Hub : Genes

LOC108352132

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr10_84326756_84327501 0.03 0.02 6.1e-03 0.01 0.01 0.02 0.01 1.3e-02 2.7e-02 1.2e-02 3.7e-02
2 LHb gene expression LOC108352132 0.14 0.09 6.7e-03 0.04 0.02 -0.01 0.01 4.5e-02 1.2e-01 5.3e-01 2.1e-01
3 Adipose isoform ratio XR_001840282.2 0.04 0.03 4.2e-06 0.03 0.04 0.03 0.04 3.1e-04 4.3e-05 3.1e-04 6.8e-05
4 OFC gene expression LOC108352132 0.66 0.14 1.0e-11 0.4 0.34 0.33 -0 1.7e-10 8.7e-09 1.2e-08 4.3e-01
5 Brain gene expression LOC108352132 0.07 0.04 4.7e-08 0.09 0.08 0.08 0.09 1.2e-08 3.6e-08 3.9e-08 1.3e-08
6 Liver gene expression LOC108352132 0.03 0.02 1.0e-04 0.04 0.04 0.03 0.04 3.3e-05 5.9e-05 1.7e-04 8.7e-05
7 Brain isoform ratio XR_001840282.2 0.03 0.02 1.0e-03 0.02 0.04 0.04 0.04 5.5e-03 2.1e-04 1.5e-04 1.9e-04
8 Adipose gene expression LOC108352132 0.02 0.01 5.3e-03 0.01 0.01 0.01 0.01 4.0e-02 1.1e-02 9.2e-03 1.7e-02
9 Brain isoform ratio XR_005490448.1 0.03 0.02 1.8e-03 0.02 0.03 0.03 0.03 6.2e-03 4.3e-04 4.5e-04 5.8e-04
10 LHb isoform ratio XR_001840282.2 0.33 0.15 6.4e-04 0.11 0.18 0.12 0.14 1.5e-03 5.7e-05 7.5e-04 3.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.11.86.01.81.91.3-2.4-1.10.9-0.20.7-0.1-1.1
Area under the delay curve1.11.22.21.00.31.1-0.9-1.11.4-1.50.9-1.30.7
BMI with tail1.34.211.0-3.3-1.5-2.51.82.1-1.42.0-2.12.0-0.9
BMI without tail0.10.20.6-0.8-0.3-0.50.80.5-0.20.4-0.40.4-0.1
Body weight2.29.325.0-5.0-3.1-3.82.43.1-2.83.1-1.82.7-0.9
Weight adjusted by age0.20.20.7-0.3-0.8-0.2-0.6-0.1-0.00.30.60.2-0.6
Bone surface0.40.82.3-0.30.4-0.6-1.00.6-0.61.2-0.21.2-1.5
Bone volume0.71.23.9-0.20.9-0.5-1.20.5-0.61.4-0.51.5-2.0
Breakpoint value in progressive ratio session0.20.21.2-0.10.30.3-0.5-0.21.1-0.30.0-0.0-0.5
Number of licking bursts0.70.83.2-0.30.6-0.7-0.20.8-0.31.0-0.81.3-1.8
Context. condit. distance diff. score1.11.35.5-0.0-0.70.50.6-0.60.4-1.31.2-1.72.3
Locomotion velocity, session 10.40.41.3-1.10.5-0.6-0.00.5-0.00.40.20.9-1.0
Locomotion distance, session 11.21.53.7-1.9-0.5-1.60.61.4-0.71.2-0.71.4-1.3
Locomotion velocity, session 20.10.20.9-0.4-0.00.1-0.1-0.10.6-0.50.9-0.30.1
Locomotion distance, session 20.30.52.1-0.6-0.2-0.7-0.40.7-0.20.60.20.9-1.4
Locomotion velocity, session 30.50.52.10.60.10.6-0.1-0.50.7-0.91.4-0.80.5
Locomotion distance, session 30.10.10.2-0.2-0.3-0.40.40.50.2-0.10.40.1-0.1
Stereotopy head waving bouts, day 32.22.64.61.81.52.1-1.5-2.10.9-1.31.9-1.40.7
Stereotopy head waving duration, day 30.40.41.20.20.30.8-0.9-1.1-0.3-0.20.9-0.50.5
Locomotion velocity, session 72.02.13.4-1.5-1.3-1.71.01.7-1.81.8-0.71.7-1.0
Locomotion distance, session 71.41.73.7-0.7-1.9-1.61.41.7-1.51.4-0.51.0-0.2
Stereotopy head waving bouts, day 70.80.92.00.51.31.1-1.4-1.31.0-0.70.7-0.6-0.3
Stereotopy head waving duration, day 71.11.32.70.51.51.3-1.6-1.61.2-1.00.8-0.8-0.2
Locomotion velocity, session 81.72.05.6-2.4-2.0-1.52.01.3-0.90.0-0.1-0.11.3
Locomotion distance, session 80.10.20.7-0.8-0.6-0.50.40.40.1-0.20.6-0.10.2
Degree of sensitization distance1.71.74.2-1.0-2.1-1.41.61.5-1.81.2-0.50.60.6
Degree of sensitization stereotypy0.91.02.20.81.51.1-1.4-1.21.3-0.80.4-0.5-0.6
Conditioned locomotion0.50.61.10.50.70.9-0.9-0.80.7-0.51.1-0.70.3
Cocaine response after cond. corrected0.80.92.40.61.20.7-1.5-0.90.6-0.31.0-0.0-1.2
Cocaine response after cond. not corrected0.70.82.80.70.70.6-1.7-0.8-0.10.11.30.2-1.2
Cocaine response before conditioning0.30.41.50.4-1.1-0.2-0.10.2-1.20.70.30.10.4
Saline control response0.20.20.5-0.7-0.7-0.5-0.20.3-0.40.5-0.00.3-0.4
Bone: connectivity density1.52.36.82.21.81.6-2.6-1.31.3-0.51.0-0.4-0.9
Bone: cortical apparent density2.43.19.13.02.22.3-1.0-1.91.2-1.60.7-1.50.8
Bone: cortical area0.10.10.5-0.10.3-0.1-0.20.2-0.20.50.70.4-0.4
Bone: cortical porosity0.50.51.5-0.01.00.1-1.1-0.30.50.4-0.80.6-1.2
Bone: cortical porosity0.40.41.4-0.00.80.0-1.2-0.30.60.3-0.50.5-1.2
Bone: cortical thickness1.21.95.31.41.11.5-1.3-1.31.3-1.12.3-1.20.6
Bone: cortical thickness7.08.112.43.12.53.3-3.1-3.22.7-2.73.5-2.50.6
Bone: cortical tissue density2.33.18.93.02.22.3-1.0-1.91.2-1.60.6-1.40.7
Condit. Reinf. active minus inactive responses1.92.13.71.51.41.6-0.9-1.51.7-1.91.2-1.60.8
Condit. Reinf. active-inactive response ratio2.32.53.91.61.11.8-1.0-1.62.0-1.91.6-1.81.1
Condit. Reinf. active responses1.41.83.51.41.31.5-0.6-1.31.6-1.91.0-1.40.7
Condit. Reinf. inactive responses0.10.10.30.30.50.10.00.00.3-0.30.10.1-0.5
Incentive salience index mean1.21.43.01.71.01.3-0.9-1.11.2-1.41.2-1.10.3
Condit. Reinf. lever presses0.10.20.91.0-0.30.1-0.10.2-0.20.20.50.1-0.4
Condit. Reinf. active minus inactive responses0.30.41.21.00.80.1-0.70.10.00.10.10.4-1.1
Condit. Reinf. active-inactive response ratio0.30.31.11.1-0.2-0.2-0.50.4-0.40.3-0.00.5-0.9
Condit. Reinf. active responses0.60.83.01.01.60.3-1.1-0.10.40.10.00.7-1.7
Condit. Reinf. inactive responses0.81.04.00.82.00.8-1.2-0.60.8-0.10.10.4-1.4
Condit. Reinf. lever presses0.20.20.80.30.60.4-0.5-0.30.9-0.70.3-0.2-0.3
Condit. Reinf. lever reinforcers received0.70.93.01.21.70.6-1.2-0.30.7-0.20.30.3-1.5
Conditioned reinforcement - actives0.10.10.70.90.10.1-0.00.0-0.20.2-0.20.0-0.1
Conditioned reinforcement - inactives0.40.41.71.30.60.40.1-0.2-1.00.5-0.80.10.3
Conditioned locomotion0.20.31.00.30.1-0.30.30.5-0.00.7-0.50.7-1.0
Patch foraging indifference point 0 sec0.40.73.41.8-0.20.7-0.3-0.1-0.1-0.41.5-0.60.5
Patch foraging indifference point AUC0.10.10.3-0.5-0.1-0.2-0.10.20.40.4-0.20.4-0.5
Delay disc. indifference point, 0s delay0.70.71.70.91.20.9-1.0-0.81.3-0.60.4-0.5-0.3
Delay disc. indifference point, 16s delay5.15.19.51.50.82.4-1.5-2.52.8-3.12.3-2.81.9
Delay disc. indifference point, 2s delay0.30.31.10.60.60.2-0.7-0.10.30.2-0.20.4-1.1
Delay disc. indifference point, 24s delay0.50.51.20.4-0.30.20.40.00.5-0.91.1-1.01.0
Delay disc. indifference point, 4s delay2.02.13.41.50.91.7-1.8-1.81.8-1.51.0-1.40.2
Delay disc. indifference point, 8s delay0.00.00.20.40.10.0-0.10.0-0.1-0.10.2-0.1-0.0
Indifference point function ln k0.40.51.90.4-0.40.6-0.1-0.5-0.4-0.41.0-1.01.4
Indifference point function log k0.40.51.90.4-0.40.6-0.1-0.5-0.4-0.41.0-1.01.4
Patch foraging total patch changes 0 sec0.30.52.31.5-0.50.3-0.10.2-0.4-0.11.2-0.30.3
Patch foraging total patch changes 12 sec1.31.74.52.11.50.9-1.6-0.61.3-0.00.90.5-1.9
Patch foraging total patch changes 18 sec0.20.20.70.20.3-0.30.00.70.10.6-0.20.7-0.8
Patch foraging total patch changes 24 sec0.81.02.01.11.10.9-1.4-0.71.3-0.51.1-0.3-0.8
Patch foraging total patch changes 6 sec0.40.73.51.9-0.20.8-0.7-0.40.4-0.21.1-0.5-0.0
Patch foraging time to switch 0 sec0.20.20.80.30.90.2-0.5-0.20.8-0.50.1-0.0-0.6
Patch foraging water rate 0 sec0.00.10.10.3-0.30.20.1-0.1-0.20.20.3-0.20.4
Patch foraging water rate 12 sec0.00.10.4-0.20.60.2-0.4-0.10.00.20.2-0.0-0.0
Patch foraging water rate 18 sec0.50.62.00.80.60.5-1.4-0.6-0.10.21.30.0-0.8
Patch foraging water rate 24 sec0.10.21.21.10.00.2-0.5-0.1-0.10.30.10.1-0.3
Patch foraging water rate 6 sec1.01.52.71.61.71.3-1.5-1.01.4-0.81.1-0.7-0.4
Seeking ratio, delayed vs. immediate footshock1.82.14.21.40.61.5-0.2-1.31.1-1.91.1-2.02.1
Distance traveled before self-admin0.10.10.80.0-0.9-0.1-0.3-0.1-0.50.40.1-0.1-0.0
Distance traveled after self-admin0.60.72.6-1.6-1.0-0.60.70.3-0.90.6-0.90.20.3
Extensor digitorum longus weight4.015.935.4-6.0-5.3-4.54.94.1-3.52.7-3.11.81.6
Bone: elastic displacement0.30.30.8-0.3-0.3-0.60.90.7-0.60.5-0.50.5-0.0
Bone: elastic work0.20.31.10.11.00.3-0.9-0.30.60.10.60.2-0.7
Bone: endosteal estimation2.65.68.2-2.9-1.4-2.71.32.4-2.72.8-2.42.7-1.7
Bone: endosteal perimeter1.93.95.2-2.2-1.1-2.31.72.2-1.92.2-2.32.2-1.1
Epididymis fat weight0.41.01.9-0.6-1.2-1.00.20.9-1.21.4-0.31.3-0.9
Delta time in closed arm before/after self-admin0.80.83.0-1.7-0.6-1.11.10.9-0.70.5-0.70.40.3
Delta time in open arm before/after self-admin0.20.20.70.0-0.10.4-0.3-0.6-0.0-0.4-0.8-0.40.7
Diff in mean of infusions in LGA sessions0.10.10.3-0.50.10.1-0.4-0.20.20.30.10.2-0.5
Delay discount exponential model param1.11.22.4-1.0-0.1-1.10.81.1-1.41.6-1.01.4-0.8
Extinction: sum of active levers before priming1.51.52.8-1.7-0.8-1.50.91.3-0.91.6-0.91.3-0.6
Active lever presses in extinction session 61.91.96.00.71.60.8-2.5-1.21.10.10.20.6-2.4
Bone: final force0.61.03.30.30.8-0.1-1.60.0-0.51.01.11.0-1.8
Bone: final moment0.61.03.10.10.7-0.2-1.40.2-0.71.11.01.1-1.8
Food consumed during 24 hour testing period0.40.50.8-0.8-0.9-0.80.90.6-0.40.5-0.90.40.0
Glucose0.20.40.7-0.50.8-0.1-0.7-0.00.00.8-0.70.7-0.8
Heart weight1.92.64.7-2.1-1.7-1.92.21.8-2.01.4-0.50.80.8
Delay discount hyperbolic model param1.01.12.0-1.0-0.2-1.10.91.1-1.31.4-1.01.3-0.7
Intermittent access intake day 1-15 change1.21.27.00.22.61.1-1.1-1.00.6-0.4-0.90.0-0.4
Intermittent access intake escalation1.51.58.50.32.91.2-1.3-1.21.0-0.5-0.7-0.1-0.5
Intermittent access intake escalation 20.60.63.6-0.31.90.3-0.3-0.20.6-0.0-1.00.5-0.8
Intermitt. access day 1 inactive lever presses2.72.95.91.90.92.1-2.4-2.41.6-1.41.5-1.30.1
Intermitt. access day 15 inactive lever presses2.42.64.82.22.22.1-1.9-2.01.4-1.00.4-1.10.0
Intermitt. access escalation Index0.20.21.4-1.2-0.3-0.4-0.20.10.10.10.50.0-0.1
Intermittent access day 1 total infusions0.10.10.70.8-0.40.2-0.2-0.3-0.20.20.4-0.30.2
Intermittent access day 15 total infusions1.41.63.91.12.01.6-1.5-1.71.1-1.00.4-1.00.3
Intermittent access terminal intake (last 3 days)0.80.92.01.11.41.3-1.2-1.30.6-0.50.2-0.70.1
Intermittent access total infusions0.50.61.21.00.71.0-0.9-1.10.5-0.50.6-0.80.4
Intermittent access day 1 locomotion0.40.40.90.1-0.6-0.40.60.4-0.80.9-0.80.6-0.1
Intermittent access day 15 total locomotion1.01.14.1-0.20.4-0.60.90.8-1.01.2-2.01.3-0.8
Intermittent access total locomotion0.20.20.80.50.70.30.2-0.1-0.30.3-0.90.3-0.2
Intermittent access standard deviation1.71.85.21.72.31.7-1.2-1.51.3-1.00.2-0.80.1
Left kidney weight0.61.66.2-1.20.30.6-0.5-0.81.5-1.52.5-1.31.0
Right kidney weight0.41.23.6-0.41.20.8-1.5-1.31.0-0.91.9-0.6-0.3
Cocaine induced anxiety0.30.31.2-1.1-0.2-0.5-0.30.2-0.0-0.00.9-0.0-0.6
Post-drug Anxiety0.30.41.10.1-0.40.4-0.6-0.60.3-0.71.0-0.90.3
Baseline Anxiety0.30.31.21.1-0.30.60.2-0.3-0.2-0.5-0.3-0.51.0
Tail length0.10.31.0-0.2-0.50.20.2-0.30.2-0.61.0-0.80.9
Length with tail0.51.75.8-2.4-2.1-1.30.81.0-1.30.80.60.20.8
Length without tail1.02.26.9-2.6-1.9-1.80.21.3-1.61.6-0.31.2-0.5
Times rat made contact with spout0.20.30.70.70.1-0.20.20.3-0.60.6-0.80.6-0.6
Lifetime Intake0.91.01.91.20.71.2-1.2-1.40.5-0.70.9-1.10.6
Liver weight, left0.10.10.60.30.00.2-0.3-0.20.8-0.00.3-0.1-0.2
Liver weight, right2.33.99.51.21.82.2-3.1-2.72.0-1.52.2-1.4-0.2
Locomotor activity0.50.83.50.61.10.2-1.1-0.30.70.20.40.8-1.9
Locomotor testing distance0.81.43.71.71.91.2-1.5-1.01.1-0.50.5-0.1-1.2
Locomotor testing rearing3.45.310.63.32.42.7-2.6-2.52.4-2.01.8-1.6-0.0
Locomotion in novel chamber3.84.78.62.92.22.5-2.4-2.52.0-1.82.2-1.90.1
Locomotion in novel chamber post-restriction0.50.62.30.30.8-0.3-0.10.3-0.50.7-0.81.1-1.5
Fecal boli incidents, locomotor time 11.71.85.1-1.2-0.5-1.31.61.3-1.51.3-2.31.2-0.3
Change in fecal boli incidents, locomotor task0.50.41.70.10.70.4-0.6-0.40.9-0.71.3-0.4-0.1
Time >=10cm from walls, locomotor time 10.30.30.70.50.40.50.0-0.30.4-0.70.8-0.60.7
Bouts of movement, locomotor time 10.10.10.4-0.4-0.6-0.2-0.1-0.1-0.30.4-0.40.2-0.1
Total resting periods, locomotor time 10.70.71.5-0.9-1.2-0.90.50.5-0.91.0-1.00.7-0.3
Rest time, locomotor task time 11.71.84.3-0.6-1.2-1.20.51.0-1.42.0-2.11.6-1.1
Distance moved, locomotor task time 12.02.24.20.81.51.4-0.9-1.31.8-2.01.9-1.70.8
Vertical activity count, locomotor time 10.20.20.5-0.20.50.2-0.1-0.00.6-0.70.5-0.40.2
Time >=10cm from walls, locomotor time 20.50.51.50.81.20.3-0.9-0.20.60.10.60.4-1.2
Bouts of movement, locomotor time 20.70.72.40.8-0.50.8-1.2-0.80.8-0.61.5-0.60.2
Total resting periods, locomotor time 20.80.82.40.7-0.80.8-1.1-0.90.7-0.71.5-0.80.5
Rest time, locomotor task time 21.01.22.0-1.0-1.4-1.10.90.9-1.41.2-1.20.9-0.1
Distance moved, locomotor task time 20.30.40.9-0.20.90.3-0.5-0.50.9-0.60.9-0.5-0.0
Vertical activity count, locomotor time 20.10.10.3-0.60.3-0.10.30.10.4-0.5-0.0-0.30.3
Light reinforcement 11.32.46.32.51.71.6-1.8-1.31.4-0.61.8-0.6-0.8
Light reinforcement 20.60.81.90.80.90.5-1.4-0.61.4-0.50.6-0.1-1.1
Bone: marrow area2.45.27.6-2.7-1.3-2.71.32.4-2.62.7-2.32.6-1.7
Bone: maximum diameter0.10.20.7-0.10.4-0.3-0.10.2-0.00.6-0.10.7-0.9
Bone: maximum force0.61.02.3-0.80.1-0.8-0.70.7-1.21.50.31.4-1.4
Bone: maximum moment0.61.02.4-0.9-0.1-0.9-0.40.9-1.31.60.31.3-1.2
Mean time between licks in bursts3.54.97.2-2.3-1.3-2.52.42.7-2.52.5-2.02.4-1.1
Mean num. licks in bursts0.50.62.10.9-0.40.70.2-0.80.1-0.80.3-1.11.4
Cd content in liver0.30.30.90.5-0.50.6-0.5-0.90.0-0.4-0.3-0.70.7
Co content in liver0.60.72.7-0.0-1.3-0.01.2-0.1-0.5-0.7-0.3-1.01.7
Cu content in liver0.80.92.01.1-0.10.8-0.0-0.80.8-1.40.5-1.41.4
Fe content in liver0.10.10.8-0.9-0.5-0.4-0.10.20.3-0.10.1-0.0-0.2
K content in liver2.72.76.41.22.41.8-2.5-1.81.7-1.21.2-0.8-0.7
Mg content in liver3.73.85.71.62.32.4-1.8-2.12.2-2.21.5-1.90.9
Mn content in liver3.13.510.11.73.22.1-1.9-1.72.3-1.41.6-0.9-0.4
Na content in liver1.31.33.40.11.60.3-1.8-0.50.20.7-1.50.9-1.8
Rb content in liver0.70.92.11.40.51.0-0.5-0.91.0-1.30.8-1.00.4
Se content in liver5.46.69.52.83.03.1-2.7-3.02.8-2.52.2-2.00.1
Sr content in liver0.30.20.80.3-0.20.40.2-0.30.3-0.40.9-0.60.7
Zn content in liver1.01.14.12.00.61.4-0.9-1.30.6-0.80.3-1.00.2
Bone: minimum diameter0.50.92.4-1.6-0.2-1.00.30.8-1.01.3-0.71.2-0.8
Time in familiar zone, hab. session 10.80.83.3-0.21.0-0.1-1.3-0.10.80.30.10.8-1.8
Time in novel zone, hab. session 10.70.72.81.10.10.70.9-0.4-0.5-0.50.2-0.91.7
Total zone transitions, hab. session 10.50.72.7-0.8-1.6-0.71.10.5-0.0-0.4-0.1-0.51.2
Total locomotion distance, hab. session 10.50.81.50.6-0.10.7-0.2-0.81.2-1.20.8-1.21.0
Locomotion velocity, hab. session 10.40.51.10.0-0.40.5-0.2-0.61.1-1.10.7-1.00.9
Time in familiar zone, hab. session 21.92.05.20.82.31.3-1.7-1.42.0-1.50.7-0.8-0.6
Time in novel zone, hab. session 20.60.62.60.1-1.0-0.40.70.6-1.61.10.10.50.3
Total zone transitions, hab. session 20.71.01.8-1.0-1.4-1.31.21.2-1.00.7-0.60.60.1
Total locomotion distance, hab. session 20.40.50.9-0.6-0.8-0.90.70.8-0.40.7-0.90.7-0.3
Locomotion velocity, hab. session 20.40.61.0-0.7-0.9-1.00.80.9-0.40.7-0.80.7-0.3
Novel to familiar place preference ratio0.40.41.2-0.3-0.40.4-0.1-0.60.5-0.90.7-1.01.1
Novelty place preference0.60.61.8-0.2-0.40.50.0-0.60.5-1.00.9-1.21.4
Time in novel zone, NPP test0.70.71.50.1-0.00.8-0.3-0.90.7-1.11.2-1.21.2
Total zone transitions, NPP test1.21.83.3-1.0-1.3-1.80.91.8-1.21.4-1.01.4-1.1
Total locomotion distance, NPP test0.50.61.2-0.4-0.6-1.10.41.1-0.30.9-0.61.0-0.9
Locomotion velocity, NPP test0.71.01.8-0.7-1.2-1.30.91.4-0.71.0-0.90.9-0.5
Intraocular pressure2.13.08.1-1.5-2.9-1.82.81.7-0.90.3-1.60.01.4
Delta distance traveled before/after self-admin0.40.42.1-1.50.3-0.40.80.3-0.3-0.0-0.70.10.4
Delta ambulatory time before/after self-admin0.50.62.7-1.60.7-0.60.60.5-0.20.3-1.10.6-0.4
Parametrial fat weight0.61.23.41.80.91.0-1.7-1.00.40.41.20.1-1.1
Pavlov. Cond. lever latency0.50.72.2-1.5-0.0-0.41.20.3-0.1-0.2-1.0-0.21.3
Pavlov. Cond. magazine entry latency3.54.510.73.32.62.3-2.6-2.22.0-1.21.5-0.7-1.3
Pavlov. Cond. change in total contacts4.75.112.23.51.22.7-2.1-2.52.0-2.22.2-2.20.8
Pavlov. Cond. index score1.62.07.82.81.21.4-1.9-1.30.8-0.31.1-0.2-1.4
Pavlov. Cond. latency score1.11.45.22.30.91.0-1.7-1.00.50.00.90.1-1.4
Pavlov. Cond. lever contacts0.40.41.61.2-0.4-0.0-0.60.1-0.30.60.40.5-1.3
Pavlov. Cond. magazine entry number4.15.114.4-3.8-2.5-2.62.52.4-2.21.6-1.61.10.9
Pavlov. Cond. intertrial magazine entries0.40.51.1-1.0-0.5-0.51.00.5-0.5-0.2-0.9-0.20.9
Pavlov. Cond. lever-magazine prob. diff.1.82.38.93.01.41.5-1.9-1.40.9-0.41.3-0.3-1.3
Pavlov. Cond. response bias3.23.911.63.41.62.2-2.3-2.01.9-1.32.0-1.1-0.6
Pavlov. Cond. lever latency0.20.20.9-0.3-1.0-0.20.30.1-0.30.10.2-0.30.8
Pavlov. Cond. magazine entry latency0.10.10.7-0.2-0.2-0.30.40.2-0.80.4-0.40.3-0.1
Pavlov. Cond. change in total contacts0.10.10.70.50.90.30.00.0-0.10.1-0.20.2-0.3
Pavlov. Cond. index score0.10.20.7-0.00.7-0.10.10.2-0.30.3-0.40.6-0.8
Pavlov. Cond. latency score0.20.20.6-0.10.5-0.30.30.3-0.50.5-0.60.7-0.8
Pavlov. Cond. lever contacts0.30.41.60.51.10.2-0.6-0.00.30.10.00.5-1.3
Pavlov. Cond. magazine entry number0.10.10.60.1-0.8-0.10.00.20.5-0.1-0.2-0.20.4
Pavlov. Cond. intertrial magazine entries0.81.14.7-0.7-2.2-0.51.00.6-0.3-0.40.4-0.81.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.10.6-0.20.10.2-0.40.4-0.40.5-0.7
Pavlov. Cond. response bias0.40.52.00.81.40.6-0.8-0.50.3-0.20.40.2-1.1
Time in closed arm before self-admin0.70.82.10.41.41.0-0.4-0.61.1-1.11.1-0.60.1
Time in closed arm after self-admin0.70.71.5-0.61.10.50.3-0.21.0-1.21.1-0.90.9
Time in open arm before self-admin0.50.61.4-0.9-1.2-0.80.40.6-0.91.00.30.5-0.1
Time in open arm after self-admin0.50.61.3-0.5-1.2-0.70.70.5-1.20.9-0.80.40.3
Bone: periosteal estimation0.71.53.0-1.3-0.2-1.30.31.2-1.41.7-0.81.7-1.4
Bone: periosteal perimeter1.32.23.6-1.7-0.3-1.70.91.7-1.31.9-1.11.9-1.4
Bone: post-yield work1.31.73.2-1.6-1.6-1.50.91.6-1.81.4-0.30.9-0.1
Progressive ratio test 1 active lever presses0.40.51.00.90.20.9-0.9-1.00.3-0.20.5-0.70.5
Progressive ratio test 1 breakpoint0.40.41.10.80.20.9-0.9-1.00.2-0.10.4-0.70.5
Progressive ratio test 1 inactive lever presses1.51.63.11.80.81.6-1.7-1.70.7-0.61.1-1.20.7
Progressive ratio test 2 active lever presses0.30.31.61.30.60.7-0.5-0.60.1-0.1-0.2-0.30.2
Progressive ratio test 2 breakpoint0.20.21.01.00.60.6-0.5-0.5-0.00.0-0.3-0.20.2
Progressive ratio test 2 inactive lever presses0.20.31.01.00.90.6-0.4-0.50.1-0.2-0.1-0.30.1
Incentive Sensitization - Responses0.60.61.60.9-0.0-0.40.70.7-0.90.8-1.20.8-0.4
Incentive Sensitization - Breakpoint0.50.61.70.80.2-0.30.60.7-0.80.8-1.30.9-0.6
Sum of active levers in priming session hrs 5-61.21.12.50.61.51.0-1.6-1.31.6-0.60.4-0.4-0.7
Progressive ratio0.20.20.9-0.10.4-0.0-0.60.10.10.6-0.30.5-1.0
Food seeking constrained by brief footshock0.30.41.00.30.70.3-1.0-0.41.0-0.10.20.2-0.9
Seeking ratio, punishment vs. effort0.00.00.20.00.10.10.2-0.20.2-0.40.0-0.20.3
Retroperitoneal fat weight0.10.31.8-0.4-0.4-0.3-0.30.0-0.40.71.40.4-0.3
Reaction time number correct0.81.21.9-0.9-1.2-1.30.81.4-1.21.4-0.91.1-0.3
Reaction time mean minus median1.31.73.2-0.8-1.4-1.31.71.2-1.81.2-1.80.90.3
Reaction time mean minus median AUC0.70.92.6-0.2-0.9-0.81.30.8-1.20.9-1.60.60.2
Reaction time num false alarms0.70.93.60.41.2-0.4-0.50.6-0.10.9-0.81.3-1.9
Reaction time num false alarms AUC1.01.44.70.11.1-0.8-0.21.1-0.41.4-0.91.7-2.2
Reaction time trials correct on left0.81.21.9-0.9-1.2-1.30.81.4-1.21.4-0.91.1-0.3
Reaction time trials on left0.81.21.9-0.9-1.2-1.30.81.4-1.21.4-1.01.1-0.4
Reaction time mean0.50.71.30.90.71.1-0.3-1.00.9-1.20.2-1.00.8
Reaction time mean AUC0.70.91.70.90.71.2-0.4-1.21.0-1.30.2-1.20.9
Median of all reaction times1.52.13.21.61.51.8-1.0-1.61.6-1.70.9-1.50.7
Reaction time omissions0.30.41.81.30.70.8-0.7-0.70.1-0.40.2-0.2-0.4
Reaction time false alarm rate0.50.83.00.51.5-0.0-0.60.30.20.6-0.41.0-1.7
Reaction time premature initiation rate2.83.86.31.21.82.2-2.2-2.52.4-1.92.1-1.70.2
Reaction time premature initiations0.81.12.00.50.81.1-1.4-1.41.4-0.81.3-0.90.1
Std. dev. reaction times0.40.52.0-0.2-0.4-0.51.00.5-0.90.5-1.40.50.2
Reaction time trials completed0.81.21.9-0.9-1.2-1.30.81.4-1.21.4-1.01.1-0.4
Reaction time trials AUC0.81.22.1-0.9-1.1-1.30.91.4-1.11.4-1.01.1-0.3
Run reversals in cocaine runway, females2.12.16.40.0-1.00.60.1-0.70.4-1.72.2-2.12.5
Run reversals in cocaine runway, males0.70.71.31.20.10.9-0.4-0.90.5-1.10.8-1.00.8
Latency to leave start box in cocaine runway0.30.31.4-1.2-0.3-0.60.90.6-0.00.10.20.20.3
Latency to leave start box in cocaine runway, F0.20.20.9-1.0-0.8-0.30.40.10.3-0.20.2-0.20.5
Latency to leave start box in cocaine runway, M0.40.41.50.41.10.40.1-0.20.4-0.41.2-0.30.2
Std. dev. time between licks in bursts0.91.02.2-0.90.3-1.10.51.2-0.71.2-0.51.5-1.4
Total sessions with >9 infusions1.21.32.01.30.61.4-1.3-1.41.0-1.11.0-1.30.8
Short access day 1 total inactive lever presses1.21.34.52.10.31.4-1.4-1.6-0.0-0.20.8-1.10.8
Short access day 10 total inactive lever presses0.20.20.60.4-0.60.4-0.6-0.5-0.0-0.50.8-0.50.4
Short access day 1 total infusions2.72.84.91.90.62.0-2.0-2.21.0-1.41.9-1.91.2
Short access day 10 total infusions0.20.20.60.80.40.5-0.7-0.7-0.10.30.1-0.2-0.1
Short access total infusions1.92.13.71.60.61.7-1.7-1.90.8-1.11.7-1.71.1
Short access day 1 locomotion1.92.15.82.40.61.7-1.7-1.71.4-0.91.3-1.10.1
Short access day 10 total locomotion0.80.93.00.10.3-0.30.40.4-0.91.3-1.71.3-1.1
Short access total locomotion0.10.10.40.7-0.50.20.0-0.2-0.30.4-0.30.00.3
One hour access (0.3 mA shock)0.10.10.20.20.40.3-0.1-0.3-0.30.2-0.3-0.20.4
Compulsive drug intake1.01.13.4-0.2-1.4-0.61.40.9-1.30.40.1-0.41.8
One hour access (shock baseline)0.50.61.50.71.00.8-1.2-1.10.7-0.20.3-0.2-0.5
Social response proportion0.10.10.4-0.4-0.5-0.10.00.0-0.0-0.50.7-0.40.4
Social responses0.10.10.6-0.20.3-0.1-0.5-0.0-0.2-0.00.40.2-0.8
Social time1.41.94.9-0.6-0.8-1.50.61.3-2.21.7-1.11.6-1.3
Soleus weight0.71.94.9-1.30.3-1.3-0.21.1-1.11.8-1.12.0-2.2
Bone: stiffness0.20.41.7-0.20.10.0-1.3-0.3-0.60.50.70.4-0.7
Tibialis anterior weight0.51.75.4-2.3-1.9-1.50.80.9-0.80.7-1.70.70.0
Time to tail flick, vehicle, before self-admin1.31.43.0-0.1-1.5-1.21.71.5-1.41.1-0.90.9-0.0
Time to tail flick, vehicle, after self-admin0.80.82.70.2-1.6-0.80.60.8-1.41.1-0.70.6-0.2
Time to tail flick, test, before self-admin0.70.71.4-0.9-0.5-1.01.21.0-1.10.5-0.70.50.1
Time to tail flick, test, after self-admin0.80.81.4-0.2-0.6-1.01.21.1-1.00.9-0.90.9-0.6
Delta time to tail flick, vehicle, before/after SA0.70.71.90.0-0.1-0.4-0.50.2-0.71.1-1.11.1-1.4
Delta time to tail flick, test, before/after SA0.20.21.21.1-0.30.30.0-0.10.3-0.10.3-0.2-0.1
Tibia length0.82.25.2-2.3-2.0-1.90.91.4-1.41.4-0.51.2-0.6
Ambulatory time before self-admin0.40.42.30.3-1.5-0.20.30.0-0.90.30.2-0.30.6
Ambulatory time after self-admin1.11.24.1-2.0-1.1-1.00.90.7-1.41.0-1.00.60.1
Bone: tissue strength2.12.14.2-1.3-1.6-1.81.62.0-1.31.6-0.81.4-0.2
Total heroin consumption0.91.15.01.11.00.1-1.2-0.10.50.8-0.31.1-2.2
Bone: trabecular number2.43.710.92.62.71.8-3.3-1.71.6-0.50.6-0.1-1.7
Bone: trabecular spacing1.11.42.6-1.6-1.4-1.51.31.2-1.20.9-1.10.8-0.3
Bone: trabecular thickness0.30.40.8-0.10.8-0.3-0.20.5-0.60.9-0.20.9-0.8
Bone: trabecular tissue density0.81.14.10.7-0.90.70.6-0.70.1-0.81.5-1.42.0
Water consumed over 24 hours0.40.50.8-0.4-0.1-0.80.70.8-0.60.8-0.70.9-0.6
Number of responses in last shaping day1.01.02.50.71.61.3-1.1-1.20.7-1.00.2-0.80.6