LOC120093775

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr7_9802860_9804622 0.02 0.02 7.8e-03 0.01 0.01 0.01 0.01 8.2e-03 1.2e-02 9.6e-03 1.2e-02
2 pVTA intron excision ratio chr7_9802860_9804622 0.03 0.03 5.8e-03 0.01 0.02 0.01 0.01 1.9e-02 9.7e-03 4.6e-02 2.8e-02
3 NAcc intron excision ratio chr7_9802860_9804622 0.04 0.03 5.9e-07 0.04 0.04 0.04 0.04 2.5e-07 6.9e-07 2.7e-06 7.3e-07
4 BLA alternative TSS XR_005487460.1 0.05 0.04 1.3e-03 0.05 0.04 0.04 0.04 8.2e-04 4.5e-03 4.7e-03 3.6e-03
5 Brain gene expression LOC120093775 0.04 0.03 2.8e-04 0.04 0.03 0.03 0.03 2.8e-04 6.8e-04 7.5e-04 4.9e-04
6 NAcc gene expression LOC120093775 0.04 0.02 3.3e-07 0.04 0.04 0.03 0.04 2.1e-06 3.4e-06 5.9e-05 2.2e-06
7 PL alternative TSS XR_005487460.1 0.03 0.02 6.2e-04 0.04 0.02 0.02 0.02 8.5e-05 2.3e-03 2.2e-03 9.8e-04
8 BLA intron excision ratio chr7_9802860_9804622 0.05 0.04 8.8e-03 0.04 0.03 0.02 0.02 4.1e-03 1.6e-02 2.2e-02 3.5e-02
9 NAcc alternative TSS XR_005487460.1 0.03 0.02 7.1e-06 0.04 0.03 0.04 0.04 2.7e-06 4.9e-06 4.6e-06 2.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.50.70.8-0.1-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Area under the delay curve1.52.32.7-1.41.6-1.6-1.6-1.6-1.7-1.4-1.4-1.4
BMI with tail6.422.426.0-5.14.9-4.7-4.7-4.7-4.6-4.7-4.6-4.6
BMI without tail1.15.98.2-2.92.7-2.3-2.3-2.3-2.2-2.4-2.3-2.3
Body weight0.94.04.5-2.12.1-2.0-2.0-2.0-1.9-2.1-1.9-1.9
Weight adjusted by age0.10.30.6-0.80.8-0.5-0.5-0.5-0.4-0.6-0.4-0.4
Bone surface0.30.63.82.0-0.8-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Bone volume0.30.63.81.9-0.7-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Breakpoint value in progressive ratio session2.64.75.91.7-2.12.42.32.32.12.22.22.2
Number of licking bursts0.00.10.5-0.70.30.20.20.20.20.20.20.2
Context. condit. distance diff. score0.30.40.5-0.60.7-0.6-0.6-0.6-0.6-0.7-0.6-0.6
Locomotion velocity, session 10.40.41.71.3-0.90.50.50.50.40.40.50.5
Locomotion distance, session 10.20.21.31.1-0.7-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Locomotion velocity, session 23.03.67.52.7-2.41.61.61.61.51.71.71.7
Locomotion distance, session 21.31.85.02.2-1.91.01.01.01.01.11.01.0
Locomotion velocity, session 36.27.17.42.4-2.72.72.72.72.62.72.72.7
Locomotion distance, session 30.00.00.0-0.10.10.10.10.10.00.0-0.0-0.0
Stereotopy head waving bouts, day 34.65.56.82.5-2.62.22.22.22.22.52.32.3
Stereotopy head waving duration, day 35.77.18.42.7-2.82.52.52.52.52.92.72.7
Locomotion velocity, session 70.50.50.91.0-0.60.80.80.80.80.60.70.7
Locomotion distance, session 70.10.10.6-0.70.6-0.1-0.1-0.1-0.1-0.3-0.2-0.2
Stereotopy head waving bouts, day 70.10.10.20.4-0.1-0.4-0.4-0.4-0.4-0.1-0.3-0.3
Stereotopy head waving duration, day 70.20.31.31.1-0.80.20.20.20.20.40.30.3
Locomotion velocity, session 80.40.52.21.5-1.00.30.30.30.30.40.40.4
Locomotion distance, session 80.10.10.50.7-0.60.20.20.20.20.20.20.2
Degree of sensitization distance0.40.50.6-0.60.7-0.7-0.7-0.7-0.7-0.8-0.7-0.7
Degree of sensitization stereotypy1.92.12.5-0.91.3-1.5-1.5-1.5-1.6-1.4-1.5-1.5
Conditioned locomotion1.01.22.9-1.71.4-1.0-1.0-1.0-0.9-0.9-0.9-0.9
Cocaine response after cond. corrected3.65.49.2-3.02.8-2.1-2.1-2.1-2.1-2.1-2.1-2.1
Cocaine response after cond. not corrected3.95.710.1-3.22.9-2.2-2.2-2.2-2.2-2.2-2.2-2.2
Cocaine response before conditioning0.40.50.80.9-0.80.60.60.60.70.70.70.7
Saline control response0.10.10.4-0.70.4-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Bone: connectivity density0.40.70.90.20.4-1.0-1.0-1.0-1.0-0.9-0.9-0.9
Bone: cortical apparent density0.71.21.3-0.91.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1
Bone: cortical area0.50.81.00.10.7-1.0-1.0-1.0-1.0-1.0-1.0-1.0
Bone: cortical porosity0.10.10.60.8-0.50.20.20.20.20.20.20.2
Bone: cortical porosity0.10.10.50.7-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2
Bone: cortical thickness1.11.92.2-0.71.2-1.5-1.5-1.5-1.5-1.5-1.4-1.4
Bone: cortical thickness0.10.10.2-0.30.10.40.40.40.40.40.40.4
Bone: cortical tissue density0.50.80.8-0.70.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9
Condit. Reinf. active minus inactive responses4.14.75.12.1-2.32.22.22.22.12.22.12.1
Condit. Reinf. active-inactive response ratio2.32.52.81.2-1.41.71.71.71.61.61.61.6
Condit. Reinf. active responses3.34.36.12.5-2.41.91.91.91.92.02.02.0
Condit. Reinf. inactive responses0.60.82.41.6-1.20.60.60.60.60.50.80.8
Incentive salience index mean1.92.43.51.9-1.91.51.51.51.41.51.41.4
Condit. Reinf. lever presses0.10.10.60.8-0.5-0.2-0.2-0.2-0.3-0.3-0.2-0.2
Condit. Reinf. active minus inactive responses2.23.43.91.2-1.62.02.02.01.91.91.91.9
Condit. Reinf. active-inactive response ratio0.20.30.4-0.5-0.10.60.60.60.60.60.60.6
Condit. Reinf. active responses2.43.43.71.6-1.71.91.91.91.91.91.91.9
Condit. Reinf. inactive responses1.01.42.01.4-1.21.21.21.21.21.21.21.2
Condit. Reinf. lever presses2.02.93.21.3-1.51.81.81.81.81.81.81.8
Condit. Reinf. lever reinforcers received1.92.62.91.2-1.41.71.71.71.71.71.71.7
Conditioned reinforcement - actives0.41.62.20.7-1.11.51.51.51.51.11.11.1
Conditioned reinforcement - inactives0.00.00.2-0.40.20.10.10.1-0.1-0.1-0.2-0.2
Conditioned locomotion6.79.911.63.0-3.23.43.43.43.13.02.92.9
Patch foraging indifference point 0 sec0.10.30.4-0.30.5-0.6-0.6-0.6-0.5-0.6-0.5-0.5
Patch foraging indifference point AUC0.61.41.70.8-1.11.31.31.31.21.11.21.2
Delay disc. indifference point, 0s delay8.59.610.8-2.22.6-3.2-3.3-3.3-3.3-3.2-3.3-3.3
Delay disc. indifference point, 16s delay0.10.20.3-0.30.4-0.5-0.4-0.4-0.5-0.4-0.3-0.3
Delay disc. indifference point, 2s delay6.67.48.2-2.22.6-2.8-2.9-2.9-2.8-2.6-2.8-2.8
Delay disc. indifference point, 24s delay0.30.40.8-0.70.9-0.7-0.6-0.6-0.7-0.7-0.5-0.5
Delay disc. indifference point, 4s delay1.41.52.0-0.71.2-1.4-1.3-1.3-1.4-1.0-1.2-1.2
Delay disc. indifference point, 8s delay0.71.11.8-1.31.4-1.0-1.0-1.0-1.1-0.9-0.9-0.9
Indifference point function ln k0.10.20.3-0.50.6-0.4-0.4-0.4-0.4-0.4-0.5-0.5
Indifference point function log k0.10.20.3-0.50.6-0.4-0.4-0.4-0.4-0.4-0.5-0.5
Patch foraging total patch changes 0 sec0.10.20.3-0.30.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5
Patch foraging total patch changes 12 sec0.30.41.3-1.10.8-0.5-0.5-0.5-0.5-0.5-0.4-0.4
Patch foraging total patch changes 18 sec0.51.21.31.1-1.21.01.01.01.11.11.11.1
Patch foraging total patch changes 24 sec0.00.10.10.2-0.40.20.20.20.30.30.30.3
Patch foraging total patch changes 6 sec0.20.30.60.8-0.60.50.50.50.50.40.50.5
Patch foraging time to switch 0 sec0.72.53.2-0.71.0-1.8-1.8-1.8-1.7-1.7-1.7-1.7
Patch foraging water rate 0 sec0.10.20.5-0.70.30.50.50.50.50.40.40.4
Patch foraging water rate 12 sec0.31.13.5-1.91.5-0.8-0.8-0.8-0.8-0.8-0.8-0.8
Patch foraging water rate 18 sec0.30.81.3-1.20.20.90.90.90.90.90.80.8
Patch foraging water rate 24 sec0.40.53.5-1.91.10.00.00.0-0.0-0.1-0.1-0.1
Patch foraging water rate 6 sec0.60.91.2-0.2-0.31.11.11.11.11.11.11.1
Seeking ratio, delayed vs. immediate footshock3.34.85.62.4-2.42.22.22.22.12.12.12.1
Distance traveled before self-admin0.10.20.4-0.10.3-0.3-0.3-0.3-0.6-0.6-0.6-0.6
Distance traveled after self-admin0.00.00.10.1-0.20.20.30.30.1-0.00.10.1
Extensor digitorum longus weight4.016.120.9-4.64.5-3.8-3.8-3.8-3.9-3.9-3.9-3.9
Bone: elastic displacement0.20.20.30.5-0.40.40.40.40.40.40.40.4
Bone: elastic work0.30.40.5-0.10.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Bone: endosteal estimation0.20.50.5-0.30.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Bone: endosteal perimeter0.20.41.41.2-0.80.50.50.50.50.60.50.5
Epididymis fat weight0.00.10.7-0.80.30.20.20.20.10.40.20.2
Delta time in closed arm before/after self-admin0.50.52.6-1.61.0-0.1-0.1-0.1-0.2-0.3-0.3-0.3
Delta time in open arm before/after self-admin0.50.60.8-0.60.8-0.8-0.8-0.8-0.9-0.7-0.7-0.7
Diff in mean of infusions in LGA sessions1.12.02.61.3-1.51.61.41.41.21.51.51.5
Delay discount exponential model param1.31.82.31.2-1.51.41.41.41.51.21.31.3
Extinction: sum of active levers before priming0.81.21.80.4-0.91.31.31.31.11.01.11.1
Active lever presses in extinction session 62.62.63.21.6-1.71.81.81.81.51.31.51.5
Bone: final force1.42.32.7-0.61.4-1.6-1.6-1.6-1.6-1.6-1.6-1.6
Bone: final moment1.21.92.2-0.51.2-1.5-1.5-1.5-1.5-1.5-1.5-1.5
Food consumed during 24 hour testing period0.30.70.9-1.00.9-0.8-0.8-0.8-0.8-0.8-0.8-0.8
Glucose2.53.94.6-2.12.1-1.9-1.9-1.9-2.0-2.0-1.9-1.9
Heart weight0.71.11.40.1-0.71.11.11.11.11.21.21.2
Delay discount hyperbolic model param2.63.33.91.6-1.91.91.91.92.01.71.81.8
Intermittent access intake day 1-15 change1.47.48.52.0-2.52.92.92.92.92.62.82.8
Intermittent access intake escalation1.26.57.41.9-2.32.72.72.72.72.52.62.6
Intermittent access intake escalation 23.45.86.52.0-2.22.52.52.52.52.32.52.5
Intermitt. access day 1 inactive lever presses0.00.61.2-0.5-0.11.11.11.10.60.60.50.5
Intermitt. access day 15 inactive lever presses0.10.40.60.7-0.70.80.80.80.60.70.50.5
Intermitt. access escalation Index0.41.21.7-0.40.8-1.2-1.2-1.2-1.1-1.3-1.2-1.2
Intermittent access day 1 total infusions0.10.20.5-0.1-0.20.70.70.70.40.50.30.3
Intermittent access day 15 total infusions1.64.05.11.5-1.82.32.32.32.01.91.91.9
Intermittent access terminal intake (last 3 days)1.52.63.51.2-1.51.91.91.91.61.51.51.5
Intermittent access total infusions1.01.21.70.7-1.01.31.31.31.11.01.01.0
Intermittent access day 1 locomotion1.12.02.60.6-1.11.61.61.61.41.51.41.4
Intermittent access day 15 total locomotion1.55.87.31.7-2.32.72.72.72.42.32.42.4
Intermittent access total locomotion2.53.04.01.1-1.62.02.02.01.81.61.61.6
Intermittent access standard deviation1.58.19.22.8-2.83.03.03.02.82.72.72.7
Left kidney weight0.00.10.2-0.50.30.20.20.20.20.10.10.1
Right kidney weight0.32.32.80.9-1.11.71.71.71.61.61.71.7
Cocaine induced anxiety0.51.33.21.8-1.50.90.90.91.00.90.90.9
Post-drug Anxiety0.91.03.01.7-1.40.70.70.70.70.90.90.9
Baseline Anxiety0.00.10.10.2-0.20.30.30.30.10.30.30.3
Tail length2.613.814.63.5-3.63.83.83.83.83.73.73.7
Length with tail2.08.79.12.8-2.93.03.03.03.02.93.03.0
Length without tail0.00.00.0-0.10.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Times rat made contact with spout0.10.10.6-0.80.6-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Lifetime Intake0.50.61.00.4-0.71.01.01.00.80.80.70.7
Liver weight, left0.91.62.1-1.41.3-1.3-1.3-1.3-1.3-1.2-1.1-1.1
Liver weight, right0.50.91.4-1.21.2-0.8-0.8-0.8-0.9-1.0-1.0-1.0
Locomotor activity2.94.67.32.7-2.42.02.02.02.01.92.02.0
Locomotor testing distance1.22.94.72.2-2.01.61.61.61.61.51.61.6
Locomotor testing rearing0.00.10.1-0.0-0.10.30.30.30.30.40.40.4
Locomotion in novel chamber1.21.62.20.7-1.11.51.51.51.31.11.21.2
Locomotion in novel chamber post-restriction0.61.82.21.3-1.21.31.31.31.41.51.41.4
Fecal boli incidents, locomotor time 10.71.92.7-1.61.4-1.2-1.3-1.3-1.3-1.6-1.3-1.3
Change in fecal boli incidents, locomotor task0.30.31.11.0-0.50.50.40.40.40.20.40.4
Time >=10cm from walls, locomotor time 10.40.51.40.10.4-0.7-0.6-0.6-0.6-1.2-0.7-0.7
Bouts of movement, locomotor time 10.30.40.50.5-0.50.70.70.70.70.50.70.7
Total resting periods, locomotor time 10.40.50.60.7-0.60.70.70.70.70.50.80.8
Rest time, locomotor task time 10.10.20.40.6-0.60.50.40.40.40.20.40.4
Distance moved, locomotor task time 10.30.91.2-0.20.7-1.1-1.0-1.0-1.0-1.1-1.0-1.0
Vertical activity count, locomotor time 10.00.10.4-0.50.6-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Time >=10cm from walls, locomotor time 20.41.11.7-1.21.3-1.0-0.9-0.9-0.9-1.2-0.9-0.9
Bouts of movement, locomotor time 20.10.31.01.0-0.80.30.30.30.30.50.30.3
Total resting periods, locomotor time 20.10.21.01.0-0.70.20.30.30.30.50.20.2
Rest time, locomotor task time 20.40.71.71.3-1.00.60.70.70.70.70.80.8
Distance moved, locomotor task time 20.50.71.5-1.20.9-0.7-0.7-0.7-0.7-0.7-0.8-0.8
Vertical activity count, locomotor time 20.20.52.0-1.41.0-0.4-0.5-0.5-0.5-0.6-0.6-0.6
Light reinforcement 12.29.912.33.5-3.53.03.03.03.13.03.13.1
Light reinforcement 21.12.53.61.9-1.81.51.51.51.51.51.51.5
Bone: marrow area0.20.50.5-0.30.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Bone: maximum diameter0.71.43.51.9-1.41.01.01.01.01.01.01.0
Bone: maximum force1.22.42.7-0.81.5-1.6-1.6-1.6-1.6-1.6-1.6-1.6
Bone: maximum moment1.12.02.3-0.71.4-1.5-1.5-1.5-1.5-1.5-1.5-1.5
Mean time between licks in bursts1.16.66.72.4-2.62.62.62.62.62.62.62.6
Mean num. licks in bursts0.00.10.10.10.1-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Cd content in liver0.20.20.40.6-0.50.40.40.40.40.40.40.4
Co content in liver1.82.12.31.2-1.41.51.51.51.51.51.51.5
Cu content in liver0.20.21.01.0-0.60.30.30.30.20.20.20.2
Fe content in liver0.20.20.30.1-0.40.50.50.50.50.50.50.5
K content in liver0.00.00.30.5-0.3-0.0-0.0-0.0-0.1-0.1-0.1-0.1
Mg content in liver0.20.30.60.8-0.70.40.40.40.50.50.40.4
Mn content in liver1.11.34.72.2-1.50.70.70.70.80.80.80.8
Na content in liver1.01.11.4-0.50.7-1.1-1.1-1.1-1.2-1.2-1.2-1.2
Rb content in liver0.10.10.60.8-0.3-0.3-0.3-0.3-0.2-0.2-0.2-0.2
Se content in liver0.20.30.30.3-0.50.50.50.50.50.50.50.5
Sr content in liver0.00.00.1-0.30.20.00.00.00.00.00.00.0
Zn content in liver4.55.36.41.2-1.92.52.52.52.42.42.42.4
Bone: minimum diameter0.00.10.10.40.1-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Time in familiar zone, hab. session 12.02.22.81.2-1.31.41.41.41.51.71.71.7
Time in novel zone, hab. session 11.11.31.8-0.40.9-1.1-1.1-1.1-1.2-1.3-1.3-1.3
Total zone transitions, hab. session 10.70.92.71.6-1.40.70.70.70.70.90.80.8
Total locomotion distance, hab. session 10.81.24.52.1-1.50.60.60.60.70.90.80.8
Locomotion velocity, hab. session 11.21.84.72.2-1.81.01.01.01.01.21.11.1
Time in familiar zone, hab. session 26.37.27.92.0-2.52.82.82.82.82.82.82.8
Time in novel zone, hab. session 24.85.35.9-1.62.1-2.4-2.4-2.4-2.4-2.4-2.4-2.4
Total zone transitions, hab. session 20.50.60.80.5-0.0-0.9-0.9-0.9-0.9-0.8-0.8-0.8
Total locomotion distance, hab. session 20.81.02.71.7-1.50.70.70.70.71.00.90.9
Locomotion velocity, hab. session 20.71.03.11.8-1.50.60.60.60.60.90.80.8
Novel to familiar place preference ratio3.85.06.3-1.41.9-2.3-2.3-2.3-2.4-2.5-2.4-2.4
Novelty place preference2.43.14.0-1.01.5-1.8-1.8-1.8-1.9-2.0-1.9-1.9
Time in novel zone, NPP test2.93.54.4-1.11.6-1.9-1.9-1.9-2.0-2.1-2.0-2.0
Total zone transitions, NPP test0.10.10.20.4-0.3-0.4-0.4-0.4-0.4-0.2-0.3-0.3
Total locomotion distance, NPP test0.10.20.30.5-0.2-0.5-0.5-0.5-0.5-0.2-0.4-0.4
Locomotion velocity, NPP test0.10.10.70.8-0.5-0.2-0.2-0.2-0.20.1-0.1-0.1
Intraocular pressure0.10.20.8-0.90.30.40.40.40.40.30.40.4
Delta distance traveled before/after self-admin0.50.50.80.4-0.60.60.70.70.90.70.90.9
Delta ambulatory time before/after self-admin0.20.40.70.5-0.60.50.60.60.80.60.70.7
Parametrial fat weight0.00.00.00.1-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.2
Pavlov. Cond. lever latency0.10.10.3-0.50.30.30.30.30.30.10.30.3
Pavlov. Cond. magazine entry latency3.03.84.31.7-2.11.91.91.92.02.02.02.0
Pavlov. Cond. change in total contacts0.00.00.10.2-0.30.20.20.20.20.20.20.2
Pavlov. Cond. index score0.30.40.70.8-0.80.50.50.50.50.70.60.6
Pavlov. Cond. latency score0.30.30.90.9-0.90.40.40.40.40.60.50.5
Pavlov. Cond. lever contacts0.10.10.10.4-0.2-0.3-0.3-0.3-0.3-0.1-0.3-0.3
Pavlov. Cond. magazine entry number0.81.01.2-0.81.0-0.9-0.9-0.9-1.0-1.1-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.20.30.40.0-0.20.60.60.60.60.60.60.6
Pavlov. Cond. lever-magazine prob. diff.0.40.50.90.9-0.90.60.60.60.60.80.70.7
Pavlov. Cond. response bias0.80.91.10.8-1.00.90.90.91.01.11.01.0
Pavlov. Cond. lever latency0.81.11.3-1.20.9-1.1-1.1-1.1-1.1-1.0-1.1-1.1
Pavlov. Cond. magazine entry latency0.40.50.70.9-0.60.70.70.70.70.60.70.7
Pavlov. Cond. change in total contacts0.41.01.10.8-0.81.11.11.11.01.01.01.0
Pavlov. Cond. index score0.61.01.11.0-0.81.01.01.01.00.91.01.0
Pavlov. Cond. latency score0.61.01.31.1-0.91.01.01.01.00.91.01.0
Pavlov. Cond. lever contacts0.60.91.00.9-0.71.01.01.01.00.91.01.0
Pavlov. Cond. magazine entry number0.70.91.2-1.10.9-1.0-1.0-1.0-0.9-0.9-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.10.30.8-0.90.7-0.5-0.5-0.5-0.5-0.5-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.71.01.31.2-0.91.01.01.01.00.91.01.0
Pavlov. Cond. response bias1.72.42.61.4-1.31.61.61.61.61.51.61.6
Time in closed arm before self-admin0.50.81.2-0.20.5-1.1-1.1-1.1-0.8-0.9-1.0-1.0
Time in closed arm after self-admin0.20.20.3-0.0-0.30.40.40.40.60.50.60.6
Time in open arm before self-admin0.20.20.30.5-0.40.60.50.50.60.20.20.2
Time in open arm after self-admin0.91.01.3-0.91.1-0.9-0.9-0.9-1.0-1.0-1.1-1.1
Bone: periosteal estimation0.30.70.90.10.5-0.9-0.9-0.9-0.9-0.9-0.9-0.9
Bone: periosteal perimeter0.10.21.11.0-0.50.10.10.10.10.10.10.1
Bone: post-yield work0.50.91.1-0.91.1-1.0-1.0-1.0-1.0-0.9-0.9-0.9
Progressive ratio test 1 active lever presses0.10.10.2-0.30.00.40.40.40.30.40.30.3
Progressive ratio test 1 breakpoint0.10.10.2-0.40.00.40.40.40.30.40.30.3
Progressive ratio test 1 inactive lever presses0.10.40.70.3-0.40.80.80.80.60.50.40.4
Progressive ratio test 2 active lever presses0.30.40.9-0.2-0.20.90.90.90.70.50.50.5
Progressive ratio test 2 breakpoint0.40.51.0-0.2-0.31.01.01.00.70.60.60.6
Progressive ratio test 2 inactive lever presses0.10.20.30.2-0.40.60.60.60.40.20.20.2
Incentive Sensitization - Responses0.00.10.5-0.70.30.30.30.30.2-0.10.00.0
Incentive Sensitization - Breakpoint0.00.10.3-0.50.10.40.40.40.3-0.00.20.2
Sum of active levers in priming session hrs 5-60.00.00.0-0.20.10.20.00.0-0.0-0.2-0.2-0.2
Progressive ratio0.10.41.7-1.30.6-0.4-0.4-0.4-0.5-0.4-0.3-0.3
Food seeking constrained by brief footshock0.10.10.30.1-0.60.30.30.30.30.40.30.3
Seeking ratio, punishment vs. effort0.10.31.11.0-0.70.40.40.40.40.50.30.3
Retroperitoneal fat weight0.41.64.3-2.11.5-1.0-1.0-1.0-1.2-1.0-1.1-1.1
Reaction time number correct0.10.52.0-1.41.1-0.5-0.5-0.5-0.4-0.4-0.5-0.5
Reaction time mean minus median0.10.80.90.8-0.81.01.01.00.90.90.90.9
Reaction time mean minus median AUC0.00.10.30.5-0.0-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Reaction time num false alarms0.10.10.4-0.60.6-0.1-0.1-0.1-0.2-0.2-0.2-0.2
Reaction time num false alarms AUC0.10.10.6-0.80.7-0.1-0.1-0.1-0.2-0.2-0.2-0.2
Reaction time trials correct on left0.10.52.0-1.41.1-0.5-0.5-0.5-0.4-0.4-0.5-0.5
Reaction time trials on left0.20.51.9-1.41.1-0.5-0.5-0.5-0.5-0.4-0.5-0.5
Reaction time mean0.00.10.10.30.1-0.3-0.3-0.3-0.3-0.3-0.3-0.3
Reaction time mean AUC0.00.10.20.30.2-0.3-0.3-0.3-0.3-0.4-0.3-0.3
Median of all reaction times0.30.50.6-0.10.5-0.8-0.8-0.8-0.7-0.8-0.7-0.7
Reaction time omissions0.10.20.60.8-0.60.30.30.30.20.10.20.2
Reaction time false alarm rate0.00.00.1-0.10.3-0.1-0.1-0.1-0.2-0.2-0.2-0.2
Reaction time premature initiation rate1.01.61.90.9-1.11.31.31.31.31.31.41.4
Reaction time premature initiations0.41.11.50.2-0.61.11.11.11.21.21.21.2
Std. dev. reaction times0.10.20.40.6-0.40.40.40.40.40.30.40.4
Reaction time trials completed0.20.51.9-1.41.1-0.5-0.5-0.5-0.5-0.4-0.5-0.5
Reaction time trials AUC0.10.52.1-1.51.1-0.4-0.4-0.4-0.4-0.4-0.4-0.4
Run reversals in cocaine runway, females0.40.40.91.0-0.90.60.60.60.50.60.50.5
Run reversals in cocaine runway, males1.31.42.11.4-1.41.11.11.11.11.31.11.1
Latency to leave start box in cocaine runway0.40.51.61.3-1.00.60.60.60.40.30.40.4
Latency to leave start box in cocaine runway, F0.20.20.50.7-0.3-0.2-0.2-0.2-0.5-0.6-0.5-0.5
Latency to leave start box in cocaine runway, M2.22.12.31.1-1.31.51.51.51.51.41.51.5
Std. dev. time between licks in bursts0.50.92.11.5-1.00.80.80.80.80.80.80.8
Total sessions with >9 infusions0.30.30.60.2-0.40.80.80.80.60.50.30.3
Short access day 1 total inactive lever presses0.20.30.50.5-0.60.70.70.70.70.60.40.4
Short access day 10 total inactive lever presses0.00.20.4-0.50.10.60.60.60.30.20.10.1
Short access day 1 total infusions0.20.30.40.6-0.60.60.60.60.60.50.40.4
Short access day 10 total infusions0.10.10.3-0.2-0.10.50.50.50.20.40.20.2
Short access total infusions0.30.40.60.3-0.50.80.80.80.50.60.50.5
Short access day 1 locomotion1.01.72.41.2-1.21.51.51.51.31.11.01.0
Short access day 10 total locomotion2.08.310.32.0-2.63.23.23.23.02.92.82.8
Short access total locomotion1.92.94.01.3-1.62.02.02.01.71.61.51.5
One hour access (0.3 mA shock)0.00.00.1-0.30.20.00.00.0-0.1-0.0-0.3-0.3
Compulsive drug intake1.11.62.1-0.30.8-1.4-1.4-1.4-1.4-1.4-1.4-1.4
One hour access (shock baseline)0.20.61.00.1-0.50.90.90.90.81.00.70.7
Social response proportion0.70.81.31.1-1.10.80.80.80.80.90.90.9
Social responses7.09.211.43.4-3.23.03.03.02.92.92.92.9
Social time0.30.50.7-0.90.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Soleus weight8.625.427.4-4.75.2-5.1-5.1-5.1-5.0-5.0-5.0-5.0
Bone: stiffness2.64.75.1-1.52.1-2.3-2.3-2.3-2.3-2.2-2.2-2.2
Tibialis anterior weight1.13.64.1-1.92.0-1.7-1.7-1.7-2.0-1.9-2.0-2.0
Time to tail flick, vehicle, before self-admin0.00.10.10.4-0.30.30.20.20.20.20.10.1
Time to tail flick, vehicle, after self-admin0.30.51.0-0.1-0.30.80.70.70.70.91.01.0
Time to tail flick, test, before self-admin0.20.20.90.9-0.60.10.20.20.50.40.30.3
Time to tail flick, test, after self-admin0.10.10.10.2-0.30.10.30.30.30.30.30.3
Delta time to tail flick, vehicle, before/after SA0.20.21.0-1.00.7-0.2-0.2-0.2-0.3-0.00.10.1
Delta time to tail flick, test, before/after SA0.10.10.3-0.50.20.20.30.30.20.30.30.3
Tibia length0.92.62.91.4-1.51.61.61.61.61.71.61.6
Ambulatory time before self-admin0.10.20.4-0.20.3-0.2-0.2-0.2-0.6-0.6-0.6-0.6
Ambulatory time after self-admin0.00.00.00.1-0.10.10.10.1-0.0-0.2-0.1-0.1
Bone: tissue strength1.92.02.2-1.11.3-1.5-1.5-1.5-1.5-1.5-1.5-1.5
Total heroin consumption1.51.82.31.3-1.51.51.31.31.31.31.21.2
Bone: trabecular number0.20.51.91.4-0.90.40.40.40.40.50.40.4
Bone: trabecular spacing0.30.42.8-1.71.0-0.1-0.1-0.1-0.1-0.2-0.2-0.2
Bone: trabecular thickness0.50.72.11.4-0.3-0.7-0.7-0.7-0.7-0.8-0.7-0.7
Bone: trabecular tissue density1.11.83.0-1.71.4-1.3-1.3-1.3-1.3-1.3-1.3-1.3
Water consumed over 24 hours0.51.01.1-0.60.9-1.1-1.1-1.1-1.1-1.1-1.1-1.1
Number of responses in last shaping day1.51.92.50.9-1.21.61.61.61.41.41.31.3