Hub : Genes

LOC120094677

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XR_005489123.1 0.03 0.02 4.3e-03 0.03 0.02 0.02 0.02 8.6e-04 2.6e-03 3.4e-03 4.3e-03
2 Brain isoform ratio XR_005489124.1 0.03 0.02 3.8e-03 0.03 0.03 0.02 0.02 7.3e-04 2.0e-03 3.7e-03 2.9e-03
3 PL isoform ratio XR_005489123.1 0.04 0.03 7.0e-04 0.02 0.03 0.03 0.03 1.5e-03 6.2e-04 1.6e-04 5.4e-04
4 PL isoform ratio XR_005489124.1 0.04 0.03 7.7e-04 0.02 0.03 0.03 0.03 1.7e-03 7.7e-04 1.7e-04 7.4e-04
5 NAcc isoform ratio XR_005489123.1 0.03 0.02 5.6e-03 0.02 0.02 0.02 0.01 4.8e-03 1.9e-03 2.5e-03 8.3e-03
6 NAcc isoform ratio XR_005489124.1 0.03 0.02 3.8e-03 0.02 0.02 0.02 0.02 3.6e-03 1.2e-03 1.7e-03 5.5e-03
7 Brain mRNA stability LOC120094677 0.06 0.04 8.7e-06 0.06 0.04 0.03 0.04 6.8e-06 1.1e-04 4.5e-04 6.9e-05
8 PL intron excision ratio chr9_44601496_44602201 0.08 0.04 1.4e-09 0.1 0.07 0.07 0.08 9.0e-11 4.5e-08 2.5e-08 7.9e-09
9 NAcc gene expression LOC120094677 0.04 0.02 6.3e-04 0.02 0.03 0.02 0.02 7.7e-04 6.0e-04 8.6e-04 1.8e-03
10 PL gene expression LOC120094677 0.05 0.03 4.2e-05 0.02 0.04 0.04 0.03 3.5e-03 1.3e-05 3.9e-05 1.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.52.55.7-1.91.9-1.11.11.8-1.7-1.9-2.4-0.10.0
Area under the delay curve2.12.24.8-0.90.9-1.71.71.4-1.5-0.90.0-2.2-2.2
BMI with tail1.03.35.32.2-2.21.8-1.8-1.81.72.32.30.30.3
BMI without tail0.00.00.1-0.10.1-0.30.30.2-0.2-0.2-0.0-0.1-0.1
Body weight0.20.71.41.1-1.10.5-0.6-0.70.71.01.20.40.5
Weight adjusted by age3.43.95.72.3-2.32.4-2.4-1.91.82.21.61.21.3
Bone surface0.30.52.3-0.70.70.2-0.20.4-0.4-0.6-1.50.50.5
Bone volume0.81.34.7-1.41.4-0.30.41.1-1.1-1.4-2.20.20.3
Breakpoint value in progressive ratio session0.10.10.4-0.50.5-0.30.30.3-0.2-0.6-0.1-0.2-0.3
Number of licking bursts0.91.01.4-1.11.1-1.01.01.0-1.0-1.2-1.1-0.7-0.8
Context. condit. distance diff. score0.60.71.3-0.80.8-0.90.91.1-1.1-0.6-0.3-0.7-0.4
Locomotion velocity, session 10.50.51.2-0.10.1-0.90.80.7-0.8-0.20.6-1.1-1.0
Locomotion distance, session 11.41.85.41.8-1.80.5-0.5-1.11.11.82.30.00.2
Locomotion velocity, session 22.32.64.52.1-2.11.4-1.4-1.71.62.02.00.40.4
Locomotion distance, session 21.31.93.01.7-1.70.9-1.0-1.61.51.61.70.40.4
Locomotion velocity, session 30.10.10.30.2-0.20.5-0.5-0.20.20.30.50.20.3
Locomotion distance, session 30.00.00.1-0.10.10.3-0.3-0.10.2-0.0-0.10.30.3
Stereotopy head waving bouts, day 30.40.40.7-0.70.7-0.40.40.7-0.7-0.8-0.7-0.5-0.5
Stereotopy head waving duration, day 30.50.60.9-0.60.6-0.80.80.8-0.9-0.7-0.2-0.9-0.9
Locomotion velocity, session 72.12.34.11.9-1.91.3-1.3-1.41.42.01.80.70.9
Locomotion distance, session 70.40.51.41.0-1.00.3-0.3-0.60.61.20.9-0.10.0
Stereotopy head waving bouts, day 70.20.20.6-0.10.10.1-0.10.4-0.5-0.30.5-0.8-0.7
Stereotopy head waving duration, day 70.20.21.10.5-0.50.3-0.4-0.00.00.31.0-0.20.0
Locomotion velocity, session 80.80.91.51.2-1.21.0-1.0-0.60.61.21.20.40.7
Locomotion distance, session 80.71.12.21.3-1.30.7-0.7-0.90.81.41.50.40.7
Degree of sensitization distance0.50.51.00.7-0.7-0.50.50.1-0.10.70.9-1.0-0.9
Degree of sensitization stereotypy0.10.10.40.3-0.30.5-0.50.0-0.10.20.7-0.2-0.1
Conditioned locomotion1.11.31.9-1.31.3-1.01.01.3-1.3-1.4-1.0-0.9-0.9
Cocaine response after cond. corrected0.40.40.9-0.30.3-0.80.80.6-0.6-0.4-0.2-0.9-0.9
Cocaine response after cond. not corrected0.20.20.50.1-0.1-0.50.50.3-0.30.00.2-0.7-0.7
Cocaine response before conditioning1.01.21.91.4-1.41.1-1.1-0.90.91.41.30.50.6
Saline control response0.40.51.01.0-1.00.5-0.5-0.60.60.90.90.50.6
Bone: connectivity density0.61.02.8-1.21.2-0.60.61.1-1.0-1.2-1.7-0.2-0.1
Bone: cortical apparent density5.67.310.03.2-3.22.6-2.6-2.92.93.22.51.81.9
Bone: cortical area0.20.30.90.5-0.51.0-1.0-0.40.40.5-0.10.30.3
Bone: cortical porosity0.40.51.4-0.90.9-0.30.30.6-0.6-0.9-1.20.10.1
Bone: cortical porosity0.40.40.9-0.80.8-0.50.50.7-0.7-0.8-0.90.10.2
Bone: cortical thickness0.20.30.70.6-0.60.8-0.8-0.30.30.60.10.20.3
Bone: cortical thickness0.00.00.10.3-0.3-0.00.00.3-0.30.10.0-0.3-0.2
Bone: cortical tissue density5.67.310.03.2-3.22.6-2.5-2.92.93.12.51.91.9
Condit. Reinf. active minus inactive responses3.33.79.8-0.60.6-2.22.21.9-2.0-0.60.9-3.1-2.9
Condit. Reinf. active-inactive response ratio4.85.212.0-0.90.9-2.82.82.3-2.4-0.81.1-3.5-3.2
Condit. Reinf. active responses1.31.65.2-0.10.1-1.11.11.2-1.3-0.10.9-2.3-2.1
Condit. Reinf. inactive responses0.70.91.81.1-1.11.3-1.3-0.90.80.90.70.20.3
Incentive salience index mean1.61.94.8-0.50.5-1.51.51.5-1.5-0.40.6-2.2-2.0
Condit. Reinf. lever presses0.00.00.1-0.10.1-0.10.10.4-0.40.00.0-0.10.1
Condit. Reinf. active minus inactive responses2.32.85.4-1.21.2-1.71.71.9-1.9-1.10.0-2.3-2.2
Condit. Reinf. active-inactive response ratio3.13.24.5-1.71.7-1.91.92.1-2.1-1.6-0.9-1.9-1.9
Condit. Reinf. active responses0.81.12.9-0.50.5-0.90.91.1-1.1-0.40.4-1.7-1.7
Condit. Reinf. inactive responses1.01.21.81.3-1.31.0-1.0-1.21.21.31.20.60.6
Condit. Reinf. lever presses0.40.51.1-0.50.5-0.40.40.9-0.9-0.5-0.0-1.1-1.0
Condit. Reinf. lever reinforcers received0.91.23.6-0.40.4-1.01.01.1-1.1-0.30.5-1.9-1.8
Conditioned reinforcement - actives1.21.22.5-0.60.6-1.41.41.1-1.1-0.70.0-1.6-1.6
Conditioned reinforcement - inactives0.20.20.40.3-0.3-0.60.60.1-0.10.30.5-0.5-0.5
Conditioned locomotion0.30.31.60.5-0.50.2-0.2-0.30.20.71.3-0.5-0.5
Patch foraging indifference point 0 sec1.62.63.81.2-1.22.0-1.9-1.71.81.60.51.81.7
Patch foraging indifference point AUC0.10.10.20.2-0.20.1-0.1-0.30.20.40.3-0.3-0.5
Delay disc. indifference point, 0s delay0.80.81.81.2-1.20.4-0.4-0.80.81.21.40.30.5
Delay disc. indifference point, 16s delay4.54.66.6-1.81.8-2.62.62.3-2.3-1.8-0.8-2.4-2.4
Delay disc. indifference point, 2s delay0.20.21.0-0.30.3-0.20.20.4-0.4-0.20.1-0.9-1.0
Delay disc. indifference point, 24s delay0.90.92.0-0.50.5-1.41.40.9-1.0-0.50.3-1.2-1.1
Delay disc. indifference point, 4s delay0.20.20.60.4-0.4-0.50.40.1-0.20.40.8-0.7-0.7
Delay disc. indifference point, 8s delay1.01.02.3-0.60.6-1.01.01.0-1.1-0.7-0.2-1.5-1.5
Indifference point function ln k0.30.50.60.6-0.60.7-0.7-0.80.80.80.60.70.6
Indifference point function log k0.30.50.60.6-0.60.7-0.7-0.80.80.80.60.70.6
Patch foraging total patch changes 0 sec1.21.93.01.0-1.01.7-1.7-1.61.61.40.31.51.4
Patch foraging total patch changes 12 sec1.11.42.21.0-1.01.5-1.4-1.21.21.20.41.31.4
Patch foraging total patch changes 18 sec0.30.40.80.1-0.10.9-0.9-0.80.80.80.10.40.1
Patch foraging total patch changes 24 sec1.41.72.51.0-1.01.6-1.5-1.51.51.40.31.41.4
Patch foraging total patch changes 6 sec0.60.91.90.6-0.61.4-1.3-1.01.01.0-0.11.00.9
Patch foraging time to switch 0 sec0.20.31.10.0-0.00.5-0.5-0.30.3-0.0-0.51.01.0
Patch foraging water rate 0 sec0.40.62.2-0.40.4-0.60.70.7-0.7-0.30.0-1.4-1.5
Patch foraging water rate 12 sec0.10.10.5-0.50.5-0.10.10.2-0.2-0.4-0.7-0.3-0.4
Patch foraging water rate 18 sec0.10.10.20.3-0.30.5-0.5-0.40.40.0-0.50.20.2
Patch foraging water rate 24 sec0.00.00.10.0-0.0-0.30.3-0.10.00.10.4-0.1-0.2
Patch foraging water rate 6 sec0.10.10.3-0.40.40.0-0.0-0.10.1-0.4-0.5-0.0-0.2
Seeking ratio, delayed vs. immediate footshock0.50.61.1-0.60.6-1.01.00.9-0.9-0.6-0.3-0.6-0.5
Distance traveled before self-admin0.20.20.8-0.20.2-0.10.00.1-0.1-0.5-0.90.70.7
Distance traveled after self-admin0.60.72.6-0.20.20.5-0.4-0.30.3-0.1-0.91.51.6
Extensor digitorum longus weight5.220.528.55.3-5.34.2-4.3-5.25.15.34.52.52.3
Bone: elastic displacement0.91.03.2-1.31.3-0.30.30.8-0.7-1.2-1.8-0.2-0.4
Bone: elastic work0.60.82.0-1.11.1-0.50.51.0-1.0-1.0-1.4-0.4-0.4
Bone: endosteal estimation0.10.10.5-0.50.5-0.10.10.3-0.3-0.5-0.70.0-0.0
Bone: endosteal perimeter0.00.10.2-0.40.40.2-0.20.3-0.3-0.4-0.4-0.1-0.2
Epididymis fat weight0.20.40.50.6-0.60.7-0.7-0.70.70.70.50.50.4
Delta time in closed arm before/after self-admin0.70.72.40.5-0.51.5-1.5-0.70.70.4-0.20.60.5
Delta time in open arm before/after self-admin1.61.52.4-1.61.6-1.41.31.4-1.3-1.1-1.3-0.5-0.5
Diff in mean of infusions in LGA sessions0.70.71.5-1.21.2-0.50.50.8-0.8-1.2-1.0-0.2-0.3
Delay discount exponential model param2.32.44.91.0-1.01.8-1.8-1.51.61.10.12.22.2
Extinction: sum of active levers before priming1.81.83.0-1.71.7-1.31.31.3-1.3-1.6-1.6-0.4-0.5
Active lever presses in extinction session 60.70.71.9-0.50.5-1.01.00.5-0.5-0.50.3-1.2-1.4
Bone: final force0.30.50.70.8-0.80.7-0.7-0.60.60.80.50.50.7
Bone: final moment0.30.50.70.8-0.80.8-0.8-0.60.60.80.40.50.7
Food consumed during 24 hour testing period0.30.31.10.7-0.70.1-0.2-0.20.10.61.1-0.5-0.5
Glucose0.50.71.4-1.21.2-0.50.60.7-0.6-1.1-1.1-0.2-0.3
Heart weight0.30.50.70.8-0.80.8-0.8-0.80.70.70.60.30.2
Delay discount hyperbolic model param1.61.74.00.7-0.71.5-1.5-1.21.30.7-0.22.02.0
Intermittent access intake day 1-15 change0.00.00.00.0-0.0-0.10.10.0-0.00.20.00.10.1
Intermittent access intake escalation0.40.30.8-0.40.4-0.90.90.7-0.7-0.2-0.0-0.6-0.4
Intermittent access intake escalation 20.50.51.1-0.60.6-1.01.00.8-0.9-0.30.1-0.8-0.7
Intermitt. access day 1 inactive lever presses0.20.20.80.1-0.1-0.00.0-0.20.3-0.1-0.70.90.9
Intermitt. access day 15 inactive lever presses0.30.40.80.3-0.30.9-0.9-0.50.50.5-0.40.70.7
Intermitt. access escalation Index0.20.20.7-0.10.1-0.0-0.00.4-0.40.10.7-0.8-0.7
Intermittent access day 1 total infusions1.31.43.1-1.01.0-1.31.31.1-1.1-1.0-0.4-1.6-1.8
Intermittent access day 15 total infusions1.21.32.1-1.01.0-1.51.41.1-1.1-0.8-0.4-1.3-1.4
Intermittent access terminal intake (last 3 days)0.50.51.4-0.50.5-0.80.80.6-0.6-0.4-0.1-1.1-1.2
Intermittent access total infusions1.01.21.9-1.01.0-1.31.20.9-1.0-0.9-0.5-1.3-1.4
Intermittent access day 1 locomotion0.00.00.10.0-0.0-0.00.00.0-0.1-0.00.2-0.2-0.2
Intermittent access day 15 total locomotion0.10.10.30.1-0.1-0.30.30.1-0.10.20.5-0.5-0.5
Intermittent access total locomotion0.10.10.30.2-0.2-0.20.20.0-0.00.20.6-0.4-0.4
Intermittent access standard deviation1.81.92.9-1.61.6-1.71.71.3-1.3-1.4-1.3-0.7-0.8
Left kidney weight1.02.74.91.5-1.52.2-2.2-1.71.71.20.61.61.6
Right kidney weight2.15.98.12.4-2.42.7-2.7-2.52.52.21.12.72.8
Cocaine induced anxiety4.95.76.92.6-2.62.5-2.5-2.62.62.62.41.61.6
Post-drug Anxiety1.31.54.31.4-1.41.1-1.1-1.11.01.42.1-0.4-0.3
Baseline Anxiety4.24.45.6-2.02.0-2.12.22.3-2.3-2.0-1.2-2.3-2.4
Tail length0.72.24.1-1.41.4-2.02.01.6-1.6-1.6-1.1-0.8-0.7
Length with tail0.00.10.3-0.10.1-0.50.50.2-0.2-0.3-0.20.30.4
Length without tail1.73.64.62.1-2.12.0-2.0-2.02.02.11.71.41.4
Times rat made contact with spout2.22.63.8-1.91.9-1.51.51.6-1.6-1.9-1.3-1.2-1.3
Lifetime Intake1.01.12.1-0.80.8-1.31.30.9-0.9-0.8-0.4-1.3-1.4
Liver weight, left0.30.41.30.0-0.00.7-0.7-0.50.5-0.0-0.81.11.1
Liver weight, right0.10.10.3-0.40.4-0.20.20.4-0.4-0.6-0.5-0.1-0.2
Locomotor activity0.10.10.3-0.50.5-0.00.00.3-0.2-0.4-0.2-0.1-0.2
Locomotor testing distance0.40.71.4-1.21.2-0.50.50.9-0.8-1.1-1.1-0.1-0.1
Locomotor testing rearing0.40.71.2-1.11.1-1.00.90.9-0.8-0.9-0.60.10.2
Locomotion in novel chamber3.44.17.22.4-2.42.1-2.1-2.12.12.32.70.40.3
Locomotion in novel chamber post-restriction0.70.91.31.0-1.00.9-1.0-1.21.11.11.00.40.2
Fecal boli incidents, locomotor time 10.20.20.6-0.10.1-0.60.60.3-0.40.10.2-0.8-0.8
Change in fecal boli incidents, locomotor task0.10.10.2-0.10.1-0.10.10.0-0.0-0.3-0.10.40.5
Time >=10cm from walls, locomotor time 11.21.21.61.3-1.31.2-1.3-1.21.21.20.70.50.4
Bouts of movement, locomotor time 11.41.66.3-0.20.2-0.90.90.5-0.60.01.3-2.3-2.5
Total resting periods, locomotor time 11.21.35.4-0.00.0-0.60.60.4-0.50.31.3-2.2-2.3
Rest time, locomotor task time 12.73.05.3-1.51.5-1.71.71.8-1.9-1.4-0.7-2.2-2.3
Distance moved, locomotor task time 11.41.62.61.3-1.31.6-1.6-1.31.31.21.00.80.8
Vertical activity count, locomotor time 10.30.30.80.5-0.50.5-0.5-0.50.50.40.50.80.9
Time >=10cm from walls, locomotor time 20.20.20.7-0.40.4-0.10.10.4-0.4-0.5-0.8-0.3-0.3
Bouts of movement, locomotor time 20.60.62.00.4-0.4-0.10.10.1-0.10.61.3-1.4-1.4
Total resting periods, locomotor time 20.50.51.40.5-0.50.1-0.1-0.10.00.61.2-1.2-1.2
Rest time, locomotor task time 20.70.81.4-1.11.1-0.70.70.9-0.9-1.2-1.0-0.6-0.7
Distance moved, locomotor task time 20.50.60.90.9-0.90.9-0.9-0.70.60.90.8-0.2-0.2
Vertical activity count, locomotor time 20.30.31.60.6-0.6-0.20.20.0-0.10.61.3-0.7-0.5
Light reinforcement 13.76.79.02.9-2.92.6-2.6-3.03.02.62.22.01.9
Light reinforcement 21.92.64.61.5-1.52.1-2.1-1.81.81.20.51.41.2
Bone: marrow area0.10.10.4-0.40.4-0.10.10.3-0.3-0.4-0.6-0.0-0.0
Bone: maximum diameter0.10.20.7-0.30.30.6-0.6-0.00.1-0.3-0.90.50.4
Bone: maximum force0.20.30.40.6-0.60.6-0.6-0.40.40.60.10.40.5
Bone: maximum moment0.20.30.50.6-0.60.7-0.7-0.40.40.60.10.40.5
Mean time between licks in bursts4.86.710.22.2-2.23.2-3.2-2.92.92.10.82.82.6
Mean num. licks in bursts0.10.10.30.3-0.30.4-0.4-0.30.30.30.60.10.0
Cd content in liver0.00.00.10.1-0.1-0.10.10.1-0.10.10.10.10.2
Co content in liver0.91.12.0-0.50.5-1.41.41.2-1.2-0.50.5-1.4-1.2
Cu content in liver1.72.13.7-0.80.8-1.91.91.6-1.7-0.70.6-1.9-1.6
Fe content in liver1.31.52.5-1.51.5-1.21.21.3-1.2-1.5-1.60.10.2
K content in liver1.61.62.70.9-0.91.7-1.6-1.41.40.90.21.41.2
Mg content in liver0.80.81.40.6-0.61.1-1.1-0.91.00.5-0.11.21.1
Mn content in liver0.60.71.10.9-0.90.7-0.7-1.01.00.90.60.90.8
Na content in liver0.60.72.4-0.30.30.4-0.4-0.20.2-0.2-1.21.51.5
Rb content in liver0.81.04.01.1-1.10.1-0.1-0.60.51.12.0-0.8-0.8
Se content in liver0.10.10.20.4-0.40.3-0.3-0.30.30.30.30.00.1
Sr content in liver0.10.10.4-0.40.4-0.10.1-0.10.1-0.4-0.60.20.1
Zn content in liver0.10.10.50.4-0.40.1-0.1-0.10.10.40.7-0.3-0.3
Bone: minimum diameter0.30.61.30.8-0.81.1-1.1-0.70.70.80.30.60.6
Time in familiar zone, hab. session 12.22.02.6-1.61.6-1.41.41.5-1.5-1.6-0.8-1.3-1.4
Time in novel zone, hab. session 10.10.10.5-0.20.2-0.10.10.1-0.1-0.3-0.70.10.1
Total zone transitions, hab. session 11.62.23.11.8-1.81.4-1.4-1.41.41.51.21.31.5
Total locomotion distance, hab. session 11.11.52.71.7-1.71.1-1.1-1.11.11.51.50.20.3
Locomotion velocity, hab. session 11.62.33.41.9-1.91.5-1.5-1.61.51.71.40.91.0
Time in familiar zone, hab. session 20.20.20.6-0.70.70.1-0.10.2-0.2-0.7-0.80.30.2
Time in novel zone, hab. session 20.30.30.6-0.00.0-0.70.70.5-0.6-0.10.2-0.8-0.7
Total zone transitions, hab. session 20.20.30.70.6-0.60.0-0.0-0.60.60.50.90.20.2
Total locomotion distance, hab. session 20.50.62.50.9-0.9-0.10.1-0.60.50.81.6-0.6-0.7
Locomotion velocity, hab. session 20.60.82.81.2-1.20.1-0.2-0.90.81.01.7-0.2-0.2
Novel to familiar place preference ratio2.52.63.2-1.61.6-1.61.61.7-1.7-1.6-1.2-1.7-1.8
Novelty place preference2.72.73.3-1.61.6-1.61.61.8-1.8-1.6-1.2-1.7-1.8
Time in novel zone, NPP test3.23.33.9-1.91.9-1.71.72.0-2.0-1.9-1.4-1.8-1.9
Total zone transitions, NPP test0.81.13.91.4-1.40.3-0.3-0.90.91.32.00.00.1
Total locomotion distance, NPP test0.60.82.91.2-1.20.2-0.2-0.70.71.01.7-0.4-0.3
Locomotion velocity, NPP test1.31.84.31.8-1.80.8-0.8-1.41.31.62.10.20.3
Intraocular pressure0.40.62.00.9-0.90.2-0.2-0.80.81.11.4-0.0-0.1
Delta distance traveled before/after self-admin0.60.71.10.5-0.51.0-1.0-0.80.80.80.21.01.0
Delta ambulatory time before/after self-admin0.70.71.20.5-0.51.1-1.0-0.90.90.90.21.01.0
Parametrial fat weight0.00.10.3-0.00.00.0-0.0-0.20.3-0.1-0.10.60.5
Pavlov. Cond. lever latency0.10.10.40.0-0.00.4-0.4-0.60.60.0-0.10.40.2
Pavlov. Cond. magazine entry latency0.10.20.3-0.40.4-0.50.50.5-0.5-0.3-0.0-0.5-0.4
Pavlov. Cond. change in total contacts0.70.71.7-0.40.4-1.01.01.0-1.0-0.30.0-1.3-1.2
Pavlov. Cond. index score0.50.71.1-0.80.8-0.90.91.0-1.0-0.7-0.4-0.8-0.7
Pavlov. Cond. latency score0.50.61.1-0.70.7-0.90.91.0-1.0-0.6-0.3-0.8-0.6
Pavlov. Cond. lever contacts0.10.10.3-0.20.2-0.30.30.5-0.5-0.1-0.2-0.3-0.1
Pavlov. Cond. magazine entry number1.21.52.11.3-1.31.3-1.3-1.41.41.10.71.21.1
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.00.0-0.20.10.3-0.3-0.10.1-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.50.8-0.70.7-0.80.80.9-0.9-0.5-0.3-0.8-0.8
Pavlov. Cond. response bias0.30.40.6-0.70.7-0.70.70.8-0.8-0.6-0.5-0.5-0.5
Pavlov. Cond. lever latency0.00.00.10.1-0.1-0.20.2-0.30.30.1-0.10.30.2
Pavlov. Cond. magazine entry latency0.60.70.90.9-0.90.7-0.7-0.70.71.00.90.80.9
Pavlov. Cond. change in total contacts0.40.61.1-0.70.7-0.60.61.1-1.1-0.6-0.3-0.8-0.7
Pavlov. Cond. index score0.00.00.10.0-0.00.4-0.30.1-0.10.10.10.10.1
Pavlov. Cond. latency score0.10.10.20.2-0.20.5-0.5-0.10.10.20.20.20.2
Pavlov. Cond. lever contacts0.10.10.3-0.40.40.4-0.30.3-0.3-0.4-0.60.20.2
Pavlov. Cond. magazine entry number0.10.10.2-0.20.2-0.30.30.1-0.1-0.3-0.3-0.4-0.5
Pavlov. Cond. intertrial magazine entries0.60.72.41.0-1.00.2-0.2-0.70.61.01.5-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.2-0.20.5-0.5-0.10.10.20.20.20.2
Pavlov. Cond. response bias0.20.30.80.1-0.10.7-0.7-0.20.20.2-0.20.80.9
Time in closed arm before self-admin3.33.74.8-2.02.0-2.22.22.0-2.0-1.9-1.0-1.8-1.9
Time in closed arm after self-admin0.20.20.3-0.50.50.1-0.10.4-0.4-0.6-0.3-0.4-0.3
Time in open arm before self-admin1.81.92.81.7-1.71.4-1.4-1.61.61.51.10.90.9
Time in open arm after self-admin0.20.20.6-0.50.5-0.60.60.4-0.4-0.3-0.80.40.4
Bone: periosteal estimation0.00.10.5-0.20.20.3-0.30.2-0.2-0.2-0.70.20.2
Bone: periosteal perimeter0.10.20.5-0.50.50.4-0.40.3-0.3-0.5-0.7-0.2-0.3
Bone: post-yield work0.30.40.80.5-0.50.7-0.7-0.50.50.60.30.70.9
Progressive ratio test 1 active lever presses0.20.20.60.6-0.6-0.20.2-0.40.40.50.8-0.4-0.5
Progressive ratio test 1 breakpoint0.20.20.40.6-0.6-0.10.1-0.40.40.40.6-0.3-0.4
Progressive ratio test 1 inactive lever presses0.20.20.50.5-0.50.3-0.3-0.60.60.50.10.60.7
Progressive ratio test 2 active lever presses0.10.10.40.5-0.5-0.40.4-0.0-0.00.30.6-0.4-0.3
Progressive ratio test 2 breakpoint0.30.31.00.8-0.8-0.20.2-0.30.20.61.0-0.4-0.3
Progressive ratio test 2 inactive lever presses0.20.20.30.5-0.50.4-0.5-0.40.40.50.20.40.5
Incentive Sensitization - Responses0.10.10.30.5-0.5-0.10.0-0.20.20.40.20.40.6
Incentive Sensitization - Breakpoint0.30.30.50.7-0.70.2-0.2-0.40.40.60.40.50.7
Sum of active levers in priming session hrs 5-61.11.12.6-1.41.4-0.91.00.6-0.6-1.2-1.6-0.2-0.4
Progressive ratio0.70.82.2-0.30.3-1.21.20.6-0.6-0.30.8-1.4-1.5
Food seeking constrained by brief footshock0.30.30.80.5-0.50.8-0.8-0.60.60.90.5-0.0-0.1
Seeking ratio, punishment vs. effort0.91.12.40.5-0.51.5-1.5-0.91.00.7-0.51.41.4
Retroperitoneal fat weight0.72.23.81.9-1.91.2-1.2-1.31.31.82.00.70.9
Reaction time number correct0.40.51.31.0-1.00.5-0.5-0.60.60.81.1-0.2-0.1
Reaction time mean minus median0.60.81.9-1.31.3-0.50.50.6-0.5-0.9-1.40.30.2
Reaction time mean minus median AUC0.30.41.1-1.01.0-0.50.50.5-0.5-0.6-0.70.10.0
Reaction time num false alarms0.81.21.81.3-1.31.0-1.0-1.21.11.31.20.10.0
Reaction time num false alarms AUC1.31.82.51.6-1.61.3-1.3-1.61.51.61.30.60.5
Reaction time trials correct on left0.40.51.31.0-1.00.5-0.5-0.60.60.81.1-0.2-0.1
Reaction time trials on left0.30.51.21.0-1.00.5-0.5-0.60.50.81.1-0.2-0.1
Reaction time mean1.92.64.2-2.12.1-1.81.81.6-1.6-1.9-1.3-0.7-0.7
Reaction time mean AUC1.82.43.7-1.91.9-1.81.81.6-1.5-1.7-1.0-0.8-0.8
Median of all reaction times2.23.04.1-2.02.0-2.02.01.8-1.8-2.0-1.1-1.0-1.0
Reaction time omissions0.20.30.6-0.70.7-0.30.30.3-0.3-0.6-0.80.60.5
Reaction time false alarm rate0.71.01.51.0-1.01.1-1.1-1.21.21.10.60.70.6
Reaction time premature initiation rate0.00.00.10.1-0.10.00.00.3-0.30.0-0.2-0.3-0.3
Reaction time premature initiations0.10.10.20.5-0.50.2-0.20.0-0.10.30.3-0.5-0.4
Std. dev. reaction times0.91.33.0-1.71.7-0.70.70.9-0.8-1.3-1.70.30.2
Reaction time trials completed0.30.51.21.0-1.00.5-0.5-0.60.50.81.1-0.2-0.1
Reaction time trials AUC0.30.41.01.0-1.00.4-0.4-0.60.50.71.0-0.1-0.1
Run reversals in cocaine runway, females0.40.40.80.6-0.60.7-0.7-0.60.60.70.90.00.0
Run reversals in cocaine runway, males0.70.61.40.8-0.81.2-1.2-0.70.70.80.7-0.2-0.2
Latency to leave start box in cocaine runway2.22.33.61.9-1.91.4-1.4-1.51.51.81.90.70.8
Latency to leave start box in cocaine runway, F1.92.13.11.4-1.41.7-1.8-1.51.51.30.61.51.6
Latency to leave start box in cocaine runway, M1.41.35.41.3-1.30.3-0.3-0.80.71.32.3-0.7-0.7
Std. dev. time between licks in bursts0.40.50.90.4-0.41.0-1.0-0.80.80.3-0.30.90.8
Total sessions with >9 infusions0.30.41.00.7-0.70.2-0.2-0.40.30.61.0-0.7-0.8
Short access day 1 total inactive lever presses1.51.62.71.0-1.01.6-1.6-1.31.41.20.41.31.3
Short access day 10 total inactive lever presses0.10.10.20.3-0.30.4-0.4-0.20.20.40.20.40.5
Short access day 1 total infusions0.40.50.80.7-0.70.7-0.7-0.90.90.80.40.30.2
Short access day 10 total infusions2.73.07.7-1.21.2-1.71.61.6-1.7-1.2-0.3-2.6-2.8
Short access total infusions0.60.62.0-0.30.3-0.90.90.5-0.6-0.3-0.1-1.3-1.4
Short access day 1 locomotion0.10.10.3-0.00.00.5-0.5-0.20.20.1-0.1-0.1-0.2
Short access day 10 total locomotion0.00.00.0-0.10.10.2-0.20.1-0.10.0-0.1-0.0-0.0
Short access total locomotion0.10.20.30.5-0.50.4-0.4-0.40.40.40.40.0-0.0
One hour access (0.3 mA shock)4.95.87.9-2.42.4-2.82.82.5-2.5-2.3-1.6-2.2-2.3
Compulsive drug intake0.20.20.6-0.50.5-0.20.20.3-0.3-0.8-0.80.20.1
One hour access (shock baseline)2.63.04.6-1.51.5-2.12.11.7-1.8-1.3-0.6-1.9-2.0
Social response proportion0.20.30.5-0.50.5-0.60.60.4-0.4-0.7-0.5-0.2-0.2
Social responses0.40.51.0-0.80.8-1.01.00.6-0.6-1.0-0.7-0.1-0.1
Social time2.43.14.3-1.91.9-1.81.82.1-2.0-2.0-1.9-1.0-0.8
Soleus weight1.85.37.02.5-2.52.4-2.4-2.62.62.31.32.12.0
Bone: stiffness0.50.81.11.1-1.10.7-0.7-0.80.81.00.80.81.0
Tibialis anterior weight3.110.714.23.8-3.83.4-3.5-3.73.73.72.81.91.8
Time to tail flick, vehicle, before self-admin0.50.51.0-0.90.9-1.01.00.6-0.6-0.7-0.6-0.1-0.2
Time to tail flick, vehicle, after self-admin1.11.21.7-1.01.0-1.31.31.2-1.3-0.7-0.2-1.2-1.1
Time to tail flick, test, before self-admin0.30.30.90.5-0.50.0-0.1-0.50.40.51.0-0.6-0.8
Time to tail flick, test, after self-admin0.10.10.5-0.10.1-0.40.40.1-0.20.10.1-0.6-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.20.1-0.10.0-0.00.2-0.20.20.4-0.5-0.4
Delta time to tail flick, test, before/after SA1.00.91.5-1.01.0-0.90.91.1-1.1-0.9-1.2-0.5-0.5
Tibia length0.10.30.7-0.30.3-0.40.40.3-0.2-0.5-0.70.70.8
Ambulatory time before self-admin0.10.20.5-0.30.3-0.40.40.2-0.2-0.5-0.70.40.4
Ambulatory time after self-admin1.61.83.81.0-1.01.3-1.3-1.31.41.00.11.92.0
Bone: tissue strength0.10.10.50.5-0.5-0.00.0-0.10.10.60.7-0.2-0.1
Total heroin consumption1.21.52.5-1.21.2-1.61.61.0-1.0-1.4-0.8-1.0-1.1
Bone: trabecular number1.21.93.7-1.71.7-1.01.11.6-1.6-1.6-1.9-0.2-0.0
Bone: trabecular spacing1.21.64.81.6-1.60.4-0.4-1.21.11.72.2-0.00.0
Bone: trabecular thickness3.13.75.3-2.22.2-1.61.62.2-2.2-2.3-2.3-0.8-0.7
Bone: trabecular tissue density0.50.61.00.8-0.80.5-0.5-0.90.90.70.61.01.0
Water consumed over 24 hours0.60.82.0-0.10.1-1.11.10.8-0.9-0.20.5-1.4-1.3
Number of responses in last shaping day0.10.10.2-0.20.2-0.20.2-0.20.2-0.0-0.40.40.4