Hub : Genes

LOC120093158

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120093158 0.15 0.09 2.3e-11 0.1 0.13 0.14 0.13 3.4e-08 2.6e-10 5.5e-11 9.9e-11
2 Brain gene expression LOC120093158 0.11 0.09 1.8e-05 0.02 0.02 0.02 0.02 3.8e-03 9.6e-03 4.3e-03 4.1e-03
3 Adipose mRNA stability LOC120093158 0.13 0.08 2.5e-13 0.09 0.08 0.08 0.08 1.2e-09 3.7e-09 5.8e-09 3.3e-09
4 NAcc gene expression LOC120093158 0.03 0.02 3.2e-05 0.02 0.02 0.02 0.01 1.1e-03 3.1e-04 2.1e-04 2.0e-03
5 Eye intron excision ratio chr2_93458436_93460630 0.73 0.15 3.1e-08 0.35 0.36 0.39 0.41 2.2e-06 1.8e-06 4.5e-07 2.2e-07
6 Eye intron excision ratio chr2_93408057_93419071 0.81 0.11 7.5e-10 0.41 0.36 0.35 0.42 2.1e-07 1.8e-06 2.2e-06 1.2e-07
7 Eye intron excision ratio chr2_93408057_93456552 0.72 0.15 2.5e-07 0.29 0.34 0.33 0.35 2.3e-05 3.9e-06 4.6e-06 2.5e-06
8 Liver mRNA stability LOC120093158 0.55 0.15 0.0e+00 0.37 0.36 0.37 0.37 1.3e-42 2.7e-42 3.3e-43 1.8e-43
9 Liver gene expression LOC120093158 0.77 0.1 0.0e+00 0.52 0.52 0.53 0.53 7.5e-68 1.4e-66 9.7e-69 3.1e-69
10 Eye intron excision ratio chr2_93408057_93449086 0.26 0.17 8.8e-03 0.12 0.07 0.05 0.08 6.7e-03 3.5e-02 6.6e-02 2.2e-02
11 Liver intron excision ratio chr2_93410626_93419071 0.66 0.13 0.0e+00 0.45 0.45 0.45 0.46 8.7e-56 4.5e-55 7.6e-56 4.5e-57
12 Liver intron excision ratio chr2_93410626_93456552 0.45 0.16 0.0e+00 0.29 0.26 0.28 0.28 2.0e-32 3.6e-29 1.6e-30 5.8e-31
13 BLA gene expression LOC120093158 0.14 0.09 2.2e-05 0.08 0.03 0.04 0.01 4.0e-05 8.8e-03 2.8e-03 5.5e-02
14 Adipose gene expression LOC120093158 0.23 0.13 0.0e+00 0.12 0.12 0.12 0.12 1.1e-13 2.4e-13 1.1e-13 1.1e-13
15 Liver intron excision ratio chr2_93458436_93460630 0.49 0.14 0.0e+00 0.34 0.34 0.35 0.35 3.1e-39 1.5e-38 5.1e-40 1.0e-39
16 Eye mRNA stability LOC120093158 0.41 0.19 4.1e-04 0.21 0.18 0.11 0.19 3.3e-04 1.1e-03 1.1e-02 7.4e-04
17 PL gene expression LOC120093158 0.13 0.09 3.3e-09 0.07 0.07 0.06 0.07 5.8e-08 3.7e-08 4.9e-07 4.1e-08
18 Eye intron excision ratio chr2_93456672_93458264 0.74 0.14 4.6e-08 0.38 0.35 0.28 0.37 5.5e-07 2.0e-06 3.1e-05 1.2e-06
19 Liver intron excision ratio chr2_93456672_93458264 0.46 0.15 0.0e+00 0.32 0.32 0.33 0.32 7.5e-37 1.2e-35 3.4e-37 9.9e-37
20 Eye gene expression LOC120093158 0.9 0.07 1.3e-12 0.29 0.41 0.39 0.38 2.0e-05 2.0e-07 4.8e-07 6.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.73.23.7-1.7-1.51.4-1.71.9-1.91.9-1.9-1.9-1.8-1.8-1.8-1.81.9-1.81.91.8-1.7-1.7-1.8
Area under the delay curve0.81.21.61.00.9-1.01.0-1.01.0-1.01.11.11.11.11.21.2-1.01.1-1.3-1.21.31.21.2
BMI with tail0.51.62.81.41.7-1.51.5-1.31.3-1.21.31.31.31.31.41.3-1.41.2-1.1-1.01.01.20.8
BMI without tail0.42.14.51.62.1-1.91.7-1.41.4-1.21.51.41.51.51.41.5-1.41.6-1.2-1.11.01.40.8
Body weight0.41.65.61.52.2-2.41.7-1.01.0-0.91.01.01.11.11.01.1-1.01.4-0.8-0.70.71.10.2
Weight adjusted by age0.10.20.40.20.7-0.6-0.10.4-0.40.2-0.5-0.5-0.5-0.5-0.6-0.50.4-0.3-0.10.10.1-0.5-0.3
Bone surface4.28.29.8-2.4-1.81.8-2.73.1-3.13.1-3.1-3.1-3.0-3.0-3.0-3.03.1-2.83.03.0-2.9-2.8-3.1
Bone volume3.97.79.5-2.3-1.61.6-2.53.0-3.03.0-3.0-3.0-2.9-2.9-3.0-3.03.1-2.72.82.9-2.7-2.8-3.0
Breakpoint value in progressive ratio session0.10.31.30.61.2-0.90.6-0.20.2-0.00.40.40.40.40.30.4-0.10.5-0.6-0.40.50.50.2
Number of licking bursts0.20.60.7-0.8-0.60.8-0.70.8-0.80.8-0.7-0.8-0.7-0.7-0.7-0.70.8-0.70.70.8-0.7-0.7-0.7
Context. condit. distance diff. score0.30.40.60.3-0.2-0.10.5-0.70.7-0.60.70.70.70.70.70.7-0.80.7-0.2-0.60.40.70.7
Locomotion velocity, session 11.61.82.91.71.6-1.71.7-1.31.3-1.21.31.31.31.31.21.2-1.31.4-1.2-1.21.21.30.9
Locomotion distance, session 10.30.31.60.81.1-1.31.0-0.40.4-0.30.40.40.40.40.40.4-0.30.7-0.2-0.30.30.5-0.1
Locomotion velocity, session 21.51.83.11.61.8-1.71.6-1.31.3-1.21.31.21.31.31.21.2-1.11.4-1.3-1.11.31.20.9
Locomotion distance, session 20.20.32.30.81.5-1.50.9-0.20.2-0.10.20.20.30.30.20.2-0.00.5-0.30.00.20.3-0.4
Locomotion velocity, session 30.00.00.10.1-0.1-0.10.2-0.20.2-0.20.20.20.20.20.10.1-0.20.1-0.2-0.20.20.10.2
Locomotion distance, session 30.60.70.8-0.8-0.60.5-0.70.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.90.9-0.80.70.9-0.8-0.8-0.9
Stereotopy head waving bouts, day 30.30.30.7-0.00.2-0.3-0.20.7-0.70.6-0.7-0.7-0.7-0.7-0.6-0.60.7-0.40.50.6-0.5-0.5-0.8
Stereotopy head waving duration, day 30.20.20.60.80.7-0.70.6-0.40.4-0.40.30.30.30.30.40.4-0.30.5-0.4-0.40.50.40.2
Locomotion velocity, session 78.39.112.1-2.8-2.22.1-2.73.2-3.23.4-3.0-3.1-2.9-3.0-3.1-3.13.3-2.73.53.3-3.4-2.8-3.3
Locomotion distance, session 74.86.27.9-2.8-2.52.5-2.52.5-2.52.6-2.3-2.4-2.3-2.3-2.5-2.52.5-2.32.82.5-2.7-2.3-2.3
Stereotopy head waving bouts, day 70.30.30.90.80.9-1.00.8-0.50.5-0.50.40.40.40.50.50.5-0.40.5-0.6-0.40.50.40.2
Stereotopy head waving duration, day 70.81.01.51.21.1-1.21.2-1.01.0-1.00.90.90.90.91.01.0-1.01.0-1.1-0.91.00.90.8
Locomotion velocity, session 83.54.25.42.22.0-2.32.3-2.12.1-2.02.12.12.12.12.02.0-2.12.1-1.9-2.02.02.01.6
Locomotion distance, session 80.81.22.01.21.0-1.41.4-1.01.1-0.91.11.11.21.21.11.1-1.01.3-0.5-0.90.81.20.6
Degree of sensitization distance0.20.30.6-0.6-0.60.6-0.60.5-0.50.6-0.4-0.4-0.4-0.4-0.4-0.40.5-0.40.80.5-0.7-0.4-0.5
Degree of sensitization stereotypy1.21.32.11.41.5-1.41.4-1.11.1-1.11.01.01.01.11.11.1-1.11.1-1.3-1.01.11.00.8
Conditioned locomotion0.10.10.20.30.5-0.40.4-0.20.2-0.30.20.20.20.20.30.2-0.20.2-0.3-0.30.30.30.2
Cocaine response after cond. corrected0.30.41.1-0.8-1.10.9-0.90.6-0.50.6-0.5-0.5-0.5-0.5-0.5-0.50.5-0.60.80.6-0.7-0.5-0.4
Cocaine response after cond. not corrected0.60.91.9-1.2-1.41.2-1.30.9-0.90.9-0.8-0.8-0.8-0.8-0.9-0.90.9-1.01.00.9-1.0-1.0-0.6
Cocaine response before conditioning0.50.60.8-0.7-0.40.5-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.9-0.90.8-0.80.60.8-0.7-0.9-0.8
Saline control response1.41.92.6-1.1-0.60.5-1.11.5-1.51.5-1.5-1.5-1.5-1.5-1.4-1.51.5-1.31.41.5-1.3-1.3-1.6
Bone: connectivity density1.82.93.9-1.7-1.71.7-1.71.7-1.71.8-1.6-1.7-1.6-1.6-1.7-1.71.7-1.62.01.7-1.9-1.6-1.6
Bone: cortical apparent density1.11.72.31.31.1-1.01.5-1.41.4-1.31.41.41.41.41.31.3-1.41.3-1.4-1.41.31.31.2
Bone: cortical area0.30.51.0-0.10.6-0.6-0.40.8-0.80.7-0.9-0.9-0.9-0.9-0.9-0.90.9-0.60.30.8-0.3-0.7-1.0
Bone: cortical porosity0.40.50.7-0.5-0.10.1-0.60.7-0.80.7-0.8-0.8-0.8-0.8-0.7-0.80.7-0.70.50.7-0.5-0.7-0.7
Bone: cortical porosity0.20.20.3-0.20.3-0.2-0.30.5-0.50.4-0.6-0.6-0.5-0.5-0.5-0.50.5-0.40.20.5-0.2-0.4-0.6
Bone: cortical thickness0.10.21.20.51.1-1.10.30.2-0.30.2-0.3-0.3-0.3-0.3-0.3-0.30.4-0.1-0.10.30.2-0.2-0.6
Bone: cortical thickness2.22.66.72.12.6-2.41.8-1.41.4-1.51.21.21.21.21.31.3-1.21.4-2.0-1.52.01.41.1
Bone: cortical tissue density1.21.92.41.31.1-1.01.5-1.41.4-1.41.41.41.41.41.41.4-1.41.3-1.4-1.41.31.31.3
Condit. Reinf. active minus inactive responses1.01.16.71.62.6-2.51.5-0.50.5-0.40.40.30.50.50.50.5-0.30.9-0.8-0.30.70.7-0.4
Condit. Reinf. active-inactive response ratio1.41.58.61.92.9-2.81.8-0.70.7-0.60.60.50.70.70.70.7-0.41.1-1.0-0.40.80.9-0.3
Condit. Reinf. active responses0.60.75.41.32.3-2.31.1-0.00.0-0.0-0.1-0.10.00.00.10.10.10.5-0.40.10.40.3-0.8
Condit. Reinf. inactive responses0.00.10.10.10.2-0.3-0.10.3-0.30.2-0.3-0.4-0.3-0.3-0.3-0.30.3-0.20.10.2-0.1-0.2-0.3
Incentive salience index mean0.91.27.21.72.7-2.71.6-0.40.4-0.40.40.30.40.50.50.5-0.30.9-0.8-0.20.70.7-0.5
Condit. Reinf. lever presses0.60.93.51.51.8-1.91.4-0.60.6-0.60.60.60.60.60.60.6-0.60.9-0.7-0.50.60.80.0
Condit. Reinf. active minus inactive responses4.36.68.4-2.0-1.31.3-2.32.8-2.82.8-2.8-2.8-2.7-2.7-2.8-2.82.9-2.42.62.8-2.6-2.6-2.9
Condit. Reinf. active-inactive response ratio2.23.54.9-1.3-0.70.8-1.62.0-2.02.1-2.0-2.1-2.0-2.0-2.0-2.02.2-1.71.92.1-1.9-1.9-2.2
Condit. Reinf. active responses6.39.111.2-2.4-1.71.6-2.83.2-3.23.2-3.2-3.3-3.2-3.2-3.3-3.33.3-2.93.13.3-3.1-3.0-3.3
Condit. Reinf. inactive responses0.40.60.8-0.5-0.50.3-0.70.9-0.90.8-0.9-0.9-0.9-0.9-0.9-0.90.8-0.70.90.8-0.8-0.8-0.9
Condit. Reinf. lever presses2.73.94.9-1.7-1.01.1-1.72.2-2.12.2-2.1-2.1-2.1-2.1-2.0-2.02.2-1.82.02.2-2.1-1.8-2.2
Condit. Reinf. lever reinforcers received6.79.411.4-2.5-1.71.7-2.83.3-3.33.3-3.3-3.3-3.3-3.3-3.3-3.33.4-2.93.13.3-3.1-3.1-3.3
Conditioned reinforcement - actives2.18.313.0-3.6-2.82.9-2.53.0-3.03.3-2.7-2.7-2.7-2.7-2.7-2.62.7-2.53.33.0-3.3-2.5-2.8
Conditioned reinforcement - inactives0.30.91.2-0.6-0.50.8-0.81.1-1.11.1-1.1-1.1-1.0-1.1-1.1-1.01.0-0.90.80.9-0.8-1.0-0.9
Conditioned locomotion2.84.16.4-2.5-2.02.2-1.72.1-2.12.2-1.9-1.9-1.9-1.9-1.7-1.71.7-1.82.52.2-2.4-1.8-2.1
Patch foraging indifference point 0 sec0.20.41.5-0.9-1.21.2-0.90.5-0.50.4-0.6-0.5-0.6-0.6-0.7-0.60.5-0.70.40.3-0.3-0.7-0.0
Patch foraging indifference point AUC0.20.40.60.60.6-0.60.6-0.70.7-0.70.60.60.60.60.60.6-0.60.6-0.8-0.70.70.60.7
Delay disc. indifference point, 0s delay0.10.10.2-0.0-0.40.40.0-0.30.3-0.50.20.20.20.20.20.2-0.30.00.2-0.1-0.20.00.2
Delay disc. indifference point, 16s delay0.70.91.41.10.9-0.90.9-0.80.8-0.80.90.90.90.91.11.1-0.71.0-1.2-1.11.11.21.0
Delay disc. indifference point, 2s delay0.10.10.90.40.9-0.90.50.1-0.10.1-0.1-0.1-0.0-0.00.10.10.30.30.20.2-0.00.1-0.5
Delay disc. indifference point, 24s delay0.10.20.50.30.4-0.40.3-0.40.4-0.30.40.40.40.40.30.4-0.30.4-0.7-0.50.60.50.6
Delay disc. indifference point, 4s delay1.92.12.81.31.3-1.41.4-1.31.3-1.21.41.41.41.41.61.5-1.51.5-1.5-1.61.71.51.5
Delay disc. indifference point, 8s delay0.20.30.80.40.1-0.10.2-0.50.5-0.50.50.50.40.40.50.5-0.60.4-0.8-0.80.90.40.9
Indifference point function ln k0.00.10.30.1-0.2-0.00.3-0.40.4-0.30.50.50.50.50.50.5-0.40.4-0.1-0.30.10.50.3
Indifference point function log k0.00.10.30.1-0.2-0.00.3-0.40.4-0.30.50.50.50.50.50.5-0.40.4-0.1-0.30.10.50.3
Patch foraging total patch changes 0 sec0.00.10.9-0.4-0.90.8-0.60.1-0.1-0.0-0.2-0.2-0.2-0.2-0.3-0.20.1-0.3-0.0-0.10.2-0.20.3
Patch foraging total patch changes 12 sec0.00.10.3-0.2-0.40.5-0.4-0.0-0.0-0.2-0.1-0.1-0.2-0.1-0.0-0.1-0.1-0.3-0.2-0.30.2-0.20.4
Patch foraging total patch changes 18 sec0.30.71.50.80.9-1.00.8-0.90.8-1.00.70.70.70.70.70.7-0.70.8-1.2-1.01.20.80.9
Patch foraging total patch changes 24 sec0.10.30.6-0.0-0.20.10.3-0.60.6-0.60.60.70.60.60.70.6-0.70.5-0.3-0.60.40.50.8
Patch foraging total patch changes 6 sec0.20.30.80.60.1-0.10.3-0.60.5-0.70.40.50.40.40.40.4-0.50.3-0.7-0.70.90.30.8
Patch foraging time to switch 0 sec0.10.32.20.71.5-1.40.70.0-0.00.20.1-0.00.20.10.10.10.30.40.20.20.00.3-0.7
Patch foraging water rate 0 sec0.10.41.10.5-0.30.20.2-0.70.6-0.90.50.50.40.50.60.6-0.60.4-1.0-0.90.80.51.1
Patch foraging water rate 12 sec0.31.22.6-1.2-1.61.4-1.51.0-1.00.9-1.1-1.1-1.1-1.1-0.9-1.01.1-1.20.80.9-0.9-0.9-0.5
Patch foraging water rate 18 sec0.20.30.6-0.4-0.70.7-0.70.6-0.60.5-0.7-0.6-0.7-0.7-0.4-0.50.5-0.70.50.5-0.6-0.5-0.4
Patch foraging water rate 24 sec0.50.71.30.4-0.20.10.5-1.01.0-0.91.01.01.01.00.91.0-0.90.8-0.8-0.90.80.81.2
Patch foraging water rate 6 sec1.21.83.7-1.5-1.91.8-1.61.2-1.31.2-1.3-1.3-1.3-1.3-1.3-1.31.3-1.41.11.1-1.2-1.3-0.8
Seeking ratio, delayed vs. immediate footshock4.66.610.9-3.0-3.23.3-3.12.4-2.52.3-2.5-2.5-2.6-2.6-2.4-2.52.2-2.82.22.1-2.3-2.4-1.7
Distance traveled before self-admin0.30.71.10.70.5-0.71.1-0.70.8-0.51.01.01.01.00.90.9-1.00.9-0.5-0.80.70.90.7
Distance traveled after self-admin0.00.00.10.1-0.30.3-0.1-0.10.1-0.20.00.00.00.0-0.1-0.10.0-0.10.1-0.1-0.1-0.10.1
Extensor digitorum longus weight7.329.047.26.36.7-6.96.5-5.15.2-4.85.25.15.45.45.45.2-4.85.8-4.6-4.74.75.43.4
Bone: elastic displacement0.50.61.4-0.40.2-0.2-0.40.8-0.80.9-0.8-0.8-0.8-0.8-0.7-0.80.9-0.60.81.0-0.9-0.7-1.2
Bone: elastic work0.91.22.2-0.70.1-0.0-0.71.2-1.21.2-1.2-1.3-1.2-1.2-1.2-1.21.2-0.91.01.3-1.1-1.0-1.5
Bone: endosteal estimation1.43.55.0-1.4-0.70.8-1.62.0-2.02.1-2.0-2.0-1.9-1.9-1.9-2.02.1-1.72.02.1-2.0-1.8-2.2
Bone: endosteal perimeter0.61.51.7-1.1-0.90.9-1.31.3-1.31.3-1.3-1.3-1.3-1.2-1.2-1.21.3-1.21.31.3-1.2-1.1-1.2
Epididymis fat weight0.41.93.40.90.8-1.21.4-1.31.4-1.21.51.51.51.51.71.8-1.51.5-1.0-1.20.91.71.2
Delta time in closed arm before/after self-admin0.30.31.00.1-0.30.30.3-0.70.7-0.80.60.70.50.50.60.7-1.00.3-0.2-0.30.20.30.5
Delta time in open arm before/after self-admin0.30.40.8-0.5-0.40.3-0.70.8-0.80.9-0.7-0.7-0.7-0.7-0.7-0.70.9-0.60.50.5-0.5-0.6-0.5
Diff in mean of infusions in LGA sessions0.20.32.40.51.5-1.40.8-0.00.10.10.10.10.20.20.20.20.40.6-0.3-0.00.30.5-0.3
Delay discount exponential model param0.71.01.4-0.9-0.80.8-0.90.9-0.90.8-0.9-0.9-0.9-0.9-1.1-1.10.9-1.01.21.1-1.2-1.0-1.1
Extinction: sum of active levers before priming0.10.10.20.10.5-0.5-0.10.3-0.40.2-0.5-0.5-0.5-0.5-0.5-0.40.3-0.3-0.10.2-0.0-0.4-0.3
Active lever presses in extinction session 60.10.10.2-0.4-0.20.3-0.1-0.30.3-0.20.40.40.40.40.10.1-0.10.1-0.3-0.20.20.10.4
Bone: final force0.30.51.0-0.10.8-0.6-0.30.7-0.70.7-0.8-0.8-0.8-0.8-0.8-0.80.9-0.50.40.8-0.4-0.6-1.0
Bone: final moment0.50.81.6-0.40.3-0.2-0.71.0-1.01.0-1.0-1.1-1.0-1.0-1.1-1.11.1-0.80.81.1-0.7-0.9-1.2
Food consumed during 24 hour testing period0.51.02.81.51.7-1.61.2-0.90.8-0.90.80.80.80.80.80.8-0.70.9-1.0-0.81.00.80.5
Glucose0.60.92.21.41.5-1.51.0-0.80.8-0.90.70.70.70.70.70.6-0.70.8-1.1-0.81.20.70.6
Heart weight0.71.21.41.20.8-0.71.0-1.21.2-1.21.11.21.11.11.01.1-1.20.9-1.1-1.11.01.01.1
Delay discount hyperbolic model param0.91.11.6-1.1-1.11.1-1.10.9-0.90.9-1.0-1.0-1.0-1.0-1.1-1.10.9-1.11.21.2-1.3-1.1-1.0
Intermittent access intake day 1-15 change0.63.16.0-2.4-2.12.2-2.01.7-1.71.6-1.6-1.6-1.7-1.7-1.7-1.61.5-1.81.61.6-1.6-1.7-1.2
Intermittent access intake escalation0.52.96.7-2.6-2.42.4-2.01.6-1.61.6-1.5-1.4-1.5-1.5-1.6-1.51.4-1.71.51.4-1.6-1.6-1.0
Intermittent access intake escalation 23.15.38.1-2.8-2.72.9-2.62.2-2.22.0-2.2-2.2-2.2-2.3-2.4-2.22.0-2.42.02.1-2.1-2.4-1.6
Intermitt. access day 1 inactive lever presses0.44.96.52.11.5-1.32.1-2.52.5-2.62.52.52.52.42.22.3-2.32.2-2.1-2.12.02.12.1
Intermitt. access day 15 inactive lever presses0.52.54.01.30.5-0.51.0-1.81.8-1.91.71.71.61.61.51.6-1.71.4-1.9-1.81.91.52.0
Intermitt. access escalation Index0.82.53.71.70.7-0.81.2-1.81.7-1.91.51.61.51.61.71.5-1.51.4-1.6-1.81.81.71.8
Intermittent access day 1 total infusions1.85.56.7-2.3-1.81.7-2.42.5-2.62.5-2.6-2.6-2.6-2.6-2.5-2.62.4-2.42.12.2-1.9-2.4-2.1
Intermittent access day 15 total infusions3.89.414.3-3.8-3.43.3-3.43.2-3.13.2-3.0-3.0-3.0-3.0-3.0-3.02.9-3.12.92.8-2.7-2.9-2.3
Intermittent access terminal intake (last 3 days)5.910.313.5-3.6-3.23.2-3.73.3-3.33.2-3.3-3.3-3.4-3.4-3.3-3.33.1-3.42.72.9-2.6-3.2-2.4
Intermittent access total infusions6.07.110.1-3.2-2.62.6-2.92.8-2.82.8-2.7-2.7-2.7-2.7-2.7-2.72.5-2.72.42.5-2.3-2.6-2.1
Intermittent access day 1 locomotion0.91.72.2-1.0-1.00.9-1.51.4-1.41.3-1.5-1.5-1.5-1.5-1.4-1.41.4-1.31.11.1-0.7-1.3-1.0
Intermittent access day 15 total locomotion0.62.33.0-1.3-0.91.2-1.61.5-1.51.3-1.7-1.7-1.7-1.7-1.6-1.61.6-1.71.31.5-1.2-1.6-1.4
Intermittent access total locomotion2.63.14.4-1.7-1.41.6-2.11.7-1.81.5-2.0-1.9-2.0-2.0-2.0-1.91.8-2.01.41.6-1.2-1.9-1.4
Intermittent access standard deviation0.63.47.8-2.8-2.82.7-2.21.7-1.71.8-1.5-1.5-1.6-1.6-1.5-1.51.2-1.91.61.5-1.7-1.6-1.0
Left kidney weight0.00.20.50.5-0.30.2-0.1-0.50.5-0.60.40.40.40.40.20.4-0.50.2-0.6-0.50.40.20.7
Right kidney weight0.10.51.31.10.6-0.70.4-0.70.7-0.90.50.60.50.50.50.6-0.60.5-0.9-0.90.90.50.8
Cocaine induced anxiety0.30.71.20.90.7-0.70.8-0.80.8-0.70.90.90.90.90.70.9-0.90.8-1.1-1.01.10.70.9
Post-drug Anxiety1.61.82.91.21.4-1.41.7-1.21.3-1.01.51.41.51.51.41.5-1.31.5-1.0-1.11.01.40.9
Baseline Anxiety0.00.10.2-0.20.5-0.50.4-0.10.1-0.10.00.00.10.10.20.00.00.20.30.2-0.40.2-0.4
Tail length0.20.83.31.11.4-1.81.2-0.70.7-0.60.80.70.80.80.70.9-0.61.1-0.5-0.60.60.80.3
Length with tail0.10.32.50.71.1-1.60.9-0.20.2-0.10.20.20.30.30.20.4-0.10.6-0.1-0.10.10.3-0.3
Length without tail0.10.61.1-0.5-0.40.2-0.50.8-0.80.8-0.8-0.8-0.8-0.8-0.9-0.80.9-0.70.90.9-1.0-0.8-1.1
Times rat made contact with spout0.10.10.1-0.1-0.20.2-0.40.3-0.30.2-0.3-0.3-0.3-0.3-0.3-0.30.3-0.40.10.2-0.1-0.3-0.1
Lifetime Intake3.74.67.5-2.7-2.42.4-2.52.2-2.22.2-2.1-2.1-2.2-2.2-2.1-2.11.9-2.31.81.9-1.7-2.1-1.5
Liver weight, left0.10.11.00.41.0-0.90.4-0.00.0-0.0-0.0-0.00.00.00.10.10.10.2-0.3-0.00.10.2-0.2
Liver weight, right0.61.01.80.80.4-0.50.8-1.11.1-1.21.01.01.00.90.91.0-1.20.9-1.4-1.31.20.91.3
Locomotor activity0.00.00.0-0.1-0.0-0.00.10.1-0.10.1-0.0-0.0-0.1-0.1-0.0-0.1-0.0-0.1-0.0-0.0-0.1-0.1-0.0
Locomotor testing distance0.00.00.0-0.10.0-0.20.10.2-0.20.2-0.1-0.1-0.1-0.1-0.2-0.20.2-0.00.20.1-0.1-0.2-0.2
Locomotor testing rearing0.31.01.5-1.1-1.10.9-1.20.9-1.00.8-1.0-1.0-1.0-1.0-1.1-1.20.9-1.10.70.8-0.7-1.2-0.6
Locomotion in novel chamber0.10.11.20.21.1-0.90.6-0.00.0-0.00.00.00.10.10.10.2-0.20.3-0.4-0.00.20.2-0.2
Locomotion in novel chamber post-restriction0.10.20.60.5-0.0-0.10.3-0.60.5-0.70.50.50.40.40.40.5-0.80.3-0.4-0.50.50.30.6
Fecal boli incidents, locomotor time 10.00.10.40.60.4-0.60.3-0.30.3-0.20.30.30.40.30.10.1-0.10.4-0.2-0.30.40.20.2
Change in fecal boli incidents, locomotor task2.22.35.6-2.4-1.81.8-1.61.6-1.61.6-1.4-1.4-1.5-1.5-1.3-1.51.1-1.51.31.3-1.5-1.4-1.1
Time >=10cm from walls, locomotor time 11.82.33.0-1.7-1.11.2-1.71.6-1.61.5-1.6-1.6-1.6-1.6-1.5-1.41.3-1.61.41.5-1.5-1.6-1.4
Bouts of movement, locomotor time 11.51.93.70.5-0.40.30.6-1.51.5-1.61.51.61.41.51.61.6-1.91.0-1.4-1.61.31.21.9
Total resting periods, locomotor time 10.91.02.30.1-0.50.40.4-1.11.1-1.11.11.21.11.11.21.2-1.50.6-0.9-1.10.90.81.5
Rest time, locomotor task time 10.20.31.0-0.0-0.40.40.3-0.70.7-0.70.60.70.60.60.60.6-1.00.3-0.3-0.50.30.30.7
Distance moved, locomotor task time 10.00.00.10.10.3-0.30.10.1-0.10.1-0.1-0.1-0.0-0.00.10.10.40.1-0.10.0-0.10.2-0.1
Vertical activity count, locomotor time 10.10.51.1-0.30.2-0.1-0.30.9-0.91.0-0.8-0.8-0.7-0.7-0.6-0.61.1-0.50.80.9-0.8-0.4-1.1
Time >=10cm from walls, locomotor time 20.71.92.5-1.4-0.50.6-1.31.4-1.41.3-1.5-1.5-1.5-1.5-1.6-1.41.4-1.31.21.5-1.4-1.5-1.5
Bouts of movement, locomotor time 20.82.74.61.00.5-0.51.2-1.71.7-1.61.81.91.71.71.81.8-2.21.4-1.9-1.91.71.52.1
Total resting periods, locomotor time 20.72.95.01.00.5-0.51.2-1.71.7-1.61.81.91.81.81.91.9-2.21.4-2.0-2.01.81.62.2
Rest time, locomotor task time 20.40.71.20.30.3-0.30.7-0.80.8-0.70.91.00.90.90.90.9-1.10.7-0.9-1.01.10.81.1
Distance moved, locomotor task time 20.00.00.10.20.1-0.10.1-0.30.2-0.40.10.10.10.10.20.2-0.00.1-0.3-0.1-0.00.20.2
Vertical activity count, locomotor time 20.20.41.81.11.3-1.20.9-0.50.5-0.50.40.30.40.40.30.3-0.20.5-0.5-0.20.20.4-0.1
Light reinforcement 10.62.94.11.81.4-1.41.4-1.81.8-1.91.61.71.61.61.81.6-1.81.5-2.0-1.82.01.71.8
Light reinforcement 21.53.44.32.12.1-1.91.9-1.81.8-1.81.71.71.71.72.01.8-1.71.9-2.0-1.82.02.01.6
Bone: marrow area1.33.14.7-1.3-0.60.6-1.51.9-1.92.0-1.9-1.9-1.8-1.8-1.8-1.92.0-1.61.92.0-1.9-1.6-2.2
Bone: maximum diameter0.10.20.4-0.4-0.00.0-0.60.5-0.50.4-0.6-0.6-0.6-0.6-0.6-0.60.5-0.60.20.5-0.1-0.6-0.4
Bone: maximum force0.40.81.7-0.30.6-0.5-0.51.0-1.01.0-1.1-1.1-1.0-1.0-1.0-1.01.1-0.80.61.1-0.6-0.9-1.3
Bone: maximum moment0.71.42.3-0.70.1-0.1-0.91.3-1.31.3-1.3-1.4-1.3-1.3-1.3-1.31.4-1.11.01.4-1.0-1.2-1.5
Mean time between licks in bursts0.00.20.70.40.9-0.80.40.3-0.30.4-0.2-0.3-0.1-0.1-0.1-0.10.40.10.30.4-0.30.0-0.8
Mean num. licks in bursts0.10.30.40.70.4-0.60.4-0.60.6-0.60.50.50.50.50.50.5-0.60.4-0.6-0.60.60.40.6
Cd content in liver1.31.42.81.11.0-0.60.9-1.31.3-1.41.21.21.21.21.21.2-1.30.9-1.7-1.31.51.01.4
Co content in liver1.51.82.60.70.2-0.11.0-1.51.5-1.51.61.61.61.61.41.4-1.51.2-1.1-1.41.21.31.6
Cu content in liver1.31.54.4-1.6-2.12.0-1.61.0-1.00.9-0.9-0.9-0.9-1.0-1.2-1.20.9-1.31.10.9-1.1-1.3-0.5
Fe content in liver1.01.31.6-1.1-0.80.8-1.01.2-1.21.2-1.1-1.1-1.1-1.1-1.2-1.21.1-1.11.31.2-1.2-1.2-1.2
K content in liver0.10.10.9-0.6-1.00.8-0.30.0-0.00.10.10.10.10.1-0.1-0.10.0-0.10.50.1-0.4-0.10.1
Mg content in liver0.20.20.9-0.7-0.90.8-0.40.3-0.30.4-0.2-0.2-0.2-0.2-0.3-0.30.3-0.30.80.4-0.6-0.3-0.2
Mn content in liver0.20.20.30.4-0.1-0.20.5-0.40.5-0.30.50.50.60.50.40.4-0.40.50.0-0.40.10.40.4
Na content in liver0.40.51.0-0.8-0.91.0-1.00.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.70.6-0.70.50.5-0.8-0.7-0.3
Rb content in liver0.10.20.3-0.1-0.10.20.3-0.50.5-0.30.60.60.60.50.30.3-0.40.3-0.2-0.30.40.30.4
Se content in liver0.20.20.40.3-0.30.00.3-0.60.6-0.50.60.60.60.60.50.5-0.50.5-0.1-0.50.20.40.6
Sr content in liver0.10.10.50.10.0-0.20.20.2-0.20.3-0.1-0.1-0.1-0.1-0.1-0.10.20.20.70.2-0.70.0-0.5
Zn content in liver1.01.23.7-1.4-1.91.9-1.40.8-0.80.8-0.8-0.8-0.8-0.8-0.9-0.90.8-1.11.00.7-1.0-1.0-0.3
Bone: minimum diameter1.22.35.6-0.30.8-0.8-0.71.7-1.71.7-1.7-1.7-1.6-1.6-1.7-1.71.9-1.11.61.9-1.4-1.3-2.4
Time in familiar zone, hab. session 10.20.30.7-0.1-0.80.80.1-0.50.5-0.40.60.60.60.60.50.5-0.60.3-0.1-0.50.20.30.7
Time in novel zone, hab. session 10.10.10.3-0.10.3-0.3-0.40.4-0.40.2-0.5-0.5-0.5-0.5-0.4-0.40.5-0.3-0.10.30.0-0.3-0.3
Total zone transitions, hab. session 10.30.51.50.91.2-1.21.1-0.50.5-0.40.50.50.50.50.60.6-0.50.7-0.5-0.40.40.70.1
Total locomotion distance, hab. session 10.20.20.70.10.6-0.60.20.5-0.50.5-0.5-0.5-0.5-0.5-0.4-0.40.6-0.20.40.5-0.4-0.2-0.8
Locomotion velocity, hab. session 10.10.21.00.41.0-1.00.50.3-0.30.3-0.3-0.3-0.3-0.2-0.1-0.10.30.00.10.3-0.20.0-0.7
Time in familiar zone, hab. session 20.30.42.1-0.5-1.41.4-0.3-0.50.5-0.40.50.60.50.50.40.4-0.6-0.0-0.2-0.50.20.10.9
Time in novel zone, hab. session 20.50.51.0-0.00.8-0.8-0.30.8-0.80.7-0.9-0.9-0.8-0.8-0.7-0.70.9-0.40.40.8-0.4-0.5-1.0
Total zone transitions, hab. session 20.70.91.30.90.5-0.71.1-1.01.0-1.01.01.11.01.01.01.0-1.11.0-0.8-1.00.91.00.9
Total locomotion distance, hab. session 20.00.00.30.30.4-0.50.3-0.00.1-0.00.00.00.10.10.00.0-0.10.1-0.1-0.00.10.1-0.1
Locomotion velocity, hab. session 20.00.00.20.30.3-0.40.3-0.00.0-0.00.00.00.00.00.00.0-0.10.1-0.1-0.00.10.1-0.1
Novel to familiar place preference ratio0.10.10.3-0.10.1-0.2-0.30.4-0.40.4-0.4-0.5-0.4-0.4-0.3-0.30.5-0.20.50.5-0.4-0.2-0.5
Novelty place preference0.10.10.2-0.2-0.0-0.1-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.3-0.30.5-0.20.40.4-0.3-0.3-0.4
Time in novel zone, NPP test0.00.00.0-0.00.1-0.2-0.20.1-0.10.1-0.1-0.1-0.1-0.1-0.0-0.00.2-0.00.10.1-0.0-0.0-0.1
Total zone transitions, NPP test1.01.52.31.41.0-1.11.5-1.21.2-1.11.31.31.21.31.31.3-1.31.3-1.0-1.21.01.31.0
Total locomotion distance, NPP test0.10.10.60.50.6-0.80.50.0-0.00.0-0.0-0.0-0.0-0.00.10.1-0.00.2-0.0-0.00.10.2-0.3
Locomotion velocity, NPP test0.10.10.40.10.3-0.50.10.4-0.40.4-0.4-0.4-0.4-0.4-0.3-0.30.4-0.20.30.4-0.2-0.2-0.6
Intraocular pressure0.50.83.51.21.9-1.61.4-0.60.6-0.60.60.60.70.70.80.7-0.80.9-0.6-0.60.60.80.1
Delta distance traveled before/after self-admin3.23.54.6-1.7-1.71.8-2.11.7-1.81.4-2.0-2.0-2.0-2.0-2.0-2.02.1-1.91.71.8-1.9-1.9-1.6
Delta ambulatory time before/after self-admin2.13.64.8-1.7-1.81.9-2.21.8-1.81.5-2.1-2.1-2.1-2.1-2.1-2.02.1-2.01.71.8-1.9-2.0-1.6
Parametrial fat weight0.00.00.1-0.20.4-0.30.30.1-0.10.2-0.0-0.00.0-0.0-0.1-0.1-0.00.10.10.2-0.2-0.0-0.3
Pavlov. Cond. lever latency0.10.10.7-0.6-0.70.8-0.50.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.30.10.1-0.2-0.20.2
Pavlov. Cond. magazine entry latency0.00.10.30.40.5-0.60.30.1-0.00.1-0.1-0.1-0.0-0.00.00.00.00.10.00.10.00.1-0.3
Pavlov. Cond. change in total contacts0.80.82.91.41.6-1.71.4-0.70.7-0.60.70.60.70.70.70.7-0.61.0-0.7-0.60.80.80.2
Pavlov. Cond. index score0.30.41.10.90.9-1.00.9-0.50.5-0.50.50.50.50.50.50.5-0.50.6-0.5-0.50.60.60.2
Pavlov. Cond. latency score0.30.41.00.80.8-1.00.9-0.50.5-0.50.50.50.50.50.60.6-0.50.7-0.5-0.50.60.60.3
Pavlov. Cond. lever contacts0.10.10.70.40.7-0.90.40.2-0.20.2-0.2-0.2-0.2-0.2-0.1-0.10.20.10.20.2-0.10.0-0.5
Pavlov. Cond. magazine entry number0.50.61.2-1.0-1.01.1-1.00.7-0.70.7-0.6-0.6-0.7-0.7-0.7-0.70.7-0.80.70.6-0.8-0.7-0.4
Pavlov. Cond. intertrial magazine entries0.70.91.1-0.9-0.90.8-1.01.0-1.00.9-1.0-1.0-1.0-1.0-0.9-0.90.9-1.00.90.9-0.9-0.9-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.80.8-1.00.8-0.40.4-0.40.40.40.40.40.40.4-0.40.6-0.4-0.40.50.50.2
Pavlov. Cond. response bias0.10.21.00.70.9-1.00.7-0.10.1-0.10.10.00.10.10.10.1-0.10.3-0.1-0.10.20.3-0.3
Pavlov. Cond. lever latency1.21.72.01.41.2-1.41.4-1.31.3-1.31.31.31.31.31.31.3-1.31.3-1.3-1.21.21.21.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.20.2-0.0-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.1-0.20.2-0.20.10.3-0.1-0.2-0.2
Pavlov. Cond. change in total contacts0.81.93.3-0.8-0.10.2-0.91.5-1.51.6-1.5-1.6-1.5-1.5-1.5-1.51.7-1.21.41.6-1.4-1.3-1.8
Pavlov. Cond. index score0.71.11.6-0.8-0.20.4-0.81.2-1.21.2-1.1-1.2-1.1-1.1-1.1-1.11.2-1.01.11.2-1.0-1.0-1.3
Pavlov. Cond. latency score0.71.21.5-1.0-0.50.6-1.01.2-1.21.2-1.2-1.2-1.1-1.1-1.1-1.11.2-1.01.11.2-1.1-1.0-1.2
Pavlov. Cond. lever contacts0.91.31.5-1.2-0.91.1-1.11.2-1.21.2-1.2-1.2-1.2-1.2-1.1-1.11.2-1.11.21.1-1.1-1.0-1.1
Pavlov. Cond. magazine entry number0.10.10.20.1-0.20.10.1-0.30.3-0.40.30.30.30.30.30.3-0.40.2-0.2-0.40.20.20.4
Pavlov. Cond. intertrial magazine entries0.00.00.20.30.4-0.50.40.0-0.00.10.0-0.00.10.0-0.00.00.10.20.20.1-0.20.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.71.11.5-0.8-0.30.5-0.81.2-1.11.2-1.1-1.1-1.1-1.1-1.1-1.11.2-1.01.01.2-1.0-1.0-1.2
Pavlov. Cond. response bias0.91.31.8-0.9-0.50.6-1.01.2-1.21.3-1.2-1.2-1.2-1.2-1.2-1.21.3-1.11.11.2-1.0-1.0-1.3
Time in closed arm before self-admin0.10.21.2-0.5-1.11.0-0.70.1-0.20.1-0.2-0.2-0.2-0.2-0.5-0.40.6-0.40.40.3-0.3-0.5-0.0
Time in closed arm after self-admin0.60.71.50.1-0.60.60.4-1.11.1-1.21.01.11.01.00.91.0-1.00.6-0.5-0.70.50.61.0
Time in open arm before self-admin0.40.50.9-0.50.1-0.1-0.50.9-0.90.9-0.9-0.9-0.9-0.9-0.5-0.70.7-0.60.60.8-0.7-0.4-0.9
Time in open arm after self-admin0.10.10.70.20.8-0.80.20.4-0.30.6-0.1-0.2-0.1-0.10.1-0.10.20.2-0.3-0.10.10.3-0.1
Bone: periosteal estimation1.12.74.8-0.80.2-0.2-1.11.8-1.81.8-1.9-1.9-1.8-1.8-1.8-1.82.0-1.41.51.9-1.4-1.6-2.2
Bone: periosteal perimeter0.51.01.3-0.7-0.30.3-1.01.1-1.11.0-1.1-1.2-1.1-1.1-1.1-1.11.2-1.00.81.1-0.8-1.0-1.1
Bone: post-yield work2.44.15.9-2.2-2.22.2-2.42.0-2.01.9-2.1-2.0-2.1-2.1-2.1-2.11.9-2.21.91.8-1.8-2.1-1.5
Progressive ratio test 1 active lever presses0.81.32.3-1.5-1.51.5-1.51.1-1.11.0-1.1-1.1-1.1-1.1-1.2-1.11.0-1.30.90.9-0.8-1.2-0.6
Progressive ratio test 1 breakpoint0.91.52.4-1.5-1.51.5-1.61.2-1.21.0-1.2-1.2-1.3-1.3-1.3-1.21.1-1.41.01.0-0.8-1.3-0.7
Progressive ratio test 1 inactive lever presses0.00.00.1-0.4-0.00.1-0.10.1-0.10.3-0.0-0.00.0-0.0-0.2-0.1-0.0-0.00.20.2-0.2-0.1-0.2
Progressive ratio test 2 active lever presses5.17.211.2-3.3-2.52.6-2.62.8-2.82.9-2.6-2.6-2.6-2.6-2.6-2.62.4-2.72.72.6-2.6-2.6-2.4
Progressive ratio test 2 breakpoint5.46.910.7-3.3-2.42.6-2.52.7-2.72.8-2.6-2.6-2.6-2.6-2.6-2.62.4-2.62.62.6-2.6-2.6-2.3
Progressive ratio test 2 inactive lever presses0.51.52.3-1.5-1.21.3-1.31.3-1.31.3-1.2-1.2-1.2-1.2-1.3-1.21.3-1.21.01.1-1.0-1.2-0.9
Incentive Sensitization - Responses2.46.78.1-2.8-1.71.9-2.22.7-2.72.8-2.7-2.7-2.7-2.6-2.5-2.72.6-2.52.72.7-2.8-2.5-2.8
Incentive Sensitization - Breakpoint2.96.58.2-2.9-1.82.0-2.22.7-2.72.7-2.6-2.6-2.6-2.6-2.5-2.62.5-2.52.62.7-2.7-2.4-2.7
Sum of active levers in priming session hrs 5-61.71.62.2-1.0-0.71.0-1.01.3-1.31.4-1.3-1.3-1.3-1.3-1.4-1.31.5-1.21.21.4-1.3-1.2-1.4
Progressive ratio0.10.20.7-0.4-0.70.9-0.6-0.30.2-0.50.10.1-0.10.00.40.2-0.6-0.4-0.6-0.50.30.10.9
Food seeking constrained by brief footshock0.81.04.01.32.0-2.01.6-0.60.6-0.40.70.60.70.70.81.0-0.51.1-0.5-0.40.60.9-0.1
Seeking ratio, punishment vs. effort0.30.73.21.11.7-1.81.5-0.30.40.00.60.50.70.70.40.60.01.10.10.00.10.6-0.6
Retroperitoneal fat weight0.10.61.10.30.8-1.01.1-0.70.8-0.60.90.90.90.90.81.0-0.91.0-0.5-0.50.40.80.4
Reaction time number correct0.51.72.6-1.1-0.90.7-1.11.4-1.41.4-1.3-1.3-1.3-1.3-1.3-1.31.4-1.21.51.6-1.4-1.3-1.6
Reaction time mean minus median0.74.77.12.52.2-1.82.1-2.32.2-2.42.12.12.12.11.91.9-2.21.8-2.7-2.22.61.82.1
Reaction time mean minus median AUC0.74.57.02.62.5-2.12.1-2.12.1-2.32.02.02.01.91.91.8-2.01.8-2.6-2.12.61.71.8
Reaction time num false alarms2.54.35.3-1.6-1.21.3-1.92.3-2.32.2-2.3-2.3-2.3-2.3-2.2-2.12.3-2.02.02.2-2.1-2.1-2.2
Reaction time num false alarms AUC1.94.35.3-1.7-1.31.3-2.02.3-2.32.2-2.3-2.3-2.3-2.3-2.2-2.12.3-2.01.92.1-2.0-2.1-2.1
Reaction time trials correct on left0.51.72.6-1.1-0.90.7-1.11.4-1.41.4-1.3-1.3-1.3-1.3-1.3-1.31.4-1.21.51.6-1.4-1.3-1.6
Reaction time trials on left0.51.52.5-1.0-0.80.6-1.01.3-1.31.4-1.2-1.3-1.2-1.2-1.2-1.21.3-1.11.51.5-1.4-1.2-1.6
Reaction time mean0.81.73.61.51.9-1.51.5-1.21.2-1.21.11.11.11.11.21.1-1.21.2-1.6-1.21.71.20.9
Reaction time mean AUC0.61.64.01.62.0-1.61.4-1.11.1-1.11.01.01.01.01.11.0-1.01.1-1.5-1.11.71.10.8
Median of all reaction times0.40.62.41.01.6-1.21.0-0.60.6-0.50.50.50.60.60.70.6-0.50.7-0.8-0.51.00.80.3
Reaction time omissions3.15.18.42.82.9-2.82.3-2.12.1-2.31.91.91.92.02.22.0-2.12.2-2.5-2.22.62.11.8
Reaction time false alarm rate0.40.50.8-0.6-0.50.6-0.80.8-0.80.7-0.9-0.8-0.9-0.9-0.8-0.70.8-0.70.50.6-0.7-0.7-0.5
Reaction time premature initiation rate0.30.52.3-0.9-1.41.5-1.00.4-0.40.3-0.5-0.4-0.6-0.5-0.4-0.50.2-0.80.20.2-0.5-0.50.1
Reaction time premature initiations0.41.22.7-1.2-1.61.6-1.41.0-1.00.9-1.0-1.0-1.0-1.0-0.9-1.00.8-1.30.90.9-1.1-1.1-0.6
Std. dev. reaction times0.82.84.91.81.8-1.41.6-1.71.7-1.81.61.61.51.51.51.4-1.71.4-2.2-1.82.21.41.6
Reaction time trials completed0.51.52.5-1.0-0.80.6-1.01.3-1.31.4-1.2-1.3-1.2-1.2-1.2-1.21.3-1.11.51.5-1.4-1.2-1.6
Reaction time trials AUC0.41.42.4-0.9-0.70.5-0.91.3-1.21.3-1.2-1.2-1.1-1.1-1.2-1.21.3-1.11.41.5-1.3-1.2-1.5
Run reversals in cocaine runway, females0.20.20.50.30.7-0.70.7-0.40.4-0.40.40.40.40.40.50.4-0.30.6-0.4-0.50.60.50.4
Run reversals in cocaine runway, males0.70.82.71.41.7-1.71.2-0.60.6-0.60.60.60.60.60.70.5-0.40.9-0.9-0.70.90.70.3
Latency to leave start box in cocaine runway0.50.71.1-1.0-1.00.9-0.90.8-0.80.8-0.9-0.9-0.9-0.9-1.1-0.80.7-0.90.70.7-0.8-1.0-0.5
Latency to leave start box in cocaine runway, F2.42.94.0-2.0-2.01.9-1.91.7-1.71.6-1.7-1.7-1.8-1.8-1.8-1.61.4-1.81.51.4-1.6-1.9-1.2
Latency to leave start box in cocaine runway, M2.01.92.81.71.6-1.61.6-1.41.4-1.41.31.31.31.31.21.3-1.31.4-1.4-1.21.41.31.0
Std. dev. time between licks in bursts0.10.20.5-0.3-0.10.1-0.20.5-0.50.6-0.5-0.5-0.4-0.4-0.4-0.40.5-0.30.60.6-0.6-0.3-0.7
Total sessions with >9 infusions0.70.92.6-1.4-1.51.6-1.30.9-0.90.9-0.8-0.8-0.8-0.8-0.9-0.90.7-1.00.70.7-0.5-0.8-0.3
Short access day 1 total inactive lever presses0.10.21.7-0.6-1.11.3-0.4-0.20.2-0.30.20.20.10.10.10.2-0.4-0.2-0.2-0.20.20.00.6
Short access day 10 total inactive lever presses0.31.92.91.00.3-0.21.2-1.61.6-1.51.71.71.71.71.61.7-1.71.3-1.0-1.30.81.41.3
Short access day 1 total infusions0.40.83.3-1.5-1.71.8-1.10.6-0.60.6-0.6-0.5-0.7-0.6-0.6-0.60.4-0.90.60.5-0.6-0.7-0.1
Short access day 10 total infusions1.72.84.4-2.1-1.91.8-2.01.8-1.81.9-1.7-1.7-1.7-1.7-1.7-1.71.5-1.71.41.4-1.3-1.6-1.0
Short access total infusions1.11.52.7-1.6-1.61.6-1.61.2-1.21.2-1.2-1.2-1.2-1.2-1.2-1.21.0-1.30.91.0-0.8-1.2-0.6
Short access day 1 locomotion0.00.00.3-0.2-0.40.5-0.40.0-0.0-0.00.00.0-0.0-0.0-0.1-0.1-0.0-0.2-0.1-0.10.30.00.3
Short access day 10 total locomotion0.10.41.00.50.6-0.60.5-0.60.6-0.40.70.70.70.70.50.7-0.70.7-0.8-0.81.00.60.8
Short access total locomotion0.20.40.8-0.6-0.60.6-0.90.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.60.5-0.70.40.5-0.2-0.6-0.3
One hour access (0.3 mA shock)6.57.710.0-3.2-2.82.7-2.72.8-2.82.7-2.8-2.8-2.8-2.8-2.8-2.82.6-2.72.82.8-2.9-2.8-2.5
Compulsive drug intake1.01.42.11.30.7-0.71.4-1.31.3-1.21.41.41.41.41.31.3-1.21.4-0.7-1.00.51.30.9
One hour access (shock baseline)5.013.115.8-4.0-3.33.2-3.83.7-3.73.6-3.8-3.8-3.8-3.8-3.9-3.73.6-3.73.43.5-3.3-3.7-3.2
Social response proportion0.40.50.80.90.5-0.60.5-0.80.8-0.90.80.80.80.80.70.7-0.70.6-0.7-0.80.80.60.8
Social responses1.21.62.31.10.9-1.01.0-1.41.4-1.41.41.41.41.31.21.2-1.31.1-1.2-1.31.51.01.3
Social time0.10.20.4-0.00.1-0.2-0.50.4-0.40.2-0.5-0.5-0.5-0.5-0.6-0.60.5-0.50.10.3-0.0-0.6-0.3
Soleus weight0.51.53.41.51.8-1.91.4-1.21.2-1.11.21.11.21.21.11.1-0.91.2-1.2-1.01.31.10.7
Bone: stiffness0.10.20.40.30.6-0.6-0.10.3-0.30.3-0.4-0.4-0.4-0.4-0.5-0.50.5-0.3-0.00.30.1-0.4-0.5
Tibialis anterior weight4.415.133.34.95.7-5.84.8-3.53.5-3.23.53.43.73.73.73.6-3.14.2-3.2-3.13.33.82.0
Time to tail flick, vehicle, before self-admin0.50.61.3-0.9-0.80.8-0.50.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.60.8-0.71.11.1-1.1-0.7-1.0
Time to tail flick, vehicle, after self-admin1.22.45.5-2.3-2.12.1-1.61.5-1.51.7-1.2-1.2-1.2-1.2-1.1-1.21.3-1.31.81.5-1.7-1.2-1.2
Time to tail flick, test, before self-admin0.40.40.70.5-0.1-0.20.4-0.80.8-0.70.80.80.80.80.70.7-0.70.5-0.6-0.70.60.60.9
Time to tail flick, test, after self-admin0.70.71.7-1.0-1.01.0-1.30.8-0.80.8-0.8-0.8-0.9-0.9-0.8-0.80.6-0.90.50.6-0.5-0.9-0.3
Delta time to tail flick, vehicle, before/after SA1.81.93.3-1.8-1.71.8-1.61.5-1.51.6-1.3-1.3-1.3-1.3-1.2-1.31.1-1.31.31.2-1.2-1.3-0.9
Delta time to tail flick, test, before/after SA0.00.00.1-0.30.20.1-0.10.1-0.10.2-0.0-0.0-0.0-0.0-0.00.0-0.10.1-0.2-0.10.3-0.00.2
Tibia length0.51.44.4-1.7-2.11.8-1.50.9-0.91.0-0.8-0.8-0.8-0.8-1.0-0.80.8-1.01.31.1-1.2-1.0-0.6
Ambulatory time before self-admin0.41.11.91.00.9-1.11.4-0.91.0-0.71.21.21.21.21.21.0-1.21.1-0.8-1.11.01.10.8
Ambulatory time after self-admin0.40.71.1-0.5-0.70.6-0.80.8-0.80.7-0.9-0.9-0.9-0.9-1.0-1.01.0-0.90.70.8-0.8-0.9-0.8
Bone: tissue strength1.81.93.5-1.6-1.81.7-1.91.3-1.31.1-1.4-1.3-1.4-1.4-1.4-1.41.1-1.51.21.1-1.2-1.5-0.7
Total heroin consumption0.81.02.0-0.7-0.30.1-0.81.2-1.21.4-1.0-1.0-0.9-1.0-1.2-1.01.2-0.80.91.1-1.1-0.9-1.2
Bone: trabecular number0.61.11.3-1.1-0.91.0-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.11.1-1.11.01.0-0.9-1.1-0.9
Bone: trabecular spacing1.72.53.01.51.2-1.21.6-1.71.7-1.71.71.71.71.71.61.6-1.71.6-1.6-1.61.51.51.5
Bone: trabecular thickness3.34.65.5-2.0-1.31.5-2.02.3-2.32.3-2.3-2.3-2.3-2.3-2.3-2.32.3-2.21.92.2-1.9-2.2-2.2
Bone: trabecular tissue density2.44.26.22.22.3-2.22.1-2.12.0-2.21.91.91.91.91.91.9-2.01.9-2.5-2.12.41.81.9
Water consumed over 24 hours0.00.10.20.40.5-0.30.3-0.20.2-0.20.10.10.10.10.10.1-0.10.2-0.4-0.20.40.20.2
Number of responses in last shaping day0.30.50.8-0.8-0.80.9-0.90.6-0.60.5-0.7-0.7-0.8-0.8-0.8-0.70.6-0.80.40.5-0.3-0.7-0.3