Hub : Genes

LOC120094678

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr9_52115392_52168230 0.06 0.03 2.0e-05 0.03 0.04 0.04 0.04 4.1e-04 5.8e-05 2.6e-04 2.5e-04
2 Brain intron excision ratio chr9_52115392_52116399 0.04 0.03 1.4e-03 0.01 0.02 0.02 0.02 1.5e-02 4.4e-03 4.7e-03 9.9e-03
3 PL intron excision ratio chr9_52115392_52116399 0.05 0.03 1.8e-05 0.04 0.04 0.01 0.04 5.2e-05 9.8e-05 9.0e-03 7.7e-05
4 IC intron excision ratio chr9_52093689_52094394 0.33 0.12 2.4e-13 0.24 0.28 0.26 0.27 2.1e-10 2.6e-12 3.4e-11 9.2e-12
5 PL gene expression LOC120094678 0.27 0.09 0.0e+00 0.23 0.28 0.27 0.28 4.6e-25 1.4e-30 8.5e-30 5.9e-31
6 NAcc gene expression LOC120094678 0.14 0.07 1.3e-13 0.08 0.08 0.08 0.08 3.2e-12 3.8e-12 3.5e-12 2.4e-12
7 PL isoform ratio XR_005489126.2 0.03 0.02 4.4e-03 0.01 0.01 0.01 0.01 1.2e-02 2.4e-02 4.3e-02 2.6e-02
8 BLA gene expression LOC120094678 0.14 0.09 1.6e-05 0.08 0.07 0.08 0.08 4.6e-05 1.1e-04 6.4e-05 6.9e-05
9 IC gene expression LOC120094678 0.36 0.13 5.0e-14 0.31 0.3 0.31 0.31 1.0e-13 2.6e-13 1.5e-13 1.5e-13
10 pVTA gene expression LOC120094678 0.04 0.03 3.8e-03 0.04 0.02 0.03 0.02 5.9e-04 1.3e-02 1.1e-03 5.1e-03
11 PL intron excision ratio chr9_52093689_52094394 0.08 0.04 2.0e-09 0.09 0.08 0.08 0.08 2.4e-10 9.8e-09 5.1e-09 4.0e-09
12 Brain gene expression LOC120094678 0.1 0.07 1.1e-04 0.03 0.04 0.04 0.04 1.1e-03 6.8e-05 6.1e-05 9.8e-05
13 OFC intron excision ratio chr9_52035214_52094394 0.24 0.13 9.4e-03 0 0 -0 0 2.7e-01 2.5e-01 3.4e-01 2.3e-01
14 OFC intron excision ratio chr9_52093689_52094394 0.24 0.13 8.6e-03 0 0 0 0.01 2.7e-01 2.6e-01 3.2e-01 2.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density2.95.38.42.6-2.92.22.8-2.7-2.72.22.22.32.3-2.32.2-0.70.7
Area under the delay curve0.50.74.00.20.10.8-0.50.20.3-0.4-0.3-0.2-0.20.2-0.82.0-2.0
BMI with tail0.30.91.8-1.31.3-1.3-1.21.21.3-1.0-0.6-0.6-0.60.7-1.00.2-0.2
BMI without tail0.10.31.00.5-0.20.80.1-0.2-0.00.30.60.50.5-0.5-0.51.0-1.0
Body weight0.00.10.20.3-0.20.30.2-0.2-0.10.40.30.30.3-0.30.10.1-0.1
Weight adjusted by age0.72.13.5-1.91.6-1.8-1.61.61.5-1.8-1.6-1.5-1.51.5-0.30.10.0
Bone surface0.71.32.01.0-1.10.81.3-1.1-1.11.11.31.41.4-1.40.9-0.90.8
Bone volume1.83.54.82.0-2.21.72.2-2.0-2.01.82.02.12.1-2.11.6-0.90.9
Breakpoint value in progressive ratio session0.20.41.30.8-0.51.20.6-0.2-0.00.80.80.60.5-0.4-0.5-0.20.2
Number of licking bursts0.20.61.10.8-0.70.70.7-0.8-0.70.70.81.01.0-1.00.30.3-0.4
Context. condit. distance diff. score0.70.93.01.0-1.40.71.0-1.3-1.40.30.40.40.4-0.41.70.7-0.7
Locomotion velocity, session 10.40.41.70.1-0.20.2-0.2-0.2-0.2-0.6-0.6-0.7-0.70.70.51.3-1.3
Locomotion distance, session 12.63.36.0-1.81.5-1.6-1.91.61.5-2.2-2.3-2.5-2.52.4-0.21.0-1.0
Locomotion velocity, session 23.03.65.0-2.22.2-2.1-2.22.12.0-2.2-2.2-1.8-1.81.9-1.30.6-0.5
Locomotion distance, session 22.02.94.2-2.02.1-1.7-2.02.02.0-1.8-1.8-1.7-1.71.7-1.30.3-0.2
Locomotion velocity, session 30.00.00.1-0.20.0-0.2-0.10.1-0.0-0.3-0.2-0.3-0.30.30.20.0-0.0
Locomotion distance, session 30.10.10.20.2-0.20.20.3-0.1-0.20.50.30.10.1-0.10.2-0.50.5
Stereotopy head waving bouts, day 30.40.40.90.7-0.60.80.6-0.5-0.40.50.91.01.0-1.0-0.10.1-0.1
Stereotopy head waving duration, day 30.20.30.60.6-0.50.80.3-0.4-0.20.10.50.60.6-0.6-0.20.7-0.7
Locomotion velocity, session 72.22.54.5-1.81.4-2.1-1.61.31.1-2.0-2.1-1.8-1.81.80.20.6-0.5
Locomotion distance, session 70.91.11.9-1.10.9-1.2-1.20.90.7-1.4-1.3-1.2-1.21.20.10.9-0.8
Stereotopy head waving bouts, day 70.10.20.70.1-0.20.3-0.10.10.1-0.5-0.2-0.3-0.30.3-0.20.8-0.8
Stereotopy head waving duration, day 70.20.20.6-0.2-0.1-0.2-0.20.20.2-0.8-0.6-0.8-0.80.80.20.5-0.5
Locomotion velocity, session 80.70.81.8-0.80.2-1.1-0.60.20.0-1.3-1.2-1.2-1.21.21.10.5-0.4
Locomotion distance, session 80.81.12.2-1.10.6-1.3-0.90.60.4-1.5-1.4-1.4-1.41.40.90.4-0.4
Degree of sensitization distance1.31.42.9-1.00.9-0.8-1.30.80.9-1.6-1.4-1.0-1.01.1-0.51.7-1.7
Degree of sensitization stereotypy0.20.20.4-0.20.0-0.1-0.20.30.2-0.7-0.5-0.6-0.60.6-0.10.5-0.5
Conditioned locomotion0.40.51.51.0-0.81.20.7-0.6-0.40.70.80.70.7-0.7-0.20.4-0.5
Cocaine response after cond. corrected0.10.10.70.10.10.5-0.20.00.1-0.10.20.10.1-0.1-0.40.8-0.8
Cocaine response after cond. not corrected0.20.30.9-0.20.30.1-0.60.30.3-0.6-0.2-0.4-0.40.4-0.50.9-0.9
Cocaine response before conditioning1.11.32.3-1.20.9-1.3-1.11.11.0-1.4-1.5-1.5-1.51.5-0.20.3-0.2
Saline control response0.50.61.2-0.90.6-0.9-0.70.50.4-1.1-1.0-1.1-1.11.10.40.2-0.1
Bone: connectivity density0.91.52.21.4-1.41.31.4-1.3-1.21.21.21.51.5-1.50.7-0.40.3
Bone: cortical apparent density3.55.58.9-3.02.7-3.0-2.62.62.3-2.6-2.6-2.6-2.62.6-0.8-0.40.5
Bone: cortical area0.00.00.1-0.20.1-0.2-0.10.20.2-0.3-0.10.10.1-0.10.1-0.10.1
Bone: cortical porosity1.21.31.71.2-1.20.91.3-1.2-1.21.21.21.31.3-1.30.8-0.70.6
Bone: cortical porosity1.31.42.41.3-1.50.81.4-1.5-1.51.01.01.11.1-1.11.5-0.40.4
Bone: cortical thickness0.00.00.2-0.2-0.0-0.1-0.10.20.1-0.4-0.3-0.1-0.10.10.20.1-0.1
Bone: cortical thickness0.20.20.6-0.2-0.1-0.1-0.30.1-0.0-0.8-0.5-0.3-0.30.30.50.8-0.8
Bone: cortical tissue density3.35.28.7-2.92.6-2.9-2.42.52.2-2.5-2.5-2.5-2.52.5-0.7-0.50.6
Condit. Reinf. active minus inactive responses2.12.312.0-0.00.00.6-0.90.40.6-1.3-1.5-1.0-1.01.0-0.63.5-3.5
Condit. Reinf. active-inactive response ratio2.52.714.50.3-0.40.8-0.7-0.10.1-1.3-1.5-1.0-1.01.00.03.8-3.8
Condit. Reinf. active responses1.31.77.5-0.30.20.2-1.00.50.7-1.4-1.4-0.9-0.90.9-0.62.7-2.7
Condit. Reinf. inactive responses0.60.81.3-1.01.0-0.8-1.01.11.2-1.1-0.8-0.8-0.80.8-1.10.2-0.2
Incentive salience index mean0.91.26.60.1-0.30.4-0.5-0.00.1-1.0-1.1-0.6-0.60.60.22.6-2.6
Condit. Reinf. lever presses0.10.21.10.2-0.6-0.00.3-0.5-0.5-0.2-0.2-0.1-0.10.11.00.5-0.5
Condit. Reinf. active minus inactive responses0.61.05.40.7-0.61.10.0-0.4-0.2-0.2-0.4-0.3-0.20.2-0.22.3-2.3
Condit. Reinf. active-inactive response ratio0.81.32.81.5-1.41.70.9-1.2-1.00.70.60.70.7-0.80.51.6-1.7
Condit. Reinf. active responses0.60.83.8-0.00.10.5-0.60.30.5-0.6-0.9-0.7-0.70.6-0.81.9-1.9
Condit. Reinf. inactive responses1.01.52.1-1.41.4-1.4-1.31.31.2-1.2-1.4-1.4-1.41.4-0.6-0.00.1
Condit. Reinf. lever presses0.20.31.30.5-0.50.80.2-0.3-0.20.00.10.10.1-0.1-0.11.1-1.2
Condit. Reinf. lever reinforcers received0.81.14.5-0.20.30.3-0.80.50.6-0.8-1.0-0.9-0.90.8-0.82.1-2.1
Conditioned reinforcement - actives0.10.31.5-0.20.3-0.6-0.50.20.2-0.4-0.5-0.2-0.10.2-0.31.2-1.2
Conditioned reinforcement - inactives0.30.91.7-1.10.9-1.3-1.01.01.0-1.0-1.2-1.0-0.91.0-0.20.1-0.1
Conditioned locomotion0.71.02.9-1.21.0-1.7-1.00.80.9-0.9-1.3-1.2-1.21.3-0.10.2-0.1
Patch foraging indifference point 0 sec0.20.51.4-0.90.8-1.0-0.40.70.5-0.2-0.4-0.4-0.40.4-0.1-1.11.2
Patch foraging indifference point AUC0.20.41.5-0.50.8-0.5-0.70.81.0-0.5-0.3-0.3-0.30.3-1.20.4-0.4
Delay disc. indifference point, 0s delay1.21.42.7-1.31.0-1.6-1.20.90.6-1.5-1.5-1.5-1.51.50.40.3-0.3
Delay disc. indifference point, 16s delay1.01.43.81.3-1.21.90.6-1.1-1.10.50.60.70.7-0.70.51.9-2.0
Delay disc. indifference point, 2s delay0.20.21.0-0.10.40.2-0.50.40.6-0.2-0.2-0.1-0.10.1-1.00.8-0.8
Delay disc. indifference point, 24s delay0.20.31.40.3-0.40.5-0.0-0.5-0.5-0.2-0.3-0.3-0.30.30.61.2-1.2
Delay disc. indifference point, 4s delay0.60.61.0-0.70.6-0.5-0.90.60.6-1.0-0.8-0.8-0.80.8-0.31.0-1.0
Delay disc. indifference point, 8s delay0.30.42.10.3-0.01.0-0.30.20.1-0.20.00.10.1-0.1-0.71.4-1.5
Indifference point function ln k0.10.41.0-0.90.9-1.0-0.70.60.5-0.4-0.7-0.7-0.70.70.0-0.50.5
Indifference point function log k0.10.41.0-0.90.9-1.0-0.70.60.5-0.4-0.7-0.7-0.70.70.0-0.50.5
Patch foraging total patch changes 0 sec0.10.41.1-0.80.8-0.9-0.40.60.5-0.1-0.2-0.2-0.20.2-0.4-1.01.0
Patch foraging total patch changes 12 sec0.10.20.6-0.50.2-0.6-0.10.40.2-0.3-0.3-0.3-0.30.30.3-0.80.8
Patch foraging total patch changes 18 sec0.20.41.9-0.60.9-0.5-0.50.91.00.2-0.1-0.1-0.00.1-1.4-0.30.3
Patch foraging total patch changes 24 sec0.10.41.1-0.80.7-1.0-0.40.70.5-0.3-0.3-0.2-0.10.1-0.2-1.01.0
Patch foraging total patch changes 6 sec0.10.20.6-0.40.5-0.4-0.20.50.50.10.20.20.2-0.2-0.8-0.70.7
Patch foraging time to switch 0 sec0.20.61.70.5-0.60.50.8-0.5-0.60.90.80.60.6-0.60.8-1.31.3
Patch foraging water rate 0 sec0.10.52.4-0.00.20.2-0.50.30.4-0.5-0.3-0.0-0.0-0.0-1.01.5-1.6
Patch foraging water rate 12 sec0.00.20.60.00.30.1-0.20.10.10.10.40.70.7-0.7-0.80.1-0.1
Patch foraging water rate 18 sec0.10.20.8-0.20.40.1-0.30.50.5-0.20.00.40.4-0.4-0.9-0.30.3
Patch foraging water rate 24 sec0.10.10.2-0.20.30.2-0.30.20.2-0.2-0.3-0.5-0.50.4-0.00.0-0.0
Patch foraging water rate 6 sec0.10.21.1-0.10.5-0.3-0.20.30.30.20.50.40.4-0.4-1.0-0.30.3
Seeking ratio, delayed vs. immediate footshock0.20.41.10.7-0.90.10.7-0.9-0.90.40.20.20.1-0.21.00.3-0.3
Distance traveled before self-admin0.91.92.81.2-1.40.81.6-1.6-1.71.51.21.41.5-1.51.4-1.31.2
Distance traveled after self-admin1.42.45.61.3-1.70.81.8-1.8-2.01.31.21.31.3-1.42.4-1.51.5
Extensor digitorum longus weight5.120.433.2-5.55.8-5.2-5.35.45.3-4.4-4.3-4.4-4.44.4-3.8-0.10.3
Bone: elastic displacement1.82.34.31.5-1.21.71.4-1.2-1.11.81.92.12.1-2.0-0.2-0.70.7
Bone: elastic work1.41.82.81.5-1.51.51.4-1.4-1.41.31.51.71.6-1.60.7-0.10.1
Bone: endosteal estimation0.10.30.60.5-0.40.30.5-0.5-0.50.50.70.70.7-0.70.5-0.20.2
Bone: endosteal perimeter0.00.10.30.3-0.20.20.3-0.2-0.10.40.60.50.5-0.5-0.2-0.0-0.0
Epididymis fat weight0.10.61.2-0.70.9-0.5-0.91.01.1-0.6-0.7-0.6-0.60.7-0.90.8-0.8
Delta time in closed arm before/after self-admin0.30.32.3-0.10.30.5-0.20.70.8-0.1-0.10.20.2-0.2-1.50.1-0.1
Delta time in open arm before/after self-admin1.11.32.41.1-1.20.81.2-1.5-1.51.21.01.21.1-1.21.5-0.20.1
Diff in mean of infusions in LGA sessions0.40.81.40.9-0.81.11.0-0.6-0.61.11.21.11.0-0.90.1-0.80.7
Delay discount exponential model param0.50.73.8-0.3-0.0-0.90.4-0.1-0.20.30.20.10.1-0.10.7-1.91.9
Extinction: sum of active levers before priming2.53.85.62.2-2.12.12.2-2.0-1.92.22.02.42.3-2.11.0-0.70.6
Active lever presses in extinction session 60.30.31.6-0.20.50.0-0.50.70.9-0.1-0.1-0.2-0.20.3-1.20.3-0.3
Bone: final force0.10.10.9-0.2-0.2-0.40.1-0.1-0.3-0.4-0.3-0.2-0.20.21.0-0.10.2
Bone: final moment0.10.10.7-0.2-0.1-0.40.0-0.1-0.2-0.3-0.3-0.1-0.10.10.8-0.10.1
Food consumed during 24 hour testing period0.40.81.2-0.70.7-0.5-1.00.80.8-1.1-1.1-1.0-1.01.0-0.51.0-1.0
Glucose0.71.12.11.2-0.91.31.1-1.0-0.81.41.31.21.2-1.2-0.1-0.40.3
Heart weight0.10.20.5-0.50.6-0.1-0.40.50.5-0.2-0.10.00.00.0-0.6-0.70.7
Delay discount hyperbolic model param0.50.63.5-0.1-0.2-0.80.5-0.3-0.30.40.30.20.2-0.20.8-1.81.9
Intermittent access intake day 1-15 change0.10.31.90.3-0.6-0.20.4-0.7-0.90.10.00.10.1-0.21.40.5-0.5
Intermittent access intake escalation0.10.31.80.3-0.6-0.30.4-0.7-0.90.10.10.20.2-0.41.30.4-0.4
Intermittent access intake escalation 20.20.40.80.6-0.70.40.7-0.7-0.80.70.50.40.4-0.50.90.1-0.2
Intermitt. access day 1 inactive lever presses0.10.81.40.6-0.70.50.9-0.8-1.01.00.70.70.7-0.81.2-1.11.0
Intermitt. access day 15 inactive lever presses0.00.10.5-0.40.2-0.7-0.10.10.0-0.2-0.30.10.1-0.10.4-0.40.4
Intermitt. access escalation Index0.20.51.9-0.20.1-0.2-0.50.30.4-0.9-0.7-0.8-0.80.9-0.11.4-1.3
Intermittent access day 1 total infusions0.20.72.40.7-0.31.10.0-0.20.00.30.30.60.7-0.7-1.21.5-1.6
Intermittent access day 15 total infusions0.10.31.40.4-0.3-0.00.1-0.4-0.50.10.10.40.4-0.40.21.2-1.2
Intermittent access terminal intake (last 3 days)0.10.20.70.20.0-0.1-0.1-0.00.00.10.10.40.4-0.4-0.40.8-0.8
Intermittent access total infusions0.20.30.60.5-0.20.30.2-0.4-0.30.40.40.70.7-0.7-0.40.7-0.7
Intermittent access day 1 locomotion0.20.40.6-0.50.6-0.3-0.70.60.7-0.5-0.7-0.6-0.60.7-0.70.7-0.7
Intermittent access day 15 total locomotion0.41.42.0-1.31.2-1.4-1.31.11.1-1.3-1.3-1.3-1.31.2-0.50.8-0.8
Intermittent access total locomotion0.60.71.0-0.90.9-1.0-1.00.80.9-1.0-1.0-0.9-0.90.9-0.50.6-0.6
Intermittent access standard deviation0.20.91.71.1-1.20.51.1-1.3-1.31.30.90.80.8-0.91.10.1-0.1
Left kidney weight0.00.20.40.2-0.4-0.20.4-0.4-0.40.20.40.60.6-0.50.6-0.50.5
Right kidney weight0.10.93.1-1.20.7-1.8-0.60.60.3-1.1-0.9-0.9-0.90.91.1-0.80.9
Cocaine induced anxiety0.20.51.2-0.80.7-1.1-0.40.60.6-0.4-0.4-0.6-0.50.6-0.1-1.11.1
Post-drug Anxiety0.70.81.2-1.00.9-1.1-0.81.01.0-1.0-0.9-1.1-1.01.0-0.5-0.10.2
Baseline Anxiety0.50.83.70.00.10.4-0.60.30.5-0.8-0.6-0.5-0.50.5-0.81.9-1.9
Tail length0.52.66.32.2-1.82.51.7-1.7-1.51.81.51.61.6-1.60.30.7-0.8
Length with tail0.42.03.31.8-1.71.81.7-1.6-1.51.71.21.21.2-1.31.0-0.40.3
Length without tail0.00.21.0-0.20.1-0.40.10.10.10.2-0.10.10.1-0.10.0-1.01.0
Times rat made contact with spout1.31.53.01.6-1.31.71.3-1.3-1.11.61.41.31.3-1.30.00.1-0.2
Lifetime Intake0.10.20.50.3-0.00.0-0.0-0.2-0.20.20.20.50.6-0.5-0.40.7-0.7
Liver weight, left0.91.62.91.3-0.91.21.2-1.0-0.81.71.61.71.7-1.6-0.2-0.90.8
Liver weight, right1.22.13.61.8-1.41.91.6-1.3-1.11.71.71.81.8-1.7-0.2-0.30.2
Locomotor activity0.10.20.50.5-0.40.60.5-0.2-0.20.70.70.30.3-0.3-0.5-0.30.2
Locomotor testing distance0.51.11.81.3-1.31.11.4-1.2-1.21.31.10.90.9-0.90.7-0.50.4
Locomotor testing rearing0.41.33.31.2-1.50.81.5-1.5-1.71.10.70.50.6-0.61.8-0.50.5
Locomotion in novel chamber4.35.88.8-2.72.9-2.2-2.82.93.0-2.4-2.3-2.3-2.32.5-2.70.6-0.5
Locomotion in novel chamber post-restriction0.51.42.9-1.31.5-1.7-1.31.41.4-0.8-0.8-0.9-1.00.9-1.50.00.0
Fecal boli incidents, locomotor time 10.10.21.0-0.20.3-0.1-0.40.30.2-0.5-0.4-0.0-0.10.1-0.11.0-1.0
Change in fecal boli incidents, locomotor task0.30.31.20.2-0.4-0.00.4-0.7-0.90.40.3-0.1-0.10.01.1-0.80.8
Time >=10cm from walls, locomotor time 10.81.02.2-1.41.5-1.5-1.31.11.0-1.1-0.8-0.6-0.60.6-0.80.2-0.2
Bouts of movement, locomotor time 12.33.07.6-1.11.7-0.5-1.91.92.2-1.2-1.3-1.3-1.31.3-2.82.3-2.3
Total resting periods, locomotor time 12.73.27.0-1.31.8-0.7-2.01.92.2-1.4-1.4-1.3-1.41.3-2.62.3-2.3
Rest time, locomotor task time 10.50.82.80.9-0.61.30.2-0.4-0.20.40.60.70.7-0.7-0.61.6-1.7
Distance moved, locomotor task time 10.30.71.6-1.01.0-0.4-0.91.21.3-0.8-0.9-0.7-0.70.7-1.1-0.30.3
Vertical activity count, locomotor time 10.00.10.7-0.0-0.3-0.10.3-0.3-0.40.0-0.2-0.3-0.30.30.8-0.50.5
Time >=10cm from walls, locomotor time 20.10.30.70.3-0.40.40.3-0.5-0.60.00.50.90.8-0.80.50.3-0.3
Bouts of movement, locomotor time 20.82.73.6-1.41.5-1.3-1.81.81.9-1.6-1.7-1.5-1.41.4-1.91.8-1.7
Total resting periods, locomotor time 20.62.43.5-1.41.5-1.4-1.71.71.8-1.5-1.6-1.3-1.31.3-1.91.6-1.5
Rest time, locomotor task time 20.30.50.80.8-0.70.50.7-0.7-0.60.90.80.90.9-0.9-0.00.2-0.2
Distance moved, locomotor task time 20.81.01.9-1.11.2-0.6-1.21.31.4-1.2-1.0-0.7-0.70.7-1.30.7-0.6
Vertical activity count, locomotor time 20.40.91.7-0.70.4-0.7-0.80.40.3-1.3-1.1-1.2-1.21.20.41.3-1.3
Light reinforcement 11.04.67.4-2.72.7-2.5-2.32.72.5-1.9-1.8-2.1-2.12.1-1.7-1.21.3
Light reinforcement 20.61.43.5-1.31.5-0.9-1.01.61.6-0.8-0.5-0.4-0.40.4-1.9-1.31.4
Bone: marrow area0.10.20.40.4-0.40.20.4-0.4-0.50.40.60.60.6-0.60.5-0.10.1
Bone: maximum diameter0.20.50.90.6-0.50.50.7-0.4-0.40.80.90.90.9-0.90.2-0.70.7
Bone: maximum force0.00.10.7-0.2-0.1-0.40.0-0.1-0.3-0.4-0.1-0.0-0.00.00.8-0.10.1
Bone: maximum moment0.00.10.4-0.2-0.0-0.4-0.1-0.0-0.2-0.4-0.10.0-0.00.00.6-0.00.0
Mean time between licks in bursts0.42.36.2-1.81.9-1.7-1.21.71.5-0.5-0.4-0.7-0.80.8-1.3-2.42.5
Mean num. licks in bursts0.10.10.4-0.30.4-0.0-0.30.50.5-0.1-0.3-0.5-0.50.5-0.6-0.10.1
Cd content in liver2.42.74.52.0-2.12.11.5-2.0-1.90.91.01.31.4-1.31.31.7-1.7
Co content in liver0.91.03.81.1-1.11.30.5-1.0-0.90.1-0.1-0.2-0.10.10.61.9-1.9
Cu content in liver0.70.83.60.3-0.50.4-0.1-0.3-0.2-0.6-0.7-0.9-0.90.90.41.9-1.9
Fe content in liver3.54.35.92.1-2.21.72.4-2.2-2.22.32.22.32.3-2.31.6-1.51.4
K content in liver1.01.01.9-1.11.3-1.2-0.81.31.3-0.3-0.2-0.3-0.30.3-1.4-1.11.2
Mg content in liver0.10.10.6-0.40.4-0.6-0.10.30.2-0.00.0-0.1-0.10.1-0.2-0.80.8
Mn content in liver0.30.41.0-0.80.7-1.0-0.60.60.5-0.5-0.5-0.5-0.60.60.0-0.60.7
Na content in liver3.13.56.81.3-1.60.22.0-2.0-2.31.81.71.81.8-1.82.6-2.12.1
Rb content in liver5.76.79.2-2.42.5-2.0-2.82.62.7-2.8-3.0-3.0-3.03.0-2.11.9-1.9
Se content in liver0.10.10.6-0.40.5-0.2-0.40.50.5-0.3-0.1-0.1-0.10.1-0.8-0.10.1
Sr content in liver0.70.61.30.4-0.20.40.6-0.3-0.31.01.01.11.1-1.1-0.1-1.01.0
Zn content in liver0.00.00.10.1-0.10.10.00.00.1-0.0-0.2-0.3-0.30.3-0.20.2-0.2
Bone: minimum diameter0.10.20.6-0.60.5-0.8-0.50.50.5-0.6-0.4-0.3-0.30.3-0.0-0.00.1
Time in familiar zone, hab. session 10.80.92.11.3-0.91.40.9-0.8-0.61.11.21.01.0-1.0-0.40.5-0.5
Time in novel zone, hab. session 10.20.20.40.4-0.40.50.4-0.4-0.50.20.40.70.7-0.60.3-0.30.3
Total zone transitions, hab. session 10.81.22.5-1.30.8-1.6-0.90.80.6-1.6-1.4-1.3-1.31.30.6-0.30.4
Total locomotion distance, hab. session 11.52.13.6-1.61.5-1.5-1.61.61.6-1.9-1.8-1.5-1.51.6-0.80.6-0.6
Locomotion velocity, hab. session 11.31.82.9-1.61.4-1.7-1.51.51.4-1.7-1.6-1.4-1.41.4-0.5-0.10.1
Time in familiar zone, hab. session 20.50.51.20.7-0.50.60.8-0.5-0.51.01.10.80.8-0.80.0-0.90.8
Time in novel zone, hab. session 20.20.21.10.0-0.20.2-0.2-0.1-0.1-0.5-0.5-0.1-0.10.10.21.0-1.0
Total zone transitions, hab. session 20.30.40.9-0.70.7-0.6-0.70.60.6-0.6-0.8-0.9-0.91.0-0.10.0-0.0
Total locomotion distance, hab. session 21.62.13.0-1.31.5-0.8-1.61.61.7-1.4-1.6-1.6-1.61.6-1.41.0-1.0
Locomotion velocity, hab. session 21.62.13.0-1.41.6-1.1-1.61.61.6-1.4-1.6-1.7-1.71.7-1.10.7-0.6
Novel to familiar place preference ratio0.81.02.31.2-0.91.50.7-0.9-0.61.01.01.11.1-1.1-0.51.0-1.1
Novelty place preference0.91.12.41.3-1.01.60.8-0.9-0.70.91.11.21.2-1.2-0.41.1-1.1
Time in novel zone, NPP test1.31.63.31.5-1.21.81.0-1.1-0.91.21.31.51.5-1.5-0.31.0-1.1
Total zone transitions, NPP test1.42.13.8-1.41.2-1.2-1.51.31.2-1.7-1.8-2.0-2.02.0-0.20.8-0.7
Total locomotion distance, NPP test1.42.02.9-1.41.4-1.0-1.61.51.5-1.5-1.7-1.7-1.71.7-0.90.9-0.9
Locomotion velocity, NPP test2.02.94.1-1.81.8-1.6-1.91.81.8-1.8-2.0-2.0-2.02.0-1.00.5-0.4
Intraocular pressure1.22.02.9-1.51.7-1.4-1.61.61.6-1.2-1.4-1.7-1.61.5-1.10.4-0.3
Delta distance traveled before/after self-admin0.00.10.2-0.30.0-0.2-0.10.10.1-0.4-0.2-0.2-0.20.20.5-0.20.2
Delta ambulatory time before/after self-admin0.10.20.4-0.60.4-0.5-0.40.50.5-0.6-0.4-0.4-0.40.30.1-0.20.2
Parametrial fat weight0.10.10.60.10.0-0.20.2-0.1-0.00.60.40.20.3-0.2-0.0-0.80.8
Pavlov. Cond. lever latency0.40.52.4-0.50.9-0.2-0.50.91.00.20.2-0.1-0.10.1-1.6-0.70.7
Pavlov. Cond. magazine entry latency0.10.20.30.5-0.50.50.4-0.5-0.40.30.10.30.3-0.20.40.4-0.5
Pavlov. Cond. change in total contacts0.50.52.60.2-0.30.3-0.2-0.3-0.3-0.6-0.7-0.2-0.20.20.61.6-1.6
Pavlov. Cond. index score0.40.51.00.8-1.00.70.7-0.9-0.90.30.20.40.4-0.41.00.7-0.7
Pavlov. Cond. latency score0.40.61.50.8-1.00.70.7-1.0-1.00.20.10.30.3-0.31.20.8-0.8
Pavlov. Cond. lever contacts0.30.31.60.4-0.70.00.4-0.7-0.7-0.2-0.3-0.0-0.00.01.30.6-0.6
Pavlov. Cond. magazine entry number0.40.51.0-0.91.0-0.9-0.70.90.8-0.4-0.3-0.5-0.50.5-0.7-0.80.8
Pavlov. Cond. intertrial magazine entries0.20.20.6-0.20.30.1-0.40.40.5-0.3-0.3-0.2-0.20.2-0.70.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.80.6-0.70.60.4-0.6-0.50.1-0.00.20.2-0.20.60.9-0.9
Pavlov. Cond. response bias0.30.40.70.7-0.80.60.6-0.8-0.70.30.10.40.4-0.40.80.7-0.7
Pavlov. Cond. lever latency0.00.00.1-0.20.3-0.3-0.20.20.20.0-0.00.00.00.0-0.2-0.30.3
Pavlov. Cond. magazine entry latency0.20.20.7-0.40.0-0.4-0.20.10.0-0.5-0.5-0.8-0.80.80.8-0.10.1
Pavlov. Cond. change in total contacts0.20.51.10.8-1.00.80.7-1.0-1.00.30.30.40.4-0.41.00.8-0.8
Pavlov. Cond. index score0.00.10.30.2-0.40.30.3-0.3-0.30.00.1-0.1-0.10.10.50.1-0.1
Pavlov. Cond. latency score0.00.00.1-0.0-0.10.00.0-0.0-0.0-0.2-0.1-0.3-0.30.30.30.1-0.1
Pavlov. Cond. lever contacts0.20.30.50.7-0.70.70.6-0.6-0.60.40.50.40.4-0.40.50.2-0.2
Pavlov. Cond. magazine entry number0.10.10.7-0.00.20.1-0.10.20.20.10.20.40.4-0.4-0.9-0.0-0.0
Pavlov. Cond. intertrial magazine entries1.12.53.8-1.51.8-1.3-1.91.81.9-1.4-1.7-1.4-1.41.4-1.91.2-1.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.1-0.20.10.1-0.1-0.1-0.1-0.1-0.2-0.20.20.40.2-0.2
Pavlov. Cond. response bias0.30.41.40.6-0.90.40.8-0.8-0.90.40.30.20.2-0.21.2-0.30.3
Time in closed arm before self-admin0.81.42.41.6-1.41.51.2-1.5-1.41.11.31.11.1-1.00.50.8-0.9
Time in closed arm after self-admin0.20.20.60.6-0.70.60.5-0.5-0.40.00.30.20.3-0.2-0.00.7-0.8
Time in open arm before self-admin1.92.34.0-1.81.9-1.4-1.72.02.0-1.5-1.5-1.4-1.51.4-1.3-0.30.4
Time in open arm after self-admin0.40.41.80.2-0.40.00.5-0.7-0.80.40.30.40.5-0.51.3-0.70.7
Bone: periosteal estimation0.10.30.50.4-0.50.30.5-0.5-0.50.30.60.70.7-0.70.6-0.20.1
Bone: periosteal perimeter0.20.40.90.7-0.50.80.6-0.3-0.20.70.90.90.9-0.9-0.40.0-0.1
Bone: post-yield work0.10.10.5-0.30.1-0.7-0.20.1-0.0-0.5-0.3-0.5-0.50.50.5-0.00.0
Progressive ratio test 1 active lever presses0.51.01.3-0.91.0-1.0-1.10.91.0-1.0-1.0-0.9-0.90.9-0.91.0-1.0
Progressive ratio test 1 breakpoint0.50.81.1-0.80.9-0.9-1.10.81.0-0.8-0.9-0.8-0.70.8-0.91.0-1.0
Progressive ratio test 1 inactive lever presses0.10.30.8-0.70.4-0.9-0.50.30.1-0.8-0.7-0.7-0.60.60.5-0.20.2
Progressive ratio test 2 active lever presses1.11.62.6-1.41.3-1.5-1.51.21.0-1.6-1.5-1.4-1.31.3-0.40.8-0.8
Progressive ratio test 2 breakpoint1.31.72.7-1.41.3-1.5-1.51.31.1-1.6-1.5-1.4-1.31.3-0.50.9-0.9
Progressive ratio test 2 inactive lever presses0.30.81.9-1.10.8-1.4-0.90.90.7-1.3-1.2-0.9-0.80.8-0.00.2-0.2
Incentive Sensitization - Responses0.10.20.7-0.50.3-0.6-0.40.2-0.2-0.7-0.4-0.4-0.40.40.9-0.10.2
Incentive Sensitization - Breakpoint0.10.30.8-0.70.4-0.8-0.50.4-0.0-0.9-0.6-0.6-0.60.50.8-0.10.1
Sum of active levers in priming session hrs 5-62.32.23.91.3-0.91.81.3-0.9-0.81.81.91.92.0-1.9-0.2-1.41.3
Progressive ratio0.30.91.5-0.60.9-0.2-1.00.70.6-0.6-0.9-1.2-1.21.1-0.91.2-1.2
Food seeking constrained by brief footshock0.60.71.7-0.91.0-0.1-1.01.31.3-0.7-0.7-0.6-0.60.6-1.10.2-0.1
Seeking ratio, punishment vs. effort0.10.31.2-0.20.0-0.00.20.30.30.10.30.60.6-0.5-0.0-1.11.1
Retroperitoneal fat weight0.31.41.9-1.41.3-1.4-1.41.31.3-1.1-1.4-1.2-1.21.3-0.50.4-0.3
Reaction time number correct0.31.12.2-1.11.0-1.0-1.30.90.8-1.5-1.2-1.0-1.01.1-0.50.9-0.9
Reaction time mean minus median0.31.62.61.3-1.11.11.4-1.3-1.11.61.61.41.4-1.40.7-1.11.1
Reaction time mean minus median AUC0.10.81.31.0-0.91.01.0-1.0-0.81.21.10.80.8-0.80.7-0.60.6
Reaction time num false alarms1.11.83.0-1.51.6-1.4-1.61.71.7-1.2-1.3-1.2-1.21.2-1.50.5-0.5
Reaction time num false alarms AUC0.92.03.2-1.71.8-1.7-1.61.81.8-1.2-1.3-1.2-1.21.2-1.40.1-0.0
Reaction time trials correct on left0.31.12.2-1.11.0-1.0-1.30.90.8-1.5-1.2-1.0-1.01.1-0.50.9-0.9
Reaction time trials on left0.31.02.0-1.01.0-1.0-1.20.90.8-1.4-1.2-1.0-1.01.0-0.50.9-0.8
Reaction time mean1.22.64.12.0-1.92.01.9-1.9-1.72.01.81.31.4-1.41.1-0.40.3
Reaction time mean AUC0.82.03.41.8-1.71.81.7-1.7-1.51.81.61.11.1-1.11.0-0.20.1
Median of all reaction times1.52.44.42.1-1.92.11.8-1.9-1.71.91.71.11.1-1.21.00.1-0.2
Reaction time omissions0.61.01.70.8-0.80.51.1-1.0-1.01.21.00.70.7-0.61.1-1.31.3
Reaction time false alarm rate0.50.81.6-1.01.1-1.1-0.91.21.2-0.4-0.6-0.6-0.60.6-1.1-0.40.5
Reaction time premature initiation rate0.00.10.20.1-0.10.40.00.0-0.0-0.10.10.20.2-0.3-0.40.4-0.4
Reaction time premature initiations0.10.20.6-0.30.20.1-0.40.30.2-0.7-0.4-0.2-0.20.1-0.50.8-0.8
Std. dev. reaction times0.82.74.31.7-1.61.41.9-1.8-1.62.12.01.71.7-1.81.1-1.31.3
Reaction time trials completed0.31.02.0-1.01.0-1.0-1.20.90.8-1.4-1.2-1.0-1.01.0-0.50.9-0.8
Reaction time trials AUC0.20.81.7-1.00.9-0.9-1.10.80.7-1.3-1.1-0.9-0.90.9-0.40.8-0.8
Run reversals in cocaine runway, females0.40.50.8-0.50.6-0.7-0.60.70.8-0.5-0.5-0.6-0.60.6-0.90.8-0.8
Run reversals in cocaine runway, males1.31.45.5-1.01.2-0.3-1.21.71.9-1.0-0.9-0.7-0.70.8-2.40.5-0.5
Latency to leave start box in cocaine runway1.42.04.4-1.61.3-2.1-1.41.31.0-1.7-1.7-1.7-1.71.5-0.40.2-0.1
Latency to leave start box in cocaine runway, F0.40.52.0-0.90.6-1.4-0.50.60.3-0.7-0.7-0.6-0.60.4-0.0-0.80.9
Latency to leave start box in cocaine runway, M4.24.06.1-2.01.8-2.2-2.11.71.6-2.3-2.4-2.5-2.52.5-0.71.5-1.4
Std. dev. time between licks in bursts0.20.31.0-0.40.7-0.4-0.30.50.40.10.30.10.1-0.1-0.7-1.01.0
Total sessions with >9 infusions0.30.40.8-0.80.9-0.8-0.90.80.7-0.6-0.7-0.3-0.20.3-0.70.6-0.6
Short access day 1 total inactive lever presses0.40.71.9-1.11.1-1.4-0.91.11.0-0.8-0.7-0.6-0.50.7-0.6-0.10.2
Short access day 10 total inactive lever presses0.00.10.40.1-0.20.20.3-0.00.00.20.10.20.2-0.2-0.1-0.60.6
Short access day 1 total infusions0.71.32.7-1.51.6-1.6-1.41.51.3-1.1-1.1-0.7-0.70.8-1.10.2-0.2
Short access day 10 total infusions0.60.94.20.20.30.5-0.60.40.6-0.3-0.30.30.4-0.3-1.82.0-2.0
Short access total infusions0.40.51.9-0.40.6-0.3-0.80.50.5-0.6-0.6-0.1-0.00.1-1.01.4-1.4
Short access day 1 locomotion1.01.62.6-1.51.5-1.6-1.51.41.3-1.5-1.4-1.0-1.01.1-1.10.4-0.3
Short access day 10 total locomotion0.00.20.3-0.30.3-0.2-0.40.30.5-0.1-0.5-0.4-0.60.5-0.30.4-0.4
Short access total locomotion1.52.33.5-1.61.5-1.4-1.71.51.6-1.7-1.9-1.6-1.71.7-1.01.0-0.9
One hour access (0.3 mA shock)0.81.02.01.2-0.81.40.6-0.8-0.60.90.71.11.1-1.1-0.51.2-1.2
Compulsive drug intake0.10.21.3-0.30.3-0.1-0.10.30.2-0.1-0.0-0.1-0.10.1-0.2-1.11.1
One hour access (shock baseline)0.20.61.61.0-0.60.90.5-0.7-0.50.80.70.80.8-0.7-0.31.2-1.3
Social response proportion0.20.20.50.6-0.40.50.5-0.6-0.50.50.70.40.4-0.50.1-0.0-0.0
Social responses0.50.72.21.0-0.91.50.9-0.8-0.80.80.80.60.6-0.70.4-0.50.4
Social time2.23.46.42.3-2.52.12.2-2.2-2.21.51.71.81.8-1.91.50.3-0.4
Soleus weight0.82.54.9-2.02.1-2.2-1.71.81.6-1.2-1.4-1.4-1.41.3-1.1-1.01.1
Bone: stiffness0.30.61.8-0.80.3-1.4-0.40.2-0.0-0.9-0.9-0.9-0.90.81.3-0.20.3
Tibialis anterior weight2.79.416.3-3.84.0-3.5-3.63.83.7-2.9-2.7-2.7-2.72.7-3.0-0.20.4
Time to tail flick, vehicle, before self-admin1.21.52.71.3-1.21.31.3-1.3-1.21.71.61.31.2-1.10.9-0.60.5
Time to tail flick, vehicle, after self-admin0.30.61.31.0-1.11.00.9-1.1-1.00.40.60.50.5-0.50.90.6-0.7
Time to tail flick, test, before self-admin2.83.24.8-2.02.2-1.6-2.22.12.1-1.8-1.6-1.7-1.71.8-2.00.9-0.8
Time to tail flick, test, after self-admin0.40.41.1-0.60.6-0.7-0.80.50.5-0.8-0.7-0.4-0.40.5-0.41.0-1.0
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.0-0.1-0.3-0.1-0.0-0.1-0.5-0.3-0.2-0.30.20.10.6-0.6
Delta time to tail flick, test, before/after SA1.01.22.21.3-1.50.91.2-1.5-1.50.80.71.01.1-1.21.40.4-0.4
Tibia length0.61.64.51.1-1.40.61.5-1.5-1.61.20.91.11.1-1.02.1-1.11.1
Ambulatory time before self-admin0.61.72.81.3-1.40.81.5-1.6-1.71.41.21.31.3-1.41.3-0.90.9
Ambulatory time after self-admin0.60.92.80.4-0.80.21.0-0.9-1.10.60.50.70.7-0.81.7-1.41.4
Bone: tissue strength0.20.20.5-0.20.1-0.2-0.30.10.1-0.5-0.6-0.4-0.40.40.20.7-0.7
Total heroin consumption0.91.14.21.2-0.62.10.7-0.4-0.11.31.11.31.2-1.0-1.10.2-0.2
Bone: trabecular number2.14.07.32.3-2.71.92.5-2.5-2.51.81.71.91.9-1.92.1-0.40.3
Bone: trabecular spacing2.33.44.7-2.01.9-1.9-2.11.91.8-2.0-2.1-2.2-2.22.2-0.71.0-1.0
Bone: trabecular thickness4.35.99.12.9-3.02.72.8-2.9-2.82.22.42.52.5-2.52.0-0.1-0.0
Bone: trabecular tissue density0.30.51.3-0.90.6-1.1-0.50.60.4-0.7-0.7-0.9-0.90.90.6-0.60.7
Water consumed over 24 hours0.20.42.50.2-0.30.3-0.2-0.2-0.2-0.4-0.5-0.3-0.30.30.21.6-1.6
Number of responses in last shaping day0.20.20.50.3-0.20.40.4-0.2-0.30.60.50.70.7-0.50.1-0.50.5