Hub : Genes

LOC108352165

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability LOC108352165 0.17 0.11 2.5e-04 0.07 0.08 0.08 0.07 1.5e-04 4.0e-05 5.2e-05 1.1e-04
2 NAcc gene expression LOC108352165 0.13 0.08 1.0e-11 0.07 0.04 0.08 0.01 2.4e-11 7.6e-07 1.4e-11 3.6e-03
3 PL mRNA stability LOC108352165 0.05 0.03 1.7e-05 0.06 0.04 0.05 0.01 7.9e-07 3.4e-05 3.5e-06 1.0e-02
4 Liver gene expression LOC108352165 0.02 0.02 6.8e-03 0.01 0.01 0 0 3.4e-02 6.8e-02 8.1e-02 1.4e-01
5 pVTA gene expression LOC108352165 0.24 0.1 1.1e-16 0.22 0.13 0.21 0.03 1.9e-17 2.7e-10 1.5e-16 3.3e-03
6 Adipose gene expression LOC108352165 0.1 0.06 3.6e-09 0.09 0.07 0.06 0.08 1.1e-09 6.4e-08 2.2e-07 4.2e-09
7 BLA gene expression LOC108352165 0.13 0.08 2.9e-05 0.1 0.05 0.08 -0 3.9e-06 1.7e-03 6.4e-05 8.6e-01
8 LHb gene expression LOC108352165 0.22 0.12 1.9e-03 0.06 -0.01 0.02 -0.01 1.2e-02 5.8e-01 1.3e-01 8.9e-01
9 Brain mRNA stability LOC108352165 0.05 0.04 5.0e-04 0.04 0.04 0.03 0.04 5.5e-05 1.8e-04 5.4e-04 1.9e-04
10 OFC gene expression LOC108352165 0.23 0.18 7.0e-03 0.03 0.04 0.01 0 6.3e-02 3.5e-02 1.6e-01 2.6e-01
11 PL gene expression LOC108352165 0.13 0.06 1.8e-15 0.14 0.13 0.15 0.02 4.8e-15 9.1e-14 3.7e-16 2.3e-03
12 Adipose mRNA stability LOC108352165 0.02 0.02 4.4e-03 0.03 0.02 0.03 0.02 4.6e-04 9.9e-04 6.3e-04 9.3e-04
13 Brain gene expression LOC108352165 0.1 0.06 1.9e-08 0.09 0.09 0.1 0.1 6.3e-09 7.9e-09 2.4e-09 2.7e-09
14 RMTg mRNA stability LOC108352165 0.29 0.13 1.2e-05 0.17 0.2 0.23 0.18 3.2e-05 6.7e-06 7.3e-07 1.7e-05
15 IC gene expression LOC108352165 0.09 0.06 9.8e-03 0.04 0.04 0.05 0.04 9.6e-03 8.4e-03 3.6e-03 6.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.10.10.6-0.8-0.4-0.1-0.0-0.1-0.1-0.2-0.2-0.2-0.4-0.2-0.40.20.3-0.1
Area under the delay curve1.51.86.22.51.61.31.61.11.61.01.01.01.50.91.60.40.51.0
BMI with tail0.62.13.6-1.3-1.6-1.7-1.3-1.6-1.3-1.4-1.4-1.5-1.8-1.4-1.2-1.2-1.2-1.9
BMI without tail3.410.312.7-3.5-3.6-3.4-3.2-3.4-3.2-3.1-3.1-3.2-3.4-3.0-2.9-2.7-2.8-3.4
Body weight3.716.018.4-3.5-4.1-4.3-4.0-4.3-4.0-4.2-4.2-4.2-3.6-4.0-3.4-4.1-4.3-3.8
Weight adjusted by age3.45.26.6-2.4-2.2-2.3-2.3-2.3-2.4-2.2-2.2-2.4-2.1-2.2-2.6-2.3-2.3-2.0
Bone surface0.00.10.2-0.2-0.2-0.2-0.2-0.2-0.3-0.3-0.3-0.20.1-0.1-0.5-0.2-0.40.2
Bone volume0.10.20.5-0.7-0.6-0.3-0.3-0.3-0.3-0.4-0.4-0.3-0.4-0.4-0.6-0.1-0.2-0.1
Breakpoint value in progressive ratio session0.70.81.2-1.1-0.9-1.0-0.9-0.9-0.9-0.8-0.8-0.9-1.1-0.9-0.8-0.7-0.6-1.0
Number of licking bursts0.10.20.3-0.3-0.4-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.0-0.5-0.5-0.5
Context. condit. distance diff. score0.60.81.8-0.4-0.7-0.7-0.7-0.7-0.7-0.9-0.9-0.7-1.3-1.2-0.9-0.6-0.7-1.3
Locomotion velocity, session 14.64.97.62.82.62.12.12.12.12.22.22.12.72.51.81.61.42.5
Locomotion distance, session 12.02.53.61.41.71.61.51.61.51.71.71.71.21.61.21.71.91.1
Locomotion velocity, session 26.27.38.32.42.72.72.82.72.72.72.72.72.72.92.72.52.72.7
Locomotion distance, session 20.30.41.7-0.30.30.60.50.60.40.70.70.70.10.70.21.11.30.2
Locomotion velocity, session 31.92.13.21.81.81.41.51.41.41.31.31.51.71.60.81.11.11.6
Locomotion distance, session 34.24.56.12.22.52.22.22.22.22.12.12.22.02.11.82.02.11.9
Stereotopy head waving bouts, day 30.30.30.70.80.60.50.60.50.60.50.50.50.70.60.60.40.20.7
Stereotopy head waving duration, day 30.20.20.60.80.50.40.50.40.50.40.40.50.40.60.30.50.10.5
Locomotion velocity, session 71.11.22.01.41.31.11.01.11.01.21.21.10.91.10.80.90.90.9
Locomotion distance, session 72.83.55.41.61.82.02.02.02.02.02.02.00.81.61.92.32.20.9
Stereotopy head waving bouts, day 70.60.71.3-0.1-0.7-0.8-0.7-0.8-0.7-1.0-1.0-0.9-0.7-0.9-0.6-0.9-1.2-0.9
Stereotopy head waving duration, day 70.81.02.0-0.2-0.8-1.0-0.9-1.0-1.0-1.1-1.1-1.0-0.6-1.0-1.0-1.2-1.4-0.7
Locomotion velocity, session 80.20.31.61.30.80.40.50.40.50.40.40.40.00.30.50.30.1-0.2
Locomotion distance, session 80.40.62.6-1.0-0.8-0.4-0.6-0.4-0.5-0.5-0.5-0.4-1.6-0.8-0.80.10.2-1.4
Degree of sensitization distance1.01.02.5-1.5-1.4-0.9-0.9-0.9-0.8-0.8-0.8-0.9-1.6-1.0-0.8-0.4-0.4-1.3
Degree of sensitization stereotypy0.90.91.3-0.5-0.9-0.9-0.9-0.9-0.9-1.1-1.1-1.0-1.0-1.1-0.7-0.9-1.1-1.1
Conditioned locomotion4.95.67.1-2.6-2.7-2.3-2.2-2.3-2.3-2.4-2.4-2.4-2.6-2.6-2.3-2.0-1.9-2.6
Cocaine response after cond. corrected0.10.10.30.50.40.40.30.40.30.40.40.40.30.40.20.40.20.4
Cocaine response after cond. not corrected0.91.01.61.31.21.10.91.10.91.01.01.11.01.00.80.90.71.1
Cocaine response before conditioning0.91.11.91.31.41.01.01.01.11.01.01.11.11.11.00.80.81.0
Saline control response2.53.33.8-1.7-1.8-1.9-1.8-1.9-1.9-1.9-1.9-1.9-1.6-1.8-1.9-1.9-1.9-1.6
Bone: connectivity density0.10.10.40.10.40.30.40.30.40.40.40.40.10.30.10.50.70.3
Bone: cortical apparent density3.04.15.61.52.02.12.12.12.02.22.22.11.72.11.92.22.41.7
Bone: cortical area6.39.612.5-2.6-2.9-3.2-3.2-3.2-3.1-3.3-3.3-3.2-2.2-3.1-3.4-3.5-3.4-2.5
Bone: cortical porosity0.30.30.9-0.4-0.5-0.6-0.5-0.6-0.5-0.6-0.6-0.60.1-0.4-0.5-0.8-0.90.2
Bone: cortical porosity0.80.81.9-0.5-0.9-1.0-0.9-1.0-0.9-1.0-1.0-1.0-0.3-0.7-0.8-1.2-1.4-0.3
Bone: cortical thickness5.49.011.6-2.9-2.9-3.1-3.0-3.1-3.0-3.2-3.2-3.1-2.1-3.1-3.4-3.3-2.9-2.4
Bone: cortical thickness1.72.03.4-1.1-1.1-1.4-1.3-1.4-1.4-1.5-1.5-1.4-1.0-1.5-1.9-1.7-1.3-1.2
Bone: cortical tissue density3.44.66.21.62.12.22.22.22.22.32.32.21.82.22.12.32.51.9
Condit. Reinf. active minus inactive responses2.93.23.9-2.0-1.9-1.8-1.9-1.8-1.8-1.8-1.8-1.8-1.7-1.9-1.9-1.7-1.4-1.7
Condit. Reinf. active-inactive response ratio1.51.52.1-1.4-1.3-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.4-1.4-1.1-1.1-0.9-1.4
Condit. Reinf. active responses4.75.87.7-2.8-2.6-2.4-2.6-2.4-2.5-2.5-2.5-2.4-2.3-2.5-2.3-2.2-1.9-2.2
Condit. Reinf. inactive responses1.01.22.1-1.4-1.2-1.1-1.2-1.1-1.2-1.1-1.1-1.1-1.0-1.0-0.9-0.9-0.8-0.9
Incentive salience index mean2.42.93.6-1.9-1.7-1.7-1.9-1.7-1.8-1.7-1.7-1.7-1.5-1.8-1.8-1.6-1.4-1.6
Condit. Reinf. lever presses0.20.20.4-0.7-0.5-0.4-0.6-0.4-0.6-0.3-0.3-0.4-0.6-0.4-0.5-0.2-0.1-0.6
Condit. Reinf. active minus inactive responses0.81.02.0-0.4-0.7-1.0-0.9-1.0-1.0-0.9-0.9-1.0-0.8-1.1-1.4-1.3-1.2-1.1
Condit. Reinf. active-inactive response ratio2.22.63.6-1.4-1.6-1.7-1.6-1.7-1.7-1.5-1.5-1.7-1.2-1.4-1.9-1.9-1.8-1.3
Condit. Reinf. active responses0.20.30.8-0.3-0.4-0.4-0.4-0.4-0.5-0.3-0.3-0.4-0.8-0.7-0.6-0.4-0.3-0.9
Condit. Reinf. inactive responses0.50.71.40.60.80.90.90.90.90.70.71.00.20.60.91.21.20.2
Condit. Reinf. lever presses0.50.72.4-1.1-1.0-0.7-0.6-0.7-0.7-0.6-0.6-0.7-1.5-1.0-0.4-0.2-0.2-1.4
Condit. Reinf. lever reinforcers received0.20.31.3-0.4-0.5-0.4-0.4-0.4-0.5-0.4-0.4-0.4-1.0-0.8-0.6-0.3-0.2-1.1
Conditioned reinforcement - actives0.10.10.5-0.7-0.20.0-0.20.0-0.20.20.20.1-0.30.2-0.20.50.50.0
Conditioned reinforcement - inactives0.81.21.6-1.2-1.3-1.2-1.1-1.1-1.1-1.1-1.1-1.2-1.1-1.1-1.1-1.1-1.0-1.1
Conditioned locomotion0.81.02.6-1.6-1.4-1.1-1.1-1.0-1.1-0.7-0.7-0.8-1.2-0.8-1.1-0.4-0.3-0.9
Patch foraging indifference point 0 sec0.61.13.5-1.9-1.4-1.1-0.7-1.1-0.7-0.9-0.9-0.9-1.4-1.0-0.8-0.3-0.1-1.3
Patch foraging indifference point AUC0.10.10.3-0.3-0.3-0.4-0.1-0.5-0.2-0.5-0.5-0.4-0.5-0.50.1-0.3-0.3-0.5
Delay disc. indifference point, 0s delay0.20.20.70.60.2-0.2-0.5-0.1-0.5-0.4-0.4-0.3-0.1-0.5-0.5-0.7-0.9-0.0
Delay disc. indifference point, 16s delay0.80.91.81.30.81.11.30.91.30.70.70.70.60.51.30.60.80.3
Delay disc. indifference point, 2s delay0.30.31.71.30.70.40.60.20.6-0.0-0.00.10.70.00.6-0.3-0.30.3
Delay disc. indifference point, 24s delay5.56.27.62.72.32.72.82.72.82.32.32.32.62.42.82.02.12.5
Delay disc. indifference point, 4s delay0.30.32.41.60.70.20.60.10.6-0.2-0.2-0.00.5-0.20.6-0.5-0.60.2
Delay disc. indifference point, 8s delay1.61.96.92.61.91.21.31.01.31.11.11.21.81.11.30.40.21.3
Indifference point function ln k0.71.32.30.60.91.11.01.31.11.31.31.30.71.10.71.51.40.9
Indifference point function log k0.71.32.30.60.91.11.01.31.11.31.31.30.71.10.71.51.40.9
Patch foraging total patch changes 0 sec0.71.44.1-2.0-1.5-1.2-0.7-1.2-0.7-1.0-1.0-1.0-1.6-1.2-0.8-0.3-0.1-1.5
Patch foraging total patch changes 12 sec0.60.82.6-1.6-1.3-0.9-0.3-1.1-0.3-1.0-1.0-0.9-1.0-0.9-0.2-0.4-0.1-1.0
Patch foraging total patch changes 18 sec0.30.41.5-0.8-0.7-0.60.0-0.7-0.0-0.7-0.7-0.5-1.1-0.8-0.10.00.1-1.2
Patch foraging total patch changes 24 sec1.73.03.7-1.8-1.7-1.8-1.6-1.9-1.7-1.8-1.8-1.7-1.8-1.9-1.6-1.5-1.5-1.8
Patch foraging total patch changes 6 sec1.01.64.8-2.2-1.7-1.3-1.0-1.4-1.0-1.4-1.4-1.2-1.1-1.1-0.7-0.7-0.6-1.0
Patch foraging time to switch 0 sec0.91.82.81.71.51.41.41.41.41.21.21.11.51.21.50.80.91.4
Patch foraging water rate 0 sec3.87.910.8-3.2-3.1-2.9-2.8-3.0-2.8-2.7-2.7-2.7-3.3-2.8-2.6-2.1-2.2-3.2
Patch foraging water rate 12 sec0.51.02.9-1.4-1.3-0.8-0.9-0.7-0.9-0.5-0.5-0.5-1.7-0.8-1.4-0.1-0.2-1.5
Patch foraging water rate 18 sec2.03.16.0-2.3-2.2-1.6-1.8-1.6-1.8-1.5-1.5-1.5-2.5-1.6-1.9-0.8-1.1-1.9
Patch foraging water rate 24 sec5.57.714.6-3.4-3.4-2.5-2.5-2.6-2.5-2.6-2.6-2.5-3.8-2.8-2.8-1.5-1.7-3.4
Patch foraging water rate 6 sec0.30.51.1-0.8-0.4-0.7-0.8-0.7-0.9-0.4-0.4-0.5-1.1-0.5-0.9-0.2-0.3-0.8
Seeking ratio, delayed vs. immediate footshock0.70.81.5-0.8-0.4-1.1-1.2-0.9-1.2-0.7-0.7-1.0-0.6-0.7-1.2-1.0-1.1-0.7
Distance traveled before self-admin1.21.62.2-0.9-0.8-1.2-1.4-1.2-1.4-1.4-1.4-1.3-1.1-1.2-1.3-1.4-1.5-1.2
Distance traveled after self-admin1.51.83.4-1.8-1.6-1.1-1.4-1.1-1.4-1.2-1.2-1.3-1.8-1.3-1.4-0.8-0.7-1.5
Extensor digitorum longus weight0.10.51.9-1.2-0.9-0.4-0.4-0.4-0.3-0.3-0.3-0.4-1.4-0.70.20.10.3-1.3
Bone: elastic displacement2.22.54.7-2.2-1.8-1.6-1.6-1.6-1.5-1.6-1.6-1.5-1.5-1.5-1.8-1.3-1.0-1.5
Bone: elastic work7.29.411.5-3.4-3.2-3.3-3.1-3.3-3.0-3.3-3.3-3.2-2.3-2.9-3.1-3.2-2.8-2.4
Bone: endosteal estimation0.00.00.20.40.20.20.10.20.20.10.10.2-0.2-0.00.40.2-0.0-0.1
Bone: endosteal perimeter0.51.02.6-0.2-0.7-1.0-1.1-1.0-1.0-1.2-1.2-1.0-0.3-0.8-0.8-1.4-1.6-0.5
Epididymis fat weight1.55.37.0-2.2-2.5-2.2-2.5-2.2-2.5-2.2-2.2-2.3-2.7-2.2-2.1-2.1-2.1-2.4
Delta time in closed arm before/after self-admin0.00.00.10.0-0.2-0.10.0-0.10.0-0.2-0.2-0.2-0.1-0.10.1-0.4-0.2-0.1
Delta time in open arm before/after self-admin0.50.50.9-0.9-0.6-0.9-0.4-0.9-0.4-0.7-0.7-0.7-0.7-0.6-0.5-0.4-0.3-0.9
Diff in mean of infusions in LGA sessions0.30.40.8-0.5-0.7-0.9-0.3-0.8-0.3-0.6-0.6-0.8-0.5-0.5-0.3-0.8-0.7-0.8
Delay discount exponential model param2.32.67.9-2.8-1.9-1.5-2.0-1.4-2.0-1.2-1.2-1.3-1.8-1.1-2.0-0.6-0.7-1.3
Extinction: sum of active levers before priming0.30.30.70.30.30.40.60.50.60.70.70.50.30.70.70.60.80.5
Active lever presses in extinction session 60.00.00.1-0.10.1-0.10.1-0.20.1-0.2-0.2-0.3-0.0-0.20.2-0.3-0.1-0.2
Bone: final force6.310.011.8-2.7-3.0-3.4-3.1-3.4-3.1-3.3-3.3-3.3-2.6-3.1-3.3-3.4-3.3-2.8
Bone: final moment7.311.813.3-3.1-3.4-3.6-3.4-3.6-3.4-3.6-3.6-3.6-2.9-3.4-3.5-3.6-3.5-3.0
Food consumed during 24 hour testing period1.21.62.3-1.0-1.3-1.2-1.2-1.2-1.3-1.2-1.2-1.2-1.5-1.4-1.5-1.1-1.1-1.5
Glucose8.012.516.93.63.83.53.43.53.53.53.53.64.13.83.03.13.04.0
Heart weight0.71.11.9-1.0-1.2-1.1-1.3-1.1-1.3-0.7-0.7-1.0-0.8-0.8-1.4-1.2-1.0-0.8
Delay discount hyperbolic model param1.92.27.2-2.7-1.8-1.4-1.8-1.2-1.8-1.0-1.0-1.1-1.7-1.0-1.8-0.5-0.5-1.2
Intermittent access intake day 1-15 change0.00.00.1-0.0-0.2-0.2-0.1-0.2-0.1-0.1-0.1-0.2-0.0-0.1-0.2-0.4-0.3-0.1
Intermittent access intake escalation0.00.00.1-0.0-0.1-0.2-0.1-0.2-0.10.00.0-0.1-0.0-0.0-0.1-0.3-0.2-0.1
Intermittent access intake escalation 20.10.20.4-0.3-0.4-0.6-0.4-0.5-0.4-0.2-0.2-0.3-0.2-0.2-0.4-0.6-0.6-0.2
Intermitt. access day 1 inactive lever presses1.66.29.1-2.7-3.0-2.4-2.3-2.4-2.3-2.5-2.5-2.6-2.8-2.5-2.2-2.2-2.1-2.6
Intermitt. access day 15 inactive lever presses1.12.33.2-1.6-1.5-1.6-1.6-1.5-1.6-1.4-1.4-1.4-1.8-1.7-1.6-1.2-1.1-1.7
Intermitt. access escalation Index0.70.91.2-1.1-0.8-0.9-1.1-1.0-1.1-1.0-1.0-1.0-0.9-0.9-1.1-0.9-0.8-1.0
Intermittent access day 1 total infusions0.10.21.0-1.0-0.6-0.4-0.5-0.5-0.5-0.4-0.4-0.2-0.6-0.3-0.50.10.1-0.3
Intermittent access day 15 total infusions0.40.61.6-1.3-1.0-0.9-0.8-0.9-0.8-0.7-0.7-0.7-0.8-0.6-0.8-0.6-0.4-0.7
Intermittent access terminal intake (last 3 days)0.60.71.5-1.2-1.0-1.0-1.0-1.0-1.0-0.7-0.7-0.7-0.8-0.6-1.0-0.7-0.6-0.6
Intermittent access total infusions0.30.41.1-1.0-0.8-0.8-0.7-0.8-0.7-0.5-0.5-0.5-0.7-0.5-0.7-0.3-0.2-0.5
Intermittent access day 1 locomotion0.20.31.0-1.0-1.0-0.6-0.5-0.6-0.5-0.4-0.4-0.4-0.6-0.3-0.5-0.2-0.1-0.5
Intermittent access day 15 total locomotion0.51.01.5-1.2-1.2-1.1-1.0-1.1-1.0-0.9-0.9-0.9-1.0-0.8-1.0-0.9-0.7-0.9
Intermittent access total locomotion0.50.61.3-1.1-1.2-0.9-0.8-0.9-0.8-0.7-0.7-0.7-0.9-0.7-0.7-0.5-0.4-0.8
Intermittent access standard deviation0.20.32.01.40.80.30.40.40.40.50.50.40.80.60.4-0.2-0.20.4
Left kidney weight0.10.31.40.5-0.2-0.4-0.3-0.4-0.3-0.6-0.6-0.60.1-0.2-0.1-1.0-1.20.1
Right kidney weight0.00.20.80.3-0.1-0.4-0.4-0.4-0.3-0.5-0.5-0.50.1-0.2-0.2-0.9-0.80.1
Cocaine induced anxiety1.11.52.8-1.0-1.2-1.3-1.1-1.3-1.1-1.3-1.3-1.4-0.7-1.1-1.1-1.6-1.7-1.0
Post-drug Anxiety0.10.10.40.0-0.5-0.30.2-0.40.2-0.5-0.5-0.5-0.0-0.30.2-0.6-0.5-0.3
Baseline Anxiety1.92.23.21.21.11.61.81.41.81.31.31.41.21.31.81.51.71.3
Tail length4.718.320.5-4.1-4.5-4.4-4.4-4.5-4.4-4.4-4.4-4.5-3.6-4.2-4.0-4.5-4.5-3.6
Length with tail2.510.817.7-2.3-3.0-3.5-3.4-3.6-3.4-3.6-3.6-3.5-2.1-3.2-2.9-4.1-4.2-2.3
Length without tail0.41.33.80.0-0.6-1.2-1.0-1.2-1.1-1.3-1.3-1.2-0.1-1.1-0.7-1.8-1.9-0.4
Times rat made contact with spout1.51.73.4-1.8-1.7-1.3-1.3-1.3-1.4-1.3-1.3-1.3-1.2-1.1-1.6-1.0-1.0-1.0
Lifetime Intake0.10.10.3-0.5-0.4-0.4-0.3-0.4-0.3-0.1-0.1-0.1-0.3-0.1-0.30.10.2-0.2
Liver weight, left0.50.81.41.11.10.90.80.90.80.70.70.81.21.01.00.70.41.2
Liver weight, right4.37.58.6-2.4-2.6-2.8-2.9-2.8-2.8-2.9-2.9-2.9-2.2-2.7-2.8-2.9-2.9-2.3
Locomotor activity0.40.61.10.80.80.80.70.80.70.80.81.00.60.80.61.10.80.8
Locomotor testing distance0.40.61.40.90.80.80.70.80.70.90.91.00.40.80.61.20.80.5
Locomotor testing rearing0.10.20.9-0.5-0.5-0.3-0.3-0.4-0.2-0.4-0.4-0.2-0.9-0.5-0.40.1-0.0-0.9
Locomotion in novel chamber0.20.30.6-0.6-0.8-0.5-0.3-0.4-0.3-0.7-0.7-0.4-0.6-0.6-0.4-0.3-0.3-0.3
Locomotion in novel chamber post-restriction1.01.63.3-1.8-1.8-1.2-1.3-1.0-1.3-1.1-1.1-1.3-1.2-0.9-1.3-1.0-1.1-0.8
Fecal boli incidents, locomotor time 10.40.61.30.10.80.50.20.90.21.11.10.90.51.00.20.91.10.7
Change in fecal boli incidents, locomotor task3.33.24.81.71.81.92.21.52.21.51.51.71.81.62.21.71.71.7
Time >=10cm from walls, locomotor time 10.10.10.40.30.10.0-0.1-0.3-0.10.10.1-0.0-0.4-0.0-0.10.0-0.0-0.6
Bouts of movement, locomotor time 12.32.63.51.31.51.41.61.51.61.91.91.61.41.81.61.51.71.4
Total resting periods, locomotor time 13.03.34.31.41.61.61.81.71.82.12.11.91.72.11.81.82.01.8
Rest time, locomotor task time 10.70.91.70.50.70.60.80.80.81.11.11.01.11.20.81.00.91.3
Distance moved, locomotor task time 10.71.11.8-0.8-1.0-0.9-0.7-1.2-0.7-1.2-1.2-1.2-1.0-1.2-0.7-1.2-1.1-1.3
Vertical activity count, locomotor time 10.51.21.9-1.0-1.1-0.9-1.1-0.9-1.1-1.1-1.1-1.1-1.4-1.2-1.1-1.0-0.9-1.4
Time >=10cm from walls, locomotor time 20.00.10.2-0.3-0.3-0.0-0.1-0.3-0.1-0.5-0.5-0.3-0.1-0.3-0.1-0.2-0.2-0.2
Bouts of movement, locomotor time 21.11.82.21.51.21.41.31.21.31.41.41.41.31.41.31.11.41.1
Total resting periods, locomotor time 20.61.01.31.10.91.11.00.81.01.11.11.00.91.11.00.81.10.8
Rest time, locomotor task time 20.20.20.50.30.00.20.50.30.50.60.60.30.50.70.50.30.30.5
Distance moved, locomotor task time 20.40.50.8-0.4-0.5-0.6-0.5-0.9-0.5-0.9-0.9-0.8-0.4-0.8-0.5-0.9-0.9-0.8
Vertical activity count, locomotor time 20.20.30.6-0.2-0.2-0.5-0.6-0.5-0.6-0.6-0.6-0.5-0.6-0.8-0.6-0.6-0.5-0.8
Light reinforcement 11.74.17.2-2.7-2.4-1.9-2.0-1.8-2.0-1.9-1.9-1.8-2.4-1.9-2.4-1.4-1.1-2.1
Light reinforcement 22.33.65.2-2.0-2.0-1.7-2.1-1.6-2.1-1.9-1.9-1.9-1.8-1.9-2.3-1.9-1.7-1.6
Bone: marrow area0.00.00.20.40.20.20.10.20.20.10.10.2-0.1-0.00.40.2-0.0-0.1
Bone: maximum diameter1.63.06.4-0.6-1.2-1.8-1.9-1.8-1.7-1.9-1.9-1.8-0.8-1.6-1.7-2.4-2.5-1.2
Bone: maximum force5.710.111.5-2.9-3.1-3.4-3.1-3.4-3.1-3.4-3.4-3.3-2.6-3.1-3.3-3.3-3.2-2.8
Bone: maximum moment6.511.412.8-3.2-3.4-3.6-3.3-3.6-3.3-3.6-3.6-3.5-2.8-3.2-3.5-3.5-3.4-3.0
Mean time between licks in bursts0.71.72.31.51.31.31.51.31.51.31.31.31.31.31.01.11.11.1
Mean num. licks in bursts0.20.41.3-1.2-0.9-0.5-0.6-0.5-0.6-0.5-0.5-0.5-0.6-0.5-0.9-0.2-0.1-0.4
Cd content in liver0.20.20.8-0.3-0.00.30.40.30.40.30.30.3-0.60.00.20.80.9-0.5
Co content in liver0.10.10.4-0.6-0.3-0.1-0.3-0.1-0.3-0.2-0.2-0.2-0.2-0.2-0.3-0.10.10.0
Cu content in liver0.60.71.1-0.9-0.9-0.9-1.0-0.9-1.0-0.9-0.9-0.8-0.5-0.7-1.1-0.9-0.9-0.5
Fe content in liver0.00.10.20.30.10.20.20.20.20.10.10.2-0.3-0.00.20.50.3-0.1
K content in liver2.01.92.7-1.6-1.5-1.3-1.5-1.3-1.5-1.3-1.3-1.3-1.5-1.5-1.2-1.2-1.1-1.4
Mg content in liver0.40.41.5-1.2-0.8-0.4-0.7-0.4-0.7-0.3-0.3-0.4-1.1-0.6-0.6-0.10.0-0.8
Mn content in liver0.10.10.30.10.0-0.2-0.3-0.2-0.3-0.4-0.4-0.2-0.1-0.3-0.5-0.4-0.4-0.2
Na content in liver0.00.00.1-0.10.0-0.0-0.2-0.0-0.20.00.0-0.0-0.2-0.1-0.3-0.1-0.1-0.1
Rb content in liver2.73.14.8-1.9-1.9-1.7-1.7-1.7-1.7-1.6-1.6-1.7-2.2-1.9-1.9-1.4-1.2-2.1
Se content in liver0.30.40.9-0.7-0.7-0.5-0.6-0.5-0.6-0.5-0.5-0.5-1.0-0.9-0.7-0.3-0.3-0.9
Sr content in liver0.30.20.60.10.20.40.60.40.60.40.40.40.70.50.70.40.50.8
Zn content in liver1.31.42.3-1.5-1.4-1.2-1.3-1.2-1.3-1.2-1.2-1.2-1.0-1.0-1.0-1.1-1.0-0.8
Bone: minimum diameter4.47.99.6-2.5-2.9-2.9-2.9-2.9-2.8-3.1-3.1-2.9-2.3-2.8-2.7-2.9-3.1-2.3
Time in familiar zone, hab. session 10.10.10.2-0.3-0.20.20.40.20.40.10.10.1-0.20.10.10.40.40.0
Time in novel zone, hab. session 10.10.10.30.60.3-0.1-0.2-0.1-0.2-0.1-0.1-0.10.1-0.1-0.4-0.3-0.50.1
Total zone transitions, hab. session 10.10.20.5-0.00.10.40.40.40.40.40.40.4-0.10.30.40.70.7-0.0
Total locomotion distance, hab. session 10.50.81.8-1.1-1.0-0.7-0.9-0.7-0.9-0.7-0.7-0.7-1.3-0.9-1.1-0.4-0.3-1.1
Locomotion velocity, hab. session 10.60.81.7-1.3-1.1-0.8-1.0-0.8-0.9-0.7-0.7-0.8-1.3-0.9-0.9-0.4-0.3-1.2
Time in familiar zone, hab. session 20.20.20.50.30.20.40.70.40.70.40.40.5-0.00.40.50.70.60.1
Time in novel zone, hab. session 20.10.10.20.40.50.20.00.2-0.00.10.10.20.40.10.1-0.10.00.3
Total zone transitions, hab. session 20.20.20.8-0.9-0.40.20.00.2-0.00.30.30.2-0.80.1-0.10.80.9-0.6
Total locomotion distance, hab. session 21.01.23.8-1.9-1.4-0.9-1.1-0.9-1.1-0.8-0.8-0.8-1.6-0.9-1.3-0.30.0-1.4
Locomotion velocity, hab. session 21.31.74.5-2.1-1.6-1.1-1.4-1.1-1.4-1.0-1.0-1.1-1.8-1.2-1.4-0.5-0.2-1.5
Novel to familiar place preference ratio2.62.86.6-2.6-2.1-1.7-1.5-1.7-1.5-1.6-1.6-1.7-1.7-1.7-1.5-1.2-0.9-1.7
Novelty place preference2.42.55.8-2.4-2.0-1.6-1.4-1.6-1.4-1.6-1.6-1.6-1.6-1.7-1.4-1.2-0.9-1.6
Time in novel zone, NPP test2.12.35.6-2.4-1.9-1.5-1.3-1.5-1.3-1.5-1.5-1.5-1.6-1.6-1.3-1.0-0.7-1.5
Total zone transitions, NPP test0.10.20.7-0.30.00.30.10.30.10.40.40.3-0.50.2-0.20.70.9-0.4
Total locomotion distance, NPP test0.70.93.3-1.8-1.2-0.5-0.8-0.5-0.8-0.5-0.5-0.5-1.6-0.7-1.20.20.4-1.3
Locomotion velocity, NPP test0.71.13.5-1.9-1.3-0.7-1.0-0.7-1.0-0.6-0.6-0.7-1.6-0.8-1.30.00.2-1.3
Intraocular pressure0.71.02.0-1.4-1.4-1.0-0.6-1.0-0.6-1.0-1.0-1.1-1.2-1.1-0.4-0.8-0.5-1.1
Delta distance traveled before/after self-admin0.10.10.4-0.6-0.40.0-0.00.1-0.00.20.20.1-0.6-0.2-0.10.40.6-0.2
Delta ambulatory time before/after self-admin0.40.51.70.10.30.70.70.80.70.90.90.80.10.50.61.11.30.5
Parametrial fat weight0.81.93.8-1.9-1.9-1.2-1.3-1.2-1.3-1.4-1.4-1.3-1.6-1.2-1.3-1.0-1.0-1.3
Pavlov. Cond. lever latency0.91.11.91.21.11.11.21.11.21.11.11.2-0.10.60.81.41.20.1
Pavlov. Cond. magazine entry latency2.22.84.8-1.1-1.5-1.9-1.8-1.9-1.7-1.8-1.8-1.8-0.9-1.5-1.4-2.1-2.2-1.2
Pavlov. Cond. change in total contacts0.20.20.8-0.9-0.6-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.1-0.2-0.2-0.4-0.1-0.1
Pavlov. Cond. index score3.54.56.0-2.0-2.2-2.3-2.2-2.3-2.2-2.2-2.2-2.3-1.2-1.9-1.8-2.5-2.4-1.5
Pavlov. Cond. latency score2.53.24.8-1.6-1.8-2.0-1.9-2.0-1.9-1.9-1.9-2.0-0.8-1.5-1.6-2.2-2.2-1.0
Pavlov. Cond. lever contacts1.01.22.2-1.5-1.3-1.2-1.2-1.2-1.2-1.1-1.1-1.2-0.4-0.7-1.0-1.2-1.0-0.4
Pavlov. Cond. magazine entry number1.82.24.11.11.51.71.61.71.51.61.61.70.61.21.11.92.00.9
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.9-0.4-0.1-0.4-0.1-0.4-0.2-0.2-0.1-0.7-0.5-0.30.20.4-0.4
Pavlov. Cond. lever-magazine prob. diff.3.64.55.7-2.0-2.2-2.3-2.2-2.3-2.2-2.2-2.2-2.3-1.4-1.9-1.8-2.4-2.3-1.6
Pavlov. Cond. response bias1.61.93.0-1.2-1.4-1.6-1.5-1.6-1.5-1.5-1.5-1.5-0.5-1.1-1.0-1.7-1.7-0.7
Pavlov. Cond. lever latency1.72.44.71.91.81.41.41.41.51.41.41.42.21.71.20.91.02.0
Pavlov. Cond. magazine entry latency0.70.92.30.50.60.91.00.91.10.80.81.0-0.10.41.51.41.30.1
Pavlov. Cond. change in total contacts0.10.20.6-0.5-0.20.20.20.20.10.10.10.2-0.8-0.30.40.70.7-0.6
Pavlov. Cond. index score0.20.31.3-0.7-0.6-0.2-0.1-0.2-0.2-0.3-0.3-0.2-1.2-0.60.20.40.3-1.0
Pavlov. Cond. latency score0.20.31.3-0.7-0.5-0.2-0.2-0.2-0.2-0.3-0.3-0.2-1.2-0.70.20.30.2-1.0
Pavlov. Cond. lever contacts1.31.84.1-1.8-1.7-1.2-1.2-1.2-1.2-1.2-1.2-1.2-2.0-1.4-0.9-0.6-0.7-1.9
Pavlov. Cond. magazine entry number0.40.41.2-0.2-0.4-0.7-0.7-0.7-0.7-0.5-0.5-0.70.3-0.2-0.9-1.1-1.10.1
Pavlov. Cond. intertrial magazine entries1.72.63.9-1.3-1.5-1.6-1.6-1.6-1.7-1.6-1.6-1.6-1.4-1.5-2.0-1.7-1.7-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.5-0.30.10.10.10.1-0.0-0.00.1-0.9-0.40.40.60.5-0.7
Pavlov. Cond. response bias0.30.41.8-1.1-0.9-0.4-0.4-0.4-0.4-0.4-0.4-0.4-1.3-0.7-0.20.30.2-1.1
Time in closed arm before self-admin0.70.81.31.00.60.91.10.81.10.80.80.81.10.91.10.70.61.0
Time in closed arm after self-admin1.51.62.91.30.51.31.71.11.71.11.10.91.41.31.70.70.91.4
Time in open arm before self-admin0.10.10.2-0.00.40.1-0.50.2-0.5-0.2-0.20.1-0.1-0.2-0.4-0.1-0.2-0.1
Time in open arm after self-admin0.20.20.5-0.7-0.1-0.6-0.5-0.5-0.5-0.4-0.4-0.3-0.6-0.5-0.5-0.0-0.1-0.7
Bone: periosteal estimation1.73.54.9-1.4-1.7-1.9-1.9-1.9-1.9-2.1-2.1-1.9-1.4-1.9-1.9-2.1-2.2-1.6
Bone: periosteal perimeter2.84.89.0-1.3-1.7-2.3-2.3-2.3-2.2-2.5-2.5-2.3-0.8-1.9-2.3-2.9-3.0-1.1
Bone: post-yield work0.00.00.2-0.3-0.00.10.10.10.00.10.10.1-0.00.3-0.30.20.40.0
Progressive ratio test 1 active lever presses0.20.30.8-0.9-0.7-0.5-0.6-0.5-0.6-0.3-0.3-0.3-0.6-0.4-0.6-0.10.0-0.5
Progressive ratio test 1 breakpoint0.20.30.9-0.9-0.7-0.5-0.6-0.5-0.6-0.3-0.3-0.3-0.6-0.4-0.6-0.1-0.0-0.5
Progressive ratio test 1 inactive lever presses4.86.98.0-2.7-2.8-2.7-2.7-2.6-2.7-2.6-2.6-2.6-2.8-2.7-2.6-2.3-2.1-2.8
Progressive ratio test 2 active lever presses0.20.30.8-0.9-0.8-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.7-0.5-0.4-0.2-0.0-0.5
Progressive ratio test 2 breakpoint0.20.30.8-0.9-0.8-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.7-0.4-0.4-0.2-0.0-0.5
Progressive ratio test 2 inactive lever presses0.50.81.1-1.0-1.1-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.8
Incentive Sensitization - Responses0.00.00.1-0.2-0.3-0.2-0.2-0.1-0.2-0.1-0.1-0.1-0.3-0.1-0.2-0.1-0.1-0.1
Incentive Sensitization - Breakpoint0.00.00.1-0.2-0.3-0.2-0.3-0.1-0.3-0.1-0.1-0.1-0.3-0.1-0.3-0.2-0.1-0.1
Sum of active levers in priming session hrs 5-60.10.10.4-0.6-0.4-0.2-0.5-0.1-0.5-0.2-0.2-0.2-0.7-0.2-0.5-0.00.0-0.3
Progressive ratio0.71.11.60.60.71.11.11.21.11.31.30.80.81.01.11.11.11.0
Food seeking constrained by brief footshock0.20.30.60.70.60.30.50.40.50.70.70.30.50.70.50.20.20.4
Seeking ratio, punishment vs. effort0.10.20.40.20.0-0.5-0.4-0.6-0.4-0.4-0.4-0.3-0.3-0.3-0.4-0.6-0.5-0.6
Retroperitoneal fat weight5.423.027.8-4.6-5.3-4.8-4.9-4.8-4.8-4.7-4.7-4.8-5.2-4.9-4.5-4.4-4.3-5.0
Reaction time number correct0.81.55.3-1.5-1.5-1.1-1.0-0.9-1.1-0.9-0.9-0.8-2.3-1.2-0.9-0.1-0.3-2.0
Reaction time mean minus median0.10.30.70.60.50.50.50.40.50.40.40.50.80.60.40.30.30.7
Reaction time mean minus median AUC0.10.10.40.0-0.3-0.4-0.3-0.5-0.2-0.5-0.5-0.30.2-0.2-0.3-0.6-0.7-0.2
Reaction time num false alarms0.20.30.70.30.30.60.70.60.70.40.40.50.40.40.80.60.50.6
Reaction time num false alarms AUC0.40.61.30.60.60.91.00.81.00.60.60.70.60.71.20.90.70.7
Reaction time trials correct on left0.81.55.3-1.5-1.5-1.1-1.0-0.9-1.1-0.9-0.9-0.8-2.3-1.2-0.9-0.1-0.3-2.0
Reaction time trials on left0.81.65.5-1.5-1.5-1.1-1.1-1.0-1.1-0.9-0.9-0.8-2.3-1.3-0.9-0.1-0.4-2.0
Reaction time mean0.20.20.5-0.4-0.6-0.4-0.5-0.5-0.4-0.5-0.5-0.5-0.6-0.6-0.4-0.4-0.4-0.7
Reaction time mean AUC0.20.30.6-0.5-0.6-0.4-0.5-0.4-0.4-0.5-0.5-0.5-0.7-0.6-0.5-0.3-0.3-0.8
Median of all reaction times0.30.40.8-0.5-0.7-0.5-0.6-0.5-0.6-0.6-0.6-0.6-0.9-0.7-0.5-0.4-0.5-0.9
Reaction time omissions0.40.51.2-0.0-0.4-0.6-0.8-0.6-0.8-0.9-0.9-0.7-0.5-0.8-0.6-0.9-1.1-0.7
Reaction time false alarm rate1.31.73.11.31.31.41.51.21.51.11.11.11.81.31.50.90.91.7
Reaction time premature initiation rate1.41.93.20.71.01.51.71.51.71.21.21.21.11.31.71.41.81.1
Reaction time premature initiations0.30.62.0-0.30.00.70.90.90.90.60.60.6-0.40.40.91.21.4-0.2
Std. dev. reaction times0.20.40.70.80.60.60.70.50.80.50.50.60.60.60.80.60.60.3
Reaction time trials completed0.81.65.5-1.5-1.5-1.1-1.1-1.0-1.1-0.9-0.9-0.8-2.3-1.3-0.9-0.1-0.4-2.0
Reaction time trials AUC0.91.76.0-1.6-1.6-1.2-1.1-1.0-1.1-1.0-1.0-0.9-2.4-1.3-0.9-0.1-0.4-2.1
Run reversals in cocaine runway, females0.60.61.31.00.70.71.10.71.10.60.60.70.30.51.10.70.80.2
Run reversals in cocaine runway, males0.30.31.0-1.0-0.5-0.5-0.8-0.5-0.8-0.3-0.3-0.4-0.4-0.3-0.6-0.3-0.6-0.1
Latency to leave start box in cocaine runway1.01.22.00.60.91.40.81.20.81.21.21.10.71.10.71.41.31.1
Latency to leave start box in cocaine runway, F0.10.10.6-0.10.10.50.20.30.30.30.30.4-0.30.10.10.80.60.0
Latency to leave start box in cocaine runway, M1.51.42.30.81.01.40.71.50.71.31.31.21.11.40.71.21.21.5
Std. dev. time between licks in bursts0.91.22.7-1.2-1.3-0.9-0.8-0.9-0.8-0.9-0.9-0.9-1.6-1.2-1.5-0.5-0.5-1.6
Total sessions with >9 infusions0.40.50.80.70.80.60.50.60.50.90.90.90.60.80.50.90.90.6
Short access day 1 total inactive lever presses0.20.30.60.0-0.4-0.6-0.6-0.5-0.6-0.5-0.5-0.5-0.3-0.5-0.6-0.6-0.8-0.5
Short access day 10 total inactive lever presses3.07.38.6-2.3-2.8-2.7-2.4-2.7-2.4-2.9-2.9-2.9-2.6-2.7-2.4-2.8-2.8-2.8
Short access day 1 total infusions1.11.51.91.41.21.11.41.21.41.21.21.31.01.11.31.31.30.9
Short access day 10 total infusions1.01.32.4-1.6-1.3-1.2-1.4-1.2-1.4-0.9-0.9-0.9-1.1-0.9-1.4-0.7-0.7-0.9
Short access total infusions0.00.00.1-0.2-0.1-0.1-0.1-0.1-0.10.10.10.2-0.20.0-0.20.30.4-0.1
Short access day 1 locomotion0.60.81.00.90.90.80.80.80.81.01.00.90.90.90.70.90.81.0
Short access day 10 total locomotion0.20.40.90.50.50.60.40.60.40.80.80.60.81.00.50.60.40.9
Short access total locomotion0.30.40.90.60.60.60.30.60.30.80.80.70.80.90.30.50.40.9
One hour access (0.3 mA shock)0.20.20.8-0.9-0.7-0.3-0.4-0.3-0.4-0.3-0.3-0.3-0.8-0.4-0.4-0.00.2-0.5
Compulsive drug intake0.60.71.2-0.7-0.6-0.8-0.8-0.8-0.8-1.0-1.0-0.9-1.0-1.1-0.8-0.8-0.7-1.0
One hour access (shock baseline)0.00.10.4-0.6-0.6-0.1-0.2-0.1-0.20.10.1-0.0-0.20.1-0.20.10.20.1
Social response proportion0.00.00.20.30.20.00.2-0.20.2-0.1-0.10.1-0.1-0.30.20.00.1-0.5
Social responses0.20.30.8-0.2-0.4-0.7-0.2-0.8-0.2-0.5-0.5-0.5-0.6-0.9-0.2-0.5-0.5-0.9
Social time0.00.00.10.0-0.00.00.00.00.00.10.10.1-0.2-0.00.10.10.2-0.4
Soleus weight1.74.98.0-2.8-2.4-2.3-2.5-2.3-2.5-2.2-2.2-2.3-1.7-2.0-2.0-2.2-1.8-1.7
Bone: stiffness0.30.51.2-0.1-0.4-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.4-0.7-0.8-1.1-1.1-0.5
Tibialis anterior weight0.00.10.7-0.20.10.20.20.20.20.40.40.20.20.20.90.40.60.1
Time to tail flick, vehicle, before self-admin0.20.20.70.30.10.40.50.40.50.20.20.50.70.40.60.50.50.8
Time to tail flick, vehicle, after self-admin1.21.62.51.51.41.21.31.21.31.21.21.31.61.31.31.00.91.3
Time to tail flick, test, before self-admin0.70.71.10.70.70.81.00.71.00.90.90.70.91.11.00.70.80.7
Time to tail flick, test, after self-admin0.60.72.71.61.10.61.00.51.00.40.40.51.10.50.90.00.00.8
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.4-0.4-0.5-0.5-0.6-0.5-0.5-0.5-0.6-0.7-0.5-0.6-0.6-0.5-0.9
Delta time to tail flick, test, before/after SA0.40.42.11.41.00.50.50.50.50.40.40.50.80.30.60.0-0.00.6
Tibia length8.924.644.8-2.3-3.8-5.4-5.2-5.4-5.2-5.1-5.1-5.3-3.0-4.7-5.1-6.4-6.7-3.8
Ambulatory time before self-admin2.94.45.4-1.6-1.7-2.1-2.2-2.1-2.2-2.3-2.3-2.2-1.9-2.0-2.1-2.2-2.3-2.1
Ambulatory time after self-admin1.61.93.2-1.6-1.5-1.2-1.4-1.2-1.4-1.4-1.4-1.3-1.8-1.4-1.4-1.0-0.9-1.6
Bone: tissue strength3.73.76.6-2.6-2.3-2.0-1.8-2.0-1.8-1.9-1.9-2.0-2.1-1.9-1.6-1.5-1.3-2.0
Total heroin consumption0.20.20.40.20.2-0.6-0.6-0.4-0.6-0.3-0.3-0.2-0.2-0.3-0.7-0.4-0.6-0.5
Bone: trabecular number0.10.20.50.30.50.40.60.40.50.40.40.40.60.50.30.40.50.7
Bone: trabecular spacing1.31.84.6-0.7-1.1-1.2-1.2-1.2-1.2-1.2-1.2-1.1-2.0-1.7-1.3-0.8-1.1-2.1
Bone: trabecular thickness0.10.10.8-0.9-0.5-0.1-0.2-0.1-0.1-0.1-0.1-0.20.40.2-0.2-0.20.00.7
Bone: trabecular tissue density0.71.02.41.51.21.00.91.00.90.80.81.01.20.71.10.70.61.1
Water consumed over 24 hours0.00.00.2-0.3-0.00.00.10.00.00.10.10.10.20.2-0.30.10.10.4
Number of responses in last shaping day0.00.10.20.10.2-0.1-0.40.1-0.40.00.00.20.20.1-0.40.1-0.10.3