-2.22.3-2.2-2.3-2.22.42.42.4-2.32.1
Time in familiar zone, hab. session 20.50.50.70.6-0.70.50.70.5-0.8-0.8-0.80.8-0.6
Time in novel zone, hab. session 20.80.81.0-0.80.9-0.7-0.9-0.71.01.01.0-1.00.8
Total zone transitions, hab. session 20.20.30.4-0.40.5-0.4-0.5-0.40.60.60.6-0.60.4
Total locomotion distance, hab. session 20.50.70.8-0.90.9-0.9-0.9-0.90.90.90.9-0.90.7
Locomotion velocity, hab. session 20.71.01.1-0.91.0-1.0-1.0-1.01.11.01.0-1.00.8
Novel to familiar place preference ratio0.20.20.80.90.0-0.4-0.2-0.40.50.50.5-0.4-0.1
Novelty place preference0.20.21.01.0-0.0-0.3-0.2-0.30.50.40.4-0.4-0.1
Time in novel zone, NPP test0.20.21.11.0-0.0-0.2-0.2-0.20.60.50.5-0.5-0.0
Total zone transitions, NPP test0.50.71.4-1.20.8-0.6-0.8-0.60.90.80.8-0.90.6
Total locomotion distance, NPP test3.14.25.3-2.32.1-2.0-2.1-2.02.12.12.1-2.11.7
Locomotion velocity, NPP test2.43.35.3-2.31.9-1.8-1.9-1.81.81.71.7-1.81.4
Intraocular pressure0.00.10.30.5-0.3-0.20.20.0-0.3-0.2-0.20.2-0.1
Delta distance traveled before/after self-admin2.52.73.51.9-1.71.61.71.8-1.5-1.5-1.51.5-1.6
Delta ambulatory time before/after self-admin3.43.74.52.1-2.11.92.02.1-1.8-1.8-1.81.9-1.9
Parametrial fat weight0.20.41.5-1.2-0.10.40.30.6-0.6-0.7-0.70.6-0.3
Pavlov. Cond. lever latency0.20.20.60.8-0.60.50.50.5-0.3-0.3-0.30.3-0.2
Pavlov. Cond. magazine entry latency0.81.03.8-1.91.1-0.9-1.0-0.90.80.80.8-0.80.4
Pavlov. Cond. change in total contacts0.10.11.1-1.00.4-0.2-0.3-0.20.0-0.0-0.0-0.0-0.1
Pavlov. Cond. index score0.91.13.1-1.81.2-1.0-1.1-1.00.90.90.9-0.90.6
Pavlov. Cond. latency score0.50.72.5-1.61.0-0.8-0.9-0.80.60.60.6-0.60.3
Pavlov. Cond. lever contacts0.60.72.0-1.41.0-0.8-0.8-0.80.60.70.7-0.70.6
Pavlov. Cond. magazine entry number0.10.11.01.0-0.40.10.30.1-0.2-0.2-0.20.20.3
Pavlov. Cond. intertrial magazine entries0.30.40.7-0.40.5-0.4-0.5-0.40.70.60.6-0.70.9
Pavlov. Cond. lever-magazine prob. diff.0.91.12.9-1.71.2-1.0-1.1-1.01.00.90.9-0.90.6
Pavlov. Cond. response bias0.40.52.0-1.40.8-0.5-0.7-0.50.70.60.6-0.60.2
Pavlov. Cond. lever latency0.91.23.82.0-1.21.11.11.1-0.8-0.8-0.80.8-0.4
Pavlov. Cond. magazine entry latency0.40.51.6-1.30.7-0.6-0.7-0.50.60.50.5-0.50.4
Pavlov. Cond. change in total contacts0.10.21.0-1.00.4-0.3-0.3-0.30.10.00.0-0.1-0.3
Pavlov. Cond. index score1.01.33.9-2.01.2-1.1-1.2-1.11.00.90.9-0.90.5
Pavlov. Cond. latency score1.01.33.8-1.91.2-1.1-1.2-1.11.00.90.9-0.90.5
Pavlov. Cond. lever contacts0.50.73.1-1.80.9-0.8-0.9-0.80.60.50.5-0.60.2
Pavlov. Cond. magazine entry number2.53.07.02.6-1.91.61.81.6-1.7-1.5-1.51.6-1.2
Pavlov. Cond. intertrial magazine entries0.81.02.71.6-1.10.91.00.9-0.8-0.8-0.80.8-0.9
Pavlov. Cond. lever-magazine prob. diff.1.01.34.0-2.01.3-1.1-1.2-1.11.00.90.9-0.90.5
Pavlov. Cond. response bias0.91.24.2-2.01.2-1.0-1.1-1.00.90.80.8-0.90.4
Time in closed arm before self-admin0.10.10.30.50.0-0.1-0.1-0.20.50.50.5-0.40.1
Time in closed arm after self-admin1.11.12.2-0.40.8-0.5-0.8-0.51.21.41.4-1.21.5
Time in open arm before self-admin0.10.10.30.5-0.30.30.30.3-0.2-0.2-0.20.2-0.4
Time in open arm after self-admin1.31.52.90.9-1.00.61.00.7-1.4-1.5-1.51.3-1.7
Bone: periosteal estimation2.34.85.41.9-2.12.32.22.2-2.3-2.2-2.22.2-2.0
Bone: periosteal perimeter3.25.35.92.1-2.32.42.32.4-2.4-2.3-2.32.3-2.0
Bone: post-yield work0.30.40.50.5-0.60.70.70.7-0.7-0.7-0.70.7-0.5
Progressive ratio test 1 active lever presses0.10.10.40.6-0.20.30.20.2-0.1-0.0-0.00.10.1
Progressive ratio test 1 breakpoint0.10.10.50.7-0.30.40.20.3-0.1-0.1-0.10.2-0.0
Progressive ratio test 1 inactive lever presses2.12.33.21.5-1.51.11.41.2-1.8-1.6-1.61.7-1.7
Progressive ratio test 2 active lever presses0.10.10.20.4-0.20.20.10.30.20.30.3-0.10.3
Progressive ratio test 2 breakpoint0.00.00.10.4-0.10.10.00.30.20.20.2-0.20.3
Progressive ratio test 2 inactive lever presses0.10.10.40.6-0.2-0.10.00.10.20.30.3-0.20.1
Incentive Sensitization - Responses0.20.20.50.6-0.60.40.50.7-0.2-0.3-0.30.2-0.5
Incentive Sensitization - Breakpoint0.10.10.30.4-0.40.20.30.5-0.1-0.2-0.20.1-0.3
Sum of active levers in priming session hrs 5-60.00.00.00.2-0.0-0.2-0.0-0.20.10.00.0-0.1-0.1
Progressive ratio1.01.11.80.5-0.91.01.00.7-1.2-1.3-1.31.2-1.0
Food seeking constrained by brief footshock0.30.31.6-1.30.6-0.5-0.5-0.50.40.10.1-0.40.5
Seeking ratio, punishment vs. effort1.41.71.9-1.31.3-1.3-1.3-1.01.31.31.3-1.41.3
Retroperitoneal fat weight0.72.23.20.9-1.31.21.41.2-1.8-1.8-1.81.7-1.3
Reaction time number correct1.01.54.52.1-1.51.41.31.2-0.8-0.8-0.80.9-0.7
Reaction time mean minus median0.40.50.7-0.4-0.60.60.60.8-0.8-0.8-0.80.8-0.8
Reaction time mean minus median AUC0.50.60.9-0.1-0.60.60.70.8-1.0-0.9-0.90.9-0.9
Reaction time num false alarms0.10.10.7-0.10.00.40.10.20.20.20.2-0.20.8
Reaction time num false alarms AUC0.10.10.4-0.2-0.10.50.20.4-0.00.00.00.00.6
Reaction time trials correct on left1.01.54.52.1-1.51.41.31.2-0.8-0.8-0.80.9-0.7
Reaction time trials on left1.01.54.32.1-1.51.41.31.2-0.8-0.8-0.80.9-0.7
Reaction time mean0.20.31.6-1.30.6-0.5-0.5-0.30.30.30.3-0.30.3
Reaction time mean AUC0.30.52.0-1.40.7-0.7-0.6-0.50.40.50.5-0.50.4
Median of all reaction times0.30.41.2-1.10.6-0.7-0.6-0.40.50.50.5-0.50.4
Reaction time omissions1.11.62.00.2-1.21.21.31.4-1.3-1.3-1.31.4-1.4
Reaction time false alarm rate0.20.31.3-1.20.6-0.2-0.4-0.30.40.40.4-0.40.9
Reaction time premature initiation rate0.10.21.3-1.10.40.2-0.20.20.1-0.0-0.0-0.10.4
Reaction time premature initiations0.20.20.8-0.1-0.40.90.50.8-0.3-0.5-0.50.40.0
Std. dev. reaction times0.30.40.6-0.8-0.40.60.50.7-0.7-0.7-0.70.6-0.7
Reaction time trials completed1.01.54.32.1-1.51.41.31.2-0.8-0.8-0.80.9-0.7
Reaction time trials AUC0.91.34.22.0-1.41.31.21.1-0.7-0.7-0.70.8-0.6
Run reversals in cocaine runway, females0.90.81.30.10.7-0.7-0.8-1.01.11.11.1-1.10.9
Run reversals in cocaine runway, males3.23.14.8-2.21.9-1.8-1.7-1.81.51.61.6-1.61.8
Latency to leave start box in cocaine runway4.34.76.12.5-2.32.22.22.3-2.0-2.0-2.02.0-2.0
Latency to leave start box in cocaine runway, F5.15.67.52.7-2.52.32.42.4-2.2-2.2-2.22.2-2.4
Latency to leave start box in cocaine runway, M0.60.61.10.8-0.81.10.81.1-0.6-0.6-0.60.6-0.7
Std. dev. time between licks in bursts0.40.50.7-0.40.6-0.6-0.7-0.70.70.80.8-0.60.8
Total sessions with >9 infusions0.20.30.5-0.10.4-0.3-0.5-0.30.50.70.7-0.50.6
Short access day 1 total inactive lever presses2.32.54.62.1-1.61.01.41.1-1.6-1.6-1.61.5-2.0
Short access day 10 total inactive lever presses0.10.10.3-0.1-0.0-0.5-0.0-0.4-0.3-0.0-0.00.2-0.2
Short access day 1 total infusions0.60.61.0-0.50.8-1.0-0.8-0.90.70.80.8-0.80.7
Short access day 10 total infusions0.10.10.2-0.40.3-0.3-0.3-0.40.30.30.3-0.30.2
Short access total infusions0.10.10.2-0.20.3-0.5-0.3-0.40.10.20.2-0.20.1
Short access day 1 locomotion0.10.10.91.0-0.30.30.10.40.10.30.3-0.20.1
Short access day 10 total locomotion0.10.10.3-0.30.4-0.4-0.4-0.50.30.30.3-0.40.4
Short access total locomotion0.10.10.20.10.2-0.2-0.3-0.30.30.40.4-0.40.1
One hour access (0.3 mA shock)0.50.61.01.0-0.90.90.80.9-0.7-0.7-0.70.7-0.6
Compulsive drug intake3.83.85.31.1-1.81.61.91.5-2.3-2.3-2.32.3-2.1
One hour access (shock baseline)0.20.20.60.8-0.50.60.40.7-0.2-0.2-0.20.1-0.2
Social response proportion1.71.94.12.0-1.51.11.31.5-1.0-1.2-1.21.0-1.5
Social responses1.51.93.21.3-1.31.21.21.4-1.3-1.4-1.41.3-1.8
Social time0.00.00.1-0.30.20.0-0.20.00.20.20.2-0.2-0.1
Soleus weight0.92.53.21.8-1.61.61.61.6-1.5-1.5-1.51.4-1.8
Bone: stiffness0.10.20.4-0.0-0.30.60.40.6-0.5-0.4-0.40.40.1
Tibialis anterior weight0.31.01.21.1-1.11.01.11.0-0.8-0.9-0.91.0-0.8
Time to tail flick, vehicle, before self-admin0.40.40.50.00.5-0.7-0.7-0.70.70.70.7-0.70.3
Time to tail flick, vehicle, after self-admin0.20.30.50.7-0.60.60.60.6-0.3-0.4-0.40.3-0.3
Time to tail flick, test, before self-admin0.70.71.01.0-0.90.80.80.8-0.8-0.8-0.80.7-1.0
Time to tail flick, test, after self-admin0.70.71.91.4-0.90.90.80.8-0.7-0.6-0.60.5-0.8
Delta time to tail flick, vehicle, before/after SA0.20.20.40.4-0.50.70.60.6-0.5-0.4-0.40.4-0.1
Delta time to tail flick, test, before/after SA0.00.00.10.2-0.0-0.0-0.00.1-0.00.10.1-0.10.2
Tibia length0.00.10.2-0.4-0.00.30.20.2-0.4-0.4-0.40.3-0.2
Ambulatory time before self-admin0.10.10.20.20.3-0.2-0.4-0.40.30.30.3-0.40.0
Ambulatory time after self-admin0.70.72.61.6-0.90.80.70.8-0.5-0.5-0.50.5-1.0
Bone: tissue strength0.20.10.20.3-0.40.40.40.3-0.4-0.4-0.40.4-0.4
Total heroin consumption0.30.41.1-1.00.6-0.9-0.4-0.9-0.3-0.3-0.30.3-0.6
Bone: trabecular number0.91.42.11.4-1.21.01.11.0-1.1-1.1-1.11.1-1.4
Bone: trabecular spacing0.20.31.5-1.20.5-0.3-0.4-0.30.30.40.4-0.30.7
Bone: trabecular thickness1.31.51.81.1-1.21.31.21.2-1.3-1.3-1.31.3-1.3
Bone: trabecular tissue density0.70.91.41.2-1.01.01.01.0-1.0-0.9-0.91.0-0.6
Water consumed over 24 hours0.30.30.6-0.00.4-0.5-0.6-0.50.80.70.7-0.80.3
Number of responses in last shaping day0.10.10.30.6-0.30.40.30.50.00.10.10.00.5