Hub : Genes

LOC120093526

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability LOC120093526 0.03 0.03 1.6e-03 0.01 0.01 0.01 0.01 1.9e-02 1.1e-02 3.8e-02 2.1e-02
2 NAcc gene expression LOC120093526 0.03 0.03 8.9e-04 0.02 0.02 0.02 0.02 1.1e-03 1.2e-03 6.5e-04 2.6e-04
3 Adipose isoform ratio XR_010053543.1 0.04 0.03 8.2e-05 0.03 0.03 0.03 0.03 1.4e-04 4.7e-04 8.2e-04 4.6e-04
4 Brain gene expression LOC120093526 0.06 0.04 1.6e-05 0.03 0.04 0.04 0.04 6.7e-04 1.3e-04 2.0e-04 1.0e-04
5 Adipose isoform ratio XR_010053542.1 0.05 0.03 1.6e-04 0.03 0.03 0.02 0.03 2.6e-04 4.2e-04 8.8e-04 6.5e-04
6 PL alternative TSS XR_010053543.1 0.02 0.02 5.3e-03 0.01 0.01 0.01 0.01 5.8e-02 8.3e-03 1.5e-02 2.3e-02
7 Adipose gene expression LOC120093526 0.03 0.02 3.7e-03 0.01 0.02 0.02 0.02 4.5e-02 2.6e-03 4.3e-03 6.1e-03
8 PL gene expression LOC120093526 0.04 0.03 4.7e-03 -0 0.01 0.01 0.01 5.1e-01 1.0e-02 1.7e-02 5.0e-02
9 PL isoform ratio XR_010053542.1 0.04 0.04 7.9e-03 0.02 0.02 0.01 0.01 3.5e-03 4.5e-03 7.4e-03 1.9e-02
10 Adipose isoform ratio XR_010053544.1 0.05 0.04 1.4e-04 0.04 0.03 0.03 0.03 4.8e-05 3.9e-04 5.8e-04 4.8e-04
11 Eye alternative TSS XR_005486764.2 0.46 0.22 7.6e-03 0.1 0.09 0.1 0.08 1.2e-02 2.0e-02 1.5e-02 2.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.72.96.40.20.20.80.91.0-1.7-1.82.42.5-2.5-2.4
Area under the delay curve0.00.00.20.20.1-0.40.20.10.0-0.00.20.0-0.2-0.3
BMI with tail5.017.132.05.75.5-5.45.35.34.03.92.4-1.11.11.1
BMI without tail1.34.17.52.72.7-2.72.52.62.12.01.0-0.70.70.7
Body weight0.93.88.22.42.4-2.91.92.02.22.20.4-1.11.11.1
Weight adjusted by age0.00.10.2-0.2-0.2-0.0-0.4-0.40.10.1-0.40.10.30.2
Bone surface3.76.713.9-0.4-0.31.90.80.9-3.0-3.13.23.6-3.7-3.6
Bone volume3.76.614.1-0.1-0.01.61.11.2-2.8-2.93.43.6-3.7-3.6
Breakpoint value in progressive ratio session0.60.71.4-1.2-1.01.0-1.0-1.1-0.7-0.6-0.7-0.6-0.10.2
Number of licking bursts1.72.85.32.01.8-2.31.51.62.12.1-0.0-1.01.41.2
Context. condit. distance diff. score0.20.20.40.60.5-0.60.50.60.50.50.2-0.00.20.2
Locomotion velocity, session 10.91.02.40.30.30.00.60.5-0.9-0.91.51.6-1.4-1.4
Locomotion distance, session 11.31.73.5-0.4-0.41.00.10.1-1.6-1.61.41.9-1.8-1.8
Locomotion velocity, session 22.52.95.1-1.2-1.31.8-0.7-0.6-2.3-2.31.22.1-2.1-2.1
Locomotion distance, session 23.04.27.2-2.0-2.02.2-1.5-1.5-2.7-2.70.72.2-2.1-2.1
Locomotion velocity, session 32.83.26.2-2.5-2.42.1-2.4-2.5-1.6-1.5-1.30.4-0.2-0.2
Locomotion distance, session 30.10.10.2-0.3-0.20.0-0.4-0.40.00.0-0.40.00.20.2
Stereotopy head waving bouts, day 33.74.47.7-2.8-2.72.8-2.4-2.5-2.3-2.2-0.70.9-1.0-1.0
Stereotopy head waving duration, day 32.63.16.6-2.3-2.32.6-1.9-1.9-1.9-1.8-0.60.7-0.8-0.8
Locomotion velocity, session 70.20.20.6-0.2-0.30.4-0.1-0.0-0.6-0.60.40.8-0.6-0.6
Locomotion distance, session 70.30.40.90.30.2-0.60.00.10.90.9-0.7-0.70.90.9
Stereotopy head waving bouts, day 71.31.42.6-1.0-0.91.2-0.6-0.7-1.6-1.60.71.3-1.4-1.4
Stereotopy head waving duration, day 71.41.73.1-0.9-0.81.2-0.4-0.6-1.7-1.81.01.5-1.7-1.7
Locomotion velocity, session 82.22.74.5-1.2-1.31.5-0.8-0.8-2.1-2.11.12.1-2.0-2.0
Locomotion distance, session 80.40.50.9-0.7-0.90.7-0.6-0.6-0.9-0.90.20.9-0.7-0.7
Degree of sensitization distance0.40.40.80.90.8-0.70.80.90.50.50.5-0.10.00.0
Degree of sensitization stereotypy0.40.41.00.30.3-0.00.50.4-0.5-0.61.00.8-1.0-1.0
Conditioned locomotion1.51.83.21.01.1-1.50.50.41.81.8-0.9-1.51.71.5
Cocaine response after cond. corrected2.02.44.31.61.5-1.91.31.12.12.1-0.4-1.21.71.4
Cocaine response after cond. not corrected2.42.84.91.71.6-2.01.31.12.22.2-0.6-1.41.81.7
Cocaine response before conditioning0.30.40.7-0.8-0.50.9-0.7-0.7-0.8-0.7-0.1-0.0-0.6-0.2
Saline control response0.60.81.60.91.0-1.30.50.51.11.1-0.3-1.10.90.9
Bone: connectivity density1.01.63.90.10.10.70.60.6-1.3-1.31.72.0-1.8-1.7
Bone: cortical apparent density0.70.92.21.31.2-0.91.41.50.80.70.8-0.10.00.0
Bone: cortical area1.31.94.81.01.1-0.11.61.7-0.7-0.72.21.6-1.6-1.6
Bone: cortical porosity0.30.30.90.00.00.30.30.4-0.5-0.50.70.9-0.8-0.7
Bone: cortical porosity0.70.81.70.30.30.30.70.9-0.7-0.71.31.3-1.2-1.1
Bone: cortical thickness1.11.84.51.61.7-0.81.92.10.20.11.90.8-0.9-0.9
Bone: cortical thickness0.60.71.21.01.0-1.00.70.81.11.1-0.1-0.80.70.7
Bone: cortical tissue density0.50.61.51.11.0-0.71.21.20.60.60.7-0.10.0-0.0
Condit. Reinf. active minus inactive responses1.31.53.0-1.6-1.71.6-1.5-1.4-1.2-1.2-0.50.8-0.4-0.4
Condit. Reinf. active-inactive response ratio0.20.30.5-0.6-0.60.5-0.6-0.60.00.1-0.7-0.30.50.5
Condit. Reinf. active responses2.42.94.8-2.0-2.12.2-1.7-1.5-2.1-2.0-0.01.6-1.3-1.3
Condit. Reinf. inactive responses1.82.23.7-1.4-1.41.6-1.1-1.0-1.9-1.90.61.7-1.6-1.6
Incentive salience index mean1.31.62.5-1.3-1.51.5-1.1-0.9-1.6-1.60.31.5-1.1-1.1
Condit. Reinf. lever presses1.41.94.8-0.5-0.80.8-0.1-0.2-1.7-1.81.42.2-1.9-1.9
Condit. Reinf. active minus inactive responses1.62.04.0-1.9-1.71.5-2.0-2.0-0.4-0.4-1.9-0.80.80.8
Condit. Reinf. active-inactive response ratio1.51.74.3-0.9-0.80.3-1.3-1.40.70.8-2.1-1.51.61.7
Condit. Reinf. active responses1.01.42.9-1.7-1.51.6-1.6-1.6-1.0-0.9-1.00.1-0.0-0.0
Condit. Reinf. inactive responses0.40.61.0-0.7-0.61.0-0.5-0.4-1.0-1.00.30.8-0.8-0.8
Condit. Reinf. lever presses1.62.24.4-2.0-1.91.7-2.1-2.1-0.8-0.7-1.6-1.00.50.4
Condit. Reinf. lever reinforcers received0.81.12.2-1.5-1.31.3-1.5-1.5-0.6-0.5-1.2-0.30.30.3
Conditioned reinforcement - actives0.10.10.4-0.10.10.50.50.3-0.00.00.00.60.10.0
Conditioned reinforcement - inactives0.30.50.90.50.7-0.30.60.70.91.0-0.4-0.40.80.9
Conditioned locomotion1.62.16.5-1.8-1.62.6-1.0-1.1-1.7-1.6-0.21.1-0.8-0.9
Patch foraging indifference point 0 sec2.03.78.22.62.7-2.12.92.91.21.21.90.2-0.3-0.2
Patch foraging indifference point AUC0.40.61.5-1.0-1.20.8-1.2-1.2-0.5-0.4-0.80.00.20.0
Delay disc. indifference point, 0s delay1.92.14.91.41.0-0.91.71.7-0.4-0.52.21.8-1.5-1.7
Delay disc. indifference point, 16s delay0.10.10.2-0.4-0.30.3-0.4-0.4-0.4-0.40.0-0.0-0.3-0.5
Delay disc. indifference point, 2s delay0.40.41.10.60.2-0.60.70.7-0.2-0.31.00.2-0.8-0.9
Delay disc. indifference point, 24s delay0.20.20.70.60.5-0.80.50.40.40.30.3-0.10.0-0.1
Delay disc. indifference point, 4s delay0.70.71.4-0.5-0.60.7-0.2-0.2-1.1-1.10.71.0-1.1-1.2
Delay disc. indifference point, 8s delay0.30.30.70.40.3-0.80.10.10.80.8-0.5-0.40.80.7
Indifference point function ln k0.10.10.30.30.5-0.10.40.50.30.30.1-0.30.10.2
Indifference point function log k0.10.10.30.30.5-0.10.40.50.30.30.1-0.30.10.2
Patch foraging total patch changes 0 sec1.83.37.42.42.5-1.92.72.71.21.11.70.1-0.3-0.1
Patch foraging total patch changes 12 sec1.31.73.11.61.6-1.81.41.41.51.50.3-0.70.80.6
Patch foraging total patch changes 18 sec0.00.00.10.20.1-0.30.20.2-0.0-0.10.30.1-0.3-0.2
Patch foraging total patch changes 24 sec0.30.40.90.80.8-0.71.00.90.10.10.9-0.1-0.5-0.4
Patch foraging total patch changes 6 sec1.11.73.71.81.9-1.31.81.90.80.81.20.4-0.1-0.2
Patch foraging time to switch 0 sec0.30.61.30.70.7-0.30.90.8-0.2-0.31.11.1-0.8-0.9
Patch foraging water rate 0 sec0.51.11.80.80.8-1.20.50.61.31.4-0.6-1.31.21.3
Patch foraging water rate 12 sec0.71.42.31.01.1-1.20.80.81.51.5-0.5-1.51.21.5
Patch foraging water rate 18 sec2.03.18.40.00.0-1.0-0.7-0.61.81.9-2.2-2.92.32.6
Patch foraging water rate 24 sec3.75.29.11.41.4-2.40.50.62.93.0-1.8-3.02.83.0
Patch foraging water rate 6 sec1.11.63.9-0.8-0.60.2-1.1-1.00.80.8-1.9-2.01.51.9
Seeking ratio, delayed vs. immediate footshock1.01.33.1-1.4-1.21.8-0.8-0.8-1.5-1.50.1-0.2-1.0-0.9
Distance traveled before self-admin0.81.02.0-1.4-1.31.2-1.3-1.3-1.0-1.0-0.6-0.0-0.4-0.2
Distance traveled after self-admin0.00.00.1-0.00.1-0.1-0.1-0.30.0-0.0-0.1-0.20.0-0.0
Extensor digitorum longus weight3.614.225.34.84.7-5.04.14.24.34.20.9-2.12.22.1
Bone: elastic displacement0.00.00.00.00.10.00.10.1-0.1-0.10.20.0-0.1-0.2
Bone: elastic work0.60.81.71.11.1-0.71.21.30.10.11.30.4-0.6-0.7
Bone: endosteal estimation0.40.92.01.01.0-0.41.41.4-0.0-0.01.30.8-0.8-0.8
Bone: endosteal perimeter0.61.32.3-0.8-0.81.3-0.3-0.2-1.5-1.50.81.4-1.4-1.4
Epididymis fat weight0.20.82.0-0.4-0.5-0.2-0.7-0.60.70.8-1.4-1.31.21.3
Delta time in closed arm before/after self-admin3.43.27.81.11.2-1.50.60.72.22.3-1.4-2.82.22.2
Delta time in open arm before/after self-admin0.60.61.61.01.1-1.30.80.70.70.70.40.10.20.2
Diff in mean of infusions in LGA sessions1.11.32.8-1.7-1.51.5-1.4-1.6-0.9-0.9-1.00.1-0.0-0.0
Delay discount exponential model param0.00.00.1-0.10.10.30.00.00.00.1-0.10.00.20.3
Extinction: sum of active levers before priming1.11.22.5-1.4-1.40.9-1.4-1.5-0.2-0.1-1.6-0.70.80.8
Active lever presses in extinction session 60.20.20.6-0.4-0.60.5-0.3-0.3-0.6-0.60.10.8-0.5-0.4
Bone: final force2.23.57.02.22.3-1.22.62.60.10.02.61.5-1.4-1.4
Bone: final moment2.13.47.02.12.3-1.22.62.60.10.02.61.4-1.4-1.4
Food consumed during 24 hour testing period0.20.30.50.70.7-0.70.60.70.40.40.4-0.20.1-0.1
Glucose0.91.42.81.61.5-1.71.41.41.21.10.6-0.30.40.4
Heart weight0.30.41.1-0.7-0.70.4-0.8-0.80.20.2-1.0-0.70.70.6
Delay discount hyperbolic model param0.10.10.3-0.4-0.20.5-0.4-0.40.00.1-0.5-0.10.40.5
Intermittent access intake day 1-15 change0.30.71.4-0.9-0.70.7-0.9-1.00.10.1-1.2-1.10.70.9
Intermittent access intake escalation0.30.71.4-0.8-0.60.6-0.9-0.90.10.2-1.2-1.10.70.9
Intermittent access intake escalation 20.60.71.5-1.0-1.00.8-1.1-1.2-0.3-0.2-0.9-0.80.30.5
Intermitt. access day 1 inactive lever presses0.41.43.7-0.7-0.80.0-1.3-1.10.80.9-1.9-1.11.51.5
Intermitt. access day 15 inactive lever presses0.30.71.6-1.1-1.30.6-1.2-1.1-0.4-0.3-1.00.10.20.5
Intermitt. access escalation Index0.30.41.00.20.20.20.40.4-0.6-0.61.00.7-0.9-0.9
Intermittent access day 1 total infusions0.10.20.40.40.3-0.20.70.40.50.5-0.0-0.00.40.2
Intermittent access day 15 total infusions0.00.00.2-0.1-0.10.50.40.2-0.1-0.00.0-0.0-0.00.1
Intermittent access terminal intake (last 3 days)0.20.20.6-0.3-0.20.80.40.2-0.6-0.60.50.6-0.6-0.4
Intermittent access total infusions0.10.10.60.20.30.20.80.60.00.00.40.5-0.1-0.1
Intermittent access day 1 locomotion0.30.31.00.20.3-0.30.1-0.10.80.8-0.7-0.41.00.7
Intermittent access day 15 total locomotion0.20.30.7-0.6-0.40.7-0.3-0.50.10.2-0.8-0.40.50.7
Intermittent access total locomotion0.10.10.3-0.4-0.30.5-0.1-0.30.00.1-0.5-0.20.40.4
Intermittent access standard deviation0.40.92.7-1.1-0.91.6-0.8-0.8-1.1-1.0-0.00.8-0.6-0.5
Left kidney weight0.00.10.20.10.0-0.4-0.2-0.30.40.4-0.4-0.40.50.4
Right kidney weight0.10.51.3-0.8-0.80.3-1.1-1.10.00.1-1.1-0.60.70.3
Cocaine induced anxiety1.42.03.8-1.4-1.51.7-0.9-0.9-2.0-2.00.60.7-1.6-1.5
Post-drug Anxiety1.92.14.6-0.9-1.01.5-0.2-0.2-2.1-2.11.40.4-2.2-1.8
Baseline Anxiety0.00.00.20.10.1-0.10.20.20.00.00.2-0.4-0.10.0
Tail length2.08.016.9-3.9-3.73.4-4.1-3.9-2.2-2.1-2.40.00.0-0.1
Length with tail0.93.89.1-2.7-2.41.9-3.0-2.8-1.0-0.9-2.2-0.60.60.6
Length without tail0.20.81.40.91.0-1.20.60.61.11.1-0.2-0.80.80.7
Times rat made contact with spout1.01.12.31.21.2-1.50.80.91.41.4-0.2-0.50.91.0
Lifetime Intake0.50.62.20.80.9-0.11.51.30.20.20.80.5-0.3-0.1
Liver weight, left0.30.40.90.90.8-1.00.70.80.70.70.2-0.30.40.3
Liver weight, right0.20.30.7-0.4-0.4-0.2-0.8-0.70.20.2-0.8-0.60.60.5
Locomotor activity2.33.65.6-2.3-2.22.4-2.0-2.0-2.3-2.2-0.21.1-1.4-1.3
Locomotor testing distance1.01.83.3-1.6-1.51.8-1.3-1.3-1.7-1.7-0.00.7-1.1-1.1
Locomotor testing rearing0.10.10.2-0.10.1-0.2-0.3-0.30.30.3-0.5-0.50.40.4
Locomotion in novel chamber0.00.00.10.20.30.00.30.20.10.10.2-0.2-0.0-0.0
Locomotion in novel chamber post-restriction2.33.77.2-2.6-2.72.3-2.7-2.6-1.7-1.7-1.2-0.6-0.4-0.4
Fecal boli incidents, locomotor time 10.81.12.01.01.1-1.40.60.51.31.3-0.4-1.21.01.0
Change in fecal boli incidents, locomotor task1.41.42.3-0.7-0.81.2-0.4-0.3-1.5-1.50.91.5-1.5-1.5
Time >=10cm from walls, locomotor time 10.91.02.20.70.8-0.21.11.0-0.5-0.51.51.5-1.2-1.2
Bouts of movement, locomotor time 10.40.50.9-1.0-0.90.8-0.9-0.9-0.4-0.4-0.70.30.20.2
Total resting periods, locomotor time 10.80.91.9-1.4-1.31.2-1.3-1.3-0.8-0.8-0.80.3-0.0-0.0
Rest time, locomotor task time 10.50.60.9-0.8-0.80.9-0.7-0.7-1.0-1.00.10.7-0.7-0.7
Distance moved, locomotor task time 10.81.22.80.90.9-0.31.41.3-0.4-0.41.71.4-1.2-1.2
Vertical activity count, locomotor time 10.40.91.91.21.2-1.01.41.30.90.90.5-0.10.30.3
Time >=10cm from walls, locomotor time 20.71.01.41.11.1-1.21.01.01.21.2-0.0-1.00.80.8
Bouts of movement, locomotor time 20.50.93.3-0.4-0.30.8-0.2-0.1-1.1-1.10.71.8-1.1-1.1
Total resting periods, locomotor time 20.61.14.2-0.4-0.20.9-0.20.0-1.2-1.20.92.0-1.3-1.3
Rest time, locomotor task time 20.40.51.0-0.2-0.20.5-0.0-0.0-0.9-0.90.71.0-1.0-1.0
Distance moved, locomotor task time 20.30.30.70.10.2-0.3-0.0-0.10.70.7-0.7-0.50.90.9
Vertical activity count, locomotor time 21.21.63.01.21.1-1.60.80.81.71.7-0.6-1.11.41.4
Light reinforcement 11.74.27.9-2.8-2.52.8-2.3-2.2-2.3-2.3-0.70.9-1.2-0.7
Light reinforcement 20.60.91.8-1.3-1.11.3-1.2-1.0-1.0-1.0-0.40.4-0.5-0.2
Bone: marrow area0.40.81.80.90.9-0.41.31.3-0.0-0.11.30.7-0.7-0.7
Bone: maximum diameter1.01.93.3-0.9-0.81.6-0.3-0.1-1.8-1.81.11.6-1.7-1.7
Bone: maximum force1.93.37.12.22.4-1.42.62.70.40.32.41.1-1.1-1.2
Bone: maximum moment1.93.37.12.32.4-1.42.62.70.40.32.41.1-1.1-1.2
Mean time between licks in bursts0.30.71.5-1.1-1.21.2-1.0-1.0-0.5-0.5-0.8-0.30.3-0.1
Mean num. licks in bursts0.30.50.9-0.9-0.70.9-0.7-0.8-0.8-0.8-0.10.5-0.6-0.3
Cd content in liver0.20.20.7-0.6-0.90.8-0.3-0.3-0.5-0.5-0.10.1-0.1-0.2
Co content in liver1.71.94.0-1.9-2.01.5-2.0-2.0-0.8-0.7-1.5-0.40.40.4
Cu content in liver0.81.02.30.50.50.30.91.1-0.7-0.71.51.4-1.3-1.2
Fe content in liver0.20.20.40.50.5-0.40.40.40.60.6-0.1-0.10.50.5
K content in liver1.00.91.6-0.9-0.81.3-0.6-0.6-1.3-1.30.41.0-1.0-1.0
Mg content in liver1.01.01.5-1.2-1.21.2-1.1-1.0-1.2-1.2-0.00.8-0.8-0.8
Mn content in liver3.74.17.5-1.3-1.22.0-0.5-0.6-2.6-2.61.62.7-2.6-2.5
Na content in liver0.30.40.90.30.4-0.10.50.4-0.4-0.50.90.9-0.9-0.7
Rb content in liver0.81.02.30.40.30.30.60.9-0.8-0.81.51.2-1.4-1.5
Se content in liver0.00.00.1-0.1-0.10.1-0.0-0.1-0.1-0.1-0.00.40.0-0.0
Sr content in liver0.30.30.6-0.4-0.40.5-0.4-0.40.20.3-0.8-0.70.70.7
Zn content in liver2.73.06.4-1.9-1.81.1-2.5-2.20.10.2-2.5-1.41.61.6
Bone: minimum diameter0.50.92.20.50.40.31.01.1-0.7-0.71.51.2-1.2-1.2
Time in familiar zone, hab. session 12.92.86.1-2.3-2.21.7-2.4-2.5-1.1-1.0-1.7-0.30.30.3
Time in novel zone, hab. session 12.52.55.31.91.8-1.12.32.30.30.22.21.2-1.1-1.1
Total zone transitions, hab. session 11.11.63.0-0.7-0.81.1-0.3-0.3-1.6-1.61.11.7-1.7-1.7
Total locomotion distance, hab. session 13.14.47.5-1.5-1.62.2-0.9-0.9-2.7-2.71.42.7-2.5-2.5
Locomotion velocity, hab. session 12.53.66.1-1.6-1.72.2-1.1-1.1-2.5-2.50.92.2-2.1-2.1
Time in familiar zone, hab. session 23.23.37.1-2.4-2.41.8-2.7-2.6-0.8-0.7-2.2-0.90.80.8
Time in novel zone, hab. session 23.63.77.92.52.4-1.82.82.80.60.52.41.1-1.0-1.0
Total zone transitions, hab. session 21.72.14.90.80.8-0.21.31.3-1.0-1.12.22.1-1.9-1.9
Total locomotion distance, hab. session 20.91.22.6-0.6-0.60.8-0.3-0.3-1.4-1.40.91.6-1.4-1.4
Locomotion velocity, hab. session 21.31.83.9-0.7-0.70.9-0.3-0.3-1.7-1.71.22.0-1.8-1.8
Novel to familiar place preference ratio2.22.45.11.81.8-1.22.12.10.1-0.02.31.2-1.3-1.3
Novelty place preference1.61.83.91.41.4-0.81.71.8-0.1-0.22.01.2-1.3-1.3
Time in novel zone, NPP test1.92.04.11.71.6-1.02.02.00.10.02.01.1-1.2-1.2
Total zone transitions, NPP test0.50.81.80.70.7-0.60.90.9-0.3-0.41.31.2-1.0-1.0
Total locomotion distance, NPP test0.70.92.50.20.10.10.50.5-0.9-1.01.31.6-1.4-1.4
Locomotion velocity, NPP test0.60.92.4-0.1-0.20.40.10.1-1.1-1.11.11.5-1.3-1.3
Intraocular pressure1.01.43.4-0.5-0.6-0.5-1.0-1.10.90.9-1.7-1.81.41.6
Delta distance traveled before/after self-admin0.40.50.90.90.9-0.90.70.60.80.80.2-0.40.40.2
Delta ambulatory time before/after self-admin0.30.40.90.90.9-0.70.90.80.40.30.70.2-0.1-0.4
Parametrial fat weight0.30.61.41.01.1-0.71.21.10.40.40.90.3-0.2-0.3
Pavlov. Cond. lever latency1.01.22.70.20.5-0.5-0.2-0.21.31.3-1.3-1.71.61.6
Pavlov. Cond. magazine entry latency0.91.22.9-1.5-1.71.2-1.4-1.3-1.0-0.9-0.70.4-0.2-0.2
Pavlov. Cond. change in total contacts0.10.10.40.40.1-0.40.40.60.10.10.40.3-0.2-0.2
Pavlov. Cond. index score0.60.71.2-0.7-1.00.7-0.5-0.5-1.1-1.10.41.0-0.9-0.9
Pavlov. Cond. latency score0.91.12.0-0.8-1.10.9-0.4-0.4-1.4-1.40.71.4-1.3-1.3
Pavlov. Cond. lever contacts0.81.02.50.0-0.30.20.40.4-1.0-1.11.31.6-1.4-1.4
Pavlov. Cond. magazine entry number0.40.51.40.91.2-0.61.00.90.50.50.6-0.10.0-0.0
Pavlov. Cond. intertrial magazine entries0.40.51.1-0.2-0.1-0.1-0.5-0.40.60.7-1.1-1.11.01.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.2-0.8-1.10.8-0.6-0.6-1.1-1.10.21.0-0.8-0.8
Pavlov. Cond. response bias0.30.41.2-0.8-1.10.5-0.8-0.8-0.6-0.6-0.40.3-0.2-0.2
Pavlov. Cond. lever latency1.01.32.51.61.5-1.31.61.51.01.00.80.50.20.3
Pavlov. Cond. magazine entry latency1.51.83.3-1.8-1.81.6-1.8-1.6-1.3-1.3-0.70.2-0.4-0.4
Pavlov. Cond. change in total contacts0.40.61.3-1.1-1.01.0-1.1-1.1-0.5-0.5-0.8-0.40.10.1
Pavlov. Cond. index score1.21.63.1-1.8-1.71.6-1.7-1.6-1.1-1.0-1.0-0.4-0.1-0.1
Pavlov. Cond. latency score1.31.83.4-1.8-1.81.6-1.8-1.7-1.3-1.3-0.8-0.1-0.4-0.4
Pavlov. Cond. lever contacts0.91.32.7-1.5-1.51.2-1.6-1.5-0.8-0.8-1.0-0.80.10.0
Pavlov. Cond. magazine entry number1.51.93.51.91.8-1.81.81.61.41.40.7-0.10.50.5
Pavlov. Cond. intertrial magazine entries0.81.21.91.21.4-1.41.01.01.31.3-0.0-0.90.80.9
Pavlov. Cond. lever-magazine prob. diff.1.41.83.5-1.9-1.81.8-1.8-1.6-1.3-1.2-0.8-0.2-0.3-0.3
Pavlov. Cond. response bias1.52.04.1-1.9-1.91.6-2.0-1.9-0.9-0.9-1.3-0.90.20.1
Time in closed arm before self-admin0.40.51.40.30.30.20.40.5-0.7-0.71.20.8-1.1-1.1
Time in closed arm after self-admin0.50.52.30.60.8-0.30.60.80.60.60.2-1.50.30.4
Time in open arm before self-admin0.00.00.3-0.1-0.10.30.10.00.00.1-0.10.50.10.1
Time in open arm after self-admin1.21.32.81.41.5-1.71.21.01.31.30.20.40.70.7
Bone: periosteal estimation1.12.35.51.21.2-0.21.92.0-0.6-0.72.31.6-1.7-1.7
Bone: periosteal perimeter0.91.53.0-0.1-0.10.80.50.7-1.4-1.41.61.7-1.7-1.7
Bone: post-yield work0.30.40.90.90.9-0.70.90.90.50.40.5-0.1-0.0-0.1
Progressive ratio test 1 active lever presses0.30.30.80.70.6-0.40.90.80.60.60.10.00.40.3
Progressive ratio test 1 breakpoint0.30.30.80.70.6-0.50.90.80.60.70.10.00.40.3
Progressive ratio test 1 inactive lever presses0.10.20.7-0.6-0.60.8-0.2-0.2-0.4-0.3-0.20.2-0.0-0.0
Progressive ratio test 2 active lever presses0.10.10.4-0.3-0.30.50.2-0.0-0.2-0.2-0.10.6-0.10.0
Progressive ratio test 2 breakpoint0.10.10.5-0.4-0.40.60.1-0.2-0.3-0.3-0.10.7-0.1-0.0
Progressive ratio test 2 inactive lever presses0.20.41.00.20.30.31.00.7-0.3-0.30.71.0-0.6-0.4
Incentive Sensitization - Responses0.20.30.5-0.7-0.70.5-0.5-0.7-0.4-0.3-0.50.50.00.1
Incentive Sensitization - Breakpoint0.30.40.7-0.8-0.80.7-0.6-0.8-0.6-0.6-0.40.7-0.2-0.1
Sum of active levers in priming session hrs 5-60.10.10.5-0.4-0.40.2-0.3-0.4-0.1-0.1-0.4-0.70.10.2
Progressive ratio0.71.12.11.31.4-1.21.11.01.31.30.10.20.80.8
Food seeking constrained by brief footshock1.11.43.3-1.5-1.71.0-1.8-1.8-0.8-0.8-1.0-0.1-0.00.1
Seeking ratio, punishment vs. effort1.52.14.4-1.9-2.11.5-2.0-2.0-1.3-1.3-0.9-0.7-0.4-0.4
Retroperitoneal fat weight1.77.212.03.23.3-3.52.62.53.33.30.1-2.02.02.1
Reaction time number correct0.81.52.71.21.1-1.60.70.61.61.6-0.5-1.31.31.3
Reaction time mean minus median0.51.22.3-1.4-1.51.4-1.4-1.4-1.1-1.1-0.4-0.1-0.4-0.5
Reaction time mean minus median AUC1.02.54.4-1.4-1.61.8-1.0-1.1-2.1-2.10.81.3-1.7-1.8
Reaction time num false alarms0.50.61.51.01.2-1.20.80.90.90.90.20.00.40.4
Reaction time num false alarms AUC0.50.81.71.01.2-1.30.70.81.11.1-0.0-0.40.70.7
Reaction time trials correct on left0.81.52.71.21.1-1.60.70.61.61.6-0.5-1.31.31.3
Reaction time trials on left0.71.42.51.11.1-1.60.70.61.61.5-0.4-1.21.21.2
Reaction time mean1.01.72.8-1.3-1.61.6-0.9-1.0-1.7-1.70.40.7-1.2-1.4
Reaction time mean AUC0.61.01.9-0.8-1.11.2-0.4-0.6-1.4-1.40.60.6-1.1-1.3
Median of all reaction times0.81.22.1-0.9-1.31.3-0.5-0.7-1.4-1.40.60.8-1.2-1.3
Reaction time omissions0.20.41.0-0.0-0.10.50.30.2-0.7-0.70.80.3-0.8-1.0
Reaction time false alarm rate0.10.20.40.50.6-0.40.40.60.10.10.50.4-0.2-0.2
Reaction time premature initiation rate1.01.33.4-1.4-1.20.8-1.6-1.8-0.1-0.0-1.7-0.70.91.0
Reaction time premature initiations0.91.64.0-0.7-0.6-0.1-1.2-1.50.80.9-2.0-1.51.61.7
Std. dev. reaction times0.61.01.7-1.0-1.31.3-0.8-0.9-1.3-1.30.20.6-0.9-1.0
Reaction time trials completed0.71.42.51.11.1-1.60.70.61.61.5-0.4-1.21.21.2
Reaction time trials AUC1.01.83.21.21.2-1.80.80.61.81.8-0.6-1.41.41.5
Run reversals in cocaine runway, females2.52.53.5-1.7-1.81.9-1.5-1.6-1.8-1.8-0.01.8-1.1-1.2
Run reversals in cocaine runway, males2.02.04.1-1.7-1.72.0-1.3-1.2-1.8-1.80.10.3-1.2-1.2
Latency to leave start box in cocaine runway0.91.02.50.30.30.10.70.6-0.9-1.01.51.2-1.4-1.6
Latency to leave start box in cocaine runway, F1.51.74.20.40.30.20.80.8-1.3-1.42.01.5-1.8-2.1
Latency to leave start box in cocaine runway, M0.20.10.40.10.2-0.3-0.1-0.10.40.5-0.4-0.60.50.5
Std. dev. time between licks in bursts1.01.32.7-0.9-1.01.3-0.5-0.5-1.5-1.50.71.1-1.2-1.6
Total sessions with >9 infusions0.40.52.00.61.00.21.31.40.00.10.8-0.1-0.3-0.2
Short access day 1 total inactive lever presses0.30.40.9-0.7-0.60.5-0.8-0.60.00.1-1.0-0.50.50.6
Short access day 10 total inactive lever presses0.51.33.1-0.4-0.4-0.2-0.9-0.61.01.1-1.7-1.41.61.6
Short access day 1 total infusions0.40.51.90.61.00.21.31.40.10.10.8-0.1-0.3-0.1
Short access day 10 total infusions0.10.10.50.40.5-0.00.70.60.30.30.20.10.20.1
Short access total infusions0.60.82.60.91.2-0.11.61.60.20.21.00.5-0.4-0.2
Short access day 1 locomotion0.20.31.1-0.8-0.51.1-0.4-0.3-0.2-0.1-0.7-0.30.40.2
Short access day 10 total locomotion1.12.04.6-1.7-1.31.4-1.9-2.00.10.2-2.1-0.91.31.2
Short access total locomotion0.20.30.8-0.7-0.40.9-0.5-0.5-0.00.0-0.8-0.50.50.4
One hour access (0.3 mA shock)0.20.20.40.30.3-0.40.60.30.50.6-0.2-0.10.40.6
Compulsive drug intake0.00.00.1-0.1-0.00.2-0.1-0.0-0.3-0.30.2-0.0-0.4-0.2
One hour access (shock baseline)0.00.10.2-0.2-0.20.30.0-0.20.10.2-0.40.30.30.3
Social response proportion0.70.81.4-1.0-0.91.0-1.1-1.2-1.0-1.1-0.11.0-0.6-0.7
Social responses6.17.913.0-3.6-3.43.5-3.4-3.5-3.1-3.1-0.91.5-1.4-1.5
Social time0.81.12.21.31.3-1.51.00.91.31.30.1-0.60.70.7
Soleus weight3.811.120.74.64.5-4.44.44.33.13.02.1-1.00.70.7
Bone: stiffness2.43.98.62.62.7-1.72.92.90.90.82.31.0-0.7-0.8
Tibialis anterior weight0.82.85.52.32.2-2.32.12.11.61.51.1-0.70.40.3
Time to tail flick, vehicle, before self-admin1.11.22.1-1.1-1.21.5-0.9-0.8-1.4-1.40.4-0.5-1.2-0.9
Time to tail flick, vehicle, after self-admin0.81.02.5-0.6-0.7-0.1-1.3-1.30.70.7-1.6-0.81.31.2
Time to tail flick, test, before self-admin1.31.42.3-0.8-1.01.3-0.4-0.3-1.5-1.50.81.5-1.3-1.4
Time to tail flick, test, after self-admin0.20.20.40.00.10.30.30.2-0.4-0.50.60.2-0.6-0.6
Delta time to tail flick, vehicle, before/after SA1.91.83.71.11.0-1.90.30.21.91.9-1.0-0.61.71.6
Delta time to tail flick, test, before/after SA0.91.02.90.10.2-0.7-0.3-0.41.01.0-1.1-1.71.21.3
Tibia length0.61.63.7-1.7-1.81.1-1.9-1.8-0.7-0.7-1.3-0.00.20.2
Ambulatory time before self-admin0.20.30.6-0.8-0.60.6-0.6-0.7-0.5-0.5-0.4-0.2-0.10.1
Ambulatory time after self-admin0.00.00.00.00.2-0.10.1-0.1-0.0-0.10.1-0.2-0.1-0.1
Bone: tissue strength3.23.37.12.42.6-1.82.72.71.11.11.80.3-0.3-0.3
Total heroin consumption1.51.72.9-1.7-1.71.6-1.5-1.6-1.5-1.5-0.30.6-0.8-0.7
Bone: trabecular number1.01.73.0-0.7-0.71.3-0.3-0.3-1.7-1.71.11.6-1.7-1.7
Bone: trabecular spacing2.33.06.30.40.3-1.2-0.3-0.32.12.1-2.1-2.42.52.5
Bone: trabecular thickness4.55.611.90.20.31.01.21.3-2.4-2.53.33.5-3.4-3.4
Bone: trabecular tissue density3.34.88.02.82.8-2.82.62.52.52.40.6-1.21.21.2
Water consumed over 24 hours0.50.71.60.91.0-0.61.01.2-0.1-0.11.30.8-0.8-0.7
Number of responses in last shaping day1.31.42.8-1.7-1.41.7-1.5-1.5-0.6-0.4-1.4-0.60.50.4