LOC120094772

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr9_113536021_113538070 0.04 0.03 2.7e-03 0.02 0.02 0.02 0.02 6.5e-04 8.7e-04 8.3e-04 8.3e-04
2 NAcc intron excision ratio chr9_113538217_113540485 0.02 0.02 1.0e-02 0.01 0.01 0.01 0.01 3.4e-02 3.3e-03 1.7e-02 5.7e-03
3 RMTg gene expression LOC120094772 0.18 0.12 1.9e-04 0.09 0.13 0.09 0.09 2.6e-03 3.1e-04 2.8e-03 2.1e-03
4 BLA isoform ratio XM_039084798.2 0.06 0.06 3.6e-03 0.01 0.02 0.01 0.01 1.4e-01 4.5e-02 8.1e-02 1.3e-01
5 BLA isoform ratio XR_005489407.2 0.05 0.05 9.6e-03 -0 0.01 0.01 0.01 4.3e-01 6.8e-02 1.0e-01 1.3e-01
6 pVTA gene expression LOC120094772 0.7 0.01 0.0e+00 0.26 0.34 0.37 0.37 7.3e-21 2.3e-28 4.5e-31 4.2e-31
7 Brain intron excision ratio chr9_113538217_113540485 0.04 0.03 2.0e-04 0.03 0.04 0.03 0.04 5.5e-04 8.9e-05 1.5e-03 2.7e-04
8 Eye gene expression LOC120094772 0.47 0.25 4.1e-03 0.06 0.02 0.01 0.02 3.9e-02 1.7e-01 2.1e-01 1.6e-01
9 BLA gene expression LOC120094772 0.17 0.14 3.0e-07 0.13 0.12 0.09 0.1 3.6e-07 1.2e-06 2.7e-05 3.8e-06
10 NAcc intron excision ratio chr9_113453567_113455067 0.02 0.01 4.0e-03 0.02 0.01 0.01 0.01 1.6e-03 1.1e-02 1.8e-02 2.4e-02
11 Brain gene expression LOC120094772 0.5 0.13 0.0e+00 0.39 0.48 0.48 0.48 1.8e-38 1.6e-49 1.7e-50 1.5e-50
12 LHb gene expression LOC120094772 0.54 0.16 4.9e-10 0.23 0.23 0.21 0.22 3.9e-06 3.4e-06 1.2e-05 7.1e-06
13 Adipose isoform ratio XR_005489407.2 0.08 0.04 1.3e-05 0.01 0.04 0.04 0.03 3.0e-02 3.5e-05 1.8e-05 1.5e-04
14 PL gene expression LOC120094772 0.41 0.2 0.0e+00 0.19 0.21 0.2 0.21 3.3e-20 4.1e-22 1.3e-21 1.4e-22
15 Adipose gene expression LOC120094772 0.15 0.07 1.0e-15 0.08 0.12 0.11 0.11 5.4e-09 4.7e-13 1.6e-12 1.3e-12
16 OFC gene expression LOC120094772 0.47 0.17 1.8e-06 0.15 0.2 0.22 0.19 2.1e-04 2.0e-05 5.3e-06 3.4e-05
17 Adipose isoform ratio XM_039084798.2 0.05 0.04 6.8e-04 0.01 0.03 0.02 0.02 2.7e-02 8.5e-04 4.3e-03 2.5e-03
18 Brain mRNA stability LOC120094772 0.1 0.06 3.4e-05 0.06 0.06 0.05 0.05 3.3e-06 3.6e-06 8.9e-06 8.4e-06
19 IL gene expression LOC120094772 0.54 0.15 1.8e-08 0.4 0.38 0.39 0.4 1.3e-10 3.0e-10 2.3e-10 1.5e-10
20 Liver isoform ratio XR_005489407.2 0.07 0.04 1.7e-05 0.04 0.04 0.04 0.04 1.6e-05 2.5e-05 3.0e-05 2.3e-05
21 NAcc gene expression LOC120094772 0.16 0.09 3.3e-11 0.07 0.07 0.06 0.07 1.6e-11 4.5e-11 1.1e-09 2.5e-11
22 NAcc isoform ratio XM_039084798.2 0.01 0.01 3.7e-03 0.02 0.01 0.02 0.01 1.2e-03 3.8e-03 4.0e-04 2.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.71.27.5-2.71.91.4-1.21.21.20.90.50.7-0.60.80.51.50.4-0.10.6-1.3-0.3-0.4-0.4-0.40.6
Area under the delay curve0.70.83.40.8-1.2-1.21.1-1.1-0.9-0.9-0.6-1.01.2-0.8-0.5-1.10.1-0.2-0.11.10.50.50.50.51.9
BMI with tail1.14.014.83.9-2.8-2.52.5-2.5-2.4-2.3-1.9-1.81.8-2.3-2.0-1.1-1.9-1.3-2.00.9-1.0-1.0-1.0-1.00.3
BMI without tail0.41.49.83.1-1.8-1.41.3-1.3-1.2-1.1-0.8-0.70.7-1.2-0.9-0.9-1.0-0.4-1.20.8-0.4-0.4-0.4-0.4-0.2
Body weight2.310.237.26.1-4.5-4.03.9-3.9-3.8-3.7-3.0-2.93.0-3.8-3.2-1.8-3.0-2.2-3.21.5-1.6-1.6-1.6-1.60.8
Weight adjusted by age0.30.41.1-0.3-0.1-0.30.3-0.3-0.5-0.6-1.1-0.60.4-0.7-0.70.2-0.7-0.8-0.2-0.6-0.8-0.8-0.8-0.80.9
Bone surface0.40.85.4-2.31.30.7-0.40.40.30.0-0.4-0.20.3-0.1-0.41.4-0.4-0.9-0.1-1.4-0.9-1.0-1.0-1.00.9
Bone volume0.61.07.0-2.71.71.2-1.01.01.00.70.30.5-0.40.60.31.50.2-0.30.4-1.4-0.5-0.5-0.5-0.50.6
Breakpoint value in progressive ratio session0.10.10.80.4-0.2-0.20.1-0.1-0.3-0.2-0.9-0.2-0.0-0.4-0.2-0.2-0.3-0.10.0-0.1-0.3-0.3-0.3-0.3-0.0
Number of licking bursts0.50.81.70.6-0.3-0.40.6-0.6-0.8-0.8-0.9-0.60.6-1.0-1.10.5-1.3-1.2-1.1-0.9-1.3-1.3-1.3-1.3-0.2
Context. condit. distance diff. score0.40.51.70.30.30.5-0.60.60.50.70.40.7-0.70.70.8-0.40.70.90.80.30.70.70.70.7-1.3
Locomotion velocity, session 10.90.92.2-0.10.1-0.10.3-0.3-0.6-0.7-0.9-0.70.5-0.9-1.11.0-1.3-1.3-1.1-1.3-1.5-1.5-1.5-1.50.2
Locomotion distance, session 12.73.55.51.4-2.0-2.22.3-2.3-2.3-2.4-1.7-2.32.3-2.2-2.2-0.3-1.9-2.0-2.00.1-1.4-1.4-1.4-1.41.3
Locomotion velocity, session 20.20.21.1-0.4-0.4-0.50.5-0.5-0.4-0.5-0.4-0.80.5-0.3-0.4-0.3-0.0-0.4-0.10.2-0.00.00.00.01.1
Locomotion distance, session 20.70.92.00.5-1.2-1.31.3-1.3-1.2-1.3-1.0-1.41.4-1.0-1.0-0.7-0.5-0.9-0.60.6-0.3-0.2-0.2-0.21.1
Locomotion velocity, session 32.52.86.00.9-0.3-0.50.8-0.8-1.3-1.4-1.2-1.01.1-1.8-1.91.4-2.3-2.1-2.2-1.9-2.5-2.4-2.4-2.4-0.6
Locomotion distance, session 30.60.62.41.6-0.5-0.30.4-0.4-0.7-0.6-0.7-0.20.2-0.9-0.80.1-1.1-0.7-1.1-0.6-1.1-1.0-1.0-1.0-1.1
Stereotopy head waving bouts, day 30.70.82.2-1.51.41.3-1.21.21.11.01.11.0-1.00.90.71.30.50.40.4-0.80.00.00.00.00.1
Stereotopy head waving duration, day 31.51.85.9-2.32.21.8-1.61.61.31.11.01.1-1.00.80.42.4-0.1-0.20.0-2.1-0.8-0.9-0.9-0.9-0.3
Locomotion velocity, session 70.30.30.90.60.10.4-0.50.50.40.6-0.00.6-0.60.50.7-0.60.50.80.70.30.60.60.60.6-0.9
Locomotion distance, session 71.11.43.91.2-0.40.2-0.50.40.50.9-0.00.9-0.80.91.3-2.01.31.71.61.51.61.61.61.6-1.4
Stereotopy head waving bouts, day 70.00.00.3-0.00.20.2-0.10.20.10.10.50.1-0.20.1-0.00.60.0-0.1-0.3-0.3-0.2-0.0-0.0-0.00.0
Stereotopy head waving duration, day 70.60.72.5-0.10.30.10.1-0.1-0.3-0.40.3-0.20.2-0.5-0.81.6-0.9-1.1-1.3-1.3-1.3-1.1-1.1-1.10.2
Locomotion velocity, session 80.10.10.4-0.60.20.1-0.20.20.30.30.60.2-0.10.50.4-0.20.50.40.40.30.50.50.50.5-0.2
Locomotion distance, session 80.10.10.80.7-0.4-0.40.3-0.3-0.4-0.3-0.4-0.30.4-0.4-0.3-0.4-0.3-0.2-0.30.0-0.2-0.1-0.1-0.1-0.9
Degree of sensitization distance3.03.06.9-0.60.20.5-0.90.81.21.51.11.1-1.11.82.0-1.82.42.32.42.12.62.52.52.5-0.1
Degree of sensitization stereotypy0.20.20.60.7-0.4-0.40.5-0.5-0.6-0.5-0.2-0.40.4-0.5-0.60.3-0.5-0.6-0.8-0.2-0.6-0.4-0.4-0.40.1
Conditioned locomotion1.21.43.20.9-0.00.5-0.80.80.91.21.21.2-1.11.21.5-1.21.21.81.11.21.51.51.51.5-1.4
Cocaine response after cond. corrected1.21.44.01.8-2.0-1.81.6-1.6-1.4-1.3-0.7-1.31.3-1.0-0.8-1.6-0.3-0.3-0.61.50.30.30.30.30.5
Cocaine response after cond. not corrected1.82.16.52.5-2.5-2.11.9-1.9-1.7-1.4-0.3-1.41.4-1.1-0.7-2.1-0.3-0.0-0.82.00.60.60.60.60.3
Cocaine response before conditioning0.40.51.31.0-0.5-0.1-0.10.10.20.41.20.5-0.50.40.7-0.80.51.00.00.90.80.80.80.8-0.8
Saline control response0.91.22.7-1.31.61.6-1.51.51.51.41.21.4-1.31.21.11.20.70.70.8-0.80.30.20.20.2-0.5
Bone: connectivity density0.71.08.4-2.91.71.1-0.80.80.80.40.00.2-0.10.40.01.60.1-0.60.4-1.4-0.6-0.7-0.7-0.71.1
Bone: cortical apparent density0.40.62.41.6-1.3-1.00.8-0.8-0.7-0.5-0.4-0.40.5-0.4-0.1-1.3-0.00.4-0.01.30.60.40.40.40.3
Bone: cortical area0.40.72.41.5-1.1-1.01.0-1.0-1.1-0.9-0.7-0.80.8-1.0-0.8-0.6-0.8-0.5-0.80.3-0.4-0.5-0.5-0.5-0.1
Bone: cortical porosity0.60.61.0-0.70.70.7-0.80.80.80.90.80.8-0.81.01.0-0.20.90.90.90.20.70.70.70.7-0.5
Bone: cortical porosity0.20.20.4-0.20.20.3-0.40.30.40.50.40.3-0.40.50.6-0.40.50.60.50.40.50.50.50.5-0.3
Bone: cortical thickness0.30.43.92.0-1.0-0.70.6-0.6-0.7-0.4-0.2-0.20.2-0.6-0.3-0.7-0.60.1-0.70.5-0.1-0.2-0.2-0.2-0.6
Bone: cortical thickness0.40.54.82.2-1.0-0.60.5-0.5-0.6-0.4-0.0-0.10.1-0.6-0.2-0.6-0.70.2-0.80.4-0.2-0.3-0.3-0.3-0.8
Bone: cortical tissue density0.50.62.41.5-1.4-1.10.9-0.9-0.7-0.5-0.4-0.50.5-0.5-0.1-1.3-0.00.4-0.01.30.60.50.50.50.4
Condit. Reinf. active minus inactive responses1.92.17.02.6-2.1-1.81.8-1.8-1.8-1.6-1.9-1.41.3-1.7-1.4-1.4-1.2-0.9-1.00.8-0.6-0.6-0.6-0.60.6
Condit. Reinf. active-inactive response ratio1.81.94.62.1-2.1-1.91.8-1.8-1.7-1.5-1.9-1.51.4-1.4-1.0-1.8-0.6-0.5-0.41.40.10.10.10.11.1
Condit. Reinf. active responses1.31.66.02.5-2.0-1.71.6-1.6-1.5-1.3-1.5-1.21.1-1.3-1.0-1.5-0.7-0.5-0.71.2-0.1-0.1-0.1-0.10.5
Condit. Reinf. inactive responses0.10.10.30.0-0.1-0.10.1-0.10.10.10.30.10.00.20.2-0.40.40.20.30.60.50.50.50.50.1
Incentive salience index mean1.72.15.62.4-2.1-1.91.8-1.8-1.8-1.7-1.9-1.51.4-1.6-1.4-1.3-1.1-1.0-0.90.9-0.5-0.5-0.5-0.50.9
Condit. Reinf. lever presses0.40.61.50.5-0.9-1.01.1-1.1-0.8-1.0-1.0-1.00.9-0.8-0.9-0.4-0.4-0.8-0.40.5-0.3-0.2-0.2-0.21.2
Condit. Reinf. active minus inactive responses0.91.22.50.60.20.7-0.90.91.01.21.21.3-1.11.21.4-0.71.11.60.90.91.21.21.21.2-1.1
Condit. Reinf. active-inactive response ratio1.01.23.61.8-1.9-1.61.4-1.5-1.3-1.1-0.1-1.11.1-0.8-0.6-1.3-0.2-0.1-0.71.50.50.50.50.50.5
Condit. Reinf. active responses4.15.610.3-0.72.12.6-2.82.82.93.02.83.2-3.02.82.90.22.12.81.90.11.71.71.71.7-2.5
Condit. Reinf. inactive responses8.010.418.7-2.53.94.2-4.34.34.24.13.24.3-4.23.73.61.52.33.02.6-1.41.31.31.31.3-3.1
Condit. Reinf. lever presses1.01.33.6-0.11.31.6-1.61.61.41.51.11.7-1.61.11.20.70.41.10.5-0.80.10.10.10.1-1.9
Condit. Reinf. lever reinforcers received4.66.411.8-0.82.32.9-3.13.13.13.23.03.4-3.33.03.10.32.23.02.1-0.01.71.71.71.7-2.7
Conditioned reinforcement - actives0.20.31.10.60.40.6-0.60.60.40.40.50.7-0.90.10.30.5-0.40.2-0.3-0.6-0.5-0.5-0.5-0.5-1.0
Conditioned reinforcement - inactives0.91.47.02.6-1.8-1.51.4-1.4-1.4-1.2-0.9-0.90.7-1.3-1.0-1.0-1.1-0.4-1.20.7-0.5-0.5-0.5-0.5-0.2
Conditioned locomotion0.40.51.2-1.01.11.0-0.90.90.90.71.10.8-1.00.70.51.00.30.20.1-0.7-0.1-0.1-0.1-0.1-0.3
Patch foraging indifference point 0 sec0.20.41.7-0.80.40.4-0.50.50.40.6-0.60.3-0.10.50.7-0.70.80.71.30.30.70.70.70.7-0.1
Patch foraging indifference point AUC0.81.21.90.4-0.7-1.01.1-1.1-1.2-1.3-1.1-1.31.4-1.3-1.30.3-1.2-1.4-1.2-0.3-1.0-1.0-1.0-1.01.0
Delay disc. indifference point, 0s delay1.41.53.4-0.3-0.1-0.50.7-0.7-0.7-1.1-0.6-0.80.8-1.1-1.51.2-1.6-1.8-1.5-1.2-1.8-1.8-1.8-1.80.3
Delay disc. indifference point, 16s delay0.50.63.31.0-1.0-0.90.9-0.9-0.8-0.7-0.6-0.81.1-0.8-0.4-0.8-0.1-0.2-0.20.70.20.20.20.21.8
Delay disc. indifference point, 2s delay1.11.22.10.5-1.2-1.31.4-1.4-1.2-1.4-1.3-1.41.3-1.2-1.4-0.5-0.9-1.3-0.80.3-0.7-0.7-0.7-0.71.3
Delay disc. indifference point, 24s delay0.80.82.9-1.71.51.3-1.31.31.21.10.80.9-0.50.70.81.10.50.40.6-1.0-0.0-0.0-0.0-0.0-0.1
Delay disc. indifference point, 4s delay1.92.04.11.3-2.0-2.02.0-2.0-1.7-1.7-1.6-1.82.0-1.5-1.3-1.6-0.5-0.9-0.51.30.10.10.10.11.6
Delay disc. indifference point, 8s delay0.20.32.40.5-0.4-0.30.3-0.3-0.1-0.00.5-0.10.10.00.2-0.50.40.30.00.80.70.70.70.71.6
Indifference point function ln k1.22.13.9-1.21.92.0-2.02.01.81.81.71.9-2.01.71.50.81.01.20.9-0.90.40.50.50.5-1.7
Indifference point function log k1.22.13.9-1.21.92.0-2.02.01.81.81.71.9-2.01.71.50.81.01.20.9-0.90.40.50.50.5-1.7
Patch foraging total patch changes 0 sec0.20.31.6-0.80.40.4-0.50.50.40.6-0.70.4-0.20.50.6-0.70.70.61.30.20.60.60.60.6-0.0
Patch foraging total patch changes 12 sec0.40.61.8-0.1-0.7-0.90.9-0.9-1.0-0.9-0.9-1.11.4-0.8-0.7-0.3-0.4-0.7-0.30.3-0.2-0.3-0.3-0.31.2
Patch foraging total patch changes 18 sec0.71.04.7-0.4-0.8-1.11.1-1.1-1.1-1.1-2.2-1.41.6-1.1-1.0-0.8-0.4-0.90.20.4-0.2-0.3-0.3-0.31.4
Patch foraging total patch changes 24 sec0.81.34.10.2-1.4-1.31.1-1.1-0.9-0.7-1.3-1.01.2-0.4-0.1-2.00.70.30.91.91.11.11.11.11.8
Patch foraging total patch changes 6 sec0.30.52.9-0.3-0.4-0.70.7-0.7-0.8-0.7-1.7-0.91.1-0.7-0.7-0.5-0.3-0.70.20.1-0.3-0.3-0.3-0.30.9
Patch foraging time to switch 0 sec0.20.41.20.1-0.5-0.30.2-0.20.10.20.70.0-0.00.50.5-0.80.90.70.51.11.11.11.11.10.1
Patch foraging water rate 0 sec0.30.72.91.0-1.0-1.01.0-1.0-0.9-0.9-1.7-0.80.8-0.9-0.7-1.0-0.5-0.5-0.00.5-0.2-0.2-0.2-0.20.8
Patch foraging water rate 12 sec0.30.71.90.4-0.30.0-0.20.20.40.6-0.50.4-0.50.50.9-1.31.01.21.41.11.21.21.21.20.7
Patch foraging water rate 18 sec1.21.96.01.2-2.0-1.91.8-1.8-1.7-1.6-2.0-1.61.5-1.3-1.2-1.2-0.6-0.7-0.41.1-0.1-0.1-0.1-0.12.5
Patch foraging water rate 24 sec0.20.31.20.5-0.6-0.40.3-0.3-0.00.00.1-0.0-0.00.20.3-0.90.60.50.51.10.90.80.80.80.8
Patch foraging water rate 6 sec1.21.74.00.2-0.30.1-0.40.40.60.9-0.10.7-0.81.01.4-2.01.61.81.91.71.91.91.91.90.5
Seeking ratio, delayed vs. immediate footshock0.81.03.30.31.11.3-1.21.21.31.21.21.5-1.81.20.90.80.40.70.5-0.50.20.20.20.2-0.9
Distance traveled before self-admin0.10.20.4-0.3-0.5-0.50.5-0.5-0.5-0.30.3-0.60.6-0.0-0.1-0.30.20.0-0.30.50.30.30.30.30.3
Distance traveled after self-admin0.10.10.30.1-0.4-0.40.3-0.3-0.3-0.3-0.5-0.30.5-0.3-0.1-0.50.1-0.10.30.40.20.20.20.2-0.2
Extensor digitorum longus weight0.31.34.10.5-1.5-1.31.1-1.2-0.8-0.7-0.8-1.00.8-0.2-0.1-2.00.80.30.82.01.31.31.31.31.5
Bone: elastic displacement0.30.41.41.1-0.00.4-0.50.50.50.60.80.8-0.80.40.7-0.20.10.90.00.20.40.30.30.3-1.2
Bone: elastic work0.10.10.50.7-0.3-0.20.1-0.1-0.3-0.2-0.1-0.10.0-0.3-0.20.0-0.5-0.1-0.5-0.2-0.4-0.4-0.4-0.4-0.4
Bone: endosteal estimation0.10.21.2-1.10.70.4-0.30.30.20.0-0.1-0.00.10.0-0.20.8-0.2-0.5-0.0-0.8-0.5-0.5-0.5-0.50.3
Bone: endosteal perimeter0.10.20.4-0.6-0.0-0.30.4-0.4-0.4-0.5-0.6-0.60.7-0.4-0.50.1-0.2-0.6-0.1-0.2-0.3-0.2-0.2-0.20.6
Epididymis fat weight0.82.85.92.2-2.4-2.32.3-2.3-2.2-2.0-1.9-2.02.1-1.8-1.5-1.7-0.8-1.0-0.81.4-0.1-0.1-0.1-0.10.7
Delta time in closed arm before/after self-admin0.50.53.2-0.6-0.7-0.80.8-0.8-0.7-0.8-0.7-0.90.8-0.4-0.6-0.6-0.1-0.50.00.40.0-0.0-0.0-0.01.8
Delta time in open arm before/after self-admin0.50.51.81.2-0.9-0.80.8-0.8-0.8-0.70.4-0.60.7-0.7-0.60.1-0.6-0.5-1.30.3-0.3-0.3-0.3-0.30.3
Diff in mean of infusions in LGA sessions0.20.20.8-0.90.70.5-0.40.40.40.1-0.60.2-0.4-0.0-0.10.7-0.3-0.50.1-0.9-0.6-0.6-0.6-0.6-0.1
Delay discount exponential model param0.80.93.3-0.91.31.2-1.11.10.90.80.61.0-1.20.70.41.3-0.20.1-0.0-1.2-0.6-0.6-0.6-0.6-1.8
Extinction: sum of active levers before priming1.11.32.30.9-1.3-1.41.5-1.5-1.5-1.4-1.3-1.51.1-1.2-1.3-0.6-0.9-1.1-1.00.4-0.6-0.6-0.6-0.61.1
Active lever presses in extinction session 60.70.73.31.1-1.1-1.01.0-1.0-0.9-0.9-1.8-0.90.8-0.8-0.7-1.2-0.5-0.50.10.6-0.2-0.2-0.2-0.20.6
Bone: final force1.22.03.70.9-0.6-0.81.0-1.0-1.4-1.4-1.3-1.21.1-1.7-1.70.8-1.9-1.7-1.8-1.1-1.8-1.9-1.9-1.90.2
Bone: final moment1.11.73.30.8-0.5-0.70.9-0.9-1.2-1.2-1.2-1.00.9-1.5-1.50.8-1.8-1.6-1.7-1.2-1.8-1.8-1.8-1.80.2
Food consumed during 24 hour testing period1.62.24.30.9-0.7-0.91.1-1.1-1.4-1.5-1.1-1.31.3-1.7-1.81.0-2.0-1.9-2.1-1.2-1.9-1.9-1.9-1.90.4
Glucose0.10.10.80.10.40.5-0.50.50.40.40.50.5-0.50.30.30.30.10.2-0.0-0.4-0.1-0.1-0.1-0.1-0.9
Heart weight1.01.53.51.9-1.9-1.71.6-1.6-1.6-1.4-1.3-1.51.5-1.3-1.0-1.3-0.6-0.6-0.61.20.0-0.0-0.0-0.00.8
Delay discount hyperbolic model param0.80.93.4-0.91.31.2-1.21.21.00.90.71.0-1.20.80.51.3-0.10.20.1-1.2-0.6-0.6-0.6-0.6-1.8
Intermittent access intake day 1-15 change0.30.71.4-0.90.60.6-0.60.60.70.80.90.6-0.61.00.9-0.11.20.90.80.41.11.11.11.1-0.2
Intermittent access intake escalation0.20.41.0-0.90.40.4-0.40.40.50.60.70.3-0.30.80.7-0.11.00.60.70.40.90.90.90.90.0
Intermittent access intake escalation 20.80.91.8-0.0-1.2-1.31.3-1.3-1.2-1.0-1.0-1.31.3-0.7-0.7-1.10.2-0.5-0.11.10.50.50.50.51.1
Intermitt. access day 1 inactive lever presses0.10.61.50.70.10.1-0.00.0-0.0-0.30.10.1-0.3-0.5-0.50.8-1.2-0.6-1.0-0.9-1.2-1.2-1.2-1.2-0.7
Intermitt. access day 15 inactive lever presses1.73.59.71.2-0.7-0.1-0.20.20.31.10.20.6-0.71.31.8-2.62.42.41.92.63.13.13.13.10.0
Intermitt. access escalation Index0.40.61.2-0.1-0.7-0.90.9-0.9-0.8-1.0-1.0-1.01.1-0.9-0.9-0.2-0.5-0.9-0.40.1-0.5-0.5-0.5-0.51.1
Intermittent access day 1 total infusions0.10.21.41.2-0.00.3-0.30.30.20.40.90.6-0.80.20.30.2-0.20.5-0.4-0.1-0.1-0.1-0.1-0.1-0.7
Intermittent access day 15 total infusions0.20.30.90.6-0.00.2-0.30.30.30.50.90.5-0.70.50.6-0.10.50.70.00.40.60.60.60.6-0.5
Intermittent access terminal intake (last 3 days)0.10.20.80.50.20.3-0.40.40.40.40.90.5-0.60.40.40.20.20.5-0.10.10.30.30.30.3-0.6
Intermittent access total infusions0.10.11.11.1-0.3-0.10.0-0.0-0.10.00.60.2-0.3-0.00.10.0-0.20.2-0.50.1-0.1-0.1-0.1-0.1-0.5
Intermittent access day 1 locomotion0.30.42.21.5-0.10.1-0.10.10.0-0.00.90.4-0.6-0.3-0.20.7-0.8-0.1-1.1-0.5-0.8-0.8-0.8-0.8-0.9
Intermittent access day 15 total locomotion0.50.94.50.80.71.0-1.01.01.00.92.11.3-1.50.70.71.1-0.10.6-0.6-0.6-0.2-0.2-0.2-0.2-1.4
Intermittent access total locomotion0.30.41.50.80.40.6-0.50.50.50.41.20.8-0.90.30.20.8-0.40.2-0.6-0.6-0.5-0.5-0.5-0.5-1.0
Intermittent access standard deviation0.30.63.11.7-0.9-0.70.7-0.7-0.8-0.7-0.1-0.40.3-0.8-0.7-0.0-1.0-0.5-1.2-0.0-0.8-0.8-0.8-0.8-0.6
Left kidney weight1.15.119.64.4-3.5-3.02.9-2.9-2.8-2.5-2.0-2.12.1-2.6-2.0-2.0-1.8-1.1-1.91.6-0.6-0.7-0.7-0.70.7
Right kidney weight2.410.932.45.7-4.6-4.14.1-4.1-4.1-3.9-3.2-3.13.2-4.0-3.4-1.8-3.3-2.4-3.41.3-1.8-1.9-1.9-1.90.8
Cocaine induced anxiety0.30.51.10.3-0.8-0.90.9-1.0-0.8-0.9-1.0-0.91.0-0.7-0.7-0.7-0.3-0.6-0.20.5-0.1-0.1-0.1-0.10.4
Post-drug Anxiety0.60.61.30.3-1.1-1.11.1-1.1-0.9-0.8-1.1-1.01.1-0.6-0.5-1.10.1-0.30.11.00.40.40.40.40.9
Baseline Anxiety0.00.00.1-0.00.10.2-0.20.20.10.10.20.2-0.10.00.10.3-0.10.1-0.1-0.3-0.2-0.2-0.2-0.2-0.1
Tail length1.03.99.53.1-2.8-2.62.5-2.5-2.5-2.3-2.1-2.22.2-2.3-1.9-1.4-1.6-1.3-1.71.0-0.8-0.8-0.8-0.81.0
Length with tail1.56.314.83.8-3.0-2.82.9-2.9-3.0-3.0-2.6-2.52.5-3.2-2.8-0.8-2.7-2.3-2.70.3-1.9-1.9-1.9-1.90.7
Length without tail2.37.613.23.6-3.3-3.23.3-3.3-3.4-3.3-3.0-2.93.1-3.5-3.1-1.2-2.8-2.5-2.70.5-1.9-1.9-1.9-1.90.9
Times rat made contact with spout0.20.31.20.30.10.1-0.00.0-0.2-0.2-1.1-0.00.0-0.5-0.40.3-0.7-0.5-0.1-0.8-0.8-0.8-0.8-0.8-0.1
Lifetime Intake0.10.20.90.9-0.00.1-0.20.20.00.10.70.3-0.4-0.10.00.4-0.40.1-0.6-0.3-0.4-0.4-0.4-0.4-0.7
Liver weight, left0.20.31.71.3-1.0-0.70.6-0.6-0.5-0.4-0.2-0.30.2-0.3-0.2-0.9-0.10.1-0.20.90.40.30.30.30.3
Liver weight, right0.50.81.81.3-0.5-0.0-0.20.20.30.60.70.7-0.80.71.0-1.20.81.40.71.31.21.21.21.2-0.7
Locomotor activity0.40.51.50.30.60.9-1.01.00.91.00.71.1-1.20.81.00.20.51.00.5-0.10.40.40.40.4-0.2
Locomotor testing distance0.50.92.3-0.31.31.4-1.41.41.21.30.91.4-1.50.91.00.90.30.80.5-0.70.10.10.10.1-0.2
Locomotor testing rearing1.63.16.4-1.22.42.5-2.52.52.32.21.92.4-2.51.81.81.70.81.40.8-1.40.20.20.20.2-1.5
Locomotion in novel chamber1.21.52.51.6-1.3-1.31.4-1.4-1.3-1.4-0.7-1.31.1-1.3-1.4-0.2-1.4-1.2-1.50.1-1.1-1.1-1.1-1.11.1
Locomotion in novel chamber post-restriction1.11.74.11.2-0.6-0.70.8-0.8-0.8-1.2-1.0-0.70.8-1.6-1.40.5-2.0-1.5-1.5-0.9-2.0-2.0-2.0-2.00.4
Fecal boli incidents, locomotor time 11.11.73.90.7-1.6-1.71.7-1.7-1.6-1.7-0.7-1.71.4-1.3-1.5-0.4-0.9-1.3-1.30.5-0.6-0.6-0.6-0.62.0
Change in fecal boli incidents, locomotor task3.03.05.1-0.61.61.9-2.01.92.12.22.32.0-1.82.12.20.31.92.01.50.31.61.61.61.6-0.3
Time >=10cm from walls, locomotor time 10.20.20.6-0.0-0.4-0.50.5-0.5-0.5-0.4-0.6-0.60.8-0.3-0.3-0.50.1-0.30.20.40.20.20.20.20.7
Bouts of movement, locomotor time 10.10.10.80.4-0.20.0-0.10.10.10.20.20.1-0.00.20.4-0.40.30.60.10.30.40.40.40.40.9
Total resting periods, locomotor time 10.10.10.40.6-0.3-0.1-0.00.0-0.00.20.10.1-0.10.10.3-0.50.30.60.20.40.50.50.50.50.6
Rest time, locomotor task time 10.30.41.00.5-0.4-0.10.0-0.0-0.10.30.30.1-0.10.40.6-0.80.70.80.50.91.01.01.01.00.3
Distance moved, locomotor task time 10.10.10.8-0.90.40.2-0.10.10.2-0.10.2-0.1-0.00.0-0.20.6-0.2-0.4-0.2-0.5-0.4-0.4-0.4-0.40.1
Vertical activity count, locomotor time 10.81.95.3-0.60.60.20.0-0.0-0.0-0.6-0.3-0.20.1-0.8-1.21.9-1.8-1.7-1.5-1.9-2.3-2.3-2.3-2.3-0.6
Time >=10cm from walls, locomotor time 20.00.00.2-0.10.10.00.0-0.00.20.0-0.30.10.00.10.0-0.20.2-0.10.40.10.20.20.20.2-0.4
Bouts of movement, locomotor time 20.40.61.5-1.11.10.9-0.80.80.90.4-0.70.8-0.70.20.01.1-0.3-0.30.4-1.2-0.8-0.8-0.8-0.8-0.8
Total resting periods, locomotor time 20.30.61.6-0.40.80.6-0.50.50.50.1-0.80.5-0.6-0.1-0.31.1-0.7-0.6-0.1-1.3-1.1-1.1-1.1-1.1-0.6
Rest time, locomotor task time 20.91.12.91.5-1.6-1.41.3-1.3-1.2-0.9-0.6-1.20.9-0.5-0.4-1.70.30.1-0.11.60.80.80.80.81.0
Distance moved, locomotor task time 21.31.63.6-1.11.71.6-1.51.51.51.11.31.5-1.60.80.61.9-0.20.1-0.1-1.7-0.8-0.8-0.8-0.8-1.5
Vertical activity count, locomotor time 21.01.33.8-1.31.20.9-0.80.80.70.20.10.7-0.2-0.1-0.41.9-1.0-0.8-0.6-1.9-1.6-1.6-1.6-1.6-1.6
Light reinforcement 10.61.54.7-0.81.10.7-0.50.50.2-0.1-0.50.1-0.1-0.5-0.82.1-1.4-1.3-1.1-2.2-1.9-1.9-1.9-1.90.2
Light reinforcement 21.01.53.9-0.20.40.00.3-0.2-0.5-0.8-0.8-0.60.4-1.0-1.31.6-1.7-1.6-1.4-1.8-2.0-2.0-2.0-2.00.3
Bone: marrow area0.10.21.2-1.10.60.3-0.10.10.0-0.1-0.3-0.20.2-0.2-0.40.8-0.3-0.7-0.1-0.8-0.6-0.6-0.6-0.60.5
Bone: maximum diameter0.30.61.20.5-1.0-1.11.1-1.1-1.0-0.9-1.0-1.11.0-0.7-0.6-1.0-0.2-0.4-0.10.80.10.10.10.10.7
Bone: maximum force1.11.93.11.7-1.4-1.41.4-1.4-1.7-1.6-1.4-1.41.3-1.8-1.6-0.2-1.7-1.4-1.7-0.3-1.4-1.4-1.4-1.40.2
Bone: maximum moment0.91.62.61.6-1.2-1.21.3-1.3-1.5-1.4-1.3-1.21.1-1.6-1.5-0.1-1.6-1.3-1.6-0.3-1.3-1.3-1.3-1.30.2
Mean time between licks in bursts0.51.23.70.01.31.5-1.41.41.21.21.41.5-1.50.80.81.2-0.00.6-0.1-1.2-0.4-0.4-0.4-0.4-1.9
Mean num. licks in bursts0.50.81.8-0.40.40.6-0.80.80.91.00.60.9-0.91.01.2-0.51.11.21.30.61.11.11.11.1-0.1
Cd content in liver0.30.31.61.2-0.3-0.10.1-0.1-0.3-0.20.00.1-0.1-0.4-0.30.2-0.8-0.2-0.8-0.4-0.6-0.6-0.6-0.6-1.0
Co content in liver0.60.71.71.3-0.00.1-0.00.1-0.2-0.20.10.2-0.2-0.6-0.50.8-1.2-0.5-1.3-1.0-1.2-1.2-1.2-1.2-1.3
Cu content in liver2.83.38.83.0-1.7-1.61.7-1.7-1.9-1.9-2.0-1.41.3-2.3-2.0-0.0-2.4-1.8-2.1-0.6-2.0-2.0-2.0-2.0-0.3
Fe content in liver1.31.62.6-1.01.31.5-1.51.51.61.61.01.6-1.61.51.50.11.21.31.6-0.10.90.90.90.9-0.7
K content in liver0.20.20.40.4-0.2-0.20.3-0.2-0.3-0.4-0.2-0.30.3-0.5-0.50.4-0.6-0.5-0.6-0.4-0.5-0.5-0.5-0.5-0.1
Mg content in liver0.10.10.40.60.00.2-0.20.20.20.2-0.10.4-0.4-0.00.1-0.0-0.20.20.1-0.2-0.1-0.1-0.1-0.1-0.5
Mn content in liver1.21.42.9-1.11.71.7-1.61.61.51.41.21.6-1.51.21.01.10.50.70.6-1.1-0.0-0.1-0.1-0.1-1.3
Na content in liver1.01.13.8-0.01.10.9-0.70.70.50.20.10.6-0.7-0.2-0.41.8-1.1-0.8-0.9-1.9-1.5-1.5-1.5-1.5-0.7
Rb content in liver0.40.52.40.3-0.7-0.60.5-0.6-0.4-0.3-1.6-0.50.5-0.2-0.1-1.50.30.11.10.90.50.50.50.50.5
Se content in liver1.31.63.4-0.50.81.1-1.21.21.31.41.81.4-1.51.61.6-0.01.41.61.00.51.31.31.31.3-0.9
Sr content in liver0.70.62.4-1.31.21.0-0.90.90.80.61.10.6-0.60.50.31.5-0.0-0.1-0.3-1.1-0.5-0.5-0.5-0.5-0.4
Zn content in liver0.30.41.10.9-0.9-0.90.8-0.8-0.7-0.7-1.1-0.70.6-0.6-0.5-0.8-0.2-0.20.10.50.10.10.10.10.5
Bone: minimum diameter0.00.10.20.2-0.3-0.30.3-0.3-0.2-0.2-0.2-0.30.3-0.1-0.1-0.40.1-0.00.10.40.20.20.20.20.2
Time in familiar zone, hab. session 10.90.83.4-0.70.80.4-0.20.20.0-0.20.5-0.20.1-0.4-0.71.8-1.0-1.1-1.2-1.6-1.3-1.3-1.3-1.30.2
Time in novel zone, hab. session 10.30.31.60.5-0.7-0.60.5-0.5-0.4-0.2-0.9-0.30.3-0.20.0-1.30.20.30.50.90.50.40.40.40.1
Total zone transitions, hab. session 10.00.00.1-0.10.0-0.10.1-0.10.0-0.10.3-0.10.1-0.1-0.10.1-0.1-0.2-0.20.1-0.1-0.1-0.1-0.10.1
Total locomotion distance, hab. session 10.60.94.12.0-1.6-1.31.2-1.2-1.1-0.9-0.7-0.80.8-0.9-0.6-1.3-0.5-0.1-0.51.10.10.10.10.10.1
Locomotion velocity, hab. session 10.30.42.01.4-1.1-0.90.8-0.8-0.7-0.6-0.5-0.40.5-0.6-0.3-0.9-0.3-0.0-0.30.80.20.10.10.10.0
Time in familiar zone, hab. session 20.60.61.4-1.10.80.8-0.80.80.90.91.20.7-0.81.00.90.30.90.80.70.10.70.70.70.70.1
Time in novel zone, hab. session 21.31.32.10.6-0.6-0.81.0-1.0-1.2-1.2-1.5-1.11.1-1.4-1.40.3-1.4-1.4-1.2-0.8-1.3-1.4-1.4-1.40.2
Total zone transitions, hab. session 20.10.10.30.00.30.3-0.20.30.30.10.00.3-0.3-0.0-0.00.5-0.4-0.2-0.2-0.5-0.4-0.5-0.5-0.5-0.1
Total locomotion distance, hab. session 20.20.22.01.4-0.8-0.60.5-0.5-0.4-0.3-0.0-0.10.2-0.4-0.1-0.5-0.30.1-0.40.60.20.10.10.1-0.1
Locomotion velocity, hab. session 20.20.22.41.5-0.8-0.50.4-0.4-0.2-0.20.10.0-0.0-0.3-0.0-0.5-0.20.2-0.30.70.20.20.20.2-0.2
Novel to familiar place preference ratio0.20.21.20.4-0.4-0.30.2-0.2-0.1-0.1-1.1-0.00.1-0.10.1-1.10.20.30.70.60.30.40.40.4-0.1
Novelty place preference0.10.21.10.2-0.3-0.20.1-0.1-0.00.0-1.00.10.0-0.00.1-1.00.20.30.70.50.30.30.30.3-0.1
Time in novel zone, NPP test0.20.21.20.2-0.3-0.10.0-0.00.10.1-0.80.1-0.10.10.3-1.10.40.50.80.60.50.50.50.5-0.2
Total zone transitions, NPP test0.00.00.20.5-0.1-0.10.1-0.1-0.0-0.00.30.0-0.1-0.1-0.0-0.1-0.20.0-0.30.1-0.0-0.1-0.1-0.1-0.1
Total locomotion distance, NPP test0.10.22.41.5-0.6-0.30.3-0.3-0.3-0.2-0.1-0.0-0.1-0.3-0.1-0.5-0.40.1-0.40.3-0.1-0.1-0.1-0.1-0.7
Locomotion velocity, NPP test0.10.22.21.5-0.6-0.40.3-0.3-0.3-0.2-0.1-0.0-0.0-0.3-0.1-0.6-0.30.1-0.30.40.10.00.00.0-0.5
Intraocular pressure1.92.74.8-2.21.31.3-1.41.41.71.72.01.2-1.32.11.9-0.22.21.71.90.71.91.91.91.9-0.1
Delta distance traveled before/after self-admin0.30.31.20.30.70.8-0.80.80.70.7-0.00.9-0.60.20.50.40.00.40.4-0.6-0.1-0.2-0.2-0.2-1.1
Delta ambulatory time before/after self-admin0.30.41.40.40.70.9-0.80.90.80.70.11.0-0.70.30.50.40.10.50.5-0.5-0.1-0.1-0.1-0.1-1.2
Parametrial fat weight0.30.64.61.5-0.10.3-0.50.50.60.60.80.9-0.60.40.8-0.40.41.00.20.50.60.70.70.7-2.1
Pavlov. Cond. lever latency1.01.32.4-1.11.51.5-1.51.51.31.41.41.4-1.41.21.11.00.60.90.6-0.90.20.10.10.1-1.3
Pavlov. Cond. magazine entry latency0.30.40.70.8-0.3-0.30.4-0.4-0.4-0.6-0.8-0.40.3-0.7-0.70.3-0.9-0.7-0.7-0.4-0.8-0.8-0.8-0.80.1
Pavlov. Cond. change in total contacts2.93.15.11.9-1.9-2.02.2-2.2-2.0-2.2-2.3-1.92.0-2.2-2.1-0.5-1.7-1.9-1.50.3-1.3-1.1-1.1-1.11.6
Pavlov. Cond. index score0.81.01.91.4-1.3-1.21.3-1.3-1.2-1.2-1.3-1.01.1-1.2-1.1-0.5-0.9-0.9-0.80.3-0.6-0.5-0.5-0.50.7
Pavlov. Cond. latency score1.01.32.31.5-1.4-1.41.4-1.4-1.3-1.4-1.4-1.21.2-1.4-1.3-0.6-1.0-1.0-1.00.4-0.7-0.6-0.6-0.60.8
Pavlov. Cond. lever contacts1.01.12.21.3-1.5-1.41.4-1.4-1.2-1.3-1.4-1.21.2-1.2-1.0-1.0-0.6-0.8-0.50.9-0.3-0.2-0.2-0.21.2
Pavlov. Cond. magazine entry number0.30.30.8-0.70.30.3-0.40.40.40.60.90.3-0.40.70.7-0.10.80.70.50.40.70.70.70.70.0
Pavlov. Cond. intertrial magazine entries0.10.21.11.0-0.6-0.40.4-0.4-0.5-0.4-0.7-0.20.2-0.5-0.3-0.5-0.4-0.1-0.20.2-0.2-0.2-0.2-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.91.2-1.3-1.31.3-1.3-1.2-1.3-1.4-1.11.1-1.2-1.1-0.5-0.8-0.9-0.70.4-0.5-0.4-0.4-0.40.9
Pavlov. Cond. response bias0.30.41.30.6-0.7-0.70.8-0.8-0.7-0.8-1.1-0.70.7-0.8-0.8-0.3-0.6-0.7-0.40.1-0.5-0.4-0.4-0.40.5
Pavlov. Cond. lever latency1.31.75.0-0.6-1.3-1.41.1-1.2-0.7-0.6-0.5-1.21.10.10.1-1.91.30.41.22.21.71.71.71.72.0
Pavlov. Cond. magazine entry latency4.45.39.91.6-2.2-2.52.6-2.6-2.8-2.8-3.1-2.82.7-2.9-2.8-0.3-2.4-2.6-2.0-0.3-1.9-1.9-1.9-1.91.4
Pavlov. Cond. change in total contacts0.81.33.20.21.41.4-1.31.31.00.90.61.4-1.30.30.31.6-0.70.0-0.5-1.8-1.1-1.1-1.1-1.1-1.7
Pavlov. Cond. index score1.01.33.21.1-0.1-0.10.2-0.2-0.6-0.7-1.0-0.30.3-1.2-1.11.0-1.7-1.2-1.5-1.5-1.8-1.8-1.8-1.8-0.9
Pavlov. Cond. latency score1.72.35.01.3-0.4-0.50.7-0.7-1.1-1.2-1.4-0.80.8-1.7-1.61.2-2.2-1.7-1.9-1.7-2.2-2.2-2.2-2.2-0.6
Pavlov. Cond. lever contacts1.21.64.70.71.21.2-1.01.10.60.50.21.1-1.0-0.2-0.11.8-1.4-0.5-1.1-2.2-1.7-1.7-1.7-1.7-1.9
Pavlov. Cond. magazine entry number2.02.56.6-1.01.31.5-1.61.61.81.82.61.8-1.72.01.90.21.71.81.20.51.51.51.51.5-0.7
Pavlov. Cond. intertrial magazine entries2.43.66.1-0.91.61.9-2.12.12.22.32.52.3-2.22.42.40.11.92.31.70.41.71.71.71.7-1.3
Pavlov. Cond. lever-magazine prob. diff.1.21.63.71.2-0.2-0.20.4-0.4-0.8-0.9-1.2-0.50.5-1.4-1.31.0-1.9-1.4-1.6-1.5-1.9-1.9-1.9-1.9-0.7
Pavlov. Cond. response bias0.71.02.90.41.11.1-1.01.00.60.60.11.0-0.90.00.11.2-0.9-0.2-0.6-1.7-1.2-1.2-1.2-1.2-1.7
Time in closed arm before self-admin0.10.21.6-0.50.40.3-0.30.30.30.3-0.10.2-0.50.30.3-0.00.40.20.50.00.20.20.20.21.3
Time in closed arm after self-admin0.20.23.7-0.6-0.3-0.40.4-0.4-0.3-0.4-0.3-0.40.3-0.1-0.3-0.20.0-0.30.00.20.10.10.10.11.9
Time in open arm before self-admin1.01.02.0-1.41.41.3-1.31.31.41.20.41.2-1.31.21.10.40.80.81.3-0.40.50.50.50.5-0.4
Time in open arm after self-admin0.50.63.41.8-1.2-1.00.9-0.9-0.9-0.8-0.2-0.70.5-0.7-0.5-0.7-0.5-0.2-0.80.7-0.1-0.1-0.1-0.1-0.2
Bone: periosteal estimation0.10.30.60.1-0.2-0.40.5-0.4-0.5-0.6-0.6-0.60.6-0.7-0.70.3-0.7-0.8-0.6-0.4-0.7-0.7-0.7-0.70.3
Bone: periosteal perimeter0.10.10.3-0.1-0.0-0.10.2-0.2-0.3-0.3-0.4-0.30.2-0.4-0.50.2-0.4-0.5-0.4-0.4-0.5-0.5-0.5-0.5-0.0
Bone: post-yield work0.10.20.5-0.10.20.1-0.00.0-0.1-0.2-0.2-0.10.0-0.3-0.40.6-0.6-0.5-0.5-0.7-0.7-0.7-0.7-0.7-0.2
Progressive ratio test 1 active lever presses0.60.73.11.80.20.5-0.60.60.50.41.21.0-1.10.10.20.7-0.70.3-0.9-0.6-0.7-0.7-0.7-0.7-1.7
Progressive ratio test 1 breakpoint0.60.73.21.80.20.5-0.60.60.40.41.21.0-1.10.10.20.7-0.70.3-0.9-0.6-0.6-0.6-0.6-0.6-1.7
Progressive ratio test 1 inactive lever presses1.52.25.60.41.61.9-1.91.91.91.82.12.2-2.41.51.61.00.61.40.4-0.70.30.30.30.3-1.9
Progressive ratio test 2 active lever presses0.20.20.90.90.20.3-0.30.30.20.20.50.5-0.6-0.00.10.5-0.40.0-0.5-0.4-0.5-0.5-0.5-0.5-1.0
Progressive ratio test 2 breakpoint0.20.20.80.90.10.2-0.20.20.20.10.50.4-0.6-0.00.00.4-0.40.0-0.5-0.4-0.4-0.4-0.4-0.4-0.9
Progressive ratio test 2 inactive lever presses0.91.44.32.1-0.8-0.2-0.00.00.10.60.40.5-0.70.61.1-1.61.21.60.71.71.81.81.81.8-0.6
Incentive Sensitization - Responses0.00.00.1-0.20.30.2-0.20.20.20.10.10.2-0.20.10.00.2-0.0-0.10.0-0.2-0.1-0.1-0.1-0.1-0.2
Incentive Sensitization - Breakpoint0.00.00.1-0.20.20.2-0.20.20.20.20.00.2-0.20.20.20.00.20.10.2-0.00.10.10.10.1-0.2
Sum of active levers in priming session hrs 5-60.70.72.30.3-0.4-0.50.7-0.7-0.7-0.9-1.5-0.70.7-0.9-1.00.0-1.0-1.0-0.4-0.6-1.0-1.0-1.0-1.00.3
Progressive ratio0.61.05.8-2.41.71.3-1.11.11.10.70.70.7-0.60.90.31.50.3-0.30.5-1.2-0.4-0.4-0.4-0.4-0.3
Food seeking constrained by brief footshock0.40.51.4-0.90.70.5-0.40.40.20.00.50.1-0.1-0.2-0.31.2-0.8-0.6-0.7-1.2-1.1-1.1-1.1-1.10.1
Seeking ratio, punishment vs. effort0.40.61.91.4-1.1-1.00.8-0.8-1.0-0.8-0.4-0.80.7-1.0-0.6-0.5-0.8-0.3-1.00.3-0.4-0.4-0.4-0.40.5
Retroperitoneal fat weight1.66.718.74.3-3.5-3.23.2-3.2-3.1-3.1-2.7-2.62.9-3.1-2.7-1.5-2.4-2.1-2.51.0-1.4-1.3-1.3-1.3-0.3
Reaction time number correct0.71.44.6-1.71.91.5-1.21.21.00.6-0.20.8-0.80.3-0.02.0-0.6-0.7-0.0-2.1-1.3-1.3-1.3-1.30.0
Reaction time mean minus median0.40.91.70.8-1.1-1.21.2-1.2-1.2-1.2-0.1-1.31.3-1.1-1.10.1-0.7-0.9-1.20.3-0.5-0.5-0.5-0.50.9
Reaction time mean minus median AUC0.51.22.20.4-1.0-1.21.3-1.3-1.3-1.4-0.2-1.41.5-1.2-1.30.5-0.9-1.3-1.4-0.1-0.8-0.8-0.8-0.81.2
Reaction time num false alarms4.66.410.01.4-2.5-2.83.0-3.0-3.1-3.2-3.0-3.23.1-3.1-3.1-0.6-2.5-2.8-2.20.1-1.9-1.9-1.9-1.92.2
Reaction time num false alarms AUC3.96.110.01.3-2.6-2.93.0-3.0-3.1-3.1-3.1-3.23.1-2.9-2.9-0.9-2.2-2.7-2.00.3-1.7-1.7-1.7-1.72.2
Reaction time trials correct on left0.71.44.6-1.71.91.5-1.21.21.00.6-0.20.8-0.80.3-0.02.0-0.6-0.7-0.0-2.1-1.3-1.3-1.3-1.30.0
Reaction time trials on left0.71.34.5-1.61.81.4-1.11.10.90.5-0.30.7-0.70.2-0.11.9-0.7-0.8-0.1-2.1-1.3-1.3-1.3-1.30.0
Reaction time mean0.40.61.40.6-1.1-1.21.1-1.1-1.1-1.0-0.5-1.11.2-0.8-0.8-0.5-0.3-0.5-0.60.6-0.0-0.0-0.0-0.00.8
Reaction time mean AUC0.40.61.50.1-0.9-1.01.1-1.1-1.0-1.1-0.6-1.21.2-0.9-0.9-0.1-0.5-0.8-0.60.3-0.3-0.3-0.3-0.31.0
Median of all reaction times0.30.51.00.3-0.9-1.01.0-1.0-0.9-0.9-0.7-1.01.0-0.7-0.7-0.6-0.2-0.5-0.30.5-0.0-0.0-0.0-0.00.7
Reaction time omissions0.10.10.40.7-0.6-0.50.5-0.4-0.4-0.4-0.1-0.40.3-0.4-0.3-0.3-0.3-0.2-0.40.2-0.2-0.1-0.1-0.1-0.3
Reaction time false alarm rate4.76.512.02.4-3.4-3.53.4-3.4-3.4-3.2-2.8-3.33.2-2.9-2.7-1.9-1.8-2.1-1.91.5-0.9-0.9-0.9-0.91.9
Reaction time premature initiation rate0.50.81.3-0.40.70.9-1.01.01.01.11.01.1-0.91.01.10.10.91.10.90.20.80.80.80.8-0.1
Reaction time premature initiations0.71.22.7-1.41.61.5-1.51.51.51.40.81.4-1.21.21.11.00.80.71.0-0.80.30.30.30.30.1
Std. dev. reaction times0.30.61.21.1-1.1-1.11.0-1.0-1.0-0.9-0.1-1.01.0-0.9-0.7-0.2-0.5-0.5-0.90.5-0.2-0.2-0.2-0.20.7
Reaction time trials completed0.71.34.5-1.61.81.4-1.11.10.90.5-0.30.7-0.70.2-0.11.9-0.7-0.8-0.1-2.1-1.3-1.3-1.3-1.30.0
Reaction time trials AUC0.51.03.3-1.41.61.3-1.01.00.90.5-0.20.7-0.70.2-0.01.7-0.5-0.6-0.0-1.8-1.1-1.1-1.1-1.1-0.0
Run reversals in cocaine runway, females1.61.63.1-0.20.70.9-1.01.01.11.31.21.0-1.21.41.5-0.61.71.61.30.91.81.81.81.8-0.2
Run reversals in cocaine runway, males0.70.71.7-0.5-0.5-0.50.4-0.4-0.4-0.1-0.6-0.60.30.20.3-1.31.10.51.01.21.31.31.31.30.9
Latency to leave start box in cocaine runway0.10.10.60.10.10.2-0.20.20.30.30.80.3-0.30.40.30.20.20.3-0.10.10.20.20.20.2-0.0
Latency to leave start box in cocaine runway, F0.50.61.3-0.9-0.0-0.40.5-0.5-0.4-0.7-0.1-0.70.6-0.5-0.90.8-0.8-1.1-0.8-0.7-1.0-1.0-1.0-1.00.7
Latency to leave start box in cocaine runway, M2.11.94.21.40.30.9-1.11.11.21.51.61.6-1.41.31.8-0.71.42.10.91.01.71.71.71.7-1.1
Std. dev. time between licks in bursts0.20.20.50.70.00.1-0.00.0-0.1-0.1-0.60.1-0.1-0.4-0.30.2-0.7-0.4-0.3-0.6-0.7-0.7-0.7-0.7-0.7
Total sessions with >9 infusions0.30.41.50.90.30.4-0.50.50.30.30.80.5-0.7-0.00.10.8-0.60.0-0.7-0.7-0.7-0.7-0.7-0.7-1.2
Short access day 1 total inactive lever presses0.40.52.51.60.10.5-0.50.50.50.61.30.9-1.20.40.60.3-0.10.7-0.5-0.00.00.00.00.0-1.5
Short access day 10 total inactive lever presses0.10.30.80.5-0.10.1-0.20.20.30.50.20.5-0.50.40.6-0.70.70.80.60.70.90.90.90.9-0.0
Short access day 1 total infusions0.30.41.00.9-0.4-0.30.3-0.3-0.5-0.50.1-0.20.1-0.6-0.60.4-0.9-0.5-1.0-0.4-0.8-0.8-0.8-0.8-0.5
Short access day 10 total infusions0.40.41.2-0.40.90.9-0.90.90.80.81.10.9-1.00.70.60.70.40.50.2-0.50.10.10.10.1-0.5
Short access total infusions0.30.31.30.30.50.6-0.70.70.60.71.10.8-0.80.60.70.40.30.7-0.0-0.20.20.20.20.2-0.8
Short access day 1 locomotion0.30.30.90.40.10.1-0.10.1-0.1-0.2-0.00.0-0.1-0.4-0.40.7-0.8-0.5-0.7-0.8-1.0-1.0-1.0-1.0-0.7
Short access day 10 total locomotion1.12.06.20.51.41.6-1.51.51.41.12.51.7-1.90.70.62.1-0.70.3-1.0-1.6-1.1-1.1-1.1-1.1-2.0
Short access total locomotion1.11.33.90.01.00.9-0.80.80.60.31.20.8-0.9-0.1-0.22.0-1.2-0.6-1.2-1.8-1.7-1.7-1.7-1.7-1.3
One hour access (0.3 mA shock)0.20.20.60.40.40.5-0.50.60.40.40.50.6-0.70.20.20.5-0.30.2-0.2-0.6-0.4-0.4-0.4-0.4-0.8
Compulsive drug intake0.10.20.4-0.3-0.1-0.10.1-0.10.00.1-0.5-0.10.20.20.2-0.60.50.20.60.50.60.60.60.60.5
One hour access (shock baseline)0.10.20.70.40.30.5-0.50.50.40.40.70.6-0.70.20.20.5-0.20.2-0.3-0.5-0.3-0.3-0.3-0.3-0.8
Social response proportion1.71.94.0-0.0-1.1-1.51.6-1.6-1.7-1.8-0.9-2.01.8-1.5-1.80.3-1.3-1.8-1.6-0.2-1.2-1.2-1.2-1.20.7
Social responses0.91.23.20.4-0.4-0.60.7-0.7-1.0-1.0-0.0-0.90.8-1.1-1.31.3-1.4-1.4-1.8-0.9-1.4-1.4-1.4-1.40.3
Social time0.81.23.90.11.21.1-0.90.90.70.40.80.8-0.90.0-0.22.0-1.0-0.6-1.1-1.8-1.4-1.4-1.4-1.4-1.1
Soleus weight0.82.43.81.0-1.3-1.51.7-1.7-1.8-1.9-1.9-1.81.7-1.9-2.00.1-1.7-1.9-1.6-0.5-1.5-1.5-1.5-1.50.5
Bone: stiffness0.50.81.20.8-0.7-0.80.9-0.8-1.0-1.0-0.9-0.90.9-1.1-1.00.1-1.1-1.0-1.0-0.3-0.9-0.9-0.9-0.90.2
Tibialis anterior weight1.13.78.01.7-2.8-2.82.6-2.6-2.3-2.2-2.2-2.42.3-1.7-1.5-2.4-0.4-0.8-0.32.10.40.50.50.52.2
Time to tail flick, vehicle, before self-admin0.30.41.4-1.21.00.8-0.70.70.70.50.70.5-0.30.60.30.90.2-0.00.1-0.7-0.1-0.1-0.1-0.1-0.9
Time to tail flick, vehicle, after self-admin0.20.20.7-0.50.70.7-0.60.60.70.60.10.5-0.50.60.50.20.40.30.5-0.20.20.20.20.2-0.8
Time to tail flick, test, before self-admin0.20.20.8-0.60.60.6-0.50.50.50.40.90.4-0.40.10.30.80.10.1-0.2-0.5-0.1-0.1-0.1-0.1-0.2
Time to tail flick, test, after self-admin1.11.23.2-1.31.81.7-1.61.61.31.30.71.3-1.11.10.91.30.30.50.7-1.4-0.2-0.2-0.2-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.30.31.00.9-0.6-0.50.6-0.6-0.5-0.5-1.0-0.50.5-0.5-0.5-0.5-0.4-0.4-0.20.3-0.2-0.2-0.2-0.2-0.2
Delta time to tail flick, test, before/after SA0.10.11.4-0.40.30.2-0.20.20.10.1-1.20.0-0.10.20.0-0.20.0-0.00.8-0.3-0.1-0.1-0.1-0.10.5
Tibia length0.51.45.72.4-2.0-1.51.2-1.2-1.0-0.7-0.5-0.60.6-0.5-0.1-2.10.20.60.02.00.90.90.90.90.0
Ambulatory time before self-admin0.00.10.4-0.6-0.2-0.30.2-0.2-0.3-0.10.2-0.40.30.2-0.0-0.20.30.0-0.10.30.30.30.30.30.0
Ambulatory time after self-admin0.10.21.01.0-0.6-0.50.4-0.4-0.3-0.3-0.6-0.10.4-0.3-0.1-0.7-0.00.10.20.50.20.20.20.2-0.5
Bone: tissue strength0.10.10.4-0.60.40.2-0.10.10.0-0.0-0.2-0.10.0-0.1-0.20.5-0.2-0.4-0.2-0.6-0.5-0.4-0.4-0.4-0.0
Total heroin consumption0.20.20.6-0.50.80.8-0.70.70.60.60.60.6-0.70.50.40.60.20.10.1-0.5-0.0-0.0-0.0-0.0-0.0
Bone: trabecular number0.91.47.0-2.62.11.6-1.41.41.31.00.70.8-0.80.80.51.80.1-0.20.4-1.7-0.6-0.7-0.7-0.70.3
Bone: trabecular spacing0.60.92.41.3-1.5-1.31.2-1.2-0.9-0.8-0.7-0.80.9-0.5-0.4-1.50.20.00.11.40.70.70.70.70.4
Bone: trabecular thickness1.11.43.9-1.71.91.6-1.41.41.21.00.91.1-1.20.70.42.0-0.2-0.1-0.1-1.9-0.8-0.9-0.9-0.9-0.5
Bone: trabecular tissue density1.01.53.01.7-1.4-1.31.3-1.3-1.5-1.4-1.2-1.21.3-1.5-1.4-0.3-1.4-1.1-1.4-0.0-1.0-1.0-1.0-1.0-0.0
Water consumed over 24 hours0.10.20.6-0.70.60.5-0.40.40.20.2-0.80.2-0.2-0.0-0.00.4-0.2-0.20.5-0.8-0.5-0.5-0.5-0.50.1
Number of responses in last shaping day0.00.00.40.7-0.2-0.10.1-0.1-0.1-0.10.00.0-0.2-0.0-0.1-0.1-0.20.0-0.20.0-0.1-0.1-0.1-0.1-0.5