Hub : Genes

LOC120095284

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC120095284 0.21 0.15 8.8e-04 0.14 0.09 0.11 0.11 2.9e-04 3.3e-03 1.3e-03 1.7e-03
2 NAcc gene expression LOC120095284 0.03 0.02 1.1e-04 0.03 0.02 0.03 0.03 1.7e-05 1.4e-04 9.2e-05 8.2e-05
3 PL gene expression LOC120095284 0.03 0.04 2.1e-03 0.02 0.01 0.01 0.02 2.1e-03 3.5e-02 1.4e-02 2.7e-03
4 Brain gene expression LOC120095284 0.04 0.04 6.2e-03 0.02 0.02 0 0.02 9.9e-03 3.6e-03 1.2e-01 6.5e-03
5 Adipose gene expression LOC120095284 0.05 0.04 4.5e-07 0.04 0.03 0.04 0.01 1.3e-05 1.4e-04 1.5e-05 8.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5
Bone: apparent density1.83.03.81.71.51.71.8-2.0
Area under the delay curve0.40.40.8-0.2-0.9-0.8-0.60.5
BMI with tail19.667.774.48.38.68.58.3-7.3
BMI without tail1.54.65.52.32.22.32.1-1.7
Body weight1.35.76.52.12.52.52.5-2.2
Weight adjusted by age0.30.51.2-0.2-0.5-0.6-0.91.1
Bone surface0.71.21.61.01.01.31.1-1.1
Bone volume1.73.13.61.61.71.91.8-1.9
Breakpoint value in progressive ratio session2.22.73.4-1.8-1.5-1.4-1.81.6
Number of licking bursts0.20.31.2-1.1-0.4-0.3-0.40.2
Context. condit. distance diff. score0.60.71.11.01.01.00.7-0.5
Locomotion velocity, session 10.10.10.3-0.20.00.10.3-0.5
Locomotion distance, session 13.84.86.6-2.6-2.3-2.1-2.01.8
Locomotion velocity, session 21.31.51.9-1.0-1.4-1.3-1.21.1
Locomotion distance, session 24.86.68.8-3.0-2.6-2.5-2.52.2
Locomotion velocity, session 30.00.00.10.40.20.20.1-0.0
Locomotion distance, session 32.42.63.8-1.3-1.6-1.6-1.71.9
Stereotopy head waving bouts, day 34.65.46.01.92.52.42.4-2.4
Stereotopy head waving duration, day 33.64.34.81.82.12.12.1-2.2
Locomotion velocity, session 71.21.32.0-1.4-0.9-0.8-1.11.2
Locomotion distance, session 75.57.08.9-3.0-2.5-2.5-2.62.6
Stereotopy head waving bouts, day 70.30.30.40.40.60.60.6-0.6
Stereotopy head waving duration, day 70.20.20.30.50.50.50.5-0.5
Locomotion velocity, session 80.30.40.80.70.90.70.40.0
Locomotion distance, session 80.71.01.2-0.9-1.0-0.9-1.11.1
Degree of sensitization distance0.00.00.2-0.50.00.1-0.1-0.0
Degree of sensitization stereotypy0.10.10.2-0.5-0.3-0.3-0.30.3
Conditioned locomotion1.41.72.81.71.21.21.2-1.1
Cocaine response after cond. corrected5.76.87.32.62.72.62.6-2.4
Cocaine response after cond. not corrected3.03.54.22.01.81.81.9-1.8
Cocaine response before conditioning3.03.64.2-1.8-2.0-2.0-1.91.7
Saline control response0.10.20.3-0.0-0.4-0.4-0.50.6
Bone: connectivity density0.20.40.80.90.40.50.5-0.6
Bone: cortical apparent density5.98.111.6-2.7-2.5-2.5-3.03.4
Bone: cortical area0.30.41.01.00.50.70.6-0.4
Bone: cortical porosity0.20.20.30.50.20.10.6-0.5
Bone: cortical porosity0.30.30.60.70.40.40.7-0.6
Bone: cortical thickness0.10.20.50.4-0.1-0.0-0.30.7
Bone: cortical thickness1.21.42.2-0.6-1.5-1.5-1.10.9
Bone: cortical tissue density6.58.912.4-2.9-2.7-2.6-3.13.5
Condit. Reinf. active minus inactive responses0.50.51.4-1.2-0.6-0.6-0.60.4
Condit. Reinf. active-inactive response ratio0.10.10.30.10.10.10.4-0.6
Condit. Reinf. active responses0.60.71.9-1.4-0.7-0.7-0.70.3
Condit. Reinf. inactive responses0.70.91.5-1.2-0.8-0.9-0.80.8
Incentive salience index mean1.01.32.6-1.6-1.1-1.1-1.00.5
Condit. Reinf. lever presses1.42.03.4-1.9-1.4-1.4-1.40.9
Condit. Reinf. active minus inactive responses0.00.00.1-0.2-0.3-0.10.1-0.2
Condit. Reinf. active-inactive response ratio0.10.10.4-0.2-0.00.10.4-0.7
Condit. Reinf. active responses0.00.10.1-0.1-0.4-0.4-0.10.2
Condit. Reinf. inactive responses0.20.30.70.0-0.3-0.5-0.50.8
Condit. Reinf. lever presses0.91.31.9-0.4-1.4-1.4-1.01.2
Condit. Reinf. lever reinforcers received0.10.20.3-0.2-0.6-0.5-0.30.5
Conditioned reinforcement - actives0.20.41.1-1.0-0.3-0.40.3-0.7
Conditioned reinforcement - inactives0.00.00.0-0.00.10.10.1-0.2
Conditioned locomotion1.01.33.30.30.60.61.5-1.8
Patch foraging indifference point 0 sec0.61.22.21.50.80.71.1-1.2
Patch foraging indifference point AUC0.20.20.4-0.3-0.5-0.5-0.40.6
Delay disc. indifference point, 0s delay0.70.81.2-0.1-0.9-1.0-0.91.1
Delay disc. indifference point, 16s delay0.40.41.01.00.30.40.6-0.8
Delay disc. indifference point, 2s delay0.10.10.2-0.1-0.5-0.3-0.40.3
Delay disc. indifference point, 24s delay0.50.50.8-0.7-0.7-0.9-0.70.5
Delay disc. indifference point, 4s delay2.93.14.2-1.1-2.1-1.8-1.91.8
Delay disc. indifference point, 8s delay0.20.20.4-0.3-0.7-0.6-0.40.3
Indifference point function ln k0.00.00.1-0.1-0.2-0.2-0.10.0
Indifference point function log k0.00.00.1-0.1-0.2-0.2-0.10.0
Patch foraging total patch changes 0 sec0.71.22.21.50.80.81.1-1.2
Patch foraging total patch changes 12 sec0.00.10.2-0.0-0.3-0.40.1-0.1
Patch foraging total patch changes 18 sec0.81.22.41.50.70.61.2-1.2
Patch foraging total patch changes 24 sec0.50.91.91.00.60.50.9-1.4
Patch foraging total patch changes 6 sec0.30.50.80.90.50.40.8-0.7
Patch foraging time to switch 0 sec0.00.00.0-0.1-0.0-0.10.0-0.2
Patch foraging water rate 0 sec0.91.92.01.41.41.41.4-1.2
Patch foraging water rate 12 sec0.10.20.40.60.40.40.10.2
Patch foraging water rate 18 sec0.00.10.1-0.1-0.1-0.1-0.40.4
Patch foraging water rate 24 sec0.91.21.51.21.11.11.1-0.9
Patch foraging water rate 6 sec0.00.00.00.10.00.2-0.1-0.1
Seeking ratio, delayed vs. immediate footshock1.51.83.51.91.31.41.2-0.7
Distance traveled before self-admin0.60.81.5-1.2-1.0-1.1-0.60.2
Distance traveled after self-admin0.10.20.50.10.1-0.20.5-0.7
Extensor digitorum longus weight0.51.83.41.81.41.51.2-0.4
Bone: elastic displacement0.10.20.40.10.20.40.4-0.6
Bone: elastic work0.00.00.10.0-0.3-0.00.1-0.2
Bone: endosteal estimation0.20.51.10.50.40.50.8-1.1
Bone: endosteal perimeter0.61.32.21.01.01.01.2-1.5
Epididymis fat weight0.20.51.00.40.70.81.0-0.6
Delta time in closed arm before/after self-admin0.30.30.70.60.80.50.30.2
Delta time in open arm before/after self-admin1.61.51.9-1.0-1.4-1.0-1.41.4
Diff in mean of infusions in LGA sessions0.60.72.1-1.4-0.6-0.4-0.80.3
Delay discount exponential model param0.50.61.10.31.00.90.8-0.7
Extinction: sum of active levers before priming0.80.91.3-1.0-1.1-0.9-0.90.9
Active lever presses in extinction session 60.10.10.30.30.20.10.2-0.6
Bone: final force0.20.30.50.60.40.50.7-0.7
Bone: final moment0.30.40.50.70.50.70.7-0.7
Food consumed during 24 hour testing period1.52.12.6-1.6-1.4-1.3-1.51.4
Glucose1.72.73.31.61.81.71.7-1.4
Heart weight1.93.03.61.21.91.91.7-1.7
Delay discount hyperbolic model param0.50.51.00.31.00.80.7-0.7
Intermittent access intake day 1-15 change0.20.31.4-0.2-0.2-0.20.4-1.2
Intermittent access intake escalation0.10.31.2-0.1-0.1-0.10.3-1.1
Intermittent access intake escalation 20.91.03.30.40.50.41.0-1.8
Intermitt. access day 1 inactive lever presses0.00.00.1-0.20.0-0.1-0.10.3
Intermitt. access day 15 inactive lever presses0.91.83.21.51.10.91.2-1.8
Intermitt. access escalation Index0.20.20.8-0.9-0.4-0.4-0.2-0.1
Intermittent access day 1 total infusions0.10.10.4-0.20.0-0.0-0.10.6
Intermittent access day 15 total infusions0.00.00.1-0.3-0.2-0.3-0.0-0.1
Intermittent access terminal intake (last 3 days)0.10.10.30.00.20.10.4-0.5
Intermittent access total infusions0.00.00.10.10.20.20.20.0
Intermittent access day 1 locomotion0.10.20.4-0.7-0.3-0.3-0.30.4
Intermittent access day 15 total locomotion0.00.10.2-0.5-0.3-0.20.1-0.3
Intermittent access total locomotion0.10.10.3-0.2-0.1-0.10.4-0.5
Intermittent access standard deviation0.81.74.61.10.70.71.3-2.1
Left kidney weight0.00.10.10.20.30.30.2-0.2
Right kidney weight0.41.92.21.21.41.51.4-1.4
Cocaine induced anxiety0.20.20.40.20.60.50.6-0.5
Post-drug Anxiety0.20.30.7-0.8-0.5-0.5-0.30.1
Baseline Anxiety1.01.21.7-1.1-1.3-1.2-1.10.6
Tail length18.773.184.0-8.8-9.2-8.9-8.57.3
Length with tail6.930.134.1-5.8-5.8-5.6-5.44.7
Length without tail0.20.60.90.60.91.00.8-0.4
Times rat made contact with spout0.20.20.9-1.0-0.2-0.3-0.30.1
Lifetime Intake0.00.00.00.20.20.10.1-0.0
Liver weight, left0.00.00.10.10.30.30.10.1
Liver weight, right0.10.10.2-0.3-0.4-0.4-0.30.5
Locomotor activity0.30.41.00.20.50.50.7-1.0
Locomotor testing distance0.81.42.31.01.11.11.3-1.5
Locomotor testing rearing0.00.10.20.5-0.0-0.00.1-0.4
Locomotion in novel chamber0.30.31.1-0.5-0.00.1-0.51.1
Locomotion in novel chamber post-restriction1.62.63.11.71.81.71.6-1.1
Fecal boli incidents, locomotor time 13.34.85.42.02.22.32.1-2.3
Change in fecal boli incidents, locomotor task2.42.43.7-1.7-1.3-1.2-1.51.9
Time >=10cm from walls, locomotor time 10.30.30.7-0.2-0.6-0.5-0.50.8
Bouts of movement, locomotor time 10.10.10.10.30.30.20.2-0.1
Total resting periods, locomotor time 10.30.40.50.60.70.70.6-0.4
Rest time, locomotor task time 10.40.50.90.50.60.60.7-0.9
Distance moved, locomotor task time 11.21.72.1-1.4-1.2-1.2-1.31.4
Vertical activity count, locomotor time 10.30.71.3-0.7-0.5-0.9-0.71.1
Time >=10cm from walls, locomotor time 20.40.71.3-0.4-0.8-0.8-0.81.1
Bouts of movement, locomotor time 20.00.10.20.30.40.00.2-0.3
Total resting periods, locomotor time 20.10.10.20.30.50.20.3-0.3
Rest time, locomotor task time 20.60.81.1-1.0-0.7-0.6-1.01.0
Distance moved, locomotor task time 20.20.20.4-0.3-0.3-0.5-0.30.6
Vertical activity count, locomotor time 20.00.00.1-0.10.0-0.30.00.3
Light reinforcement 10.10.10.20.30.30.40.5-0.5
Light reinforcement 20.00.10.2-0.5-0.2-0.1-0.2-0.1
Bone: marrow area0.20.30.90.40.30.40.6-0.9
Bone: maximum diameter0.61.21.81.00.91.01.1-1.3
Bone: maximum force0.61.01.21.10.81.01.1-1.0
Bone: maximum moment0.71.21.51.20.91.11.1-1.1
Mean time between licks in bursts0.40.91.81.31.01.00.8-0.3
Mean num. licks in bursts0.00.00.10.20.0-0.1-0.10.2
Cd content in liver0.00.00.1-0.10.30.20.0-0.1
Co content in liver0.00.00.0-0.00.10.00.00.1
Cu content in liver5.06.010.6-3.3-2.4-2.4-2.31.7
Fe content in liver0.50.60.7-0.8-0.7-0.9-0.70.6
K content in liver0.30.31.1-1.1-0.4-0.3-0.1-0.4
Mg content in liver3.43.56.6-2.6-1.7-1.7-1.71.4
Mn content in liver5.56.16.8-2.5-2.6-2.6-2.52.1
Na content in liver0.70.72.6-0.30.40.50.8-1.6
Rb content in liver0.60.71.5-1.2-0.6-0.6-0.70.9
Se content in liver0.50.60.70.40.90.90.7-0.9
Sr content in liver2.11.82.2-0.9-1.5-1.5-1.41.3
Zn content in liver0.20.20.5-0.40.30.30.3-0.7
Bone: minimum diameter0.10.10.10.30.10.30.4-0.4
Time in familiar zone, hab. session 10.30.30.7-0.3-0.4-0.4-0.60.8
Time in novel zone, hab. session 12.82.83.61.21.71.81.7-1.9
Total zone transitions, hab. session 16.28.79.5-3.1-2.8-2.7-3.03.1
Total locomotion distance, hab. session 13.14.45.7-2.4-2.0-2.0-2.12.0
Locomotion velocity, hab. session 14.15.97.1-2.7-2.4-2.3-2.42.3
Time in familiar zone, hab. session 20.80.91.31.21.01.00.8-0.6
Time in novel zone, hab. session 20.10.10.2-0.4-0.3-0.3-0.30.2
Total zone transitions, hab. session 23.14.05.2-2.3-2.1-1.9-1.91.6
Total locomotion distance, hab. session 20.40.51.3-1.1-0.7-0.6-0.50.3
Locomotion velocity, hab. session 20.50.71.6-1.3-0.9-0.8-0.60.4
Novel to familiar place preference ratio0.30.40.7-0.4-0.5-0.5-0.70.8
Novelty place preference0.40.50.9-0.3-0.6-0.6-0.81.0
Time in novel zone, NPP test0.30.30.7-0.2-0.4-0.4-0.60.9
Total zone transitions, NPP test5.17.48.0-2.8-2.8-2.8-2.72.5
Total locomotion distance, NPP test1.42.02.4-1.6-1.5-1.4-1.41.2
Locomotion velocity, NPP test2.13.03.5-1.8-1.9-1.8-1.71.5
Intraocular pressure1.72.53.3-1.1-1.8-1.8-1.41.6
Delta distance traveled before/after self-admin0.70.71.31.20.90.70.8-0.6
Delta ambulatory time before/after self-admin1.11.31.91.21.41.21.1-0.7
Parametrial fat weight0.10.20.40.40.60.60.5-0.1
Pavlov. Cond. lever latency1.11.41.71.21.11.01.3-1.2
Pavlov. Cond. magazine entry latency0.10.10.3-0.4-0.6-0.4-0.2-0.1
Pavlov. Cond. change in total contacts2.93.14.0-2.0-1.8-1.7-1.81.4
Pavlov. Cond. index score0.70.91.2-1.0-1.1-0.9-0.90.7
Pavlov. Cond. latency score0.70.91.1-1.0-1.0-0.9-1.00.8
Pavlov. Cond. lever contacts2.22.63.0-1.7-1.7-1.5-1.71.4
Pavlov. Cond. magazine entry number0.50.61.00.81.00.90.7-0.4
Pavlov. Cond. intertrial magazine entries0.60.71.5-1.2-0.5-0.6-0.80.9
Pavlov. Cond. lever-magazine prob. diff.0.80.91.3-1.0-1.2-1.0-0.90.7
Pavlov. Cond. response bias0.91.11.6-1.1-1.2-1.1-1.00.8
Pavlov. Cond. lever latency0.71.02.1-1.5-0.8-0.8-0.90.8
Pavlov. Cond. magazine entry latency0.30.40.4-0.6-0.7-0.6-0.60.5
Pavlov. Cond. change in total contacts0.10.20.90.9-0.1-0.00.4-0.4
Pavlov. Cond. index score0.20.20.50.70.20.20.5-0.5
Pavlov. Cond. latency score0.00.10.10.4-0.0-0.00.2-0.3
Pavlov. Cond. lever contacts0.60.91.91.40.80.80.8-0.7
Pavlov. Cond. magazine entry number0.00.00.0-0.10.10.1-0.0-0.0
Pavlov. Cond. intertrial magazine entries1.42.02.7-1.4-1.2-1.3-1.51.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.70.20.30.5-0.5
Pavlov. Cond. response bias0.70.91.61.30.80.91.0-0.9
Time in closed arm before self-admin2.53.23.82.01.71.81.8-1.6
Time in closed arm after self-admin3.53.75.02.02.22.11.9-1.3
Time in open arm before self-admin0.40.40.8-0.6-0.3-0.7-0.50.9
Time in open arm after self-admin3.03.34.2-1.6-1.8-1.7-1.92.0
Bone: periosteal estimation0.51.01.41.00.71.01.0-1.2
Bone: periosteal perimeter1.32.23.01.71.41.51.4-1.3
Bone: post-yield work0.40.71.01.00.90.90.7-0.4
Progressive ratio test 1 active lever presses0.70.91.2-1.1-0.9-1.0-0.81.0
Progressive ratio test 1 breakpoint0.60.70.9-1.0-0.7-0.8-0.70.9
Progressive ratio test 1 inactive lever presses0.20.30.50.70.60.40.5-0.3
Progressive ratio test 2 active lever presses0.20.20.5-0.7-0.5-0.5-0.30.3
Progressive ratio test 2 breakpoint0.20.20.5-0.7-0.5-0.5-0.30.3
Progressive ratio test 2 inactive lever presses0.10.10.10.30.40.30.3-0.1
Incentive Sensitization - Responses0.00.00.10.0-0.2-0.10.2-0.4
Incentive Sensitization - Breakpoint0.10.10.30.2-0.1-0.00.3-0.6
Sum of active levers in priming session hrs 5-64.34.04.5-2.1-1.9-2.0-2.11.9
Progressive ratio0.10.10.20.50.40.4-0.10.2
Food seeking constrained by brief footshock0.20.31.1-0.10.0-0.10.4-1.0
Seeking ratio, punishment vs. effort0.50.71.2-1.1-1.0-1.0-0.40.1
Retroperitoneal fat weight0.41.52.21.31.01.01.5-1.3
Reaction time number correct0.20.41.51.20.30.50.30.2
Reaction time mean minus median0.82.02.9-1.3-1.5-1.7-1.31.2
Reaction time mean minus median AUC1.02.53.5-1.5-1.7-1.9-1.41.4
Reaction time num false alarms0.81.12.1-1.4-1.1-1.0-0.90.5
Reaction time num false alarms AUC0.91.42.5-1.6-1.3-1.2-1.00.6
Reaction time trials correct on left0.20.41.51.20.30.50.30.2
Reaction time trials on left0.20.41.41.20.20.50.20.3
Reaction time mean0.30.60.9-0.9-0.8-0.9-0.50.5
Reaction time mean AUC0.40.71.0-1.0-0.8-1.0-0.60.6
Median of all reaction times0.10.20.4-0.7-0.4-0.5-0.1-0.0
Reaction time omissions1.11.62.1-1.2-1.5-1.4-1.11.0
Reaction time false alarm rate0.91.33.2-1.8-1.1-1.1-0.80.2
Reaction time premature initiation rate0.40.60.9-0.4-0.8-1.0-0.80.7
Reaction time premature initiations0.30.60.90.2-0.8-0.9-0.81.0
Std. dev. reaction times0.81.52.3-1.2-1.3-1.5-1.11.0
Reaction time trials completed0.20.41.41.20.20.50.20.3
Reaction time trials AUC0.20.41.51.20.20.40.20.3
Run reversals in cocaine runway, females0.20.20.5-0.3-0.5-0.7-0.30.4
Run reversals in cocaine runway, males1.21.31.61.31.21.21.1-0.8
Latency to leave start box in cocaine runway5.36.07.02.62.62.52.3-2.1
Latency to leave start box in cocaine runway, F6.87.79.83.12.92.92.6-2.2
Latency to leave start box in cocaine runway, M0.50.50.90.40.60.60.7-0.9
Std. dev. time between licks in bursts0.91.21.81.20.80.91.1-1.3
Total sessions with >9 infusions0.00.00.10.10.20.10.1-0.4
Short access day 1 total inactive lever presses1.92.53.4-0.5-1.8-1.5-1.81.8
Short access day 10 total inactive lever presses0.41.01.71.30.90.91.0-1.0
Short access day 1 total infusions0.10.10.20.3-0.4-0.4-0.1-0.3
Short access day 10 total infusions0.20.30.60.10.50.40.6-0.8
Short access total infusions0.10.10.20.50.40.30.3-0.4
Short access day 1 locomotion1.01.23.10.50.70.81.2-1.7
Short access day 10 total locomotion0.51.03.10.10.40.61.1-1.8
Short access total locomotion0.80.92.40.30.80.71.0-1.6
One hour access (0.3 mA shock)0.50.60.6-0.7-0.8-0.8-0.70.8
Compulsive drug intake3.44.05.3-1.9-1.7-1.8-2.22.3
One hour access (shock baseline)1.11.72.31.11.11.21.5-1.5
Social response proportion1.92.23.0-1.7-1.7-1.6-1.30.9
Social responses0.10.10.2-0.2-0.4-0.4-0.20.1
Social time0.10.10.10.40.30.20.3-0.1
Soleus weight1.64.75.52.12.32.32.2-1.8
Bone: stiffness0.00.10.20.30.10.10.4-0.2
Tibialis anterior weight0.20.61.1-0.5-0.8-0.8-0.81.1
Time to tail flick, vehicle, before self-admin3.23.34.5-2.0-1.5-1.4-2.02.1
Time to tail flick, vehicle, after self-admin0.81.02.11.40.91.10.8-0.4
Time to tail flick, test, before self-admin0.40.40.60.70.70.70.6-0.4
Time to tail flick, test, after self-admin0.60.61.20.91.10.80.6-0.1
Delta time to tail flick, vehicle, before/after SA4.94.77.02.72.02.02.1-1.9
Delta time to tail flick, test, before/after SA0.40.40.5-0.6-0.5-0.7-0.70.7
Tibia length0.61.72.31.41.51.51.2-0.7
Ambulatory time before self-admin0.30.40.7-0.8-0.8-0.8-0.30.0
Ambulatory time after self-admin0.20.20.60.10.2-0.00.7-0.8
Bone: tissue strength0.60.61.11.00.70.80.7-0.2
Total heroin consumption1.11.31.6-1.1-1.2-1.0-1.31.2
Bone: trabecular number0.61.12.00.60.91.01.1-1.4
Bone: trabecular spacing0.00.00.10.1-0.0-0.2-0.20.4
Bone: trabecular thickness3.34.16.72.61.71.91.9-1.8
Bone: trabecular tissue density0.10.10.1-0.0-0.3-0.4-0.30.3
Water consumed over 24 hours0.10.10.2-0.4-0.0-0.0-0.30.4
Number of responses in last shaping day0.70.71.21.10.90.90.8-0.5