Hub : Genes

LOC120093705

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	IC	gene expression	LOC120093705	0.08	0.05	7.0e-03	0.04	0.04	0.01	0.04	1.3e-02	1.3e-02	9.8e-02	7.2e-03
2	PL	gene expression	LOC120093705	0.05	0.03	2.8e-04	0.04	0.03	0.03	0.04	1.1e-05	2.5e-04	1.3e-04	1.5e-05
3	PL	mRNA stability	LOC120093705	0.07	0.04	4.2e-05	0.01	0.04	0.03	0.03	1.2e-02	7.2e-05	1.5e-04	2.7e-04
4	Brain	mRNA stability	LOC120093705	0.1	0.06	4.7e-06	0.07	0.06	0.08	0.08	2.9e-07	1.1e-06	1.3e-07	1.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.5	1.0	1.6	1.2	-1.3	0.8	-0.5
Area under the delay curve	1.6	2.4	4.3	2.1	-1.8	1.1	-0.8
BMI with tail	0.7	2.6	7.0	-1.0	0.6	1.4	-2.6
BMI without tail	0.1	0.6	1.5	-0.4	-0.3	0.8	-1.2
Body weight	0.5	2.4	4.8	-2.2	1.7	-0.2	-1.3
Weight adjusted by age	0.2	0.6	1.7	-1.3	0.7	-0.1	-0.2
Bone surface	0.3	0.5	0.8	0.9	-0.8	0.6	-0.6
Bone volume	0.2	0.3	0.6	0.8	-0.7	0.4	-0.3
Breakpoint value in progressive ratio session	0.3	0.5	1.0	0.5	-0.6	1.0	-0.7
Number of licking bursts	0.1	0.3	0.9	-0.1	-0.2	-1.0	0.6
Context. condit. distance diff. score	1.5	1.8	4.2	-1.3	2.0	-0.9	0.7
Locomotion velocity, session 1	0.9	1.0	1.6	-1.3	1.1	-0.8	0.5
Locomotion distance, session 1	0.6	0.7	1.9	-0.2	0.6	-0.8	1.4
Locomotion velocity, session 2	1.4	1.7	4.1	-2.0	1.2	-1.0	-0.3
Locomotion distance, session 2	0.4	0.6	0.8	0.6	-0.8	0.9	-0.7
Locomotion velocity, session 3	6.1	7.0	8.2	-2.9	2.8	-2.9	1.9
Locomotion distance, session 3	2.1	2.4	3.3	-1.4	1.1	-1.8	1.8
Stereotopy head waving bouts, day 3	0.5	0.6	1.1	-0.8	1.1	-0.3	-0.7
Stereotopy head waving duration, day 3	1.2	1.5	3.0	-1.4	1.7	-0.5	-0.8
Locomotion velocity, session 7	2.3	2.6	3.5	-1.9	1.9	-1.6	0.8
Locomotion distance, session 7	0.4	0.5	0.7	-0.7	0.6	-0.8	0.8
Stereotopy head waving bouts, day 7	2.6	3.1	4.7	-2.2	2.1	-1.7	0.6
Stereotopy head waving duration, day 7	1.3	1.6	2.5	-1.6	1.5	-1.3	0.3
Locomotion velocity, session 8	2.0	2.5	4.9	-2.2	2.0	-0.5	-0.8
Locomotion distance, session 8	1.0	1.5	2.5	-1.3	1.6	-1.0	0.8
Degree of sensitization distance	0.8	0.9	1.6	0.5	-0.2	1.3	-1.3
Degree of sensitization stereotypy	1.3	1.4	2.3	-1.5	1.4	-1.1	0.4
Conditioned locomotion	0.2	0.2	0.4	-0.2	0.6	-0.1	0.5
Cocaine response after cond. corrected	0.0	0.1	0.1	-0.2	-0.1	-0.4	0.3
Cocaine response after cond. not corrected	0.4	0.6	1.0	-0.7	0.1	-1.0	0.9
Cocaine response before conditioning	0.3	0.4	1.0	-0.2	0.1	-0.7	1.0
Saline control response	0.6	0.8	2.8	-0.3	0.3	-0.2	1.7
Bone: connectivity density	0.2	0.3	0.6	0.7	-0.7	0.2	-0.4
Bone: cortical apparent density	0.3	0.5	1.5	1.2	-0.5	0.3	0.3
Bone: cortical area	0.3	0.5	1.0	-1.0	1.0	0.2	-0.3
Bone: cortical porosity	0.3	0.3	0.7	-0.0	-0.2	0.8	-0.7
Bone: cortical porosity	0.3	0.3	0.6	-0.2	-0.1	0.8	-0.7
Bone: cortical thickness	0.2	0.3	0.9	0.6	-0.0	0.9	-0.3
Bone: cortical thickness	0.6	0.8	1.8	0.2	0.5	1.4	-1.0
Bone: cortical tissue density	0.2	0.4	1.2	1.1	-0.4	0.3	0.3
Condit. Reinf. active minus inactive responses	0.6	0.7	1.2	1.1	-1.0	0.7	-0.4
Condit. Reinf. active-inactive response ratio	0.6	0.7	1.7	1.3	-0.9	0.5	-0.1
Condit. Reinf. active responses	0.3	0.4	0.9	0.9	-0.9	0.1	0.2
Condit. Reinf. inactive responses	0.3	0.3	0.8	-0.1	-0.1	-0.7	0.9
Incentive salience index mean	0.0	0.0	0.1	0.2	-0.2	-0.0	0.3
Condit. Reinf. lever presses	0.6	0.9	1.3	-1.1	0.7	-0.9	1.0
Condit. Reinf. active minus inactive responses	0.4	0.7	1.3	0.3	-0.6	1.0	-1.1
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.5	0.3	-0.5	0.4	-0.7
Condit. Reinf. active responses	0.5	0.7	1.7	-0.3	-0.1	1.0	-1.3
Condit. Reinf. inactive responses	0.5	0.7	0.8	-0.9	0.8	0.7	-0.9
Condit. Reinf. lever presses	0.2	0.3	0.9	-0.6	0.1	0.3	-1.0
Condit. Reinf. lever reinforcers received	0.5	0.7	1.6	-0.0	-0.3	1.1	-1.3
Conditioned reinforcement - actives	0.0	0.1	0.2	0.1	0.2	-0.1	0.5
Conditioned reinforcement - inactives	0.0	0.0	0.1	-0.2	0.2	0.1	0.3
Conditioned locomotion	0.6	0.9	1.7	-1.3	0.9	-1.0	0.4
Patch foraging indifference point 0 sec	0.1	0.3	0.9	0.2	-0.9	0.4	-0.5
Patch foraging indifference point AUC	0.1	0.2	0.3	0.6	-0.5	0.2	0.2
Delay disc. indifference point, 0s delay	0.1	0.1	0.3	0.1	-0.3	0.3	-0.5
Delay disc. indifference point, 16s delay	1.6	2.3	4.7	2.2	-1.7	1.1	-0.6
Delay disc. indifference point, 2s delay	0.9	1.0	1.5	1.2	-1.1	0.9	-0.7
Delay disc. indifference point, 24s delay	0.6	1.0	1.5	0.7	-0.8	1.1	-1.2
Delay disc. indifference point, 4s delay	3.1	3.3	5.3	2.3	-2.1	1.4	-1.2
Delay disc. indifference point, 8s delay	1.2	2.1	3.6	1.9	-1.7	1.0	-0.9
Indifference point function ln k	0.9	2.6	4.3	-2.1	2.0	-1.1	0.8
Indifference point function log k	0.9	2.6	4.3	-2.1	2.0	-1.1	0.8
Patch foraging total patch changes 0 sec	0.1	0.2	0.7	0.2	-0.9	0.2	-0.2
Patch foraging total patch changes 12 sec	0.1	0.2	0.3	0.3	-0.6	0.4	-0.5
Patch foraging total patch changes 18 sec	0.1	0.3	0.6	0.6	-0.8	0.0	0.3
Patch foraging total patch changes 24 sec	0.1	0.4	0.7	-0.6	0.1	-0.8	0.6
Patch foraging total patch changes 6 sec	0.7	1.2	2.5	1.0	-1.6	0.9	-0.7
Patch foraging time to switch 0 sec	0.1	0.3	0.5	0.6	-0.4	0.4	-0.7
Patch foraging water rate 0 sec	0.0	0.2	0.6	-0.8	0.1	-0.0	-0.3
Patch foraging water rate 12 sec	0.3	1.1	2.4	-1.6	0.3	-1.1	0.9
Patch foraging water rate 18 sec	0.0	0.1	0.2	-0.3	-0.4	-0.1	-0.0
Patch foraging water rate 24 sec	0.1	0.1	0.4	-0.7	0.1	-0.0	-0.3
Patch foraging water rate 6 sec	0.7	1.0	2.0	-0.7	0.6	-1.1	1.4
Seeking ratio, delayed vs. immediate footshock	0.5	0.7	1.8	0.9	-1.3	0.3	-0.2
Distance traveled before self-admin	0.5	1.1	1.5	-0.7	1.1	-1.1	1.2
Distance traveled after self-admin	0.1	0.2	0.6	-0.8	0.3	-0.3	0.4
Extensor digitorum longus weight	0.2	0.8	1.9	-1.4	0.8	-0.7	-0.4
Bone: elastic displacement	0.5	0.6	1.5	-1.2	0.3	-0.7	0.7
Bone: elastic work	1.0	1.3	3.4	-1.9	1.2	-0.2	-0.6
Bone: endosteal estimation	1.0	2.4	5.8	-2.4	1.7	-0.9	-0.5
Bone: endosteal perimeter	1.4	3.5	8.5	-2.9	2.0	-1.3	0.0
Epididymis fat weight	0.2	1.1	2.8	0.0	-0.3	1.3	-1.7
Delta time in closed arm before/after self-admin	0.8	0.8	1.3	0.9	-0.7	1.2	-0.6
Delta time in open arm before/after self-admin	4.4	5.2	7.3	-2.2	1.9	-2.7	2.2
Diff in mean of infusions in LGA sessions	0.4	0.8	2.0	0.8	-0.1	1.4	-0.8
Delay discount exponential model param	1.9	2.5	4.5	-2.1	1.9	-1.2	0.9
Extinction: sum of active levers before priming	1.4	2.1	2.7	1.1	-1.4	1.6	-1.7
Active lever presses in extinction session 6	0.8	0.8	1.9	0.2	-0.1	1.0	-1.4
Bone: final force	0.8	1.3	2.7	0.5	-0.1	1.6	-1.5
Bone: final moment	1.0	1.7	3.4	0.5	-0.1	1.9	-1.7
Food consumed during 24 hour testing period	0.4	0.9	1.8	-1.3	1.3	0.2	-0.4
Glucose	0.2	0.3	0.7	0.9	-0.0	0.6	0.2
Heart weight	0.9	1.4	3.9	-0.6	0.5	1.0	-2.0
Delay discount hyperbolic model param	1.9	2.5	4.6	-2.1	1.8	-1.1	0.9
Intermittent access intake day 1-15 change	0.0	0.1	0.2	-0.4	0.1	0.2	0.5
Intermittent access intake escalation	0.0	0.2	0.5	-0.4	0.3	-0.2	0.7
Intermittent access intake escalation 2	0.3	0.5	0.8	0.6	-0.9	0.9	0.1
Intermitt. access day 1 inactive lever presses	0.0	0.3	0.8	0.4	-0.1	0.9	-0.5
Intermitt. access day 15 inactive lever presses	0.1	0.5	1.4	0.4	-0.2	1.2	-0.5
Intermitt. access escalation Index	0.0	0.1	0.2	0.5	-0.1	0.2	0.4
Intermittent access day 1 total infusions	1.0	2.9	4.1	-1.9	2.0	-1.8	1.0
Intermittent access day 15 total infusions	1.4	3.4	4.0	-1.8	2.0	-1.8	1.8
Intermittent access terminal intake (last 3 days)	1.3	2.3	3.4	-1.7	1.9	-1.3	1.1
Intermittent access total infusions	2.3	2.8	4.1	-1.7	2.0	-1.5	1.2
Intermittent access day 1 locomotion	0.8	1.5	2.5	-1.0	1.3	-1.6	1.0
Intermittent access day 15 total locomotion	0.9	3.5	4.8	-2.2	2.0	-1.9	1.1
Intermittent access total locomotion	2.1	2.5	3.5	-1.9	1.8	-1.7	0.8
Intermittent access standard deviation	0.0	0.2	0.4	-0.6	0.6	0.3	-0.1
Left kidney weight	2.4	19.5	39.8	-6.3	5.8	-1.3	-1.8
Right kidney weight	2.3	16.4	29.8	-5.5	5.2	-0.2	-3.0
Cocaine induced anxiety	0.5	1.5	2.5	0.6	-0.9	1.5	-1.6
Post-drug Anxiety	3.1	3.5	4.4	1.8	-1.9	2.1	-1.6
Baseline Anxiety	0.2	0.3	0.9	0.4	0.0	-0.6	1.0
Tail length	0.3	1.7	4.3	-0.5	0.2	-1.6	2.1
Length with tail	0.5	2.4	3.4	-1.8	1.6	-1.6	1.0
Length without tail	0.2	1.2	2.8	-0.9	0.8	0.7	-1.7
Times rat made contact with spout	0.3	0.3	0.7	-0.5	0.9	-0.5	0.1
Lifetime Intake	2.3	2.8	4.0	-1.8	2.0	-1.6	1.1
Liver weight, left	1.1	2.0	3.3	-1.6	1.8	-1.0	1.1
Liver weight, right	2.4	4.2	5.5	-1.7	2.3	-2.0	2.1
Locomotor activity	1.4	2.1	4.0	-2.0	1.8	-1.2	-0.1
Locomotor testing distance	0.1	0.1	0.2	-0.4	0.3	-0.5	-0.0
Locomotor testing rearing	0.3	1.1	1.6	-1.1	1.3	-1.0	0.7
Locomotion in novel chamber	2.9	4.0	5.6	-1.7	1.5	-2.4	2.2
Locomotion in novel chamber post-restriction	0.0	0.1	0.1	0.3	-0.4	0.1	-0.0
Fecal boli incidents, locomotor time 1	0.0	0.1	0.3	-0.5	0.3	-0.3	-0.2
Change in fecal boli incidents, locomotor task	0.6	0.7	1.1	-0.7	0.6	-0.9	1.0
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.7	-0.0	0.1	0.4	-0.8
Bouts of movement, locomotor time 1	0.6	0.8	2.0	0.4	-0.2	0.9	-1.4
Total resting periods, locomotor time 1	1.7	1.9	3.5	1.1	-0.7	1.6	-1.9
Rest time, locomotor task time 1	0.3	0.5	1.7	-0.4	0.3	0.2	-1.3
Distance moved, locomotor task time 1	0.0	0.0	0.1	-0.1	0.2	-0.1	0.2
Vertical activity count, locomotor time 1	0.1	0.4	0.6	0.8	-0.5	0.7	-0.2
Time >=10cm from walls, locomotor time 2	0.1	0.4	0.8	0.2	-0.7	0.9	-0.4
Bouts of movement, locomotor time 2	0.7	2.2	2.7	1.7	-1.1	1.5	-1.6
Total resting periods, locomotor time 2	0.7	2.7	3.3	1.8	-1.3	1.6	-1.8
Rest time, locomotor task time 2	0.2	0.4	0.5	0.6	-0.7	-0.7	0.2
Distance moved, locomotor task time 2	1.0	1.3	3.0	-1.7	1.4	-0.5	0.5
Vertical activity count, locomotor time 2	0.3	0.7	1.8	-1.3	1.0	-0.0	0.2
Light reinforcement 1	0.6	2.7	4.9	-2.2	1.5	-1.6	1.1
Light reinforcement 2	0.7	1.6	3.9	-2.0	1.5	-0.7	-0.1
Bone: marrow area	0.9	2.2	5.4	-2.3	1.6	-0.8	-0.5
Bone: maximum diameter	1.6	3.2	7.5	-2.7	2.2	-0.4	-0.8
Bone: maximum force	0.7	1.3	2.8	0.1	0.2	1.6	-1.7
Bone: maximum moment	0.9	1.7	3.7	0.1	0.2	1.8	-1.9
Mean time between licks in bursts	0.1	0.3	1.0	0.3	-0.2	-0.4	1.0
Mean num. licks in bursts	0.1	0.4	0.9	-0.3	0.9	0.7	-0.3
Cd content in liver	0.1	0.1	0.3	-0.3	0.6	-0.2	0.1
Co content in liver	0.1	0.1	0.2	-0.4	0.1	-0.5	0.4
Cu content in liver	3.6	4.3	9.9	2.4	-3.2	1.1	-0.7
Fe content in liver	0.6	0.8	1.5	0.1	-0.5	1.1	-1.2
K content in liver	0.0	0.0	0.1	-0.1	-0.3	0.0	0.3
Mg content in liver	0.6	0.6	0.9	0.8	-0.9	0.8	-0.7
Mn content in liver	2.1	2.3	2.9	-1.5	1.7	-1.3	1.5
Na content in liver	0.6	0.7	1.4	1.2	-1.1	0.4	-0.2
Rb content in liver	2.8	3.3	4.1	1.6	-1.7	2.0	-1.9
Se content in liver	0.3	0.3	0.9	-0.2	0.3	-0.5	1.0
Sr content in liver	0.4	0.3	0.6	0.0	0.3	-0.7	0.8
Zn content in liver	0.5	0.5	0.8	-0.4	0.7	-0.9	0.9
Bone: minimum diameter	1.3	2.5	4.7	-2.2	1.7	-1.4	0.8
Time in familiar zone, hab. session 1	0.3	0.4	1.0	-1.0	0.6	-0.1	-0.2
Time in novel zone, hab. session 1	0.1	0.1	0.3	0.5	-0.2	0.2	0.1
Total zone transitions, hab. session 1	0.5	0.7	1.8	1.4	-0.6	0.3	0.7
Total locomotion distance, hab. session 1	0.9	1.3	2.0	-0.7	1.2	-1.2	1.4
Locomotion velocity, hab. session 1	0.9	1.3	1.6	-0.8	1.1	-1.3	1.3
Time in familiar zone, hab. session 2	0.4	0.5	1.1	-0.4	0.4	-0.7	1.0
Time in novel zone, hab. session 2	0.2	0.2	0.3	0.6	-0.5	0.5	-0.4
Total zone transitions, hab. session 2	0.2	0.2	0.6	0.2	0.1	0.8	-0.5
Total locomotion distance, hab. session 2	0.1	0.1	0.3	-0.4	0.5	-0.3	0.1
Locomotion velocity, hab. session 2	0.1	0.1	0.2	-0.3	0.5	-0.2	0.0
Novel to familiar place preference ratio	0.1	0.2	0.4	-0.3	0.3	-0.4	0.6
Novelty place preference	0.6	0.7	1.0	-0.8	0.8	-0.8	1.0
Time in novel zone, NPP test	0.7	0.8	1.2	-0.8	0.9	-0.9	1.1
Total zone transitions, NPP test	0.2	0.2	0.3	0.6	-0.5	0.1	0.5
Total locomotion distance, NPP test	0.2	0.3	0.5	-0.6	0.3	-0.7	0.6
Locomotion velocity, NPP test	0.2	0.3	0.5	-0.5	0.2	-0.7	0.7
Intraocular pressure	0.7	1.1	1.4	-1.1	0.9	-1.2	1.0
Delta distance traveled before/after self-admin	0.3	0.3	1.0	-1.0	0.3	-0.3	0.0
Delta ambulatory time before/after self-admin	0.1	0.1	0.5	-0.7	-0.0	0.0	-0.3
Parametrial fat weight	0.2	0.4	0.8	0.4	-0.3	-0.6	0.9
Pavlov. Cond. lever latency	0.6	0.7	1.5	0.9	-0.4	0.6	-1.2
Pavlov. Cond. magazine entry latency	0.7	1.0	1.8	1.0	-1.3	1.1	-0.0
Pavlov. Cond. change in total contacts	1.2	1.3	1.8	0.9	-1.3	1.4	-0.8
Pavlov. Cond. index score	0.2	0.3	0.6	0.3	-0.8	0.6	0.3
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.0	-0.5	0.3	0.5
Pavlov. Cond. lever contacts	0.4	0.5	1.3	-0.7	0.2	-0.5	1.1
Pavlov. Cond. magazine entry number	0.7	0.9	1.5	-1.0	1.2	-1.0	0.0
Pavlov. Cond. intertrial magazine entries	0.4	0.4	1.0	0.8	-1.0	0.3	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.3	0.7	0.4	-0.8	0.6	0.3
Pavlov. Cond. response bias	0.3	0.4	0.8	0.4	-0.9	0.6	0.2
Pavlov. Cond. lever latency	0.2	0.3	0.9	0.2	0.3	-0.5	0.9
Pavlov. Cond. magazine entry latency	3.0	4.3	4.8	1.9	-2.2	2.1	-2.1
Pavlov. Cond. change in total contacts	1.1	2.7	5.3	0.9	-1.2	1.8	-2.3
Pavlov. Cond. index score	1.1	1.7	2.4	0.9	-1.3	1.4	-1.6
Pavlov. Cond. latency score	1.2	1.9	3.1	0.9	-1.3	1.5	-1.8
Pavlov. Cond. lever contacts	0.4	0.6	1.2	0.1	-0.6	0.9	-1.1
Pavlov. Cond. magazine entry number	1.0	1.3	1.8	-1.0	1.1	-1.1	1.4
Pavlov. Cond. intertrial magazine entries	0.3	0.7	1.3	0.3	-0.1	1.1	-1.1
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.3	2.0	0.8	-1.2	1.1	-1.4
Pavlov. Cond. response bias	1.0	1.4	2.0	0.8	-1.2	1.2	-1.4
Time in closed arm before self-admin	0.4	0.8	1.9	1.0	-1.4	0.3	0.4
Time in closed arm after self-admin	0.2	0.2	0.5	0.4	-0.3	-0.2	0.7
Time in open arm before self-admin	0.1	0.2	0.3	-0.4	0.5	-0.5	0.1
Time in open arm after self-admin	1.1	1.2	1.9	-1.4	1.0	-1.3	0.6
Bone: periosteal estimation	0.9	2.0	4.7	-2.2	1.8	-0.5	-0.4
Bone: periosteal perimeter	1.8	3.6	7.8	-2.8	2.2	-1.3	0.2
Bone: post-yield work	1.6	2.8	3.7	1.8	-1.2	1.9	-1.7
Progressive ratio test 1 active lever presses	0.5	0.9	1.4	-0.7	1.0	-1.2	0.9
Progressive ratio test 1 breakpoint	0.5	0.8	1.3	-0.6	1.0	-1.1	0.9
Progressive ratio test 1 inactive lever presses	0.5	1.3	2.4	-1.0	1.5	-1.0	0.8
Progressive ratio test 2 active lever presses	0.0	0.0	0.1	-0.2	0.3	-0.0	-0.1
Progressive ratio test 2 breakpoint	0.0	0.0	0.1	-0.3	0.3	-0.1	0.0
Progressive ratio test 2 inactive lever presses	0.1	0.3	0.6	-0.4	0.6	-0.4	0.8
Incentive Sensitization - Responses	0.1	0.4	0.6	0.4	-0.4	0.8	-0.7
Incentive Sensitization - Breakpoint	0.2	0.4	0.6	0.3	-0.4	0.8	-0.8
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.4	0.5	-0.6	0.5	-0.6
Progressive ratio	0.1	0.2	0.4	0.6	-0.5	0.4	-0.3
Food seeking constrained by brief footshock	0.1	0.2	0.3	-0.2	0.2	0.6	-0.5
Seeking ratio, punishment vs. effort	0.2	0.5	1.1	0.1	-0.1	1.1	-0.9
Retroperitoneal fat weight	0.4	2.0	4.0	-1.7	0.9	0.7	-2.0
Reaction time number correct	0.1	0.2	0.4	-0.3	0.0	-0.6	0.5
Reaction time mean minus median	0.0	0.2	0.4	0.0	-0.6	-0.4	0.4
Reaction time mean minus median AUC	0.1	0.4	1.0	-0.7	0.1	-1.0	0.4
Reaction time num false alarms	0.9	1.5	2.3	-0.9	0.9	-1.4	1.5
Reaction time num false alarms AUC	1.1	2.5	3.7	-1.1	1.3	-1.8	1.9
Reaction time trials correct on left	0.1	0.2	0.4	-0.3	0.0	-0.6	0.5
Reaction time trials on left	0.1	0.2	0.4	-0.3	-0.0	-0.6	0.6
Reaction time mean	1.0	2.2	4.2	1.7	-2.1	1.2	-0.6
Reaction time mean AUC	0.8	1.9	3.7	1.6	-1.9	1.0	-0.4
Median of all reaction times	2.2	3.4	5.3	2.2	-2.3	1.7	-1.0
Reaction time omissions	0.4	0.6	1.2	1.0	-1.1	0.4	-0.1
Reaction time false alarm rate	0.9	1.3	1.6	-0.8	1.2	-1.2	1.3
Reaction time premature initiation rate	2.0	3.1	5.8	1.1	-1.0	2.1	-2.4
Reaction time premature initiations	0.6	1.9	3.5	0.9	-1.0	1.6	-1.9
Std. dev. reaction times	0.1	0.4	1.2	0.6	-1.1	-0.0	0.3
Reaction time trials completed	0.1	0.2	0.4	-0.3	-0.0	-0.6	0.6
Reaction time trials AUC	0.0	0.1	0.3	-0.4	0.0	-0.5	0.4
Run reversals in cocaine runway, females	0.4	0.4	1.1	-0.0	0.0	-0.7	1.1
Run reversals in cocaine runway, males	2.5	2.7	3.6	-1.9	1.6	-1.9	1.1
Latency to leave start box in cocaine runway	0.6	0.8	1.9	-1.1	1.4	-0.3	0.1
Latency to leave start box in cocaine runway, F	0.4	0.5	1.4	-0.8	1.2	-0.0	-0.2
Latency to leave start box in cocaine runway, M	0.4	0.4	0.6	-0.8	0.6	-0.5	0.4
Std. dev. time between licks in bursts	0.5	1.0	1.8	0.4	-0.9	1.1	-1.3
Total sessions with >9 infusions	2.0	2.5	4.2	-2.0	2.1	-1.3	0.3
Short access day 1 total inactive lever presses	0.3	0.6	1.1	-1.1	0.6	0.3	-1.0
Short access day 10 total inactive lever presses	0.0	0.2	0.4	-0.6	0.2	0.1	-0.5
Short access day 1 total infusions	0.8	1.5	2.6	-1.4	1.6	-1.1	0.6
Short access day 10 total infusions	1.0	1.6	3.3	-1.4	1.8	-0.9	0.5
Short access total infusions	1.0	1.5	2.6	-1.5	1.6	-0.9	0.2
Short access day 1 locomotion	0.1	0.2	0.4	-0.3	0.6	-0.3	0.3
Short access day 10 total locomotion	0.6	2.4	3.3	-1.0	1.8	-1.8	1.5
Short access total locomotion	0.6	0.9	1.3	-0.9	1.1	-1.0	0.8
One hour access (0.3 mA shock)	1.3	1.6	2.1	-1.4	1.4	-1.1	1.1
Compulsive drug intake	0.3	0.5	0.9	0.3	-0.6	0.7	-0.9
One hour access (shock baseline)	1.0	2.6	3.2	-1.5	1.8	-1.5	1.7
Social response proportion	0.3	0.4	0.9	-1.0	0.9	-0.1	-0.1
Social responses	1.5	2.0	3.4	-1.9	1.5	-1.2	0.9
Social time	0.2	0.3	0.9	0.3	-0.1	-0.3	1.0
Soleus weight	0.4	1.2	2.2	0.7	-0.4	1.4	-1.5
Bone: stiffness	1.9	3.5	5.5	1.7	-1.2	2.3	-2.1
Tibialis anterior weight	0.1	0.5	0.8	0.6	-0.7	0.5	-0.9
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	0.1	0.5	-0.2	-0.0
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.1	-0.2	0.0	-0.2	0.1
Time to tail flick, test, before self-admin	1.0	1.2	2.4	-1.1	1.5	-0.8	0.7
Time to tail flick, test, after self-admin	0.5	0.5	0.9	0.7	-0.6	1.0	-0.6
Delta time to tail flick, vehicle, before/after SA	0.5	0.5	1.5	-0.2	-0.3	0.7	-1.2
Delta time to tail flick, test, before/after SA	1.5	1.9	3.3	1.5	-1.8	1.2	-0.7
Tibia length	0.0	0.1	0.1	-0.2	-0.3	0.3	-0.2
Ambulatory time before self-admin	0.7	2.1	3.2	-1.0	1.3	-1.6	1.8
Ambulatory time after self-admin	0.2	0.3	0.8	-0.4	-0.1	-0.4	0.9
Bone: tissue strength	1.9	2.0	2.3	1.2	-1.5	1.5	-1.3
Total heroin consumption	0.9	1.0	2.0	0.4	-0.6	1.4	-1.3
Bone: trabecular number	0.2	0.4	0.9	0.8	-0.9	-0.1	0.5
Bone: trabecular spacing	1.1	1.6	3.1	-1.8	1.3	-0.2	-1.2
Bone: trabecular thickness	0.1	0.1	0.4	0.2	0.1	-0.3	0.6
Bone: trabecular tissue density	0.6	1.1	2.1	1.4	-1.3	0.6	-0.4
Water consumed over 24 hours	0.2	0.3	0.7	-0.9	0.7	-0.1	-0.2
Number of responses in last shaping day	0.2	0.3	0.7	0.9	-0.3	0.6	-0.3