Hub : Genes

LOC120095180

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability LOC120095180 0.04 0.04 2.0e-04 0.04 0.04 0.03 0.04 4.4e-05 2.7e-04 7.0e-04 2.2e-04
2 IC gene expression LOC120095180 0.29 0.13 3.3e-12 0.3 0.13 0.28 0.3 4.1e-13 3.0e-06 2.5e-12 5.4e-13
3 PL gene expression LOC120095180 0.42 0.1 0.0e+00 0.54 0.52 0.53 0.53 4.3e-69 2.5e-66 1.2e-68 8.9e-69
4 OFC gene expression LOC120095180 0.33 0.16 3.2e-07 0.26 0.21 0.24 0.28 5.4e-07 8.6e-06 1.9e-06 2.4e-07
5 pVTA gene expression LOC120095180 0.18 0.08 0.0e+00 0.26 0.25 0.27 0.27 2.5e-21 6.6e-20 5.6e-22 8.6e-22
6 NAcc gene expression LOC120095180 0.54 0.05 0.0e+00 0.55 0.56 0.56 0.56 1.8e-101 4.7e-103 1.3e-103 3.5e-103
7 PL mRNA stability LOC120095180 0.03 0.03 2.3e-03 0.02 0.02 0.01 0.02 1.4e-03 3.1e-03 1.4e-02 3.0e-03
8 LHb gene expression LOC120095180 0.2 0.12 4.3e-04 0.09 0.12 0.1 0.1 3.4e-03 1.0e-03 2.3e-03 3.0e-03
9 BLA gene expression LOC120095180 0.19 0.09 4.7e-14 0.22 0.22 0.22 0.22 1.3e-11 6.1e-12 1.1e-11 9.9e-12
10 Liver gene expression LOC120095180 0.03 0.03 4.4e-03 0.01 0.01 0 0 2.6e-02 3.4e-02 1.0e-01 8.4e-02
11 IL gene expression LOC120095180 0.57 0.2 4.4e-09 0.3 0.26 0.26 0.31 6.2e-08 4.6e-07 4.5e-07 4.3e-08
12 Brain gene expression LOC120095180 0.42 0.21 0.0e+00 0.36 0.36 0.36 0.36 2.1e-34 1.7e-34 3.4e-35 5.6e-35

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.32.23.2-1.7-1.8-1.4-1.4-1.5-1.4-1.4-1.4-1.41.2-1.5-1.5
Area under the delay curve0.00.10.20.00.00.20.30.20.30.40.30.2-0.20.30.1
BMI with tail19.767.877.7-8.8-8.8-8.1-8.1-8.4-8.3-8.1-8.2-8.08.0-8.2-7.7
BMI without tail1.75.16.4-2.5-2.5-2.2-2.2-2.3-2.3-2.2-2.2-2.22.2-2.2-2.0
Body weight1.14.97.0-2.6-2.6-2.0-1.9-2.2-2.1-1.9-2.4-2.32.0-2.0-2.2
Weight adjusted by age0.10.10.40.40.50.20.20.30.20.10.50.4-0.60.30.2
Bone surface0.40.81.3-1.1-1.1-0.8-0.8-1.0-0.8-0.8-0.9-0.90.7-0.9-1.0
Bone volume1.11.92.7-1.6-1.6-1.3-1.3-1.4-1.3-1.3-1.5-1.41.1-1.4-1.5
Breakpoint value in progressive ratio session2.22.73.31.81.81.71.61.51.51.61.61.7-1.51.41.8
Number of licking bursts0.81.41.61.01.01.21.21.21.21.21.21.2-1.21.21.3
Context. condit. distance diff. score1.01.21.4-1.0-1.0-1.2-1.2-1.1-1.2-1.2-1.1-1.11.0-1.1-1.0
Locomotion velocity, session 10.00.00.10.10.10.10.10.10.00.10.20.2-0.30.10.2
Locomotion distance, session 14.96.26.82.32.32.62.62.42.52.62.52.5-2.52.42.5
Locomotion velocity, session 21.01.11.41.21.21.11.11.11.01.11.01.0-1.11.10.9
Locomotion distance, session 26.69.29.63.03.03.13.13.03.03.13.13.1-2.92.93.1
Locomotion velocity, session 30.50.51.0-0.6-0.6-0.7-0.7-0.7-0.6-0.7-0.8-0.81.0-0.8-0.7
Locomotion distance, session 31.11.21.31.21.11.11.11.11.11.11.11.1-0.91.01.1
Stereotopy head waving bouts, day 34.14.85.5-2.3-2.2-2.1-2.1-2.2-2.1-2.1-2.3-2.22.3-2.2-2.0
Stereotopy head waving duration, day 33.33.94.2-2.1-2.0-2.0-2.0-2.0-1.9-2.0-2.1-2.02.0-1.9-1.9
Locomotion velocity, session 71.41.62.01.11.01.41.41.31.41.41.11.1-1.21.31.2
Locomotion distance, session 77.08.810.12.72.63.23.23.03.23.22.92.9-2.93.02.9
Stereotopy head waving bouts, day 70.30.30.5-0.7-0.6-0.5-0.5-0.6-0.5-0.5-0.6-0.60.7-0.6-0.5
Stereotopy head waving duration, day 70.40.50.7-0.7-0.6-0.6-0.6-0.7-0.6-0.6-0.7-0.70.8-0.8-0.6
Locomotion velocity, session 80.70.81.2-0.6-0.6-1.0-1.0-0.9-1.1-1.0-0.9-0.91.0-1.0-0.8
Locomotion distance, session 80.50.80.90.90.90.80.80.90.80.81.00.9-0.80.81.0
Degree of sensitization distance0.40.40.50.40.40.70.70.60.70.70.50.5-0.70.70.5
Degree of sensitization stereotypy0.20.20.30.40.40.40.40.40.40.40.50.5-0.40.30.5
Conditioned locomotion1.92.22.7-1.4-1.4-1.6-1.6-1.4-1.6-1.6-1.4-1.41.2-1.3-1.6
Cocaine response after cond. corrected5.46.57.0-2.6-2.6-2.6-2.6-2.6-2.6-2.6-2.4-2.42.5-2.5-2.4
Cocaine response after cond. not corrected3.13.64.1-2.0-2.0-1.9-1.9-2.0-1.9-1.9-1.8-1.81.8-1.9-1.8
Cocaine response before conditioning2.73.23.61.81.81.91.91.81.91.91.81.8-1.71.71.8
Saline control response0.10.10.40.00.10.10.10.20.20.10.40.4-0.60.40.3
Bone: connectivity density0.30.50.9-0.9-1.0-0.6-0.6-0.8-0.6-0.6-0.6-0.60.5-0.8-0.7
Bone: cortical apparent density4.66.36.62.62.52.52.52.62.52.52.52.4-2.52.52.4
Bone: cortical area0.50.71.3-1.1-1.1-0.7-0.7-0.9-0.7-0.7-0.8-0.90.7-0.8-0.9
Bone: cortical porosity0.20.20.3-0.6-0.6-0.4-0.4-0.5-0.4-0.4-0.5-0.50.5-0.4-0.5
Bone: cortical porosity0.30.40.6-0.8-0.8-0.5-0.5-0.6-0.5-0.5-0.6-0.60.5-0.5-0.6
Bone: cortical thickness0.10.10.2-0.4-0.5-0.3-0.3-0.3-0.3-0.3-0.3-0.40.3-0.3-0.4
Bone: cortical thickness0.50.50.70.80.80.80.80.70.80.80.80.8-0.50.60.7
Bone: cortical tissue density5.37.27.62.82.72.72.72.72.72.72.62.6-2.72.72.6
Condit. Reinf. active minus inactive responses1.41.61.91.31.31.21.21.31.21.21.21.2-1.21.41.3
Condit. Reinf. active-inactive response ratio0.00.00.00.00.1-0.0-0.00.00.0-0.0-0.1-0.00.2-0.00.0
Condit. Reinf. active responses1.41.72.01.41.41.31.31.31.21.31.21.3-1.21.41.4
Condit. Reinf. inactive responses0.81.01.40.90.90.90.91.00.90.91.11.1-1.11.11.2
Incentive salience index mean2.22.73.21.81.81.61.61.71.51.61.61.7-1.61.71.7
Condit. Reinf. lever presses2.43.44.02.01.91.71.71.81.71.71.91.9-1.81.82.0
Condit. Reinf. active minus inactive responses0.10.20.30.10.00.40.50.30.40.50.50.5-0.60.40.5
Condit. Reinf. active-inactive response ratio0.20.20.40.10.00.40.40.30.30.40.60.6-0.60.40.7
Condit. Reinf. active responses0.10.10.3-0.1-0.10.40.40.20.40.40.40.4-0.50.30.3
Condit. Reinf. inactive responses0.00.00.0-0.1-0.10.10.10.00.20.1-0.0-0.1-0.1-0.0-0.2
Condit. Reinf. lever presses0.10.20.40.40.40.30.40.40.40.40.50.4-0.60.40.3
Condit. Reinf. lever reinforcers received0.10.20.4-0.0-0.00.50.50.30.50.50.50.5-0.60.40.4
Conditioned reinforcement - actives0.61.01.50.40.51.01.00.91.11.10.91.0-1.21.21.1
Conditioned reinforcement - inactives0.10.10.2-0.4-0.40.30.20.10.30.20.10.1-0.40.30.1
Conditioned locomotion0.20.30.7-0.8-0.8-0.6-0.5-0.6-0.5-0.6-0.4-0.40.3-0.4-0.2
Patch foraging indifference point 0 sec1.22.32.8-1.3-1.2-1.7-1.7-1.5-1.7-1.6-1.4-1.51.5-1.5-1.6
Patch foraging indifference point AUC0.00.00.10.30.20.10.10.20.20.10.10.1-0.10.20.1
Delay disc. indifference point, 0s delay0.10.10.30.10.10.10.20.10.20.30.30.2-0.60.20.0
Delay disc. indifference point, 16s delay1.11.21.9-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.1-1.11.4-1.1-1.1
Delay disc. indifference point, 2s delay0.10.10.40.10.10.20.30.20.30.30.30.2-0.60.30.0
Delay disc. indifference point, 24s delay0.50.50.90.60.60.70.90.70.71.00.70.7-0.60.80.7
Delay disc. indifference point, 4s delay1.51.52.21.11.11.31.41.21.51.41.21.1-1.31.20.9
Delay disc. indifference point, 8s delay0.00.10.10.10.10.20.30.30.20.40.30.2-0.20.30.2
Indifference point function ln k0.00.10.10.20.30.20.20.20.20.20.30.3-0.20.30.2
Indifference point function log k0.00.10.10.20.30.20.20.20.20.20.30.3-0.20.30.2
Patch foraging total patch changes 0 sec1.32.42.9-1.3-1.3-1.7-1.7-1.5-1.7-1.7-1.5-1.51.6-1.6-1.7
Patch foraging total patch changes 12 sec0.00.00.1-0.1-0.1-0.1-0.1-0.0-0.0-0.1-0.0-0.0-0.2-0.0-0.1
Patch foraging total patch changes 18 sec1.62.42.7-1.5-1.4-1.6-1.6-1.5-1.6-1.6-1.5-1.61.6-1.6-1.6
Patch foraging total patch changes 24 sec0.61.01.2-0.8-0.8-1.1-1.1-1.0-1.0-1.0-0.9-1.00.9-1.1-1.0
Patch foraging total patch changes 6 sec0.71.11.4-0.9-1.0-1.1-1.1-1.0-1.1-1.1-1.1-1.11.2-1.1-1.1
Patch foraging time to switch 0 sec0.10.20.40.20.30.40.40.40.50.50.50.5-0.60.40.3
Patch foraging water rate 0 sec1.53.13.5-1.6-1.6-1.8-1.8-1.8-1.8-1.8-1.8-1.81.9-1.8-1.6
Patch foraging water rate 12 sec0.30.71.3-0.7-0.7-0.7-0.7-0.8-0.8-0.7-0.9-0.91.1-0.9-0.7
Patch foraging water rate 18 sec0.00.00.10.30.30.00.00.10.0-0.1-0.0-0.0-0.1-0.0-0.0
Patch foraging water rate 24 sec1.11.51.7-1.1-1.0-1.2-1.2-1.2-1.2-1.3-1.3-1.31.3-1.3-1.3
Patch foraging water rate 6 sec0.00.10.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2-0.1-0.10.5-0.30.1
Seeking ratio, delayed vs. immediate footshock2.93.54.1-2.0-2.0-2.0-2.0-1.9-1.8-2.0-1.7-1.81.3-1.7-2.0
Distance traveled before self-admin1.41.82.31.00.91.41.41.31.41.41.41.4-1.51.31.5
Distance traveled after self-admin0.00.00.1-0.4-0.40.00.1-0.10.00.10.10.00.3-0.10.2
Extensor digitorum longus weight1.03.84.1-2.0-2.0-1.9-1.9-1.9-1.8-1.9-2.0-2.01.9-1.9-2.0
Bone: elastic displacement0.00.00.0-0.1-0.1-0.2-0.2-0.1-0.1-0.2-0.2-0.10.1-0.2-0.1
Bone: elastic work0.00.00.1-0.2-0.2-0.2-0.2-0.0-0.0-0.2-0.0-0.0-0.20.0-0.1
Bone: endosteal estimation0.10.10.3-0.5-0.5-0.3-0.3-0.4-0.3-0.3-0.4-0.40.1-0.3-0.4
Bone: endosteal perimeter0.30.70.8-0.9-0.9-0.7-0.7-0.8-0.8-0.7-0.8-0.80.7-0.8-0.9
Epididymis fat weight0.10.31.2-1.1-1.0-0.3-0.3-0.6-0.4-0.3-0.5-0.50.4-0.4-0.2
Delta time in closed arm before/after self-admin0.30.30.5-0.6-0.6-0.4-0.4-0.5-0.4-0.4-0.6-0.60.3-0.4-0.7
Delta time in open arm before/after self-admin0.90.91.31.21.20.90.90.90.90.91.01.0-0.90.70.9
Diff in mean of infusions in LGA sessions1.82.13.11.31.31.61.61.31.51.61.41.5-1.71.21.5
Delay discount exponential model param0.10.20.4-0.2-0.2-0.4-0.5-0.4-0.5-0.6-0.4-0.40.4-0.4-0.2
Extinction: sum of active levers before priming1.11.32.20.90.91.31.21.11.21.21.11.1-1.51.00.9
Active lever presses in extinction session 60.10.10.5-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.30.7-0.6-0.2
Bone: final force0.10.20.7-0.8-0.8-0.4-0.4-0.4-0.4-0.4-0.4-0.40.2-0.3-0.4
Bone: final moment0.20.41.0-0.9-1.0-0.6-0.6-0.6-0.6-0.6-0.5-0.50.4-0.5-0.5
Food consumed during 24 hour testing period1.92.63.11.81.81.61.61.71.61.61.61.6-1.41.61.6
Glucose2.03.13.6-1.5-1.5-1.9-1.9-1.7-1.8-1.9-1.9-1.91.6-1.8-1.9
Heart weight0.71.12.3-1.5-1.5-0.7-0.7-1.0-0.9-0.8-1.1-1.00.8-0.9-1.1
Delay discount hyperbolic model param0.10.10.3-0.2-0.2-0.4-0.5-0.3-0.5-0.6-0.4-0.30.4-0.3-0.2
Intermittent access intake day 1-15 change0.00.00.1-0.0-0.00.10.10.10.10.10.30.3-0.00.10.3
Intermittent access intake escalation0.00.00.1-0.1-0.10.10.10.00.00.10.20.20.00.00.3
Intermittent access intake escalation 20.30.30.5-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.4-0.40.7-0.7-0.3
Intermitt. access day 1 inactive lever presses0.00.00.0-0.0-0.00.10.10.00.20.20.10.1-0.10.10.2
Intermitt. access day 15 inactive lever presses1.22.42.9-1.5-1.4-1.5-1.5-1.5-1.5-1.6-1.5-1.61.7-1.6-1.6
Intermitt. access escalation Index0.30.50.70.90.90.60.60.70.60.60.70.7-0.40.60.8
Intermittent access day 1 total infusions0.00.10.20.10.00.40.40.20.40.40.10.1-0.30.40.1
Intermittent access day 15 total infusions0.10.10.20.0-0.00.40.50.30.40.40.30.3-0.40.40.4
Intermittent access terminal intake (last 3 days)0.00.00.1-0.3-0.40.10.1-0.00.10.10.00.0-0.20.10.1
Intermittent access total infusions0.00.00.2-0.4-0.40.10.1-0.10.10.1-0.1-0.1-0.20.1-0.1
Intermittent access day 1 locomotion0.40.40.60.50.50.80.80.70.80.80.50.6-0.70.80.5
Intermittent access day 15 total locomotion0.20.40.60.10.10.80.70.50.70.70.50.6-0.70.70.5
Intermittent access total locomotion0.10.10.30.0-0.00.40.40.30.40.40.30.3-0.60.40.3
Intermittent access standard deviation0.51.01.2-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.9-1.01.0-1.1-0.9
Left kidney weight0.00.10.2-0.4-0.5-0.1-0.1-0.2-0.2-0.1-0.2-0.20.0-0.1-0.3
Right kidney weight0.41.72.2-1.4-1.5-1.4-1.3-1.3-1.4-1.4-1.3-1.30.9-1.2-1.3
Cocaine induced anxiety0.10.10.2-0.5-0.5-0.4-0.4-0.3-0.2-0.4-0.3-0.2-0.1-0.2-0.2
Post-drug Anxiety0.60.71.30.70.70.80.80.81.00.80.80.8-1.20.90.8
Baseline Anxiety1.31.62.41.51.51.21.21.41.31.21.11.1-0.91.21.1
Tail length18.672.579.98.98.88.58.68.78.68.58.48.2-8.38.58.0
Length with tail6.930.232.25.65.65.75.75.65.65.75.35.1-5.55.64.9
Length without tail0.20.71.4-1.2-1.2-0.5-0.5-0.8-0.5-0.5-0.9-0.90.5-0.7-1.0
Times rat made contact with spout0.70.91.21.11.10.90.91.00.80.90.80.9-0.81.00.9
Lifetime Intake0.00.00.1-0.2-0.2-0.0-0.0-0.1-0.0-0.0-0.1-0.1-0.00.0-0.2
Liver weight, left0.00.00.1-0.1-0.1-0.2-0.2-0.2-0.3-0.1-0.2-0.10.2-0.20.0
Liver weight, right0.10.20.30.30.30.50.50.40.50.60.30.2-0.40.30.2
Locomotor activity0.10.10.3-0.6-0.6-0.1-0.1-0.3-0.3-0.1-0.2-0.20.5-0.2-0.0
Locomotor testing distance0.50.91.7-1.3-1.3-0.8-0.8-1.0-1.0-0.9-0.7-0.71.0-0.8-0.6
Locomotor testing rearing0.00.10.4-0.6-0.7-0.3-0.3-0.3-0.3-0.3-0.0-0.00.2-0.1-0.1
Locomotion in novel chamber0.20.30.90.20.20.70.60.40.50.70.50.5-0.90.40.5
Locomotion in novel chamber post-restriction1.22.02.9-1.7-1.7-1.3-1.3-1.5-1.5-1.3-1.4-1.30.8-1.3-1.5
Fecal boli incidents, locomotor time 12.84.16.4-1.7-1.7-2.0-1.9-1.9-2.1-1.9-2.1-2.12.5-2.1-2.1
Change in fecal boli incidents, locomotor task2.62.63.21.41.31.81.71.51.81.71.51.6-1.81.61.6
Time >=10cm from walls, locomotor time 10.10.10.50.0-0.00.30.30.20.20.20.50.5-0.70.20.4
Bouts of movement, locomotor time 10.30.30.5-0.7-0.6-0.6-0.4-0.6-0.5-0.4-0.6-0.60.5-0.5-0.5
Total resting periods, locomotor time 10.70.81.1-1.0-1.0-1.0-0.8-0.9-0.9-0.8-0.9-1.00.8-0.9-0.8
Rest time, locomotor task time 10.30.30.5-0.4-0.4-0.7-0.6-0.5-0.6-0.6-0.6-0.60.7-0.5-0.5
Distance moved, locomotor task time 11.72.53.01.51.51.61.61.61.61.61.51.6-1.71.61.6
Vertical activity count, locomotor time 10.30.70.90.70.70.90.80.90.90.90.80.8-0.90.90.9
Time >=10cm from walls, locomotor time 20.40.50.70.70.70.80.80.80.70.80.70.7-0.60.70.7
Bouts of movement, locomotor time 20.00.00.2-0.3-0.3-0.2-0.1-0.1-0.2-0.2-0.1-0.0-0.40.1-0.2
Total resting periods, locomotor time 20.00.10.2-0.3-0.4-0.2-0.2-0.1-0.2-0.3-0.1-0.1-0.50.0-0.3
Rest time, locomotor task time 20.40.51.11.01.00.60.50.70.50.50.70.7-0.40.60.8
Distance moved, locomotor task time 20.20.20.40.40.40.60.60.60.60.60.30.3-0.30.50.3
Vertical activity count, locomotor time 20.10.10.30.20.10.50.40.50.50.50.20.2-0.40.50.1
Light reinforcement 10.00.10.2-0.2-0.3-0.2-0.2-0.2-0.4-0.3-0.1-0.10.4-0.2-0.0
Light reinforcement 20.20.30.40.70.50.40.40.60.40.40.60.6-0.60.60.6
Bone: marrow area0.00.10.2-0.4-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.30.1-0.2-0.4
Bone: maximum diameter0.40.81.1-1.0-1.1-0.8-0.8-1.0-0.9-0.8-0.9-0.80.9-0.9-0.8
Bone: maximum force0.61.01.8-1.3-1.3-0.9-0.9-1.0-0.9-0.9-1.0-1.00.7-0.9-1.0
Bone: maximum moment0.81.52.2-1.5-1.5-1.1-1.1-1.2-1.2-1.1-1.2-1.21.0-1.1-1.2
Mean time between licks in bursts0.71.62.1-1.4-1.4-1.2-1.2-1.3-1.2-1.2-1.3-1.31.0-1.2-1.4
Mean num. licks in bursts0.10.10.2-0.1-0.1-0.4-0.4-0.3-0.4-0.4-0.4-0.40.3-0.3-0.4
Cd content in liver0.00.00.10.0-0.0-0.0-0.00.00.0-0.00.20.2-0.30.10.2
Co content in liver0.00.00.0-0.1-0.0-0.1-0.1-0.0-0.0-0.10.00.1-0.00.10.2
Cu content in liver10.112.014.03.03.03.73.73.53.63.53.43.5-3.73.63.5
Fe content in liver1.21.52.80.80.71.31.31.31.41.21.21.2-1.71.40.9
K content in liver1.51.42.50.90.91.31.31.31.41.20.91.0-1.61.40.8
Mg content in liver7.57.710.32.32.33.03.02.83.02.92.52.6-3.23.02.4
Mn content in liver4.75.26.22.52.52.22.22.32.22.12.42.3-2.22.32.2
Na content in liver0.30.40.80.30.30.70.70.60.70.70.40.5-0.90.70.3
Rb content in liver1.01.21.80.60.51.31.30.91.11.21.11.1-1.11.11.4
Se content in liver0.10.20.2-0.4-0.4-0.5-0.5-0.4-0.5-0.4-0.4-0.30.2-0.3-0.4
Sr content in liver1.00.81.71.31.30.70.71.00.80.70.90.8-0.80.80.7
Zn content in liver0.40.51.00.30.30.80.80.70.80.70.50.6-1.00.80.6
Bone: minimum diameter0.10.10.3-0.6-0.6-0.1-0.1-0.3-0.1-0.1-0.3-0.30.0-0.2-0.4
Time in familiar zone, hab. session 10.10.10.20.20.10.30.30.40.30.30.50.5-0.40.40.4
Time in novel zone, hab. session 12.12.12.7-1.3-1.3-1.3-1.3-1.5-1.3-1.3-1.6-1.61.7-1.6-1.4
Total zone transitions, hab. session 17.09.810.73.03.13.33.33.13.13.33.13.2-2.93.03.2
Total locomotion distance, hab. session 14.46.27.12.22.22.72.72.42.62.72.52.5-2.42.42.6
Locomotion velocity, hab. session 15.67.98.72.52.52.92.92.82.92.92.82.8-2.82.82.8
Time in familiar zone, hab. session 21.41.42.1-1.1-1.1-1.2-1.2-1.2-1.3-1.2-1.1-1.11.4-1.2-1.0
Time in novel zone, hab. session 20.20.20.60.30.30.40.40.40.50.40.50.4-0.70.50.3
Total zone transitions, hab. session 24.55.86.22.32.32.42.42.42.42.42.52.5-2.42.32.5
Total locomotion distance, hab. session 21.21.51.91.01.01.41.41.21.21.41.21.2-1.31.21.3
Locomotion velocity, hab. session 21.41.82.31.21.21.51.51.31.41.51.31.3-1.41.31.4
Novel to familiar place preference ratio0.30.30.50.40.40.50.50.50.70.50.60.6-0.50.40.5
Novelty place preference0.20.20.40.30.30.40.40.40.60.40.50.5-0.40.30.4
Time in novel zone, NPP test0.10.10.20.20.20.30.30.20.40.30.40.4-0.10.20.3
Total zone transitions, NPP test5.78.39.22.92.92.92.92.82.72.93.03.0-2.82.93.0
Total locomotion distance, NPP test2.02.83.21.51.51.71.71.61.71.71.81.8-1.81.71.7
Locomotion velocity, NPP test2.63.74.11.81.82.02.01.91.92.02.02.0-2.01.91.9
Intraocular pressure1.01.51.91.11.11.31.31.21.31.41.31.2-1.21.21.1
Delta distance traveled before/after self-admin1.41.52.0-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.4-1.2-1.3
Delta ambulatory time before/after self-admin1.41.72.2-1.2-1.2-1.3-1.4-1.2-1.2-1.4-1.3-1.31.5-1.2-1.3
Parametrial fat weight0.10.20.7-0.8-0.8-0.3-0.3-0.4-0.3-0.3-0.5-0.40.3-0.3-0.5
Pavlov. Cond. lever latency1.21.52.1-1.3-1.3-1.0-1.1-1.2-1.1-1.0-1.4-1.41.2-1.2-1.4
Pavlov. Cond. magazine entry latency0.10.20.30.40.30.40.40.40.40.40.50.5-0.30.40.6
Pavlov. Cond. change in total contacts4.04.24.82.02.02.02.02.02.02.02.12.2-2.12.02.2
Pavlov. Cond. index score0.91.11.61.11.01.01.01.01.01.01.21.2-1.11.01.3
Pavlov. Cond. latency score0.91.11.61.11.10.90.91.00.90.91.21.2-1.11.01.3
Pavlov. Cond. lever contacts2.63.13.71.91.91.61.61.71.61.61.91.9-1.81.71.9
Pavlov. Cond. magazine entry number0.81.01.1-0.8-0.8-1.0-1.0-0.9-1.0-1.0-1.0-1.11.0-1.0-1.1
Pavlov. Cond. intertrial magazine entries1.11.32.00.91.01.11.11.11.11.11.11.1-1.41.21.1
Pavlov. Cond. lever-magazine prob. diff.0.91.11.61.01.00.90.91.00.90.91.21.2-1.01.01.3
Pavlov. Cond. response bias1.11.31.71.11.01.11.11.11.11.11.31.3-1.11.11.3
Pavlov. Cond. lever latency1.92.53.01.31.31.71.71.51.71.71.51.6-1.51.61.7
Pavlov. Cond. magazine entry latency0.20.20.70.80.80.30.30.50.40.30.30.3-0.30.50.2
Pavlov. Cond. change in total contacts0.50.81.1-0.7-0.7-1.0-1.0-0.9-1.0-1.0-0.8-1.00.9-0.9-1.0
Pavlov. Cond. index score0.50.70.9-0.6-0.5-0.9-0.9-0.8-0.9-0.9-0.8-0.90.8-0.8-0.9
Pavlov. Cond. latency score0.20.30.4-0.2-0.2-0.6-0.6-0.5-0.6-0.6-0.5-0.60.6-0.5-0.7
Pavlov. Cond. lever contacts1.62.32.8-1.2-1.2-1.7-1.7-1.5-1.6-1.7-1.4-1.51.4-1.5-1.5
Pavlov. Cond. magazine entry number0.10.10.20.00.00.30.30.20.30.30.40.4-0.20.20.5
Pavlov. Cond. intertrial magazine entries1.52.32.91.21.21.71.71.41.61.71.61.6-1.41.41.7
Pavlov. Cond. lever-magazine prob. diff.0.60.71.0-0.6-0.6-1.0-1.0-0.8-0.9-1.0-0.9-0.90.8-0.8-1.0
Pavlov. Cond. response bias1.52.02.4-1.2-1.2-1.5-1.5-1.4-1.5-1.5-1.4-1.51.3-1.4-1.5
Time in closed arm before self-admin2.83.64.7-2.2-2.2-1.7-1.8-1.9-1.7-1.8-1.9-2.01.9-1.8-1.9
Time in closed arm after self-admin3.43.65.3-2.3-2.3-1.7-1.7-1.9-1.6-1.7-2.0-2.01.7-1.7-2.1
Time in open arm before self-admin0.50.51.10.70.70.70.70.70.70.70.70.8-1.00.70.6
Time in open arm after self-admin2.22.53.41.81.81.51.51.51.41.51.61.6-1.41.31.6
Bone: periosteal estimation0.40.71.4-1.1-1.2-0.8-0.8-0.9-0.8-0.8-0.8-0.80.6-0.8-0.9
Bone: periosteal perimeter1.42.43.0-1.7-1.7-1.5-1.5-1.6-1.5-1.5-1.5-1.51.5-1.6-1.6
Bone: post-yield work0.91.41.6-1.2-1.2-1.1-1.1-1.2-1.1-1.1-1.2-1.21.1-1.2-1.2
Progressive ratio test 1 active lever presses1.01.21.61.11.11.01.01.11.11.01.11.1-1.31.31.1
Progressive ratio test 1 breakpoint0.80.91.21.01.00.80.80.90.90.91.01.0-1.11.11.0
Progressive ratio test 1 inactive lever presses0.40.60.8-0.7-0.6-0.9-0.8-0.8-0.8-0.8-0.7-0.70.9-0.7-0.6
Progressive ratio test 2 active lever presses0.70.91.40.20.21.11.10.81.21.00.90.9-1.21.10.9
Progressive ratio test 2 breakpoint0.70.81.30.20.21.11.10.81.11.00.90.9-1.11.10.8
Progressive ratio test 2 inactive lever presses0.10.10.6-0.8-0.70.00.0-0.20.1-0.1-0.1-0.1-0.20.0-0.2
Incentive Sensitization - Responses0.20.30.6-0.5-0.60.60.60.20.60.50.40.4-0.80.50.2
Incentive Sensitization - Breakpoint0.20.20.5-0.7-0.70.50.50.10.50.40.30.3-0.60.40.1
Sum of active levers in priming session hrs 5-63.83.54.12.02.01.91.81.91.81.81.91.9-1.71.82.0
Progressive ratio0.30.41.1-0.5-0.5-1.0-1.0-0.6-0.9-1.0-0.3-0.30.0-0.2-0.3
Food seeking constrained by brief footshock0.10.10.20.00.0-0.4-0.5-0.2-0.3-0.4-0.0-0.00.5-0.20.2
Seeking ratio, punishment vs. effort0.71.11.81.01.01.31.31.01.31.30.80.9-0.50.80.9
Retroperitoneal fat weight0.41.73.7-1.8-1.9-1.0-1.0-1.4-1.2-1.1-1.1-1.20.9-1.1-1.2
Reaction time number correct0.81.61.9-1.4-1.4-1.2-1.2-1.3-1.2-1.2-1.2-1.31.2-1.3-1.4
Reaction time mean minus median1.12.73.61.91.91.51.51.81.61.41.61.6-1.91.71.3
Reaction time mean minus median AUC1.53.75.32.02.01.81.82.01.91.81.91.9-2.32.01.6
Reaction time num false alarms0.91.31.81.21.21.21.21.11.11.21.11.2-0.61.11.4
Reaction time num false alarms AUC0.91.52.11.31.31.21.21.21.21.21.21.2-0.71.21.4
Reaction time trials correct on left0.81.61.9-1.4-1.4-1.2-1.2-1.3-1.2-1.2-1.2-1.31.2-1.3-1.4
Reaction time trials on left0.81.51.8-1.3-1.3-1.2-1.2-1.3-1.2-1.2-1.2-1.31.2-1.2-1.3
Reaction time mean1.11.72.61.31.31.31.31.41.31.31.11.1-1.61.41.0
Reaction time mean AUC1.32.03.01.51.51.41.41.51.41.41.21.3-1.71.51.1
Median of all reaction times0.71.01.50.90.91.11.11.11.01.10.80.8-1.21.10.7
Reaction time omissions1.31.82.41.51.51.31.31.41.21.31.41.4-1.31.31.3
Reaction time false alarm rate1.62.33.11.61.61.51.51.51.41.51.51.6-1.01.51.8
Reaction time premature initiation rate0.20.30.91.01.00.30.30.50.30.30.50.5-0.20.40.4
Reaction time premature initiations0.00.00.10.30.3-0.2-0.2-0.1-0.2-0.2-0.0-0.10.3-0.2-0.2
Std. dev. reaction times1.42.73.41.81.81.61.61.81.61.61.51.5-1.81.61.3
Reaction time trials completed0.81.51.8-1.3-1.3-1.2-1.2-1.3-1.2-1.2-1.2-1.31.2-1.2-1.3
Reaction time trials AUC0.81.61.8-1.3-1.4-1.2-1.2-1.3-1.2-1.2-1.2-1.31.2-1.3-1.3
Run reversals in cocaine runway, females0.10.10.20.20.20.40.40.20.30.40.10.10.20.10.2
Run reversals in cocaine runway, males1.31.31.9-1.3-1.3-1.1-1.4-1.2-1.2-1.4-1.0-1.00.6-1.0-1.1
Latency to leave start box in cocaine runway4.75.47.4-2.4-2.4-2.3-2.4-2.2-2.1-2.4-2.4-2.41.7-2.1-2.7
Latency to leave start box in cocaine runway, F7.88.910.8-2.9-2.9-3.1-3.1-2.9-2.9-3.1-3.0-3.12.6-2.8-3.3
Latency to leave start box in cocaine runway, M0.10.10.3-0.4-0.40.10.00.00.20.0-0.2-0.1-0.50.2-0.3
Std. dev. time between licks in bursts1.11.51.7-1.1-1.1-1.3-1.3-1.3-1.3-1.3-1.1-1.11.1-1.3-1.1
Total sessions with >9 infusions0.00.00.00.20.2-0.2-0.2-0.1-0.2-0.2-0.2-0.20.1-0.0-0.2
Short access day 1 total inactive lever presses0.20.30.50.40.50.40.50.50.70.50.70.6-0.60.50.4
Short access day 10 total inactive lever presses0.71.72.4-1.6-1.5-1.3-1.2-1.4-1.2-1.2-1.2-1.21.1-1.3-1.3
Short access day 1 total infusions0.10.10.20.00.0-0.4-0.3-0.2-0.3-0.3-0.2-0.30.4-0.2-0.4
Short access day 10 total infusions0.00.00.0-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.10.1-0.2
Short access total infusions0.20.20.4-0.3-0.3-0.6-0.6-0.5-0.5-0.5-0.5-0.50.5-0.4-0.6
Short access day 1 locomotion0.30.40.5-0.7-0.7-0.7-0.7-0.7-0.6-0.6-0.7-0.70.5-0.6-0.6
Short access day 10 total locomotion0.00.00.0-0.1-0.2-0.1-0.1-0.1-0.2-0.1-0.2-0.1-0.0-0.0-0.1
Short access total locomotion0.20.20.3-0.4-0.4-0.5-0.5-0.5-0.4-0.4-0.5-0.50.4-0.4-0.4
One hour access (0.3 mA shock)0.70.81.00.50.60.91.00.81.00.90.90.9-1.00.90.9
Compulsive drug intake2.83.43.81.91.91.81.81.91.91.81.81.8-1.61.71.9
One hour access (shock baseline)0.50.81.6-1.3-1.2-0.8-0.7-1.0-0.8-0.8-0.9-0.90.6-0.7-0.9
Social response proportion2.63.03.51.81.91.81.81.71.91.81.71.7-1.51.61.6
Social responses0.00.00.10.20.2-0.0-0.00.10.10.00.20.10.2-0.00.2
Social time0.10.20.4-0.3-0.3-0.5-0.5-0.5-0.6-0.5-0.2-0.20.6-0.40.0
Soleus weight1.74.95.4-2.3-2.3-2.1-2.2-2.2-2.2-2.1-2.3-2.32.2-2.2-2.1
Bone: stiffness0.00.10.3-0.5-0.6-0.0-0.0-0.1-0.0-0.0-0.2-0.2-0.2-0.0-0.2
Tibialis anterior weight0.00.10.30.30.30.20.20.20.20.30.40.3-0.00.20.6
Time to tail flick, vehicle, before self-admin3.43.53.81.91.91.91.91.91.91.91.81.8-1.92.01.9
Time to tail flick, vehicle, after self-admin0.91.32.1-1.5-1.5-0.9-0.9-1.2-0.9-0.9-1.1-1.10.8-1.1-1.3
Time to tail flick, test, before self-admin0.50.50.9-0.7-0.7-0.7-0.6-0.6-0.7-0.6-0.9-0.90.9-0.5-0.8
Time to tail flick, test, after self-admin1.01.01.3-1.0-1.0-1.0-0.9-1.0-1.1-0.9-1.1-1.11.0-1.0-1.1
Delta time to tail flick, vehicle, before/after SA6.05.86.5-2.5-2.5-2.3-2.3-2.5-2.3-2.3-2.3-2.32.4-2.5-2.4
Delta time to tail flick, test, before/after SA0.30.30.50.70.70.40.40.50.50.40.60.6-0.60.30.6
Tibia length0.82.23.2-1.8-1.8-1.4-1.4-1.5-1.4-1.4-1.5-1.51.2-1.4-1.6
Ambulatory time before self-admin0.71.11.50.50.51.21.20.91.01.21.11.1-1.21.01.1
Ambulatory time after self-admin0.00.10.3-0.5-0.50.10.1-0.10.20.1-0.1-0.00.2-0.00.0
Bone: tissue strength1.31.31.9-1.3-1.4-1.2-1.2-1.2-1.1-1.2-1.1-1.20.9-1.0-1.2
Total heroin consumption0.81.01.61.21.20.90.90.90.90.91.11.1-0.80.81.3
Bone: trabecular number0.10.20.7-0.7-0.8-0.4-0.4-0.5-0.4-0.4-0.4-0.40.1-0.4-0.4
Bone: trabecular spacing0.00.00.10.10.2-0.1-0.1-0.0-0.2-0.10.10.10.3-0.10.1
Bone: trabecular thickness4.45.67.2-2.4-2.4-2.3-2.3-2.3-2.2-2.3-2.4-2.52.3-2.2-2.7
Bone: trabecular tissue density0.00.00.00.20.20.10.10.1-0.00.1-0.0-0.00.10.1-0.1
Water consumed over 24 hours0.10.10.20.50.50.10.10.30.10.10.20.2-0.10.30.3
Number of responses in last shaping day1.11.21.6-1.3-1.2-1.0-1.0-1.1-1.0-0.9-1.2-1.21.0-1.0-1.1