Hub : Genes

LOC120095180

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC120095180 0.03 0.03 2.1e-03 0.01 0.01 0.01 0.01 2.8e-02 2.2e-02 4.6e-02 4.6e-02
2 PL mRNA stability LOC120095180 0.04 0.04 1.7e-03 0.01 0.02 0.01 0.01 1.2e-02 2.1e-03 3.9e-02 1.4e-02
3 IL gene expression LOC120095180 0.54 0.19 4.7e-09 0.28 0.26 0.26 0.3 1.6e-07 8.0e-07 4.7e-07 7.4e-08
4 PL gene expression LOC120095180 0.47 0.11 0.0e+00 0.53 0.52 0.52 0.53 3.9e-68 1.3e-66 2.5e-67 7.0e-69
5 pVTA gene expression LOC120095180 0.24 0.11 6.0e-12 0.27 0.2 0.25 -0 5.8e-12 4.0e-09 4.2e-11 4.1e-01
6 Brain gene expression LOC120095180 0.54 0.22 0.0e+00 0.37 0.35 0.36 0.36 1.1e-35 1.6e-33 2.2e-34 4.1e-35
7 OFC gene expression LOC120095180 0.34 0.16 2.5e-07 0.25 0.22 0.2 0.27 9.7e-07 7.4e-06 2.0e-05 3.3e-07
8 LHb gene expression LOC120095180 0.18 0.12 1.3e-03 0.09 0.1 0.08 0.08 4.3e-03 2.8e-03 6.8e-03 7.2e-03
9 NAcc gene expression LOC120095180 0.63 0.09 0.0e+00 0.47 0.48 0.47 0.48 8.2e-61 4.8e-63 1.7e-60 3.0e-62
10 BLA gene expression LOC120095180 0.22 0.11 4.2e-14 0.21 0.22 0.2 0.2 3.0e-11 9.1e-12 7.2e-11 5.0e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.11.82.31.4-1.4-1.5-1.31.31.5-1.3-1.3-1.1-1.3
Area under the delay curve0.00.00.1-0.20.30.00.0-0.1-0.00.10.10.10.0
BMI with tail17.255.675.48.6-8.7-7.4-7.17.17.3-6.9-7.3-7.0-7.0
BMI without tail0.81.63.41.8-1.9-1.2-1.01.01.1-1.0-1.2-1.0-1.0
Body weight0.83.44.41.8-1.8-2.1-1.81.71.9-1.7-2.0-1.7-1.9
Weight adjusted by age0.10.10.2-0.40.50.20.2-0.2-0.00.40.30.10.3
Bone surface0.30.50.70.5-0.6-0.9-0.60.60.8-0.6-0.7-0.7-0.7
Bone volume0.81.31.80.9-1.0-1.3-1.11.11.3-1.1-1.2-1.1-1.3
Breakpoint value in progressive ratio session2.72.94.0-1.71.81.61.7-1.5-2.01.41.81.71.8
Number of licking bursts0.91.11.5-0.70.61.21.1-1.2-1.01.21.11.01.1
Context. condit. distance diff. score1.01.21.51.2-1.2-1.2-1.11.01.2-1.0-1.1-1.1-1.1
Locomotion velocity, session 10.00.00.10.1-0.10.20.2-0.1-0.20.10.20.10.3
Locomotion distance, session 14.96.26.7-2.52.52.52.5-2.5-2.62.52.52.52.5
Locomotion velocity, session 21.31.52.5-1.61.61.11.1-1.1-1.21.11.11.01.0
Locomotion distance, session 26.38.89.7-2.82.83.13.0-2.9-3.12.93.02.93.1
Locomotion velocity, session 30.40.50.70.4-0.3-0.8-0.70.70.5-0.7-0.8-0.7-0.8
Locomotion distance, session 31.31.51.7-1.21.31.11.2-1.1-1.31.11.21.31.2
Stereotopy head waving bouts, day 34.04.75.22.2-2.1-2.3-2.12.22.0-2.2-2.3-2.1-2.2
Stereotopy head waving duration, day 33.03.64.01.7-1.7-2.0-1.91.91.9-1.9-2.0-1.9-2.0
Locomotion velocity, session 71.51.62.1-1.51.41.21.3-1.3-1.11.31.11.31.0
Locomotion distance, session 77.08.99.7-3.13.03.03.1-3.1-2.83.12.83.12.7
Stereotopy head waving bouts, day 70.40.50.60.7-0.6-0.7-0.80.80.5-0.8-0.7-0.8-0.7
Stereotopy head waving duration, day 70.30.40.50.5-0.4-0.6-0.70.70.3-0.7-0.6-0.7-0.6
Locomotion velocity, session 80.81.01.31.0-0.9-1.0-1.01.10.9-1.1-0.9-1.1-0.8
Locomotion distance, session 80.50.70.9-0.70.70.80.8-0.8-0.90.80.90.81.0
Degree of sensitization distance0.20.20.4-0.60.50.50.5-0.6-0.30.60.40.50.3
Degree of sensitization stereotypy0.20.20.3-0.20.30.50.4-0.4-0.60.40.50.40.5
Conditioned locomotion2.12.53.41.5-1.6-1.4-1.71.51.8-1.5-1.5-1.7-1.5
Cocaine response after cond. corrected6.47.29.23.0-3.0-2.7-2.62.62.6-2.6-2.5-2.7-2.4
Cocaine response after cond. not corrected3.74.15.42.3-2.3-2.0-2.02.01.9-2.0-1.9-2.0-1.8
Cocaine response before conditioning2.93.53.9-1.92.01.91.9-1.8-1.91.81.81.81.8
Saline control response0.10.20.80.7-0.9-0.1-0.40.30.4-0.2-0.1-0.4-0.2
Bone: connectivity density0.20.30.60.7-0.6-0.8-0.50.50.7-0.5-0.5-0.3-0.5
Bone: cortical apparent density5.26.88.4-2.92.92.62.6-2.6-2.72.62.52.52.4
Bone: cortical area0.30.50.70.5-0.6-0.7-0.70.70.9-0.7-0.7-0.7-0.8
Bone: cortical porosity0.30.30.40.6-0.6-0.6-0.50.50.6-0.5-0.6-0.5-0.6
Bone: cortical porosity0.20.20.30.4-0.5-0.4-0.40.40.5-0.4-0.4-0.3-0.5
Bone: cortical thickness0.10.20.40.2-0.2-0.5-0.50.50.6-0.5-0.5-0.5-0.6
Bone: cortical thickness0.50.51.0-0.70.90.50.7-0.7-0.50.70.71.00.7
Bone: cortical tissue density5.77.59.2-3.03.02.72.7-2.7-2.82.72.62.62.5
Condit. Reinf. active minus inactive responses1.21.41.8-1.00.91.31.3-1.4-1.11.41.11.21.1
Condit. Reinf. active-inactive response ratio0.00.00.20.4-0.4-0.0-0.0-0.00.20.0-0.10.1-0.1
Condit. Reinf. active responses1.31.62.0-1.11.01.41.3-1.4-1.31.41.21.21.3
Condit. Reinf. inactive responses1.01.21.9-1.01.01.21.0-1.1-1.41.11.20.91.2
Incentive salience index mean2.02.42.9-1.31.31.71.6-1.7-1.51.71.61.61.6
Condit. Reinf. lever presses2.43.13.9-1.51.42.01.8-1.8-1.91.81.91.72.0
Condit. Reinf. active minus inactive responses0.20.20.3-0.10.10.50.5-0.5-0.50.50.50.60.5
Condit. Reinf. active-inactive response ratio0.30.30.60.3-0.30.50.6-0.6-0.50.50.60.50.8
Condit. Reinf. active responses0.10.20.4-0.30.30.40.5-0.5-0.40.40.40.60.4
Condit. Reinf. inactive responses0.00.00.1-0.30.4-0.1-0.10.00.1-0.0-0.10.1-0.2
Condit. Reinf. lever presses0.40.51.3-1.11.10.50.6-0.6-0.70.50.70.70.6
Condit. Reinf. lever reinforcers received0.20.20.4-0.40.40.40.5-0.5-0.40.50.50.70.4
Conditioned reinforcement - actives0.20.20.5-0.20.10.60.4-0.6-0.50.70.40.50.5
Conditioned reinforcement - inactives0.10.10.2-0.20.00.40.2-0.4-0.10.50.30.30.2
Conditioned locomotion0.20.20.70.7-0.8-0.2-0.60.40.3-0.3-0.3-0.5-0.3
Patch foraging indifference point 0 sec1.52.53.11.5-1.4-1.7-1.61.61.8-1.6-1.5-1.7-1.5
Patch foraging indifference point AUC0.10.10.1-0.30.40.30.2-0.4-0.20.30.20.40.1
Delay disc. indifference point, 0s delay0.00.00.1-0.10.0-0.2-0.30.20.3-0.2-0.0-0.2-0.2
Delay disc. indifference point, 16s delay1.11.11.21.0-0.9-1.1-1.11.01.0-1.0-1.1-1.0-1.1
Delay disc. indifference point, 2s delay0.10.10.4-0.60.50.20.2-0.2-0.00.30.30.20.1
Delay disc. indifference point, 24s delay0.90.81.1-0.90.90.90.9-0.9-0.91.10.90.90.9
Delay disc. indifference point, 4s delay1.21.32.6-1.51.60.81.1-0.9-0.90.91.01.30.9
Delay disc. indifference point, 8s delay0.10.10.1-0.30.40.30.3-0.4-0.30.40.30.30.3
Indifference point function ln k0.00.00.0-0.10.10.10.10.0-0.10.00.20.10.2
Indifference point function log k0.00.00.0-0.10.10.10.10.0-0.10.00.20.10.2
Patch foraging total patch changes 0 sec1.72.83.41.5-1.5-1.7-1.71.71.9-1.6-1.6-1.8-1.6
Patch foraging total patch changes 12 sec0.00.00.10.2-0.3-0.2-0.20.00.3-0.0-0.2-0.3-0.3
Patch foraging total patch changes 18 sec2.43.13.71.7-1.7-1.9-1.71.81.9-1.8-1.7-1.7-1.8
Patch foraging total patch changes 24 sec1.21.41.71.2-1.1-1.2-1.21.11.3-1.2-1.2-1.2-1.2
Patch foraging total patch changes 6 sec0.91.41.91.2-1.1-1.2-1.10.91.4-1.0-1.2-1.2-1.3
Patch foraging time to switch 0 sec0.10.10.3-0.20.20.40.4-0.4-0.20.60.40.30.4
Patch foraging water rate 0 sec1.82.93.31.7-1.6-1.8-1.71.61.6-1.8-1.7-1.5-1.7
Patch foraging water rate 12 sec0.50.81.30.8-0.7-1.1-0.91.00.7-1.1-1.0-0.7-1.0
Patch foraging water rate 18 sec0.00.00.00.0-0.1-0.0-0.1-0.10.0-0.1-0.1-0.1-0.1
Patch foraging water rate 24 sec1.52.12.31.5-1.5-1.5-1.41.51.4-1.5-1.4-1.4-1.4
Patch foraging water rate 6 sec0.10.20.60.7-0.6-0.4-0.30.40.2-0.5-0.2-0.1-0.1
Seeking ratio, delayed vs. immediate footshock1.82.13.01.2-1.4-1.4-1.41.41.6-1.3-1.4-1.7-1.5
Distance traveled before self-admin2.72.93.6-1.31.21.71.8-1.8-1.61.91.81.91.9
Distance traveled after self-admin0.20.21.01.0-0.9-0.4-0.20.30.3-0.3-0.20.1-0.1
Extensor digitorum longus weight0.83.03.81.5-1.5-1.9-1.81.71.9-1.7-1.9-1.6-1.9
Bone: elastic displacement0.00.00.10.3-0.3-0.2-0.10.10.3-0.1-0.10.0-0.1
Bone: elastic work0.00.00.00.0-0.1-0.2-0.10.10.2-0.1-0.00.0-0.1
Bone: endosteal estimation0.00.00.00.0-0.1-0.2-0.20.10.1-0.1-0.1-0.1-0.2
Bone: endosteal perimeter0.10.20.30.4-0.5-0.5-0.50.50.6-0.5-0.5-0.6-0.5
Epididymis fat weight0.10.10.30.4-0.5-0.5-0.20.20.4-0.3-0.40.1-0.4
Delta time in closed arm before/after self-admin0.10.10.2-0.1-0.0-0.3-0.30.30.4-0.3-0.4-0.4-0.4
Delta time in open arm before/after self-admin0.00.00.0-0.10.2-0.0-0.0-0.00.0-0.00.1-0.10.1
Diff in mean of infusions in LGA sessions1.51.62.2-1.21.11.21.3-1.1-1.31.01.41.41.5
Delay discount exponential model param0.10.10.20.4-0.4-0.2-0.20.20.2-0.3-0.3-0.3-0.2
Extinction: sum of active levers before priming1.41.42.5-1.61.51.01.3-1.3-0.81.11.11.20.9
Active lever presses in extinction session 60.10.10.20.4-0.2-0.4-0.20.20.1-0.4-0.2-0.0-0.1
Bone: final force0.10.10.30.4-0.5-0.4-0.30.30.4-0.3-0.3-0.2-0.3
Bone: final moment0.20.30.50.6-0.7-0.5-0.50.50.6-0.5-0.5-0.4-0.5
Food consumed during 24 hour testing period2.02.52.6-1.61.61.61.6-1.6-1.51.61.51.61.5
Glucose0.81.21.70.7-0.8-1.2-1.11.11.1-1.1-1.3-1.2-1.3
Heart weight0.91.21.71.0-1.2-1.1-1.00.81.3-0.9-1.2-1.0-1.3
Delay discount hyperbolic model param0.10.10.30.5-0.6-0.2-0.30.30.2-0.4-0.3-0.4-0.3
Intermittent access intake day 1-15 change1.01.01.51.2-1.2-1.0-1.00.91.0-0.9-0.9-1.0-0.8
Intermittent access intake escalation0.50.50.70.9-0.8-0.7-0.70.60.7-0.6-0.6-0.7-0.5
Intermittent access intake escalation 20.90.91.61.3-1.2-0.9-1.00.90.8-0.9-0.7-0.9-0.6
Intermitt. access day 1 inactive lever presses0.00.00.20.4-0.40.00.0-0.0-0.10.10.10.10.1
Intermitt. access day 15 inactive lever presses1.71.82.21.2-1.1-1.5-1.41.31.4-1.4-1.4-1.3-1.4
Intermitt. access escalation Index0.10.10.2-0.20.20.30.3-0.2-0.50.20.40.20.5
Intermittent access day 1 total infusions1.21.41.9-1.41.21.31.2-1.2-1.21.41.01.10.9
Intermittent access day 15 total infusions0.50.61.0-0.80.70.80.7-0.9-0.71.00.70.70.7
Intermittent access terminal intake (last 3 days)0.20.20.5-0.40.30.50.4-0.6-0.40.70.40.50.4
Intermittent access total infusions0.30.40.8-0.70.60.60.6-0.7-0.50.90.50.60.4
Intermittent access day 1 locomotion2.62.73.2-1.81.71.71.6-1.7-1.71.71.51.51.5
Intermittent access day 15 total locomotion0.60.70.9-0.90.80.80.8-0.9-0.71.00.70.80.7
Intermittent access total locomotion0.81.01.3-1.10.91.01.0-1.1-1.01.10.91.00.8
Intermittent access standard deviation0.90.91.11.0-1.1-1.0-1.00.91.1-0.9-0.9-0.8-0.9
Left kidney weight0.00.00.2-0.50.4-0.0-0.0-0.1-0.00.1-0.1-0.0-0.2
Right kidney weight0.51.52.00.6-0.7-1.4-1.41.31.1-1.4-1.3-1.4-1.4
Cocaine induced anxiety0.00.00.20.3-0.40.0-0.20.10.0-0.10.1-0.10.1
Post-drug Anxiety1.01.11.4-0.80.71.21.0-1.1-1.01.21.21.01.2
Baseline Anxiety0.00.00.0-0.10.1-0.10.1-0.10.20.0-0.10.1-0.1
Tail length17.151.665.6-8.18.17.07.0-7.1-7.17.06.96.96.6
Length with tail8.631.449.0-6.97.05.15.3-5.4-5.45.25.25.34.8
Length without tail0.10.10.5-0.70.7-0.3-0.00.00.1-0.1-0.2-0.0-0.3
Times rat made contact with spout0.70.81.0-0.90.81.00.9-0.9-1.00.90.90.80.8
Lifetime Intake0.40.40.7-0.80.70.70.5-0.7-0.60.80.60.60.5
Liver weight, left1.11.72.4-1.41.51.21.3-1.3-1.21.31.21.51.1
Liver weight, right0.81.32.8-1.71.60.81.1-1.1-0.81.10.81.30.6
Locomotor activity0.20.31.21.1-1.1-0.3-0.40.30.4-0.3-0.4-0.3-0.2
Locomotor testing distance0.50.82.41.6-1.5-0.6-0.70.60.9-0.5-0.6-0.6-0.4
Locomotor testing rearing0.20.21.01.0-1.0-0.2-0.30.10.5-0.1-0.1-0.10.0
Locomotion in novel chamber0.10.20.3-0.20.10.30.4-0.5-0.40.50.50.50.5
Locomotion in novel chamber post-restriction1.41.62.31.2-1.5-1.2-1.41.11.4-1.2-1.1-1.3-1.2
Fecal boli incidents, locomotor time 13.13.43.92.0-1.8-1.9-1.81.71.8-1.9-1.9-1.7-1.8
Change in fecal boli incidents, locomotor task2.32.22.6-1.61.51.41.5-1.5-1.51.51.41.61.4
Time >=10cm from walls, locomotor time 10.10.10.20.3-0.30.20.2-0.3-0.00.20.40.20.4
Bouts of movement, locomotor time 10.20.20.40.1-0.1-0.6-0.40.50.3-0.5-0.6-0.6-0.7
Total resting periods, locomotor time 10.60.61.00.4-0.4-0.9-0.80.80.5-0.9-0.9-0.9-1.0
Rest time, locomotor task time 10.10.20.30.2-0.2-0.4-0.50.40.4-0.5-0.4-0.5-0.4
Distance moved, locomotor task time 12.52.83.4-1.41.41.71.8-1.7-1.61.81.71.81.7
Vertical activity count, locomotor time 10.60.71.1-0.50.50.91.0-0.9-0.71.10.70.90.8
Time >=10cm from walls, locomotor time 20.40.40.6-0.40.40.70.7-0.7-0.50.70.70.70.7
Bouts of movement, locomotor time 20.00.00.20.1-0.2-0.1-0.2-0.10.50.2-0.1-0.3-0.2
Total resting periods, locomotor time 20.10.10.30.2-0.3-0.1-0.3-0.10.50.1-0.1-0.4-0.2
Rest time, locomotor task time 20.20.30.5-0.60.60.60.3-0.3-0.70.30.60.30.6
Distance moved, locomotor task time 20.30.40.7-0.70.80.40.8-0.8-0.50.60.40.70.4
Vertical activity count, locomotor time 20.30.30.7-0.40.40.40.7-0.8-0.10.80.30.50.3
Light reinforcement 10.10.10.50.7-0.6-0.2-0.20.10.1-0.1-0.1-0.20.1
Light reinforcement 20.30.40.7-0.40.40.70.6-0.6-0.70.60.80.50.9
Bone: marrow area0.00.00.0-0.1-0.0-0.1-0.10.00.0-0.0-0.0-0.0-0.0
Bone: maximum diameter0.20.40.50.6-0.7-0.6-0.60.60.7-0.6-0.6-0.7-0.6
Bone: maximum force0.50.91.10.8-0.9-1.1-1.01.01.0-1.0-1.0-0.9-1.0
Bone: maximum moment0.71.21.40.9-1.0-1.2-1.11.11.1-1.1-1.1-1.1-1.1
Mean time between licks in bursts0.81.21.80.7-0.8-1.0-1.11.11.1-1.2-1.2-1.2-1.3
Mean num. licks in bursts0.10.10.2-0.20.2-0.3-0.30.40.2-0.3-0.3-0.3-0.4
Cd content in liver0.20.20.40.3-0.40.40.4-0.4-0.30.40.50.40.6
Co content in liver0.00.00.20.4-0.50.0-0.10.0-0.0-0.0-0.0-0.10.1
Cu content in liver10.813.114.6-3.43.33.73.7-3.8-3.63.83.53.63.6
Fe content in liver2.22.62.9-1.71.61.61.6-1.7-1.61.71.61.61.5
K content in liver1.21.22.3-1.51.31.01.1-1.2-0.81.20.80.90.7
Mg content in liver3.73.85.5-2.32.11.92.0-2.1-1.52.11.71.81.6
Mn content in liver3.64.14.8-2.12.22.11.9-1.9-1.91.92.11.82.1
Na content in liver0.70.81.3-1.11.00.90.9-1.0-0.61.00.70.80.6
Rb content in liver0.20.20.9-0.10.10.40.3-0.4-0.90.40.40.30.5
Se content in liver0.10.20.30.4-0.5-0.4-0.30.30.6-0.3-0.3-0.5-0.3
Sr content in liver0.80.71.7-1.31.30.70.8-0.8-0.50.80.70.80.6
Zn content in liver0.20.20.5-0.30.10.40.6-0.7-0.20.70.50.40.5
Bone: minimum diameter0.00.00.1-0.30.2-0.0-0.10.00.1-0.0-0.2-0.1-0.3
Time in familiar zone, hab. session 10.10.10.20.0-0.10.30.2-0.4-0.10.40.40.20.4
Time in novel zone, hab. session 12.12.02.61.2-1.1-1.6-1.41.51.3-1.5-1.6-1.3-1.6
Total zone transitions, hab. session 16.69.39.9-2.82.83.23.1-3.1-3.13.13.13.13.1
Total locomotion distance, hab. session 14.36.16.6-2.22.22.52.6-2.6-2.42.62.52.62.5
Locomotion velocity, hab. session 15.47.68.1-2.62.52.82.8-2.8-2.72.82.82.82.8
Time in familiar zone, hab. session 21.51.52.21.5-1.4-1.2-1.21.31.1-1.3-1.2-1.1-1.1
Time in novel zone, hab. session 20.20.20.3-0.60.50.40.4-0.5-0.30.50.50.40.4
Total zone transitions, hab. session 24.45.76.4-2.22.22.52.4-2.3-2.52.32.52.42.5
Total locomotion distance, hab. session 21.11.51.7-1.11.11.31.3-1.2-1.31.21.21.31.2
Locomotion velocity, hab. session 21.41.82.1-1.31.31.41.4-1.4-1.41.41.31.41.3
Novel to familiar place preference ratio0.30.40.8-0.30.40.40.7-0.7-0.30.70.60.90.6
Novelty place preference0.30.30.7-0.20.30.40.6-0.6-0.20.60.50.80.6
Time in novel zone, NPP test0.10.10.50.00.10.20.5-0.5-0.10.50.30.70.4
Total zone transitions, NPP test5.67.99.1-2.62.63.02.8-2.7-2.92.73.02.83.0
Total locomotion distance, NPP test2.02.83.2-1.51.51.71.8-1.7-1.61.71.81.71.8
Locomotion velocity, NPP test2.73.84.0-2.01.92.02.0-1.9-1.81.92.02.01.9
Intraocular pressure1.21.72.2-1.31.31.21.3-1.2-1.31.21.41.51.3
Delta distance traveled before/after self-admin3.13.43.81.9-1.9-1.9-1.81.81.7-1.9-1.8-1.7-1.8
Delta ambulatory time before/after self-admin3.03.33.92.0-1.9-1.9-1.71.81.7-1.9-1.9-1.7-1.8
Parametrial fat weight0.20.40.7-0.30.30.60.7-0.8-0.60.80.60.60.7
Pavlov. Cond. lever latency1.31.62.30.7-0.7-1.4-1.31.31.3-1.3-1.4-1.3-1.5
Pavlov. Cond. magazine entry latency0.20.20.40.1-0.00.50.5-0.5-0.50.50.50.60.6
Pavlov. Cond. change in total contacts3.63.84.8-1.51.52.12.0-2.0-2.02.02.12.02.2
Pavlov. Cond. index score0.81.11.7-0.40.41.21.1-1.1-1.11.11.21.11.3
Pavlov. Cond. latency score0.81.11.7-0.40.51.21.1-1.1-1.11.11.21.11.3
Pavlov. Cond. lever contacts2.22.53.6-1.11.11.81.6-1.6-1.61.61.81.61.9
Pavlov. Cond. magazine entry number0.60.81.20.4-0.4-0.9-1.00.90.8-0.9-0.9-1.1-1.0
Pavlov. Cond. intertrial magazine entries1.21.52.0-1.41.21.31.2-1.3-1.31.31.11.01.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.5-0.30.41.00.9-1.0-1.01.01.11.01.2
Pavlov. Cond. response bias0.70.81.4-0.30.41.01.0-0.9-0.90.91.11.11.2
Pavlov. Cond. lever latency1.82.53.1-1.21.11.71.8-1.7-1.51.71.61.71.7
Pavlov. Cond. magazine entry latency0.50.61.7-1.31.30.60.5-0.5-0.70.50.50.40.4
Pavlov. Cond. change in total contacts0.50.71.00.4-0.3-0.9-1.00.90.8-0.9-0.8-0.9-0.9
Pavlov. Cond. index score0.40.60.80.2-0.2-0.8-0.90.90.7-0.8-0.8-0.9-0.9
Pavlov. Cond. latency score0.20.30.4-0.10.1-0.5-0.60.60.4-0.6-0.5-0.7-0.6
Pavlov. Cond. lever contacts1.31.82.31.0-1.0-1.4-1.51.41.3-1.4-1.3-1.5-1.4
Pavlov. Cond. magazine entry number0.10.20.40.7-0.60.20.3-0.3-0.10.30.30.30.5
Pavlov. Cond. intertrial magazine entries1.82.33.0-1.01.01.51.7-1.7-1.41.71.61.71.7
Pavlov. Cond. lever-magazine prob. diff.0.60.71.10.3-0.2-0.9-1.01.00.8-1.0-0.9-1.0-1.0
Pavlov. Cond. response bias0.91.21.60.7-0.6-1.1-1.31.21.0-1.2-1.1-1.2-1.2
Time in closed arm before self-admin2.62.93.71.7-1.7-1.8-1.61.71.9-1.6-1.8-1.4-1.9
Time in closed arm after self-admin2.62.63.91.3-1.4-1.7-1.51.41.9-1.4-1.9-1.5-2.0
Time in open arm before self-admin0.40.40.6-0.50.50.70.6-0.7-0.70.60.70.60.8
Time in open arm after self-admin0.20.30.5-0.40.50.50.5-0.5-0.60.30.70.40.7
Bone: periosteal estimation0.20.50.50.6-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7
Bone: periosteal perimeter0.91.51.81.2-1.2-1.2-1.21.21.3-1.2-1.2-1.3-1.2
Bone: post-yield work0.70.91.20.7-0.7-1.0-1.01.10.9-1.1-1.0-1.0-1.1
Progressive ratio test 1 active lever presses1.01.11.5-0.90.91.21.0-1.1-1.01.21.10.91.1
Progressive ratio test 1 breakpoint1.21.21.7-1.00.91.21.0-1.2-1.01.31.11.01.1
Progressive ratio test 1 inactive lever presses0.40.50.91.0-0.9-0.6-0.70.60.6-0.7-0.5-0.6-0.4
Progressive ratio test 2 active lever presses1.41.52.4-1.00.81.31.3-1.4-1.11.61.21.41.2
Progressive ratio test 2 breakpoint0.80.91.6-0.60.51.01.0-1.1-0.81.30.91.10.9
Progressive ratio test 2 inactive lever presses0.00.00.2-0.0-0.10.20.2-0.3-0.10.40.10.20.1
Incentive Sensitization - Responses0.30.30.8-0.20.00.50.7-0.7-0.20.90.40.80.4
Incentive Sensitization - Breakpoint0.10.10.40.1-0.20.20.5-0.50.10.60.20.60.2
Sum of active levers in priming session hrs 5-65.95.76.8-2.52.62.32.4-2.3-2.52.22.32.42.3
Progressive ratio0.30.40.90.8-1.0-0.2-0.80.40.6-0.2-0.3-0.9-0.3
Food seeking constrained by brief footshock0.10.10.30.6-0.5-0.2-0.30.4-0.0-0.4-0.1-0.2-0.0
Seeking ratio, punishment vs. effort0.80.91.5-1.01.20.71.1-0.8-1.10.60.81.20.8
Retroperitoneal fat weight0.20.61.00.8-0.8-0.8-0.80.61.0-0.6-0.8-0.6-0.8
Reaction time number correct1.42.12.61.2-1.2-1.4-1.61.61.4-1.6-1.4-1.4-1.6
Reaction time mean minus median2.43.24.3-2.12.01.71.7-1.9-1.52.01.71.61.6
Reaction time mean minus median AUC3.44.45.6-2.42.32.02.1-2.2-1.92.22.01.92.0
Reaction time num false alarms0.81.11.7-0.70.81.21.1-1.1-1.31.01.01.01.1
Reaction time num false alarms AUC0.81.21.6-0.80.91.21.1-1.1-1.31.01.11.11.2
Reaction time trials correct on left1.42.12.61.2-1.2-1.4-1.61.61.4-1.6-1.4-1.4-1.6
Reaction time trials on left1.41.92.51.1-1.1-1.4-1.51.51.4-1.6-1.4-1.3-1.5
Reaction time mean1.62.33.0-1.71.71.41.5-1.6-1.31.71.31.41.3
Reaction time mean AUC2.02.63.4-1.91.81.51.7-1.8-1.41.81.41.51.4
Median of all reaction times0.70.91.3-1.11.10.91.0-1.1-0.81.10.80.90.8
Reaction time omissions1.01.41.6-1.21.21.21.1-1.1-1.31.11.31.01.3
Reaction time false alarm rate1.62.32.8-1.11.21.61.6-1.6-1.71.61.51.51.7
Reaction time premature initiation rate0.10.20.3-0.40.50.40.3-0.2-0.50.30.60.40.6
Reaction time premature initiations0.10.10.30.00.0-0.2-0.40.60.2-0.5-0.1-0.2-0.2
Std. dev. reaction times2.53.54.8-2.22.21.81.9-1.9-1.72.01.71.71.6
Reaction time trials completed1.41.92.51.1-1.1-1.4-1.51.51.4-1.6-1.4-1.3-1.5
Reaction time trials AUC1.42.02.51.2-1.2-1.4-1.51.61.4-1.6-1.4-1.3-1.5
Run reversals in cocaine runway, females0.20.20.5-0.60.70.30.4-0.3-0.50.20.30.60.3
Run reversals in cocaine runway, males1.51.52.51.4-1.6-1.0-1.31.11.3-0.9-1.1-1.3-1.1
Latency to leave start box in cocaine runway4.54.97.01.8-1.9-2.3-2.22.12.7-1.8-2.4-2.2-2.5
Latency to leave start box in cocaine runway, F8.18.910.42.5-2.6-3.1-3.03.13.2-2.8-3.1-3.1-3.2
Latency to leave start box in cocaine runway, M0.10.10.3-0.0-0.10.00.2-0.30.40.5-0.10.2-0.1
Std. dev. time between licks in bursts0.91.11.51.0-1.0-1.0-1.11.20.9-1.2-1.0-1.1-1.0
Total sessions with >9 infusions0.80.91.3-1.11.21.00.7-0.8-1.00.90.90.60.8
Short access day 1 total inactive lever presses0.10.20.4-0.50.60.30.3-0.3-0.30.20.50.40.4
Short access day 10 total inactive lever presses0.40.40.70.8-0.8-0.7-0.70.60.7-0.6-0.6-0.6-0.6
Short access day 1 total infusions0.00.00.2-0.40.50.1-0.20.0-0.20.00.2-0.10.1
Short access day 10 total infusions0.10.20.4-0.60.50.50.3-0.4-0.30.60.20.20.1
Short access total infusions0.00.00.1-0.40.30.1-0.20.0-0.10.1-0.1-0.3-0.1
Short access day 1 locomotion0.00.00.1-0.10.10.0-0.20.1-0.2-0.1-0.1-0.3-0.1
Short access day 10 total locomotion1.01.11.4-1.11.01.11.1-1.1-1.21.11.01.01.0
Short access total locomotion0.20.20.5-0.60.50.50.3-0.3-0.70.30.30.10.2
One hour access (0.3 mA shock)0.81.01.4-0.80.71.00.9-1.1-0.91.20.91.10.9
Compulsive drug intake7.07.07.6-2.62.72.62.7-2.7-2.62.52.62.82.6
One hour access (shock baseline)1.11.22.11.3-1.5-0.9-1.11.01.3-0.8-1.0-1.1-1.0
Social response proportion2.32.53.3-1.51.61.61.7-1.4-1.51.51.61.81.6
Social responses0.10.10.30.6-0.4-0.00.00.20.0-0.20.10.30.2
Social time0.30.41.51.2-1.2-0.1-0.40.50.2-0.5-0.1-0.40.1
Soleus weight1.54.34.92.0-2.0-2.2-2.12.12.0-2.1-2.2-2.0-2.2
Bone: stiffness0.00.00.1-0.0-0.1-0.2-0.10.10.3-0.1-0.2-0.0-0.3
Tibialis anterior weight0.00.10.30.00.10.30.3-0.3-0.50.30.40.60.5
Time to tail flick, vehicle, before self-admin1.41.41.8-1.11.11.21.2-1.1-1.31.31.11.21.1
Time to tail flick, vehicle, after self-admin0.60.61.30.6-0.6-0.8-0.70.91.1-0.6-0.8-0.6-0.9
Time to tail flick, test, before self-admin0.40.40.80.5-0.4-0.5-0.60.50.7-0.2-0.9-0.6-0.9
Time to tail flick, test, after self-admin0.40.40.60.5-0.3-0.7-0.60.70.6-0.6-0.8-0.5-0.8
Delta time to tail flick, vehicle, before/after SA3.23.14.11.7-1.7-1.8-1.71.92.0-1.8-1.7-1.6-1.8
Delta time to tail flick, test, before/after SA0.30.30.5-0.50.50.40.4-0.4-0.70.20.60.60.7
Tibia length0.61.62.30.9-1.0-1.3-1.31.41.2-1.4-1.4-1.3-1.5
Ambulatory time before self-admin1.71.82.4-1.00.91.41.4-1.5-1.11.51.51.51.5
Ambulatory time after self-admin0.30.30.91.0-0.9-0.6-0.30.40.6-0.4-0.5-0.0-0.4
Bone: tissue strength1.00.91.40.6-0.7-1.0-1.01.01.0-1.0-1.0-1.0-1.2
Total heroin consumption0.30.40.6-0.40.60.60.6-0.4-0.80.50.70.70.8
Bone: trabecular number0.00.10.10.3-0.4-0.4-0.10.10.3-0.1-0.2-0.0-0.2
Bone: trabecular spacing0.10.20.60.8-0.7-0.1-0.30.50.2-0.5-0.1-0.30.0
Bone: trabecular thickness2.93.55.01.2-1.2-2.1-1.91.92.1-1.9-2.1-1.8-2.2
Bone: trabecular tissue density0.00.00.1-0.40.40.1-0.10.1-0.1-0.10.0-0.2-0.1
Water consumed over 24 hours0.00.00.0-0.20.20.20.1-0.1-0.10.10.20.10.2
Number of responses in last shaping day2.12.12.61.3-1.4-1.6-1.51.51.2-1.5-1.5-1.4-1.6