LOC120096359

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression LOC120096359 0.13 0.07 3.5e-12 0.07 0.09 0.09 0.09 1.3e-08 2.5e-10 1.1e-09 1.6e-10
2 BLA gene expression LOC120096359 0.09 0.06 6.2e-04 0.07 0.03 0.05 0.05 8.4e-05 6.7e-03 1.1e-03 1.4e-03
3 PL gene expression LOC120096359 0.2 0.09 0.0e+00 0.19 0.22 0.22 0.22 3.6e-20 3.6e-24 2.0e-23 4.5e-23
4 OFC gene expression LOC120096359 0.39 0.16 3.2e-06 0.15 0.22 0.22 0.23 1.8e-04 6.3e-06 6.0e-06 4.3e-06
5 NAcc gene expression LOC120096359 0.41 0.15 0.0e+00 0.26 0.29 0.3 0.3 6.5e-39 4.4e-45 3.0e-45 3.1e-45
6 IC gene expression LOC120096359 0.19 0.09 6.7e-06 0.09 0.1 0.1 0.09 1.9e-04 8.8e-05 6.1e-05 1.6e-04
7 pVTA gene expression LOC120096359 0.25 0.12 2.4e-12 0.11 0.15 0.14 0.16 4.5e-09 1.9e-12 9.3e-12 6.1e-13
8 Brain gene expression LOC120096359 0.17 0.08 5.6e-17 0.19 0.18 0.17 0.18 2.1e-17 1.0e-16 8.5e-16 1.0e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.50.91.6-0.60.1-1.0-1.2-1.3-0.7-1.2-0.9
Area under the delay curve0.10.10.2-0.20.1-0.2-0.3-0.40.0-0.3-0.3
BMI with tail0.10.30.5-0.6-0.1-0.6-0.6-0.5-0.2-0.7-0.5
BMI without tail0.92.94.5-2.1-1.2-1.9-1.8-1.5-0.7-1.8-2.1
Body weight2.912.518.8-4.1-4.3-3.9-3.6-2.9-1.7-3.3-3.8
Weight adjusted by age2.33.44.4-1.3-1.8-2.0-2.1-1.9-1.4-2.1-2.0
Bone surface0.51.01.6-0.3-0.9-1.2-1.2-1.3-1.1-1.1-0.7
Bone volume0.50.81.3-0.9-0.6-1.1-1.1-1.1-0.5-1.0-0.9
Breakpoint value in progressive ratio session0.70.82.8-1.0-1.7-0.9-0.6-0.4-0.5-0.5-0.9
Number of licking bursts0.71.12.40.3-0.1-1.1-1.2-1.5-1.4-1.3-0.2
Context. condit. distance diff. score1.62.02.8-0.9-0.3-1.5-1.7-1.7-1.3-1.6-1.6
Locomotion velocity, session 10.70.71.70.9-1.3-0.7-0.1-0.7-1.3-0.50.6
Locomotion distance, session 11.92.43.7-0.4-1.3-1.9-1.6-1.9-1.8-1.8-0.9
Locomotion velocity, session 20.20.30.5-0.2-0.4-0.7-0.5-0.7-0.6-0.60.4
Locomotion distance, session 20.00.10.2-0.1-0.5-0.3-0.0-0.2-0.2-0.10.3
Locomotion velocity, session 31.01.12.5-1.6-1.5-1.0-0.7-0.50.1-0.7-1.4
Locomotion distance, session 30.70.72.0-1.10.40.50.60.81.40.6-1.0
Stereotopy head waving bouts, day 31.11.33.61.4-1.5-0.8-0.5-1.1-1.9-0.80.4
Stereotopy head waving duration, day 31.61.95.11.5-1.5-1.1-0.9-1.6-2.3-1.20.4
Locomotion velocity, session 71.61.73.9-0.80.11.21.51.82.01.5-0.1
Locomotion distance, session 72.22.85.4-0.41.61.81.92.12.31.8-0.3
Stereotopy head waving bouts, day 72.22.55.10.2-2.3-1.6-1.4-1.7-2.1-1.6-0.3
Stereotopy head waving duration, day 72.73.36.80.5-2.0-1.9-1.8-2.2-2.6-1.9-0.4
Locomotion velocity, session 81.01.23.00.5-0.0-1.1-1.1-1.5-1.7-1.3-0.1
Locomotion distance, session 81.31.93.1-0.6-0.7-1.7-1.5-1.7-1.5-1.6-1.3
Degree of sensitization distance0.50.51.20.81.10.70.60.60.10.60.9
Degree of sensitization stereotypy0.60.61.3-0.1-1.1-0.8-0.8-0.8-0.9-0.80.1
Conditioned locomotion0.60.62.11.50.90.60.50.3-0.30.41.1
Cocaine response after cond. corrected0.20.20.91.00.10.10.2-0.2-0.60.00.6
Cocaine response after cond. not corrected0.60.72.01.1-0.0-0.5-0.4-1.1-1.4-0.70.3
Cocaine response before conditioning0.91.11.9-0.4-0.2-1.2-1.2-1.4-1.1-1.2-1.0
Saline control response0.70.91.9-1.11.4-0.6-0.9-0.80.1-0.8-1.4
Bone: connectivity density1.62.54.5-0.2-0.3-1.7-1.8-2.1-1.9-1.9-1.3
Bone: cortical apparent density0.30.40.7-0.10.40.70.80.80.80.8-0.1
Bone: cortical area1.21.82.6-1.4-1.3-1.6-1.4-1.3-0.8-1.4-1.3
Bone: cortical porosity0.50.61.30.80.4-0.5-0.8-1.0-1.1-0.8-0.3
Bone: cortical porosity0.40.50.90.80.6-0.4-0.7-0.8-0.9-0.7-0.1
Bone: cortical thickness0.61.01.4-0.3-0.9-1.2-1.1-1.2-1.1-1.1-0.7
Bone: cortical thickness2.12.53.6-0.7-1.2-1.9-1.9-1.8-1.7-1.9-1.0
Bone: cortical tissue density0.40.50.9-0.10.40.80.90.90.80.90.0
Condit. Reinf. active minus inactive responses0.20.30.7-0.8-0.10.10.30.40.70.3-0.8
Condit. Reinf. active-inactive response ratio0.20.20.60.30.80.50.60.40.50.40.1
Condit. Reinf. active responses0.70.93.9-2.0-0.6-0.5-0.40.10.8-0.2-1.3
Condit. Reinf. inactive responses1.21.53.9-2.0-1.1-1.3-1.3-0.9-0.1-1.0-1.3
Incentive salience index mean0.50.62.8-1.7-0.2-0.2-0.20.30.9-0.0-1.0
Condit. Reinf. lever presses1.01.46.1-2.5-0.6-0.9-0.9-0.20.7-0.7-1.3
Condit. Reinf. active minus inactive responses0.30.41.8-0.21.30.50.20.40.70.40.2
Condit. Reinf. active-inactive response ratio0.81.01.60.91.31.00.90.90.60.91.2
Condit. Reinf. active responses0.30.41.1-0.90.70.40.10.51.10.40.0
Condit. Reinf. inactive responses1.21.65.5-2.3-1.0-1.0-1.1-0.50.5-0.8-1.7
Condit. Reinf. lever presses0.30.41.5-1.2-0.0-0.3-0.60.00.6-0.3-0.8
Condit. Reinf. lever reinforcers received0.20.30.9-0.80.50.30.10.51.00.3-0.1
Conditioned reinforcement - actives0.61.01.6-0.2-0.8-1.2-1.1-1.3-1.2-1.2-0.8
Conditioned reinforcement - inactives1.72.53.4-0.8-1.8-1.8-1.7-1.7-1.6-1.7-1.3
Conditioned locomotion3.03.95.3-0.7-1.7-2.3-2.1-2.3-2.1-2.2-1.7
Patch foraging indifference point 0 sec1.52.74.4-0.3-1.0-1.9-1.8-2.1-1.9-2.0-1.2
Patch foraging indifference point AUC1.01.42.30.70.91.51.51.41.21.40.4
Delay disc. indifference point, 0s delay0.30.31.30.1-1.1-0.5-0.3-0.5-0.5-0.4-0.1
Delay disc. indifference point, 16s delay0.20.20.4-0.20.5-0.4-0.4-0.6-0.3-0.5-0.4
Delay disc. indifference point, 2s delay0.20.30.5-0.30.4-0.5-0.6-0.7-0.2-0.6-0.6
Delay disc. indifference point, 24s delay0.20.21.0-0.41.0-0.0-0.2-0.40.4-0.2-0.4
Delay disc. indifference point, 4s delay0.40.41.3-1.1-0.8-0.4-0.4-0.20.4-0.3-0.7
Delay disc. indifference point, 8s delay0.30.30.70.80.40.60.50.30.20.40.8
Indifference point function ln k1.22.04.40.5-1.4-1.5-1.3-1.8-2.1-1.50.1
Indifference point function log k1.22.04.40.5-1.4-1.5-1.3-1.8-2.1-1.50.1
Patch foraging total patch changes 0 sec1.52.74.5-0.3-0.9-1.9-1.9-2.1-1.9-2.0-1.3
Patch foraging total patch changes 12 sec0.70.91.2-0.6-0.7-1.1-0.9-1.0-0.8-1.0-1.1
Patch foraging total patch changes 18 sec0.20.20.9-0.5-0.7-0.3-0.2-0.1-0.0-0.2-0.9
Patch foraging total patch changes 24 sec0.20.31.2-1.1-0.0-0.3-0.4-0.10.4-0.2-0.8
Patch foraging total patch changes 6 sec0.30.41.3-0.8-0.5-0.5-0.6-0.4-0.1-0.6-1.1
Patch foraging time to switch 0 sec0.40.72.4-1.2-1.5-0.8-0.8-0.3-0.2-0.6-0.7
Patch foraging water rate 0 sec0.40.92.31.51.5-0.2-0.3-0.9-1.2-0.50.3
Patch foraging water rate 12 sec0.61.22.81.31.51.11.00.70.20.91.7
Patch foraging water rate 18 sec0.10.10.40.60.10.1-0.0-0.0-0.5-0.00.6
Patch foraging water rate 24 sec0.20.30.80.9-0.1-0.00.0-0.2-0.7-0.10.9
Patch foraging water rate 6 sec0.20.30.80.60.9-0.4-0.3-0.8-0.7-0.5-0.0
Seeking ratio, delayed vs. immediate footshock0.30.41.1-0.71.10.3-0.00.40.90.2-0.2
Distance traveled before self-admin3.74.88.1-0.4-1.1-2.5-2.5-2.9-2.6-2.6-1.9
Distance traveled after self-admin2.12.64.7-0.2-1.4-1.9-1.7-1.9-2.2-1.8-1.1
Extensor digitorum longus weight0.31.02.5-1.3-0.70.60.61.41.60.90.5
Bone: elastic displacement0.91.02.81.3-0.2-0.7-0.8-1.2-1.7-1.0-0.5
Bone: elastic work0.81.02.60.9-0.6-0.9-0.9-1.2-1.6-1.1-0.4
Bone: endosteal estimation0.00.10.4-0.4-0.6-0.00.20.20.40.2-0.1
Bone: endosteal perimeter0.20.41.6-1.3-0.6-0.4-0.20.10.7-0.1-0.8
Epididymis fat weight1.03.34.8-0.2-1.7-2.0-2.2-2.2-2.2-2.1-0.9
Delta time in closed arm before/after self-admin0.40.40.60.30.10.60.80.70.40.80.8
Delta time in open arm before/after self-admin1.01.03.8-2.0-0.1-0.4-0.50.01.1-0.3-1.4
Diff in mean of infusions in LGA sessions0.60.71.0-0.60.1-1.0-1.0-0.9-0.8-1.0-1.0
Delay discount exponential model param0.10.10.20.3-0.20.30.40.5-0.00.40.4
Extinction: sum of active levers before priming2.32.64.9-2.2-1.6-1.8-1.5-1.1-0.5-1.3-2.2
Active lever presses in extinction session 64.64.68.9-1.9-3.0-2.4-2.1-1.6-1.7-2.0-2.3
Bone: final force0.71.23.0-0.3-1.7-1.2-1.1-1.0-1.1-1.0-0.5
Bone: final moment0.71.13.0-0.6-1.7-1.2-1.0-0.9-0.9-1.0-0.5
Food consumed during 24 hour testing period0.50.61.50.4-1.2-0.8-0.4-0.9-1.1-0.60.4
Glucose0.30.42.11.50.50.20.2-0.2-0.60.00.7
Heart weight0.50.82.3-1.5-0.6-0.9-0.9-0.6-0.1-0.8-1.0
Delay discount hyperbolic model param0.20.20.40.5-0.10.40.50.6-0.00.50.6
Intermittent access intake day 1-15 change0.81.75.22.3-0.21.11.20.8-0.41.02.0
Intermittent access intake escalation0.81.76.02.50.11.01.10.6-0.60.82.0
Intermittent access intake escalation 21.01.14.12.0-0.10.80.90.5-0.60.61.6
Intermitt. access day 1 inactive lever presses0.00.10.4-0.3-0.60.10.30.40.40.3-0.2
Intermitt. access day 15 inactive lever presses0.10.21.0-1.0-0.7-0.1-0.10.30.50.1-0.4
Intermitt. access escalation Index0.40.51.0-0.20.50.70.80.91.00.80.6
Intermittent access day 1 total infusions1.32.12.6-1.5-1.4-1.6-1.5-1.4-1.0-1.4-1.5
Intermittent access day 15 total infusions0.60.92.51.3-0.9-0.5-0.4-0.8-1.6-0.60.7
Intermittent access terminal intake (last 3 days)0.40.51.41.0-1.2-0.00.3-0.1-0.80.10.9
Intermittent access total infusions0.60.71.70.3-0.8-0.8-0.7-1.0-1.3-0.8-0.0
Intermittent access day 1 locomotion2.53.24.1-1.4-2.0-2.0-1.9-1.8-1.5-1.8-1.8
Intermittent access day 15 total locomotion1.62.95.1-0.0-2.3-1.8-1.6-1.9-2.1-1.7-1.0
Intermittent access total locomotion2.53.04.1-0.7-1.6-2.0-1.9-2.0-1.8-1.9-1.6
Intermittent access standard deviation0.30.61.20.6-0.50.70.80.80.30.81.1
Left kidney weight1.67.612.5-2.3-3.5-3.1-2.8-2.6-2.0-2.8-2.7
Right kidney weight2.09.020.4-2.1-4.5-3.3-2.9-2.7-2.4-2.9-2.4
Cocaine induced anxiety0.50.72.4-1.5-1.00.10.30.71.20.5-0.6
Post-drug Anxiety0.30.40.7-0.2-0.50.50.70.80.70.80.3
Baseline Anxiety1.72.08.52.91.20.80.7-0.1-1.10.41.9
Tail length2.49.216.5-4.1-3.4-3.2-3.0-2.2-0.9-2.6-3.8
Length with tail3.716.229.1-4.8-5.4-4.4-4.0-3.1-1.9-3.5-4.2
Length without tail2.16.714.7-2.1-3.8-2.9-2.7-2.3-2.0-2.4-2.0
Times rat made contact with spout0.20.30.40.1-0.6-0.5-0.6-0.6-0.6-0.5-0.3
Lifetime Intake0.81.02.00.0-1.0-1.1-1.0-1.2-1.4-1.0-0.3
Liver weight, left0.50.91.3-0.8-1.2-1.1-1.1-0.9-0.8-1.0-0.4
Liver weight, right0.81.43.00.4-0.8-1.2-1.3-1.5-1.7-1.3-0.2
Locomotor activity0.40.62.70.7-1.6-0.5-0.1-0.4-1.1-0.20.0
Locomotor testing distance0.10.20.90.2-0.9-0.3-0.0-0.1-0.5-0.10.3
Locomotor testing rearing0.10.20.80.10.90.40.60.40.40.50.3
Locomotion in novel chamber0.30.30.60.00.00.70.60.70.80.70.5
Locomotion in novel chamber post-restriction0.10.10.70.10.80.0-0.3-0.1-0.2-0.20.1
Fecal boli incidents, locomotor time 10.00.10.10.10.40.30.10.30.10.20.2
Change in fecal boli incidents, locomotor task0.10.10.20.5-0.50.10.10.0-0.3-0.00.4
Time >=10cm from walls, locomotor time 10.10.10.30.4-0.2-0.2-0.0-0.3-0.5-0.10.2
Bouts of movement, locomotor time 10.30.31.11.00.30.20.2-0.4-0.50.10.9
Total resting periods, locomotor time 10.20.20.70.80.40.30.4-0.2-0.10.30.9
Rest time, locomotor task time 10.50.61.81.20.20.70.80.20.00.71.4
Distance moved, locomotor task time 10.50.82.2-0.7-1.5-1.0-0.7-0.6-0.7-0.7-0.7
Vertical activity count, locomotor time 10.20.50.80.00.2-0.8-0.8-0.8-0.9-0.9-0.4
Time >=10cm from walls, locomotor time 20.40.51.9-1.1-1.4-0.5-0.2-0.00.2-0.1-1.0
Bouts of movement, locomotor time 20.10.20.90.61.00.20.1-0.1-0.0-0.00.3
Total resting periods, locomotor time 20.00.10.40.40.60.10.0-0.1-0.1-0.10.2
Rest time, locomotor task time 21.21.52.61.40.71.31.41.10.41.31.6
Distance moved, locomotor task time 22.32.75.1-1.2-2.3-1.9-1.6-1.5-1.3-1.6-1.5
Vertical activity count, locomotor time 20.50.71.0-0.1-0.6-0.9-0.9-1.0-0.9-1.0-0.8
Light reinforcement 10.20.51.81.4-0.2-0.2-0.4-0.6-1.2-0.40.4
Light reinforcement 20.81.33.51.8-0.9-0.5-0.6-1.0-1.9-0.70.8
Bone: marrow area0.00.10.3-0.3-0.50.00.20.20.30.2-0.0
Bone: maximum diameter0.30.61.3-1.1-0.9-0.9-0.7-0.6-0.1-0.7-0.7
Bone: maximum force1.42.44.3-0.1-2.1-1.7-1.5-1.7-1.9-1.6-0.8
Bone: maximum moment1.32.34.6-0.4-2.1-1.8-1.5-1.6-1.7-1.6-0.9
Mean time between licks in bursts0.30.71.5-0.40.10.80.91.21.20.90.9
Mean num. licks in bursts0.50.71.7-0.3-0.10.90.91.31.11.0-0.0
Cd content in liver6.67.413.7-3.6-2.0-2.9-2.9-2.1-0.8-2.6-3.7
Co content in liver1.11.33.11.0-0.5-1.1-1.1-1.5-1.8-1.2-0.2
Cu content in liver3.94.67.41.91.92.42.22.11.52.22.7
Fe content in liver3.13.85.01.41.92.22.22.01.72.21.8
K content in liver1.01.01.31.10.81.11.11.00.61.11.0
Mg content in liver0.70.71.40.3-0.1-0.9-1.0-1.1-1.2-1.0-0.1
Mn content in liver0.30.30.5-0.60.7-0.5-0.7-0.4-0.1-0.5-0.5
Na content in liver2.83.04.11.21.42.02.01.71.32.02.0
Rb content in liver1.61.92.91.01.21.51.41.51.11.41.7
Se content in liver0.40.51.00.2-0.4-0.8-0.7-1.0-1.0-0.80.0
Sr content in liver0.80.72.3-1.00.50.60.51.01.50.70.3
Zn content in liver7.17.911.6-0.7-2.0-3.2-3.3-3.4-3.2-3.3-2.0
Bone: minimum diameter0.40.83.4-1.80.1-0.1-0.00.51.30.1-0.9
Time in familiar zone, hab. session 11.31.32.6-0.40.41.11.41.41.61.40.2
Time in novel zone, hab. session 11.41.42.1-0.9-1.5-1.3-1.4-1.1-1.0-1.3-0.8
Total zone transitions, hab. session 11.21.74.3-0.6-2.1-1.5-1.1-1.3-1.2-1.3-0.5
Total locomotion distance, hab. session 11.11.65.40.2-2.3-1.3-0.9-1.2-1.6-1.00.0
Locomotion velocity, hab. session 11.21.73.50.5-1.8-1.3-1.1-1.4-1.9-1.2-0.1
Time in familiar zone, hab. session 20.10.10.7-0.5-0.3-0.3-0.0-0.10.0-0.2-0.8
Time in novel zone, hab. session 20.10.10.5-0.7-0.5-0.3-0.4-0.10.1-0.3-0.2
Total zone transitions, hab. session 21.41.82.7-1.2-1.4-1.6-1.4-1.4-0.9-1.4-1.2
Total locomotion distance, hab. session 21.01.32.4-0.7-1.6-1.4-1.0-1.2-1.0-1.2-0.8
Locomotion velocity, hab. session 20.81.11.6-0.4-1.3-1.3-1.0-1.3-1.1-1.1-0.6
Novel to familiar place preference ratio0.10.10.3-0.10.1-0.3-0.5-0.3-0.3-0.4-0.2
Novelty place preference0.20.20.5-0.3-0.1-0.5-0.7-0.4-0.5-0.6-0.3
Time in novel zone, NPP test0.20.20.4-0.4-0.2-0.4-0.7-0.4-0.4-0.5-0.3
Total zone transitions, NPP test2.23.25.2-1.0-1.7-2.3-2.0-2.1-1.9-2.1-0.7
Total locomotion distance, NPP test1.21.62.6-0.6-1.4-1.6-1.3-1.4-1.3-1.4-0.4
Locomotion velocity, NPP test1.11.62.6-0.5-1.4-1.6-1.2-1.5-1.4-1.5-0.5
Intraocular pressure0.10.20.80.9-0.3-0.1-0.1-0.4-0.7-0.2-0.1
Delta distance traveled before/after self-admin0.30.30.8-0.2-0.40.50.60.90.70.70.5
Delta ambulatory time before/after self-admin0.20.30.50.20.30.60.50.70.40.50.7
Parametrial fat weight0.20.41.0-0.9-1.00.10.30.70.70.4-0.1
Pavlov. Cond. lever latency1.62.07.62.80.31.31.60.7-0.31.31.5
Pavlov. Cond. magazine entry latency1.41.89.4-3.1-1.2-0.8-0.80.11.2-0.4-1.0
Pavlov. Cond. change in total contacts1.92.07.4-2.7-0.0-1.1-1.3-0.50.6-1.0-2.0
Pavlov. Cond. index score1.11.47.8-2.8-0.1-0.6-0.80.11.2-0.4-1.0
Pavlov. Cond. latency score1.31.68.6-2.9-0.1-0.7-1.0-0.01.1-0.6-1.2
Pavlov. Cond. lever contacts0.91.04.5-2.1-0.2-0.8-1.1-0.40.4-0.9-0.9
Pavlov. Cond. magazine entry number1.21.68.62.91.00.50.4-0.5-1.40.10.7
Pavlov. Cond. intertrial magazine entries0.50.61.20.80.4-0.5-0.5-1.0-1.1-0.5-1.1
Pavlov. Cond. lever-magazine prob. diff.1.11.47.4-2.7-0.5-0.8-0.9-0.10.9-0.6-0.9
Pavlov. Cond. response bias1.31.68.0-2.8-1.1-0.8-0.90.00.9-0.5-0.9
Pavlov. Cond. lever latency0.81.12.31.50.61.01.20.70.10.91.4
Pavlov. Cond. magazine entry latency1.31.52.7-1.2-0.5-1.3-1.7-1.1-0.7-1.3-1.6
Pavlov. Cond. change in total contacts0.20.30.9-0.00.90.60.20.70.60.50.4
Pavlov. Cond. index score1.11.52.9-1.5-0.6-1.3-1.6-1.0-0.5-1.2-1.7
Pavlov. Cond. latency score1.01.42.4-1.5-0.4-1.2-1.6-0.9-0.3-1.2-1.5
Pavlov. Cond. lever contacts0.60.81.7-1.3-0.6-0.9-1.0-0.6-0.2-0.8-1.2
Pavlov. Cond. magazine entry number0.70.81.80.80.00.91.40.70.61.01.3
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.4-0.40.30.40.30.70.40.2
Pavlov. Cond. lever-magazine prob. diff.1.01.32.6-1.3-0.4-1.1-1.5-0.9-0.5-1.2-1.6
Pavlov. Cond. response bias1.01.42.5-1.6-0.9-1.2-1.4-0.9-0.4-1.1-1.6
Time in closed arm before self-admin0.10.10.20.40.3-0.1-0.4-0.4-0.4-0.5-0.3
Time in closed arm after self-admin0.50.62.41.6-0.20.30.50.1-0.80.31.0
Time in open arm before self-admin0.30.40.9-0.6-1.0-0.6-0.6-0.4-0.5-0.4-0.4
Time in open arm after self-admin1.01.15.0-2.2-0.4-0.3-0.40.31.3-0.1-1.3
Bone: periosteal estimation0.40.92.0-1.2-1.4-1.0-0.8-0.7-0.3-0.8-0.8
Bone: periosteal perimeter0.61.01.7-1.3-1.2-1.1-1.0-0.8-0.2-0.9-0.9
Bone: post-yield work0.10.10.40.6-0.0-0.10.0-0.3-0.4-0.10.1
Progressive ratio test 1 active lever presses0.50.72.0-1.2-1.4-0.8-0.5-0.4-0.2-0.4-0.9
Progressive ratio test 1 breakpoint0.50.62.1-1.1-1.4-0.7-0.5-0.4-0.2-0.4-0.8
Progressive ratio test 1 inactive lever presses0.60.83.0-1.7-1.5-0.6-0.50.10.4-0.2-0.8
Progressive ratio test 2 active lever presses0.10.20.8-0.4-0.9-0.4-0.2-0.2-0.2-0.2-0.1
Progressive ratio test 2 breakpoint0.10.10.8-0.3-0.9-0.3-0.1-0.2-0.2-0.1-0.1
Progressive ratio test 2 inactive lever presses1.62.75.0-0.9-2.2-1.8-1.7-1.6-1.6-1.7-1.2
Incentive Sensitization - Responses0.10.10.6-0.1-0.8-0.3-0.2-0.2-0.4-0.20.0
Incentive Sensitization - Breakpoint0.10.10.6-0.1-0.8-0.2-0.1-0.1-0.3-0.10.1
Sum of active levers in priming session hrs 5-64.13.85.9-2.1-2.4-2.1-1.9-1.5-1.1-1.7-2.4
Progressive ratio3.96.212.10.40.3-2.6-2.8-3.5-3.0-3.0-2.1
Food seeking constrained by brief footshock0.60.71.10.10.90.90.81.01.10.80.5
Seeking ratio, punishment vs. effort3.44.99.7-0.4-0.12.42.43.12.82.61.8
Retroperitoneal fat weight1.66.78.8-2.1-2.8-3.0-2.9-2.5-2.0-2.7-2.6
Reaction time number correct0.30.52.5-0.71.60.3-0.20.20.80.00.0
Reaction time mean minus median0.30.72.91.7-0.4-0.0-0.0-0.6-1.3-0.10.7
Reaction time mean minus median AUC0.30.72.71.7-0.20.60.60.2-0.60.61.2
Reaction time num false alarms2.94.15.61.72.12.42.22.01.62.12.0
Reaction time num false alarms AUC2.23.44.71.81.72.22.01.81.31.92.0
Reaction time trials correct on left0.30.52.5-0.71.60.3-0.20.20.80.00.0
Reaction time trials on left0.20.42.5-0.61.60.3-0.20.10.7-0.0-0.0
Reaction time mean0.40.62.71.6-0.80.10.3-0.3-1.00.10.6
Reaction time mean AUC0.40.73.31.8-0.40.20.4-0.2-1.00.20.9
Median of all reaction times0.30.41.71.3-0.70.30.60.1-0.50.30.6
Reaction time omissions1.01.53.51.10.3-0.9-1.0-1.9-1.8-1.3-0.2
Reaction time false alarm rate1.41.93.01.60.51.51.71.40.71.51.4
Reaction time premature initiation rate0.40.61.2-0.0-1.10.50.70.90.50.81.0
Reaction time premature initiations0.30.51.2-0.1-0.10.70.70.90.80.81.1
Std. dev. reaction times0.81.54.51.9-1.2-0.6-0.4-1.2-2.1-0.70.4
Reaction time trials completed0.20.42.5-0.61.60.3-0.20.10.7-0.0-0.0
Reaction time trials AUC0.30.62.9-0.71.70.3-0.20.20.90.0-0.1
Run reversals in cocaine runway, females0.60.61.10.2-0.40.70.91.10.61.00.6
Run reversals in cocaine runway, males0.30.30.90.9-0.30.50.40.4-0.20.40.9
Latency to leave start box in cocaine runway1.21.43.01.11.71.31.11.00.81.01.1
Latency to leave start box in cocaine runway, F0.40.51.41.21.20.60.50.2-0.00.40.7
Latency to leave start box in cocaine runway, M1.11.01.40.30.81.21.01.21.11.10.9
Std. dev. time between licks in bursts0.20.20.7-0.8-0.10.10.10.40.80.1-0.6
Total sessions with >9 infusions1.21.42.1-1.2-1.4-1.4-1.2-1.1-0.8-1.1-1.2
Short access day 1 total inactive lever presses0.50.72.8-0.5-1.7-0.8-0.6-0.5-0.7-0.6-0.6
Short access day 10 total inactive lever presses0.30.71.9-1.2-0.10.50.41.11.40.6-0.5
Short access day 1 total infusions0.60.81.1-1.0-1.0-1.0-1.0-0.8-0.5-0.9-0.8
Short access day 10 total infusions0.91.21.7-0.8-0.8-1.3-1.2-1.3-1.0-1.2-0.9
Short access total infusions1.41.82.6-0.8-1.2-1.6-1.5-1.6-1.4-1.5-1.0
Short access day 1 locomotion2.22.73.9-1.6-0.7-1.8-2.0-1.7-1.0-1.8-2.0
Short access day 10 total locomotion0.00.00.10.2-0.4-0.1-0.0-0.1-0.1-0.0-0.1
Short access total locomotion1.11.31.8-0.6-1.0-1.3-1.3-1.3-1.1-1.2-1.2
One hour access (0.3 mA shock)0.20.30.6-0.6-0.8-0.6-0.6-0.3-0.4-0.5-0.4
Compulsive drug intake1.21.43.7-1.10.51.00.81.61.91.10.3
One hour access (shock baseline)0.60.92.60.7-0.9-0.9-0.7-1.2-1.6-0.9-0.1
Social response proportion0.10.21.00.11.00.20.20.10.30.0-0.2
Social responses0.40.52.5-0.51.60.10.0-0.00.6-0.2-0.9
Social time0.10.10.9-0.01.00.10.2-0.10.3-0.0-0.2
Soleus weight0.61.75.42.31.80.1-0.3-1.0-1.5-0.51.2
Bone: stiffness0.81.33.4-0.7-1.8-1.3-1.1-1.1-1.0-1.2-0.5
Tibialis anterior weight0.20.82.8-1.7-0.80.10.10.81.40.40.1
Time to tail flick, vehicle, before self-admin0.40.41.01.00.20.60.60.4-0.00.61.0
Time to tail flick, vehicle, after self-admin0.91.21.5-0.7-1.2-1.2-1.2-1.0-0.9-1.1-1.2
Time to tail flick, test, before self-admin1.71.85.00.9-1.1-1.3-1.1-1.6-2.2-1.3-0.3
Time to tail flick, test, after self-admin1.61.64.20.1-2.1-1.3-1.0-1.2-1.6-1.1-0.9
Delta time to tail flick, vehicle, before/after SA1.41.31.8-1.0-1.1-1.3-1.3-1.0-0.8-1.2-1.3
Delta time to tail flick, test, before/after SA0.30.30.8-0.7-0.9-0.4-0.3-0.20.1-0.3-0.8
Tibia length0.61.64.5-2.1-1.9-1.2-1.0-0.40.2-0.9-1.0
Ambulatory time before self-admin2.53.87.0-0.1-0.6-2.1-2.2-2.6-2.4-2.3-1.6
Ambulatory time after self-admin0.81.02.50.5-0.2-1.0-1.0-1.4-1.6-1.1-0.3
Bone: tissue strength0.80.84.10.8-2.00.20.60.4-0.30.50.9
Total heroin consumption3.94.56.6-2.2-2.3-2.4-2.2-1.8-1.3-2.1-2.6
Bone: trabecular number0.40.61.30.20.6-0.7-0.8-1.2-0.8-0.8-0.8
Bone: trabecular spacing0.60.74.3-1.1-2.1-0.5-0.30.20.0-0.1-0.2
Bone: trabecular thickness0.10.10.8-0.00.90.1-0.3-0.10.0-0.10.1
Bone: trabecular tissue density1.21.83.7-0.0-0.31.41.71.91.51.70.6
Water consumed over 24 hours0.20.30.60.3-0.3-0.6-0.6-0.8-0.8-0.6-0.1
Number of responses in last shaping day0.10.10.30.50.3-0.0-0.1-0.3-0.4-0.20.5