Hub : Genes

LOC120094685

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL intron excision ratio chr9_62337994_62370408 0.19 0.14 9.2e-03 0.06 0.04 0.05 0.03 1.5e-02 4.1e-02 2.0e-02 5.7e-02
2 NAcc isoform ratio XR_010054978.1 0.03 0.03 7.9e-03 0 0 0 0 4.3e-02 2.4e-01 3.7e-01 2.0e-01
3 IL gene expression LOC120094685 0.46 0.21 1.6e-06 0.15 0.12 0.15 0.14 2.0e-04 7.5e-04 1.6e-04 3.3e-04
4 Brain gene expression LOC120094685 0.13 0.15 1.8e-07 0.08 0.04 0.08 0.08 4.2e-08 2.4e-04 5.1e-08 1.3e-07
5 Adipose alternative TSS XR_010054979.1 0.03 0.03 8.1e-04 0.02 0.02 0.01 0.02 3.0e-03 4.1e-03 8.9e-03 5.6e-03
6 PL alternative TSS XR_010054979.1 0.03 0.03 2.1e-03 0.01 0.01 0.01 0 6.8e-02 1.4e-02 5.6e-02 1.2e-01
7 OFC gene expression LOC120094685 0.39 0.19 3.4e-05 0.07 0 0.02 0.04 9.5e-03 2.6e-01 1.1e-01 3.9e-02
8 PL gene expression LOC120094685 0.22 0.1 0.0e+00 0.23 0.22 0.22 0.22 1.3e-24 4.2e-23 1.5e-23 3.4e-23
9 Liver gene expression LOC120094685 0.1 0.08 7.2e-09 0.03 0.03 0.04 0.03 9.9e-05 9.9e-05 6.6e-05 1.4e-04
10 Adipose gene expression LOC120094685 0.1 0.06 5.1e-12 0.1 0.06 0.08 0.08 5.4e-11 9.5e-08 1.8e-09 2.3e-09
11 IC gene expression LOC120094685 0.09 0.06 5.8e-04 0.04 0.09 0.06 0.06 1.2e-02 1.1e-04 1.7e-03 1.1e-03
12 PL intron excision ratio chr9_62337994_62370636 0.02 0.02 9.6e-03 0 0 0 0 2.1e-01 8.9e-02 1.9e-01 2.7e-01
13 pVTA gene expression LOC120094685 0.08 0.07 1.1e-03 0.02 0.03 0.02 0.02 1.2e-02 3.6e-03 5.6e-03 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density2.95.08.21.9-2.92.82.92.02.12.72.02.32.01.91.8-1.5
Area under the delay curve0.80.92.1-0.70.5-0.5-1.0-1.3-1.0-0.9-1.2-0.7-0.4-1.4-1.40.3
BMI with tail4.314.821.4-4.44.2-4.3-3.4-3.7-4.1-3.4-3.5-4.2-4.6-2.9-2.64.0
BMI without tail0.41.12.5-1.61.2-1.2-0.4-0.9-1.2-0.4-0.8-1.0-1.4-0.5-0.31.6
Body weight1.45.97.72.0-2.32.32.72.72.52.72.82.42.02.72.7-1.4
Weight adjusted by age0.91.33.11.6-1.81.70.80.40.90.40.50.91.5-0.1-0.3-1.8
Bone surface2.54.67.01.8-2.62.52.62.02.02.62.02.21.91.91.9-1.4
Bone volume3.05.39.32.0-3.02.92.92.02.12.72.02.32.21.81.7-1.7
Breakpoint value in progressive ratio session1.01.12.60.8-0.30.30.91.51.11.31.50.90.41.61.6-0.3
Number of licking bursts0.20.30.6-0.60.4-0.4-0.5-0.7-0.6-0.8-0.6-0.20.0-0.7-0.70.3
Context. condit. distance diff. score2.12.54.4-2.11.9-1.8-1.4-1.5-1.7-1.3-1.5-1.4-1.8-1.0-0.91.9
Locomotion velocity, session 12.02.23.5-1.11.8-1.8-1.9-1.3-1.3-1.8-1.3-1.7-1.4-1.3-1.20.9
Locomotion distance, session 10.91.22.5-1.51.4-1.4-0.8-0.7-1.0-0.6-0.7-1.1-1.5-0.2-0.11.6
Locomotion velocity, session 22.63.04.3-1.72.1-2.0-1.9-1.7-1.8-1.7-1.7-1.7-1.6-1.4-1.31.6
Locomotion distance, session 20.10.20.4-0.30.6-0.6-0.10.2-0.1-0.10.2-0.3-0.50.40.50.6
Locomotion velocity, session 30.40.41.4-0.40.2-0.20.60.60.20.60.60.0-0.51.11.20.9
Locomotion distance, session 30.10.10.3-0.00.3-0.4-0.10.40.20.00.4-0.3-0.60.50.60.2
Stereotopy head waving bouts, day 30.60.71.7-0.91.3-1.3-0.7-0.5-0.6-0.7-0.4-0.9-1.1-0.2-0.10.9
Stereotopy head waving duration, day 30.20.30.7-0.60.8-0.8-0.1-0.0-0.3-0.20.0-0.5-0.80.30.40.8
Locomotion velocity, session 73.53.84.7-2.02.0-2.0-2.2-2.1-2.1-2.1-2.1-1.9-1.6-1.9-1.81.6
Locomotion distance, session 70.30.30.8-0.90.6-0.5-0.4-0.6-0.7-0.3-0.7-0.2-0.3-0.4-0.40.9
Stereotopy head waving bouts, day 70.20.20.70.20.5-0.6-0.60.10.0-0.70.1-0.8-0.7-0.0-0.0-0.2
Stereotopy head waving duration, day 70.20.30.7-0.20.7-0.9-0.5-0.0-0.2-0.6-0.0-0.8-0.90.10.10.3
Locomotion velocity, session 83.13.75.5-1.61.6-1.7-2.3-2.1-2.0-2.3-2.1-2.1-1.5-2.2-2.21.1
Locomotion distance, session 81.52.24.2-2.02.0-1.9-1.3-1.1-1.5-1.1-1.1-1.3-1.7-0.5-0.32.1
Degree of sensitization distance0.20.20.6-0.3-0.20.4-0.0-0.6-0.5-0.0-0.60.40.6-0.7-0.70.1
Degree of sensitization stereotypy0.10.10.40.30.2-0.3-0.40.10.1-0.50.1-0.6-0.4-0.0-0.1-0.3
Conditioned locomotion4.04.65.82.4-2.32.32.22.22.42.12.22.02.11.91.7-2.1
Cocaine response after cond. corrected1.61.95.41.9-1.81.90.71.01.40.80.91.01.70.1-0.1-2.3
Cocaine response after cond. not corrected1.61.95.21.8-1.81.90.80.81.30.80.71.11.8-0.0-0.3-2.3
Cocaine response before conditioning0.30.40.5-0.70.7-0.6-0.5-0.7-0.7-0.5-0.7-0.2-0.2-0.6-0.60.6
Saline control response0.20.21.0-0.40.4-0.30.40.2-0.10.50.10.40.00.70.81.0
Bone: connectivity density1.01.53.00.9-1.71.71.60.91.01.50.91.31.30.70.7-0.9
Bone: cortical apparent density6.18.312.2-3.53.0-2.9-2.4-3.0-3.2-2.4-2.9-3.0-3.2-2.3-2.13.2
Bone: cortical area0.20.30.60.4-0.20.10.60.60.50.50.60.2-0.10.80.8-0.1
Bone: cortical porosity3.23.43.91.9-1.81.91.91.92.01.92.01.91.91.71.6-1.7
Bone: cortical porosity5.45.96.92.4-2.52.52.62.52.62.52.62.42.32.22.1-2.1
Bone: cortical thickness0.81.42.8-1.11.4-1.5-0.9-1.0-1.0-1.3-0.9-1.5-1.7-0.7-0.61.1
Bone: cortical thickness1.61.93.6-0.81.4-1.4-1.7-1.3-1.1-1.9-1.2-1.7-1.4-1.5-1.50.2
Bone: cortical tissue density6.08.211.9-3.53.0-2.9-2.4-3.0-3.2-2.4-2.9-2.9-3.2-2.3-2.13.2
Condit. Reinf. active minus inactive responses1.11.31.81.4-1.21.20.91.21.31.11.21.01.10.90.8-1.3
Condit. Reinf. active-inactive response ratio0.60.61.21.1-0.91.00.60.70.80.70.70.70.80.40.3-1.1
Condit. Reinf. active responses1.41.72.61.5-1.51.51.01.21.41.21.21.31.60.90.8-1.4
Condit. Reinf. inactive responses0.10.10.40.3-0.40.30.20.40.30.30.40.40.60.30.3-0.2
Incentive salience index mean1.01.22.11.4-1.51.40.80.91.10.90.90.91.30.50.4-1.5
Condit. Reinf. lever presses0.30.50.90.8-1.00.90.50.50.60.50.50.71.00.20.1-0.9
Condit. Reinf. active minus inactive responses3.74.88.92.7-2.72.71.71.82.21.71.82.22.90.90.6-3.0
Condit. Reinf. active-inactive response ratio2.12.57.92.3-2.02.00.61.01.60.61.01.22.10.0-0.2-2.8
Condit. Reinf. active responses1.11.63.41.5-1.61.70.90.91.21.00.81.31.80.30.1-1.8
Condit. Reinf. inactive responses0.40.61.5-1.10.9-0.9-0.5-0.6-0.9-0.4-0.7-0.5-0.7-0.3-0.21.2
Condit. Reinf. lever presses0.50.71.8-0.60.3-0.3-0.9-1.0-0.9-0.8-1.0-0.6-0.2-1.3-1.30.1
Condit. Reinf. lever reinforcers received1.01.43.11.4-1.61.60.80.81.10.80.81.21.80.20.0-1.7
Conditioned reinforcement - actives0.50.91.9-1.00.7-0.81.00.70.01.10.90.2-0.61.21.41.4
Conditioned reinforcement - inactives0.20.20.6-0.50.3-0.30.40.40.20.60.50.60.20.70.80.4
Conditioned locomotion0.50.72.9-1.30.7-0.80.80.2-0.40.60.3-0.2-0.90.80.91.7
Patch foraging indifference point 0 sec0.91.73.8-1.00.9-1.0-1.9-1.4-1.4-1.5-1.3-1.1-0.9-1.5-1.50.8
Patch foraging indifference point AUC0.20.20.50.1-0.70.70.1-0.4-0.10.1-0.40.40.7-0.6-0.6-0.4
Delay disc. indifference point, 0s delay2.22.43.9-2.01.9-1.8-1.4-1.4-1.7-1.2-1.5-1.5-1.7-1.0-0.91.8
Delay disc. indifference point, 16s delay0.20.30.8-0.30.1-0.1-0.5-0.7-0.5-0.5-0.6-0.30.0-0.8-0.90.0
Delay disc. indifference point, 2s delay0.60.61.4-0.30.5-0.4-1.0-0.9-0.7-0.9-1.0-0.7-0.4-1.1-1.2-0.1
Delay disc. indifference point, 24s delay0.10.20.2-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.30.3
Delay disc. indifference point, 4s delay2.62.73.8-1.81.4-1.4-1.6-1.9-1.9-1.6-1.8-1.6-1.4-1.8-1.81.3
Delay disc. indifference point, 8s delay0.20.20.60.3-0.50.5-0.2-0.5-0.1-0.1-0.40.20.6-0.7-0.8-0.6
Indifference point function ln k0.91.53.2-0.70.9-1.0-1.8-1.3-1.1-1.6-1.2-1.4-1.0-1.5-1.50.3
Indifference point function log k0.91.53.2-0.70.9-1.0-1.8-1.3-1.1-1.6-1.2-1.4-1.0-1.5-1.50.3
Patch foraging total patch changes 0 sec0.81.53.1-1.01.0-1.0-1.8-1.3-1.3-1.4-1.2-1.0-0.8-1.4-1.30.8
Patch foraging total patch changes 12 sec0.00.00.1-0.2-0.10.1-0.0-0.1-0.20.2-0.10.2-0.0-0.0-0.00.3
Patch foraging total patch changes 18 sec1.72.65.1-1.51.4-1.4-2.2-1.8-1.7-1.7-1.8-1.2-1.0-1.7-1.71.1
Patch foraging total patch changes 24 sec0.10.10.3-0.40.2-0.2-0.5-0.4-0.50.1-0.4-0.1-0.2-0.3-0.30.5
Patch foraging total patch changes 6 sec1.21.93.8-1.10.7-0.8-1.4-1.8-1.5-1.4-1.8-1.1-0.7-1.9-1.90.6
Patch foraging time to switch 0 sec0.30.72.30.10.1-0.21.11.00.60.71.00.4-0.21.41.50.4
Patch foraging water rate 0 sec0.10.10.40.2-0.00.2-0.4-0.3-0.2-0.1-0.40.10.4-0.5-0.6-0.3
Patch foraging water rate 12 sec0.51.12.5-0.40.6-0.5-1.2-1.2-0.9-1.4-1.2-1.0-0.5-1.5-1.6-0.1
Patch foraging water rate 18 sec0.00.10.30.5-0.30.30.10.10.2-0.00.1-0.10.1-0.1-0.1-0.5
Patch foraging water rate 24 sec0.10.20.40.30.2-0.00.60.40.40.40.30.50.40.40.4-0.3
Patch foraging water rate 6 sec0.30.40.7-0.50.4-0.4-0.6-0.7-0.7-0.6-0.8-0.8-0.6-0.9-0.90.4
Seeking ratio, delayed vs. immediate footshock1.92.33.11.8-1.41.41.31.61.71.41.71.61.51.51.4-1.4
Distance traveled before self-admin2.53.34.41.9-1.51.61.52.12.01.72.11.81.81.91.9-1.5
Distance traveled after self-admin0.10.10.30.50.1-0.0-0.40.30.3-0.20.30.10.30.0-0.0-0.6
Extensor digitorum longus weight2.59.714.7-3.83.5-3.6-2.5-2.9-3.4-2.7-2.8-3.2-3.7-2.0-1.73.8
Bone: elastic displacement0.30.31.10.7-0.30.3-0.6-0.20.1-0.3-0.3-0.10.5-0.7-0.9-1.0
Bone: elastic work1.41.83.01.4-1.71.71.31.11.31.51.11.31.50.90.8-1.3
Bone: endosteal estimation4.19.011.23.0-3.23.22.93.13.13.43.03.12.92.82.6-2.5
Bone: endosteal perimeter2.96.28.12.6-2.82.82.62.52.62.82.42.52.32.12.0-2.2
Epididymis fat weight0.62.13.41.3-1.21.21.81.71.61.51.71.20.91.71.6-1.0
Delta time in closed arm before/after self-admin0.30.30.6-0.40.5-0.5-0.7-0.6-0.5-0.8-0.6-0.5-0.4-0.6-0.60.2
Delta time in open arm before/after self-admin6.76.610.53.2-3.13.22.32.12.72.12.12.73.11.41.2-3.1
Diff in mean of infusions in LGA sessions0.00.00.0-0.1-0.20.2-0.10.10.00.20.10.0-0.20.20.20.2
Delay discount exponential model param0.70.71.90.5-0.30.30.91.20.90.81.10.60.21.31.4-0.1
Extinction: sum of active levers before priming1.01.12.50.5-0.50.41.11.41.11.21.40.80.31.61.6-0.1
Active lever presses in extinction session 61.71.72.61.1-1.21.21.61.41.31.61.41.31.11.41.4-0.7
Bone: final force3.25.28.21.8-1.91.92.72.62.32.72.62.11.52.82.9-0.9
Bone: final moment2.64.27.31.6-1.71.62.42.42.02.42.31.91.32.72.7-0.6
Food consumed during 24 hour testing period0.20.31.4-0.70.3-0.40.40.2-0.20.40.10.0-0.50.70.81.2
Glucose0.40.72.9-1.10.9-0.90.40.1-0.30.40.20.1-0.80.91.11.7
Heart weight0.20.31.40.9-0.40.3-0.2-0.00.3-0.6-0.1-0.10.5-0.5-0.6-1.2
Delay discount hyperbolic model param0.70.82.10.5-0.40.41.01.31.00.91.20.60.31.41.4-0.1
Intermittent access intake day 1-15 change0.91.83.8-1.91.9-1.9-1.0-0.9-1.3-0.8-0.8-1.2-1.5-0.5-0.41.8
Intermittent access intake escalation1.12.34.5-2.02.1-2.1-1.3-1.1-1.5-1.1-1.0-1.5-1.7-0.7-0.61.9
Intermittent access intake escalation 20.20.20.7-0.80.8-0.7-0.3-0.2-0.4-0.3-0.1-0.4-0.4-0.00.00.7
Intermitt. access day 1 inactive lever presses1.03.911.5-3.42.7-2.6-0.4-0.9-1.8-0.7-0.8-1.8-2.7-0.10.23.2
Intermitt. access day 15 inactive lever presses0.71.42.4-1.51.1-1.0-1.1-1.5-1.4-1.2-1.1-0.9-0.7-1.4-1.40.9
Intermitt. access escalation Index0.10.20.60.3-0.50.60.8-0.10.1-0.2-0.10.20.6-0.4-0.5-0.7
Intermittent access day 1 total infusions1.83.05.50.7-1.21.32.22.01.52.32.01.71.02.32.3-0.1
Intermittent access day 15 total infusions0.60.92.8-1.30.8-0.90.50.6-0.10.80.7-0.1-0.91.21.31.7
Intermittent access terminal intake (last 3 days)0.81.03.3-1.51.0-1.00.50.5-0.20.70.7-0.2-1.01.21.31.8
Intermittent access total infusions1.31.54.2-0.4-0.20.11.41.40.81.71.51.00.11.92.10.9
Intermittent access day 1 locomotion0.70.92.10.1-0.50.41.31.20.71.21.10.6-0.01.41.40.4
Intermittent access day 15 total locomotion0.20.41.6-0.90.3-0.40.60.5-0.10.60.5-0.1-0.70.80.91.2
Intermittent access total locomotion0.50.62.0-1.10.5-0.70.60.4-0.20.60.4-0.1-0.80.91.01.4
Intermittent access standard deviation0.40.82.4-1.51.2-1.3-0.50.0-0.50.10.2-0.5-1.10.50.61.6
Left kidney weight0.10.30.90.8-0.70.80.60.40.50.00.30.30.60.0-0.1-0.9
Right kidney weight0.00.00.10.2-0.30.3-0.00.00.1-0.20.0-0.3-0.1-0.1-0.2-0.3
Cocaine induced anxiety1.01.44.4-0.2-0.10.3-1.2-1.7-1.0-1.2-1.7-0.70.1-2.0-2.1-0.5
Post-drug Anxiety1.61.84.2-0.70.4-0.4-1.3-1.8-1.3-1.5-1.8-1.2-0.6-2.0-2.10.1
Baseline Anxiety0.00.00.10.1-0.0-0.10.30.30.2-0.00.3-0.1-0.10.30.3-0.0
Tail length10.340.149.66.3-7.07.06.56.26.56.56.16.97.05.45.1-5.5
Length with tail11.851.257.67.2-7.57.67.57.47.57.27.27.67.46.56.1-6.1
Length without tail4.012.715.93.8-3.43.53.74.04.03.33.93.53.33.53.3-3.2
Times rat made contact with spout0.30.31.0-0.2-0.10.10.70.60.30.80.50.60.10.91.00.6
Lifetime Intake1.01.33.7-0.60.3-0.31.41.20.51.41.30.6-0.31.81.91.1
Liver weight, left2.74.57.11.7-1.61.62.72.52.22.22.52.11.52.72.7-1.0
Liver weight, right1.52.63.41.8-1.91.91.51.51.71.41.61.71.71.21.0-1.8
Locomotor activity0.20.30.4-0.60.3-0.3-0.5-0.6-0.6-0.5-0.5-0.4-0.4-0.6-0.60.5
Locomotor testing distance0.30.61.8-0.5-0.0-0.1-0.5-1.1-0.9-0.8-1.0-0.4-0.1-1.3-1.30.2
Locomotor testing rearing0.10.20.4-0.60.1-0.10.1-0.6-0.6-0.2-0.5-0.2-0.2-0.5-0.50.6
Locomotion in novel chamber1.82.22.8-1.51.4-1.4-1.3-1.6-1.6-1.6-1.7-1.6-1.5-1.5-1.51.3
Locomotion in novel chamber post-restriction0.40.71.0-0.70.8-0.8-1.0-0.9-0.9-0.7-0.9-0.8-0.8-0.8-0.80.6
Fecal boli incidents, locomotor time 10.30.51.10.7-1.00.9-0.0-0.50.1-0.1-0.50.20.8-0.9-1.0-1.0
Change in fecal boli incidents, locomotor task0.10.10.20.2-0.20.2-0.4-0.3-0.1-0.2-0.2-0.00.2-0.4-0.5-0.4
Time >=10cm from walls, locomotor time 11.21.33.90.9-0.70.7-1.1-1.0-0.2-1.2-1.0-0.30.8-1.8-2.0-1.7
Bouts of movement, locomotor time 10.20.30.90.2-0.50.5-0.4-0.6-0.3-0.2-0.6-0.10.3-0.9-1.0-0.4
Total resting periods, locomotor time 10.70.82.4-0.5-0.10.1-0.8-1.3-0.9-0.7-1.2-0.7-0.2-1.5-1.50.0
Rest time, locomotor task time 10.30.41.1-0.0-0.30.31.10.50.40.90.60.60.10.80.90.3
Distance moved, locomotor task time 10.20.31.10.7-0.60.7-0.4-0.30.1-0.4-0.2-0.00.6-0.8-0.9-1.0
Vertical activity count, locomotor time 10.10.30.9-0.40.6-0.6-0.9-0.5-0.5-0.8-0.3-0.7-0.5-0.6-0.60.1
Time >=10cm from walls, locomotor time 21.21.74.51.9-1.81.80.70.71.20.50.71.31.80.1-0.1-2.1
Bouts of movement, locomotor time 21.42.23.2-1.41.0-1.1-1.2-1.8-1.7-1.4-1.8-1.6-1.5-1.7-1.71.2
Total resting periods, locomotor time 21.42.43.4-1.51.1-1.2-1.3-1.8-1.7-1.5-1.8-1.7-1.6-1.7-1.71.2
Rest time, locomotor task time 20.10.10.2-0.40.1-0.10.2-0.4-0.40.1-0.4-0.2-0.4-0.2-0.20.4
Distance moved, locomotor task time 20.20.31.00.7-0.50.6-0.30.00.3-0.30.10.20.7-0.4-0.5-1.0
Vertical activity count, locomotor time 20.20.30.5-0.70.7-0.7-0.5-0.2-0.5-0.5-0.1-0.6-0.7-0.1-0.00.7
Light reinforcement 10.82.06.8-2.11.7-1.9-0.4-0.4-1.1-0.5-0.4-1.1-2.10.40.72.6
Light reinforcement 20.60.92.30.2-0.80.61.01.10.91.01.21.10.51.51.50.1
Bone: marrow area3.88.410.62.9-3.13.12.83.03.03.32.93.02.82.72.5-2.4
Bone: maximum diameter0.40.71.21.1-0.70.70.71.01.00.90.90.80.70.80.7-0.9
Bone: maximum force4.37.710.62.4-2.62.63.23.02.93.23.12.62.03.13.1-1.5
Bone: maximum moment3.56.28.82.1-2.32.33.02.72.52.92.72.31.72.92.9-1.2
Mean time between licks in bursts0.30.62.1-1.40.8-1.0-0.3-0.6-0.9-0.4-0.5-0.4-0.8-0.2-0.01.4
Mean num. licks in bursts0.20.41.00.3-0.30.30.70.80.51.00.60.3-0.10.91.00.2
Cd content in liver0.50.61.30.5-0.60.71.10.80.71.00.70.80.60.90.9-0.2
Co content in liver0.00.00.1-0.10.4-0.3-0.20.1-0.0-0.1-0.1-0.1-0.20.10.20.2
Cu content in liver0.50.61.00.9-1.00.90.40.80.80.70.70.80.90.50.5-0.8
Fe content in liver1.21.52.31.0-1.41.41.31.11.11.51.11.31.11.11.1-0.7
K content in liver0.20.20.70.1-0.20.2-0.3-0.4-0.2-0.5-0.5-0.20.1-0.7-0.8-0.5
Mg content in liver0.10.10.40.3-0.40.4-0.1-0.20.1-0.2-0.20.00.4-0.5-0.5-0.6
Mn content in liver2.73.04.5-1.71.3-1.3-1.5-2.1-1.9-1.8-2.1-1.7-1.4-2.1-2.11.1
Na content in liver0.00.00.20.3-0.20.20.10.00.1-0.0-0.1-0.10.1-0.2-0.3-0.5
Rb content in liver1.21.42.7-0.80.7-0.7-1.1-1.4-1.2-1.3-1.4-1.3-1.0-1.6-1.60.4
Se content in liver0.00.00.10.1-0.40.30.20.10.10.2-0.00.30.30.10.1-0.0
Sr content in liver2.82.44.40.9-1.11.12.01.81.51.91.91.50.92.02.1-0.3
Zn content in liver0.70.81.20.6-1.00.91.00.90.81.10.80.90.71.01.0-0.2
Bone: minimum diameter0.91.62.11.4-1.21.21.41.41.41.51.31.20.91.31.2-1.1
Time in familiar zone, hab. session 10.60.61.1-0.81.0-1.0-0.6-0.6-0.8-0.6-0.7-0.9-1.0-0.4-0.30.9
Time in novel zone, hab. session 11.21.22.81.6-0.90.90.51.21.40.61.21.01.30.80.7-1.7
Total zone transitions, hab. session 10.30.41.4-0.10.6-0.7-1.1-0.5-0.4-1.2-0.5-0.7-0.3-0.7-0.8-0.2
Total locomotion distance, hab. session 10.60.81.61.3-1.00.90.40.81.00.40.80.91.20.50.4-1.3
Locomotion velocity, hab. session 10.91.32.11.2-1.21.10.91.21.21.01.21.31.51.00.9-1.1
Time in familiar zone, hab. session 20.30.30.90.00.1-0.1-0.6-0.6-0.4-0.7-0.6-0.4-0.1-0.9-1.0-0.3
Time in novel zone, hab. session 20.60.61.60.4-0.20.20.81.00.80.91.00.70.41.21.3-0.0
Total zone transitions, hab. session 20.10.20.6-0.20.4-0.40.10.40.20.30.40.1-0.20.70.80.5
Total locomotion distance, hab. session 22.02.64.21.1-1.11.21.71.81.62.01.81.91.42.02.0-0.5
Locomotion velocity, hab. session 21.72.34.10.9-0.91.01.71.71.42.01.71.81.22.02.0-0.3
Novel to familiar place preference ratio7.48.110.42.5-2.52.52.93.23.03.03.13.22.83.13.1-1.9
Novelty place preference7.17.610.22.4-2.32.32.83.12.92.93.03.22.83.13.0-1.8
Time in novel zone, NPP test7.27.710.32.6-2.22.32.63.13.02.83.13.22.83.13.0-2.0
Total zone transitions, NPP test0.20.30.9-0.60.9-0.9-0.6-0.1-0.3-0.5-0.1-0.3-0.40.10.10.6
Total locomotion distance, NPP test0.50.71.30.7-0.50.50.60.90.90.70.91.11.10.90.8-0.7
Locomotion velocity, NPP test0.20.30.70.2-0.40.40.60.60.50.60.60.80.70.70.7-0.1
Intraocular pressure1.31.92.8-1.41.6-1.7-1.5-1.3-1.4-1.3-1.4-1.4-1.5-1.1-1.01.3
Delta distance traveled before/after self-admin0.80.91.1-1.01.0-0.9-1.0-0.9-1.0-0.8-0.9-1.0-1.1-0.8-0.80.9
Delta ambulatory time before/after self-admin0.60.71.1-1.10.8-0.8-0.7-0.9-1.0-0.6-0.9-0.9-1.0-0.7-0.61.0
Parametrial fat weight0.20.41.2-0.61.1-1.0-0.00.1-0.2-0.30.2-0.3-0.80.50.60.9
Pavlov. Cond. lever latency0.70.92.1-1.21.4-1.4-0.6-0.5-0.8-0.5-0.5-0.8-1.30.00.11.3
Pavlov. Cond. magazine entry latency0.81.13.91.4-1.41.40.30.50.90.20.50.71.4-0.3-0.5-2.0
Pavlov. Cond. change in total contacts0.40.41.10.7-1.01.00.1-0.00.30.10.00.30.8-0.5-0.6-1.1
Pavlov. Cond. index score0.91.12.81.4-1.51.50.70.71.00.60.70.91.40.1-0.1-1.7
Pavlov. Cond. latency score1.01.33.11.4-1.61.60.70.61.00.70.70.91.50.0-0.1-1.7
Pavlov. Cond. lever contacts0.50.61.71.0-1.31.20.60.40.60.50.40.61.0-0.0-0.1-1.1
Pavlov. Cond. magazine entry number1.21.53.3-1.51.6-1.6-0.8-0.9-1.2-0.7-0.9-1.1-1.5-0.3-0.21.8
Pavlov. Cond. intertrial magazine entries1.01.21.80.9-1.01.01.31.11.01.31.11.21.21.21.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.82.41.2-1.41.30.40.40.70.30.40.61.2-0.2-0.4-1.6
Pavlov. Cond. response bias0.91.12.61.4-1.41.40.60.81.00.60.80.91.30.20.1-1.6
Pavlov. Cond. lever latency0.81.12.40.9-0.50.51.11.31.21.21.30.70.21.51.6-0.4
Pavlov. Cond. magazine entry latency0.40.40.7-0.80.7-0.7-0.3-0.6-0.7-0.6-0.6-0.8-0.8-0.4-0.30.8
Pavlov. Cond. change in total contacts0.20.30.90.4-0.1-0.0-0.7-0.4-0.1-0.9-0.4-0.50.1-0.8-0.9-0.8
Pavlov. Cond. index score0.30.40.7-0.50.5-0.5-0.7-0.8-0.7-0.8-0.7-0.6-0.4-0.8-0.80.3
Pavlov. Cond. latency score0.20.30.5-0.40.4-0.4-0.5-0.6-0.5-0.7-0.5-0.5-0.3-0.6-0.60.2
Pavlov. Cond. lever contacts0.60.92.6-0.60.2-0.2-1.0-1.2-1.0-1.0-1.2-0.60.1-1.5-1.60.0
Pavlov. Cond. magazine entry number0.00.00.20.00.3-0.2-0.5-0.1-0.1-0.2-0.1-0.1-0.1-0.2-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.80.2-0.2-0.4-0.8-0.9-0.3-0.9-0.3-0.2-0.8-0.80.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.0-0.50.5-0.5-0.8-0.9-0.7-0.9-0.8-0.8-0.4-1.0-1.00.2
Pavlov. Cond. response bias0.20.30.8-0.3-0.10.1-0.4-0.7-0.5-0.5-0.6-0.20.2-0.9-0.9-0.0
Time in closed arm before self-admin2.02.64.32.0-2.02.11.51.21.61.31.21.72.00.90.7-1.8
Time in closed arm after self-admin0.40.41.10.5-0.40.4-0.6-0.6-0.2-0.7-0.60.00.6-0.9-1.1-0.8
Time in open arm before self-admin4.44.89.2-3.03.0-3.0-1.6-1.3-2.0-1.5-1.2-2.3-3.0-0.5-0.33.0
Time in open arm after self-admin1.41.62.11.4-1.41.41.21.21.41.11.21.21.30.90.9-1.4
Bone: periosteal estimation2.75.76.92.5-2.42.42.42.62.62.62.52.32.12.32.2-2.0
Bone: periosteal perimeter2.34.04.82.1-2.12.02.12.12.22.22.11.91.61.91.8-1.7
Bone: post-yield work1.31.83.10.9-1.11.11.71.51.41.61.61.20.71.71.8-0.4
Progressive ratio test 1 active lever presses0.20.20.5-0.70.1-0.20.00.3-0.00.70.50.0-0.40.60.70.7
Progressive ratio test 1 breakpoint0.20.20.6-0.4-0.00.00.10.40.20.80.60.2-0.20.70.70.5
Progressive ratio test 1 inactive lever presses1.82.79.2-3.02.1-2.10.4-0.4-1.20.1-0.1-0.9-2.00.60.82.9
Progressive ratio test 2 active lever presses0.60.72.3-0.4-0.10.01.01.00.50.91.10.5-0.11.41.50.7
Progressive ratio test 2 breakpoint0.60.72.1-0.5-0.1-0.00.91.00.40.91.00.5-0.11.31.40.7
Progressive ratio test 2 inactive lever presses0.40.61.5-1.00.4-0.50.80.60.10.90.80.4-0.31.11.21.1
Incentive Sensitization - Responses0.50.71.10.4-1.00.91.00.70.70.90.91.01.00.80.8-0.4
Incentive Sensitization - Breakpoint0.50.61.00.3-0.90.81.00.70.70.90.91.00.90.80.9-0.3
Sum of active levers in priming session hrs 5-63.63.35.01.6-1.21.22.22.21.92.12.21.71.22.22.2-0.9
Progressive ratio0.10.20.4-0.20.6-0.6-0.6-0.5-0.4-0.5-0.4-0.6-0.6-0.4-0.40.2
Food seeking constrained by brief footshock0.30.30.90.7-0.50.5-0.5-0.20.0-0.5-0.40.20.8-0.7-0.8-0.9
Seeking ratio, punishment vs. effort0.40.61.80.7-1.21.20.30.30.50.30.10.91.3-0.1-0.2-1.0
Retroperitoneal fat weight0.31.13.2-1.10.6-0.61.20.80.10.80.90.2-0.81.61.81.7
Reaction time number correct0.40.82.1-0.91.1-1.2-0.9-0.3-0.7-0.7-0.4-1.1-1.4-0.2-0.11.0
Reaction time mean minus median2.15.27.51.8-2.02.02.72.32.22.52.32.72.42.42.4-1.3
Reaction time mean minus median AUC1.53.84.91.7-1.71.72.12.12.01.92.12.22.02.12.1-1.3
Reaction time num false alarms2.63.77.8-2.62.3-2.3-1.1-1.5-2.1-1.3-1.6-1.9-2.5-0.9-0.72.8
Reaction time num false alarms AUC2.43.88.9-2.62.5-2.5-1.1-1.4-2.0-1.2-1.4-1.8-2.6-0.6-0.43.0
Reaction time trials correct on left0.40.82.1-0.91.1-1.2-0.9-0.3-0.7-0.7-0.4-1.1-1.4-0.2-0.11.0
Reaction time trials on left0.30.61.9-0.91.0-1.1-0.8-0.2-0.6-0.6-0.3-1.0-1.4-0.00.11.0
Reaction time mean6.810.913.52.8-3.02.93.63.63.43.43.63.73.33.63.5-2.1
Reaction time mean AUC6.410.213.42.5-2.72.73.63.53.33.43.53.53.03.73.6-1.7
Median of all reaction times6.99.812.32.8-2.82.73.23.53.33.23.53.43.03.43.4-2.1
Reaction time omissions2.13.15.41.1-1.41.32.12.11.72.02.11.61.12.32.3-0.5
Reaction time false alarm rate1.21.74.3-1.81.5-1.5-0.6-1.1-1.5-0.7-1.2-1.1-1.5-0.6-0.52.1
Reaction time premature initiation rate2.13.07.8-0.30.4-0.4-2.3-2.1-1.3-2.3-2.0-1.6-0.4-2.6-2.8-0.7
Reaction time premature initiations1.83.36.4-0.81.1-1.1-2.5-2.0-1.6-2.5-1.9-2.1-1.3-2.3-2.40.1
Std. dev. reaction times4.38.010.62.5-2.82.83.12.92.93.02.93.33.02.82.8-1.9
Reaction time trials completed0.30.61.9-0.91.0-1.1-0.8-0.2-0.6-0.6-0.3-1.0-1.4-0.00.11.0
Reaction time trials AUC0.40.72.0-0.91.1-1.2-0.8-0.2-0.6-0.6-0.3-1.0-1.4-0.00.11.0
Run reversals in cocaine runway, females0.20.20.30.4-0.60.6-0.10.50.40.50.20.40.40.30.3-0.4
Run reversals in cocaine runway, males0.30.30.70.1-0.20.2-0.8-0.6-0.3-0.5-0.5-0.4-0.1-0.8-0.8-0.3
Latency to leave start box in cocaine runway4.45.08.4-2.62.9-2.9-2.2-2.0-2.3-2.1-1.8-2.3-2.5-1.6-1.42.3
Latency to leave start box in cocaine runway, F3.23.66.1-2.02.5-2.4-2.1-1.7-1.9-1.9-1.4-2.0-2.1-1.4-1.31.7
Latency to leave start box in cocaine runway, M2.72.53.3-1.81.7-1.7-1.5-1.6-1.7-1.5-1.6-1.6-1.6-1.4-1.31.6
Std. dev. time between licks in bursts1.21.72.4-1.51.5-1.5-1.4-1.4-1.4-1.2-1.2-1.0-1.0-1.1-1.11.2
Total sessions with >9 infusions0.60.72.4-1.31.1-1.10.40.1-0.40.30.1-0.4-1.10.60.81.6
Short access day 1 total inactive lever presses0.50.62.1-1.41.0-0.90.40.1-0.40.40.3-0.1-0.60.60.71.4
Short access day 10 total inactive lever presses0.30.83.1-1.81.3-1.2-0.4-0.4-0.8-0.4-0.2-0.5-0.8-0.10.01.3
Short access day 1 total infusions0.60.71.8-1.00.5-0.51.40.80.20.70.70.1-0.61.21.31.1
Short access day 10 total infusions1.51.94.8-0.1-0.30.41.71.50.92.01.61.20.32.12.20.8
Short access total infusions0.60.82.2-0.60.6-0.51.20.90.30.90.90.3-0.51.41.51.1
Short access day 1 locomotion0.30.41.0-0.80.5-0.50.70.40.00.70.50.1-0.50.91.01.0
Short access day 10 total locomotion0.71.33.1-1.81.4-1.3-0.6-0.6-1.1-0.5-0.7-1.2-1.6-0.3-0.11.7
Short access total locomotion0.91.13.7-1.61.3-1.30.3-0.0-0.70.2-0.1-0.8-1.60.50.71.9
One hour access (0.3 mA shock)0.91.12.7-0.40.10.01.21.10.61.61.31.00.21.51.60.8
Compulsive drug intake1.31.62.7-1.31.1-1.0-0.7-1.7-1.4-1.2-1.5-1.1-0.9-1.6-1.60.7
One hour access (shock baseline)1.72.66.20.6-0.70.71.52.11.52.22.11.50.72.42.50.2
Social response proportion2.42.73.51.8-1.61.61.61.91.81.51.81.61.61.71.6-1.3
Social responses0.60.81.90.6-0.20.30.71.31.00.71.30.70.41.31.4-0.2
Social time1.01.32.81.7-0.90.90.51.31.40.51.31.01.40.90.7-1.7
Soleus weight0.00.10.2-0.0-0.40.40.2-0.4-0.20.1-0.30.20.4-0.4-0.4-0.1
Bone: stiffness4.06.510.41.9-2.12.13.12.92.53.02.92.41.63.23.2-0.9
Tibialis anterior weight0.93.04.5-2.11.7-1.8-1.3-1.8-1.9-1.5-1.7-1.9-2.1-1.3-1.21.9
Time to tail flick, vehicle, before self-admin0.10.10.40.4-0.50.50.60.30.30.50.30.30.20.30.3-0.3
Time to tail flick, vehicle, after self-admin0.40.50.60.7-0.70.70.50.70.70.70.70.80.80.70.7-0.6
Time to tail flick, test, before self-admin0.70.71.4-1.20.9-0.9-0.6-0.8-0.9-0.5-0.8-0.8-1.0-0.5-0.41.1
Time to tail flick, test, after self-admin0.90.91.6-1.31.0-1.0-1.0-0.9-1.1-0.9-0.9-1.0-0.9-0.8-0.81.0
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.30.4-0.3-0.20.0-0.1-0.1-0.0-0.0-0.10.10.10.3
Delta time to tail flick, test, before/after SA0.10.10.20.1-0.00.0-0.4-0.2-0.1-0.4-0.2-0.10.2-0.4-0.4-0.4
Tibia length5.314.718.03.6-3.73.74.24.24.14.24.13.83.24.03.9-2.8
Ambulatory time before self-admin1.82.64.01.6-1.11.21.52.01.81.62.01.61.51.91.9-1.2
Ambulatory time after self-admin0.10.10.3-0.20.6-0.5-0.30.1-0.1-0.10.2-0.2-0.40.20.20.3
Bone: tissue strength1.71.73.60.7-0.90.91.71.41.21.71.51.30.81.81.9-0.1
Total heroin consumption1.72.05.80.60.1-0.11.42.01.31.41.91.00.12.32.40.2
Bone: trabecular number1.42.34.51.0-2.12.02.11.31.31.91.31.41.11.31.2-0.8
Bone: trabecular spacing0.50.71.5-0.10.8-0.8-1.2-0.8-0.6-1.2-0.8-0.6-0.1-1.1-1.1-0.2
Bone: trabecular thickness0.91.12.10.9-1.51.41.40.90.91.30.91.00.80.80.8-0.7
Bone: trabecular tissue density0.20.20.7-0.3-0.10.10.70.30.10.70.30.3-0.10.70.80.8
Water consumed over 24 hours0.30.41.5-1.20.4-0.40.1-0.6-0.8-0.0-0.5-0.4-0.7-0.2-0.11.2
Number of responses in last shaping day0.40.41.8-0.81.4-1.1-0.2-0.0-0.40.00.0-0.2-0.80.30.41.0