Hub : Genes

LOC120094678

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr9_44623199_44676041 0.06 0.04 2.5e-05 0.03 0.04 0.05 0.04 4.1e-04 7.3e-05 3.7e-05 5.2e-05
2 NAcc gene expression LOC120094678 0.2 0.09 0.0e+00 0.14 0.14 0.15 0.15 3.1e-16 1.7e-16 4.4e-17 1.2e-16
3 Brain intron excision ratio chr9_44623199_44624206 0.04 0.03 3.3e-03 0.01 0 0.01 0.01 8.7e-02 1.2e-01 5.5e-02 3.5e-02
4 pVTA gene expression LOC120094678 0.19 0.1 1.6e-07 0.09 0.14 0.13 0.11 1.1e-04 1.8e-06 3.4e-06 1.8e-05
5 BLA gene expression LOC120094678 0.15 0.08 9.9e-07 0.09 0.1 0.11 0.11 2.3e-05 7.8e-06 1.1e-06 1.4e-06
6 PL gene expression LOC120094678 0.38 0.1 0.0e+00 0.32 0.41 0.41 0.41 1.2e-36 2.3e-48 7.0e-48 6.4e-49
7 Brain gene expression LOC120094678 0.33 0.15 0.0e+00 0.24 0.22 0.23 0.24 2.7e-22 1.1e-20 5.2e-21 8.4e-22
8 IL gene expression LOC120094678 0.43 0.17 2.3e-04 0.18 0.12 0.16 0.17 4.7e-05 6.8e-04 1.5e-04 7.5e-05
9 OFC intron excision ratio chr9_44601496_44602201 0.25 0.13 4.9e-03 0.01 0.02 0.02 0.03 1.8e-01 1.3e-01 1.4e-01 7.8e-02
10 OFC gene expression LOC120094678 0.55 0.14 5.7e-08 0.29 0.26 0.23 0.31 1.1e-07 8.0e-07 4.3e-06 3.6e-08
11 PL intron excision ratio chr9_44601496_44602201 0.08 0.04 1.8e-09 0.1 0.07 0.07 0.08 9.0e-11 4.0e-08 2.6e-08 7.6e-09
12 OFC intron excision ratio chr9_44542424_44602201 0.25 0.14 5.2e-03 0.05 0.02 0.02 0.03 2.3e-02 9.3e-02 1.2e-01 6.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density4.06.710.8-2.92.7-3.3-2.62.7-2.62.62.62.3-2.8-2.40.4
Area under the delay curve0.50.54.3-0.1-0.10.60.1-0.00.3-0.4-0.4-0.40.70.0-2.1
BMI with tail1.75.47.22.5-2.72.42.5-2.42.4-2.3-2.3-2.42.42.3-0.5
BMI without tail0.00.10.2-0.20.3-0.5-0.30.1-0.40.40.40.1-0.3-0.0-0.1
Body weight0.10.41.40.6-0.8-0.10.7-0.80.5-0.5-0.5-0.80.51.20.0
Weight adjusted by age1.71.93.41.6-1.61.01.7-1.61.3-1.1-1.1-1.81.01.60.3
Bone surface0.91.62.3-1.41.2-1.5-1.21.5-1.11.11.11.3-1.2-1.50.7
Bone volume2.44.16.5-2.42.0-2.5-2.02.3-1.91.91.92.0-2.1-2.20.6
Breakpoint value in progressive ratio session0.20.21.2-0.80.1-1.1-0.30.50.2-0.3-0.30.50.1-0.10.1
Number of licking bursts0.50.61.3-0.71.0-0.3-0.80.8-0.80.70.70.7-0.5-1.1-0.4
Context. condit. distance diff. score1.01.22.4-1.01.1-1.5-1.00.6-1.31.31.30.4-1.5-0.3-0.8
Locomotion velocity, session 10.20.21.70.2-0.10.10.2-0.5-0.10.00.0-0.7-0.10.6-1.3
Locomotion distance, session 12.33.05.41.9-1.61.21.9-2.31.5-1.5-1.5-2.31.32.3-0.8
Locomotion velocity, session 23.54.15.02.2-2.21.92.2-2.22.1-2.1-2.1-2.21.82.0-0.3
Locomotion distance, session 22.53.64.32.0-1.91.92.0-2.02.1-2.1-2.1-1.91.91.7-0.1
Locomotion velocity, session 30.10.10.20.0-0.2-0.50.1-0.30.1-0.1-0.1-0.3-0.10.50.0
Locomotion distance, session 30.00.00.2-0.2-0.0-0.4-0.10.10.1-0.2-0.20.30.0-0.10.4
Stereotopy head waving bouts, day 30.30.30.8-0.90.5-0.7-0.60.9-0.30.30.30.6-0.4-0.7-0.2
Stereotopy head waving duration, day 30.10.10.6-0.50.3-0.3-0.30.4-0.20.10.10.1-0.2-0.2-0.8
Locomotion velocity, session 71.71.94.01.8-1.31.11.6-2.01.0-0.8-0.8-2.00.71.8-0.3
Locomotion distance, session 70.81.01.91.2-0.81.01.1-1.30.8-0.8-0.8-1.40.80.9-0.7
Stereotopy head waving bouts, day 70.20.20.7-0.3-0.3-0.50.20.10.4-0.5-0.5-0.30.00.5-0.8
Stereotopy head waving duration, day 70.20.21.1-0.0-0.2-0.60.3-0.30.2-0.2-0.2-0.6-0.41.0-0.5
Locomotion velocity, session 80.40.51.50.8-0.5-0.10.7-1.10.10.00.0-1.2-0.41.2-0.3
Locomotion distance, session 80.60.92.31.1-0.70.31.0-1.50.5-0.5-0.5-1.50.11.5-0.3
Degree of sensitization distance1.21.22.41.2-0.91.41.1-1.30.8-0.7-0.7-1.50.90.9-1.6
Degree of sensitization stereotypy0.10.10.4-0.1-0.3-0.50.3-0.10.2-0.3-0.3-0.4-0.10.7-0.4
Conditioned locomotion0.80.91.9-1.40.9-1.2-1.01.3-0.70.60.61.1-0.7-1.0-0.5
Cocaine response after cond. corrected0.10.10.60.00.10.60.00.10.1-0.1-0.1-0.00.5-0.2-0.8
Cocaine response after cond. not corrected0.10.10.60.2-0.20.50.3-0.30.2-0.2-0.2-0.40.50.2-0.8
Cocaine response before conditioning0.60.81.60.8-1.0-0.01.1-1.10.8-0.7-0.7-1.20.41.3-0.1
Saline control response0.20.20.80.6-0.30.20.6-0.70.10.00.0-0.8-0.20.9-0.0
Bone: connectivity density1.42.13.3-1.81.5-1.8-1.51.7-1.31.31.31.5-1.3-1.70.2
Bone: cortical apparent density3.95.27.82.8-2.52.12.7-2.72.2-1.9-1.9-2.51.82.50.8
Bone: cortical area0.00.10.1-0.1-0.4-0.30.30.10.3-0.3-0.3-0.10.0-0.10.1
Bone: cortical porosity1.01.11.7-1.21.0-1.3-1.11.2-1.00.90.91.1-1.1-1.20.4
Bone: cortical porosity1.31.42.3-1.11.3-1.5-1.21.0-1.41.41.40.9-1.5-0.90.2
Bone: cortical thickness0.00.10.20.0-0.4-0.30.4-0.10.4-0.4-0.4-0.30.00.1-0.1
Bone: cortical thickness0.10.10.4-0.20.1-0.40.10.0-0.20.30.3-0.3-0.40.0-0.6
Bone: cortical tissue density3.85.07.72.8-2.52.12.6-2.62.1-1.9-1.9-2.51.82.50.8
Condit. Reinf. active minus inactive responses1.31.511.70.2-0.40.40.6-0.80.6-0.8-0.8-1.20.70.9-3.4
Condit. Reinf. active-inactive response ratio1.41.514.3-0.00.10.20.4-0.80.2-0.3-0.3-1.20.31.1-3.8
Condit. Reinf. active responses0.91.17.20.3-0.60.30.8-0.80.7-0.8-0.8-1.30.60.9-2.7
Condit. Reinf. inactive responses0.81.01.70.9-1.30.71.1-0.81.2-1.2-1.2-1.10.90.7-0.1
Incentive salience index mean0.50.76.4-0.10.1-0.10.3-0.40.1-0.1-0.1-0.9-0.00.6-2.5
Condit. Reinf. lever presses0.30.41.1-0.40.7-0.8-0.30.2-0.80.80.8-0.1-1.10.0-0.4
Condit. Reinf. active minus inactive responses0.40.55.0-0.70.3-0.5-0.40.2-0.1-0.1-0.10.0-0.10.0-2.2
Condit. Reinf. active-inactive response ratio1.11.12.6-1.41.1-1.1-1.21.0-0.90.80.80.8-0.9-0.9-1.6
Condit. Reinf. active responses0.30.43.2-0.1-0.40.10.3-0.30.5-0.6-0.6-0.40.50.4-1.8
Condit. Reinf. inactive responses0.91.01.51.2-1.20.91.2-1.21.0-0.9-0.9-1.10.91.20.2
Condit. Reinf. lever presses0.10.21.2-0.50.1-0.4-0.10.3-0.0-0.1-0.10.1-0.2-0.0-1.1
Condit. Reinf. lever reinforcers received0.40.64.10.1-0.50.30.4-0.40.6-0.7-0.7-0.60.60.5-2.0
Conditioned reinforcement - actives0.30.33.00.20.10.1-0.0-0.40.2-0.4-0.4-0.40.30.0-1.7
Conditioned reinforcement - inactives0.30.30.70.3-0.4-0.20.5-0.50.7-0.8-0.8-0.50.50.5-0.8
Conditioned locomotion0.91.12.51.2-0.80.40.9-1.61.0-1.1-1.1-1.20.81.3-0.8
Patch foraging indifference point 0 sec0.30.52.00.9-0.90.40.8-0.60.6-0.4-0.4-0.30.60.51.4
Patch foraging indifference point AUC0.60.71.40.7-0.81.10.7-0.41.0-1.1-1.1-0.31.20.3-0.4
Delay disc. indifference point, 0s delay0.90.92.51.4-0.60.71.0-1.60.5-0.4-0.4-1.60.41.4-0.2
Delay disc. indifference point, 16s delay0.91.03.6-1.11.2-0.5-1.00.8-1.00.80.80.5-0.5-0.8-1.9
Delay disc. indifference point, 2s delay0.30.30.70.2-0.50.40.3-0.20.6-0.7-0.7-0.30.90.1-0.8
Delay disc. indifference point, 24s delay0.20.21.3-0.00.40.0-0.1-0.2-0.40.40.4-0.3-0.20.3-1.1
Delay disc. indifference point, 4s delay0.50.51.30.7-0.40.80.7-0.80.5-0.5-0.5-1.10.60.8-1.1
Delay disc. indifference point, 8s delay0.30.32.1-0.3-0.10.50.00.30.3-0.4-0.4-0.10.6-0.2-1.5
Indifference point function ln k0.20.30.80.9-0.30.80.5-0.80.2-0.1-0.1-0.40.40.60.6
Indifference point function log k0.20.30.80.9-0.30.80.5-0.80.2-0.1-0.1-0.40.40.60.6
Patch foraging total patch changes 0 sec0.30.41.60.8-0.80.50.7-0.50.6-0.4-0.4-0.20.70.31.3
Patch foraging total patch changes 12 sec0.10.20.90.3-0.5-0.30.4-0.20.3-0.2-0.2-0.10.10.41.0
Patch foraging total patch changes 18 sec0.60.81.90.7-1.11.20.8-0.31.1-1.1-1.1-0.01.40.10.2
Patch foraging total patch changes 24 sec0.40.41.40.8-0.80.50.7-0.50.7-0.5-0.5-0.30.60.31.2
Patch foraging total patch changes 6 sec0.20.30.70.3-0.60.40.40.10.7-0.6-0.60.30.8-0.10.8
Patch foraging time to switch 0 sec0.30.51.0-0.70.5-0.9-0.70.7-0.70.70.70.7-0.8-0.51.0
Patch foraging water rate 0 sec0.20.41.40.3-0.50.70.5-0.30.7-0.7-0.7-0.40.90.0-1.2
Patch foraging water rate 12 sec0.10.10.5-0.1-0.10.7-0.00.30.1-0.0-0.00.20.2-0.70.1
Patch foraging water rate 18 sec0.10.10.2-0.2-0.3-0.20.30.30.5-0.4-0.40.10.5-0.50.4
Patch foraging water rate 24 sec0.00.10.20.2-0.20.40.2-0.30.2-0.1-0.1-0.30.40.4-0.0
Patch foraging water rate 6 sec0.10.21.00.3-0.21.00.10.20.3-0.4-0.40.30.6-0.50.3
Seeking ratio, delayed vs. immediate footshock0.60.71.2-0.60.9-1.1-0.80.4-1.01.01.00.4-1.1-0.3-0.5
Distance traveled before self-admin0.90.91.6-0.51.0-0.6-1.00.7-1.21.21.20.9-1.3-0.90.9
Distance traveled after self-admin1.92.13.5-1.11.4-1.9-1.31.0-1.51.61.61.1-1.7-0.91.6
Extensor digitorum longus weight6.324.733.75.8-5.55.85.5-5.05.2-4.9-4.9-4.65.04.51.0
Bone: elastic displacement1.01.13.2-1.30.7-0.7-1.21.6-0.60.50.51.6-0.3-1.80.5
Bone: elastic work1.01.32.0-1.41.1-1.2-1.21.4-1.01.01.01.2-1.1-1.4-0.1
Bone: endosteal estimation0.10.30.5-0.50.6-0.4-0.60.6-0.60.50.50.6-0.4-0.70.2
Bone: endosteal perimeter0.00.10.2-0.40.1-0.3-0.30.5-0.10.10.10.4-0.2-0.40.0
Epididymis fat weight0.10.30.70.4-0.90.10.6-0.40.8-0.7-0.7-0.30.70.50.3
Delta time in closed arm before/after self-admin0.50.41.1-0.2-0.9-0.10.50.31.0-1.1-1.10.00.7-0.20.6
Delta time in open arm before/after self-admin2.01.93.2-1.01.7-0.5-1.51.2-1.81.81.81.3-1.5-1.3-0.2
Diff in mean of infusions in LGA sessions0.91.02.2-1.50.8-1.3-1.11.4-0.70.60.61.3-0.6-1.00.3
Delay discount exponential model param0.40.44.10.2-0.1-0.60.1-0.1-0.20.30.30.2-0.60.12.0
Extinction: sum of active levers before priming2.12.13.1-1.71.5-1.7-1.71.6-1.41.31.31.8-1.2-1.60.2
Active lever presses in extinction session 60.60.61.50.3-0.70.60.5-0.31.0-1.2-1.2-0.21.20.3-0.9
Bone: final force0.10.10.30.3-0.2-0.20.4-0.40.00.10.1-0.6-0.30.50.1
Bone: final moment0.00.10.30.3-0.2-0.20.4-0.30.10.00.0-0.5-0.20.40.1
Food consumed during 24 hour testing period0.70.81.20.8-0.90.80.9-1.00.9-0.9-0.9-1.10.81.1-0.9
Glucose0.50.71.5-0.90.8-0.4-1.01.1-0.70.70.71.2-0.4-1.10.5
Heart weight0.50.71.50.9-1.11.00.8-0.90.8-0.7-0.7-0.81.20.60.2
Delay discount hyperbolic model param0.50.53.7-0.10.2-0.9-0.30.2-0.40.60.60.5-0.9-0.21.9
Intermittent access intake day 1-15 change0.20.20.50.20.2-0.2-0.1-0.2-0.60.70.7-0.3-0.30.0-0.3
Intermittent access intake escalation0.50.51.2-0.20.7-0.7-0.40.0-1.01.11.1-0.2-0.7-0.0-1.0
Intermittent access intake escalation 20.40.40.9-0.40.6-0.5-0.50.2-0.80.90.90.2-0.50.1-1.0
Intermitt. access day 1 inactive lever presses0.60.61.0-0.50.8-1.0-0.60.5-0.70.80.80.8-0.8-0.71.0
Intermitt. access day 15 inactive lever presses0.00.00.20.0-0.1-0.1-0.00.20.00.00.00.1-0.1-0.40.5
Intermitt. access escalation Index0.30.20.8-0.0-0.70.10.4-0.20.4-0.4-0.4-0.5-0.20.7-0.9
Intermittent access day 1 total infusions0.30.41.8-0.4-0.0-0.3-0.10.20.5-0.8-0.80.00.8-0.4-1.3
Intermittent access day 15 total infusions0.20.32.0-0.40.4-0.6-0.40.2-0.20.10.10.00.1-0.4-1.4
Intermittent access terminal intake (last 3 days)0.20.31.6-0.1-0.2-0.30.1-0.10.4-0.6-0.6-0.30.7-0.1-1.3
Intermittent access total infusions0.20.21.2-0.40.2-0.4-0.30.20.1-0.3-0.30.10.5-0.5-1.1
Intermittent access day 1 locomotion0.10.10.40.2-0.1-0.10.1-0.30.4-0.6-0.6-0.20.40.2-0.3
Intermittent access day 15 total locomotion0.30.30.70.5-0.30.30.4-0.60.5-0.6-0.6-0.70.60.5-0.8
Intermittent access total locomotion0.30.30.60.5-0.30.10.4-0.70.6-0.8-0.8-0.60.60.6-0.6
Intermittent access standard deviation1.51.62.8-1.31.5-1.7-1.51.2-1.31.21.21.4-1.0-1.3-0.3
Left kidney weight0.20.62.00.6-1.20.10.8-0.40.9-0.8-0.8-0.50.70.61.4
Right kidney weight0.30.83.80.9-1.0-0.60.8-0.90.30.10.1-0.9-0.01.12.0
Cocaine induced anxiety4.65.37.52.2-2.71.82.5-2.12.7-2.7-2.7-2.12.02.40.8
Post-drug Anxiety4.14.58.51.3-2.61.22.2-1.52.8-2.9-2.9-1.82.12.1-0.8
Baseline Anxiety1.01.13.0-1.50.9-0.8-1.01.3-0.70.60.60.9-0.4-1.2-1.7
Tail length0.82.44.1-1.81.9-2.0-1.71.4-1.71.61.61.3-1.6-1.1-0.4
Length with tail0.20.61.9-0.80.8-1.4-0.70.5-0.70.80.80.6-0.8-0.20.5
Length without tail1.02.13.51.5-1.91.01.7-1.51.6-1.4-1.4-1.51.41.70.7
Times rat made contact with spout1.01.22.2-1.41.1-0.8-1.41.5-0.90.70.71.5-0.6-1.3-0.4
Lifetime Intake0.20.21.6-0.10.1-0.3-0.1-0.10.2-0.4-0.4-0.20.6-0.4-1.3
Liver weight, left0.30.51.9-0.50.5-0.8-0.50.6-0.50.60.60.8-0.6-0.81.4
Liver weight, right0.10.20.3-0.60.3-0.5-0.40.5-0.30.30.30.6-0.3-0.50.2
Locomotor activity0.10.10.3-0.5-0.0-0.5-0.30.40.0-0.2-0.20.6-0.0-0.20.1
Locomotor testing distance0.91.42.4-1.41.2-1.6-1.31.2-1.21.11.11.3-1.2-1.10.3
Locomotor testing rearing1.32.03.4-1.21.5-1.8-1.40.8-1.81.81.81.0-1.7-0.60.4
Locomotion in novel chamber6.17.510.12.8-3.22.73.0-2.73.0-2.9-2.9-2.62.92.7-0.3
Locomotion in novel chamber post-restriction1.51.83.11.7-1.61.81.5-1.31.4-1.3-1.3-1.11.31.00.1
Fecal boli incidents, locomotor time 10.40.42.30.8-0.21.50.4-0.60.1-0.1-0.1-0.60.70.2-1.0
Change in fecal boli incidents, locomotor task0.50.51.1-0.40.7-1.0-0.60.2-0.91.01.00.3-0.7-0.10.6
Time >=10cm from walls, locomotor time 11.91.95.51.7-1.42.31.5-1.11.3-1.3-1.3-1.21.50.7-0.2
Bouts of movement, locomotor time 14.04.47.41.6-1.92.71.7-1.52.3-2.5-2.5-1.62.71.3-2.2
Total resting periods, locomotor time 14.04.47.31.7-1.92.71.8-1.62.3-2.4-2.4-1.72.61.3-2.2
Rest time, locomotor task time 10.30.43.1-0.50.40.1-0.50.4-0.1-0.0-0.00.20.3-0.7-1.8
Distance moved, locomotor task time 11.11.22.20.6-1.50.41.3-0.71.5-1.5-1.5-0.91.21.00.3
Vertical activity count, locomotor time 10.10.10.5-0.20.1-0.70.1-0.1-0.30.40.4-0.2-0.40.50.4
Time >=10cm from walls, locomotor time 20.20.20.7-0.30.40.1-0.40.5-0.50.50.50.2-0.3-0.8-0.5
Bouts of movement, locomotor time 22.32.53.21.4-1.51.51.5-1.51.7-1.8-1.8-1.61.81.3-1.8
Total resting periods, locomotor time 22.22.43.31.4-1.51.41.4-1.41.7-1.8-1.8-1.51.71.2-1.6
Rest time, locomotor task time 20.30.40.9-0.60.7-0.3-0.70.7-0.60.40.40.8-0.3-1.0-0.3
Distance moved, locomotor task time 21.31.52.40.9-1.41.01.3-0.91.5-1.6-1.6-1.11.40.8-0.6
Vertical activity count, locomotor time 20.70.72.00.8-0.40.50.8-1.10.4-0.3-0.3-1.40.31.3-1.3
Light reinforcement 13.05.57.62.6-2.72.12.5-2.52.5-2.4-2.4-2.12.42.21.3
Light reinforcement 21.21.62.80.9-1.70.71.2-0.71.7-1.7-1.7-0.71.40.51.3
Bone: marrow area0.10.20.4-0.50.6-0.3-0.50.5-0.50.50.50.5-0.4-0.60.1
Bone: maximum diameter0.20.40.8-0.80.3-0.8-0.50.9-0.30.20.20.9-0.5-0.90.7
Bone: maximum force0.00.00.10.10.0-0.30.2-0.1-0.10.20.2-0.3-0.40.10.1
Bone: maximum moment0.00.00.10.1-0.1-0.30.2-0.1-0.00.10.1-0.3-0.30.10.1
Mean time between licks in bursts1.52.16.81.6-1.71.51.4-1.01.4-1.2-1.2-0.61.20.82.6
Mean num. licks in bursts0.20.20.50.3-0.70.30.4-0.30.6-0.7-0.7-0.20.50.60.1
Cd content in liver0.10.10.4-0.20.3-0.5-0.2-0.0-0.50.50.5-0.1-0.60.1-0.1
Co content in liver0.30.42.2-0.30.3-0.6-0.2-0.3-0.50.50.5-0.4-0.60.5-1.5
Cu content in liver0.50.74.2-0.50.8-0.8-0.4-0.2-0.60.60.6-0.4-0.80.6-2.0
Fe content in liver3.33.95.2-1.92.3-2.2-2.11.8-2.22.22.21.7-2.3-1.60.5
K content in liver0.60.61.50.7-0.90.70.7-0.30.9-0.9-0.9-0.20.50.21.2
Mg content in liver0.10.11.20.2-0.30.10.20.00.2-0.1-0.10.1-0.1-0.11.1
Mn content in liver0.40.40.90.9-0.60.90.7-0.70.6-0.5-0.5-0.60.50.60.7
Na content in liver2.12.34.2-0.71.5-1.0-1.41.0-1.92.02.01.2-1.7-1.21.5
Rb content in liver2.93.64.11.8-2.01.91.9-2.02.0-2.0-2.0-1.91.92.0-1.2
Se content in liver0.10.10.20.3-0.50.20.4-0.40.4-0.4-0.4-0.50.40.3-0.1
Sr content in liver0.20.20.4-0.10.00.5-0.20.50.1-0.1-0.10.60.4-0.60.6
Zn content in liver0.30.30.50.4-0.70.00.6-0.60.5-0.5-0.5-0.70.20.7-0.5
Bone: minimum diameter0.10.20.40.5-0.60.30.6-0.50.5-0.5-0.5-0.50.30.30.2
Time in familiar zone, hab. session 10.60.61.3-1.10.6-0.7-0.91.1-0.50.40.41.1-0.3-0.8-0.7
Time in novel zone, hab. session 10.20.20.5-0.50.5-0.4-0.40.5-0.40.40.40.3-0.4-0.70.2
Total zone transitions, hab. session 10.50.71.91.0-0.60.11.0-1.30.5-0.3-0.3-1.4-0.11.20.6
Total locomotion distance, hab. session 11.42.13.41.4-1.51.01.7-1.61.5-1.5-1.5-1.81.11.5-0.4
Locomotion velocity, hab. session 11.21.72.81.4-1.40.91.6-1.51.3-1.2-1.2-1.70.91.40.3
Time in familiar zone, hab. session 20.50.51.4-0.80.6-0.6-0.71.0-0.30.30.31.2-0.4-0.80.8
Time in novel zone, hab. session 20.10.11.10.1-0.0-0.10.1-0.3-0.20.20.2-0.6-0.10.2-1.0
Total zone transitions, hab. session 20.30.40.80.7-0.40.50.6-0.90.6-0.6-0.6-0.70.70.90.1
Total locomotion distance, hab. session 22.02.63.81.4-1.61.51.6-1.61.8-1.9-1.9-1.51.81.6-0.9
Locomotion velocity, hab. session 21.82.53.11.5-1.51.41.6-1.71.7-1.8-1.8-1.61.71.7-0.5
Novel to familiar place preference ratio0.60.71.5-1.10.7-0.3-0.91.1-0.50.40.40.9-0.2-1.2-1.2
Novelty place preference0.70.71.6-1.10.7-0.4-0.91.2-0.60.50.50.9-0.3-1.2-1.3
Time in novel zone, NPP test1.01.12.1-1.40.9-0.5-1.21.4-0.80.60.61.1-0.4-1.4-1.3
Total zone transitions, NPP test1.31.93.91.5-1.10.91.5-1.91.2-1.2-1.2-1.81.02.0-0.5
Total locomotion distance, NPP test1.72.43.01.4-1.51.21.6-1.71.7-1.7-1.7-1.71.51.7-0.8
Locomotion velocity, NPP test2.33.34.31.9-1.81.52.0-2.11.9-1.9-1.9-2.01.62.1-0.3
Intraocular pressure1.31.82.51.5-1.21.61.3-1.31.4-1.3-1.3-1.11.51.4-0.3
Delta distance traveled before/after self-admin0.10.10.6-0.0-0.2-0.50.20.00.2-0.2-0.2-0.00.10.20.8
Delta ambulatory time before/after self-admin0.10.10.50.1-0.4-0.30.3-0.10.4-0.3-0.3-0.20.40.20.7
Parametrial fat weight0.10.10.8-0.10.2-0.2-0.30.2-0.30.40.40.5-0.2-0.10.9
Pavlov. Cond. lever latency0.40.51.10.4-0.71.00.3-0.00.9-0.9-0.90.31.1-0.10.8
Pavlov. Cond. magazine entry latency0.10.10.3-0.30.4-0.2-0.20.1-0.30.30.30.1-0.3-0.0-0.5
Pavlov. Cond. change in total contacts0.30.32.4-0.00.30.0-0.0-0.2-0.30.30.3-0.5-0.20.0-1.6
Pavlov. Cond. index score0.50.60.8-0.80.9-0.8-0.70.6-0.90.80.80.3-0.9-0.4-0.8
Pavlov. Cond. latency score0.50.71.1-0.81.0-1.0-0.70.5-1.01.01.00.2-1.0-0.3-0.9
Pavlov. Cond. lever contacts0.30.40.8-0.40.7-0.7-0.40.2-0.80.80.8-0.1-0.9-0.2-0.5
Pavlov. Cond. magazine entry number0.60.81.21.1-1.00.90.9-0.80.9-0.8-0.8-0.60.90.71.0
Pavlov. Cond. intertrial magazine entries0.20.20.60.1-0.60.30.4-0.10.5-0.6-0.6-0.30.40.1-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.50.6-0.5-0.40.4-0.50.50.50.2-0.5-0.3-0.9
Pavlov. Cond. response bias0.30.40.5-0.60.7-0.6-0.60.5-0.70.70.70.3-0.7-0.5-0.5
Pavlov. Cond. lever latency0.00.10.20.3-0.00.50.1-0.10.1-0.1-0.10.00.3-0.10.4
Pavlov. Cond. magazine entry latency0.20.20.90.4-0.1-0.30.4-0.7-0.00.10.1-0.6-0.30.90.3
Pavlov. Cond. change in total contacts0.40.60.9-0.70.8-0.9-0.70.5-0.91.01.00.3-0.8-0.3-0.9
Pavlov. Cond. index score0.10.10.3-0.30.2-0.6-0.10.1-0.30.30.30.1-0.40.1-0.0
Pavlov. Cond. latency score0.00.00.1-0.1-0.0-0.30.1-0.0-0.10.10.1-0.1-0.20.20.0
Pavlov. Cond. lever contacts0.30.40.7-0.70.5-0.8-0.60.7-0.60.60.60.6-0.7-0.60.2
Pavlov. Cond. magazine entry number0.10.10.40.1-0.30.60.10.10.4-0.4-0.40.10.5-0.3-0.1
Pavlov. Cond. intertrial magazine entries2.73.54.61.8-1.92.11.8-1.82.1-2.1-2.1-1.62.11.5-1.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.10.0-0.50.0-0.0-0.20.20.2-0.1-0.30.2-0.0
Pavlov. Cond. response bias0.30.50.9-0.50.6-1.0-0.50.4-0.70.80.80.4-1.0-0.20.7
Time in closed arm before self-admin1.01.11.6-1.21.2-0.6-1.21.2-1.00.90.91.0-0.7-1.0-1.3
Time in closed arm after self-admin0.10.10.7-0.60.2-0.8-0.30.5-0.1-0.0-0.00.2-0.4-0.3-0.3
Time in open arm before self-admin1.61.72.41.3-1.51.01.5-1.21.6-1.5-1.5-1.21.61.10.6
Time in open arm after self-admin0.91.02.1-0.61.2-0.5-1.00.7-1.41.51.50.8-1.1-0.80.5
Bone: periosteal estimation0.10.30.6-0.60.5-0.7-0.50.7-0.40.40.40.5-0.5-0.70.2
Bone: periosteal perimeter0.10.20.6-0.7-0.1-0.5-0.30.80.1-0.2-0.20.6-0.1-0.7-0.0
Bone: post-yield work0.10.10.40.10.1-0.60.0-0.2-0.30.40.4-0.2-0.70.30.5
Progressive ratio test 1 active lever presses1.21.22.11.0-0.90.60.9-1.21.3-1.5-1.5-1.21.40.8-0.8
Progressive ratio test 1 breakpoint1.01.12.10.8-0.90.40.9-1.01.3-1.5-1.5-1.11.40.6-0.7
Progressive ratio test 1 inactive lever presses0.10.10.8-0.10.0-0.90.1-0.30.1-0.1-0.1-0.3-0.00.10.3
Progressive ratio test 2 active lever presses0.20.30.70.4-0.3-0.10.4-0.80.3-0.3-0.3-0.80.20.6-0.7
Progressive ratio test 2 breakpoint0.70.81.60.8-0.80.30.9-1.20.8-0.8-0.8-1.30.71.0-0.9
Progressive ratio test 2 inactive lever presses0.10.10.50.1-0.2-0.70.2-0.30.3-0.3-0.3-0.4-0.10.20.0
Incentive Sensitization - Responses0.20.20.70.10.2-0.3-0.0-0.3-0.70.80.8-0.3-0.70.20.1
Incentive Sensitization - Breakpoint0.20.20.40.3-0.0-0.10.2-0.5-0.40.60.6-0.6-0.50.40.1
Sum of active levers in priming session hrs 5-61.01.02.6-1.20.8-0.4-1.11.5-0.50.40.41.50.1-1.60.6
Progressive ratio0.60.71.80.8-0.71.30.6-0.80.6-0.6-0.6-0.51.20.8-1.2
Food seeking constrained by brief footshock0.60.72.10.2-1.30.60.9-0.21.1-1.0-1.0-0.51.40.5-0.1
Seeking ratio, punishment vs. effort0.20.31.6-0.6-0.2-0.9-0.10.70.1-0.0-0.00.3-0.1-0.51.3
Retroperitoneal fat weight0.41.43.81.4-1.20.21.3-1.80.8-0.7-0.7-1.70.62.0-0.1
Reaction time number correct0.81.22.01.3-1.11.31.2-1.30.9-0.8-0.8-1.40.81.1-0.7
Reaction time mean minus median1.11.42.3-1.31.2-1.1-1.41.5-1.11.01.01.5-0.7-1.40.9
Reaction time mean minus median AUC0.50.71.1-1.00.9-1.0-1.01.0-0.80.70.71.0-0.5-0.70.4
Reaction time num false alarms1.92.53.61.6-1.71.61.8-1.41.9-1.9-1.9-1.41.91.2-0.3
Reaction time num false alarms AUC2.02.83.61.9-1.81.81.9-1.51.9-1.9-1.9-1.41.91.30.2
Reaction time trials correct on left0.81.22.01.3-1.11.31.2-1.30.9-0.8-0.8-1.40.81.1-0.7
Reaction time trials on left0.81.11.81.2-1.11.21.2-1.30.9-0.8-0.8-1.40.71.1-0.6
Reaction time mean1.82.53.7-1.91.8-1.9-1.91.7-1.61.41.41.7-1.4-1.30.1
Reaction time mean AUC1.41.92.9-1.71.6-1.6-1.71.5-1.41.21.21.5-1.2-1.0-0.1
Median of all reaction times1.62.23.3-1.81.8-1.8-1.81.5-1.51.31.31.5-1.4-1.1-0.3
Reaction time omissions0.91.31.6-1.01.3-1.2-1.21.1-1.21.21.21.2-1.2-0.80.9
Reaction time false alarm rate0.81.11.71.1-1.10.91.1-0.81.3-1.3-1.3-0.61.30.60.6
Reaction time premature initiation rate0.00.00.2-0.30.1-0.10.00.30.0-0.1-0.10.00.0-0.2-0.5
Reaction time premature initiations0.10.20.60.2-0.40.40.5-0.30.4-0.4-0.4-0.60.40.3-0.8
Std. dev. reaction times1.82.63.8-1.71.7-1.5-1.81.8-1.61.51.51.9-1.3-1.71.0
Reaction time trials completed0.81.11.81.2-1.11.21.2-1.30.9-0.8-0.8-1.40.71.1-0.6
Reaction time trials AUC0.71.01.61.2-1.01.21.1-1.20.8-0.7-0.7-1.30.71.0-0.6
Run reversals in cocaine runway, females1.01.01.41.0-1.11.11.0-0.81.2-1.2-1.2-0.80.70.9-0.3
Run reversals in cocaine runway, males1.71.73.60.5-1.90.41.3-0.51.9-1.9-1.9-0.81.50.7-0.4
Latency to leave start box in cocaine runway2.12.34.31.9-1.61.21.8-2.01.2-1.1-1.1-2.10.81.9-0.1
Latency to leave start box in cocaine runway, F0.40.41.20.7-0.70.40.8-0.70.3-0.1-0.1-0.8-0.10.61.1
Latency to leave start box in cocaine runway, M4.34.15.82.3-2.01.92.0-2.41.9-1.9-1.9-2.21.82.3-1.3
Std. dev. time between licks in bursts0.20.21.20.4-0.40.90.20.10.2-0.2-0.20.30.4-0.31.1
Total sessions with >9 infusions1.61.82.81.3-1.21.01.2-1.51.3-1.4-1.4-1.71.71.0-1.3
Short access day 1 total inactive lever presses0.30.30.70.7-0.80.00.5-0.60.6-0.4-0.4-0.60.40.40.8
Short access day 10 total inactive lever presses0.10.10.4-0.3-0.0-0.60.10.20.2-0.2-0.20.1-0.40.20.3
Short access day 1 total infusions0.60.71.31.1-0.90.50.9-1.10.8-0.7-0.7-1.21.00.4-0.2
Short access day 10 total infusions0.91.06.1-0.3-0.5-0.10.2-0.10.9-1.2-1.2-0.61.3-0.3-2.5
Short access total infusions0.50.62.30.5-0.40.20.4-0.70.6-0.8-0.8-0.91.0-0.1-1.5
Short access day 1 locomotion0.20.20.40.6-0.50.60.4-0.40.5-0.5-0.5-0.40.7-0.1-0.2
Short access day 10 total locomotion0.10.10.2-0.10.0-0.5-0.20.10.2-0.3-0.30.20.2-0.1-0.0
Short access total locomotion0.40.40.80.8-0.60.30.6-0.80.7-0.9-0.9-0.70.70.4-0.3
One hour access (0.3 mA shock)1.61.82.9-1.71.6-1.3-1.71.4-1.20.90.91.6-0.6-1.6-1.4
Compulsive drug intake0.50.51.4-0.60.6-0.2-0.70.8-0.70.70.71.2-0.7-0.80.8
One hour access (shock baseline)0.50.63.2-1.00.7-1.0-0.80.6-0.40.10.10.4-0.1-0.6-1.8
Social response proportion0.20.20.4-0.40.6-0.2-0.50.5-0.50.50.50.4-0.4-0.50.2
Social responses0.70.91.7-1.31.0-1.3-1.01.0-0.80.80.81.0-0.7-0.70.5
Social time3.54.78.2-2.52.3-2.9-2.12.0-2.32.22.21.7-2.4-1.9-0.4
Soleus weight1.03.05.12.3-2.02.11.9-1.81.6-1.4-1.4-1.51.61.31.5
Bone: stiffness0.20.30.70.7-0.10.00.5-0.8-0.20.30.3-0.8-0.40.80.3
Tibialis anterior weight3.311.415.63.9-4.03.73.7-3.33.6-3.5-3.5-3.13.52.80.9
Time to tail flick, vehicle, before self-admin0.60.61.0-0.71.0-0.4-0.90.8-0.90.90.91.0-0.7-0.60.2
Time to tail flick, vehicle, after self-admin0.30.41.3-0.60.8-0.2-0.50.5-0.60.50.50.2-0.6-0.2-1.1
Time to tail flick, test, before self-admin2.12.13.91.5-1.22.01.5-1.31.6-1.7-1.7-1.31.41.0-0.8
Time to tail flick, test, after self-admin0.40.41.70.9-0.31.30.4-0.70.4-0.4-0.4-0.60.60.1-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.40.2-0.30.20.3-0.30.2-0.3-0.3-0.50.00.4-0.7
Delta time to tail flick, test, before/after SA1.41.32.0-1.01.1-0.9-1.31.0-1.41.41.41.0-1.0-1.2-0.3
Tibia length0.61.63.1-0.91.5-1.5-1.10.8-1.51.51.50.9-1.8-0.70.8
Ambulatory time before self-admin0.60.61.1-0.31.0-0.1-0.80.5-1.01.01.00.6-1.1-0.70.6
Ambulatory time after self-admin0.30.32.90.20.1-0.5-0.0-0.2-0.30.40.40.0-0.40.11.7
Bone: tissue strength0.30.30.50.5-0.40.30.6-0.70.4-0.4-0.4-0.70.30.7-0.6
Total heroin consumption0.40.51.4-1.20.6-0.9-0.70.9-0.20.10.10.9-0.0-0.8-0.4
Bone: trabecular number3.35.18.6-2.52.4-2.9-2.22.2-2.42.42.41.9-2.6-1.90.1
Bone: trabecular spacing2.53.35.02.2-1.62.11.9-2.21.5-1.4-1.4-2.11.72.2-0.7
Bone: trabecular thickness4.95.98.1-2.82.5-2.8-2.62.5-2.62.52.52.2-2.5-2.3-0.3
Bone: trabecular tissue density0.10.20.60.6-0.20.20.4-0.60.10.00.0-0.40.00.60.8
Water consumed over 24 hours0.30.42.80.2-0.10.30.4-0.50.2-0.2-0.2-0.70.30.5-1.7
Number of responses in last shaping day0.20.20.8-0.50.2-0.9-0.20.4-0.30.40.40.2-0.3-0.40.5