Hub : Genes

LOC108352132

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XR_010055452.1 0.04 0.03 6.1e-04 0.05 0.04 0.04 0.04 1.5e-05 1.9e-04 1.3e-04 8.4e-05
2 Brain isoform ratio XR_001840282.3 0.03 0.02 7.1e-03 0.01 0.01 0 0.01 2.1e-02 1.9e-02 1.2e-01 7.4e-02
3 Liver gene expression LOC108352132 0.03 0.02 2.7e-04 0.03 0.02 0.01 0.02 1.7e-04 1.3e-03 8.5e-03 8.9e-04
4 Brain intron excision ratio chr10_84822920_84823665 0.02 0.02 9.3e-03 0.01 0.02 0.01 0.01 5.2e-02 4.7e-03 1.5e-02 1.6e-02
5 Adipose gene expression LOC108352132 0.05 0.03 3.0e-06 0.05 0.04 0.05 0.04 3.6e-06 1.8e-05 4.1e-06 1.2e-05
6 Brain isoform ratio XR_010055454.1 0.05 0.03 2.3e-05 0.03 0.05 0.04 0.03 4.3e-04 2.2e-05 9.4e-05 5.6e-04
7 PL gene expression LOC108352132 0.02 0.01 6.4e-03 0.02 0.02 0 0.01 3.7e-03 4.1e-03 9.1e-02 1.8e-02
8 pVTA gene expression LOC108352132 0.06 0.04 2.8e-05 0.06 0.06 0.03 0.06 1.0e-05 1.7e-05 1.9e-03 2.2e-05
9 OFC gene expression LOC108352132 0.65 0.17 3.9e-07 0.21 0.29 0.23 0.03 1.1e-05 1.3e-07 2.9e-06 7.9e-02
10 Adipose alternative TSS XR_001840282.3 0.02 0.02 2.3e-03 0.03 0.01 0.02 0.02 1.7e-04 1.7e-02 2.4e-03 2.2e-03
11 Brain mRNA stability LOC108352132 0.02 0.01 1.0e-02 0.02 0.02 0.01 0.01 6.3e-03 3.2e-03 1.4e-02 1.8e-02
12 Brain isoform ratio XR_010055452.1 0.04 0.02 1.1e-04 0.01 0.04 0.04 0.03 1.5e-02 9.3e-05 2.2e-04 1.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.73.71.9-1.4-1.8-1.2-1.60.5-1.4-0.91.51.1-0.50.1
Area under the delay curve1.31.52.50.4-1.2-0.8-1.3-0.71.3-1.3-1.41.41.6-1.5-1.4
BMI with tail1.96.710.2-2.63.23.03.22.4-3.02.62.4-0.3-2.12.52.5
BMI without tail1.13.35.9-1.82.22.42.21.8-2.11.71.60.3-1.31.71.8
Body weight3.716.125.9-4.85.05.14.93.9-4.43.73.60.5-3.33.43.2
Weight adjusted by age0.40.66.8-0.1-0.2-0.2-0.1-0.3-0.1-0.4-0.42.60.0-0.40.0
Bone surface0.40.72.20.20.60.20.8-0.1-1.30.50.71.0-0.71.01.5
Bone volume0.50.93.40.50.50.10.80.1-1.50.50.81.0-0.71.31.9
Breakpoint value in progressive ratio session0.30.42.70.1-0.2-0.5-0.2-0.50.2-0.2-0.20.91.6-0.3-0.2
Number of licking bursts0.50.72.00.60.50.10.70.7-1.11.11.00.40.41.21.4
Context. condit. distance diff. score0.70.93.1-1.80.1-0.1-0.2-0.41.0-0.7-0.4-0.71.1-1.1-1.6
Locomotion velocity, session 10.60.71.1-0.70.91.00.90.7-1.00.40.70.4-0.90.81.0
Locomotion distance, session 12.12.64.7-1.71.92.21.91.9-1.91.41.50.6-0.61.51.6
Locomotion velocity, session 20.00.00.3-0.30.10.10.1-0.10.00.00.00.50.1-0.2-0.2
Locomotion distance, session 20.50.82.2-0.10.61.00.71.0-1.00.70.71.5-0.70.71.0
Locomotion velocity, session 30.40.40.80.1-0.6-0.9-0.6-0.60.7-0.4-0.50.60.9-0.8-0.8
Locomotion distance, session 30.10.10.3-0.40.30.20.40.5-0.30.60.50.40.30.20.1
Stereotopy head waving bouts, day 32.63.04.41.6-2.0-1.7-2.0-2.11.8-2.1-2.10.61.0-1.8-1.5
Stereotopy head waving duration, day 30.40.51.20.3-0.6-0.3-0.7-1.00.6-1.1-1.10.2-0.3-0.7-0.5
Locomotion velocity, session 72.12.34.2-0.91.61.21.71.3-1.81.61.7-0.2-2.01.71.6
Locomotion distance, session 71.41.73.2-0.81.21.21.21.6-1.11.61.8-0.6-1.81.30.9
Stereotopy head waving bouts, day 71.11.22.50.8-1.0-1.2-1.0-1.20.7-1.2-1.21.41.6-0.9-0.4
Stereotopy head waving duration, day 71.31.62.90.6-1.1-1.2-1.1-1.40.9-1.5-1.71.61.6-1.2-0.7
Locomotion velocity, session 82.53.011.3-3.42.22.41.91.7-1.01.31.5-0.9-1.10.70.1
Locomotion distance, session 80.40.62.7-1.70.91.00.80.8-0.50.40.60.70.50.10.1
Degree of sensitization distance1.61.74.3-1.21.21.51.21.3-0.91.31.4-1.3-2.11.00.5
Degree of sensitization stereotypy1.11.22.90.8-1.0-1.2-0.9-1.00.6-1.1-1.11.61.7-0.8-0.4
Conditioned locomotion0.50.61.00.5-0.8-0.7-0.8-0.90.8-1.0-0.80.50.6-0.8-0.6
Cocaine response after cond. corrected0.60.85.60.9-0.7-0.0-0.6-0.40.1-0.7-0.92.40.0-0.50.1
Cocaine response after cond. not corrected0.60.85.60.9-0.7-0.0-0.5-0.4-0.0-0.7-0.82.4-0.7-0.30.3
Cocaine response before conditioning0.10.21.3-0.1-0.0-0.3-0.0-0.30.00.00.2-0.5-1.10.1-0.1
Saline control response0.30.31.1-1.00.60.60.60.3-0.50.50.51.1-0.30.20.1
Bone: connectivity density1.62.45.12.3-1.8-2.1-1.6-1.90.9-1.5-1.11.51.6-0.8-0.3
Bone: cortical apparent density3.54.77.62.4-2.7-2.8-2.7-2.32.5-2.0-2.1-0.91.3-1.9-1.8
Bone: cortical area0.10.10.40.3-0.1-0.6-0.0-0.4-0.2-0.10.10.2-0.40.20.3
Bone: cortical porosity0.30.41.40.6-0.3-0.3-0.2-0.4-0.3-0.7-0.51.21.00.10.6
Bone: cortical porosity0.30.32.10.20.00.00.1-0.2-0.5-0.5-0.31.40.70.10.6
Bone: cortical thickness1.42.33.61.1-1.7-1.9-1.7-1.81.6-1.6-1.50.81.3-1.5-1.4
Bone: cortical thickness6.88.09.92.2-3.1-2.9-3.1-3.12.7-3.0-3.02.52.8-2.9-2.3
Bone: cortical tissue density3.44.67.32.4-2.6-2.7-2.7-2.32.4-1.9-2.1-0.91.3-1.9-1.8
Condit. Reinf. active minus inactive responses2.02.23.61.2-1.7-1.5-1.7-0.91.8-1.3-1.60.51.9-1.6-1.6
Condit. Reinf. active-inactive response ratio2.62.75.11.2-1.8-1.9-1.8-1.22.0-1.3-1.60.32.3-1.8-1.8
Condit. Reinf. active responses1.41.83.01.2-1.5-1.3-1.5-0.91.6-1.2-1.30.41.7-1.4-1.4
Condit. Reinf. inactive responses0.00.00.10.3-0.1-0.0-0.1-0.1-0.0-0.1-0.10.40.00.00.1
Incentive salience index mean1.51.93.01.7-1.7-1.7-1.7-0.71.5-1.0-1.10.81.5-1.3-1.3
Condit. Reinf. lever presses0.30.51.81.3-0.9-1.1-0.7-0.20.4-0.10.00.80.3-0.2-0.2
Condit. Reinf. active minus inactive responses0.20.31.71.3-0.6-0.8-0.4-0.30.00.00.10.5-0.00.20.4
Condit. Reinf. active-inactive response ratio0.20.31.41.2-0.6-0.5-0.4-0.0-0.00.20.20.8-0.10.10.3
Condit. Reinf. active responses0.40.53.01.7-0.8-1.0-0.5-0.5-0.1-0.1-0.10.70.00.30.7
Condit. Reinf. inactive responses0.40.52.21.5-0.8-0.9-0.6-0.70.0-0.5-0.50.60.10.10.5
Condit. Reinf. lever presses0.20.31.50.5-0.5-0.5-0.4-0.50.4-0.3-0.30.21.2-0.3-0.3
Condit. Reinf. lever reinforcers received0.50.73.31.8-1.0-1.2-0.8-0.70.2-0.4-0.40.70.5-0.10.3
Conditioned reinforcement - actives0.10.10.30.3-0.0-0.1-0.00.60.10.40.5-0.50.00.2-0.1
Conditioned reinforcement - inactives0.20.31.90.4-0.1-0.1-0.10.50.20.30.3-1.4-0.70.1-0.2
Conditioned locomotion0.20.20.91.0-0.30.0-0.10.5-0.20.50.50.00.40.40.4
Patch foraging indifference point 0 sec0.61.03.41.5-1.4-1.8-1.2-0.81.1-0.1-0.0-0.4-0.6-0.6-0.8
Patch foraging indifference point AUC0.10.21.2-0.20.0-0.20.0-0.7-0.1-0.2-0.20.71.1-0.10.1
Delay disc. indifference point, 0s delay1.01.12.51.2-1.2-1.6-1.1-0.90.8-0.8-0.80.81.2-0.7-0.5
Delay disc. indifference point, 16s delay4.14.57.60.0-1.8-1.2-2.1-1.82.5-2.4-2.41.52.7-2.8-2.7
Delay disc. indifference point, 2s delay0.20.20.80.9-0.5-0.5-0.4-0.0-0.1-0.2-0.20.80.50.10.4
Delay disc. indifference point, 24s delay0.20.31.2-0.5-0.20.2-0.30.20.7-0.1-0.10.40.5-0.8-1.1
Delay disc. indifference point, 4s delay2.52.64.31.1-1.7-1.5-1.7-1.41.4-1.7-1.92.11.8-1.7-1.3
Delay disc. indifference point, 8s delay0.00.00.10.3-0.3-0.3-0.20.00.2-0.0-0.10.20.0-0.1-0.2
Indifference point function ln k0.20.41.0-0.1-0.5-0.4-0.6-0.40.8-0.6-0.5-0.3-0.9-0.8-1.0
Indifference point function log k0.20.41.0-0.1-0.5-0.4-0.6-0.40.8-0.6-0.5-0.3-0.9-0.8-1.0
Patch foraging total patch changes 0 sec0.30.61.91.2-0.9-1.4-0.8-0.50.70.30.4-0.6-0.8-0.2-0.5
Patch foraging total patch changes 12 sec1.21.56.02.4-1.5-2.1-1.2-1.40.3-0.4-0.41.00.9-0.10.4
Patch foraging total patch changes 18 sec0.20.31.00.6-0.0-1.00.1-0.4-0.30.80.8-0.60.00.60.5
Patch foraging total patch changes 24 sec0.50.82.31.1-1.0-1.5-0.9-1.20.5-0.6-0.61.01.1-0.5-0.2
Patch foraging total patch changes 6 sec0.60.93.01.4-1.2-1.7-1.1-1.00.8-0.3-0.10.50.2-0.6-0.6
Patch foraging time to switch 0 sec0.10.11.00.4-0.20.0-0.20.10.0-0.1-0.20.71.0-0.10.1
Patch foraging water rate 0 sec0.10.10.40.5-0.3-0.4-0.3-0.20.3-0.0-0.1-0.4-0.6-0.1-0.2
Patch foraging water rate 12 sec0.00.00.20.1-0.1-0.5-0.1-0.20.0-0.2-0.0-0.1-0.3-0.10.0
Patch foraging water rate 18 sec0.50.73.41.0-0.8-1.1-0.6-1.00.1-0.5-0.61.9-0.1-0.30.1
Patch foraging water rate 24 sec0.10.10.70.9-0.5-0.6-0.4-0.30.2-0.2-0.00.10.1-0.00.0
Patch foraging water rate 6 sec1.21.73.11.8-1.6-1.7-1.5-1.41.1-1.1-1.11.21.1-1.0-0.7
Seeking ratio, delayed vs. immediate footshock1.01.23.0-0.1-0.8-0.8-1.1-0.71.6-0.9-0.9-1.01.0-1.4-1.7
Distance traveled before self-admin0.40.53.00.4-0.6-0.2-0.5-0.80.4-0.6-0.71.70.4-0.6-0.3
Distance traveled after self-admin0.10.10.4-0.60.40.60.3-0.1-0.10.1-0.20.50.2-0.1-0.1
Extensor digitorum longus weight4.718.437.6-6.15.55.25.04.6-3.54.44.2-3.4-2.73.11.7
Bone: elastic displacement0.50.51.8-0.10.50.50.51.0-0.40.90.8-1.4-0.60.70.4
Bone: elastic work0.10.10.50.3-0.2-0.2-0.1-0.1-0.1-0.4-0.30.70.7-0.00.3
Bone: endosteal estimation3.16.710.0-2.02.92.63.02.4-3.22.42.6-0.2-2.82.82.9
Bone: endosteal perimeter2.24.66.1-1.52.41.92.52.0-2.52.32.3-1.3-2.12.42.3
Epididymis fat weight0.10.41.3-0.50.60.70.60.5-0.80.50.41.2-0.40.50.6
Delta time in closed arm before/after self-admin1.71.65.0-2.21.81.51.60.7-1.20.80.9-0.5-0.70.80.8
Delta time in open arm before/after self-admin0.30.30.8-0.0-0.4-0.1-0.6-0.40.7-0.8-0.9-0.10.5-0.8-0.8
Diff in mean of infusions in LGA sessions0.10.10.40.2-0.1-0.4-0.1-0.2-0.1-0.0-0.20.50.60.10.2
Delay discount exponential model param1.31.52.4-0.21.20.71.20.7-1.41.31.3-1.4-1.51.51.5
Extinction: sum of active levers before priming0.80.91.8-1.31.31.01.20.5-1.10.81.00.2-0.60.80.7
Active lever presses in extinction session 61.81.713.80.7-0.6-0.5-0.4-1.1-0.3-1.2-0.93.71.3-0.40.6
Bone: final force0.40.63.50.9-0.2-0.60.0-0.5-0.7-0.10.01.9-1.00.41.0
Bone: final moment0.30.62.90.7-0.1-0.40.2-0.3-0.8-0.10.11.7-1.10.51.0
Food consumed during 24 hour testing period0.40.61.0-1.01.01.00.90.9-0.71.00.6-0.30.20.60.4
Glucose0.30.51.9-0.30.70.30.8-0.0-1.20.30.30.3-0.71.01.4
Heart weight2.23.36.0-2.42.22.32.21.7-1.71.81.7-1.0-1.81.51.0
Delay discount hyperbolic model param1.11.21.9-0.31.00.61.10.5-1.21.11.2-1.3-1.41.41.3
Intermittent access intake day 1-15 change0.20.51.20.4-0.4-0.7-0.5-1.00.2-1.1-1.0-0.31.0-0.30.2
Intermittent access intake escalation0.20.41.10.3-0.3-0.6-0.4-1.00.2-1.1-0.9-0.50.9-0.30.2
Intermittent access intake escalation 20.30.30.9-0.40.60.50.60.1-0.70.10.1-0.90.00.70.9
Intermitt. access day 1 inactive lever presses1.03.95.81.5-2.1-2.0-2.2-2.41.8-2.3-2.41.71.6-2.0-1.5
Intermitt. access day 15 inactive lever presses0.71.53.01.7-1.5-1.5-1.5-0.71.4-1.1-1.1-0.90.4-0.9-1.0
Intermitt. access escalation Index0.40.52.1-1.40.70.70.6-0.5-0.5-0.3-0.41.30.3-0.20.1
Intermittent access day 1 total infusions0.10.20.60.0-0.4-0.1-0.40.10.6-0.2-0.20.40.1-0.6-0.8
Intermittent access day 15 total infusions0.60.91.90.1-0.7-0.7-0.9-1.00.9-1.4-1.30.11.1-1.1-0.9
Intermittent access terminal intake (last 3 days)0.50.71.40.4-0.8-0.6-0.9-0.90.9-1.2-1.10.00.9-1.0-0.8
Intermittent access total infusions0.50.61.20.1-0.7-0.5-0.8-0.71.0-1.0-1.00.20.8-1.1-1.1
Intermittent access day 1 locomotion0.10.20.70.10.20.40.20.6-0.20.50.3-0.9-0.30.40.2
Intermittent access day 15 total locomotion0.20.30.70.50.20.50.30.7-0.50.50.4-0.7-0.20.70.8
Intermittent access total locomotion0.20.30.90.9-0.6-0.5-0.6-0.00.4-0.3-0.5-0.60.5-0.2-0.1
Intermittent access standard deviation0.81.62.21.5-1.5-1.4-1.5-1.41.2-1.4-1.4-0.31.3-1.0-0.8
Left kidney weight0.10.52.6-1.10.30.10.2-0.50.1-0.4-0.61.60.6-0.6-0.4
Right kidney weight0.10.65.80.0-0.20.1-0.1-0.6-0.3-0.5-0.72.4-0.2-0.20.4
Cocaine induced anxiety0.60.83.1-1.80.91.20.80.7-0.40.30.31.7-0.1-0.2-0.3
Post-drug Anxiety0.40.41.3-0.8-0.0-0.0-0.20.40.6-0.2-0.21.10.2-0.9-1.1
Baseline Anxiety0.50.52.11.4-0.8-1.1-0.7-0.10.6-0.1-0.1-1.2-0.2-0.1-0.2
Tail length0.10.31.5-1.20.51.00.30.50.10.10.00.80.2-0.4-0.6
Length with tail0.83.37.5-2.72.32.52.21.8-1.71.51.51.0-1.61.10.9
Length without tail2.06.59.1-2.83.02.73.02.3-2.72.72.7-0.2-2.92.32.0
Times rat made contact with spout0.20.20.80.9-0.1-0.20.00.4-0.30.50.3-0.5-0.70.60.6
Lifetime Intake1.01.22.00.3-1.0-0.9-1.2-1.11.3-1.2-1.30.50.8-1.4-1.4
Liver weight, left0.50.81.3-0.50.80.80.90.7-1.01.11.00.8-1.20.80.7
Liver weight, right1.72.95.80.4-1.5-1.0-1.6-1.71.4-2.3-2.32.41.4-2.0-1.4
Locomotor activity0.30.52.71.0-0.4-0.4-0.1-0.1-0.50.0-0.21.60.80.30.9
Locomotor testing distance0.91.53.71.9-1.5-1.7-1.3-1.10.8-1.0-1.01.31.4-0.7-0.2
Locomotor testing rearing3.16.310.92.9-3.1-3.3-3.0-2.62.4-2.4-2.41.22.1-2.2-1.7
Locomotion in novel chamber3.34.26.32.3-2.5-2.0-2.4-2.02.0-1.9-1.92.11.5-1.9-1.6
Locomotion in novel chamber post-restriction0.20.30.90.9-0.10.10.10.6-0.50.20.30.3-0.50.60.9
Fecal boli incidents, locomotor time 11.21.73.4-0.51.21.21.21.7-1.11.21.2-1.8-1.61.41.1
Change in fecal boli incidents, locomotor task0.40.41.80.0-0.5-0.3-0.4-0.50.3-0.3-0.71.21.3-0.6-0.3
Time >=10cm from walls, locomotor time 10.30.31.00.3-0.5-1.0-0.6-0.40.7-0.3-0.2-0.40.0-0.5-0.7
Bouts of movement, locomotor time 10.10.10.3-0.30.40.50.40.1-0.40.00.00.5-0.60.20.3
Total resting periods, locomotor time 10.60.71.3-0.71.01.11.00.7-1.00.60.60.1-1.10.80.8
Rest time, locomotor task time 10.81.02.10.10.80.80.90.6-1.31.11.0-0.7-0.81.41.5
Distance moved, locomotor task time 10.91.42.7-0.2-0.9-0.6-1.0-0.81.4-1.3-1.31.41.2-1.6-1.6
Vertical activity count, locomotor time 10.00.10.3-0.60.20.50.20.10.0-0.10.10.10.2-0.1-0.2
Time >=10cm from walls, locomotor time 20.30.41.41.1-0.6-1.2-0.4-0.4-0.1-0.1-0.10.70.90.20.5
Bouts of movement, locomotor time 20.60.92.40.9-0.9-1.6-0.9-1.50.7-0.6-0.50.90.9-0.7-0.6
Total resting periods, locomotor time 20.50.92.20.7-0.9-1.5-0.9-1.40.8-0.6-0.60.90.7-0.8-0.8
Rest time, locomotor task time 20.60.81.6-0.81.00.91.00.7-0.90.90.8-0.5-1.30.90.8
Distance moved, locomotor task time 20.20.21.4-0.60.10.30.0-0.10.1-0.4-0.51.20.7-0.5-0.3
Vertical activity count, locomotor time 20.10.20.6-0.70.40.80.40.4-0.10.10.2-0.20.2-0.0-0.2
Light reinforcement 11.02.45.32.2-2.0-2.3-1.8-1.71.2-1.1-1.31.31.1-1.0-0.6
Light reinforcement 20.40.63.50.5-0.60.0-0.5-0.20.1-0.5-0.71.91.3-0.40.1
Bone: marrow area2.96.29.2-2.02.82.52.92.3-3.02.32.5-0.2-2.72.72.7
Bone: maximum diameter0.10.20.60.30.2-0.20.30.0-0.60.30.30.5-0.70.60.8
Bone: maximum force0.40.61.5-0.20.60.20.8-0.0-1.20.40.61.0-1.20.81.2
Bone: maximum moment0.40.71.9-0.40.80.30.90.2-1.20.50.70.8-1.40.91.2
Mean time between licks in bursts2.04.96.8-1.42.41.72.42.2-2.32.62.5-2.1-1.82.52.1
Mean num. licks in bursts0.40.61.30.1-0.7-0.3-0.8-0.51.1-1.0-0.9-0.6-0.8-0.9-1.2
Cd content in liver1.21.32.6-1.31.31.61.11.5-0.70.90.9-1.4-1.30.80.3
Co content in liver0.91.13.4-1.61.01.20.81.1-0.10.60.5-1.8-1.20.2-0.5
Cu content in liver0.81.02.20.3-0.9-1.0-1.0-0.81.4-1.2-0.9-0.0-0.1-1.2-1.5
Fe content in liver0.91.02.2-1.51.21.51.11.2-0.91.00.71.2-0.30.50.4
K content in liver3.63.56.01.1-1.7-2.0-1.8-2.41.5-2.5-2.21.62.0-1.7-1.1
Mg content in liver4.04.18.10.8-1.9-2.1-2.1-2.62.2-2.8-2.30.31.6-2.2-2.0
Mn content in liver1.61.82.91.2-1.4-1.7-1.4-1.71.3-1.6-1.3-0.21.6-1.1-0.8
Na content in liver0.60.62.70.7-0.2-0.4-0.1-0.9-0.7-1.0-0.61.60.30.31.1
Rb content in liver0.70.81.41.1-1.2-1.1-1.1-0.91.2-0.6-0.5-0.2-0.1-0.8-1.0
Se content in liver7.48.712.23.1-3.5-3.3-3.4-3.52.9-3.2-3.21.82.1-2.8-2.1
Sr content in liver0.30.31.2-0.2-0.3-0.6-0.4-0.40.6-0.2-0.2-1.10.1-0.4-0.7
Zn content in liver4.44.96.62.1-2.5-2.4-2.6-2.22.4-2.5-2.61.31.4-2.3-2.0
Bone: minimum diameter0.61.01.9-0.91.30.81.30.6-1.40.70.9-0.0-1.11.11.3
Time in familiar zone, hab. session 10.50.53.20.20.20.60.40.2-0.8-0.20.01.80.30.51.1
Time in novel zone, hab. session 11.11.14.50.6-0.9-1.3-1.0-0.81.3-0.5-0.5-2.1-0.4-0.7-1.2
Total zone transitions, hab. session 10.50.83.1-1.80.91.50.71.2-0.10.50.5-0.1-0.2-0.1-0.5
Total locomotion distance, hab. session 10.40.51.3-0.2-0.60.0-0.7-0.21.0-0.7-0.90.20.9-1.0-1.1
Locomotion velocity, hab. session 10.30.40.8-0.6-0.20.4-0.40.00.6-0.6-0.70.60.9-0.8-0.9
Time in familiar zone, hab. session 21.21.33.20.7-0.9-0.6-0.9-1.20.7-1.3-1.31.81.7-1.0-0.4
Time in novel zone, hab. session 20.50.53.10.5-0.1-0.5-0.00.3-0.00.50.5-1.3-1.80.40.1
Total zone transitions, hab. session 21.11.42.9-1.41.31.61.31.7-1.01.01.3-0.5-1.00.90.7
Total locomotion distance, hab. session 20.60.71.7-0.60.91.30.91.3-0.80.80.8-0.4-0.60.80.7
Locomotion velocity, hab. session 20.60.92.0-0.81.01.41.01.3-0.90.80.9-0.4-0.60.80.7
Novel to familiar place preference ratio0.30.30.9-0.8-0.1-0.1-0.2-0.20.6-0.5-0.60.50.7-0.8-0.9
Novelty place preference0.40.41.3-0.7-0.2-0.2-0.4-0.30.8-0.6-0.60.30.6-1.0-1.2
Time in novel zone, NPP test0.50.61.4-0.3-0.5-0.5-0.6-0.60.9-0.9-0.90.50.7-1.1-1.2
Total zone transitions, NPP test1.72.54.9-1.11.61.81.72.2-1.71.81.90.2-1.21.61.5
Total locomotion distance, NPP test0.70.92.1-0.40.81.30.91.4-1.11.11.10.1-0.51.01.0
Locomotion velocity, NPP test1.01.43.2-1.01.21.71.21.8-1.21.31.3-0.2-0.51.10.9
Intraocular pressure2.13.17.7-2.21.92.81.72.7-0.72.01.7-1.3-0.80.8-0.1
Delta distance traveled before/after self-admin0.40.41.5-1.20.91.00.70.5-0.30.30.2-0.90.10.2-0.1
Delta ambulatory time before/after self-admin0.70.92.0-1.31.31.41.20.8-0.90.70.6-0.5-0.20.70.7
Parametrial fat weight0.20.53.01.3-0.7-0.4-0.50.1-0.1-0.3-0.61.7-0.1-0.00.5
Pavlov. Cond. lever latency0.70.84.7-1.71.00.70.70.2-0.10.20.2-2.2-0.60.1-0.2
Pavlov. Cond. magazine entry latency4.05.212.93.6-2.9-2.8-2.5-2.21.5-2.1-2.12.31.7-1.4-0.5
Pavlov. Cond. change in total contacts7.47.811.73.1-3.4-3.3-3.3-2.62.9-2.6-2.61.82.5-2.7-2.4
Pavlov. Cond. index score2.63.310.53.2-2.4-2.2-2.0-1.41.1-1.4-1.32.21.2-0.9-0.3
Pavlov. Cond. latency score1.92.48.02.8-2.0-1.8-1.6-1.20.8-1.1-1.12.20.9-0.7-0.1
Pavlov. Cond. lever contacts0.80.94.02.0-1.1-0.8-0.8-0.20.1-0.1-0.12.00.6-0.10.3
Pavlov. Cond. magazine entry number5.87.315.0-3.93.43.33.12.5-2.32.52.5-2.2-2.22.01.3
Pavlov. Cond. intertrial magazine entries0.40.51.4-1.20.80.90.60.8-0.20.60.5-1.2-0.50.2-0.2
Pavlov. Cond. lever-magazine prob. diff.3.34.012.33.5-2.6-2.4-2.3-1.71.4-1.6-1.52.21.5-1.1-0.5
Pavlov. Cond. response bias5.06.112.43.5-3.1-3.0-2.8-2.22.0-2.1-2.12.62.3-1.8-1.2
Pavlov. Cond. lever latency0.10.21.0-1.00.40.40.30.30.1-0.00.1-0.3-0.6-0.2-0.4
Pavlov. Cond. magazine entry latency0.10.20.5-0.10.30.60.30.5-0.40.50.2-0.2-0.70.40.4
Pavlov. Cond. change in total contacts0.10.21.21.0-0.4-0.4-0.3-0.30.10.10.1-1.1-0.10.30.3
Pavlov. Cond. index score0.10.20.50.50.10.30.20.3-0.50.50.3-0.3-0.10.60.7
Pavlov. Cond. latency score0.20.20.60.40.20.40.30.4-0.60.60.3-0.4-0.20.70.8
Pavlov. Cond. lever contacts0.10.20.91.0-0.3-0.2-0.1-0.1-0.30.10.00.40.50.30.6
Pavlov. Cond. magazine entry number0.00.00.1-0.30.1-0.10.10.10.1-0.10.30.00.3-0.1-0.3
Pavlov. Cond. intertrial magazine entries0.30.42.0-1.40.40.30.20.40.50.20.5-0.6-0.0-0.5-1.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.30.20.40.30.4-0.50.60.2-0.3-0.20.60.7
Pavlov. Cond. response bias0.20.31.71.3-0.7-0.6-0.5-0.40.0-0.2-0.40.60.30.00.4
Time in closed arm before self-admin1.21.52.31.3-1.5-1.3-1.5-1.11.4-1.2-1.00.01.4-1.2-1.1
Time in closed arm after self-admin0.60.62.7-0.5-0.2-0.6-0.4-1.10.7-0.8-0.5-0.61.6-0.8-0.8
Time in open arm before self-admin0.70.81.2-1.11.00.71.10.5-1.10.70.70.5-1.10.80.9
Time in open arm after self-admin0.10.10.8-0.50.40.40.30.4-0.20.20.0-0.3-0.90.20.1
Bone: periosteal estimation0.81.73.2-0.61.40.91.50.9-1.81.01.20.3-1.71.51.8
Bone: periosteal perimeter1.62.74.5-1.01.81.31.91.5-2.11.71.6-0.2-1.51.92.0
Bone: post-yield work0.91.32.4-1.41.31.01.30.9-1.11.21.4-0.2-1.61.00.7
Progressive ratio test 1 active lever presses0.20.30.50.2-0.5-0.4-0.6-0.50.6-0.7-0.70.60.2-0.7-0.6
Progressive ratio test 1 breakpoint0.20.20.40.1-0.4-0.3-0.4-0.40.5-0.5-0.60.40.2-0.6-0.5
Progressive ratio test 1 inactive lever presses0.71.01.50.5-1.1-1.1-1.1-1.01.1-1.1-1.10.80.1-1.2-1.2
Progressive ratio test 2 active lever presses0.40.41.21.1-0.9-0.9-0.9-0.30.7-0.5-0.40.10.2-0.5-0.5
Progressive ratio test 2 breakpoint0.40.41.21.1-0.9-0.9-0.9-0.30.7-0.5-0.50.10.3-0.5-0.4
Progressive ratio test 2 inactive lever presses0.10.10.20.4-0.4-0.2-0.40.20.4-0.2-0.2-0.4-0.1-0.2-0.3
Incentive Sensitization - Responses0.20.31.91.4-0.6-0.4-0.40.50.10.30.4-0.6-0.50.40.2
Incentive Sensitization - Breakpoint0.20.31.71.3-0.6-0.4-0.40.50.10.30.3-0.5-0.40.30.3
Sum of active levers in priming session hrs 5-60.90.92.70.0-0.4-0.6-0.4-1.30.2-1.0-1.11.61.6-0.6-0.1
Progressive ratio0.10.21.30.5-0.3-0.3-0.2-0.5-0.1-0.3-0.31.10.4-0.10.2
Food seeking constrained by brief footshock0.30.41.80.7-0.6-0.2-0.4-0.80.0-0.5-0.51.30.8-0.20.2
Seeking ratio, punishment vs. effort0.00.00.2-0.20.10.20.00.00.1-0.0-0.1-0.50.2-0.1-0.2
Retroperitoneal fat weight0.00.20.90.3-0.4-0.2-0.30.00.2-0.1-0.30.90.7-0.3-0.2
Reaction time number correct0.61.22.1-1.11.30.61.30.6-1.31.41.5-0.3-1.11.21.1
Reaction time mean minus median0.51.34.0-0.61.11.21.01.1-0.81.31.1-2.0-1.11.10.7
Reaction time mean minus median AUC0.20.52.2-0.10.50.60.50.5-0.40.90.6-1.5-0.60.70.4
Reaction time num false alarms0.30.51.90.70.2-0.10.40.1-1.00.70.70.50.31.01.4
Reaction time num false alarms AUC0.60.93.10.60.50.10.70.5-1.31.21.10.2-0.21.41.8
Reaction time trials correct on left0.61.22.1-1.11.30.61.30.6-1.31.41.5-0.3-1.11.21.1
Reaction time trials on left0.71.22.1-1.11.30.61.30.6-1.31.41.5-0.4-1.11.21.1
Reaction time mean0.61.01.70.6-1.0-0.7-1.1-1.11.2-1.1-1.1-0.61.3-1.0-1.1
Reaction time mean AUC0.81.32.40.6-1.1-0.9-1.2-1.31.3-1.3-1.3-0.41.6-1.2-1.2
Median of all reaction times1.92.73.81.2-1.8-1.4-1.8-1.81.8-1.9-1.80.12.0-1.7-1.5
Reaction time omissions0.20.30.50.6-0.7-0.6-0.7-0.70.6-0.5-0.50.00.5-0.4-0.4
Reaction time false alarm rate0.20.31.21.1-0.3-0.3-0.0-0.0-0.50.30.20.30.40.61.0
Reaction time premature initiation rate2.23.15.70.9-1.6-1.2-1.7-1.91.5-2.2-2.22.41.8-1.9-1.3
Reaction time premature initiations0.50.82.8-0.0-0.6-0.5-0.6-1.20.5-1.1-1.11.70.9-1.0-0.5
Std. dev. reaction times0.10.32.20.10.30.50.30.2-0.20.30.3-1.5-0.30.50.3
Reaction time trials completed0.71.22.1-1.11.30.61.30.6-1.31.41.5-0.4-1.11.21.1
Reaction time trials AUC0.71.32.3-1.01.30.61.30.7-1.31.41.5-0.6-1.11.21.1
Run reversals in cocaine runway, females1.31.34.5-1.4-0.3-0.3-0.6-0.81.4-1.0-1.00.50.7-1.7-2.1
Run reversals in cocaine runway, males0.30.30.60.3-0.6-0.3-0.7-0.10.8-0.6-0.70.4-0.4-0.7-0.8
Latency to leave start box in cocaine runway0.70.81.9-1.41.10.91.00.4-0.70.90.9-1.2-0.50.70.4
Latency to leave start box in cocaine runway, F0.40.52.4-1.51.00.90.80.2-0.40.50.5-0.3-0.30.2-0.1
Latency to leave start box in cocaine runway, M0.10.11.00.1-0.0-0.30.0-0.0-0.00.30.3-1.00.10.20.2
Std. dev. time between licks in bursts0.81.02.2-0.01.00.51.10.7-1.31.31.2-0.6-0.11.41.5
Total sessions with >9 infusions1.21.52.70.3-1.1-1.1-1.3-1.31.5-1.3-1.30.11.2-1.6-1.6
Short access day 1 total inactive lever presses1.31.72.71.3-1.6-1.2-1.6-1.31.5-1.3-1.40.30.2-1.4-1.4
Short access day 10 total inactive lever presses0.00.10.20.3-0.2-0.1-0.20.20.30.30.3-0.4-0.4-0.1-0.4
Short access day 1 total infusions2.83.86.10.4-1.7-1.7-2.0-2.22.2-2.2-2.31.31.5-2.5-2.3
Short access day 10 total infusions0.50.71.00.6-0.9-0.7-0.9-0.90.9-0.9-1.00.50.6-0.9-0.8
Short access total infusions1.82.33.40.6-1.4-1.3-1.6-1.71.6-1.7-1.81.21.1-1.9-1.7
Short access day 1 locomotion2.02.53.50.9-1.6-1.4-1.7-1.71.6-1.6-1.61.31.9-1.8-1.5
Short access day 10 total locomotion0.20.41.71.3-0.3-0.1-0.10.3-0.40.20.1-1.10.20.81.0
Short access total locomotion0.10.10.40.4-0.3-0.1-0.2-0.30.2-0.0-0.1-0.50.6-0.0-0.1
One hour access (0.3 mA shock)0.10.10.4-0.30.30.10.20.2-0.00.10.1-0.6-0.30.0-0.1
Compulsive drug intake0.60.73.3-0.3-0.2-1.0-0.4-0.41.0-0.1-0.2-1.8-0.2-0.8-1.4
One hour access (shock baseline)0.10.20.90.1-0.3-0.1-0.3-0.40.2-0.7-0.71.00.5-0.4-0.2
Social response proportion0.20.20.8-0.90.20.60.20.20.1-0.1-0.00.80.1-0.3-0.4
Social responses0.20.22.1-0.00.10.40.20.4-0.30.2-0.01.40.00.10.3
Social time1.01.43.2-0.11.01.11.11.4-1.41.21.10.4-1.81.41.4
Soleus weight0.72.15.2-0.11.30.91.51.1-2.11.51.20.8-1.31.82.3
Bone: stiffness0.20.43.0-0.1-0.1-0.3-0.1-0.8-0.2-0.6-0.51.7-0.5-0.20.2
Tibialis anterior weight0.62.15.4-2.32.02.11.81.5-1.51.30.90.3-0.40.90.8
Time to tail flick, vehicle, before self-admin1.61.73.30.00.91.11.01.8-1.01.51.7-1.3-1.51.41.0
Time to tail flick, vehicle, after self-admin0.30.41.10.50.30.30.40.5-0.70.80.80.5-1.00.80.8
Time to tail flick, test, before self-admin0.40.41.2-0.90.81.10.70.7-0.60.80.60.3-0.20.40.3
Time to tail flick, test, after self-admin1.31.32.2-0.00.90.91.11.5-1.31.51.4-0.6-0.81.51.5
Delta time to tail flick, vehicle, before/after SA0.40.41.30.8-0.0-0.20.2-0.2-0.80.10.11.1-0.60.71.1
Delta time to tail flick, test, before/after SA0.20.31.41.2-0.7-0.8-0.5-0.00.2-0.00.0-0.2-0.20.10.1
Tibia length1.13.05.0-2.22.12.22.11.6-1.91.31.50.9-1.81.31.3
Ambulatory time before self-admin0.20.30.90.3-0.5-0.2-0.5-0.60.5-0.3-0.50.90.2-0.6-0.6
Ambulatory time after self-admin0.50.52.0-1.10.91.40.80.3-0.70.30.10.6-0.50.30.3
Bone: tissue strength2.12.13.7-1.21.60.91.61.3-1.31.81.9-1.6-1.51.51.0
Total heroin consumption0.91.03.81.8-0.9-1.1-0.6-0.8-0.3-0.2-0.41.91.00.31.0
Bone: trabecular number2.13.59.03.0-2.2-2.4-1.9-2.00.8-1.9-1.52.31.8-0.80.1
Bone: trabecular spacing1.62.14.3-1.61.62.11.62.1-1.31.31.10.2-1.31.10.9
Bone: trabecular thickness0.30.41.00.20.4-0.10.5-0.1-0.80.50.7-0.7-0.80.91.0
Bone: trabecular tissue density0.60.93.1-0.3-0.7-0.6-0.9-0.61.4-0.7-0.9-0.7-0.0-1.3-1.7
Water consumed over 24 hours0.81.12.0-0.41.00.91.11.1-1.21.41.2-0.9-0.41.31.2
Number of responses in last shaping day0.50.63.80.4-0.4-0.8-0.6-0.40.7-0.4-0.5-1.90.1-0.4-0.5