Hub : Genes

LOC120093526

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability LOC120093526 0.03 0.03 1.6e-03 0.01 0.01 0.01 0.01 1.9e-02 1.1e-02 3.8e-02 2.1e-02
2 NAcc gene expression LOC120093526 0.03 0.03 8.9e-04 0.02 0.02 0.02 0.02 1.1e-03 1.2e-03 6.6e-04 2.8e-04
3 Adipose isoform ratio XR_010053543.1 0.04 0.03 8.2e-05 0.03 0.03 0.03 0.03 1.4e-04 4.7e-04 8.2e-04 4.6e-04
4 Brain gene expression LOC120093526 0.06 0.04 1.6e-05 0.03 0.04 0.04 0.04 6.7e-04 1.3e-04 2.0e-04 9.3e-05
5 Adipose isoform ratio XR_010053542.1 0.05 0.03 1.6e-04 0.03 0.03 0.02 0.03 2.6e-04 4.2e-04 9.1e-04 6.8e-04
6 PL alternative TSS XR_010053543.1 0.02 0.02 5.3e-03 0.01 0.01 0.01 0.01 5.8e-02 8.3e-03 1.5e-02 2.3e-02
7 Adipose gene expression LOC120093526 0.03 0.02 3.7e-03 0.01 0.02 0.02 0.02 4.5e-02 2.6e-03 4.3e-03 6.4e-03
8 PL gene expression LOC120093526 0.04 0.03 4.7e-03 -0 0.01 0.01 0.01 5.1e-01 1.0e-02 1.7e-02 5.2e-02
9 PL isoform ratio XR_010053542.1 0.04 0.04 7.9e-03 0.02 0.02 0.01 0.01 3.5e-03 4.5e-03 7.3e-03 1.9e-02
10 Adipose isoform ratio XR_010053544.1 0.05 0.04 1.4e-04 0.04 0.03 0.03 0.03 4.8e-05 3.9e-04 5.6e-04 4.9e-04
11 Eye alternative TSS XR_005486764.2 0.46 0.22 7.6e-03 0.1 0.09 0.1 0.08 1.2e-02 2.0e-02 1.5e-02 2.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.62.96.40.20.2-0.80.9-1.0-1.7-1.82.4-2.52.52.4
Area under the delay curve0.00.00.20.20.10.40.1-0.10.0-0.00.2-0.00.20.3
BMI with tail4.917.132.05.75.55.45.3-5.34.03.92.41.1-1.1-1.1
BMI without tail0.84.17.52.72.72.72.5-2.62.12.01.00.7-0.7-0.7
Body weight0.93.78.22.42.42.91.9-2.02.22.20.41.1-1.1-1.1
Weight adjusted by age0.00.10.2-0.2-0.20.0-0.40.40.10.1-0.4-0.1-0.3-0.2
Bone surface3.46.713.9-0.4-0.3-1.90.8-0.9-3.0-3.13.2-3.63.73.6
Bone volume3.36.614.1-0.1-0.0-1.61.1-1.2-2.8-2.93.4-3.63.73.6
Breakpoint value in progressive ratio session0.40.71.4-1.2-1.0-1.0-1.01.1-0.7-0.6-0.70.60.1-0.2
Number of licking bursts0.92.85.32.01.82.31.5-1.62.12.1-0.01.0-1.4-1.2
Context. condit. distance diff. score0.20.20.40.60.50.60.5-0.60.50.50.20.0-0.2-0.2
Locomotion velocity, session 10.91.02.40.30.3-0.00.6-0.5-0.9-0.91.5-1.61.41.4
Locomotion distance, session 11.31.73.5-0.4-0.4-1.00.1-0.1-1.6-1.61.4-1.91.81.8
Locomotion velocity, session 22.42.95.1-1.2-1.3-1.8-0.70.6-2.3-2.31.2-2.12.12.1
Locomotion distance, session 23.04.27.2-2.0-2.0-2.2-1.51.5-2.7-2.70.7-2.22.12.1
Locomotion velocity, session 32.83.26.2-2.5-2.4-2.1-2.42.5-1.6-1.5-1.3-0.40.20.2
Locomotion distance, session 30.10.10.2-0.3-0.2-0.0-0.40.40.00.0-0.4-0.0-0.2-0.2
Stereotopy head waving bouts, day 33.74.47.7-2.8-2.7-2.8-2.42.5-2.3-2.2-0.7-0.91.01.0
Stereotopy head waving duration, day 32.53.16.6-2.3-2.3-2.6-1.91.9-1.9-1.8-0.6-0.70.80.8
Locomotion velocity, session 70.20.20.6-0.2-0.3-0.4-0.10.0-0.6-0.60.4-0.80.60.6
Locomotion distance, session 70.30.40.90.30.20.60.0-0.10.90.9-0.70.7-0.9-0.9
Stereotopy head waving bouts, day 71.21.42.6-1.0-0.9-1.2-0.60.7-1.6-1.60.7-1.31.41.4
Stereotopy head waving duration, day 71.41.73.1-0.9-0.8-1.2-0.40.6-1.7-1.81.0-1.51.71.7
Locomotion velocity, session 82.22.74.5-1.2-1.3-1.5-0.80.8-2.1-2.11.1-2.12.02.0
Locomotion distance, session 80.40.50.9-0.7-0.9-0.7-0.60.6-0.9-0.90.2-0.90.70.7
Degree of sensitization distance0.30.40.80.90.80.70.9-0.90.50.50.50.1-0.0-0.0
Degree of sensitization stereotypy0.40.41.00.30.30.00.5-0.4-0.5-0.61.0-0.81.01.0
Conditioned locomotion1.51.83.21.01.11.50.5-0.41.81.8-0.91.5-1.7-1.5
Cocaine response after cond. corrected1.62.44.31.61.51.91.3-1.12.12.1-0.41.2-1.7-1.4
Cocaine response after cond. not corrected1.92.84.91.71.62.01.3-1.12.22.2-0.61.4-1.8-1.7
Cocaine response before conditioning0.30.40.7-0.8-0.5-0.9-0.70.7-0.8-0.7-0.10.00.60.2
Saline control response0.60.81.60.91.01.30.5-0.51.11.1-0.31.1-0.9-0.9
Bone: connectivity density1.01.63.90.10.1-0.70.6-0.6-1.3-1.31.7-2.01.81.7
Bone: cortical apparent density0.60.92.21.31.20.91.4-1.50.80.70.80.1-0.0-0.0
Bone: cortical area1.21.94.81.01.10.11.6-1.7-0.7-0.72.2-1.61.61.6
Bone: cortical porosity0.30.30.90.00.0-0.30.3-0.4-0.5-0.50.7-0.90.80.7
Bone: cortical porosity0.70.81.70.30.3-0.30.7-0.9-0.7-0.71.3-1.31.21.1
Bone: cortical thickness1.11.84.51.61.70.81.9-2.10.20.11.9-0.80.90.9
Bone: cortical thickness0.60.71.21.01.01.00.7-0.81.11.1-0.10.8-0.7-0.7
Bone: cortical tissue density0.40.61.51.11.00.71.2-1.20.60.60.70.1-0.00.0
Condit. Reinf. active minus inactive responses1.31.53.0-1.6-1.7-1.6-1.51.4-1.2-1.2-0.5-0.80.40.4
Condit. Reinf. active-inactive response ratio0.20.30.5-0.6-0.6-0.5-0.60.60.00.1-0.70.3-0.5-0.5
Condit. Reinf. active responses2.32.94.8-2.0-2.1-2.2-1.71.5-2.1-2.0-0.0-1.61.31.3
Condit. Reinf. inactive responses1.72.23.7-1.4-1.4-1.6-1.11.0-1.9-1.90.6-1.71.61.6
Incentive salience index mean1.31.62.5-1.3-1.5-1.5-1.00.9-1.6-1.60.3-1.51.11.1
Condit. Reinf. lever presses1.31.94.8-0.5-0.8-0.8-0.10.2-1.7-1.81.4-2.21.91.9
Condit. Reinf. active minus inactive responses1.32.04.0-1.9-1.7-1.5-2.02.0-0.4-0.4-1.90.8-0.8-0.8
Condit. Reinf. active-inactive response ratio1.11.74.3-0.9-0.8-0.3-1.31.40.70.8-2.11.5-1.6-1.7
Condit. Reinf. active responses1.01.42.9-1.7-1.5-1.6-1.61.6-1.0-0.9-1.0-0.10.00.0
Condit. Reinf. inactive responses0.40.61.0-0.7-0.6-1.0-0.50.4-1.0-1.00.3-0.80.80.8
Condit. Reinf. lever presses1.52.24.4-2.0-1.9-1.7-2.12.1-0.8-0.7-1.61.0-0.5-0.4
Condit. Reinf. lever reinforcers received0.81.12.2-1.5-1.3-1.3-1.51.5-0.6-0.5-1.20.3-0.3-0.3
Conditioned reinforcement - actives0.00.10.4-0.10.1-0.50.5-0.3-0.00.00.0-0.6-0.1-0.0
Conditioned reinforcement - inactives0.20.50.90.50.70.30.7-0.70.91.0-0.40.4-0.8-0.9
Conditioned locomotion1.42.16.5-1.8-1.6-2.6-1.01.1-1.7-1.6-0.2-1.10.80.9
Patch foraging indifference point 0 sec1.33.78.22.62.72.12.9-2.91.21.21.9-0.20.30.2
Patch foraging indifference point AUC0.30.61.5-1.0-1.2-0.8-1.21.2-0.5-0.4-0.8-0.0-0.2-0.0
Delay disc. indifference point, 0s delay1.92.14.91.41.00.91.7-1.7-0.4-0.52.2-1.81.51.7
Delay disc. indifference point, 16s delay0.10.10.2-0.4-0.3-0.3-0.40.4-0.4-0.40.00.00.30.5
Delay disc. indifference point, 2s delay0.40.41.10.60.20.60.7-0.7-0.2-0.31.0-0.20.80.9
Delay disc. indifference point, 24s delay0.10.20.70.60.50.80.5-0.40.40.30.30.1-0.00.1
Delay disc. indifference point, 4s delay0.70.71.4-0.5-0.6-0.7-0.20.2-1.1-1.10.7-1.01.11.2
Delay disc. indifference point, 8s delay0.20.30.70.40.30.80.1-0.10.80.8-0.50.4-0.8-0.7
Indifference point function ln k0.00.10.30.30.50.10.4-0.50.30.30.10.3-0.1-0.2
Indifference point function log k0.00.10.30.30.50.10.4-0.50.30.30.10.3-0.1-0.2
Patch foraging total patch changes 0 sec1.13.37.42.42.51.92.7-2.71.21.11.7-0.10.30.1
Patch foraging total patch changes 12 sec1.21.73.11.61.61.81.4-1.41.51.50.30.7-0.8-0.6
Patch foraging total patch changes 18 sec0.00.00.10.20.10.30.2-0.2-0.0-0.10.3-0.10.30.2
Patch foraging total patch changes 24 sec0.10.40.90.80.80.70.9-0.90.10.10.90.10.50.4
Patch foraging total patch changes 6 sec1.01.73.71.81.91.31.8-1.90.80.81.2-0.40.10.2
Patch foraging time to switch 0 sec0.20.61.30.70.70.30.9-0.8-0.2-0.31.1-1.10.80.9
Patch foraging water rate 0 sec0.31.11.80.80.81.20.5-0.61.31.4-0.61.3-1.2-1.3
Patch foraging water rate 12 sec0.41.42.31.01.11.20.8-0.81.51.5-0.51.5-1.2-1.5
Patch foraging water rate 18 sec1.43.18.40.00.01.0-0.70.61.81.9-2.22.9-2.3-2.6
Patch foraging water rate 24 sec3.75.29.11.41.42.40.5-0.62.93.0-1.83.0-2.8-3.0
Patch foraging water rate 6 sec1.11.63.9-0.8-0.6-0.2-1.11.00.80.8-1.92.0-1.5-1.9
Seeking ratio, delayed vs. immediate footshock0.91.33.1-1.4-1.2-1.8-0.80.8-1.5-1.50.10.21.00.9
Distance traveled before self-admin0.51.02.0-1.4-1.3-1.2-1.31.3-1.0-1.0-0.60.00.40.2
Distance traveled after self-admin0.00.00.1-0.00.10.1-0.10.30.0-0.0-0.10.2-0.00.0
Extensor digitorum longus weight3.514.225.34.84.75.04.1-4.24.34.20.92.1-2.2-2.1
Bone: elastic displacement0.00.00.00.00.1-0.00.1-0.1-0.1-0.10.2-0.00.10.2
Bone: elastic work0.60.81.71.11.10.71.2-1.30.10.11.3-0.40.60.7
Bone: endosteal estimation0.40.92.01.01.00.41.4-1.4-0.0-0.01.3-0.80.80.8
Bone: endosteal perimeter0.51.32.3-0.8-0.8-1.3-0.30.2-1.5-1.50.8-1.41.41.4
Epididymis fat weight0.20.82.0-0.4-0.50.2-0.70.60.70.8-1.41.3-1.2-1.3
Delta time in closed arm before/after self-admin3.43.27.81.11.21.50.6-0.72.22.3-1.42.8-2.2-2.2
Delta time in open arm before/after self-admin0.50.61.61.01.11.30.8-0.70.70.70.4-0.1-0.2-0.2
Diff in mean of infusions in LGA sessions0.71.32.8-1.7-1.5-1.5-1.41.6-0.9-0.9-1.0-0.10.00.0
Delay discount exponential model param0.00.00.1-0.10.1-0.30.0-0.00.00.1-0.1-0.0-0.2-0.3
Extinction: sum of active levers before priming0.81.22.5-1.4-1.4-0.9-1.41.5-0.2-0.1-1.60.7-0.8-0.8
Active lever presses in extinction session 60.20.20.6-0.4-0.6-0.5-0.30.3-0.6-0.60.1-0.80.50.4
Bone: final force2.13.57.02.22.31.22.6-2.60.10.02.6-1.51.41.4
Bone: final moment2.13.47.02.12.31.22.6-2.60.10.02.6-1.41.41.4
Food consumed during 24 hour testing period0.10.30.50.70.70.70.6-0.70.40.40.40.2-0.10.1
Glucose0.91.42.81.61.51.71.4-1.41.21.10.60.3-0.4-0.4
Heart weight0.30.41.1-0.7-0.7-0.4-0.80.80.20.2-1.00.7-0.7-0.6
Delay discount hyperbolic model param0.10.10.3-0.4-0.2-0.5-0.40.40.00.1-0.50.1-0.4-0.5
Intermittent access intake day 1-15 change0.10.71.4-0.9-0.7-0.7-0.91.00.10.1-1.21.1-0.7-0.9
Intermittent access intake escalation0.10.71.4-0.8-0.6-0.6-0.90.90.10.2-1.21.1-0.7-0.9
Intermittent access intake escalation 20.40.71.5-1.0-1.0-0.8-1.11.2-0.3-0.2-0.90.8-0.3-0.5
Intermitt. access day 1 inactive lever presses0.11.43.7-0.7-0.8-0.0-1.31.10.80.9-1.91.1-1.5-1.5
Intermitt. access day 15 inactive lever presses0.10.71.6-1.1-1.3-0.6-1.21.1-0.4-0.3-1.0-0.1-0.2-0.5
Intermitt. access escalation Index0.10.41.00.20.2-0.20.4-0.4-0.6-0.61.0-0.70.90.9
Intermittent access day 1 total infusions0.10.20.40.40.30.20.7-0.40.50.5-0.00.0-0.4-0.2
Intermittent access day 15 total infusions0.00.00.2-0.1-0.1-0.50.4-0.2-0.1-0.00.00.00.0-0.1
Intermittent access terminal intake (last 3 days)0.10.20.6-0.3-0.2-0.80.4-0.2-0.6-0.60.5-0.60.60.4
Intermittent access total infusions0.10.10.60.20.3-0.20.8-0.60.00.00.4-0.50.10.1
Intermittent access day 1 locomotion0.20.31.00.20.30.30.10.10.80.8-0.70.4-1.0-0.7
Intermittent access day 15 total locomotion0.10.30.7-0.6-0.4-0.7-0.30.50.10.2-0.80.4-0.5-0.7
Intermittent access total locomotion0.10.10.3-0.4-0.3-0.5-0.10.30.00.1-0.50.2-0.4-0.4
Intermittent access standard deviation0.20.92.7-1.1-0.9-1.6-0.80.8-1.1-1.0-0.0-0.80.60.5
Left kidney weight0.00.10.20.10.00.4-0.20.30.40.4-0.40.4-0.5-0.4
Right kidney weight0.10.51.3-0.8-0.8-0.3-1.11.10.00.1-1.10.6-0.7-0.3
Cocaine induced anxiety0.72.03.8-1.4-1.5-1.7-0.90.9-2.0-2.00.6-0.71.61.5
Post-drug Anxiety1.82.14.6-0.9-1.0-1.5-0.20.2-2.1-2.11.4-0.42.21.8
Baseline Anxiety0.00.00.20.10.10.10.2-0.20.00.00.20.40.1-0.0
Tail length1.58.017.0-3.9-3.7-3.4-4.13.9-2.2-2.1-2.4-0.0-0.00.1
Length with tail0.93.89.1-2.7-2.4-1.9-3.02.8-1.0-0.9-2.20.6-0.6-0.6
Length without tail0.10.81.40.91.01.20.6-0.61.11.1-0.20.8-0.8-0.7
Times rat made contact with spout1.01.12.31.21.21.50.8-0.91.41.4-0.20.5-0.9-1.0
Lifetime Intake0.50.62.20.80.90.11.5-1.30.20.20.8-0.50.30.1
Liver weight, left0.30.40.90.90.81.00.7-0.80.70.70.20.3-0.4-0.3
Liver weight, right0.20.30.7-0.4-0.40.2-0.80.70.20.2-0.80.6-0.6-0.5
Locomotor activity2.33.65.6-2.3-2.2-2.4-2.02.0-2.3-2.2-0.2-1.11.41.3
Locomotor testing distance0.81.83.3-1.6-1.5-1.8-1.31.3-1.7-1.7-0.0-0.71.11.1
Locomotor testing rearing0.00.10.2-0.10.10.2-0.30.30.30.3-0.50.5-0.4-0.4
Locomotion in novel chamber0.00.00.10.20.3-0.00.3-0.20.10.10.20.20.00.0
Locomotion in novel chamber post-restriction1.23.77.2-2.6-2.7-2.3-2.72.6-1.7-1.7-1.20.60.40.4
Fecal boli incidents, locomotor time 10.41.12.01.01.11.40.6-0.51.31.3-0.41.2-1.0-1.0
Change in fecal boli incidents, locomotor task1.31.42.3-0.7-0.8-1.2-0.40.3-1.5-1.50.9-1.51.51.5
Time >=10cm from walls, locomotor time 10.81.02.20.70.80.21.1-1.0-0.5-0.51.5-1.51.21.2
Bouts of movement, locomotor time 10.40.50.9-1.0-0.9-0.8-0.90.9-0.4-0.4-0.7-0.3-0.2-0.2
Total resting periods, locomotor time 10.80.91.9-1.4-1.3-1.2-1.31.3-0.8-0.8-0.8-0.30.00.0
Rest time, locomotor task time 10.40.60.9-0.8-0.8-0.9-0.70.7-1.0-1.00.1-0.70.70.7
Distance moved, locomotor task time 10.41.22.80.90.90.31.4-1.3-0.4-0.41.7-1.41.21.2
Vertical activity count, locomotor time 10.10.91.91.21.21.01.4-1.30.90.90.50.1-0.3-0.3
Time >=10cm from walls, locomotor time 20.31.01.41.11.11.21.0-1.01.21.2-0.01.0-0.8-0.8
Bouts of movement, locomotor time 20.30.93.3-0.4-0.3-0.8-0.20.1-1.1-1.10.7-1.81.11.1
Total resting periods, locomotor time 20.31.14.2-0.4-0.2-0.9-0.2-0.0-1.2-1.20.9-2.01.31.3
Rest time, locomotor task time 20.30.51.0-0.2-0.2-0.5-0.00.0-0.9-0.90.7-1.01.01.0
Distance moved, locomotor task time 20.20.30.70.10.20.3-0.00.10.70.7-0.70.5-0.9-0.9
Vertical activity count, locomotor time 20.71.63.01.21.11.60.8-0.81.71.7-0.61.1-1.4-1.4
Light reinforcement 10.94.27.9-2.8-2.5-2.8-2.32.2-2.3-2.3-0.7-0.91.20.7
Light reinforcement 20.40.91.8-1.3-1.1-1.3-1.21.0-1.0-1.0-0.4-0.40.50.2
Bone: marrow area0.30.81.80.90.90.41.3-1.3-0.0-0.11.3-0.70.70.7
Bone: maximum diameter0.91.93.3-0.9-0.8-1.6-0.30.1-1.8-1.81.1-1.61.71.7
Bone: maximum force1.73.37.12.22.41.42.6-2.70.40.32.4-1.11.11.2
Bone: maximum moment1.83.37.12.32.41.42.6-2.70.40.32.4-1.11.11.2
Mean time between licks in bursts0.10.71.5-1.1-1.2-1.2-1.01.0-0.5-0.5-0.80.3-0.30.1
Mean num. licks in bursts0.20.50.9-0.9-0.7-0.9-0.70.8-0.8-0.8-0.1-0.50.60.3
Cd content in liver0.20.20.7-0.6-0.9-0.8-0.30.3-0.5-0.5-0.1-0.10.10.2
Co content in liver1.61.94.0-1.9-2.0-1.5-2.02.0-0.8-0.7-1.50.4-0.4-0.4
Cu content in liver0.81.02.30.50.5-0.30.9-1.1-0.7-0.71.5-1.41.31.2
Fe content in liver0.20.20.40.50.50.40.4-0.40.60.6-0.10.1-0.5-0.5
K content in liver0.90.91.6-0.9-0.8-1.3-0.60.6-1.3-1.30.4-1.01.01.0
Mg content in liver0.91.01.5-1.2-1.2-1.2-1.11.0-1.2-1.2-0.0-0.80.80.8
Mn content in liver3.64.17.5-1.3-1.2-2.0-0.50.6-2.6-2.61.6-2.72.62.5
Na content in liver0.30.40.90.30.40.10.5-0.4-0.4-0.50.9-0.90.90.7
Rb content in liver0.81.02.30.40.3-0.30.6-0.9-0.8-0.81.5-1.21.41.5
Se content in liver0.00.00.1-0.1-0.1-0.1-0.00.1-0.1-0.1-0.0-0.4-0.00.0
Sr content in liver0.30.30.6-0.4-0.4-0.5-0.40.40.20.3-0.80.7-0.7-0.7
Zn content in liver2.63.06.4-1.9-1.8-1.1-2.52.20.10.2-2.51.4-1.6-1.6
Bone: minimum diameter0.50.92.20.50.4-0.31.0-1.1-0.7-0.71.5-1.21.21.2
Time in familiar zone, hab. session 12.52.86.1-2.3-2.2-1.7-2.42.5-1.1-1.0-1.70.3-0.3-0.3
Time in novel zone, hab. session 12.22.55.31.91.81.12.3-2.30.30.22.2-1.21.11.1
Total zone transitions, hab. session 11.11.63.0-0.7-0.8-1.1-0.30.3-1.6-1.61.1-1.71.71.7
Total locomotion distance, hab. session 13.14.47.5-1.5-1.6-2.2-0.90.9-2.7-2.71.4-2.72.52.5
Locomotion velocity, hab. session 12.53.66.1-1.6-1.7-2.2-1.11.1-2.5-2.50.9-2.22.12.1
Time in familiar zone, hab. session 22.93.37.1-2.4-2.4-1.8-2.72.6-0.8-0.7-2.20.9-0.8-0.8
Time in novel zone, hab. session 23.43.77.92.52.41.82.8-2.80.60.52.4-1.11.01.0
Total zone transitions, hab. session 21.72.14.90.80.80.21.3-1.3-1.0-1.12.2-2.11.91.9
Total locomotion distance, hab. session 20.91.22.6-0.6-0.6-0.8-0.30.3-1.4-1.40.9-1.61.41.4
Locomotion velocity, hab. session 21.31.83.9-0.7-0.7-0.9-0.30.3-1.7-1.71.2-2.01.81.8
Novel to familiar place preference ratio1.92.45.11.81.81.22.1-2.10.1-0.02.3-1.21.31.3
Novelty place preference1.41.83.91.41.40.81.7-1.8-0.1-0.22.0-1.21.31.3
Time in novel zone, NPP test1.72.04.11.71.61.02.0-2.00.10.02.0-1.11.21.2
Total zone transitions, NPP test0.50.81.80.70.70.60.9-0.9-0.3-0.41.3-1.21.01.0
Total locomotion distance, NPP test0.70.92.50.20.1-0.10.5-0.5-0.9-1.01.3-1.61.41.4
Locomotion velocity, NPP test0.60.92.4-0.1-0.2-0.40.1-0.1-1.1-1.11.1-1.51.31.3
Intraocular pressure0.91.43.4-0.5-0.60.5-1.01.10.90.9-1.71.8-1.4-1.6
Delta distance traveled before/after self-admin0.40.50.90.90.90.90.7-0.60.80.80.20.4-0.4-0.2
Delta ambulatory time before/after self-admin0.20.40.90.90.90.70.9-0.80.40.30.7-0.20.10.4
Parametrial fat weight0.30.61.41.01.10.71.2-1.10.40.40.9-0.30.20.3
Pavlov. Cond. lever latency1.01.22.70.20.50.5-0.20.21.31.3-1.31.7-1.6-1.6
Pavlov. Cond. magazine entry latency0.91.22.9-1.5-1.7-1.2-1.41.3-1.0-0.9-0.7-0.40.20.2
Pavlov. Cond. change in total contacts0.10.10.40.40.10.40.4-0.60.10.10.4-0.30.20.2
Pavlov. Cond. index score0.60.71.2-0.7-1.0-0.7-0.50.5-1.1-1.10.4-1.00.90.9
Pavlov. Cond. latency score0.91.12.0-0.8-1.1-0.9-0.40.4-1.4-1.40.7-1.41.31.3
Pavlov. Cond. lever contacts0.81.02.50.0-0.3-0.20.4-0.4-1.0-1.11.3-1.61.41.4
Pavlov. Cond. magazine entry number0.40.51.40.91.20.61.0-0.90.50.50.60.1-0.00.0
Pavlov. Cond. intertrial magazine entries0.40.51.1-0.2-0.10.1-0.50.40.60.7-1.11.1-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.2-0.8-1.1-0.8-0.60.6-1.1-1.10.2-1.00.80.8
Pavlov. Cond. response bias0.30.41.2-0.8-1.1-0.5-0.80.8-0.6-0.6-0.4-0.30.20.2
Pavlov. Cond. lever latency0.91.32.51.61.51.31.6-1.51.01.00.8-0.5-0.2-0.3
Pavlov. Cond. magazine entry latency1.21.83.3-1.8-1.8-1.6-1.81.6-1.3-1.3-0.7-0.20.40.4
Pavlov. Cond. change in total contacts0.30.61.3-1.1-1.0-1.0-1.11.1-0.5-0.5-0.80.4-0.1-0.1
Pavlov. Cond. index score1.01.63.1-1.8-1.7-1.6-1.71.6-1.1-1.0-1.00.40.10.1
Pavlov. Cond. latency score1.11.83.4-1.8-1.8-1.6-1.81.7-1.3-1.3-0.80.10.40.4
Pavlov. Cond. lever contacts0.91.32.7-1.5-1.5-1.2-1.61.5-0.8-0.8-1.00.8-0.1-0.0
Pavlov. Cond. magazine entry number1.51.93.51.91.81.81.8-1.61.41.40.70.1-0.5-0.5
Pavlov. Cond. intertrial magazine entries0.51.21.91.21.41.41.0-1.01.31.3-0.00.9-0.8-0.9
Pavlov. Cond. lever-magazine prob. diff.1.21.83.5-1.9-1.8-1.8-1.81.6-1.3-1.2-0.80.20.30.3
Pavlov. Cond. response bias1.42.04.1-1.9-1.9-1.6-2.01.9-0.9-0.9-1.30.9-0.2-0.1
Time in closed arm before self-admin0.30.51.40.30.3-0.20.4-0.5-0.7-0.71.2-0.81.11.1
Time in closed arm after self-admin0.40.52.30.60.80.30.6-0.80.60.60.21.5-0.3-0.4
Time in open arm before self-admin0.00.00.3-0.1-0.1-0.30.1-0.00.00.1-0.1-0.5-0.1-0.1
Time in open arm after self-admin1.21.32.81.41.51.71.2-1.01.31.30.2-0.4-0.7-0.7
Bone: periosteal estimation1.02.35.51.21.20.21.9-2.0-0.6-0.72.3-1.61.71.7
Bone: periosteal perimeter0.81.53.0-0.1-0.1-0.80.5-0.7-1.4-1.41.6-1.71.71.7
Bone: post-yield work0.20.40.90.90.90.70.9-0.90.50.40.50.10.00.1
Progressive ratio test 1 active lever presses0.20.30.80.70.60.40.9-0.80.60.60.1-0.0-0.4-0.3
Progressive ratio test 1 breakpoint0.20.30.80.70.60.50.9-0.80.60.70.1-0.0-0.4-0.3
Progressive ratio test 1 inactive lever presses0.10.20.7-0.6-0.6-0.8-0.20.2-0.4-0.3-0.2-0.20.00.0
Progressive ratio test 2 active lever presses0.10.10.4-0.3-0.3-0.50.20.0-0.2-0.2-0.1-0.60.1-0.0
Progressive ratio test 2 breakpoint0.10.10.5-0.4-0.4-0.60.10.2-0.3-0.3-0.1-0.70.10.0
Progressive ratio test 2 inactive lever presses0.10.41.00.20.3-0.30.9-0.7-0.3-0.30.7-1.00.60.4
Incentive Sensitization - Responses0.10.30.5-0.7-0.7-0.5-0.50.7-0.4-0.3-0.5-0.5-0.0-0.1
Incentive Sensitization - Breakpoint0.20.40.7-0.8-0.8-0.7-0.60.8-0.6-0.6-0.4-0.70.20.1
Sum of active levers in priming session hrs 5-60.10.10.5-0.4-0.4-0.2-0.30.4-0.1-0.1-0.40.7-0.1-0.2
Progressive ratio0.41.12.11.31.41.21.1-1.01.31.30.1-0.2-0.8-0.8
Food seeking constrained by brief footshock1.11.43.3-1.5-1.7-1.0-1.81.8-0.8-0.8-1.00.10.0-0.1
Seeking ratio, punishment vs. effort1.02.14.4-1.9-2.1-1.5-2.02.0-1.3-1.3-0.90.70.40.4
Retroperitoneal fat weight1.67.212.03.23.33.52.6-2.53.33.30.12.0-2.0-2.1
Reaction time number correct0.41.52.71.21.11.60.7-0.61.61.6-0.51.3-1.3-1.3
Reaction time mean minus median0.21.22.3-1.4-1.5-1.4-1.41.4-1.1-1.1-0.40.10.40.5
Reaction time mean minus median AUC0.42.54.4-1.4-1.6-1.8-1.01.1-2.1-2.10.8-1.31.71.8
Reaction time num false alarms0.40.61.51.01.21.20.8-0.90.90.90.2-0.0-0.4-0.4
Reaction time num false alarms AUC0.40.81.71.01.21.30.7-0.81.11.1-0.00.4-0.7-0.7
Reaction time trials correct on left0.41.52.71.21.11.60.7-0.61.61.6-0.51.3-1.3-1.3
Reaction time trials on left0.41.42.51.11.11.60.7-0.61.61.5-0.41.2-1.2-1.2
Reaction time mean0.71.72.8-1.3-1.6-1.6-0.91.0-1.7-1.70.4-0.71.21.4
Reaction time mean AUC0.41.01.9-0.8-1.1-1.2-0.40.6-1.4-1.40.6-0.61.11.3
Median of all reaction times0.81.22.1-0.9-1.3-1.3-0.50.7-1.4-1.40.6-0.81.21.3
Reaction time omissions0.20.41.0-0.0-0.1-0.50.3-0.2-0.7-0.70.8-0.30.81.0
Reaction time false alarm rate0.10.20.40.50.60.40.4-0.60.10.10.5-0.40.20.2
Reaction time premature initiation rate0.91.33.4-1.4-1.2-0.8-1.61.8-0.1-0.0-1.70.7-0.9-1.0
Reaction time premature initiations0.51.64.0-0.7-0.60.1-1.21.50.80.9-2.01.5-1.6-1.7
Std. dev. reaction times0.31.01.7-1.0-1.3-1.3-0.80.9-1.3-1.30.2-0.60.91.0
Reaction time trials completed0.41.42.51.11.11.60.7-0.61.61.5-0.41.2-1.2-1.2
Reaction time trials AUC0.51.83.21.21.21.80.8-0.61.81.8-0.61.4-1.4-1.5
Run reversals in cocaine runway, females2.22.53.5-1.7-1.8-1.9-1.51.6-1.8-1.8-0.0-1.81.11.2
Run reversals in cocaine runway, males1.82.04.1-1.7-1.7-2.0-1.31.2-1.8-1.80.1-0.31.21.2
Latency to leave start box in cocaine runway0.71.02.50.30.3-0.10.7-0.6-0.9-1.01.5-1.21.41.6
Latency to leave start box in cocaine runway, F1.41.74.20.40.3-0.20.8-0.8-1.3-1.42.0-1.51.82.1
Latency to leave start box in cocaine runway, M0.20.10.40.10.20.3-0.10.10.40.5-0.40.6-0.5-0.5
Std. dev. time between licks in bursts0.71.32.7-0.9-1.0-1.3-0.50.5-1.5-1.50.7-1.11.21.6
Total sessions with >9 infusions0.40.52.00.61.0-0.21.3-1.40.00.10.80.10.30.2
Short access day 1 total inactive lever presses0.20.40.9-0.7-0.6-0.5-0.80.60.00.1-1.00.5-0.5-0.6
Short access day 10 total inactive lever presses0.21.33.1-0.4-0.40.2-0.90.61.01.1-1.71.4-1.6-1.6
Short access day 1 total infusions0.30.51.90.61.0-0.21.3-1.40.10.10.80.10.30.1
Short access day 10 total infusions0.10.10.50.40.50.00.7-0.60.30.30.2-0.1-0.2-0.1
Short access total infusions0.60.82.60.91.20.11.6-1.60.20.21.0-0.50.40.2
Short access day 1 locomotion0.20.31.1-0.8-0.5-1.1-0.40.3-0.2-0.1-0.70.3-0.4-0.2
Short access day 10 total locomotion0.52.04.6-1.7-1.3-1.4-1.92.00.10.2-2.10.9-1.3-1.2
Short access total locomotion0.20.30.8-0.7-0.4-0.9-0.50.5-0.00.0-0.80.5-0.5-0.4
One hour access (0.3 mA shock)0.20.20.40.30.30.40.6-0.30.50.6-0.20.1-0.4-0.6
Compulsive drug intake0.00.00.1-0.1-0.0-0.2-0.10.0-0.3-0.30.20.00.40.2
One hour access (shock baseline)0.00.10.2-0.2-0.2-0.30.00.20.10.2-0.4-0.3-0.3-0.3
Social response proportion0.70.81.4-1.0-0.9-1.0-1.11.2-1.0-1.1-0.1-1.00.60.7
Social responses6.07.913.0-3.6-3.4-3.5-3.43.5-3.1-3.1-0.9-1.51.41.5
Social time0.71.12.21.31.31.51.0-0.91.31.30.10.6-0.7-0.7
Soleus weight3.811.120.74.64.54.44.4-4.33.13.02.11.0-0.7-0.7
Bone: stiffness2.13.98.52.62.71.72.9-2.90.90.82.3-1.00.70.8
Tibialis anterior weight0.82.95.52.32.22.32.1-2.11.61.51.10.7-0.4-0.3
Time to tail flick, vehicle, before self-admin0.91.22.1-1.1-1.2-1.5-0.90.8-1.4-1.40.40.51.20.9
Time to tail flick, vehicle, after self-admin0.51.02.5-0.6-0.70.1-1.31.30.70.7-1.60.8-1.3-1.2
Time to tail flick, test, before self-admin1.21.42.3-0.8-1.0-1.3-0.40.3-1.5-1.50.8-1.51.31.4
Time to tail flick, test, after self-admin0.10.20.40.00.1-0.30.3-0.2-0.4-0.50.6-0.20.60.6
Delta time to tail flick, vehicle, before/after SA1.71.83.71.11.01.90.3-0.21.91.9-1.00.6-1.7-1.6
Delta time to tail flick, test, before/after SA0.81.02.90.10.20.7-0.30.41.01.0-1.11.7-1.2-1.3
Tibia length0.61.63.7-1.7-1.8-1.1-1.91.8-0.7-0.7-1.30.0-0.2-0.2
Ambulatory time before self-admin0.10.30.6-0.8-0.6-0.6-0.60.7-0.5-0.5-0.40.20.1-0.1
Ambulatory time after self-admin0.00.00.00.00.20.10.10.1-0.0-0.10.10.20.10.1
Bone: tissue strength3.13.37.12.42.61.82.7-2.71.11.11.8-0.30.30.3
Total heroin consumption1.51.72.9-1.7-1.7-1.6-1.51.6-1.5-1.5-0.3-0.60.80.7
Bone: trabecular number0.91.73.0-0.7-0.7-1.3-0.30.3-1.7-1.71.1-1.61.71.7
Bone: trabecular spacing2.13.06.30.40.31.2-0.30.32.12.1-2.12.4-2.5-2.5
Bone: trabecular thickness4.05.611.90.20.3-1.01.2-1.3-2.4-2.53.3-3.53.43.4
Bone: trabecular tissue density2.84.88.02.82.82.82.6-2.52.52.40.61.2-1.2-1.2
Water consumed over 24 hours0.40.71.60.91.00.61.0-1.2-0.1-0.11.3-0.80.80.7
Number of responses in last shaping day1.11.42.8-1.7-1.4-1.7-1.51.5-0.6-0.4-1.40.6-0.5-0.4