Hub : Genes

LOC108352132

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XR_010055452.1 0.04 0.03 6.1e-04 0.05 0.04 0.04 0.04 1.5e-05 1.9e-04 1.3e-04 8.0e-05
2 Brain isoform ratio XR_001840282.3 0.03 0.02 7.1e-03 0.01 0.01 0 0.01 2.1e-02 1.9e-02 1.2e-01 7.3e-02
3 Liver gene expression LOC108352132 0.03 0.02 2.7e-04 0.03 0.02 0.01 0.02 1.7e-04 1.3e-03 8.5e-03 9.4e-04
4 Brain intron excision ratio chr10_84822920_84823665 0.02 0.02 9.3e-03 0.01 0.02 0.01 0.01 5.2e-02 4.7e-03 1.5e-02 1.6e-02
5 Adipose gene expression LOC108352132 0.05 0.03 3.0e-06 0.05 0.04 0.05 0.04 3.6e-06 1.8e-05 4.1e-06 1.0e-05
6 Brain isoform ratio XR_010055454.1 0.05 0.03 2.3e-05 0.03 0.05 0.04 0.03 4.3e-04 2.2e-05 9.4e-05 5.2e-04
7 PL gene expression LOC108352132 0.02 0.01 6.4e-03 0.02 0.02 0 0.01 3.7e-03 4.1e-03 9.1e-02 1.9e-02
8 pVTA gene expression LOC108352132 0.06 0.04 2.8e-05 0.06 0.06 0.03 0.06 1.0e-05 1.7e-05 1.7e-03 2.2e-05
9 OFC gene expression LOC108352132 0.65 0.17 3.9e-07 0.21 0.29 0.23 0.03 1.1e-05 1.3e-07 2.8e-06 8.0e-02
10 Adipose alternative TSS XR_001840282.3 0.02 0.02 2.3e-03 0.03 0.01 0.02 0.02 1.7e-04 1.7e-02 2.4e-03 2.1e-03
11 Brain mRNA stability LOC108352132 0.02 0.01 1.0e-02 0.02 0.02 0.01 0.01 6.3e-03 3.2e-03 1.4e-02 1.8e-02
12 Brain isoform ratio XR_010055452.1 0.04 0.02 1.1e-04 0.01 0.04 0.04 0.03 1.5e-02 9.3e-05 2.2e-04 1.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.91.73.7-1.9-1.41.8-1.21.60.51.40.91.5-1.1-0.50.1
Area under the delay curve1.01.52.5-0.4-1.20.8-1.30.71.31.31.41.4-1.6-1.5-1.4
BMI with tail1.96.710.22.63.2-3.03.2-2.4-3.0-2.6-2.4-0.32.12.52.5
BMI without tail0.63.35.91.82.2-2.42.2-1.8-2.1-1.7-1.60.31.31.71.8
Body weight3.716.125.94.85.0-5.14.9-3.9-4.4-3.7-3.60.53.33.43.2
Weight adjusted by age0.20.66.80.1-0.20.2-0.10.3-0.10.40.42.6-0.0-0.40.0
Bone surface0.30.72.2-0.20.6-0.20.80.1-1.3-0.5-0.71.00.71.01.5
Bone volume0.40.93.4-0.50.5-0.10.8-0.1-1.5-0.5-0.81.00.71.31.9
Breakpoint value in progressive ratio session0.20.42.7-0.1-0.20.5-0.20.50.20.20.20.9-1.6-0.3-0.2
Number of licking bursts0.20.72.0-0.60.5-0.10.7-0.7-1.1-1.1-1.00.4-0.41.21.4
Context. condit. distance diff. score0.70.93.11.80.10.1-0.20.41.00.70.4-0.7-1.1-1.1-1.6
Locomotion velocity, session 10.60.71.10.70.9-1.00.9-0.7-1.0-0.4-0.70.40.90.81.0
Locomotion distance, session 12.12.64.71.71.9-2.21.9-1.9-1.9-1.4-1.50.60.61.51.6
Locomotion velocity, session 20.00.00.30.30.1-0.10.10.10.0-0.0-0.00.5-0.1-0.2-0.2
Locomotion distance, session 20.50.82.20.10.6-1.00.7-1.0-1.0-0.7-0.71.50.70.71.0
Locomotion velocity, session 30.40.40.8-0.1-0.60.9-0.60.60.70.40.50.6-0.9-0.8-0.8
Locomotion distance, session 30.10.10.30.40.3-0.20.4-0.5-0.3-0.6-0.50.4-0.30.20.1
Stereotopy head waving bouts, day 32.53.04.4-1.6-2.01.7-2.02.11.82.12.10.6-1.0-1.8-1.5
Stereotopy head waving duration, day 30.40.51.2-0.3-0.60.3-0.71.00.61.11.10.20.3-0.7-0.5
Locomotion velocity, session 72.12.34.20.91.6-1.21.7-1.3-1.8-1.6-1.7-0.22.01.71.6
Locomotion distance, session 71.31.73.20.81.2-1.21.2-1.6-1.1-1.6-1.8-0.61.81.30.9
Stereotopy head waving bouts, day 71.01.22.5-0.8-1.01.2-1.01.20.71.21.21.4-1.6-0.9-0.4
Stereotopy head waving duration, day 71.31.62.9-0.6-1.11.2-1.11.40.91.51.71.6-1.6-1.2-0.7
Locomotion velocity, session 82.53.011.33.42.2-2.41.9-1.7-1.0-1.3-1.5-0.91.10.70.1
Locomotion distance, session 80.40.62.71.70.9-1.00.8-0.8-0.5-0.4-0.60.7-0.50.10.1
Degree of sensitization distance1.51.74.31.21.2-1.51.2-1.3-0.9-1.3-1.4-1.32.11.00.5
Degree of sensitization stereotypy1.01.22.9-0.8-1.01.2-0.91.00.61.11.11.6-1.7-0.8-0.4
Conditioned locomotion0.50.61.0-0.5-0.80.7-0.80.90.81.00.80.5-0.6-0.8-0.6
Cocaine response after cond. corrected0.50.85.6-0.9-0.70.0-0.60.40.10.70.92.4-0.0-0.50.1
Cocaine response after cond. not corrected0.50.85.6-0.9-0.70.0-0.50.4-0.00.70.82.40.7-0.30.3
Cocaine response before conditioning0.10.21.30.1-0.00.3-0.00.30.0-0.0-0.2-0.51.10.1-0.1
Saline control response0.30.31.11.00.6-0.60.6-0.3-0.5-0.5-0.51.10.30.20.1
Bone: connectivity density1.52.45.1-2.3-1.82.1-1.61.90.91.51.11.5-1.6-0.8-0.3
Bone: cortical apparent density3.04.77.6-2.4-2.72.8-2.72.32.52.02.1-0.9-1.3-1.9-1.8
Bone: cortical area0.10.10.4-0.3-0.10.6-0.00.4-0.20.1-0.10.20.40.20.3
Bone: cortical porosity0.30.41.4-0.6-0.30.3-0.20.4-0.30.70.51.2-1.00.10.6
Bone: cortical porosity0.30.32.1-0.20.0-0.00.10.2-0.50.50.31.4-0.70.10.6
Bone: cortical thickness1.42.33.6-1.1-1.71.9-1.71.81.61.61.50.8-1.3-1.5-1.4
Bone: cortical thickness6.58.09.9-2.2-3.12.9-3.13.12.73.03.02.5-2.8-2.9-2.3
Bone: cortical tissue density2.94.67.3-2.4-2.62.7-2.72.32.41.92.1-0.9-1.3-1.9-1.8
Condit. Reinf. active minus inactive responses2.02.23.6-1.2-1.71.5-1.70.91.81.31.60.5-1.9-1.6-1.6
Condit. Reinf. active-inactive response ratio2.52.75.1-1.2-1.81.9-1.81.22.01.31.60.3-2.3-1.8-1.8
Condit. Reinf. active responses1.41.83.0-1.2-1.51.3-1.50.91.61.21.30.4-1.7-1.4-1.4
Condit. Reinf. inactive responses0.00.00.1-0.3-0.10.0-0.10.1-0.00.10.10.4-0.00.00.1
Incentive salience index mean1.51.93.0-1.7-1.71.7-1.70.71.51.01.10.8-1.5-1.3-1.3
Condit. Reinf. lever presses0.30.51.8-1.3-0.91.1-0.70.20.40.1-0.00.8-0.3-0.2-0.2
Condit. Reinf. active minus inactive responses0.20.31.7-1.3-0.60.8-0.40.30.0-0.0-0.10.50.00.20.4
Condit. Reinf. active-inactive response ratio0.20.31.4-1.2-0.60.5-0.40.0-0.0-0.2-0.20.80.10.10.3
Condit. Reinf. active responses0.40.53.0-1.7-0.81.0-0.50.5-0.10.10.10.7-0.00.30.7
Condit. Reinf. inactive responses0.30.52.2-1.5-0.80.9-0.60.70.00.50.50.6-0.10.10.5
Condit. Reinf. lever presses0.20.31.5-0.5-0.50.5-0.40.50.40.30.30.2-1.2-0.3-0.3
Condit. Reinf. lever reinforcers received0.50.73.3-1.8-1.01.2-0.80.70.20.40.40.7-0.5-0.10.3
Conditioned reinforcement - actives0.00.10.3-0.3-0.00.1-0.0-0.60.1-0.4-0.5-0.5-0.00.2-0.1
Conditioned reinforcement - inactives0.10.31.9-0.4-0.10.1-0.1-0.50.2-0.3-0.3-1.40.70.1-0.2
Conditioned locomotion0.10.20.9-1.0-0.3-0.0-0.1-0.5-0.2-0.5-0.50.0-0.40.40.4
Patch foraging indifference point 0 sec0.41.03.4-1.5-1.41.8-1.20.81.10.10.0-0.40.6-0.6-0.8
Patch foraging indifference point AUC0.10.21.20.20.00.20.00.7-0.10.20.20.7-1.1-0.10.1
Delay disc. indifference point, 0s delay0.91.12.5-1.2-1.21.6-1.10.90.80.80.80.8-1.2-0.7-0.5
Delay disc. indifference point, 16s delay3.24.57.6-0.0-1.81.2-2.11.82.52.42.41.5-2.7-2.8-2.7
Delay disc. indifference point, 2s delay0.20.20.8-0.9-0.50.5-0.40.0-0.10.20.20.8-0.50.10.4
Delay disc. indifference point, 24s delay0.20.31.20.5-0.2-0.2-0.3-0.20.70.10.10.4-0.5-0.8-1.1
Delay disc. indifference point, 4s delay2.42.64.3-1.1-1.71.5-1.71.41.41.71.92.1-1.8-1.7-1.3
Delay disc. indifference point, 8s delay0.00.00.1-0.3-0.30.3-0.2-0.00.20.00.10.2-0.0-0.1-0.2
Indifference point function ln k0.10.41.00.1-0.50.4-0.60.40.80.60.5-0.30.9-0.8-1.0
Indifference point function log k0.10.41.00.1-0.50.4-0.60.40.80.60.5-0.30.9-0.8-1.0
Patch foraging total patch changes 0 sec0.20.61.9-1.2-0.91.4-0.80.50.7-0.3-0.4-0.60.8-0.2-0.5
Patch foraging total patch changes 12 sec1.11.56.0-2.4-1.52.1-1.21.40.30.40.41.0-0.9-0.10.4
Patch foraging total patch changes 18 sec0.10.31.0-0.6-0.01.00.10.4-0.3-0.8-0.8-0.6-0.00.60.5
Patch foraging total patch changes 24 sec0.20.82.3-1.1-1.01.5-0.91.20.50.60.61.0-1.1-0.5-0.2
Patch foraging total patch changes 6 sec0.50.93.0-1.4-1.21.7-1.11.00.80.30.10.5-0.2-0.6-0.6
Patch foraging time to switch 0 sec0.00.11.0-0.4-0.2-0.0-0.2-0.10.00.10.20.7-1.0-0.10.1
Patch foraging water rate 0 sec0.00.10.4-0.5-0.30.4-0.30.20.30.00.1-0.40.6-0.1-0.2
Patch foraging water rate 12 sec0.00.00.2-0.1-0.10.5-0.10.20.00.20.0-0.10.3-0.10.0
Patch foraging water rate 18 sec0.30.73.4-1.0-0.81.1-0.61.00.10.50.61.90.1-0.30.1
Patch foraging water rate 24 sec0.10.10.7-0.9-0.50.6-0.40.30.20.20.00.1-0.1-0.00.0
Patch foraging water rate 6 sec1.11.73.1-1.8-1.61.7-1.51.41.11.11.11.2-1.1-1.0-0.7
Seeking ratio, delayed vs. immediate footshock0.81.23.00.1-0.80.8-1.10.71.60.90.9-1.0-1.0-1.4-1.7
Distance traveled before self-admin0.20.53.0-0.4-0.60.2-0.50.80.40.60.71.7-0.4-0.6-0.3
Distance traveled after self-admin0.10.10.40.60.4-0.60.30.1-0.1-0.10.20.5-0.2-0.1-0.1
Extensor digitorum longus weight4.618.437.66.15.5-5.25.0-4.6-3.5-4.4-4.2-3.42.73.11.7
Bone: elastic displacement0.40.51.80.10.5-0.50.5-1.0-0.4-0.9-0.8-1.40.60.70.4
Bone: elastic work0.10.10.5-0.3-0.20.2-0.10.1-0.10.40.30.7-0.7-0.00.3
Bone: endosteal estimation2.76.710.02.02.9-2.63.0-2.4-3.2-2.4-2.6-0.22.82.82.9
Bone: endosteal perimeter1.94.66.11.52.4-1.92.5-2.0-2.5-2.3-2.3-1.32.12.42.3
Epididymis fat weight0.10.41.30.50.6-0.70.6-0.5-0.8-0.5-0.41.20.40.50.6
Delta time in closed arm before/after self-admin1.71.65.02.21.8-1.51.6-0.7-1.2-0.8-0.9-0.50.70.80.8
Delta time in open arm before/after self-admin0.30.30.80.0-0.40.1-0.60.40.70.80.9-0.1-0.5-0.8-0.8
Diff in mean of infusions in LGA sessions0.00.10.4-0.2-0.10.4-0.10.2-0.10.00.20.5-0.60.10.2
Delay discount exponential model param1.11.52.40.21.2-0.71.2-0.7-1.4-1.3-1.3-1.41.51.51.5
Extinction: sum of active levers before priming0.60.91.81.31.3-1.01.2-0.5-1.1-0.8-1.00.20.60.80.7
Active lever presses in extinction session 61.71.713.8-0.7-0.60.5-0.41.1-0.31.20.93.7-1.3-0.40.6
Bone: final force0.40.63.5-0.9-0.20.60.00.5-0.70.1-0.01.91.00.41.0
Bone: final moment0.30.62.9-0.7-0.10.40.20.3-0.80.1-0.11.71.10.51.0
Food consumed during 24 hour testing period0.30.61.01.01.0-1.00.9-0.9-0.7-1.0-0.6-0.3-0.20.60.4
Glucose0.30.51.90.30.7-0.30.80.0-1.2-0.3-0.30.30.71.01.4
Heart weight2.13.36.02.42.2-2.32.2-1.7-1.7-1.8-1.7-1.01.81.51.0
Delay discount hyperbolic model param0.91.21.90.31.0-0.61.1-0.5-1.2-1.1-1.2-1.31.41.41.3
Intermittent access intake day 1-15 change0.10.51.2-0.4-0.40.7-0.51.00.21.11.0-0.3-1.0-0.30.2
Intermittent access intake escalation0.10.41.1-0.3-0.30.6-0.41.00.21.10.9-0.5-0.9-0.30.2
Intermittent access intake escalation 20.20.30.90.40.6-0.50.6-0.1-0.7-0.1-0.1-0.9-0.00.70.9
Intermitt. access day 1 inactive lever presses0.33.95.8-1.5-2.12.0-2.22.41.82.32.41.7-1.6-2.0-1.5
Intermitt. access day 15 inactive lever presses0.31.53.0-1.7-1.51.5-1.50.71.41.11.1-0.9-0.4-0.9-1.0
Intermitt. access escalation Index0.20.52.11.40.7-0.70.60.5-0.50.30.41.3-0.3-0.20.1
Intermittent access day 1 total infusions0.10.20.6-0.0-0.40.1-0.4-0.10.60.20.20.4-0.1-0.6-0.8
Intermittent access day 15 total infusions0.40.91.9-0.1-0.70.7-0.91.00.91.41.30.1-1.1-1.1-0.9
Intermittent access terminal intake (last 3 days)0.40.71.4-0.4-0.80.6-0.90.90.91.21.10.0-0.9-1.0-0.8
Intermittent access total infusions0.50.61.2-0.1-0.70.5-0.80.71.01.01.00.2-0.8-1.1-1.1
Intermittent access day 1 locomotion0.10.20.7-0.10.2-0.40.2-0.6-0.2-0.5-0.3-0.90.30.40.2
Intermittent access day 15 total locomotion0.10.30.7-0.50.2-0.50.3-0.7-0.5-0.5-0.4-0.70.20.70.8
Intermittent access total locomotion0.20.30.9-0.9-0.60.5-0.60.00.40.30.5-0.6-0.5-0.2-0.1
Intermittent access standard deviation0.31.62.2-1.5-1.51.4-1.51.41.21.41.4-0.3-1.3-1.0-0.8
Left kidney weight0.10.52.61.10.3-0.10.20.50.10.40.61.6-0.6-0.6-0.4
Right kidney weight0.10.65.8-0.0-0.2-0.1-0.10.6-0.30.50.72.40.2-0.20.4
Cocaine induced anxiety0.30.83.11.80.9-1.20.8-0.7-0.4-0.3-0.31.70.1-0.2-0.3
Post-drug Anxiety0.30.41.30.8-0.00.0-0.2-0.40.60.20.21.1-0.2-0.9-1.1
Baseline Anxiety0.30.52.1-1.4-0.81.1-0.70.10.60.10.1-1.20.2-0.1-0.2
Tail length0.10.31.51.20.5-1.00.3-0.50.1-0.1-0.00.8-0.2-0.4-0.6
Length with tail0.73.37.52.72.3-2.52.2-1.8-1.7-1.5-1.51.01.61.10.9
Length without tail1.26.59.12.83.0-2.73.0-2.3-2.7-2.7-2.7-0.22.92.32.0
Times rat made contact with spout0.20.20.8-0.9-0.10.20.0-0.4-0.3-0.5-0.3-0.50.70.60.6
Lifetime Intake1.01.22.0-0.3-1.00.9-1.21.11.31.21.30.5-0.8-1.4-1.4
Liver weight, left0.40.81.30.50.8-0.80.9-0.7-1.0-1.1-1.00.81.20.80.7
Liver weight, right1.72.95.8-0.4-1.51.0-1.61.71.42.32.32.4-1.4-2.0-1.4
Locomotor activity0.30.52.7-1.0-0.40.4-0.10.1-0.5-0.00.21.6-0.80.30.9
Locomotor testing distance0.61.53.7-1.9-1.51.7-1.31.10.81.01.01.3-1.4-0.7-0.2
Locomotor testing rearing1.76.310.9-2.9-3.13.3-3.02.62.42.42.41.2-2.1-2.2-1.7
Locomotion in novel chamber3.14.26.3-2.3-2.52.0-2.42.02.01.91.92.1-1.5-1.9-1.6
Locomotion in novel chamber post-restriction0.10.30.9-0.9-0.1-0.10.1-0.6-0.5-0.2-0.30.30.50.60.9
Fecal boli incidents, locomotor time 10.61.73.40.51.2-1.21.2-1.7-1.1-1.2-1.2-1.81.61.41.1
Change in fecal boli incidents, locomotor task0.40.41.8-0.0-0.50.3-0.40.50.30.30.71.2-1.3-0.6-0.3
Time >=10cm from walls, locomotor time 10.20.31.0-0.3-0.51.0-0.60.40.70.30.2-0.4-0.0-0.5-0.7
Bouts of movement, locomotor time 10.10.10.30.30.4-0.50.4-0.1-0.4-0.0-0.00.50.60.20.3
Total resting periods, locomotor time 10.60.71.30.71.0-1.11.0-0.7-1.0-0.6-0.60.11.10.80.8
Rest time, locomotor task time 10.61.02.1-0.10.8-0.80.9-0.6-1.3-1.1-1.0-0.70.81.41.5
Distance moved, locomotor task time 10.51.42.70.2-0.90.6-1.00.81.41.31.31.4-1.2-1.6-1.6
Vertical activity count, locomotor time 10.00.10.30.60.2-0.50.2-0.10.00.1-0.10.1-0.2-0.1-0.2
Time >=10cm from walls, locomotor time 20.10.41.4-1.1-0.61.2-0.40.4-0.10.10.10.7-0.90.20.5
Bouts of movement, locomotor time 20.30.92.4-0.9-0.91.6-0.91.50.70.60.50.9-0.9-0.7-0.6
Total resting periods, locomotor time 20.20.92.2-0.7-0.91.5-0.91.40.80.60.60.9-0.7-0.8-0.8
Rest time, locomotor task time 20.50.81.60.81.0-0.91.0-0.7-0.9-0.9-0.8-0.51.30.90.8
Distance moved, locomotor task time 20.20.21.40.60.1-0.30.00.10.10.40.51.2-0.7-0.5-0.3
Vertical activity count, locomotor time 20.10.20.60.70.4-0.80.4-0.4-0.1-0.1-0.2-0.2-0.2-0.0-0.2
Light reinforcement 10.52.45.3-2.2-2.02.3-1.81.71.21.11.31.3-1.1-1.0-0.6
Light reinforcement 20.30.63.5-0.5-0.6-0.0-0.50.20.10.50.71.9-1.3-0.40.1
Bone: marrow area2.56.29.22.02.8-2.52.9-2.3-3.0-2.3-2.5-0.22.72.72.7
Bone: maximum diameter0.10.20.6-0.30.20.20.3-0.0-0.6-0.3-0.30.50.70.60.8
Bone: maximum force0.30.61.50.20.6-0.20.80.0-1.2-0.4-0.61.01.20.81.2
Bone: maximum moment0.40.71.90.40.8-0.30.9-0.2-1.2-0.5-0.70.81.40.91.2
Mean time between licks in bursts0.84.96.81.42.4-1.72.4-2.2-2.3-2.6-2.5-2.11.82.52.1
Mean num. licks in bursts0.20.61.3-0.1-0.70.3-0.80.51.11.00.9-0.60.8-0.9-1.2
Cd content in liver1.21.32.61.31.3-1.61.1-1.5-0.7-0.9-0.9-1.41.30.80.3
Co content in liver0.91.13.41.61.0-1.20.8-1.1-0.1-0.6-0.5-1.81.20.2-0.5
Cu content in liver0.81.02.2-0.3-0.91.0-1.00.81.41.20.9-0.00.1-1.2-1.5
Fe content in liver0.81.02.21.51.2-1.51.1-1.2-0.9-1.0-0.71.20.30.50.4
K content in liver3.53.56.0-1.1-1.72.0-1.82.41.52.52.21.6-2.0-1.7-1.1
Mg content in liver3.74.18.1-0.8-1.92.1-2.12.62.22.82.30.3-1.6-2.2-2.0
Mn content in liver1.61.82.9-1.2-1.41.7-1.41.71.31.61.3-0.2-1.6-1.1-0.8
Na content in liver0.60.62.7-0.7-0.20.4-0.10.9-0.71.00.61.6-0.30.31.1
Rb content in liver0.70.81.4-1.1-1.21.1-1.10.91.20.60.5-0.20.1-0.8-1.0
Se content in liver7.48.712.2-3.1-3.53.3-3.43.52.93.23.21.8-2.1-2.8-2.1
Sr content in liver0.30.31.20.2-0.30.6-0.40.40.60.20.2-1.1-0.1-0.4-0.7
Zn content in liver4.24.96.6-2.1-2.52.4-2.62.22.42.52.61.3-1.4-2.3-2.0
Bone: minimum diameter0.51.01.90.91.3-0.81.3-0.6-1.4-0.7-0.9-0.01.11.11.3
Time in familiar zone, hab. session 10.50.53.2-0.20.2-0.60.4-0.2-0.80.2-0.01.8-0.30.51.1
Time in novel zone, hab. session 11.01.14.5-0.6-0.91.3-1.00.81.30.50.5-2.10.4-0.7-1.2
Total zone transitions, hab. session 10.50.83.11.80.9-1.50.7-1.2-0.1-0.5-0.5-0.10.2-0.1-0.5
Total locomotion distance, hab. session 10.40.51.30.2-0.6-0.0-0.70.21.00.70.90.2-0.9-1.0-1.1
Locomotion velocity, hab. session 10.30.40.80.6-0.2-0.4-0.4-0.00.60.60.70.6-0.9-0.8-0.9
Time in familiar zone, hab. session 21.11.33.2-0.7-0.90.6-0.91.20.71.31.31.8-1.7-1.0-0.4
Time in novel zone, hab. session 20.50.53.1-0.5-0.10.5-0.0-0.3-0.0-0.5-0.5-1.31.80.40.1
Total zone transitions, hab. session 21.11.42.91.41.3-1.61.3-1.7-1.0-1.0-1.3-0.51.00.90.7
Total locomotion distance, hab. session 20.60.71.70.60.9-1.30.9-1.3-0.8-0.8-0.8-0.40.60.80.7
Locomotion velocity, hab. session 20.60.92.00.81.0-1.41.0-1.3-0.9-0.8-0.9-0.40.60.80.7
Novel to familiar place preference ratio0.30.30.90.8-0.10.1-0.20.20.60.50.60.5-0.7-0.8-0.9
Novelty place preference0.30.41.30.7-0.20.2-0.40.30.80.60.60.3-0.6-1.0-1.2
Time in novel zone, NPP test0.50.61.40.3-0.50.5-0.60.60.90.90.90.5-0.7-1.1-1.2
Total zone transitions, NPP test1.72.54.91.11.6-1.81.7-2.2-1.7-1.8-1.90.21.21.61.5
Total locomotion distance, NPP test0.70.92.10.40.8-1.30.9-1.4-1.1-1.1-1.10.10.51.01.0
Locomotion velocity, NPP test1.01.43.21.01.2-1.71.2-1.8-1.2-1.3-1.3-0.20.51.10.9
Intraocular pressure1.93.17.72.21.9-2.81.7-2.7-0.7-2.0-1.7-1.30.80.8-0.1
Delta distance traveled before/after self-admin0.40.41.51.20.9-1.00.7-0.5-0.3-0.3-0.2-0.9-0.10.2-0.1
Delta ambulatory time before/after self-admin0.50.92.01.31.3-1.41.2-0.8-0.9-0.7-0.6-0.50.20.70.7
Parametrial fat weight0.20.53.0-1.3-0.70.4-0.5-0.1-0.10.30.61.70.1-0.00.5
Pavlov. Cond. lever latency0.70.84.71.71.0-0.70.7-0.2-0.1-0.2-0.2-2.20.60.1-0.2
Pavlov. Cond. magazine entry latency4.05.212.9-3.6-2.92.8-2.52.21.52.12.12.3-1.7-1.4-0.5
Pavlov. Cond. change in total contacts7.37.811.7-3.1-3.43.3-3.32.62.92.62.61.8-2.5-2.7-2.4
Pavlov. Cond. index score2.63.310.5-3.2-2.42.2-2.01.41.11.41.32.2-1.2-0.9-0.3
Pavlov. Cond. latency score1.82.48.0-2.8-2.01.8-1.61.20.81.11.12.2-0.9-0.7-0.1
Pavlov. Cond. lever contacts0.80.94.0-2.0-1.10.8-0.80.20.10.10.12.0-0.6-0.10.3
Pavlov. Cond. magazine entry number5.77.315.03.93.4-3.33.1-2.5-2.3-2.5-2.5-2.22.22.01.3
Pavlov. Cond. intertrial magazine entries0.40.51.41.20.8-0.90.6-0.8-0.2-0.6-0.5-1.20.50.2-0.2
Pavlov. Cond. lever-magazine prob. diff.3.24.012.3-3.5-2.62.4-2.31.71.41.61.52.2-1.5-1.1-0.5
Pavlov. Cond. response bias4.96.112.4-3.5-3.13.0-2.82.22.02.12.12.6-2.3-1.8-1.2
Pavlov. Cond. lever latency0.10.21.01.00.4-0.40.3-0.30.10.0-0.1-0.30.6-0.2-0.4
Pavlov. Cond. magazine entry latency0.10.20.50.10.3-0.60.3-0.5-0.4-0.5-0.2-0.20.70.40.4
Pavlov. Cond. change in total contacts0.10.21.2-1.0-0.40.4-0.30.30.1-0.1-0.1-1.10.10.30.3
Pavlov. Cond. index score0.10.20.5-0.50.1-0.30.2-0.3-0.5-0.5-0.3-0.30.10.60.7
Pavlov. Cond. latency score0.10.20.6-0.40.2-0.40.3-0.4-0.6-0.6-0.3-0.40.20.70.8
Pavlov. Cond. lever contacts0.10.20.9-1.0-0.30.2-0.10.1-0.3-0.1-0.00.4-0.50.30.6
Pavlov. Cond. magazine entry number0.00.00.10.30.10.10.1-0.10.10.1-0.30.0-0.3-0.1-0.3
Pavlov. Cond. intertrial magazine entries0.20.42.01.40.4-0.30.2-0.40.5-0.2-0.5-0.60.0-0.5-1.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.30.2-0.40.3-0.4-0.5-0.6-0.2-0.30.20.60.7
Pavlov. Cond. response bias0.20.31.7-1.3-0.70.6-0.50.40.00.20.40.6-0.30.00.4
Time in closed arm before self-admin0.91.52.3-1.3-1.51.3-1.51.11.41.21.00.0-1.4-1.2-1.1
Time in closed arm after self-admin0.60.62.70.5-0.20.6-0.41.10.70.80.5-0.6-1.6-0.8-0.8
Time in open arm before self-admin0.60.81.21.11.0-0.71.1-0.5-1.1-0.7-0.70.51.10.80.9
Time in open arm after self-admin0.10.10.80.50.4-0.40.3-0.4-0.2-0.2-0.0-0.30.90.20.1
Bone: periosteal estimation0.71.73.20.61.4-0.91.5-0.9-1.8-1.0-1.20.31.71.51.8
Bone: periosteal perimeter1.42.74.51.01.8-1.31.9-1.5-2.1-1.7-1.6-0.21.51.92.0
Bone: post-yield work0.81.32.41.41.3-1.01.3-0.9-1.1-1.2-1.4-0.21.61.00.7
Progressive ratio test 1 active lever presses0.20.30.5-0.2-0.50.4-0.60.50.60.70.70.6-0.2-0.7-0.6
Progressive ratio test 1 breakpoint0.10.20.4-0.1-0.40.3-0.40.40.50.50.60.4-0.2-0.6-0.5
Progressive ratio test 1 inactive lever presses0.41.01.5-0.5-1.11.1-1.11.01.11.11.10.8-0.1-1.2-1.2
Progressive ratio test 2 active lever presses0.30.41.2-1.1-0.90.9-0.90.30.70.50.40.1-0.2-0.5-0.5
Progressive ratio test 2 breakpoint0.30.41.2-1.1-0.90.9-0.90.30.70.50.50.1-0.3-0.5-0.4
Progressive ratio test 2 inactive lever presses0.00.10.2-0.4-0.40.2-0.4-0.20.40.20.2-0.40.1-0.2-0.3
Incentive Sensitization - Responses0.10.31.9-1.4-0.60.4-0.4-0.50.1-0.3-0.4-0.60.50.40.2
Incentive Sensitization - Breakpoint0.10.31.7-1.3-0.60.4-0.4-0.50.1-0.3-0.3-0.50.40.30.3
Sum of active levers in priming session hrs 5-60.90.92.7-0.0-0.40.6-0.41.30.21.01.11.6-1.6-0.6-0.1
Progressive ratio0.10.21.3-0.5-0.30.3-0.20.5-0.10.30.31.1-0.4-0.10.2
Food seeking constrained by brief footshock0.30.41.8-0.7-0.60.2-0.40.80.00.50.51.3-0.8-0.20.2
Seeking ratio, punishment vs. effort0.00.00.20.20.1-0.20.0-0.00.10.00.1-0.5-0.2-0.1-0.2
Retroperitoneal fat weight0.00.20.9-0.3-0.40.2-0.3-0.00.20.10.30.9-0.7-0.3-0.2
Reaction time number correct0.31.22.11.11.3-0.61.3-0.6-1.3-1.4-1.5-0.31.11.21.1
Reaction time mean minus median0.21.34.00.61.1-1.21.0-1.1-0.8-1.3-1.1-2.01.11.10.7
Reaction time mean minus median AUC0.10.52.20.10.5-0.60.5-0.5-0.4-0.9-0.6-1.50.60.70.4
Reaction time num false alarms0.30.51.9-0.70.20.10.4-0.1-1.0-0.7-0.70.5-0.31.01.4
Reaction time num false alarms AUC0.40.93.1-0.60.5-0.10.7-0.5-1.3-1.2-1.10.20.21.41.8
Reaction time trials correct on left0.31.22.11.11.3-0.61.3-0.6-1.3-1.4-1.5-0.31.11.21.1
Reaction time trials on left0.41.22.11.11.3-0.61.3-0.6-1.3-1.4-1.5-0.41.11.21.1
Reaction time mean0.51.01.7-0.6-1.00.7-1.11.11.21.11.1-0.6-1.3-1.0-1.1
Reaction time mean AUC0.61.32.4-0.6-1.10.9-1.21.31.31.31.3-0.4-1.6-1.2-1.2
Median of all reaction times1.72.73.8-1.2-1.81.4-1.81.81.81.91.80.1-2.0-1.7-1.5
Reaction time omissions0.20.30.5-0.6-0.70.6-0.70.70.60.50.50.0-0.5-0.4-0.4
Reaction time false alarm rate0.20.31.2-1.1-0.30.3-0.00.0-0.5-0.3-0.20.3-0.40.61.0
Reaction time premature initiation rate2.03.15.7-0.9-1.61.2-1.71.91.52.22.22.4-1.8-1.9-1.3
Reaction time premature initiations0.30.82.80.0-0.60.5-0.61.20.51.11.11.7-0.9-1.0-0.5
Std. dev. reaction times0.10.32.2-0.10.3-0.50.3-0.2-0.2-0.3-0.3-1.50.30.50.3
Reaction time trials completed0.41.22.11.11.3-0.61.3-0.6-1.3-1.4-1.5-0.41.11.21.1
Reaction time trials AUC0.41.32.31.01.3-0.61.3-0.7-1.3-1.4-1.5-0.61.11.21.1
Run reversals in cocaine runway, females1.11.34.51.4-0.30.3-0.60.81.41.01.00.5-0.7-1.7-2.1
Run reversals in cocaine runway, males0.30.30.6-0.3-0.60.3-0.70.10.80.60.70.40.4-0.7-0.8
Latency to leave start box in cocaine runway0.60.81.91.41.1-0.91.0-0.4-0.7-0.9-0.9-1.20.50.70.4
Latency to leave start box in cocaine runway, F0.40.52.41.51.0-0.90.8-0.2-0.4-0.5-0.5-0.30.30.2-0.1
Latency to leave start box in cocaine runway, M0.10.11.0-0.1-0.00.30.00.0-0.0-0.3-0.3-1.0-0.10.20.2
Std. dev. time between licks in bursts0.51.02.20.01.0-0.51.1-0.7-1.3-1.3-1.2-0.60.11.41.5
Total sessions with >9 infusions1.21.52.7-0.3-1.11.1-1.31.31.51.31.30.1-1.2-1.6-1.6
Short access day 1 total inactive lever presses0.81.72.7-1.3-1.61.2-1.61.31.51.31.40.3-0.2-1.4-1.4
Short access day 10 total inactive lever presses0.00.10.2-0.3-0.20.1-0.2-0.20.3-0.3-0.3-0.40.4-0.1-0.4
Short access day 1 total infusions1.93.86.1-0.4-1.71.7-2.02.22.22.22.31.3-1.5-2.5-2.3
Short access day 10 total infusions0.40.71.0-0.6-0.90.7-0.90.90.90.91.00.5-0.6-0.9-0.8
Short access total infusions1.62.33.4-0.6-1.41.3-1.61.71.61.71.81.2-1.1-1.9-1.7
Short access day 1 locomotion1.52.53.5-0.9-1.61.4-1.71.71.61.61.61.3-1.9-1.8-1.5
Short access day 10 total locomotion0.10.41.7-1.3-0.30.1-0.1-0.3-0.4-0.2-0.1-1.1-0.20.81.0
Short access total locomotion0.10.10.4-0.4-0.30.1-0.20.30.20.00.1-0.5-0.6-0.0-0.1
One hour access (0.3 mA shock)0.10.10.40.30.3-0.10.2-0.2-0.0-0.1-0.1-0.60.30.0-0.1
Compulsive drug intake0.50.73.30.3-0.21.0-0.40.41.00.10.2-1.80.2-0.8-1.4
One hour access (shock baseline)0.10.20.9-0.1-0.30.1-0.30.40.20.70.71.0-0.5-0.4-0.2
Social response proportion0.10.20.80.90.2-0.60.2-0.20.10.10.00.8-0.1-0.3-0.4
Social responses0.20.22.10.00.1-0.40.2-0.4-0.3-0.20.01.4-0.00.10.3
Social time0.91.43.20.11.0-1.11.1-1.4-1.4-1.2-1.10.41.81.41.4
Soleus weight0.72.15.20.11.3-0.91.5-1.1-2.1-1.5-1.20.81.31.82.3
Bone: stiffness0.20.43.00.1-0.10.3-0.10.8-0.20.60.51.70.5-0.20.2
Tibialis anterior weight0.62.15.42.32.0-2.11.8-1.5-1.5-1.3-0.90.30.40.90.8
Time to tail flick, vehicle, before self-admin1.31.73.3-0.00.9-1.11.0-1.8-1.0-1.5-1.7-1.31.51.41.0
Time to tail flick, vehicle, after self-admin0.20.41.1-0.50.3-0.30.4-0.5-0.7-0.8-0.80.51.00.80.8
Time to tail flick, test, before self-admin0.40.41.20.90.8-1.10.7-0.7-0.6-0.8-0.60.30.20.40.3
Time to tail flick, test, after self-admin1.31.32.20.00.9-0.91.1-1.5-1.3-1.5-1.4-0.60.81.51.5
Delta time to tail flick, vehicle, before/after SA0.40.41.3-0.8-0.00.20.20.2-0.8-0.1-0.11.10.60.71.1
Delta time to tail flick, test, before/after SA0.20.31.4-1.2-0.70.8-0.50.00.20.0-0.0-0.20.20.10.1
Tibia length1.13.05.02.22.1-2.22.1-1.6-1.9-1.3-1.50.91.81.31.3
Ambulatory time before self-admin0.10.30.9-0.3-0.50.2-0.50.60.50.30.50.9-0.2-0.6-0.6
Ambulatory time after self-admin0.30.52.01.10.9-1.40.8-0.3-0.7-0.3-0.10.60.50.30.3
Bone: tissue strength2.02.13.71.21.6-0.91.6-1.3-1.3-1.8-1.9-1.61.51.51.0
Total heroin consumption0.91.03.8-1.8-0.91.1-0.60.8-0.30.20.41.9-1.00.31.0
Bone: trabecular number1.93.59.0-3.0-2.22.4-1.92.00.81.91.52.3-1.8-0.80.1
Bone: trabecular spacing1.42.14.31.61.6-2.11.6-2.1-1.3-1.3-1.10.21.31.10.9
Bone: trabecular thickness0.30.41.0-0.20.40.10.50.1-0.8-0.5-0.7-0.70.80.91.0
Bone: trabecular tissue density0.50.93.10.3-0.70.6-0.90.61.40.70.9-0.70.0-1.3-1.7
Water consumed over 24 hours0.61.12.00.41.0-0.91.1-1.1-1.2-1.4-1.2-0.90.41.31.2
Number of responses in last shaping day0.40.63.8-0.4-0.40.8-0.60.40.70.40.5-1.9-0.1-0.4-0.5