LOC120093158

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC120093158 0.1 0.07 9.8e-06 0.02 0.03 0.03 0.02 5.9e-03 1.4e-03 9.4e-04 2.4e-03
2 pVTA gene expression LOC120093158 0.06 0.05 5.5e-03 0.05 0.05 0.05 0.05 3.9e-03 2.9e-03 2.8e-03 2.8e-03
3 NAcc gene expression LOC120093158 0.02 0.02 9.8e-03 0 0.01 0 0 2.8e-01 5.5e-02 2.3e-01 2.6e-01
4 Adipose mRNA stability LOC120093158 0.19 0.1 0.0e+00 0.1 0.12 0.11 0.12 3.0e-11 5.0e-13 1.3e-12 7.9e-13
5 Liver intron excision ratio chr2_91551040_91553236 0.5 0.15 0.0e+00 0.34 0.34 0.35 0.34 2.5e-39 2.0e-38 5.8e-40 1.2e-39
6 BLA gene expression LOC120093158 0.18 0.11 1.8e-06 0.08 0.06 0.07 0.04 7.1e-05 4.8e-04 1.2e-04 4.0e-03
7 Liver intron excision ratio chr2_91503212_91511657 0.66 0.12 0.0e+00 0.46 0.45 0.45 0.46 2.2e-56 7.5e-55 6.0e-55 1.5e-56
8 Eye intron excision ratio chr2_91551040_91553236 0.74 0.14 1.1e-08 0.35 0.36 0.28 0.38 2.7e-06 1.3e-06 3.3e-05 6.6e-07
9 Liver mRNA stability LOC120093158 0.57 0.15 0.0e+00 0.39 0.38 0.39 0.39 4.1e-46 1.1e-44 2.1e-45 3.2e-46
10 Eye mRNA stability LOC120093158 0.59 0.18 3.3e-06 0.3 0.31 0.3 0.34 1.4e-05 1.1e-05 1.6e-05 3.6e-06
11 Eye intron excision ratio chr2_91500640_91511657 0.81 0.11 5.2e-10 0.39 0.37 0.34 0.41 4.1e-07 9.8e-07 3.5e-06 2.0e-07
12 Liver intron excision ratio chr2_91549276_91550868 0.47 0.15 0.0e+00 0.32 0.31 0.32 0.32 5.9e-36 4.5e-35 5.1e-36 6.8e-36
13 Eye intron excision ratio chr2_91500640_91541688 0.27 0.17 7.7e-03 0.13 0.08 0.08 0.1 5.2e-03 2.3e-02 2.3e-02 1.1e-02
14 Adipose gene expression LOC120093158 0.37 0.17 0.0e+00 0.22 0.21 0.21 0.22 4.1e-24 4.5e-23 3.1e-23 3.4e-24
15 Eye intron excision ratio chr2_91549276_91550868 0.75 0.14 2.9e-08 0.4 0.37 0.31 0.39 3.7e-07 1.2e-06 9.4e-06 5.4e-07
16 Liver gene expression LOC120093158 0.78 0.09 0.0e+00 0.54 0.53 0.53 0.54 5.7e-71 4.4e-69 9.5e-70 1.5e-70
17 Liver intron excision ratio chr2_91503212_91549156 0.47 0.18 0.0e+00 0.28 0.26 0.28 0.27 7.6e-31 1.5e-28 1.4e-30 1.9e-30
18 Eye intron excision ratio chr2_91500640_91549156 0.74 0.14 7.9e-08 0.35 0.36 0.31 0.37 2.5e-06 1.4e-06 1.3e-05 1.1e-06
19 PL gene expression LOC120093158 0.06 0.04 2.5e-05 0.02 0.01 0.01 0.01 2.5e-03 1.5e-02 1.6e-02 1.8e-02
20 Eye gene expression LOC120093158 0.91 0.06 7.2e-14 0.44 0.45 0.45 0.45 5.9e-08 2.7e-08 3.0e-08 2.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density2.23.63.9-1.91.61.8-1.8-1.9-1.9-2.02.0-1.9-1.9-2.0-1.9-2.0-2.0-2.02.0-2.01.9-1.9-1.9
Area under the delay curve1.41.51.71.2-1.1-1.21.31.31.21.2-1.21.21.31.21.21.21.21.2-1.21.2-1.21.31.3
BMI with tail0.72.47.12.0-2.7-2.22.21.91.21.5-1.21.31.31.01.51.21.31.3-1.31.3-1.01.41.0
BMI without tail3.16.410.93.1-3.3-3.13.12.82.22.5-2.32.32.22.22.52.32.42.4-2.42.4-2.02.32.0
Body weight0.20.72.41.2-1.5-1.31.21.10.60.8-0.60.60.60.40.70.60.60.6-0.60.6-0.30.50.1
Weight adjusted by age0.10.10.50.5-0.6-0.30.3-0.0-0.3-0.30.2-0.3-0.2-0.2-0.1-0.3-0.4-0.40.4-0.40.30.70.2
Bone surface5.39.310.6-2.72.32.6-2.6-2.9-3.2-3.13.2-3.2-3.2-3.2-3.1-3.2-3.2-3.23.2-3.23.3-3.1-3.2
Bone volume5.18.710.1-2.62.02.5-2.5-2.8-3.0-3.03.1-3.1-3.2-3.1-3.0-3.1-3.1-3.13.1-3.13.2-3.0-3.0
Breakpoint value in progressive ratio session0.70.81.81.2-1.4-1.21.21.00.70.8-0.70.70.70.70.90.70.70.7-0.70.7-0.60.80.6
Number of licking bursts0.70.81.0-0.80.60.9-0.9-1.0-1.0-0.91.0-0.9-0.9-1.0-0.9-1.0-0.9-0.90.9-0.91.0-0.9-0.8
Context. condit. distance diff. score0.30.40.70.3-0.0-0.30.30.50.80.6-0.70.70.70.70.50.80.70.7-0.70.7-0.80.60.4
Locomotion velocity, session 12.02.22.91.7-1.7-1.71.71.71.31.5-1.41.41.41.41.51.41.41.4-1.41.4-1.31.31.2
Locomotion distance, session 10.30.31.20.9-1.1-0.90.90.80.20.5-0.50.30.40.40.50.50.40.4-0.40.4-0.30.40.2
Locomotion velocity, session 21.41.62.91.6-1.7-1.61.61.51.01.2-1.21.11.21.11.31.11.11.1-1.11.1-1.11.21.1
Locomotion distance, session 20.20.21.70.9-1.3-1.00.90.6-0.10.2-0.1-0.00.1-0.00.30.0-0.0-0.00.0-0.00.10.1-0.0
Locomotion velocity, session 30.00.00.10.1-0.0-0.10.10.20.10.2-0.30.20.30.30.20.30.20.2-0.20.2-0.30.30.3
Locomotion distance, session 30.50.50.7-0.60.50.6-0.6-0.7-0.7-0.80.7-0.8-0.7-0.7-0.7-0.7-0.8-0.80.8-0.80.8-0.7-0.8
Stereotopy head waving bouts, day 30.20.20.4-0.0-0.20.0-0.0-0.2-0.5-0.40.5-0.5-0.6-0.5-0.4-0.5-0.5-0.50.5-0.50.6-0.4-0.7
Stereotopy head waving duration, day 30.20.30.60.7-0.8-0.70.70.60.50.5-0.50.50.40.40.50.50.50.5-0.50.5-0.40.40.3
Locomotion velocity, session 79.110.011.9-2.92.42.8-2.8-3.0-3.2-3.23.3-3.2-3.2-3.4-3.2-3.3-3.3-3.33.3-3.33.3-3.4-3.4
Locomotion distance, session 75.06.47.0-2.62.52.6-2.6-2.5-2.5-2.52.5-2.5-2.5-2.5-2.5-2.5-2.5-2.52.5-2.52.4-2.6-2.5
Stereotopy head waving bouts, day 70.10.10.60.6-0.8-0.60.60.40.30.3-0.20.30.30.20.30.20.20.2-0.20.2-0.10.30.1
Stereotopy head waving duration, day 71.11.31.61.3-1.2-1.21.21.21.21.1-1.11.11.11.11.11.11.11.1-1.11.1-1.11.11.0
Locomotion velocity, session 83.84.55.72.4-2.2-2.32.32.32.22.1-2.12.12.12.02.12.12.02.0-2.02.0-2.02.21.8
Locomotion distance, session 80.71.01.61.2-1.2-1.21.21.20.90.9-1.00.91.00.91.01.00.90.9-0.90.9-0.90.90.6
Degree of sensitization distance0.40.40.7-0.60.60.7-0.7-0.6-0.8-0.60.7-0.7-0.6-0.7-0.7-0.7-0.6-0.60.6-0.60.6-0.7-0.6
Degree of sensitization stereotypy1.41.52.11.5-1.5-1.41.41.31.21.2-1.21.21.21.11.21.21.21.2-1.21.2-1.11.21.1
Conditioned locomotion0.10.20.20.4-0.5-0.50.50.50.30.4-0.40.30.40.40.40.40.40.4-0.40.4-0.40.30.4
Cocaine response after cond. corrected0.50.61.1-0.91.01.0-1.0-0.9-0.6-0.80.7-0.7-0.7-0.6-0.8-0.7-0.7-0.70.7-0.70.6-0.7-0.6
Cocaine response after cond. not corrected1.21.31.8-1.31.31.3-1.3-1.3-1.0-1.21.1-1.1-1.1-1.0-1.1-1.1-1.1-1.11.1-1.11.0-1.0-0.9
Cocaine response before conditioning0.60.70.9-0.70.40.6-0.6-0.8-0.9-0.90.9-0.9-0.9-0.9-0.8-0.9-0.9-0.90.9-0.90.9-0.7-0.7
Saline control response2.93.84.5-1.61.21.5-1.5-1.7-2.1-2.02.1-2.1-2.0-2.1-1.9-2.1-2.1-2.12.1-2.12.1-1.9-2.1
Bone: connectivity density2.13.33.8-1.91.91.9-1.9-1.8-1.7-1.81.8-1.8-1.7-1.8-1.8-1.8-1.8-1.81.8-1.81.7-1.8-1.8
Bone: cortical apparent density1.52.02.81.2-1.0-1.31.31.51.71.5-1.41.61.41.41.41.51.51.5-1.51.5-1.41.31.2
Bone: cortical area0.61.01.5-0.50.00.5-0.5-0.8-1.2-1.01.1-1.1-1.0-1.1-1.0-1.1-1.1-1.11.1-1.11.2-1.1-1.0
Bone: cortical porosity0.30.30.5-0.2-0.10.2-0.2-0.4-0.7-0.60.6-0.6-0.6-0.6-0.5-0.6-0.6-0.60.6-0.60.7-0.5-0.6
Bone: cortical porosity0.10.10.3-0.0-0.3-0.00.0-0.2-0.5-0.40.4-0.5-0.4-0.4-0.3-0.4-0.4-0.40.4-0.40.5-0.3-0.3
Bone: cortical thickness0.10.20.40.2-0.6-0.30.2-0.1-0.5-0.30.4-0.4-0.3-0.5-0.3-0.4-0.4-0.40.4-0.40.5-0.4-0.4
Bone: cortical thickness1.82.15.12.0-2.3-1.91.91.51.21.2-1.21.21.31.21.41.11.11.1-1.11.1-1.11.51.4
Bone: cortical tissue density1.62.13.01.2-1.0-1.31.31.51.71.6-1.51.61.51.51.51.51.51.5-1.51.5-1.51.31.2
Condit. Reinf. active minus inactive responses0.70.85.21.7-2.3-1.71.71.10.20.3-0.30.10.30.10.70.20.10.1-0.10.10.10.60.3
Condit. Reinf. active-inactive response ratio1.21.36.72.1-2.6-2.12.11.40.50.7-0.60.50.60.41.00.50.40.4-0.40.4-0.20.80.5
Condit. Reinf. active responses0.50.64.11.5-2.0-1.41.40.7-0.30.10.0-0.2-0.1-0.20.3-0.1-0.2-0.20.2-0.20.40.3-0.0
Condit. Reinf. inactive responses0.00.00.10.1-0.2-0.10.1-0.1-0.4-0.10.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.20.2-0.1-0.2
Incentive salience index mean0.80.95.61.8-2.4-1.81.81.20.10.4-0.30.10.30.10.70.20.10.1-0.10.10.00.70.3
Condit. Reinf. lever presses0.50.62.61.3-1.6-1.41.41.00.30.6-0.40.40.50.30.70.40.40.4-0.40.4-0.20.70.4
Condit. Reinf. active minus inactive responses5.97.38.7-2.21.82.2-2.2-2.5-2.9-2.72.8-2.9-2.8-2.9-2.8-2.8-2.8-2.82.8-2.82.9-2.8-2.9
Condit. Reinf. active-inactive response ratio3.63.74.7-1.51.11.5-1.5-1.8-2.1-2.02.0-2.1-2.1-2.1-2.0-2.1-2.0-2.02.0-2.02.2-2.0-2.2
Condit. Reinf. active responses7.310.212.8-2.62.12.6-2.7-3.0-3.6-3.33.3-3.4-3.3-3.4-3.3-3.3-3.3-3.33.3-3.33.4-3.2-3.4
Condit. Reinf. inactive responses0.70.91.5-0.70.60.7-0.7-0.9-1.2-1.01.0-1.1-0.9-1.0-1.0-1.0-1.0-1.01.0-1.01.0-0.9-1.0
Condit. Reinf. lever presses3.14.25.3-1.71.31.7-1.7-1.9-2.3-2.12.2-2.2-2.1-2.2-2.1-2.2-2.1-2.12.1-2.12.2-2.2-2.2
Condit. Reinf. lever reinforcers received7.610.813.8-2.82.22.8-2.8-3.1-3.7-3.43.4-3.5-3.4-3.5-3.3-3.4-3.4-3.43.4-3.43.5-3.3-3.4
Conditioned reinforcement - actives3.73.76.3-2.52.32.1-2.1-1.9-1.7-1.71.8-1.7-1.8-1.9-1.9-1.7-1.7-1.71.7-1.71.8-2.2-2.1
Conditioned reinforcement - inactives0.20.30.4-0.50.50.3-0.3-0.5-0.5-0.50.5-0.5-0.6-0.6-0.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5
Conditioned locomotion2.32.85.1-2.32.11.8-1.8-1.6-1.5-1.51.6-1.5-1.5-1.6-1.7-1.5-1.5-1.51.5-1.51.5-1.9-2.1
Patch foraging indifference point 0 sec0.20.30.8-0.90.90.9-0.9-0.7-0.4-0.60.4-0.5-0.5-0.4-0.5-0.4-0.5-0.50.5-0.50.3-0.3-0.2
Patch foraging indifference point AUC0.70.81.61.0-0.9-0.91.00.80.80.8-0.90.80.80.90.90.80.80.8-0.80.8-0.91.31.0
Delay disc. indifference point, 0s delay0.10.10.2-0.00.10.0-0.00.20.30.3-0.30.30.40.40.20.40.40.4-0.40.4-0.40.10.1
Delay disc. indifference point, 16s delay1.51.52.01.3-1.2-1.31.31.31.21.2-1.21.21.21.21.31.21.21.2-1.21.2-1.21.41.3
Delay disc. indifference point, 2s delay0.10.10.30.3-0.5-0.40.40.3-0.10.00.1-0.10.0-0.2-0.1-0.1-0.1-0.10.1-0.10.2-0.2-0.5
Delay disc. indifference point, 24s delay0.20.20.50.4-0.2-0.40.40.40.40.4-0.40.40.40.40.50.40.40.4-0.40.4-0.40.70.6
Delay disc. indifference point, 4s delay2.52.63.41.8-1.7-1.61.71.61.61.6-1.61.61.71.61.61.61.61.6-1.61.6-1.61.81.5
Delay disc. indifference point, 8s delay0.40.51.10.5-0.4-0.50.50.50.60.6-0.70.60.80.70.70.60.60.6-0.60.6-0.81.01.0
Indifference point function ln k0.30.40.60.2-0.2-0.30.30.60.70.7-0.70.70.70.60.60.80.70.7-0.70.7-0.70.10.4
Indifference point function log k0.30.40.60.2-0.2-0.30.30.60.70.7-0.70.70.70.60.60.80.70.7-0.70.7-0.70.10.4
Patch foraging total patch changes 0 sec0.00.10.2-0.40.50.4-0.4-0.20.0-0.1-0.0-0.0-0.00.1-0.00.0-0.0-0.00.0-0.0-0.10.10.3
Patch foraging total patch changes 12 sec0.00.10.2-0.30.50.4-0.3-0.3-0.1-0.30.1-0.2-0.10.1-0.1-0.1-0.2-0.20.2-0.2-0.10.40.2
Patch foraging total patch changes 18 sec0.81.01.81.1-1.3-1.01.10.90.90.9-0.90.90.81.01.00.80.90.9-0.90.9-0.91.31.2
Patch foraging total patch changes 24 sec0.40.50.90.1-0.1-0.20.20.51.00.8-0.80.90.70.80.60.90.80.8-0.80.8-0.80.70.6
Patch foraging total patch changes 6 sec0.20.40.90.5-0.4-0.40.40.40.60.5-0.60.60.50.70.60.60.60.6-0.60.6-0.71.00.9
Patch foraging time to switch 0 sec0.20.31.50.9-1.2-0.90.90.60.20.4-0.20.30.10.10.20.20.20.2-0.20.20.00.1-0.3
Patch foraging water rate 0 sec0.10.20.80.20.1-0.10.10.20.30.3-0.40.30.50.50.50.30.30.3-0.30.3-0.60.70.9
Patch foraging water rate 12 sec0.71.01.8-1.21.31.3-1.3-1.2-1.0-1.00.9-0.9-1.0-0.9-1.0-0.9-0.9-0.90.9-0.90.9-1.0-0.7
Patch foraging water rate 18 sec0.40.61.3-0.91.10.9-0.9-0.7-0.6-0.70.7-0.6-0.7-0.8-0.7-0.6-0.6-0.60.6-0.60.7-0.8-0.7
Patch foraging water rate 24 sec0.50.71.00.10.3-0.30.30.71.00.9-0.91.00.90.90.91.01.01.0-1.01.0-1.00.60.8
Patch foraging water rate 6 sec1.31.93.4-1.81.91.7-1.7-1.5-1.3-1.31.3-1.3-1.2-1.3-1.3-1.3-1.2-1.21.2-1.21.2-1.2-1.1
Seeking ratio, delayed vs. immediate footshock6.87.810.6-3.13.33.2-3.2-3.1-2.7-2.92.7-2.8-2.6-2.6-2.8-2.7-2.7-2.72.7-2.72.4-2.4-2.1
Distance traveled before self-admin0.10.10.2-0.20.30.1-0.20.10.20.2-0.20.20.30.2-0.00.20.20.2-0.20.2-0.3-0.5-0.3
Distance traveled after self-admin0.10.10.20.20.0-0.00.10.20.40.3-0.40.40.50.30.30.40.30.3-0.30.3-0.40.30.4
Extensor digitorum longus weight7.027.740.26.3-6.3-6.36.35.94.95.3-5.05.05.14.85.24.94.94.9-4.94.9-4.65.04.0
Bone: elastic displacement0.40.50.9-0.2-0.10.2-0.2-0.5-0.7-0.70.8-0.7-0.7-0.9-0.7-0.8-0.8-0.80.8-0.80.9-0.8-0.9
Bone: elastic work0.70.91.3-0.50.10.5-0.5-0.7-1.1-0.91.0-1.1-0.9-1.1-0.9-1.0-1.0-1.01.0-1.01.1-1.1-1.1
Bone: endosteal estimation2.04.35.4-1.71.21.6-1.6-1.9-2.3-2.12.2-2.2-2.2-2.3-2.1-2.2-2.1-2.12.1-2.12.3-2.3-2.3
Bone: endosteal perimeter1.02.02.4-1.31.21.3-1.3-1.4-1.5-1.41.4-1.5-1.4-1.5-1.5-1.4-1.4-1.41.4-1.41.5-1.5-1.4
Epididymis fat weight0.61.42.10.4-0.1-0.50.51.11.41.4-1.31.41.41.31.21.41.41.4-1.41.4-1.40.71.1
Delta time in closed arm before/after self-admin0.10.10.2-0.30.40.2-0.20.10.30.1-0.20.20.30.20.20.30.20.2-0.20.2-0.2-0.10.1
Delta time in open arm before/after self-admin0.00.00.10.00.00.1-0.1-0.2-0.2-0.10.0-0.1-0.20.0-0.2-0.1-0.1-0.10.1-0.1-0.00.30.1
Diff in mean of infusions in LGA sessions0.40.52.01.1-1.4-1.21.20.90.40.5-0.50.40.40.30.70.50.30.3-0.30.3-0.20.50.3
Delay discount exponential model param0.91.01.2-1.00.91.0-1.1-1.0-0.9-1.01.0-1.0-1.1-0.9-1.0-1.0-1.0-1.01.0-1.01.0-1.1-1.1
Extinction: sum of active levers before priming0.50.51.11.1-1.0-1.01.00.70.60.5-0.60.50.70.50.70.50.40.4-0.40.4-0.50.70.7
Active lever presses in extinction session 60.20.20.5-0.70.60.6-0.6-0.5-0.4-0.40.4-0.4-0.5-0.3-0.5-0.4-0.4-0.40.4-0.40.3-0.7-0.5
Bone: final force0.40.61.0-0.3-0.10.3-0.3-0.6-0.9-0.80.9-0.9-0.9-1.0-0.7-0.9-0.9-0.90.9-0.91.0-0.9-0.8
Bone: final moment0.71.11.5-0.70.30.7-0.7-0.9-1.2-1.11.1-1.1-1.1-1.2-1.1-1.1-1.1-1.11.1-1.11.2-1.2-1.1
Food consumed during 24 hour testing period0.91.12.41.5-1.5-1.41.41.10.91.0-0.90.90.90.81.00.80.90.9-0.90.9-0.81.10.8
Glucose0.71.12.61.5-1.6-1.41.41.11.00.9-0.90.90.90.91.00.90.90.9-0.90.9-0.81.10.9
Heart weight0.50.72.0-1.31.41.3-1.3-0.9-0.7-0.60.7-0.6-0.6-0.7-0.8-0.5-0.5-0.50.5-0.50.6-0.9-0.7
Delay discount hyperbolic model param1.31.31.5-1.21.11.2-1.2-1.2-1.1-1.21.1-1.1-1.2-1.1-1.2-1.1-1.1-1.11.1-1.11.1-1.2-1.2
Intermittent access intake day 1-15 change1.91.95.8-2.02.42.0-2.0-1.6-1.1-1.21.1-1.1-1.2-1.0-1.2-1.1-1.1-1.11.1-1.10.9-0.9-0.9
Intermittent access intake escalation1.61.64.2-1.72.01.8-1.8-1.5-1.0-1.21.1-1.1-1.2-1.0-1.2-1.0-1.0-1.01.0-1.00.9-0.7-0.8
Intermittent access intake escalation 23.93.85.7-2.22.42.4-2.3-2.3-1.9-2.01.9-1.9-1.9-1.8-2.0-1.9-1.9-1.91.9-1.91.7-1.2-1.4
Intermitt. access day 1 inactive lever presses3.94.25.41.3-0.9-1.51.51.92.32.2-2.32.32.12.32.12.32.32.3-2.32.3-2.31.41.8
Intermitt. access day 15 inactive lever presses1.61.72.90.9-0.4-0.70.70.91.41.2-1.51.41.31.61.41.41.41.4-1.41.4-1.61.51.7
Intermitt. access escalation Index0.20.20.60.4-0.4-0.30.30.30.40.4-0.40.40.30.50.40.40.40.4-0.40.4-0.40.80.4
Intermittent access day 1 total infusions2.73.13.7-1.61.31.6-1.6-1.8-1.9-1.91.9-1.9-1.9-1.9-1.7-1.9-1.9-1.91.9-1.91.9-1.6-1.4
Intermittent access day 15 total infusions6.47.28.8-3.02.93.0-2.9-3.0-2.6-2.82.7-2.6-2.8-2.6-2.6-2.6-2.6-2.62.6-2.62.5-2.2-2.1
Intermittent access terminal intake (last 3 days)6.36.98.8-2.72.52.8-2.8-3.0-2.7-2.82.7-2.7-2.8-2.6-2.6-2.7-2.7-2.72.7-2.72.6-2.1-1.8
Intermittent access total infusions4.14.65.7-2.32.22.3-2.2-2.4-2.1-2.32.2-2.2-2.2-2.1-2.1-2.1-2.1-2.12.1-2.12.1-1.8-1.5
Intermittent access day 1 locomotion0.80.91.2-0.60.40.7-0.7-1.1-1.0-1.11.0-1.0-1.1-1.0-0.8-1.0-1.0-1.01.0-1.01.0-0.7-0.5
Intermittent access day 15 total locomotion1.61.72.1-1.20.91.1-1.1-1.4-1.4-1.51.4-1.4-1.5-1.4-1.3-1.4-1.4-1.41.4-1.41.4-0.8-1.0
Intermittent access total locomotion1.11.21.8-1.00.91.0-1.0-1.3-1.2-1.31.2-1.2-1.3-1.1-1.0-1.2-1.2-1.21.2-1.21.1-0.6-0.5
Intermittent access standard deviation1.01.05.1-1.82.31.7-1.7-1.2-0.5-0.80.6-0.6-0.6-0.5-0.8-0.5-0.5-0.50.5-0.50.4-0.7-0.4
Left kidney weight0.30.71.9-1.21.31.4-1.4-1.2-0.7-0.80.7-0.7-0.6-0.6-0.8-0.6-0.6-0.60.6-0.60.5-0.5-0.4
Right kidney weight0.00.10.4-0.40.50.6-0.6-0.30.10.0-0.10.20.20.20.10.20.20.2-0.20.2-0.30.50.6
Cocaine induced anxiety0.50.61.10.8-0.7-0.60.60.60.70.7-0.80.70.70.90.80.70.70.7-0.70.7-0.81.01.1
Post-drug Anxiety2.73.03.61.5-1.5-1.71.61.91.91.9-1.81.91.71.81.71.91.91.9-1.91.9-1.71.11.3
Baseline Anxiety0.00.00.4-0.2-0.0-0.00.00.2-0.10.10.1-0.0-0.1-0.1-0.2-0.1-0.1-0.10.1-0.10.1-0.3-0.6
Tail length0.41.31.81.3-1.1-1.21.21.21.01.3-1.21.21.11.11.11.21.21.2-1.21.2-1.00.90.8
Length with tail0.00.10.3-0.10.30.2-0.2-0.1-0.2-0.10.1-0.2-0.2-0.2-0.3-0.1-0.1-0.10.1-0.10.2-0.4-0.5
Length without tail1.12.42.9-1.51.51.5-1.6-1.5-1.5-1.51.5-1.5-1.4-1.6-1.6-1.5-1.6-1.61.6-1.61.5-1.6-1.7
Times rat made contact with spout0.10.10.2-0.20.10.3-0.3-0.3-0.1-0.30.3-0.2-0.4-0.2-0.2-0.3-0.3-0.30.3-0.30.3-0.1-0.1
Lifetime Intake3.33.84.9-2.22.12.2-2.1-2.2-1.9-2.01.9-1.9-2.0-1.9-1.9-1.9-1.9-1.91.9-1.91.8-1.6-1.3
Liver weight, left0.60.93.41.5-1.8-1.41.41.00.60.8-0.70.60.80.60.90.60.60.6-0.60.6-0.61.00.9
Liver weight, right0.30.51.10.9-0.9-0.70.80.60.60.6-0.70.60.70.70.80.60.60.6-0.60.6-0.71.01.0
Locomotor activity0.00.00.1-0.10.1-0.00.00.10.30.3-0.30.30.10.30.10.30.30.3-0.30.3-0.30.10.1
Locomotor testing distance0.00.00.0-0.10.20.0-0.1-0.00.00.1-0.00.0-0.10.1-0.2-0.00.00.0-0.00.0-0.10.0-0.2
Locomotor testing rearing0.50.81.2-1.01.11.1-1.1-1.1-0.9-0.90.8-0.9-1.0-0.7-1.0-0.9-0.9-0.90.9-0.90.7-0.6-0.6
Locomotion in novel chamber0.20.31.20.7-1.1-0.90.90.60.40.3-0.40.30.40.30.50.40.30.3-0.30.3-0.30.60.5
Locomotion in novel chamber post-restriction0.00.00.10.10.1-0.10.10.10.20.2-0.20.20.30.20.20.20.20.2-0.20.2-0.30.20.4
Fecal boli incidents, locomotor time 10.10.10.40.5-0.7-0.40.40.20.20.2-0.20.20.20.20.30.20.20.2-0.20.2-0.20.10.3
Change in fecal boli incidents, locomotor task2.32.23.8-1.81.91.6-1.6-1.5-1.5-1.41.4-1.4-1.4-1.3-1.5-1.4-1.4-1.41.4-1.41.3-1.3-1.3
Time >=10cm from walls, locomotor time 12.82.83.2-1.61.41.5-1.5-1.7-1.7-1.81.7-1.7-1.7-1.7-1.7-1.8-1.8-1.81.8-1.81.7-1.7-1.4
Bouts of movement, locomotor time 11.61.82.90.50.0-0.50.50.91.51.3-1.51.51.51.61.31.51.51.5-1.51.5-1.71.31.7
Total resting periods, locomotor time 10.91.01.70.20.2-0.30.30.61.21.0-1.11.11.21.21.01.21.21.2-1.21.2-1.31.01.2
Rest time, locomotor task time 10.30.30.6-0.20.40.1-0.10.30.70.6-0.60.70.60.70.50.70.70.7-0.70.7-0.80.40.6
Distance moved, locomotor task time 10.00.10.1-0.00.20.1-0.1-0.2-0.3-0.20.2-0.3-0.3-0.2-0.2-0.3-0.3-0.30.3-0.30.3-0.2-0.2
Vertical activity count, locomotor time 10.70.71.2-0.40.30.4-0.4-0.6-1.0-0.80.9-0.9-0.9-1.0-0.9-0.9-0.9-0.90.9-0.91.1-1.0-1.1
Time >=10cm from walls, locomotor time 22.32.53.0-1.31.01.2-1.2-1.5-1.7-1.71.7-1.7-1.6-1.7-1.6-1.7-1.7-1.71.7-1.71.7-1.3-1.5
Bouts of movement, locomotor time 22.42.53.81.2-0.7-1.01.11.31.81.6-1.71.71.81.81.61.71.71.7-1.71.7-1.91.61.9
Total resting periods, locomotor time 22.52.74.01.2-0.8-1.11.11.31.81.6-1.81.81.81.91.71.81.81.8-1.81.8-1.91.72.0
Rest time, locomotor task time 20.80.91.30.6-0.6-0.70.70.81.00.9-1.01.01.01.11.01.01.01.0-1.01.0-1.11.01.1
Distance moved, locomotor task time 20.00.00.1-0.00.20.1-0.1-0.00.0-0.0-0.00.00.00.10.00.00.00.0-0.00.0-0.0-0.20.0
Vertical activity count, locomotor time 20.10.10.50.7-0.7-0.60.60.40.10.2-0.10.10.10.00.20.10.10.1-0.10.10.00.20.0
Light reinforcement 11.62.93.71.8-1.8-1.71.71.71.71.7-1.71.71.71.61.81.71.71.7-1.71.7-1.61.81.9
Light reinforcement 22.53.45.12.1-2.3-2.12.12.01.81.8-1.81.81.81.71.91.71.71.7-1.71.7-1.61.71.8
Bone: marrow area1.83.95.0-1.51.11.5-1.5-1.7-2.2-2.02.1-2.1-2.1-2.2-2.0-2.1-2.1-2.12.1-2.12.2-2.2-2.2
Bone: maximum diameter0.40.71.1-0.70.40.7-0.7-0.8-1.0-0.90.8-0.9-0.8-0.8-0.8-0.8-0.8-0.80.8-0.80.8-0.8-0.6
Bone: maximum force0.71.21.8-0.50.00.5-0.5-0.9-1.3-1.11.2-1.2-1.2-1.3-1.0-1.2-1.2-1.21.2-1.21.3-1.2-1.1
Bone: maximum moment1.11.92.6-0.90.50.9-0.9-1.2-1.6-1.41.5-1.5-1.5-1.6-1.4-1.5-1.5-1.51.5-1.51.6-1.6-1.5
Mean time between licks in bursts0.10.10.80.7-0.9-0.70.60.4-0.10.10.0-0.00.0-0.10.1-0.00.00.0-0.00.00.2-0.0-0.3
Mean num. licks in bursts0.40.50.90.5-0.5-0.60.60.70.90.7-0.80.80.60.80.70.70.70.7-0.70.7-0.70.80.7
Cd content in liver3.23.54.31.7-1.2-1.51.51.71.91.9-2.01.92.02.01.92.01.91.9-1.91.9-2.12.12.1
Co content in liver1.31.52.00.7-0.4-0.80.81.11.41.3-1.41.41.31.41.21.41.41.4-1.41.4-1.41.21.1
Cu content in liver2.12.64.5-2.02.12.0-2.0-1.9-1.5-1.61.5-1.5-1.5-1.4-1.6-1.5-1.4-1.41.4-1.41.3-1.4-1.1
Fe content in liver2.42.94.1-1.10.71.1-1.1-1.4-1.9-1.71.8-1.8-1.9-1.9-1.7-1.8-1.9-1.91.9-1.92.0-1.8-2.0
K content in liver0.10.10.9-0.60.90.6-0.6-0.30.0-0.00.00.0-0.00.0-0.20.00.10.1-0.10.1-0.1-0.1-0.2
Mg content in liver0.30.30.6-0.70.80.7-0.7-0.5-0.4-0.40.4-0.4-0.5-0.4-0.5-0.4-0.4-0.40.4-0.40.4-0.6-0.6
Mn content in liver0.30.30.50.7-0.3-0.50.50.60.60.6-0.60.60.60.60.50.60.60.6-0.60.6-0.50.70.3
Na content in liver0.30.31.0-0.91.00.9-0.9-0.7-0.5-0.50.5-0.5-0.5-0.4-0.6-0.5-0.4-0.40.4-0.40.4-0.4-0.4
Rb content in liver0.10.20.30.3-0.3-0.30.30.40.40.5-0.50.50.40.50.40.40.50.5-0.50.5-0.50.40.5
Se content in liver0.00.00.1-0.20.30.2-0.2-0.10.00.2-0.10.10.00.1-0.00.10.20.2-0.20.2-0.10.20.0
Sr content in liver0.40.30.50.7-0.2-0.60.60.70.60.7-0.60.60.60.50.40.60.60.6-0.60.6-0.50.6-0.0
Zn content in liver0.40.51.8-1.11.31.1-1.1-0.8-0.5-0.60.5-0.5-0.5-0.4-0.7-0.5-0.5-0.50.5-0.50.4-0.5-0.5
Bone: minimum diameter1.42.64.3-0.4-0.40.4-0.4-1.1-1.9-1.61.8-1.8-1.7-2.0-1.5-1.8-1.8-1.81.8-1.82.1-1.8-2.0
Time in familiar zone, hab. session 10.10.10.5-0.40.70.3-0.30.00.50.2-0.40.40.40.40.20.40.30.3-0.30.3-0.50.20.2
Time in novel zone, hab. session 10.00.00.10.1-0.3-0.10.1-0.2-0.4-0.20.2-0.3-0.2-0.2-0.1-0.2-0.2-0.20.2-0.20.3-0.00.1
Total zone transitions, hab. session 10.30.41.10.9-1.1-1.01.00.80.30.6-0.50.40.60.40.60.50.50.5-0.50.5-0.40.50.3
Total locomotion distance, hab. session 10.10.20.40.1-0.4-0.20.2-0.1-0.7-0.40.5-0.6-0.4-0.5-0.4-0.5-0.5-0.50.5-0.50.6-0.4-0.6
Locomotion velocity, hab. session 10.10.10.60.5-0.8-0.50.50.2-0.5-0.10.2-0.3-0.2-0.3-0.1-0.2-0.2-0.20.2-0.20.4-0.2-0.4
Time in familiar zone, hab. session 20.20.21.5-0.81.20.7-0.7-0.20.40.2-0.30.40.30.40.10.30.40.4-0.40.4-0.50.10.3
Time in novel zone, hab. session 20.40.40.70.3-0.7-0.20.2-0.3-0.9-0.60.6-0.8-0.6-0.7-0.4-0.7-0.8-0.80.8-0.80.8-0.4-0.5
Total zone transitions, hab. session 20.70.91.20.8-0.7-0.90.91.00.81.0-1.10.91.11.00.91.11.01.0-1.01.0-1.00.90.8
Total locomotion distance, hab. session 20.00.00.20.3-0.5-0.30.30.2-0.20.1-0.1-0.10.10.00.10.10.00.0-0.00.00.00.1-0.0
Locomotion velocity, hab. session 20.00.00.10.2-0.4-0.30.30.2-0.30.1-0.1-0.10.10.10.10.10.00.0-0.00.0-0.00.1-0.0
Novel to familiar place preference ratio0.20.20.4-0.0-0.10.1-0.1-0.3-0.5-0.50.5-0.6-0.4-0.5-0.4-0.5-0.6-0.60.6-0.60.5-0.3-0.3
Novelty place preference0.20.20.3-0.10.10.2-0.2-0.4-0.5-0.50.4-0.6-0.4-0.5-0.4-0.5-0.6-0.60.6-0.60.5-0.2-0.3
Time in novel zone, NPP test0.00.00.10.1-0.10.0-0.0-0.2-0.3-0.30.2-0.3-0.2-0.2-0.1-0.2-0.3-0.30.3-0.30.20.00.0
Total zone transitions, NPP test0.91.31.61.2-1.0-1.21.21.30.91.2-1.21.01.21.11.11.21.11.1-1.11.1-1.11.10.9
Total locomotion distance, NPP test0.00.10.50.5-0.7-0.50.50.2-0.20.0-0.0-0.10.0-0.10.1-0.0-0.1-0.10.1-0.10.10.0-0.1
Locomotion velocity, NPP test0.10.10.30.1-0.3-0.10.1-0.1-0.6-0.40.4-0.5-0.4-0.4-0.3-0.4-0.4-0.40.4-0.40.5-0.4-0.5
Intraocular pressure0.60.92.81.4-1.7-1.51.51.20.80.8-0.80.70.80.60.90.80.60.6-0.60.6-0.50.70.4
Delta distance traveled before/after self-admin0.60.60.8-0.60.60.8-0.8-0.9-0.8-0.90.9-0.9-0.9-0.9-0.7-0.9-0.9-0.90.9-0.90.9-0.3-0.4
Delta ambulatory time before/after self-admin0.91.01.4-0.80.91.1-1.1-1.1-1.1-1.21.1-1.1-1.1-1.0-0.9-1.1-1.1-1.11.1-1.11.0-0.4-0.5
Parametrial fat weight0.51.01.50.7-0.5-0.80.81.01.01.2-1.01.11.11.00.91.11.21.2-1.21.2-1.00.80.7
Pavlov. Cond. lever latency0.10.10.7-0.70.80.7-0.6-0.5-0.1-0.20.2-0.1-0.2-0.1-0.3-0.2-0.1-0.10.1-0.10.1-0.3-0.1
Pavlov. Cond. magazine entry latency0.00.10.40.4-0.6-0.40.40.20.0-0.10.1-0.1-0.1-0.20.1-0.1-0.2-0.20.2-0.20.2-0.1-0.1
Pavlov. Cond. change in total contacts0.80.82.81.4-1.7-1.41.41.10.60.8-0.70.60.60.50.80.60.60.6-0.60.6-0.40.70.5
Pavlov. Cond. index score0.30.41.21.0-1.1-0.90.90.80.50.6-0.50.50.50.50.60.50.50.5-0.50.5-0.40.60.5
Pavlov. Cond. latency score0.30.41.11.0-1.1-0.90.90.80.50.6-0.50.50.60.50.60.50.50.5-0.50.5-0.40.60.5
Pavlov. Cond. lever contacts0.10.10.70.6-0.8-0.60.50.3-0.10.00.1-0.1-0.0-0.20.0-0.1-0.1-0.10.1-0.10.20.0-0.2
Pavlov. Cond. magazine entry number0.40.51.2-1.01.11.0-1.0-0.8-0.7-0.60.6-0.6-0.6-0.6-0.7-0.6-0.5-0.50.5-0.50.5-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.60.70.9-0.90.90.9-0.9-0.9-0.8-0.80.8-0.8-0.8-0.8-0.9-0.8-0.8-0.80.8-0.80.8-0.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.30.41.10.9-1.1-0.90.90.70.50.5-0.50.50.50.40.60.40.40.4-0.40.4-0.40.50.4
Pavlov. Cond. response bias0.10.10.80.7-0.9-0.70.70.40.10.2-0.10.10.10.00.20.10.00.0-0.00.00.00.20.0
Pavlov. Cond. lever latency1.31.82.11.4-1.3-1.41.41.41.41.4-1.41.41.31.31.41.41.31.3-1.31.3-1.31.31.3
Pavlov. Cond. magazine entry latency0.10.10.2-0.1-0.00.2-0.1-0.3-0.4-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.3-0.3-0.2
Pavlov. Cond. change in total contacts1.52.13.3-0.90.50.9-0.9-1.2-1.7-1.41.6-1.6-1.6-1.6-1.5-1.6-1.5-1.51.5-1.51.7-1.5-1.8
Pavlov. Cond. index score1.11.41.9-0.80.50.9-0.9-1.1-1.4-1.21.3-1.3-1.3-1.3-1.2-1.3-1.2-1.21.2-1.21.3-1.3-1.3
Pavlov. Cond. latency score1.01.31.6-0.90.70.9-0.9-1.1-1.3-1.11.2-1.2-1.2-1.2-1.2-1.2-1.1-1.11.1-1.11.2-1.2-1.3
Pavlov. Cond. lever contacts1.11.62.0-1.21.11.2-1.2-1.3-1.4-1.21.3-1.3-1.2-1.3-1.3-1.3-1.2-1.21.2-1.21.2-1.3-1.3
Pavlov. Cond. magazine entry number0.10.10.30.10.0-0.20.20.30.50.4-0.40.40.50.40.40.50.40.4-0.40.4-0.50.40.5
Pavlov. Cond. intertrial magazine entries0.00.00.10.3-0.4-0.30.30.30.10.2-0.10.10.1-0.00.10.10.10.1-0.10.10.0-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.1.11.41.9-0.90.60.9-0.9-1.1-1.4-1.21.3-1.3-1.3-1.3-1.2-1.3-1.2-1.21.2-1.21.3-1.2-1.3
Pavlov. Cond. response bias1.31.82.4-1.00.81.1-1.1-1.3-1.6-1.41.5-1.4-1.4-1.5-1.4-1.5-1.4-1.41.4-1.41.5-1.4-1.5
Time in closed arm before self-admin0.10.10.3-0.40.50.6-0.6-0.4-0.2-0.20.3-0.2-0.3-0.4-0.3-0.2-0.1-0.10.1-0.10.3-0.5-0.2
Time in closed arm after self-admin0.10.10.3-0.20.50.3-0.30.10.50.3-0.30.40.40.30.30.50.40.4-0.40.4-0.4-0.30.3
Time in open arm before self-admin0.80.91.2-0.50.10.4-0.4-0.8-1.1-1.01.0-1.1-0.9-1.1-0.9-1.1-1.1-1.11.1-1.11.1-0.7-1.0
Time in open arm after self-admin0.40.41.41.0-1.1-0.91.00.60.40.5-0.50.40.40.60.50.40.50.5-0.50.5-0.51.20.6
Bone: periosteal estimation1.93.85.4-1.20.61.2-1.2-1.7-2.3-2.02.1-2.2-2.1-2.2-2.0-2.1-2.1-2.12.1-2.12.3-2.2-2.2
Bone: periosteal perimeter1.11.82.4-1.10.81.1-1.1-1.3-1.6-1.41.4-1.5-1.4-1.4-1.4-1.4-1.4-1.41.4-1.41.4-1.4-1.3
Bone: post-yield work2.93.94.9-2.22.12.2-2.2-2.2-2.0-2.01.9-1.9-1.9-1.9-2.0-1.9-1.9-1.91.9-1.91.8-1.9-1.6
Progressive ratio test 1 active lever presses0.50.52.0-1.21.41.2-1.1-1.0-0.5-0.70.5-0.5-0.6-0.4-0.5-0.5-0.5-0.50.5-0.50.3-0.60.2
Progressive ratio test 1 breakpoint0.70.81.9-1.31.41.2-1.2-1.2-0.7-0.90.7-0.7-0.8-0.7-0.6-0.7-0.7-0.70.7-0.70.6-0.80.1
Progressive ratio test 1 inactive lever presses0.30.30.50.1-0.0-0.20.20.30.70.6-0.70.70.40.70.60.70.70.7-0.70.7-0.70.60.7
Progressive ratio test 2 active lever presses2.72.93.9-2.01.91.9-1.9-1.9-1.7-1.81.7-1.7-1.6-1.7-1.7-1.7-1.7-1.71.7-1.71.6-1.6-1.3
Progressive ratio test 2 breakpoint3.03.34.2-2.12.01.9-1.9-1.9-1.8-1.91.9-1.8-1.8-1.9-1.8-1.8-1.8-1.81.8-1.81.8-1.6-1.5
Progressive ratio test 2 inactive lever presses1.51.72.4-1.51.51.4-1.4-1.5-1.3-1.41.3-1.3-1.5-1.3-1.3-1.3-1.3-1.31.3-1.31.3-0.8-0.9
Incentive Sensitization - Responses4.14.24.9-1.71.51.7-1.7-2.0-2.2-2.12.2-2.2-2.0-2.2-2.1-2.2-2.2-2.22.2-2.22.2-1.9-1.9
Incentive Sensitization - Breakpoint3.73.74.3-1.71.51.7-1.7-1.9-2.1-2.02.1-2.1-1.8-2.1-2.0-2.1-2.1-2.12.1-2.12.0-1.7-1.9
Sum of active levers in priming session hrs 5-60.70.70.9-0.70.40.6-0.6-0.7-0.8-0.80.9-0.9-0.8-0.9-0.7-0.8-0.9-0.90.9-0.90.9-1.0-0.9
Progressive ratio0.10.10.5-0.30.50.5-0.5-0.5-0.2-0.30.1-0.20.00.1-0.1-0.2-0.2-0.20.2-0.2-0.2-0.20.7
Food seeking constrained by brief footshock0.70.93.31.3-1.8-1.51.51.20.60.8-0.70.70.60.60.80.60.70.7-0.70.7-0.50.50.3
Seeking ratio, punishment vs. effort0.60.72.11.0-1.4-1.41.41.30.70.9-0.60.70.60.40.70.70.70.7-0.70.7-0.30.5-0.3
Retroperitoneal fat weight0.00.10.2-0.30.40.1-0.10.10.30.3-0.10.30.30.10.10.30.30.3-0.30.3-0.2-0.30.0
Reaction time number correct1.11.62.3-1.20.81.0-1.0-1.1-1.4-1.21.4-1.3-1.3-1.5-1.3-1.3-1.3-1.31.3-1.31.5-1.5-1.5
Reaction time mean minus median3.44.55.52.2-2.0-2.22.22.12.12.1-2.12.12.02.12.22.12.12.1-2.12.1-2.12.22.3
Reaction time mean minus median AUC3.24.25.72.4-2.4-2.32.32.01.92.0-1.91.91.91.92.11.91.91.9-1.91.9-1.82.12.3
Reaction time num false alarms3.34.45.4-1.41.01.7-1.7-2.1-2.3-2.22.3-2.3-2.2-2.3-2.1-2.3-2.3-2.32.3-2.32.3-2.0-2.1
Reaction time num false alarms AUC2.83.84.8-1.41.11.6-1.6-2.0-2.2-2.12.1-2.1-2.0-2.1-2.0-2.1-2.1-2.12.1-2.12.1-1.8-1.9
Reaction time trials correct on left1.11.62.3-1.20.81.0-1.0-1.1-1.4-1.21.4-1.3-1.3-1.5-1.3-1.3-1.3-1.31.3-1.31.5-1.5-1.5
Reaction time trials on left1.01.52.1-1.10.70.9-0.9-1.1-1.4-1.21.3-1.3-1.3-1.5-1.2-1.3-1.2-1.21.2-1.21.4-1.4-1.4
Reaction time mean1.41.93.11.6-1.7-1.71.71.51.41.3-1.31.31.21.31.41.31.31.3-1.31.3-1.21.21.3
Reaction time mean AUC1.31.73.21.6-1.8-1.71.81.41.21.2-1.21.21.11.21.41.21.11.1-1.11.1-1.11.21.2
Median of all reaction times0.71.02.11.2-1.4-1.41.41.10.90.9-0.90.90.80.81.00.80.80.8-0.80.8-0.80.70.7
Reaction time omissions3.85.27.62.8-2.7-2.62.72.31.92.1-2.22.02.22.22.32.02.02.0-2.02.0-2.12.52.4
Reaction time false alarm rate0.30.40.6-0.30.30.6-0.6-0.8-0.7-0.80.7-0.8-0.7-0.6-0.7-0.8-0.8-0.80.8-0.80.6-0.5-0.5
Reaction time premature initiation rate0.50.62.3-1.21.51.2-1.2-0.9-0.6-0.80.7-0.7-0.6-0.6-0.6-0.6-0.7-0.70.7-0.70.5-0.4-0.2
Reaction time premature initiations1.11.63.0-1.61.71.5-1.5-1.4-1.2-1.31.2-1.2-1.2-1.2-1.1-1.1-1.2-1.21.2-1.21.1-1.1-0.9
Std. dev. reaction times2.02.83.71.8-1.7-1.81.81.61.61.6-1.61.61.61.71.71.61.61.6-1.61.6-1.61.81.9
Reaction time trials completed1.01.52.1-1.10.70.9-0.9-1.1-1.4-1.21.3-1.3-1.3-1.5-1.2-1.3-1.2-1.21.2-1.21.4-1.4-1.4
Reaction time trials AUC0.91.42.0-1.00.60.8-0.8-1.0-1.3-1.11.3-1.2-1.3-1.4-1.1-1.2-1.2-1.21.2-1.21.4-1.4-1.4
Run reversals in cocaine runway, females0.70.71.50.7-0.7-1.01.00.90.80.8-0.80.80.90.80.90.80.80.8-0.80.8-0.91.20.7
Run reversals in cocaine runway, males1.11.12.91.6-1.7-1.61.61.20.70.9-0.80.80.90.71.00.70.70.7-0.70.7-0.70.90.8
Latency to leave start box in cocaine runway0.80.91.0-0.91.01.0-1.0-1.0-0.9-1.00.9-1.0-0.9-0.9-0.9-0.9-0.9-0.90.9-0.90.9-0.8-0.8
Latency to leave start box in cocaine runway, F2.93.23.9-1.81.92.0-2.0-2.0-1.8-1.91.8-1.8-1.7-1.7-1.8-1.8-1.8-1.81.8-1.81.7-1.3-1.5
Latency to leave start box in cocaine runway, M1.41.42.11.4-1.3-1.51.41.31.11.2-1.11.11.11.01.21.11.11.1-1.11.1-1.00.81.0
Std. dev. time between licks in bursts0.20.20.5-0.30.30.3-0.3-0.3-0.5-0.40.5-0.5-0.4-0.5-0.5-0.5-0.5-0.50.5-0.50.5-0.7-0.7
Total sessions with >9 infusions0.20.20.5-0.60.70.6-0.6-0.7-0.3-0.50.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.2-0.20.2
Short access day 1 total inactive lever presses0.00.00.2-0.30.40.3-0.3-0.20.20.1-0.10.20.00.20.10.20.20.2-0.20.2-0.2-0.10.3
Short access day 10 total inactive lever presses1.82.02.80.6-0.1-0.70.71.21.71.6-1.61.71.51.61.41.71.71.7-1.71.7-1.70.91.2
Short access day 1 total infusions0.70.72.0-1.41.31.2-1.2-1.0-0.6-0.80.7-0.7-0.6-0.6-0.6-0.6-0.6-0.60.6-0.60.5-1.0-0.2
Short access day 10 total infusions1.21.42.2-1.41.41.5-1.4-1.5-1.1-1.31.1-1.1-1.1-1.0-1.1-1.1-1.1-1.11.1-1.10.9-0.8-0.5
Short access total infusions1.61.82.7-1.71.51.6-1.6-1.6-1.3-1.41.3-1.3-1.3-1.2-1.2-1.3-1.3-1.31.3-1.31.2-1.1-0.7
Short access day 1 locomotion0.00.00.3-0.10.00.1-0.1-0.10.1-0.0-0.10.10.00.20.20.10.10.1-0.10.1-0.20.30.5
Short access day 10 total locomotion1.51.72.31.3-1.2-1.31.31.21.31.2-1.31.31.21.31.41.31.31.3-1.31.3-1.31.51.4
Short access total locomotion0.10.20.4-0.40.30.5-0.4-0.6-0.4-0.50.4-0.4-0.5-0.3-0.3-0.4-0.4-0.40.4-0.40.4-0.3-0.0
One hour access (0.3 mA shock)5.56.48.4-2.92.92.7-2.7-2.7-2.4-2.52.5-2.4-2.5-2.5-2.5-2.4-2.4-2.42.4-2.42.4-2.3-2.3
Compulsive drug intake1.51.52.01.0-0.8-1.21.21.41.31.4-1.21.31.41.11.21.31.31.3-1.31.3-1.20.60.7
One hour access (shock baseline)7.48.510.8-3.13.03.2-3.1-3.3-2.9-3.12.9-2.9-3.1-2.8-2.9-2.9-2.9-2.92.9-2.92.8-2.3-2.3
Social response proportion0.50.50.90.5-0.4-0.60.60.70.70.8-0.80.70.70.90.70.80.80.8-0.80.8-0.90.90.8
Social responses1.21.62.11.1-1.1-1.21.21.21.11.3-1.41.21.21.51.21.31.31.3-1.31.3-1.41.41.4
Social time0.20.20.4-0.20.10.2-0.2-0.5-0.6-0.50.5-0.6-0.7-0.5-0.5-0.6-0.6-0.60.6-0.60.5-0.1-0.3
Soleus weight0.51.43.01.6-1.7-1.51.51.31.01.1-1.11.01.11.01.21.01.01.0-1.01.0-0.91.21.1
Bone: stiffness0.20.30.4-0.1-0.10.1-0.1-0.4-0.6-0.60.6-0.6-0.6-0.6-0.5-0.6-0.6-0.60.6-0.60.7-0.5-0.4
Tibialis anterior weight4.114.026.04.9-5.1-4.94.84.33.33.7-3.43.43.53.23.63.33.33.3-3.33.3-3.03.52.6
Time to tail flick, vehicle, before self-admin0.90.92.0-1.41.21.1-1.1-0.8-0.7-0.80.7-0.8-0.8-0.7-0.9-0.7-0.8-0.80.8-0.80.7-1.4-1.3
Time to tail flick, vehicle, after self-admin2.12.33.9-2.01.91.7-1.8-1.5-1.3-1.31.3-1.3-1.4-1.3-1.5-1.3-1.3-1.31.3-1.31.3-2.0-1.7
Time to tail flick, test, before self-admin0.80.81.10.6-0.2-0.40.50.60.91.0-0.91.00.91.00.80.91.11.1-1.11.1-1.00.81.0
Time to tail flick, test, after self-admin0.30.30.5-0.50.60.7-0.6-0.7-0.6-0.60.5-0.5-0.5-0.4-0.4-0.6-0.5-0.50.5-0.50.4-0.3-0.0
Delta time to tail flick, vehicle, before/after SA1.41.41.8-1.21.21.2-1.2-1.2-1.2-1.11.3-1.2-1.2-1.3-1.2-1.2-1.1-1.11.1-1.11.2-1.3-1.1
Delta time to tail flick, test, before/after SA0.00.00.20.1-0.2-0.10.10.00.1-0.0-0.10.10.20.20.20.10.00.0-0.00.0-0.20.30.4
Tibia length0.72.04.5-2.02.11.9-1.9-1.6-1.2-1.31.2-1.2-1.3-1.1-1.4-1.1-1.1-1.11.1-1.11.1-1.6-1.2
Ambulatory time before self-admin0.10.10.3-0.20.3-0.00.00.20.30.3-0.30.30.50.20.10.40.30.3-0.30.3-0.4-0.6-0.2
Ambulatory time after self-admin0.30.30.4-0.30.50.6-0.6-0.6-0.5-0.70.6-0.6-0.5-0.5-0.5-0.6-0.6-0.60.6-0.60.5-0.3-0.3
Bone: tissue strength1.51.52.4-1.31.61.5-1.4-1.5-1.3-1.31.2-1.2-1.0-1.1-1.2-1.2-1.2-1.21.2-1.21.0-0.8-0.7
Total heroin consumption0.00.10.2-0.0-0.1-0.10.1-0.1-0.3-0.20.3-0.2-0.3-0.3-0.2-0.2-0.2-0.20.2-0.20.4-0.2-0.4
Bone: trabecular number1.11.71.8-1.31.11.3-1.3-1.3-1.3-1.31.3-1.3-1.3-1.3-1.3-1.3-1.3-1.31.3-1.31.3-1.3-1.2
Bone: trabecular spacing1.92.52.71.6-1.4-1.51.51.61.41.6-1.61.51.61.61.61.61.61.6-1.61.6-1.61.61.6
Bone: trabecular thickness3.64.35.2-2.01.61.9-1.9-2.0-1.9-2.12.1-2.0-2.2-2.1-2.1-2.1-2.1-2.12.1-2.12.2-2.3-2.1
Bone: trabecular tissue density2.94.14.92.2-2.2-2.12.12.02.02.0-2.02.01.92.02.11.91.91.9-1.91.9-1.92.12.1
Water consumed over 24 hours0.00.00.20.3-0.4-0.30.30.20.20.2-0.10.20.10.20.20.10.20.2-0.20.2-0.10.20.2
Number of responses in last shaping day0.10.10.5-0.1-0.2-0.00.10.00.20.1-0.20.10.10.20.30.20.20.2-0.20.2-0.20.70.5