Hub : Genes

LOC108352124

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC108352124 0.13 0.09 6.4e-03 0.07 0.05 0.04 0.04 8.0e-03 2.9e-02 4.6e-02 3.3e-02
2 NAcc gene expression LOC108352124 0.06 0.04 4.6e-08 0.07 0.07 0.07 0.07 2.2e-08 2.3e-08 1.4e-08 9.7e-09
3 RMTg intron excision ratio chr10_81978783_81985229 0.08 0.07 5.9e-03 0.02 0.02 -0 -0 9.6e-02 7.7e-02 4.1e-01 4.7e-01
4 PL gene expression LOC108352124 0.16 0.07 0.0e+00 0.21 0.23 0.22 0.22 1.3e-22 8.0e-25 2.6e-23 7.8e-24
5 BLA gene expression LOC108352124 0.25 0.07 0.0e+00 0.29 0.34 0.33 0.33 5.5e-16 1.4e-18 3.9e-18 2.5e-18
6 RMTg gene expression LOC108352124 0.14 0.1 1.0e-03 0.05 0.06 0.04 0.07 1.6e-02 1.0e-02 3.2e-02 7.7e-03
7 pVTA gene expression LOC108352124 0.07 0.05 2.6e-04 0.07 0.08 0.08 0.09 3.8e-04 3.4e-04 1.9e-04 1.5e-04
8 Brain gene expression LOC108352124 0.1 0.06 3.4e-13 0.15 0.14 0.14 0.14 8.9e-14 3.6e-13 2.8e-13 4.6e-13
9 IL gene expression LOC108352124 0.37 0.19 2.5e-04 0.12 0.12 0.17 0.11 1.1e-03 1.1e-03 8.4e-05 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.62.63.2-1.41.71.61.81.51.71.7-1.6-1.6
Area under the delay curve0.20.30.50.6-0.6-0.5-0.3-0.5-0.7-0.50.5-0.2
BMI with tail11.135.939.9-6.35.86.05.86.35.76.1-6.0-5.8
BMI without tail1.42.94.6-1.81.41.61.71.81.31.8-1.8-2.1
Body weight0.31.33.6-1.4-0.20.70.61.5-0.51.1-1.3-1.9
Weight adjusted by age0.91.01.20.7-1.1-1.0-1.0-0.9-1.1-1.11.11.0
Bone surface0.30.50.8-0.50.50.60.70.70.50.9-0.9-0.9
Bone volume1.11.92.4-1.21.21.31.41.41.21.5-1.5-1.5
Breakpoint value in progressive ratio session4.44.86.32.3-1.9-2.4-2.4-2.3-1.9-2.22.51.6
Number of licking bursts0.10.10.20.3-0.0-0.2-0.2-0.30.0-0.30.30.4
Context. condit. distance diff. score0.20.30.5-0.50.50.40.40.60.50.6-0.7-0.5
Locomotion velocity, session 10.40.40.6-0.80.60.70.60.80.60.6-0.4-0.6
Locomotion distance, session 13.03.85.31.7-2.3-1.9-2.0-1.7-2.3-2.01.81.7
Locomotion velocity, session 21.01.22.20.9-1.4-1.1-1.0-0.9-1.5-1.01.10.5
Locomotion distance, session 23.44.76.42.0-2.5-2.1-2.1-2.0-2.5-2.22.11.9
Locomotion velocity, session 30.10.10.30.1-0.5-0.2-0.2-0.2-0.5-0.30.20.1
Locomotion distance, session 33.53.85.11.9-2.2-2.0-1.9-1.8-2.3-1.91.91.7
Stereotopy head waving bouts, day 34.95.76.7-2.32.52.42.62.22.42.3-2.3-2.4
Stereotopy head waving duration, day 33.34.04.8-2.11.92.02.12.01.91.9-1.9-2.2
Locomotion velocity, session 71.71.82.61.2-1.6-1.3-1.3-1.3-1.6-1.31.31.1
Locomotion distance, session 75.26.67.82.6-2.8-2.6-2.5-2.5-2.8-2.42.52.3
Stereotopy head waving bouts, day 70.70.81.4-0.91.20.90.90.81.20.8-0.7-0.8
Stereotopy head waving duration, day 70.30.40.8-0.60.80.60.50.50.90.4-0.3-0.5
Locomotion velocity, session 80.00.00.1-0.3-0.1-0.0-0.20.4-0.10.2-0.2-0.2
Locomotion distance, session 80.81.11.91.0-1.4-1.1-1.1-0.8-1.4-1.00.80.8
Degree of sensitization distance0.00.00.00.0-0.2-0.1-0.1-0.1-0.2-0.10.1-0.0
Degree of sensitization stereotypy0.10.10.20.20.4-0.1-0.1-0.30.5-0.20.30.4
Conditioned locomotion1.01.21.6-1.00.91.11.21.10.81.2-1.2-1.2
Cocaine response after cond. corrected6.37.19.2-2.42.42.62.82.62.32.9-2.8-3.0
Cocaine response after cond. not corrected3.74.16.1-1.81.72.02.32.01.52.2-2.1-2.5
Cocaine response before conditioning2.32.73.11.7-1.7-1.6-1.5-1.7-1.6-1.71.81.6
Saline control response0.20.30.40.6-0.4-0.4-0.4-0.6-0.3-0.60.50.6
Bone: connectivity density0.20.30.7-0.20.80.50.60.30.80.6-0.5-0.3
Bone: cortical apparent density5.57.310.03.0-1.9-2.6-2.6-3.0-1.8-2.83.03.2
Bone: cortical area0.00.00.1-0.1-0.10.20.30.2-0.10.1-0.2-0.3
Bone: cortical porosity0.50.50.8-0.80.60.80.90.70.60.8-0.7-0.6
Bone: cortical porosity0.40.40.8-0.70.40.80.90.60.40.6-0.6-0.6
Bone: cortical thickness0.20.40.60.8-0.7-0.5-0.4-0.6-0.8-0.70.70.4
Bone: cortical thickness1.01.22.01.4-1.3-1.0-0.6-1.2-1.3-1.01.10.7
Bone: cortical tissue density5.87.610.53.1-2.0-2.7-2.6-3.1-1.8-2.83.03.2
Condit. Reinf. active minus inactive responses0.10.10.10.3-0.0-0.3-0.2-0.30.0-0.20.30.3
Condit. Reinf. active-inactive response ratio0.30.40.7-0.50.80.60.60.50.80.5-0.3-0.6
Condit. Reinf. active responses0.00.10.20.40.1-0.2-0.1-0.30.1-0.10.20.4
Condit. Reinf. inactive responses0.30.40.90.8-0.3-0.5-0.5-0.7-0.3-0.50.51.0
Incentive salience index mean0.20.20.30.5-0.2-0.4-0.3-0.6-0.2-0.50.60.6
Condit. Reinf. lever presses0.71.01.61.0-0.7-0.9-0.9-1.1-0.7-1.11.11.3
Condit. Reinf. active minus inactive responses0.10.20.3-0.50.30.50.60.40.40.3-0.4-0.2
Condit. Reinf. active-inactive response ratio0.50.50.8-0.70.80.80.80.60.90.6-0.7-0.3
Condit. Reinf. active responses0.00.00.1-0.10.10.20.30.00.20.0-0.10.2
Condit. Reinf. inactive responses0.20.20.40.5-0.3-0.4-0.2-0.6-0.3-0.60.60.6
Condit. Reinf. lever presses0.60.91.00.9-1.0-0.8-0.8-0.9-0.9-1.00.91.0
Condit. Reinf. lever reinforcers received0.00.00.10.2-0.2-0.00.1-0.2-0.1-0.20.10.4
Conditioned reinforcement - actives1.61.62.1-1.31.41.41.51.21.41.2-1.2-0.9
Conditioned reinforcement - inactives0.60.71.50.9-0.6-0.6-0.6-1.0-0.4-1.00.81.2
Conditioned locomotion4.75.77.2-2.52.32.62.72.42.32.2-2.3-2.1
Patch foraging indifference point 0 sec1.11.82.5-1.31.21.41.61.31.11.3-1.3-1.6
Patch foraging indifference point AUC0.20.20.40.4-0.1-0.5-0.6-0.4-0.0-0.40.40.6
Delay disc. indifference point, 0s delay0.91.01.61.1-0.8-1.0-0.9-1.2-0.8-1.11.30.6
Delay disc. indifference point, 16s delay0.30.30.7-0.40.20.50.70.60.10.6-0.7-0.9
Delay disc. indifference point, 2s delay0.30.30.60.3-0.8-0.4-0.2-0.6-0.8-0.70.8-0.0
Delay disc. indifference point, 24s delay0.40.30.60.7-0.8-0.6-0.5-0.5-0.8-0.40.30.3
Delay disc. indifference point, 4s delay3.53.64.92.0-2.1-2.0-1.8-2.0-2.2-1.92.00.8
Delay disc. indifference point, 8s delay0.00.10.20.4-0.2-0.2-0.1-0.3-0.2-0.10.1-0.2
Indifference point function ln k0.00.00.1-0.0-0.20.10.30.2-0.30.2-0.3-0.1
Indifference point function log k0.00.00.1-0.0-0.20.10.30.2-0.30.2-0.3-0.1
Patch foraging total patch changes 0 sec1.11.72.8-1.31.11.31.51.31.01.3-1.3-1.7
Patch foraging total patch changes 12 sec0.40.50.9-0.50.90.70.90.51.00.7-0.7-0.5
Patch foraging total patch changes 18 sec1.41.82.2-1.41.41.51.41.31.51.3-1.3-1.0
Patch foraging total patch changes 24 sec1.82.23.4-1.41.61.41.51.41.51.4-1.2-1.8
Patch foraging total patch changes 6 sec1.01.51.9-1.21.31.31.41.21.31.2-1.3-1.0
Patch foraging time to switch 0 sec0.10.10.3-0.40.50.40.40.30.50.3-0.3-0.2
Patch foraging water rate 0 sec0.60.92.1-0.90.50.91.01.00.41.0-1.1-1.5
Patch foraging water rate 12 sec0.20.30.90.3-0.9-0.5-0.4-0.3-0.9-0.40.30.2
Patch foraging water rate 18 sec0.60.81.30.9-1.1-0.8-0.7-0.9-1.1-0.90.90.3
Patch foraging water rate 24 sec0.50.71.0-0.80.60.91.00.80.50.9-0.9-1.0
Patch foraging water rate 6 sec0.00.10.10.3-0.2-0.2-0.2-0.3-0.1-0.30.30.2
Seeking ratio, delayed vs. immediate footshock0.20.20.5-0.30.40.50.50.60.40.7-0.60.0
Distance traveled before self-admin0.40.50.70.7-0.6-0.7-0.7-0.8-0.6-0.90.80.3
Distance traveled after self-admin1.51.62.5-1.31.21.21.11.41.11.4-1.3-1.6
Extensor digitorum longus weight0.10.30.5-0.6-0.70.0-0.30.7-0.70.4-0.6-0.3
Bone: elastic displacement0.20.20.4-0.60.30.50.50.50.20.3-0.3-0.5
Bone: elastic work0.00.10.2-0.1-0.40.10.20.2-0.40.1-0.2-0.2
Bone: endosteal estimation0.30.61.1-0.80.30.60.61.00.21.0-1.0-1.0
Bone: endosteal perimeter0.40.81.2-1.00.70.80.71.10.61.0-1.1-1.1
Epididymis fat weight0.00.10.3-0.2-0.6-0.00.00.1-0.6-0.10.20.1
Delta time in closed arm before/after self-admin0.10.10.20.10.3-0.3-0.4-0.10.2-0.00.2-0.1
Delta time in open arm before/after self-admin0.20.20.40.3-0.4-0.4-0.5-0.5-0.3-0.50.30.6
Diff in mean of infusions in LGA sessions0.70.71.51.1-0.1-0.9-0.9-0.90.0-0.81.20.9
Delay discount exponential model param0.30.30.7-0.60.80.60.40.60.80.5-0.50.2
Extinction: sum of active levers before priming0.80.81.10.9-0.9-1.0-1.0-0.9-1.0-0.80.90.5
Active lever presses in extinction session 60.20.20.3-0.30.60.40.40.40.50.4-0.3-0.5
Bone: final force0.20.30.7-0.40.30.70.90.60.30.6-0.6-0.5
Bone: final moment0.20.40.8-0.50.30.70.90.70.30.6-0.7-0.7
Food consumed during 24 hour testing period1.41.62.11.3-1.2-1.4-1.5-1.2-1.2-1.21.21.3
Glucose0.40.61.1-0.70.20.81.00.80.20.8-0.8-1.1
Heart weight0.91.32.4-1.20.91.00.91.30.81.0-1.2-1.5
Delay discount hyperbolic model param0.60.61.0-0.81.00.80.60.81.00.7-0.80.0
Intermittent access intake day 1-15 change2.12.02.8-1.71.21.61.61.51.11.4-1.4-1.4
Intermittent access intake escalation2.22.23.0-1.71.31.61.61.61.21.4-1.5-1.4
Intermittent access intake escalation 21.41.42.0-1.41.01.31.21.30.91.1-1.3-1.1
Intermitt. access day 1 inactive lever presses0.40.41.00.8-0.5-0.5-0.5-0.8-0.4-0.70.61.0
Intermitt. access day 15 inactive lever presses0.40.51.5-0.21.10.70.60.31.20.4-0.50.1
Intermitt. access escalation Index3.12.73.4-1.41.81.41.41.61.61.8-1.7-1.8
Intermittent access day 1 total infusions0.10.20.40.6-0.1-0.4-0.3-0.5-0.1-0.30.20.5
Intermittent access day 15 total infusions0.30.40.5-0.50.70.60.70.50.60.6-0.6-0.5
Intermittent access terminal intake (last 3 days)0.30.30.6-0.40.80.50.50.40.80.5-0.5-0.4
Intermittent access total infusions0.00.10.1-0.00.40.20.20.10.30.2-0.2-0.2
Intermittent access day 1 locomotion0.10.10.20.5-0.2-0.3-0.2-0.4-0.2-0.40.30.3
Intermittent access day 15 total locomotion0.30.40.5-0.50.60.70.70.60.60.5-0.6-0.6
Intermittent access total locomotion0.80.91.2-0.81.01.01.10.90.90.9-1.0-0.9
Intermittent access standard deviation1.71.82.4-1.31.31.41.41.31.21.2-1.4-1.5
Left kidney weight0.20.72.70.4-1.5-0.7-0.5-0.0-1.6-0.30.0-0.7
Right kidney weight0.20.71.9-0.8-0.30.60.81.0-0.40.8-1.0-1.4
Cocaine induced anxiety0.00.00.1-0.10.20.1-0.10.30.20.1-0.3-0.3
Post-drug Anxiety0.60.61.21.0-0.3-0.7-0.9-0.8-0.2-0.90.81.1
Baseline Anxiety0.20.21.00.20.20.10.1-0.30.4-0.30.31.0
Tail length10.431.644.25.4-6.5-5.9-5.5-5.4-6.6-5.45.34.1
Length with tail7.828.446.04.9-6.6-5.5-5.3-4.7-6.8-5.04.73.7
Length without tail0.61.33.30.8-1.8-1.1-1.2-0.6-1.8-0.90.80.8
Times rat made contact with spout0.00.00.10.20.1-0.1-0.1-0.20.2-0.10.20.2
Lifetime Intake0.00.00.10.20.2-0.00.0-0.00.20.0-0.1-0.0
Liver weight, left0.91.51.71.2-1.2-1.2-1.2-1.2-1.2-1.31.21.1
Liver weight, right1.52.44.51.6-2.0-1.5-1.3-1.4-2.1-1.51.40.9
Locomotor activity0.81.32.3-0.91.51.11.10.91.51.1-1.0-0.9
Locomotor testing distance1.62.65.0-1.32.11.71.71.22.21.5-1.4-1.0
Locomotor testing rearing0.20.31.2-0.11.00.50.50.01.10.2-0.10.1
Locomotion in novel chamber0.60.71.21.1-0.5-0.9-0.7-1.0-0.5-0.91.10.6
Locomotion in novel chamber post-restriction2.02.43.3-1.71.81.61.51.41.81.4-1.5-0.9
Fecal boli incidents, locomotor time 12.32.53.2-1.71.51.61.51.71.41.7-1.8-1.3
Change in fecal boli incidents, locomotor task2.01.92.31.4-1.4-1.5-1.4-1.5-1.4-1.41.41.1
Time >=10cm from walls, locomotor time 10.10.10.20.50.1-0.3-0.2-0.40.1-0.20.30.1
Bouts of movement, locomotor time 10.10.10.3-0.1-0.50.10.10.3-0.40.2-0.40.0
Total resting periods, locomotor time 10.10.10.3-0.3-0.50.20.30.4-0.50.4-0.6-0.1
Rest time, locomotor task time 10.20.20.4-0.6-0.10.40.50.5-0.10.4-0.7-0.3
Distance moved, locomotor task time 10.60.71.11.1-0.4-1.0-0.9-1.0-0.5-0.81.00.3
Vertical activity count, locomotor time 10.10.10.20.3-0.0-0.4-0.4-0.40.0-0.10.40.0
Time >=10cm from walls, locomotor time 20.50.50.70.7-0.8-0.6-0.5-0.8-0.7-0.80.80.8
Bouts of movement, locomotor time 20.10.10.2-0.30.20.30.40.30.20.3-0.4-0.2
Total resting periods, locomotor time 20.10.10.2-0.30.30.40.40.30.30.4-0.5-0.2
Rest time, locomotor task time 21.11.32.01.3-0.8-1.2-1.4-1.2-0.7-1.10.91.4
Distance moved, locomotor task time 20.10.20.50.1-0.6-0.3-0.1-0.2-0.7-0.20.4-0.6
Vertical activity count, locomotor time 20.30.31.2-0.7-0.10.30.50.5-0.20.5-0.3-1.1
Light reinforcement 10.50.92.1-0.71.31.11.10.71.40.8-0.7-0.4
Light reinforcement 20.10.10.3-0.30.50.30.40.20.60.4-0.3-0.2
Bone: marrow area0.20.40.8-0.70.20.50.40.80.10.8-0.9-0.9
Bone: maximum diameter0.40.70.9-0.80.80.90.90.90.70.9-0.9-0.9
Bone: maximum force0.50.81.3-0.70.40.91.11.10.41.0-1.1-1.0
Bone: maximum moment0.50.91.3-0.80.41.01.11.10.31.1-1.1-1.2
Mean time between licks in bursts0.10.10.2-0.40.20.20.10.40.20.4-0.4-0.3
Mean num. licks in bursts0.00.00.10.2-0.2-0.2-0.2-0.2-0.2-0.20.20.1
Cd content in liver0.50.60.80.8-0.6-0.8-0.8-0.9-0.5-0.80.80.8
Co content in liver0.00.00.0-0.10.0-0.0-0.10.20.00.2-0.2-0.2
Cu content in liver1.92.33.51.5-1.2-1.6-1.7-1.5-1.2-1.41.51.9
Fe content in liver1.72.13.01.4-1.7-1.5-1.5-1.3-1.7-1.31.31.2
K content in liver0.10.10.3-0.40.20.30.40.30.20.4-0.3-0.5
Mg content in liver0.70.71.00.9-0.7-0.8-0.8-0.9-0.7-0.90.91.0
Mn content in liver2.02.33.61.5-1.0-1.5-1.6-1.7-0.9-1.61.71.9
Na content in liver1.01.01.5-0.91.21.01.00.91.20.9-0.8-0.9
Rb content in liver0.20.21.10.4-0.1-0.1-0.1-0.40.1-0.40.31.1
Se content in liver0.20.20.3-0.40.40.40.60.30.50.3-0.3-0.5
Sr content in liver1.71.52.01.0-1.4-1.3-1.3-1.2-1.4-1.31.30.8
Zn content in liver0.10.10.2-0.30.40.30.30.10.40.00.00.0
Bone: minimum diameter0.00.10.2-0.2-0.20.10.20.3-0.40.3-0.3-0.4
Time in familiar zone, hab. session 10.50.41.10.8-0.0-0.6-0.6-0.80.0-0.60.71.0
Time in novel zone, hab. session 13.13.03.5-1.91.51.81.91.71.51.7-1.8-1.9
Total zone transitions, hab. session 16.99.710.63.1-3.1-3.1-3.3-3.0-3.1-3.13.03.1
Total locomotion distance, hab. session 12.73.94.52.1-1.9-1.9-1.9-2.0-1.8-2.11.82.1
Locomotion velocity, hab. session 13.85.46.02.4-2.4-2.3-2.3-2.2-2.4-2.42.22.3
Time in familiar zone, hab. session 20.40.40.9-0.60.90.70.60.50.90.5-0.4-0.3
Time in novel zone, hab. session 20.10.10.20.2-0.4-0.2-0.1-0.2-0.5-0.1-0.00.0
Total zone transitions, hab. session 21.82.32.81.5-1.4-1.5-1.6-1.5-1.3-1.51.51.7
Total locomotion distance, hab. session 20.00.00.10.1-0.3-0.1-0.1-0.1-0.2-0.30.10.3
Locomotion velocity, hab. session 20.10.10.20.2-0.5-0.2-0.2-0.2-0.5-0.40.20.3
Novel to familiar place preference ratio0.91.01.51.0-1.2-1.1-1.1-0.9-1.2-0.70.80.6
Novelty place preference1.11.11.61.1-1.2-1.2-1.1-0.9-1.3-0.70.90.7
Time in novel zone, NPP test0.80.81.11.0-1.0-1.0-1.0-0.9-1.1-0.60.70.6
Total zone transitions, NPP test3.85.36.42.1-2.4-2.2-2.3-2.2-2.4-2.52.32.3
Total locomotion distance, NPP test1.01.32.01.0-1.3-1.0-1.0-1.1-1.2-1.41.11.2
Locomotion velocity, NPP test1.62.33.11.3-1.8-1.4-1.4-1.4-1.7-1.71.41.4
Intraocular pressure1.11.52.01.4-1.3-1.4-1.4-1.1-1.4-0.80.90.9
Delta distance traveled before/after self-admin2.72.93.9-1.81.61.71.61.91.52.0-1.9-1.4
Delta ambulatory time before/after self-admin2.83.13.9-1.91.41.81.81.91.42.0-1.9-1.5
Parametrial fat weight0.10.20.3-0.00.40.30.50.20.50.6-0.5-0.3
Pavlov. Cond. lever latency1.21.62.3-1.21.01.11.01.50.81.5-1.5-1.5
Pavlov. Cond. magazine entry latency0.10.10.40.10.60.30.6-0.10.60.1-0.10.0
Pavlov. Cond. change in total contacts1.61.72.71.6-0.7-1.2-1.0-1.6-0.6-1.41.51.6
Pavlov. Cond. index score0.30.40.80.7-0.1-0.4-0.2-0.80.1-0.70.80.9
Pavlov. Cond. latency score0.40.50.90.8-0.3-0.5-0.3-0.9-0.2-0.90.90.9
Pavlov. Cond. lever contacts1.61.92.91.4-1.0-1.2-1.2-1.6-0.9-1.51.61.7
Pavlov. Cond. magazine entry number0.20.20.5-0.5-0.4-0.0-0.20.5-0.60.3-0.4-0.7
Pavlov. Cond. intertrial magazine entries0.60.81.00.8-1.0-1.0-1.0-0.8-1.0-0.70.70.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.6-0.0-0.3-0.1-0.80.1-0.60.70.8
Pavlov. Cond. response bias0.30.41.10.8-0.0-0.3-0.2-0.90.1-0.70.81.0
Pavlov. Cond. lever latency0.50.70.90.9-0.8-0.9-0.9-0.8-0.9-0.80.80.8
Pavlov. Cond. magazine entry latency0.50.61.00.7-1.0-0.7-0.7-0.7-1.0-0.70.80.4
Pavlov. Cond. change in total contacts0.20.30.5-0.50.40.60.70.50.50.5-0.6-0.5
Pavlov. Cond. index score0.20.30.6-0.60.30.60.70.60.30.5-0.5-0.8
Pavlov. Cond. latency score0.10.10.4-0.40.00.40.50.40.00.3-0.3-0.6
Pavlov. Cond. lever contacts0.50.70.9-0.80.80.91.00.80.80.7-0.8-0.9
Pavlov. Cond. magazine entry number0.00.00.10.10.3-0.1-0.2-0.10.3-0.10.10.4
Pavlov. Cond. intertrial magazine entries2.02.74.01.6-1.5-1.7-1.8-1.6-1.4-1.61.62.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.70.30.70.70.70.30.6-0.6-0.9
Pavlov. Cond. response bias0.50.71.0-0.80.60.91.00.80.70.7-0.8-0.9
Time in closed arm before self-admin0.60.71.2-1.00.61.11.10.80.60.6-0.7-0.6
Time in closed arm after self-admin0.30.30.5-0.70.60.60.50.70.50.5-0.5-0.7
Time in open arm before self-admin0.10.10.30.4-0.0-0.4-0.5-0.2-0.1-0.10.20.4
Time in open arm after self-admin0.40.41.30.5-0.3-0.6-0.7-0.6-0.3-0.60.51.1
Bone: periosteal estimation0.30.60.9-0.70.50.70.80.90.40.9-1.0-1.0
Bone: periosteal perimeter0.30.40.9-0.70.40.60.60.80.30.7-0.7-0.9
Bone: post-yield work0.10.20.4-0.10.20.20.30.50.10.6-0.7-0.4
Progressive ratio test 1 active lever presses0.00.00.00.2-0.0-0.10.1-0.2-0.1-0.10.1-0.1
Progressive ratio test 1 breakpoint0.10.10.20.4-0.4-0.3-0.1-0.4-0.4-0.30.30.1
Progressive ratio test 1 inactive lever presses0.10.10.2-0.10.40.30.40.20.40.2-0.3-0.2
Progressive ratio test 2 active lever presses0.00.00.10.20.1-0.00.1-0.20.2-0.10.10.2
Progressive ratio test 2 breakpoint0.00.00.00.10.20.10.2-0.10.2-0.0-0.00.1
Progressive ratio test 2 inactive lever presses0.10.10.20.50.1-0.3-0.4-0.40.1-0.40.30.5
Incentive Sensitization - Responses0.00.00.1-0.10.20.30.30.10.30.1-0.1-0.0
Incentive Sensitization - Breakpoint0.20.20.3-0.30.40.50.50.30.40.3-0.4-0.3
Sum of active levers in priming session hrs 5-63.13.04.62.0-1.3-1.8-1.7-1.9-1.3-1.92.11.3
Progressive ratio0.40.51.10.5-0.5-0.6-0.7-0.7-0.5-1.01.00.3
Food seeking constrained by brief footshock0.60.81.1-0.60.90.91.00.90.91.0-0.9-0.8
Seeking ratio, punishment vs. effort0.60.71.8-0.40.80.80.90.80.81.3-1.2-0.5
Retroperitoneal fat weight0.30.91.4-1.10.00.91.21.2-0.10.9-1.1-1.2
Reaction time number correct0.30.40.60.5-0.8-0.5-0.6-0.5-0.7-0.60.50.6
Reaction time mean minus median0.20.31.20.7-0.2-0.5-0.6-0.6-0.0-0.40.31.1
Reaction time mean minus median AUC0.40.51.80.8-0.1-0.5-0.6-0.70.0-0.50.51.4
Reaction time num false alarms0.20.20.40.4-0.4-0.4-0.3-0.5-0.3-0.50.60.6
Reaction time num false alarms AUC0.20.30.40.5-0.5-0.5-0.4-0.6-0.5-0.60.70.6
Reaction time trials correct on left0.30.40.60.5-0.8-0.5-0.6-0.5-0.7-0.60.50.6
Reaction time trials on left0.30.40.60.6-0.8-0.5-0.6-0.5-0.7-0.60.50.6
Reaction time mean0.20.30.9-0.20.80.30.20.30.90.5-0.60.3
Reaction time mean AUC0.20.20.7-0.10.70.30.20.20.90.5-0.50.4
Median of all reaction times0.50.71.8-0.61.20.70.70.61.30.8-0.8-0.2
Reaction time omissions0.00.00.10.20.20.10.20.10.30.3-0.30.2
Reaction time false alarm rate0.00.00.0-0.00.0-0.00.1-0.20.0-0.10.20.1
Reaction time premature initiation rate0.20.30.40.4-0.6-0.5-0.4-0.6-0.6-0.50.60.5
Reaction time premature initiations0.60.91.20.8-1.1-0.9-0.9-0.9-1.1-1.01.00.9
Std. dev. reaction times0.10.10.70.5-0.0-0.3-0.3-0.30.1-0.20.10.8
Reaction time trials completed0.30.40.60.6-0.8-0.5-0.6-0.5-0.7-0.60.50.6
Reaction time trials AUC0.30.40.60.6-0.8-0.5-0.7-0.5-0.7-0.60.60.7
Run reversals in cocaine runway, females0.10.10.20.3-0.2-0.4-0.4-0.2-0.4-0.10.3-0.3
Run reversals in cocaine runway, males0.90.92.2-0.91.31.10.90.81.50.6-0.70.0
Latency to leave start box in cocaine runway1.92.02.7-1.61.31.41.21.61.21.5-1.5-1.4
Latency to leave start box in cocaine runway, F3.23.54.6-2.11.61.91.82.11.41.9-2.1-1.9
Latency to leave start box in cocaine runway, M0.50.50.7-0.60.80.60.50.80.80.8-0.6-0.6
Std. dev. time between licks in bursts1.21.41.6-1.31.21.21.11.21.21.2-1.3-1.1
Total sessions with >9 infusions0.50.60.9-0.80.70.80.90.70.60.8-0.9-0.6
Short access day 1 total inactive lever presses3.33.75.12.3-1.3-1.9-1.8-2.2-1.2-2.12.12.1
Short access day 10 total inactive lever presses1.11.32.41.2-0.9-1.0-1.2-1.1-0.7-1.21.11.5
Short access day 1 total infusions0.00.00.10.20.3-0.1-0.1-0.10.3-0.1-0.00.3
Short access day 10 total infusions0.40.50.7-0.60.80.60.60.60.70.7-0.7-0.8
Short access total infusions0.00.00.1-0.10.30.10.10.10.20.1-0.3-0.3
Short access day 1 locomotion0.80.91.3-0.90.91.01.10.90.90.8-0.9-1.0
Short access day 10 total locomotion0.40.50.9-0.60.40.81.00.70.30.4-0.6-1.0
Short access total locomotion0.80.81.2-0.90.61.01.10.90.50.7-0.9-1.1
One hour access (0.3 mA shock)0.40.50.80.8-0.4-0.8-0.7-0.8-0.4-0.70.90.8
Compulsive drug intake6.66.77.82.7-2.3-2.7-2.7-2.7-2.2-2.62.82.4
One hour access (shock baseline)2.42.83.1-1.71.71.81.81.71.71.7-1.7-1.5
Social response proportion0.70.71.40.8-1.1-0.9-0.7-0.8-1.2-0.80.60.4
Social responses0.00.00.00.2-0.1-0.1-0.0-0.1-0.1-0.1-0.0-0.1
Social time0.10.10.50.10.60.1-0.00.00.70.10.00.2
Soleus weight0.92.63.8-1.71.21.82.01.71.21.5-1.6-1.8
Bone: stiffness0.00.10.20.0-0.10.20.40.3-0.10.4-0.4-0.2
Tibialis anterior weight0.41.22.10.9-1.5-1.1-1.2-0.8-1.4-1.00.91.1
Time to tail flick, vehicle, before self-admin1.81.83.51.9-0.7-1.4-1.5-1.5-0.8-1.21.41.4
Time to tail flick, vehicle, after self-admin0.10.20.4-0.20.60.30.30.30.60.4-0.3-0.4
Time to tail flick, test, before self-admin0.00.00.00.00.10.0-0.10.10.10.1-0.2-0.2
Time to tail flick, test, after self-admin0.10.10.3-0.20.30.30.30.40.20.5-0.4-0.5
Delta time to tail flick, vehicle, before/after SA1.41.41.7-1.31.01.21.31.21.11.1-1.2-1.1
Delta time to tail flick, test, before/after SA0.10.10.20.2-0.3-0.2-0.0-0.3-0.4-0.20.4-0.0
Tibia length0.20.71.2-0.90.10.80.81.1-0.00.9-1.1-1.0
Ambulatory time before self-admin0.30.30.40.4-0.5-0.5-0.5-0.5-0.5-0.70.60.4
Ambulatory time after self-admin1.92.02.9-1.71.01.31.31.60.81.6-1.5-1.7
Bone: tissue strength0.10.10.2-0.40.30.30.20.40.30.3-0.4-0.2
Total heroin consumption1.61.93.01.7-0.8-1.4-1.4-1.4-0.7-1.31.51.6
Bone: trabecular number0.81.32.1-0.81.41.21.30.91.41.0-1.0-0.8
Bone: trabecular spacing0.00.10.1-0.1-0.2-0.1-0.3-0.1-0.2-0.40.30.4
Bone: trabecular thickness1.51.83.1-1.31.01.31.41.40.91.4-1.3-1.7
Bone: trabecular tissue density0.20.20.50.3-0.6-0.3-0.3-0.4-0.5-0.70.60.4
Water consumed over 24 hours0.20.20.40.6-0.3-0.5-0.5-0.5-0.2-0.50.50.6
Number of responses in last shaping day0.00.00.1-0.00.30.10.00.10.30.2-0.30.0