Hub : Genes

LOC108352165

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability LOC108352165 0.2 0.13 2.7e-04 0.04 0.07 0.05 0.01 1.9e-03 1.5e-04 1.1e-03 1.5e-01
2 NAcc gene expression LOC108352165 0.12 0.07 2.4e-09 0.06 0.07 0.07 0.06 7.8e-08 3.2e-08 9.2e-09 2.2e-07
3 pVTA gene expression LOC108352165 0.37 0.14 4.1e-13 0.29 0.24 0.25 0.09 5.5e-13 5.7e-11 2.2e-11 1.5e-04
4 Adipose gene expression LOC108352165 0.09 0.05 4.3e-08 0.07 0.06 0.04 0.07 1.7e-08 5.4e-07 2.9e-05 5.3e-08
5 PL gene expression LOC108352165 0.12 0.06 9.2e-15 0.13 0.12 0.12 0.01 5.7e-14 9.6e-13 1.2e-13 4.9e-02
6 PL mRNA stability LOC108352165 0.04 0.03 7.6e-05 0.05 0.03 0.04 0.01 2.4e-06 4.2e-04 5.5e-05 3.1e-02
7 NAcc mRNA stability LOC108352165 0.03 0.02 5.3e-03 0.01 0.01 0.01 0.01 5.9e-03 1.2e-02 1.3e-02 1.2e-02
8 LHb gene expression LOC108352165 0.21 0.12 2.2e-03 0 -0.01 -0.01 -0.01 3.1e-01 8.3e-01 6.3e-01 9.4e-01
9 BLA gene expression LOC108352165 0.13 0.08 1.4e-05 0.1 0.05 0.08 -0 3.4e-06 1.7e-03 4.8e-05 9.6e-01
10 Brain gene expression LOC108352165 0.1 0.06 4.7e-08 0.09 0.08 0.08 0.09 4.8e-09 5.1e-08 1.5e-07 1.6e-08
11 RMTg mRNA stability LOC108352165 0.26 0.12 6.4e-05 0.17 0.16 0.15 0.15 3.0e-05 4.0e-05 7.9e-05 6.3e-05
12 Liver gene expression LOC108352165 0.02 0.02 4.9e-03 0.01 0.01 0.01 0 2.8e-02 5.5e-02 2.5e-02 1.4e-01
13 Brain mRNA stability LOC108352165 0.05 0.04 3.8e-04 0.04 0.03 0.04 0.04 2.4e-04 1.1e-03 1.2e-04 1.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.00.10.4-0.70.50.10.20.10.10.10.10.20.10.10.00.4
Area under the delay curve2.22.37.32.7-2.1-1.5-1.7-1.3-1.3-1.1-1.7-1.1-0.8-0.8-0.8-1.7
BMI with tail0.51.52.5-1.21.51.41.31.61.61.51.21.30.80.80.9-0.0
BMI without tail4.89.914.9-3.43.93.43.53.53.53.43.23.12.82.82.41.5
Body weight4.920.725.5-4.04.54.94.75.05.04.94.24.94.64.63.93.4
Weight adjusted by age3.84.35.4-2.22.12.02.32.12.12.22.31.81.91.92.21.8
Bone surface0.10.21.7-0.30.40.40.40.40.40.40.40.30.20.20.51.3
Bone volume0.20.31.4-0.70.70.40.40.40.40.40.40.40.40.40.31.2
Breakpoint value in progressive ratio session0.90.91.7-1.21.31.00.91.01.01.00.91.00.80.80.70.8
Number of licking bursts0.20.20.3-0.30.40.50.60.50.50.50.30.40.40.40.40.2
Context. condit. distance diff. score0.40.50.9-0.20.70.70.70.70.70.71.00.71.01.00.2-0.1
Locomotion velocity, session 14.44.88.02.7-2.8-2.1-2.1-2.2-2.2-2.2-2.0-2.2-2.4-2.4-1.4-1.3
Locomotion distance, session 12.43.04.91.5-1.5-1.7-1.7-1.6-1.6-1.6-1.7-1.6-1.9-1.9-2.2-1.7
Locomotion velocity, session 25.66.68.12.3-2.6-2.6-2.8-2.7-2.7-2.7-2.8-2.7-2.8-2.8-2.2-1.5
Locomotion distance, session 20.40.61.6-0.1-0.2-0.7-0.7-0.7-0.7-0.7-0.6-0.7-1.0-1.0-1.3-1.2
Locomotion velocity, session 31.92.23.21.7-1.8-1.5-1.6-1.4-1.4-1.4-1.3-1.4-1.5-1.5-1.7-0.7
Locomotion distance, session 34.44.86.92.2-2.4-2.2-2.2-2.2-2.2-2.2-2.1-2.2-2.1-2.1-2.6-1.6
Stereotopy head waving bouts, day 30.30.30.70.9-0.7-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.4-0.1
Stereotopy head waving duration, day 30.10.20.50.7-0.4-0.4-0.4-0.3-0.3-0.3-0.2-0.3-0.5-0.5-0.40.1
Locomotion velocity, session 71.21.32.11.5-1.3-1.1-1.0-1.1-1.1-1.1-0.8-1.1-1.3-1.3-1.3-0.7
Locomotion distance, session 73.03.85.81.9-1.6-2.0-1.9-2.0-2.0-2.0-1.9-2.0-2.1-2.1-2.4-0.9
Stereotopy head waving bouts, day 70.30.40.6-0.00.40.70.60.70.70.70.60.70.70.70.50.2
Stereotopy head waving duration, day 70.70.81.3-0.30.51.01.01.11.11.11.21.11.01.00.80.3
Locomotion velocity, session 80.40.52.61.6-1.0-0.4-0.6-0.4-0.4-0.4-0.5-0.4-0.5-0.5-0.6-0.3
Locomotion distance, session 80.20.30.9-0.71.00.50.50.40.40.40.60.40.40.4-0.7-0.4
Degree of sensitization distance1.01.02.3-1.31.50.90.90.90.90.91.00.90.80.81.00.8
Degree of sensitization stereotypy0.70.81.1-0.50.81.00.91.01.01.00.81.01.01.00.80.5
Conditioned locomotion5.16.08.2-2.62.92.52.42.52.52.52.52.62.62.61.61.5
Cocaine response after cond. corrected0.10.10.30.5-0.4-0.4-0.3-0.4-0.4-0.4-0.1-0.4-0.4-0.4-0.4-0.3
Cocaine response after cond. not corrected0.80.91.31.1-1.1-1.0-0.9-1.0-1.0-1.0-0.7-1.0-1.0-1.0-0.8-0.4
Cocaine response before conditioning1.01.21.51.2-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.2-1.2-0.8-0.2
Saline control response3.14.14.9-2.02.02.02.12.02.02.01.92.12.22.21.81.8
Bone: connectivity density0.10.10.30.1-0.1-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.6-0.6-0.5-0.0
Bone: cortical apparent density2.83.74.41.4-1.6-2.0-2.1-2.0-2.0-2.0-2.0-2.0-2.1-2.1-2.0-1.2
Bone: cortical area7.110.612.3-3.03.03.43.33.43.43.43.53.33.53.53.22.5
Bone: cortical porosity0.60.72.4-0.70.60.70.60.70.70.70.50.70.70.71.51.5
Bone: cortical porosity0.80.92.4-0.70.70.90.80.90.90.90.80.90.90.91.51.4
Bone: cortical thickness6.09.811.3-3.32.93.23.23.23.23.23.33.23.43.43.21.8
Bone: cortical thickness2.02.33.2-1.31.21.61.51.61.61.61.51.61.81.81.50.7
Bone: cortical tissue density3.34.35.01.5-1.8-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.2-1.2
Condit. Reinf. active minus inactive responses2.73.04.3-2.02.11.61.81.81.81.81.81.81.91.91.20.6
Condit. Reinf. active-inactive response ratio1.31.42.3-1.31.51.11.21.21.21.21.21.21.41.40.60.2
Condit. Reinf. active responses4.65.68.3-2.92.82.32.52.42.42.42.42.42.42.41.71.3
Condit. Reinf. inactive responses1.11.32.5-1.61.31.11.31.11.11.11.11.11.01.00.80.8
Incentive salience index mean2.22.73.8-1.91.91.61.81.71.71.71.71.71.71.71.20.5
Condit. Reinf. lever presses0.10.10.3-0.50.50.30.40.30.30.30.40.30.30.30.2-0.4
Condit. Reinf. active minus inactive responses1.31.62.6-0.50.71.31.31.31.31.31.61.41.61.61.2-0.9
Condit. Reinf. active-inactive response ratio2.62.73.3-1.51.41.81.71.81.81.81.81.81.71.71.80.2
Condit. Reinf. active responses0.40.62.3-0.20.30.70.60.70.70.70.90.80.90.90.4-1.5
Condit. Reinf. inactive responses0.60.72.40.7-0.7-0.8-0.8-0.8-0.8-0.8-0.6-0.6-0.7-0.7-1.0-1.6
Condit. Reinf. lever presses0.30.40.7-0.70.90.70.60.70.70.70.60.70.50.50.1-0.8
Condit. Reinf. lever reinforcers received0.50.73.2-0.20.40.70.60.70.70.70.90.80.90.90.1-1.8
Conditioned reinforcement - actives0.60.61.7-1.20.80.70.90.60.60.51.00.40.10.11.30.1
Conditioned reinforcement - inactives2.22.43.3-1.61.71.81.41.71.71.51.51.41.21.21.81.6
Conditioned locomotion1.11.43.5-1.91.51.21.21.11.11.01.20.80.50.51.41.1
Patch foraging indifference point 0 sec0.61.02.9-1.71.61.00.71.01.00.80.50.80.70.70.31.1
Patch foraging indifference point AUC0.10.10.5-0.40.50.20.00.30.30.2-0.20.30.20.2-0.00.7
Delay disc. indifference point, 0s delay0.20.20.70.9-0.6-0.10.2-0.0-0.00.10.20.20.50.50.5-0.7
Delay disc. indifference point, 16s delay1.21.22.71.7-1.1-1.2-1.4-1.2-1.2-0.8-1.5-0.7-0.4-0.4-0.9-1.3
Delay disc. indifference point, 2s delay0.30.42.01.4-1.0-0.5-0.6-0.3-0.3-0.1-0.6-0.3-0.0-0.00.4-0.7
Delay disc. indifference point, 24s delay5.75.57.42.6-2.5-2.7-2.7-2.6-2.6-2.3-2.7-2.2-2.0-2.0-1.5-1.6
Delay disc. indifference point, 4s delay0.50.53.41.8-1.2-0.6-0.7-0.2-0.2-0.1-0.8-0.10.20.20.1-0.9
Delay disc. indifference point, 8s delay2.22.37.62.8-2.3-1.4-1.4-1.2-1.2-1.2-1.4-1.2-1.1-1.1-0.7-1.6
Indifference point function ln k1.11.51.81.0-1.1-1.2-1.1-1.3-1.3-1.2-1.1-1.3-1.3-1.3-1.3-1.0
Indifference point function log k1.11.51.81.0-1.1-1.2-1.1-1.3-1.3-1.2-1.1-1.3-1.3-1.3-1.3-1.0
Patch foraging total patch changes 0 sec0.61.03.0-1.71.71.10.71.11.10.80.40.90.70.70.20.9
Patch foraging total patch changes 12 sec0.70.92.7-1.71.70.70.20.90.90.7-0.10.90.70.70.01.2
Patch foraging total patch changes 18 sec0.20.20.8-0.50.90.4-0.00.40.40.3-0.30.50.40.4-0.80.0
Patch foraging total patch changes 24 sec1.92.43.2-1.61.81.71.41.81.81.51.21.51.51.51.31.1
Patch foraging total patch changes 6 sec1.32.05.6-2.42.11.21.01.21.21.10.61.30.90.91.12.0
Patch foraging time to switch 0 sec1.01.52.41.6-1.6-1.3-1.3-1.3-1.3-1.1-1.4-1.1-0.9-0.9-1.0-1.2
Patch foraging water rate 0 sec4.36.99.6-2.83.12.82.72.82.82.72.72.72.42.41.82.0
Patch foraging water rate 12 sec0.30.40.9-0.90.90.70.80.60.60.40.90.30.10.10.8-0.5
Patch foraging water rate 18 sec1.72.34.4-1.92.11.51.71.51.51.51.81.31.01.01.11.1
Patch foraging water rate 24 sec4.05.611.1-2.83.32.42.42.42.42.42.42.52.22.20.91.3
Patch foraging water rate 6 sec0.20.30.7-0.60.60.70.80.60.60.50.80.30.40.40.6-0.3
Seeking ratio, delayed vs. immediate footshock1.01.23.3-1.00.71.21.21.11.11.11.30.70.80.81.80.8
Distance traveled before self-admin0.80.81.6-0.30.51.01.00.90.91.11.21.10.90.91.20.2
Distance traveled after self-admin0.60.71.5-1.21.20.81.10.70.70.81.10.60.60.60.20.2
Extensor digitorum longus weight0.10.21.1-1.01.10.30.30.30.30.30.20.40.10.1-0.30.3
Bone: elastic displacement2.12.44.9-2.21.81.51.51.51.51.51.61.51.31.31.11.0
Bone: elastic work7.69.913.6-3.73.43.23.13.23.23.23.03.22.92.92.92.8
Bone: endosteal estimation0.00.00.20.30.2-0.0-0.0-0.0-0.0-0.0-0.2-0.1-0.1-0.1-0.30.4
Bone: endosteal perimeter0.61.22.5-0.50.91.11.11.11.11.11.01.00.90.91.41.6
Epididymis fat weight1.53.54.6-1.92.21.92.01.91.92.12.02.01.81.81.41.1
Delta time in closed arm before/after self-admin0.10.10.5-0.00.10.40.20.30.30.40.30.10.20.20.70.3
Delta time in open arm before/after self-admin0.50.50.9-0.70.90.70.50.90.90.70.50.90.70.7-0.0-0.1
Diff in mean of infusions in LGA sessions0.00.00.1-0.00.20.1-0.20.30.30.2-0.10.1-0.1-0.1-0.40.2
Delay discount exponential model param2.93.09.0-3.02.31.82.01.51.51.32.11.31.11.11.11.6
Extinction: sum of active levers before priming1.21.21.81.0-1.0-1.0-1.1-1.1-1.1-1.1-1.1-1.0-1.3-1.3-0.9-1.3
Active lever presses in extinction session 60.30.30.5-0.50.70.60.40.70.70.70.40.60.40.40.20.5
Bone: final force6.09.711.6-2.83.13.33.33.33.33.33.23.43.33.32.62.1
Bone: final moment7.111.413.3-3.23.43.63.53.63.63.63.43.63.53.52.82.4
Food consumed during 24 hour testing period1.11.31.9-0.91.31.21.31.21.21.21.41.11.21.20.50.7
Glucose3.34.96.31.9-2.2-2.5-2.5-2.4-2.4-2.4-2.1-2.4-2.4-2.4-1.5-1.3
Heart weight0.60.91.7-1.31.31.00.80.90.90.90.81.00.80.80.21.3
Delay discount hyperbolic model param2.62.78.5-2.92.21.61.91.31.31.22.01.20.90.90.91.6
Intermittent access intake day 1-15 change0.10.10.30.1-0.00.20.30.30.30.30.40.20.20.20.60.0
Intermittent access intake escalation0.20.20.5-0.10.30.40.50.50.50.50.60.40.40.40.70.2
Intermittent access intake escalation 20.40.40.8-0.60.50.70.70.70.70.70.80.50.40.40.90.6
Intermitt. access day 1 inactive lever presses2.22.43.3-1.41.71.81.61.71.71.71.61.61.51.50.91.2
Intermitt. access day 15 inactive lever presses2.02.23.0-1.61.61.61.71.61.61.51.71.41.51.51.30.6
Intermitt. access escalation Index2.01.72.2-1.41.41.31.41.31.31.41.41.31.51.50.90.9
Intermittent access day 1 total infusions0.50.61.5-1.21.00.70.70.70.70.60.70.50.30.31.21.0
Intermittent access day 15 total infusions1.01.12.4-1.21.21.01.01.01.01.01.00.80.70.71.51.0
Intermittent access terminal intake (last 3 days)1.41.54.1-1.41.21.21.31.21.21.11.30.90.80.82.01.2
Intermittent access total infusions1.01.12.2-1.31.31.11.11.01.00.91.00.70.60.61.51.1
Intermittent access day 1 locomotion1.41.42.9-1.71.71.21.01.21.21.20.91.00.80.81.01.5
Intermittent access day 15 total locomotion0.70.71.7-1.10.90.80.80.80.80.80.80.60.40.41.31.3
Intermittent access total locomotion1.31.42.7-1.61.61.21.11.21.21.21.01.00.80.81.01.3
Intermittent access standard deviation0.50.52.21.5-1.2-0.6-0.5-0.3-0.3-0.4-0.4-0.6-0.6-0.60.1-1.1
Left kidney weight0.20.50.80.3-0.30.70.50.70.70.70.60.90.90.90.80.7
Right kidney weight0.20.61.30.20.10.70.40.80.80.90.41.01.21.20.50.6
Cocaine induced anxiety5.36.17.5-2.22.52.72.42.72.72.72.42.52.52.52.31.6
Post-drug Anxiety1.31.52.7-0.51.41.30.71.41.41.70.51.61.61.60.00.7
Baseline Anxiety7.98.411.73.2-3.0-3.0-3.1-2.9-2.9-2.8-3.2-2.6-2.6-2.6-3.4-2.1
Tail length7.422.425.4-4.74.94.94.94.94.94.94.64.85.05.04.13.7
Length with tail3.914.218.1-3.03.24.03.83.93.93.93.44.04.24.23.63.5
Length without tail0.10.20.80.8-0.90.1-0.20.10.10.2-0.20.40.50.50.20.9
Times rat made contact with spout1.51.83.9-2.01.71.31.51.31.31.31.41.21.01.00.71.1
Lifetime Intake0.30.31.2-0.70.70.50.60.50.50.40.60.30.10.11.10.6
Liver weight, left0.10.20.80.9-0.8-0.3-0.2-0.3-0.3-0.4-0.1-0.3-0.3-0.30.20.5
Liver weight, right2.94.86.6-1.91.72.32.22.32.32.32.12.42.62.62.01.7
Locomotor activity0.40.71.21.1-1.0-0.7-0.7-0.7-0.7-1.0-0.9-0.9-0.7-0.7-0.6-1.1
Locomotor testing distance0.30.41.20.9-0.8-0.4-0.4-0.4-0.4-0.7-0.6-0.7-0.6-0.6-0.4-1.1
Locomotor testing rearing0.20.20.7-0.30.50.60.40.60.60.30.30.40.50.5-0.2-0.9
Locomotion in novel chamber0.10.20.4-0.40.70.30.10.30.30.5-0.00.50.40.4-0.30.6
Locomotion in novel chamber post-restriction1.01.23.5-1.71.40.91.00.80.80.80.90.90.50.50.91.9
Fecal boli incidents, locomotor time 10.80.92.00.2-0.5-0.8-0.4-0.9-0.9-1.0-0.4-1.2-1.4-1.4-0.2-1.3
Change in fecal boli incidents, locomotor task3.63.45.81.8-1.9-2.0-2.4-1.8-1.8-1.9-2.4-1.9-1.6-1.6-1.80.1
Time >=10cm from walls, locomotor time 10.10.10.60.5-0.20.00.0-0.0-0.0-0.10.1-0.1-0.3-0.3-0.2-0.8
Bouts of movement, locomotor time 12.32.53.51.4-1.4-1.5-1.7-1.4-1.4-1.7-1.8-1.9-1.8-1.8-1.5-1.1
Total resting periods, locomotor time 12.93.14.51.4-1.5-1.7-1.9-1.7-1.7-1.9-1.9-2.1-2.1-2.1-1.7-0.9
Rest time, locomotor task time 10.30.31.0-0.0-0.2-0.1-0.5-0.4-0.4-0.7-0.5-0.9-1.0-1.0-0.0-0.1
Distance moved, locomotor task time 10.91.01.7-0.70.80.80.81.01.01.20.71.31.31.30.81.0
Vertical activity count, locomotor time 10.91.01.5-0.90.90.91.10.90.91.01.01.21.21.21.00.3
Time >=10cm from walls, locomotor time 20.10.10.4-0.50.60.20.00.10.10.40.00.50.30.30.70.3
Bouts of movement, locomotor time 21.71.82.51.6-1.4-1.4-1.3-1.2-1.2-1.4-1.5-1.4-1.2-1.2-1.3-1.2
Total resting periods, locomotor time 21.01.11.61.2-1.1-1.1-0.9-0.9-0.9-1.1-1.1-1.2-1.0-1.0-1.0-1.0
Rest time, locomotor task time 20.10.10.30.3-0.2-0.3-0.4-0.2-0.2-0.3-0.4-0.6-0.4-0.4-0.00.0
Distance moved, locomotor task time 20.40.50.9-0.40.50.70.50.60.60.80.30.90.90.90.90.6
Vertical activity count, locomotor time 20.40.40.7-0.20.50.80.70.60.60.60.50.80.80.80.6-0.3
Light reinforcement 12.13.86.5-2.52.42.02.12.02.01.92.31.81.61.61.80.2
Light reinforcement 22.83.76.1-2.01.81.92.21.81.81.82.51.92.02.02.20.7
Bone: marrow area0.00.00.10.30.2-0.0-0.0-0.0-0.0-0.0-0.2-0.1-0.1-0.1-0.30.3
Bone: maximum diameter1.83.34.0-1.01.31.91.91.91.91.91.91.92.02.01.81.8
Bone: maximum force5.810.111.2-3.13.33.33.33.33.33.33.23.33.23.22.72.4
Bone: maximum moment6.811.713.4-3.53.73.63.53.63.63.63.43.53.33.32.92.8
Mean time between licks in bursts1.31.92.81.5-1.3-1.4-1.5-1.4-1.4-1.4-1.3-1.3-1.4-1.4-1.7-0.7
Mean num. licks in bursts0.30.31.3-1.10.90.40.50.40.40.40.50.50.50.50.10.7
Cd content in liver1.21.33.41.2-1.0-1.0-1.3-1.0-1.0-1.1-1.1-1.0-0.9-0.9-1.8-1.1
Co content in liver0.00.00.2-0.50.3-0.1-0.1-0.1-0.1-0.10.0-0.2-0.1-0.1-0.3-0.1
Cu content in liver0.20.20.6-0.60.50.30.30.30.30.30.30.30.40.40.70.8
Fe content in liver0.50.71.00.8-0.5-1.0-1.0-0.9-0.9-0.9-0.8-0.9-0.7-0.7-1.0-0.2
K content in liver2.72.73.5-1.91.81.71.71.61.61.61.61.61.51.51.61.7
Mg content in liver0.20.21.1-1.00.90.40.50.30.30.30.40.30.10.10.40.6
Mn content in liver0.20.20.50.1-0.00.50.50.40.40.30.70.40.70.70.50.5
Na content in liver0.00.00.30.2-0.4-0.00.2-0.1-0.1-0.10.30.00.20.20.5-0.1
Rb content in liver1.21.52.5-1.51.61.21.21.21.21.31.21.31.21.20.90.5
Se content in liver0.40.50.9-0.40.70.70.50.70.70.60.60.61.01.00.70.4
Sr content in liver0.10.10.60.1-0.3-0.2-0.3-0.2-0.2-0.3-0.7-0.3-0.4-0.40.20.4
Zn content in liver0.00.10.30.0-0.3-0.1-0.0-0.1-0.1-0.2-0.2-0.2-0.1-0.10.60.1
Bone: minimum diameter4.27.98.5-2.72.82.92.82.92.92.92.82.92.72.72.92.6
Time in familiar zone, hab. session 10.00.00.1-0.30.3-0.2-0.3-0.2-0.2-0.2-0.1-0.20.00.0-0.1-0.1
Time in novel zone, hab. session 10.10.10.50.7-0.50.10.10.10.10.10.30.1-0.0-0.0-0.0-0.2
Total zone transitions, hab. session 10.20.31.20.2-0.0-0.5-0.6-0.4-0.4-0.4-0.7-0.4-0.3-0.3-1.1-0.7
Total locomotion distance, hab. session 10.40.61.5-0.91.20.70.70.80.80.80.90.80.80.80.3-0.1
Locomotion velocity, hab. session 10.50.71.8-1.11.30.80.80.80.80.80.70.80.90.90.40.2
Time in familiar zone, hab. session 20.20.20.50.3-0.2-0.4-0.4-0.4-0.4-0.4-0.2-0.4-0.4-0.40.1-0.7
Time in novel zone, hab. session 20.10.10.50.5-0.4-0.2-0.3-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.70.0
Total zone transitions, hab. session 20.20.20.8-0.60.5-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.5-0.9-0.8
Total locomotion distance, hab. session 20.70.93.1-1.81.60.80.90.80.80.81.00.80.70.70.1-0.2
Locomotion velocity, hab. session 21.01.33.9-2.01.71.11.21.11.11.11.21.10.90.90.20.0
Novel to familiar place preference ratio2.82.86.6-2.62.31.61.51.61.61.61.51.61.71.71.10.5
Novelty place preference2.62.65.9-2.42.11.51.51.61.61.61.41.61.71.71.10.5
Time in novel zone, NPP test2.22.35.5-2.32.11.41.31.51.51.51.31.51.61.61.00.4
Total zone transitions, NPP test0.20.31.60.0-0.0-0.5-0.5-0.4-0.4-0.4-0.3-0.4-0.5-0.5-1.3-0.9
Total locomotion distance, NPP test0.40.52.2-1.51.40.50.50.50.50.50.70.50.20.2-0.5-0.6
Locomotion velocity, NPP test0.50.62.5-1.61.40.60.70.70.70.70.80.70.40.4-0.4-0.5
Intraocular pressure0.50.82.1-1.31.40.70.50.80.81.00.41.00.90.90.30.5
Delta distance traveled before/after self-admin0.10.10.4-0.60.60.10.10.00.0-0.00.1-0.10.20.2-0.6-0.3
Delta ambulatory time before/after self-admin0.20.31.0-0.20.1-0.5-0.4-0.5-0.5-0.6-0.5-0.6-0.4-0.4-1.0-0.5
Parametrial fat weight2.24.35.7-2.42.32.12.02.02.02.01.82.11.81.82.32.4
Pavlov. Cond. lever latency0.91.12.11.4-0.8-1.0-1.0-1.1-1.1-1.1-0.7-1.0-1.0-1.0-1.0-1.4
Pavlov. Cond. magazine entry latency2.43.24.2-1.51.41.91.81.81.81.81.61.71.91.92.11.7
Pavlov. Cond. change in total contacts0.20.31.1-1.10.70.40.40.40.40.40.20.40.50.50.20.5
Pavlov. Cond. index score3.84.85.4-2.22.02.32.22.32.32.31.92.22.32.32.21.9
Pavlov. Cond. latency score2.83.54.1-1.91.61.91.92.02.02.01.61.91.91.92.01.8
Pavlov. Cond. lever contacts1.11.32.8-1.71.11.11.11.21.21.20.81.11.01.01.11.2
Pavlov. Cond. magazine entry number1.82.32.81.3-1.3-1.5-1.5-1.6-1.6-1.6-1.2-1.5-1.6-1.6-1.6-1.7
Pavlov. Cond. intertrial magazine entries0.10.10.8-0.90.70.20.30.20.20.20.30.20.20.20.1-0.0
Pavlov. Cond. lever-magazine prob. diff.4.15.15.7-2.32.12.32.32.42.42.42.02.32.42.42.31.8
Pavlov. Cond. response bias2.12.63.0-1.71.51.61.61.71.71.71.31.61.61.61.61.7
Pavlov. Cond. lever latency1.01.33.01.6-1.7-1.1-1.2-1.2-1.2-1.2-1.1-1.2-1.0-1.0-0.70.1
Pavlov. Cond. magazine entry latency0.70.81.50.8-0.4-1.0-1.0-1.0-1.0-1.0-1.2-0.8-0.7-0.7-1.2-0.6
Pavlov. Cond. change in total contacts0.10.11.2-0.10.2-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.1-0.1-0.5-1.1
Pavlov. Cond. index score0.10.10.5-0.40.70.10.10.10.10.1-0.00.20.20.2-0.3-0.5
Pavlov. Cond. latency score0.10.10.5-0.40.70.20.20.20.20.20.10.30.30.3-0.1-0.4
Pavlov. Cond. lever contacts1.31.73.5-1.71.91.41.41.41.41.41.31.41.11.10.70.0
Pavlov. Cond. magazine entry number0.40.51.2-0.40.20.80.80.80.80.80.80.60.60.61.10.9
Pavlov. Cond. intertrial magazine entries1.62.13.3-1.21.21.61.61.61.61.61.81.51.31.31.30.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.20.5-0.1-0.1-0.1-0.1-0.1-0.10.0-0.0-0.0-0.5-0.6
Pavlov. Cond. response bias0.30.41.1-0.81.10.50.50.50.50.50.50.60.50.5-0.0-0.7
Time in closed arm before self-admin0.80.91.81.0-0.9-1.1-1.2-0.9-0.9-0.9-1.3-0.7-0.7-0.7-1.0-0.1
Time in closed arm after self-admin1.31.32.91.4-1.1-1.2-1.6-1.2-1.2-0.9-1.7-1.0-0.8-0.8-0.90.0
Time in open arm before self-admin0.10.20.40.2-0.7-0.30.2-0.4-0.4-0.40.4-0.3-0.3-0.30.5-0.5
Time in open arm after self-admin0.00.00.1-0.20.10.20.20.30.30.10.30.1-0.1-0.1-0.1-0.4
Bone: periosteal estimation2.14.34.8-1.82.12.22.22.22.22.22.22.12.12.11.81.9
Bone: periosteal perimeter3.15.26.6-1.81.92.32.32.32.32.32.32.32.32.32.52.6
Bone: post-yield work0.10.10.3-0.60.40.00.00.00.00.00.10.1-0.4-0.4-0.30.2
Progressive ratio test 1 active lever presses1.01.02.0-1.41.31.11.20.90.90.91.30.70.40.41.20.6
Progressive ratio test 1 breakpoint1.11.22.5-1.61.41.21.31.01.00.91.30.70.50.51.30.7
Progressive ratio test 1 inactive lever presses4.04.45.7-2.02.22.42.32.32.32.22.32.11.91.92.01.1
Progressive ratio test 2 active lever presses0.70.81.8-1.21.00.90.80.80.80.80.80.60.40.41.31.0
Progressive ratio test 2 breakpoint0.70.81.7-1.11.10.90.90.90.90.80.90.70.50.51.30.9
Progressive ratio test 2 inactive lever presses0.80.92.1-1.00.91.00.91.01.01.01.00.70.70.71.41.1
Incentive Sensitization - Responses0.00.00.3-0.1-0.00.20.20.10.10.00.2-0.1-0.1-0.10.50.2
Incentive Sensitization - Breakpoint0.00.00.3-0.0-0.10.20.20.10.10.00.2-0.1-0.2-0.20.60.2
Sum of active levers in priming session hrs 5-60.20.20.6-0.60.60.40.70.30.30.40.80.50.30.30.2-0.2
Progressive ratio0.30.41.00.2-0.2-0.7-0.7-0.8-0.8-0.6-0.7-1.0-0.6-0.6-0.6-0.4
Food seeking constrained by brief footshock0.20.30.60.6-0.4-0.1-0.4-0.2-0.2-0.3-0.3-0.5-0.7-0.7-0.5-0.8
Seeking ratio, punishment vs. effort0.10.10.30.3-0.20.50.40.50.50.30.40.50.10.10.1-0.2
Retroperitoneal fat weight6.721.926.0-4.65.05.14.94.94.94.94.74.94.74.73.83.3
Reaction time number correct0.50.72.5-1.21.61.00.90.80.80.80.80.70.10.10.20.0
Reaction time mean minus median0.20.20.40.5-0.6-0.5-0.4-0.5-0.5-0.5-0.5-0.4-0.4-0.4-0.3-0.0
Reaction time mean minus median AUC0.10.10.30.0-0.00.40.30.40.40.30.20.50.40.40.60.1
Reaction time num false alarms0.20.30.70.4-0.3-0.5-0.8-0.5-0.5-0.4-0.9-0.4-0.5-0.5-0.5-0.3
Reaction time num false alarms AUC0.50.61.50.7-0.6-0.7-1.1-0.7-0.7-0.7-1.2-0.7-0.8-0.8-0.9-0.3
Reaction time trials correct on left0.50.72.5-1.21.61.00.90.80.80.80.80.70.10.10.20.0
Reaction time trials on left0.50.72.5-1.21.61.00.90.90.90.80.90.70.20.20.2-0.0
Reaction time mean0.10.20.3-0.10.30.40.50.40.40.40.30.50.60.6-0.20.0
Reaction time mean AUC0.10.20.4-0.20.40.40.50.40.40.40.40.50.60.6-0.10.0
Median of all reaction times0.20.20.5-0.20.40.50.50.50.50.60.40.60.70.7-0.30.0
Reaction time omissions0.20.30.50.00.20.50.70.50.50.60.70.70.50.50.3-0.4
Reaction time false alarm rate0.91.32.41.3-1.4-1.2-1.5-1.1-1.1-1.0-1.5-1.0-0.9-0.9-0.9-0.4
Reaction time premature initiation rate1.21.72.90.7-0.9-1.4-1.6-1.4-1.4-1.3-1.7-1.2-1.2-1.2-1.5-1.0
Reaction time premature initiations0.50.61.4-0.00.1-0.7-0.9-0.7-0.7-0.7-1.0-0.7-0.9-0.9-1.2-0.9
Std. dev. reaction times0.40.60.90.9-0.7-0.7-0.8-0.7-0.7-0.7-0.9-0.6-0.6-0.6-1.0-0.7
Reaction time trials completed0.50.72.5-1.21.61.00.90.90.90.80.90.70.20.20.2-0.0
Reaction time trials AUC0.60.83.0-1.31.71.11.00.90.90.90.90.80.20.20.30.1
Run reversals in cocaine runway, females0.60.62.11.0-0.5-0.4-0.9-0.5-0.5-0.5-1.0-0.4-0.5-0.5-1.5-0.9
Run reversals in cocaine runway, males0.60.62.4-1.10.70.50.70.40.40.40.70.30.20.21.61.5
Latency to leave start box in cocaine runway0.90.91.60.4-0.7-1.2-0.8-1.3-1.3-1.1-0.7-0.9-1.0-1.0-1.2-0.4
Latency to leave start box in cocaine runway, F0.20.20.6-0.1-0.0-0.6-0.5-0.5-0.5-0.4-0.4-0.1-0.2-0.2-0.80.2
Latency to leave start box in cocaine runway, M0.50.51.1-0.3-0.2-0.7-0.3-0.9-0.9-0.7-0.2-0.8-1.1-1.1-0.8-0.1
Std. dev. time between licks in bursts0.80.91.8-1.01.41.00.91.01.01.01.31.01.01.0-0.2-0.0
Total sessions with >9 infusions0.80.91.61.1-1.1-0.8-0.6-0.9-0.9-0.9-0.5-1.1-1.3-1.30.1-0.9
Short access day 1 total inactive lever presses0.20.30.5-0.50.40.60.60.50.50.50.70.40.30.30.60.4
Short access day 10 total inactive lever presses4.04.45.2-1.92.02.32.12.32.32.32.22.22.32.31.31.6
Short access day 1 total infusions1.41.42.01.4-1.2-1.1-1.2-1.1-1.1-1.1-1.3-1.3-1.4-1.4-0.9-1.0
Short access day 10 total infusions0.70.81.8-1.21.00.91.00.90.90.71.10.60.40.41.30.9
Short access total infusions0.10.10.3-0.0-0.0-0.10.0-0.1-0.1-0.20.0-0.3-0.5-0.50.3-0.1
Short access day 1 locomotion0.30.40.80.5-0.6-0.5-0.6-0.5-0.5-0.5-0.5-0.8-0.9-0.90.40.1
Short access day 10 total locomotion0.20.20.30.3-0.4-0.4-0.5-0.3-0.3-0.3-0.5-0.4-0.6-0.6-0.20.5
Short access total locomotion0.80.81.90.7-0.9-0.9-0.8-0.8-0.8-0.8-0.8-1.1-1.4-1.4-0.0-0.0
One hour access (0.3 mA shock)1.61.93.1-1.81.81.31.51.31.31.31.51.21.11.11.40.8
Compulsive drug intake1.01.01.8-1.11.30.90.80.90.91.00.81.31.31.30.60.6
One hour access (shock baseline)0.30.40.9-0.90.60.60.80.50.50.40.80.20.00.01.00.5
Social response proportion0.10.10.70.5-0.2-0.2-0.4-0.0-0.00.0-0.40.0-0.1-0.1-0.6-0.9
Social responses0.20.30.6-0.10.50.60.20.70.70.60.10.60.80.80.1-0.4
Social time0.10.11.20.10.0-0.1-0.2-0.1-0.1-0.0-0.1-0.1-0.2-0.2-0.1-1.1
Soleus weight1.95.710.9-3.32.82.32.42.32.32.42.12.42.02.02.41.8
Bone: stiffness0.50.81.2-0.30.51.00.91.01.01.01.01.01.11.10.70.4
Tibialis anterior weight0.00.10.6-0.40.3-0.2-0.2-0.2-0.2-0.1-0.4-0.1-0.3-0.3-0.30.8
Time to tail flick, vehicle, before self-admin0.20.20.5-0.70.60.30.40.40.40.30.30.50.50.50.10.6
Time to tail flick, vehicle, after self-admin1.92.02.91.4-1.6-1.4-1.6-1.5-1.5-1.5-1.7-1.3-1.6-1.6-0.8-0.4
Time to tail flick, test, before self-admin0.00.00.10.0-0.1-0.1-0.3-0.1-0.1-0.1-0.2-0.1-0.4-0.4-0.00.3
Time to tail flick, test, after self-admin0.10.10.50.7-0.20.2-0.20.20.20.2-0.20.30.50.50.1-0.5
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.00.10.1-0.2-0.1-0.1-0.1-0.3-0.1-0.2-0.2-0.00.1
Delta time to tail flick, test, before/after SA0.50.41.71.3-1.0-0.4-0.5-0.4-0.4-0.4-0.5-0.5-0.1-0.1-0.3-1.1
Tibia length8.223.229.1-2.63.15.35.35.35.35.35.05.25.45.45.32.9
Ambulatory time before self-admin2.12.23.1-0.81.11.61.61.51.51.71.81.71.61.61.50.6
Ambulatory time after self-admin0.70.71.2-0.91.10.81.10.80.80.91.11.00.80.80.30.1
Bone: tissue strength2.72.65.5-2.32.21.61.61.61.61.61.51.61.41.41.00.8
Total heroin consumption0.20.21.30.4-0.40.40.30.20.20.10.50.10.20.20.7-1.1
Bone: trabecular number0.10.10.30.2-0.3-0.4-0.3-0.4-0.4-0.4-0.4-0.3-0.5-0.5-0.30.0
Bone: trabecular spacing0.81.01.8-0.10.81.11.01.11.11.11.31.01.31.30.4-0.9
Bone: trabecular thickness0.10.21.1-1.00.40.10.20.10.10.1-0.10.20.10.10.30.8
Bone: trabecular tissue density0.71.12.21.5-1.4-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.7-0.7-0.9-0.6
Water consumed over 24 hours0.00.00.1-0.40.1-0.00.1-0.0-0.0-0.00.20.0-0.0-0.0-0.00.3
Number of responses in last shaping day1.21.33.3-0.90.61.11.51.11.10.91.70.90.70.71.80.3