Hub : Genes

LOC120097050

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	alternative polyA	XR_005494140.1	0.03	0.02	1.2e-04	0.01	0.03	0.01	0.01	6.0e-03	4.7e-04	6.7e-03	8.4e-03
2	NAcc	alternative polyA	XR_005494145.1	0.03	0.02	1.6e-04	0.01	0.03	0.02	0.01	6.7e-03	5.2e-04	3.6e-03	8.0e-03
3	OFC	alternative polyA	XR_005494140.1	0.33	0.25	5.8e-04	0.14	0.09	0.11	0.13	2.7e-04	3.4e-03	1.7e-03	5.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.6	1.0	1.2	-1.1	1.1	0.8
Area under the delay curve	0.2	0.2	0.3	-0.4	0.4	0.6
BMI with tail	0.1	0.5	0.6	0.8	-0.8	-0.4
BMI without tail	0.0	0.0	0.1	-0.2	0.2	0.1
Body weight	3.0	12.6	13.1	-3.6	3.6	3.4
Weight adjusted by age	0.3	0.3	0.6	-0.4	0.4	0.8
Bone surface	1.5	2.6	3.1	-1.8	1.8	1.3
Bone volume	1.6	2.6	3.1	-1.7	1.8	1.3
Breakpoint value in progressive ratio session	1.2	1.4	1.6	-1.1	1.1	1.3
Number of licking bursts	3.2	3.8	4.2	2.1	-2.0	-1.7
Context. condit. distance diff. score	0.1	0.1	0.3	0.1	-0.1	0.5
Locomotion velocity, session 1	0.5	0.6	0.7	0.7	-0.7	-0.8
Locomotion distance, session 1	0.5	0.6	0.6	-0.8	0.8	0.7
Locomotion velocity, session 2	1.5	1.8	3.5	1.0	-1.0	-1.9
Locomotion distance, session 2	1.6	2.2	3.0	1.4	-1.4	-1.7
Locomotion velocity, session 3	0.5	0.5	1.0	0.6	-0.5	-1.0
Locomotion distance, session 3	2.2	2.4	2.8	-1.7	1.7	1.2
Stereotopy head waving bouts, day 3	0.7	0.9	1.2	0.9	-0.9	-1.1
Stereotopy head waving duration, day 3	1.5	1.8	1.8	1.3	-1.3	-1.3
Locomotion velocity, session 7	0.3	0.4	0.4	-0.6	0.6	0.6
Locomotion distance, session 7	0.1	0.2	0.2	-0.5	0.5	0.2
Stereotopy head waving bouts, day 7	1.2	1.4	1.4	1.2	-1.2	-1.1
Stereotopy head waving duration, day 7	2.4	2.9	3.2	1.8	-1.8	-1.5
Locomotion velocity, session 8	3.9	4.7	5.0	2.2	-2.2	-2.0
Locomotion distance, session 8	0.6	0.9	1.0	1.0	-1.0	-0.9
Degree of sensitization distance	0.3	0.3	0.4	0.6	-0.6	-0.5
Degree of sensitization stereotypy	1.4	1.6	1.7	1.3	-1.3	-1.1
Conditioned locomotion	0.6	0.7	0.9	0.9	-1.0	-0.6
Cocaine response after cond. corrected	0.0	0.0	0.1	0.3	-0.3	-0.0
Cocaine response after cond. not corrected	0.0	0.0	0.1	0.1	-0.1	-0.3
Cocaine response before conditioning	0.9	1.1	1.6	-1.3	1.3	0.3
Saline control response	0.0	0.0	0.0	-0.0	0.0	-0.2
Bone: connectivity density	0.2	0.3	0.4	-0.6	0.6	0.1
Bone: cortical apparent density	1.4	1.9	2.4	1.6	-1.5	-0.9
Bone: cortical area	1.3	1.9	2.1	-1.5	1.5	1.2
Bone: cortical porosity	2.6	2.8	4.2	1.5	-1.5	-2.0
Bone: cortical porosity	3.2	3.5	4.9	1.7	-1.7	-2.2
Bone: cortical thickness	0.2	0.4	0.5	-0.7	0.7	0.5
Bone: cortical thickness	0.7	0.8	0.8	0.9	-0.9	-0.9
Bone: cortical tissue density	1.7	2.3	2.8	1.7	-1.7	-1.0
Condit. Reinf. active minus inactive responses	0.2	0.2	0.3	0.5	-0.5	-0.3
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.2	0.5	-0.5	-0.3
Condit. Reinf. active responses	2.1	2.5	2.9	1.7	-1.7	-1.3
Condit. Reinf. inactive responses	2.2	2.7	2.9	1.7	-1.7	-1.5
Incentive salience index mean	0.2	0.3	0.3	0.5	-0.5	-0.6
Condit. Reinf. lever presses	0.0	0.1	0.2	0.1	-0.1	-0.4
Condit. Reinf. active minus inactive responses	1.0	1.2	1.7	-1.3	1.3	0.5
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	0.2	-0.2	-0.3
Condit. Reinf. active responses	2.6	3.6	4.7	-2.2	2.2	1.2
Condit. Reinf. inactive responses	3.3	4.0	5.1	-2.2	2.2	1.4
Condit. Reinf. lever presses	6.4	8.7	10.2	-3.2	3.2	2.4
Condit. Reinf. lever reinforcers received	2.8	3.9	5.0	-2.2	2.2	1.3
Conditioned reinforcement - actives	0.7	0.7	1.5	0.5	-0.5	-1.2
Conditioned reinforcement - inactives	0.2	0.2	0.3	-0.5	0.5	0.2
Conditioned locomotion	2.8	3.4	3.7	1.8	-1.8	-1.9
Patch foraging indifference point 0 sec	0.0	0.0	0.1	-0.2	0.2	-0.1
Patch foraging indifference point AUC	0.5	0.5	0.6	0.7	-0.7	-0.8
Delay disc. indifference point, 0s delay	0.3	0.3	0.8	-0.1	0.1	0.9
Delay disc. indifference point, 16s delay	0.3	0.3	0.4	-0.6	0.6	0.5
Delay disc. indifference point, 2s delay	1.3	1.5	2.3	-1.0	1.0	1.5
Delay disc. indifference point, 24s delay	2.3	2.2	2.3	-1.5	1.5	1.5
Delay disc. indifference point, 4s delay	0.2	0.2	0.4	0.4	-0.4	-0.6
Delay disc. indifference point, 8s delay	0.2	0.2	0.3	-0.4	0.4	0.5
Indifference point function ln k	0.4	0.5	0.6	-0.8	0.8	0.6
Indifference point function log k	0.4	0.5	0.6	-0.8	0.8	0.6
Patch foraging total patch changes 0 sec	0.1	0.1	0.2	-0.4	0.4	0.1
Patch foraging total patch changes 12 sec	0.2	0.2	0.5	0.2	-0.2	-0.7
Patch foraging total patch changes 18 sec	0.0	0.0	0.0	0.1	-0.1	-0.1
Patch foraging total patch changes 24 sec	0.9	1.1	1.4	-1.0	1.0	1.2
Patch foraging total patch changes 6 sec	0.0	0.1	0.2	-0.1	0.1	-0.4
Patch foraging time to switch 0 sec	0.8	1.2	1.6	1.0	-1.0	-1.2
Patch foraging water rate 0 sec	0.6	0.9	0.9	1.0	-1.0	-1.0
Patch foraging water rate 12 sec	0.5	0.8	0.9	-0.9	0.9	0.8
Patch foraging water rate 18 sec	0.2	0.3	0.5	0.5	-0.4	-0.7
Patch foraging water rate 24 sec	0.0	0.0	0.0	0.0	-0.0	0.1
Patch foraging water rate 6 sec	1.1	1.6	1.6	-1.3	1.3	1.2
Seeking ratio, delayed vs. immediate footshock	1.0	1.2	1.3	-1.1	1.1	1.2
Distance traveled before self-admin	0.0	0.0	0.0	0.1	-0.1	-0.1
Distance traveled after self-admin	3.3	3.7	4.3	-2.1	2.1	1.6
Extensor digitorum longus weight	0.0	0.2	0.2	0.4	-0.4	0.5
Bone: elastic displacement	0.0	0.0	0.1	0.0	-0.0	-0.2
Bone: elastic work	1.6	2.1	2.4	-1.6	1.6	1.2
Bone: endosteal estimation	1.5	3.2	3.6	-1.9	1.9	1.5
Bone: endosteal perimeter	1.3	2.6	3.0	-1.7	1.7	1.3
Epididymis fat weight	0.2	0.4	0.5	-0.5	0.5	0.7
Delta time in closed arm before/after self-admin	3.5	3.4	3.6	-1.8	1.8	1.9
Delta time in open arm before/after self-admin	1.0	0.9	1.5	0.8	-0.8	-1.2
Diff in mean of infusions in LGA sessions	0.4	0.5	0.6	0.8	-0.8	-0.4
Delay discount exponential model param	0.3	0.3	0.4	0.5	-0.5	-0.6
Extinction: sum of active levers before priming	4.6	4.6	5.4	-2.0	2.0	2.3
Active lever presses in extinction session 6	2.4	2.4	3.0	-1.7	1.7	1.1
Bone: final force	1.8	2.9	3.0	-1.7	1.7	1.7
Bone: final moment	2.3	3.8	3.8	-1.9	1.9	1.9
Food consumed during 24 hour testing period	0.6	0.7	0.7	-0.9	0.9	0.7
Glucose	0.1	0.1	0.2	0.4	-0.4	-0.2
Heart weight	0.3	0.4	0.6	-0.5	0.5	0.8
Delay discount hyperbolic model param	0.2	0.2	0.3	0.4	-0.4	-0.6
Intermittent access intake day 1-15 change	2.8	2.8	3.0	-1.7	1.7	1.5
Intermittent access intake escalation	2.8	2.8	3.0	-1.7	1.7	1.6
Intermittent access intake escalation 2	1.6	1.6	1.9	-1.4	1.4	1.0
Intermitt. access day 1 inactive lever presses	3.1	3.3	3.7	-1.9	1.9	1.6
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.3	-0.6	0.5	0.2
Intermitt. access escalation Index	0.1	0.1	0.1	0.3	-0.3	0.0
Intermittent access day 1 total infusions	2.8	3.3	3.3	1.8	-1.8	-1.8
Intermittent access day 15 total infusions	0.1	0.1	0.2	0.2	-0.2	-0.5
Intermittent access terminal intake (last 3 days)	0.5	0.6	0.9	0.7	-0.6	-1.0
Intermittent access total infusions	1.0	1.1	1.5	0.9	-0.9	-1.2
Intermittent access day 1 locomotion	1.4	1.5	1.5	1.2	-1.2	-1.2
Intermittent access day 15 total locomotion	0.0	0.0	0.1	0.1	-0.1	-0.3
Intermittent access total locomotion	1.6	1.8	2.0	1.3	-1.3	-1.4
Intermittent access standard deviation	4.6	4.8	5.5	-2.3	2.3	1.9
Left kidney weight	3.3	9.3	9.6	-3.1	3.1	2.9
Right kidney weight	5.4	15.3	16.3	-4.0	4.0	3.6
Cocaine induced anxiety	0.5	0.6	0.6	-0.8	0.7	0.8
Post-drug Anxiety	0.1	0.1	0.2	0.3	-0.3	-0.4
Baseline Anxiety	1.7	1.8	2.1	1.3	-1.3	-1.5
Tail length	4.5	13.6	15.6	-3.9	3.9	3.1
Length with tail	8.3	30.5	33.0	-5.7	5.7	5.0
Length without tail	6.2	13.6	14.0	-3.7	3.7	3.6
Times rat made contact with spout	0.2	0.2	0.4	0.6	-0.6	0.0
Lifetime Intake	1.0	1.2	1.5	1.0	-1.0	-1.2
Liver weight, left	0.2	0.3	0.5	0.7	-0.7	-0.2
Liver weight, right	0.2	0.4	0.7	0.4	-0.5	-0.8
Locomotor activity	0.5	0.8	1.2	0.8	-0.8	-1.1
Locomotor testing distance	0.4	0.7	0.9	0.7	-0.7	-1.0
Locomotor testing rearing	1.8	2.7	2.8	1.7	-1.6	-1.7
Locomotion in novel chamber	0.3	0.4	0.6	0.6	-0.6	-0.8
Locomotion in novel chamber post-restriction	0.0	0.0	0.0	0.1	-0.1	-0.1
Fecal boli incidents, locomotor time 1	2.8	3.1	4.0	1.6	-1.6	-2.0
Change in fecal boli incidents, locomotor task	0.1	0.1	0.1	-0.3	0.3	0.2
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.0	0.2	-0.2	-0.0
Bouts of movement, locomotor time 1	0.5	0.5	0.8	-0.6	0.6	0.9
Total resting periods, locomotor time 1	0.3	0.3	0.4	-0.5	0.5	0.7
Rest time, locomotor task time 1	1.2	1.4	1.4	1.2	-1.2	-1.2
Distance moved, locomotor task time 1	0.4	0.4	1.1	-0.3	0.3	1.0
Vertical activity count, locomotor time 1	2.3	2.4	2.5	-1.6	1.6	1.5
Time >=10cm from walls, locomotor time 2	2.2	2.3	2.4	1.5	-1.5	-1.4
Bouts of movement, locomotor time 2	0.0	0.0	0.0	0.1	-0.1	-0.0
Total resting periods, locomotor time 2	0.1	0.1	0.2	0.3	-0.3	-0.5
Rest time, locomotor task time 2	0.8	0.9	1.6	0.8	-0.8	-1.2
Distance moved, locomotor task time 2	0.1	0.2	0.4	0.2	-0.2	0.6
Vertical activity count, locomotor time 2	1.1	1.2	1.6	-1.0	1.0	1.3
Light reinforcement 1	0.2	0.3	0.5	0.4	-0.4	-0.7
Light reinforcement 2	2.4	3.3	3.5	1.9	-1.9	-1.7
Bone: marrow area	1.5	3.2	3.7	-1.9	1.9	1.5
Bone: maximum diameter	1.4	2.5	2.7	-1.6	1.6	1.5
Bone: maximum force	2.8	4.9	5.0	-2.2	2.2	2.2
Bone: maximum moment	3.4	5.8	5.8	-2.4	2.4	2.4
Mean time between licks in bursts	0.0	0.0	0.0	0.1	-0.1	-0.2
Mean num. licks in bursts	1.7	2.0	2.2	-1.4	1.4	1.5
Cd content in liver	0.1	0.1	0.2	-0.3	0.3	0.4
Co content in liver	0.3	0.3	0.4	0.6	-0.6	-0.5
Cu content in liver	0.7	0.9	1.2	-0.8	0.8	1.1
Fe content in liver	0.0	0.0	0.0	0.2	-0.2	0.0
K content in liver	0.1	0.1	0.2	0.0	-0.0	-0.4
Mg content in liver	0.9	0.9	1.3	0.8	-0.8	-1.1
Mn content in liver	1.6	1.8	2.7	1.1	-1.1	-1.6
Na content in liver	1.1	1.1	1.4	-1.2	1.2	0.8
Rb content in liver	0.1	0.1	0.1	0.3	-0.3	0.3
Se content in liver	7.5	9.2	9.8	3.1	-3.1	-2.8
Sr content in liver	1.2	1.1	1.6	0.9	-0.9	-1.3
Zn content in liver	0.1	0.1	0.1	0.3	-0.3	-0.0
Bone: minimum diameter	2.6	4.9	5.5	-2.3	2.3	1.9
Time in familiar zone, hab. session 1	1.0	0.9	1.5	-0.8	0.8	1.2
Time in novel zone, hab. session 1	2.2	2.1	2.6	1.4	-1.4	-1.6
Total zone transitions, hab. session 1	0.0	0.0	0.0	0.1	-0.1	-0.1
Total locomotion distance, hab. session 1	0.4	0.6	0.9	-1.0	1.0	0.0
Locomotion velocity, hab. session 1	0.3	0.4	0.5	-0.7	0.7	-0.2
Time in familiar zone, hab. session 2	1.6	1.7	2.0	-1.4	1.4	1.0
Time in novel zone, hab. session 2	1.2	1.2	1.3	1.1	-1.1	-1.0
Total zone transitions, hab. session 2	3.8	5.0	5.3	2.2	-2.2	-2.3
Total locomotion distance, hab. session 2	0.4	0.6	1.0	0.6	-0.6	-1.0
Locomotion velocity, hab. session 2	0.5	0.7	1.1	0.7	-0.7	-1.1
Novel to familiar place preference ratio	0.1	0.1	0.2	-0.3	0.3	0.5
Novelty place preference	0.1	0.1	0.2	-0.2	0.2	0.4
Time in novel zone, NPP test	0.0	0.0	0.1	-0.0	0.0	0.3
Total zone transitions, NPP test	0.1	0.1	0.1	0.2	-0.2	-0.4
Total locomotion distance, NPP test	1.7	2.3	3.0	-1.7	1.7	1.0
Locomotion velocity, NPP test	1.6	2.3	3.1	-1.8	1.8	0.8
Intraocular pressure	0.0	0.0	0.0	0.1	-0.1	0.2
Delta distance traveled before/after self-admin	5.1	5.5	5.8	-2.4	2.4	2.2
Delta ambulatory time before/after self-admin	5.6	6.2	6.7	-2.6	2.6	2.3
Parametrial fat weight	0.0	0.0	0.0	0.1	-0.1	-0.2
Pavlov. Cond. lever latency	0.8	1.1	2.3	-0.7	0.7	1.5
Pavlov. Cond. magazine entry latency	1.5	1.9	3.9	0.9	-0.9	-2.0
Pavlov. Cond. change in total contacts	1.1	1.2	2.4	0.8	-0.8	-1.6
Pavlov. Cond. index score	1.8	2.3	4.5	1.1	-1.1	-2.1
Pavlov. Cond. latency score	1.2	1.5	3.2	0.8	-0.8	-1.8
Pavlov. Cond. lever contacts	0.4	0.4	1.3	0.1	-0.2	-1.1
Pavlov. Cond. magazine entry number	1.7	2.1	4.2	-1.1	1.1	2.0
Pavlov. Cond. intertrial magazine entries	0.5	0.6	0.8	0.9	-0.9	-0.4
Pavlov. Cond. lever-magazine prob. diff.	2.2	2.7	5.2	1.2	-1.2	-2.3
Pavlov. Cond. response bias	1.1	1.3	3.2	0.6	-0.6	-1.8
Pavlov. Cond. lever latency	4.5	6.1	6.9	2.6	-2.6	-2.2
Pavlov. Cond. magazine entry latency	2.0	2.3	2.9	-1.7	1.7	1.0
Pavlov. Cond. change in total contacts	7.9	10.8	11.5	-3.4	3.4	3.1
Pavlov. Cond. index score	4.3	5.6	6.5	-2.5	2.5	1.9
Pavlov. Cond. latency score	4.0	4.9	5.8	-2.4	2.4	1.8
Pavlov. Cond. lever contacts	4.2	5.7	6.2	-2.5	2.5	2.2
Pavlov. Cond. magazine entry number	3.5	4.3	4.9	2.2	-2.2	-1.8
Pavlov. Cond. intertrial magazine entries	0.7	0.9	1.1	1.0	-1.0	-0.7
Pavlov. Cond. lever-magazine prob. diff.	4.3	5.4	6.4	-2.5	2.5	1.9
Pavlov. Cond. response bias	4.7	6.5	7.1	-2.7	2.7	2.3
Time in closed arm before self-admin	2.9	3.2	3.6	1.9	-1.9	-1.6
Time in closed arm after self-admin	0.0	0.0	0.1	-0.0	0.0	0.3
Time in open arm before self-admin	4.3	4.7	5.4	-2.3	2.3	1.8
Time in open arm after self-admin	0.9	1.0	1.5	-1.2	1.2	0.3
Bone: periosteal estimation	1.9	4.0	4.5	-2.1	2.1	1.8
Bone: periosteal perimeter	1.0	1.7	2.1	-1.5	1.5	1.0
Bone: post-yield work	1.9	2.6	3.1	-1.5	1.5	1.8
Progressive ratio test 1 active lever presses	0.2	0.2	0.3	-0.5	0.5	0.4
Progressive ratio test 1 breakpoint	0.5	0.5	0.6	-0.8	0.8	0.6
Progressive ratio test 1 inactive lever presses	0.1	0.2	0.2	-0.5	0.5	0.0
Progressive ratio test 2 active lever presses	0.1	0.1	0.2	0.1	-0.1	-0.4
Progressive ratio test 2 breakpoint	0.1	0.1	0.3	0.2	-0.2	-0.6
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.2	-0.5	0.5	0.2
Incentive Sensitization - Responses	0.1	0.1	0.2	0.3	-0.3	-0.5
Incentive Sensitization - Breakpoint	0.1	0.1	0.2	0.2	-0.2	-0.4
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	-0.4	0.4	0.6
Progressive ratio	0.2	0.2	0.5	0.1	-0.1	-0.7
Food seeking constrained by brief footshock	2.2	2.8	3.6	-1.9	1.9	1.0
Seeking ratio, punishment vs. effort	0.6	0.7	0.9	-0.8	0.8	0.9
Retroperitoneal fat weight	0.9	2.9	3.7	1.9	-1.9	-1.2
Reaction time number correct	0.0	0.0	0.1	-0.1	0.1	0.3
Reaction time mean minus median	0.6	0.8	0.9	-0.9	0.9	0.9
Reaction time mean minus median AUC	1.3	1.7	1.7	-1.3	1.3	1.3
Reaction time num false alarms	0.7	1.0	1.1	1.1	-1.1	-0.9
Reaction time num false alarms AUC	1.0	1.4	1.5	1.2	-1.2	-1.1
Reaction time trials correct on left	0.0	0.0	0.1	-0.1	0.1	0.3
Reaction time trials on left	0.0	0.0	0.1	-0.1	0.1	0.3
Reaction time mean	0.2	0.3	0.4	-0.5	0.6	0.6
Reaction time mean AUC	0.1	0.1	0.2	-0.4	0.4	0.3
Median of all reaction times	0.0	0.1	0.1	-0.2	0.2	0.2
Reaction time omissions	0.0	0.0	0.0	-0.0	0.0	-0.1
Reaction time false alarm rate	0.7	1.0	1.1	1.0	-1.0	-1.0
Reaction time premature initiation rate	0.2	0.2	0.7	-0.0	-0.0	-0.8
Reaction time premature initiations	0.1	0.1	0.4	-0.0	0.0	-0.6
Std. dev. reaction times	0.9	1.3	1.6	-1.1	1.1	1.3
Reaction time trials completed	0.0	0.0	0.1	-0.1	0.1	0.3
Reaction time trials AUC	0.0	0.0	0.1	-0.0	0.0	0.2
Run reversals in cocaine runway, females	1.2	1.1	1.8	-0.9	0.9	1.3
Run reversals in cocaine runway, males	0.2	0.2	0.4	0.2	-0.2	-0.6
Latency to leave start box in cocaine runway	0.3	0.3	0.6	-0.4	0.4	0.8
Latency to leave start box in cocaine runway, F	0.2	0.2	0.5	-0.1	0.1	0.7
Latency to leave start box in cocaine runway, M	0.0	0.0	0.1	-0.2	0.2	0.1
Std. dev. time between licks in bursts	0.2	0.3	0.8	-0.2	0.1	-0.9
Total sessions with >9 infusions	1.3	1.5	1.6	1.2	-1.2	-1.3
Short access day 1 total inactive lever presses	0.0	0.0	0.1	-0.1	0.1	0.3
Short access day 10 total inactive lever presses	1.5	1.7	1.9	-1.2	1.2	1.4
Short access day 1 total infusions	0.2	0.2	0.2	0.4	-0.4	-0.4
Short access day 10 total infusions	0.5	0.6	0.8	0.7	-0.7	-0.9
Short access total infusions	1.2	1.3	1.5	1.1	-1.1	-1.2
Short access day 1 locomotion	0.2	0.3	0.3	0.5	-0.5	-0.5
Short access day 10 total locomotion	0.2	0.2	0.4	-0.6	0.6	0.1
Short access total locomotion	1.3	1.4	1.7	1.1	-1.1	-1.3
One hour access (0.3 mA shock)	0.4	0.4	0.7	-0.8	0.8	-0.0
Compulsive drug intake	0.0	0.0	0.0	-0.2	0.2	-0.1
One hour access (shock baseline)	0.1	0.1	0.4	0.1	-0.1	-0.6
Social response proportion	2.4	2.6	3.4	-1.5	1.5	1.8
Social responses	0.4	0.5	0.7	-0.8	0.8	0.4
Social time	3.1	4.2	4.7	-2.0	2.0	2.2
Soleus weight	0.1	0.2	0.2	0.4	-0.4	-0.5
Bone: stiffness	1.7	2.7	3.7	-1.5	1.5	1.9
Tibialis anterior weight	0.0	0.1	0.3	-0.0	0.0	0.6
Time to tail flick, vehicle, before self-admin	1.0	1.1	1.2	1.1	-1.1	-0.9
Time to tail flick, vehicle, after self-admin	0.3	0.3	0.9	0.2	-0.2	-0.9
Time to tail flick, test, before self-admin	0.2	0.1	0.2	0.5	-0.4	0.2
Time to tail flick, test, after self-admin	0.0	0.0	0.0	-0.0	0.0	0.2
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.6	-0.8	0.7	0.1
Delta time to tail flick, test, before/after SA	0.3	0.3	0.7	0.3	-0.3	-0.8
Tibia length	3.5	10.0	11.7	-3.0	3.0	3.4
Ambulatory time before self-admin	0.1	0.1	0.1	0.2	-0.2	-0.3
Ambulatory time after self-admin	7.1	7.8	8.4	-2.9	2.9	2.6
Bone: tissue strength	3.9	3.8	4.4	-1.9	1.8	2.1
Total heroin consumption	0.2	0.3	0.4	-0.5	0.5	0.6
Bone: trabecular number	1.5	2.4	2.6	-1.6	1.6	1.4
Bone: trabecular spacing	0.1	0.1	0.1	-0.3	0.3	-0.3
Bone: trabecular thickness	0.0	0.0	0.1	0.0	-0.0	0.3
Bone: trabecular tissue density	1.9	2.7	2.9	1.7	-1.7	-1.6
Water consumed over 24 hours	0.6	0.7	0.8	-0.8	0.8	0.9
Number of responses in last shaping day	0.1	0.1	0.1	0.4	-0.4	-0.3