Hub : Genes

LOC108351929

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA XR_010054975.1 0.16 0.07 0.0e+00 0.17 0.17 0.18 0.18 4.9e-19 8.1e-19 4.0e-19 1.3e-19
2 Adipose mRNA stability LOC108351929 0.09 0.07 9.6e-06 0.03 0.03 0.03 0.03 2.0e-04 6.3e-04 9.9e-05 9.8e-05
3 Adipose gene expression LOC108351929 0.24 0.1 0.0e+00 0.12 0.15 0.15 0.14 9.9e-13 4.2e-16 5.2e-16 1.8e-15
4 Adipose isoform ratio XR_010054975.1 0.19 0.09 0.0e+00 0.16 0.17 0.18 0.17 4.6e-17 8.8e-19 2.2e-19 6.3e-19
5 Adipose alternative polyA XR_010054974.1 0.56 0.11 0.0e+00 0.33 0.33 0.34 0.35 1.1e-37 1.1e-37 3.4e-39 2.1e-40
6 Adipose isoform ratio XR_010054974.1 0.58 0.09 0.0e+00 0.34 0.34 0.35 0.36 2.0e-38 8.3e-39 4.4e-40 4.2e-41
7 Adipose intron excision ratio chr9_58066753_58087344 0.58 0.1 0.0e+00 0.36 0.42 0.42 0.41 8.5e-42 4.0e-50 3.5e-51 1.5e-49
8 Adipose alternative polyA XR_005489138.2 0.44 0.13 4.1e-09 0.09 0.06 0.05 0.08 9.9e-10 9.6e-08 1.3e-06 3.7e-09
9 Adipose intron excision ratio chr9_58031350_58035435 0.29 0.11 1.1e-11 0.12 0.11 0.12 0.12 5.9e-13 3.9e-12 5.5e-13 3.8e-13
10 Adipose isoform ratio XR_005489138.2 0.33 0.14 1.7e-09 0.05 0.07 0.07 0.07 2.0e-06 3.8e-08 1.4e-08 1.2e-08
11 Adipose intron excision ratio chr9_58035722_58036242 0.6 0.06 0.0e+00 0.29 0.32 0.34 0.33 2.6e-32 1.3e-36 2.9e-39 3.9e-37

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.03.11.4-1.4-1.80.9-0.4-0.3-0.0-1.4-0.6-0.5-0.8
Area under the delay curve4.04.77.0-1.91.80.8-2.42.62.61.8-2.1-2.4-2.5-2.2
BMI with tail1.65.714.1-3.63.63.8-3.02.42.31.30.8-0.2-0.60.3
BMI without tail0.30.81.6-1.21.21.2-1.00.90.90.9-0.2-0.3-0.40.2
Body weight0.31.32.81.5-1.6-1.71.6-1.3-1.3-0.40.50.30.60.4
Weight adjusted by age0.10.20.50.3-0.4-0.70.5-0.4-0.40.4-0.3-0.4-0.3-0.1
Bone surface0.81.44.21.0-1.1-2.00.20.40.50.1-1.8-1.2-1.2-1.8
Bone volume0.81.54.31.4-1.4-2.10.7-0.1-0.00.4-1.8-1.1-1.0-1.5
Breakpoint value in progressive ratio session0.10.20.80.1-0.2-0.4-0.00.10.10.8-0.2-0.4-0.2-0.9
Number of licking bursts0.00.00.10.10.20.20.0-0.00.00.1-0.4-0.2-0.00.0
Context. condit. distance diff. score1.51.84.2-1.82.02.1-1.81.41.21.00.3-0.3-0.3-0.3
Locomotion velocity, session 10.70.82.8-1.21.21.7-0.90.50.40.20.80.50.40.8
Locomotion distance, session 10.81.02.5-1.31.31.6-1.00.20.1-0.01.40.90.81.1
Locomotion velocity, session 21.31.53.5-1.81.61.9-1.60.90.9-0.31.30.70.30.7
Locomotion distance, session 21.01.43.6-0.30.10.40.0-0.7-0.7-1.41.91.81.71.6
Locomotion velocity, session 30.70.82.91.1-1.0-0.90.8-0.6-0.5-1.70.20.80.70.1
Locomotion distance, session 30.40.41.20.4-0.3-0.40.6-0.5-0.5-1.10.60.90.80.7
Stereotopy head waving bouts, day 30.30.32.10.2-0.3-0.20.3-0.3-0.2-1.40.30.80.50.4
Stereotopy head waving duration, day 30.60.71.90.6-0.8-0.50.7-0.8-0.7-1.40.51.00.90.6
Locomotion velocity, session 71.71.95.2-1.82.02.3-1.61.31.21.40.2-0.4-0.4-0.3
Locomotion distance, session 70.91.12.9-1.61.71.6-1.10.80.70.60.80.40.30.3
Stereotopy head waving bouts, day 70.20.20.50.7-0.5-0.40.6-0.6-0.6-0.30.10.30.3-0.1
Stereotopy head waving duration, day 70.60.71.71.3-1.1-0.41.2-1.2-1.2-0.40.20.40.60.2
Locomotion velocity, session 80.91.12.8-1.41.51.7-1.30.90.80.80.7-0.4-0.4-0.0
Locomotion distance, session 81.52.25.8-2.22.22.4-1.91.11.00.71.20.40.40.4
Degree of sensitization distance0.50.51.5-1.00.91.1-0.80.50.41.20.0-0.4-0.30.0
Degree of sensitization stereotypy0.10.10.70.3-0.1-0.30.0-0.1-0.00.4-0.4-0.4-0.3-0.8
Conditioned locomotion2.42.85.62.1-2.1-2.42.1-1.9-1.9-1.60.50.70.91.0
Cocaine response after cond. corrected0.10.10.30.3-0.3-0.50.4-0.2-0.30.50.6-0.00.1-0.3
Cocaine response after cond. not corrected0.60.71.61.0-0.9-0.51.3-1.0-1.1-0.00.80.60.80.4
Cocaine response before conditioning0.60.71.20.9-0.70.21.1-1.0-1.0-0.7-0.00.80.91.0
Saline control response0.10.10.2-0.20.30.5-0.1-0.0-0.0-0.2-0.40.20.20.5
Bone: connectivity density0.20.30.90.3-0.3-0.9-0.30.30.40.0-0.8-0.6-0.6-0.8
Bone: cortical apparent density3.54.713.0-3.33.13.6-2.81.71.50.11.70.80.51.3
Bone: cortical area0.10.20.70.2-0.3-0.50.1-0.3-0.3-0.80.40.50.50.3
Bone: cortical porosity2.62.89.02.0-2.0-3.01.3-0.2-0.1-0.1-2.2-1.5-1.4-1.9
Bone: cortical porosity3.74.012.02.3-2.4-3.51.5-0.3-0.1-0.1-2.7-1.9-1.8-2.2
Bone: cortical thickness0.40.71.1-1.00.90.7-1.00.40.3-1.11.00.90.70.8
Bone: cortical thickness0.20.20.6-0.70.80.7-0.50.30.30.00.20.20.20.3
Bone: cortical tissue density3.34.512.4-3.23.13.5-2.71.71.50.11.70.80.41.3
Condit. Reinf. active minus inactive responses2.73.08.72.9-2.7-2.32.3-1.7-1.5-0.6-1.0-0.20.0-0.5
Condit. Reinf. active-inactive response ratio2.22.36.62.6-2.3-1.82.1-1.6-1.5-0.6-0.40.00.20.1
Condit. Reinf. active responses1.41.84.42.1-1.9-1.91.4-0.8-0.70.3-1.3-0.8-0.6-1.3
Condit. Reinf. inactive responses0.50.71.3-0.80.80.2-0.90.90.91.0-0.6-0.7-0.7-1.2
Incentive salience index mean1.72.03.81.8-1.7-2.01.0-0.3-0.20.8-1.9-1.5-1.3-1.8
Condit. Reinf. lever presses1.62.35.1-0.0-0.0-0.8-0.81.31.41.7-1.9-2.1-2.1-2.3
Condit. Reinf. active minus inactive responses1.21.64.31.8-1.7-2.11.6-1.2-1.10.4-1.0-0.4-0.1-0.7
Condit. Reinf. active-inactive response ratio1.41.63.41.5-1.5-1.81.3-0.6-0.51.0-1.7-0.9-0.7-1.3
Condit. Reinf. active responses0.20.20.50.5-0.4-0.70.5-0.6-0.60.5-0.4-0.10.1-0.2
Condit. Reinf. inactive responses0.60.82.3-1.41.51.5-1.10.60.50.60.30.10.10.4
Condit. Reinf. lever presses1.21.73.4-1.11.10.4-1.21.41.41.4-1.8-1.0-1.1-1.7
Condit. Reinf. lever reinforcers received0.10.20.60.3-0.3-0.70.3-0.3-0.30.7-0.8-0.3-0.1-0.4
Conditioned reinforcement - actives0.10.20.90.3-0.4-0.10.3-0.3-0.3-0.90.70.70.50.1
Conditioned reinforcement - inactives0.30.52.10.9-0.9-0.40.6-0.3-0.3-1.40.50.60.6-0.1
Conditioned locomotion0.20.30.7-0.50.50.8-0.40.20.2-0.70.90.60.40.3
Patch foraging indifference point 0 sec4.88.915.5-3.53.21.7-3.93.63.62.7-1.6-2.6-2.9-2.4
Patch foraging indifference point AUC0.10.20.4-0.60.60.5-0.60.40.40.50.2-0.1-0.10.2
Delay disc. indifference point, 0s delay3.53.85.6-1.92.01.4-2.22.42.31.8-1.4-1.9-2.1-1.8
Delay disc. indifference point, 16s delay3.03.24.9-1.31.30.6-1.82.22.21.6-1.9-2.1-2.2-2.0
Delay disc. indifference point, 2s delay2.42.63.4-1.61.50.6-1.81.91.81.8-1.4-1.8-1.8-1.7
Delay disc. indifference point, 24s delay0.80.91.8-0.40.50.1-0.71.11.20.3-1.3-1.2-1.3-1.1
Delay disc. indifference point, 4s delay1.51.52.6-1.51.41.2-1.61.51.50.8-0.8-1.0-1.1-0.8
Delay disc. indifference point, 8s delay3.23.86.3-1.31.20.2-1.82.12.12.1-2.2-2.5-2.5-2.3
Indifference point function ln k1.52.63.4-1.71.70.9-1.81.91.81.7-1.2-1.6-1.7-1.5
Indifference point function log k1.52.63.4-1.71.70.9-1.81.91.81.7-1.2-1.6-1.7-1.5
Patch foraging total patch changes 0 sec4.58.414.5-3.43.11.7-3.83.53.52.7-1.5-2.6-2.8-2.4
Patch foraging total patch changes 12 sec0.91.12.5-1.41.20.6-1.61.41.40.9-0.2-0.8-0.8-0.6
Patch foraging total patch changes 18 sec1.62.45.4-2.32.22.0-2.21.71.60.80.7-0.3-0.5-0.1
Patch foraging total patch changes 24 sec0.81.32.7-1.31.20.2-1.61.51.50.7-0.3-1.0-1.2-1.0
Patch foraging total patch changes 6 sec4.16.311.5-3.02.71.4-3.43.23.12.0-1.1-2.2-2.4-1.9
Patch foraging time to switch 0 sec2.65.26.72.0-2.0-1.02.4-2.6-2.6-2.62.42.42.42.5
Patch foraging water rate 0 sec1.12.33.1-1.71.70.9-1.81.71.71.6-1.3-1.3-1.4-1.5
Patch foraging water rate 12 sec0.81.62.9-1.71.71.1-1.41.31.21.7-0.3-1.0-1.0-0.9
Patch foraging water rate 18 sec0.10.21.0-0.30.30.2-0.20.30.21.0-0.3-0.5-0.3-0.6
Patch foraging water rate 24 sec0.20.30.80.3-0.30.00.7-0.9-0.90.10.00.50.80.5
Patch foraging water rate 6 sec1.31.92.8-1.51.50.7-1.51.61.71.4-1.0-1.3-1.4-1.4
Seeking ratio, delayed vs. immediate footshock1.61.93.71.9-1.9-1.61.8-1.6-1.6-1.00.70.70.90.5
Distance traveled before self-admin1.41.84.22.0-1.8-1.91.4-0.8-0.80.6-1.3-0.9-0.4-1.5
Distance traveled after self-admin1.21.53.60.30.0-0.2-0.30.70.81.9-1.7-1.8-1.4-1.9
Extensor digitorum longus weight1.14.312.3-3.23.13.5-2.71.71.60.20.61.10.81.2
Bone: elastic displacement0.10.10.20.2-0.1-0.20.2-0.4-0.3-0.4-0.40.30.50.3
Bone: elastic work0.60.82.11.2-1.1-1.51.0-1.0-0.9-0.5-0.80.10.30.0
Bone: endosteal estimation1.43.27.72.5-2.4-2.82.0-1.0-0.90.7-1.8-1.4-1.0-1.6
Bone: endosteal perimeter0.91.94.82.1-2.1-2.21.7-1.0-1.00.0-1.2-0.5-0.1-1.0
Epididymis fat weight0.20.82.21.3-1.2-0.61.5-1.2-1.20.30.20.20.50.4
Delta time in closed arm before/after self-admin0.50.51.10.0-0.2-0.8-0.30.60.7-0.2-0.9-0.8-1.0-1.0
Delta time in open arm before/after self-admin2.92.95.42.3-2.2-2.32.2-2.0-2.0-0.90.60.60.70.8
Diff in mean of infusions in LGA sessions0.80.93.50.1-0.1-0.5-0.30.70.71.2-1.3-1.2-1.1-1.9
Delay discount exponential model param3.64.05.81.7-1.7-0.72.2-2.4-2.4-1.71.92.22.32.0
Extinction: sum of active levers before priming0.10.10.30.5-0.5-0.30.3-0.2-0.2-0.10.00.00.2-0.2
Active lever presses in extinction session 60.50.51.30.1-0.2-0.5-0.20.30.31.2-0.9-1.0-0.7-1.0
Bone: final force1.42.25.42.2-2.3-2.31.8-1.4-1.3-0.9-0.60.20.4-0.3
Bone: final moment1.01.73.91.9-2.0-2.01.5-1.3-1.2-0.9-0.40.30.5-0.1
Food consumed during 24 hour testing period0.10.10.50.20.10.70.30.00.10.2-0.5-0.2-0.30.3
Glucose0.50.92.3-0.20.20.70.3-0.7-0.7-1.01.21.31.21.5
Heart weight0.10.20.5-0.40.30.4-0.60.30.20.70.6-0.20.2-0.2
Delay discount hyperbolic model param3.84.26.21.8-1.7-0.72.3-2.5-2.5-1.72.02.32.42.1
Intermittent access intake day 1-15 change0.30.51.1-1.10.90.8-0.90.90.90.50.0-0.3-0.4-0.5
Intermittent access intake escalation0.30.61.3-1.21.00.9-1.00.90.90.30.1-0.1-0.4-0.4
Intermittent access intake escalation 20.80.91.5-0.90.70.3-0.91.21.21.0-0.7-1.0-1.1-1.2
Intermitt. access day 1 inactive lever presses0.20.92.3-1.11.11.5-0.90.90.9-1.10.70.70.30.9
Intermitt. access day 15 inactive lever presses0.51.01.7-1.11.21.2-1.11.31.30.7-0.8-0.7-0.8-0.4
Intermitt. access escalation Index1.31.85.50.3-0.30.50.8-1.2-1.3-1.31.61.71.82.3
Intermittent access day 1 total infusions0.10.20.60.5-0.6-0.70.3-0.3-0.3-0.80.20.30.20.1
Intermittent access day 15 total infusions0.20.31.4-0.30.10.3-0.40.20.2-1.20.90.70.40.3
Intermittent access terminal intake (last 3 days)0.30.30.8-0.70.50.3-0.80.80.9-0.70.30.0-0.4-0.4
Intermittent access total infusions0.40.41.80.4-0.6-0.50.3-0.4-0.4-1.40.80.80.60.3
Intermittent access day 1 locomotion0.10.10.3-0.50.50.4-0.30.20.2-0.20.40.30.10.3
Intermittent access day 15 total locomotion0.40.81.5-1.21.20.9-1.21.11.00.5-0.1-0.3-0.5-0.7
Intermittent access total locomotion0.80.91.9-1.31.41.1-1.31.21.10.3-0.0-0.3-0.5-0.5
Intermittent access standard deviation0.20.30.8-0.80.70.9-0.70.70.70.00.40.1-0.0-0.3
Left kidney weight0.00.20.40.6-0.6-0.30.6-0.4-0.40.5-0.1-0.20.2-0.0
Right kidney weight0.31.33.7-0.70.80.6-0.91.21.21.9-0.6-1.6-1.3-1.1
Cocaine induced anxiety0.40.51.0-0.80.60.5-0.90.80.81.0-0.2-0.6-0.7-0.8
Post-drug Anxiety0.20.20.8-0.60.70.9-0.20.1-0.00.40.50.30.30.2
Baseline Anxiety0.91.11.91.0-0.7-0.31.4-1.4-1.4-0.90.60.91.01.3
Tail length4.116.235.55.7-5.9-6.05.2-4.4-4.3-2.3-0.31.11.70.6
Length with tail4.620.040.46.3-6.4-6.25.9-5.1-5.1-2.60.51.52.31.1
Length without tail1.65.09.83.1-3.1-2.93.1-2.6-2.6-1.10.90.71.10.5
Times rat made contact with spout0.60.72.31.1-0.9-0.91.1-0.7-0.6-1.5-0.00.70.60.3
Lifetime Intake0.40.41.60.1-0.3-0.10.1-0.3-0.3-1.31.11.00.70.6
Liver weight, left2.64.27.42.6-2.7-2.42.5-2.2-2.2-2.21.11.31.51.0
Liver weight, right1.93.45.01.9-1.8-1.52.1-2.2-2.2-1.51.61.61.91.6
Locomotor activity1.52.35.4-0.70.90.5-1.31.51.51.6-2.3-1.9-1.7-1.8
Locomotor testing distance1.73.06.2-1.21.51.1-1.41.61.62.5-2.1-2.1-1.8-1.7
Locomotor testing rearing0.51.12.6-0.91.01.1-0.91.01.01.6-1.1-1.1-0.8-0.8
Locomotion in novel chamber1.51.96.9-1.82.12.6-0.90.40.21.51.30.70.80.9
Locomotion in novel chamber post-restriction0.20.30.90.1-0.2-0.00.3-0.4-0.4-1.00.90.80.60.7
Fecal boli incidents, locomotor time 14.56.611.3-2.01.90.4-2.62.72.73.4-2.5-2.9-2.9-3.0
Change in fecal boli incidents, locomotor task0.50.51.00.7-0.6-0.10.9-1.0-1.00.00.60.60.80.8
Time >=10cm from walls, locomotor time 10.10.10.4-0.1-0.1-0.6-0.30.20.30.2-0.6-0.3-0.3-0.2
Bouts of movement, locomotor time 11.51.73.6-1.91.60.7-1.91.61.61.0-0.3-0.7-0.8-0.9
Total resting periods, locomotor time 11.82.04.4-2.11.91.1-2.01.71.71.1-0.3-0.7-0.9-0.7
Rest time, locomotor task time 10.91.12.2-0.60.5-0.3-1.01.31.40.4-1.2-1.3-1.5-1.1
Distance moved, locomotor task time 10.30.50.80.7-0.8-0.50.8-0.8-0.9-0.30.30.70.90.3
Vertical activity count, locomotor time 10.20.51.10.4-0.40.30.7-0.8-0.8-0.60.81.01.00.7
Time >=10cm from walls, locomotor time 20.40.62.01.1-1.0-1.40.9-0.7-0.70.5-0.3-0.5-0.1-0.3
Bouts of movement, locomotor time 21.32.04.9-2.22.12.1-1.81.51.40.70.9-0.0-0.20.3
Total resting periods, locomotor time 21.42.45.8-2.42.32.2-2.01.61.50.70.9-0.0-0.30.3
Rest time, locomotor task time 20.30.41.7-0.40.30.4-0.20.10.1-1.30.60.50.31.3
Distance moved, locomotor task time 20.10.10.30.3-0.2-0.20.3-0.4-0.40.60.0-0.10.1-0.3
Vertical activity count, locomotor time 20.10.10.4-0.20.30.60.0-0.1-0.10.30.50.00.00.2
Light reinforcement 10.51.23.4-1.81.81.2-1.51.11.1-0.50.30.2-0.20.5
Light reinforcement 20.40.62.1-0.20.2-1.0-0.40.60.8-0.3-1.5-0.8-1.1-0.9
Bone: marrow area1.43.07.32.4-2.3-2.71.9-1.0-0.90.7-1.7-1.4-1.0-1.6
Bone: maximum diameter0.10.20.70.7-0.7-0.80.5-0.3-0.3-0.2-0.10.00.1-0.4
Bone: maximum force1.42.56.22.3-2.4-2.51.9-1.7-1.6-0.9-0.30.30.5-0.1
Bone: maximum moment1.11.84.31.9-2.0-2.11.6-1.5-1.5-0.8-0.10.40.60.1
Mean time between licks in bursts0.51.22.0-1.41.41.4-1.10.40.3-0.61.31.11.11.3
Mean num. licks in bursts0.10.10.30.1-0.3-0.50.10.20.2-0.5-0.30.0-0.3-0.4
Cd content in liver0.30.40.91.0-0.9-0.80.8-0.4-0.40.2-0.4-0.4-0.3-0.6
Co content in liver1.61.93.3-0.70.8-0.1-1.21.61.61.0-1.8-1.7-1.8-1.6
Cu content in liver0.40.51.21.1-1.1-1.10.9-0.6-0.60.3-0.4-0.5-0.4-0.3
Fe content in liver0.81.02.71.3-1.3-1.60.7-0.10.0-0.4-1.3-0.7-0.7-1.0
K content in liver1.21.12.3-0.50.2-0.8-1.11.31.30.0-0.8-1.3-1.5-1.5
Mg content in liver0.20.20.70.1-0.3-0.7-0.20.30.4-0.10.1-0.5-0.6-0.8
Mn content in liver1.01.12.6-1.41.61.6-1.41.01.00.6-0.1-0.2-0.2-0.4
Na content in liver3.03.26.7-0.60.5-0.5-1.31.91.91.7-2.0-2.5-2.6-2.3
Rb content in liver0.20.20.6-0.50.50.4-0.30.10.1-0.50.70.80.70.4
Se content in liver0.10.10.60.1-0.10.0-0.10.20.20.2-0.7-0.1-0.1-0.4
Sr content in liver0.20.20.70.0-0.2-0.8-0.10.00.1-0.7-0.6-0.1-0.30.1
Zn content in liver0.20.20.50.3-0.4-0.70.10.10.10.1-0.3-0.6-0.6-0.7
Bone: minimum diameter0.40.72.21.3-1.3-1.50.9-0.5-0.4-0.2-0.5-0.5-0.4-0.6
Time in familiar zone, hab. session 10.40.41.0-1.01.00.9-0.60.60.50.50.10.0-0.0-0.1
Time in novel zone, hab. session 11.11.12.51.6-1.4-1.61.1-0.6-0.50.4-1.0-0.9-0.7-0.8
Total zone transitions, hab. session 10.30.40.7-0.40.40.1-0.50.60.60.8-0.8-0.8-0.7-0.7
Total locomotion distance, hab. session 10.10.10.30.4-0.3-0.50.4-0.2-0.20.4-0.5-0.2-0.0-0.4
Locomotion velocity, hab. session 10.10.10.50.4-0.4-0.70.3-0.3-0.2-0.2-0.30.10.2-0.2
Time in familiar zone, hab. session 20.20.21.8-0.30.50.6-0.0-0.0-0.11.3-0.2-0.3-0.1-0.1
Time in novel zone, hab. session 20.60.62.60.7-0.9-0.90.6-0.5-0.5-1.60.60.60.40.4
Total zone transitions, hab. session 20.10.20.6-0.20.00.1-0.3-0.1-0.2-0.30.70.60.60.3
Total locomotion distance, hab. session 20.81.11.71.0-1.2-0.91.0-1.3-1.2-0.90.71.21.30.5
Locomotion velocity, hab. session 20.70.91.80.8-0.9-0.60.8-1.1-1.1-0.80.71.31.30.6
Novel to familiar place preference ratio3.53.88.62.6-2.6-2.92.5-2.0-1.8-2.20.30.90.80.8
Novelty place preference3.63.98.12.5-2.5-2.92.5-2.0-1.9-2.40.51.00.91.0
Time in novel zone, NPP test4.34.69.32.7-2.7-3.12.6-2.2-2.1-2.70.61.11.01.0
Total zone transitions, NPP test0.40.51.3-0.90.70.9-0.70.20.1-0.11.10.90.90.6
Total locomotion distance, NPP test0.10.20.60.0-0.1-0.00.1-0.4-0.4-0.00.50.70.80.2
Locomotion velocity, NPP test0.10.10.4-0.30.20.3-0.2-0.0-0.10.20.30.60.60.1
Intraocular pressure1.21.84.7-1.01.12.0-0.1-0.4-0.5-0.12.21.71.51.7
Delta distance traveled before/after self-admin0.60.61.8-1.11.11.3-0.70.30.2-0.00.90.50.40.9
Delta ambulatory time before/after self-admin0.91.12.3-1.51.51.5-1.41.11.00.90.1-0.4-0.50.1
Parametrial fat weight0.20.51.20.1-0.10.70.4-0.6-0.7-0.51.11.11.11.0
Pavlov. Cond. lever latency1.31.64.20.0-0.20.40.5-0.7-0.7-2.11.72.01.71.5
Pavlov. Cond. magazine entry latency0.50.62.70.6-0.5-0.50.6-0.2-0.21.6-0.9-1.0-0.7-0.7
Pavlov. Cond. change in total contacts0.20.21.20.2-0.2-0.10.2-0.2-0.31.10.0-0.4-0.3-0.3
Pavlov. Cond. index score0.50.63.00.3-0.2-0.40.10.10.01.7-0.9-1.2-0.9-0.9
Pavlov. Cond. latency score0.81.04.40.2-0.0-0.4-0.00.30.22.1-1.1-1.5-1.2-1.1
Pavlov. Cond. lever contacts0.60.72.8-0.00.1-0.3-0.30.40.31.7-1.0-1.3-1.1-0.9
Pavlov. Cond. magazine entry number0.60.71.6-1.21.20.8-1.30.90.9-0.90.20.3-0.00.2
Pavlov. Cond. intertrial magazine entries1.11.32.51.5-1.4-1.61.2-1.1-1.0-1.60.10.80.80.1
Pavlov. Cond. lever-magazine prob. diff.0.40.52.70.2-0.2-0.30.10.0-0.01.6-0.7-1.0-0.8-0.8
Pavlov. Cond. response bias0.30.41.20.7-0.6-0.50.5-0.3-0.31.1-0.5-0.7-0.5-0.5
Pavlov. Cond. lever latency0.81.12.00.9-1.0-0.51.0-1.1-1.2-1.21.40.80.81.2
Pavlov. Cond. magazine entry latency0.10.10.40.10.10.2-0.10.10.2-0.4-0.60.20.20.2
Pavlov. Cond. change in total contacts0.61.02.5-0.00.0-0.6-0.40.80.81.1-1.6-1.2-1.1-1.5
Pavlov. Cond. index score0.30.41.6-0.40.50.2-0.60.70.70.6-1.2-0.4-0.3-0.7
Pavlov. Cond. latency score0.20.21.2-0.20.30.1-0.30.50.50.4-1.1-0.2-0.2-0.5
Pavlov. Cond. lever contacts0.81.12.0-0.81.00.5-1.01.21.21.4-1.4-0.9-0.9-1.2
Pavlov. Cond. magazine entry number0.10.10.5-0.40.40.5-0.10.0-0.00.50.7-0.0-0.10.2
Pavlov. Cond. intertrial magazine entries0.40.51.7-0.60.60.80.0-0.3-0.4-0.31.30.80.71.1
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-0.50.50.2-0.60.60.70.5-1.0-0.2-0.2-0.6
Pavlov. Cond. response bias0.20.31.3-0.20.3-0.0-0.30.60.60.5-1.1-0.5-0.4-0.8
Time in closed arm before self-admin0.50.71.51.1-0.9-1.20.7-0.4-0.30.6-1.1-0.9-0.6-0.7
Time in closed arm after self-admin3.03.27.0-0.00.1-1.0-0.81.51.61.7-2.7-2.5-2.5-2.5
Time in open arm before self-admin1.41.63.2-1.11.01.8-0.5-0.2-0.2-1.11.51.81.61.5
Time in open arm after self-admin2.32.54.31.7-1.6-1.11.9-2.1-2.1-1.01.21.41.61.3
Bone: periosteal estimation1.02.06.12.0-2.0-2.51.5-0.8-0.80.0-1.4-0.8-0.5-1.2
Bone: periosteal perimeter0.71.23.41.6-1.6-1.81.3-1.0-1.0-0.5-0.30.10.3-0.4
Bone: post-yield work0.40.61.71.3-1.3-1.11.1-0.7-0.7-0.0-0.4-0.2-0.1-0.3
Progressive ratio test 1 active lever presses0.20.30.7-0.60.40.5-0.60.40.3-0.80.70.50.20.7
Progressive ratio test 1 breakpoint0.20.20.6-0.40.30.3-0.50.30.2-0.70.60.40.20.6
Progressive ratio test 1 inactive lever presses1.21.73.3-1.21.11.8-0.90.30.3-1.41.81.51.21.5
Progressive ratio test 2 active lever presses0.20.31.50.2-0.5-0.40.1-0.0-0.0-1.20.60.60.40.1
Progressive ratio test 2 breakpoint0.20.21.60.2-0.4-0.30.00.00.0-1.30.60.60.30.1
Progressive ratio test 2 inactive lever presses0.30.52.20.5-0.5-0.10.4-0.4-0.4-1.50.81.00.80.5
Incentive Sensitization - Responses0.40.51.31.0-1.2-1.00.9-0.6-0.6-0.80.20.40.4-0.1
Incentive Sensitization - Breakpoint0.40.61.41.0-1.2-0.90.9-0.7-0.6-0.90.20.40.4-0.1
Sum of active levers in priming session hrs 5-60.80.71.71.1-1.1-0.61.3-1.0-1.10.20.40.30.80.2
Progressive ratio0.30.51.20.6-0.4-0.40.8-0.9-0.8-1.00.30.70.51.1
Food seeking constrained by brief footshock0.80.91.81.3-1.4-1.31.2-1.0-1.0-0.80.50.20.10.5
Seeking ratio, punishment vs. effort0.10.10.3-0.1-0.1-0.0-0.30.30.20.50.3-0.3-0.2-0.5
Retroperitoneal fat weight0.20.91.60.4-0.40.60.6-0.9-0.9-0.91.31.21.21.3
Reaction time number correct1.73.37.60.1-0.30.60.7-1.4-1.5-2.52.42.72.62.2
Reaction time mean minus median0.41.12.71.7-1.5-1.61.2-1.0-1.00.1-0.6-0.30.1-0.4
Reaction time mean minus median AUC0.40.92.41.6-1.4-1.51.1-1.0-1.0-0.0-0.5-0.30.1-0.4
Reaction time num false alarms1.41.94.2-2.01.92.0-1.91.71.60.10.30.0-0.40.2
Reaction time num false alarms AUC1.11.73.6-1.81.71.9-1.81.61.6-0.20.30.1-0.30.2
Reaction time trials correct on left1.73.37.60.1-0.30.60.7-1.4-1.5-2.52.42.72.62.2
Reaction time trials on left2.03.78.20.3-0.50.50.9-1.6-1.6-2.62.52.92.72.3
Reaction time mean3.25.212.43.5-3.3-2.53.2-2.7-2.7-0.50.20.61.20.3
Reaction time mean AUC3.04.811.53.4-3.2-2.33.1-2.6-2.6-0.50.30.71.30.4
Median of all reaction times3.85.513.03.6-3.4-2.53.4-2.8-2.8-0.50.30.71.30.4
Reaction time omissions1.21.73.01.7-1.6-1.31.7-1.6-1.5-1.10.20.91.20.7
Reaction time false alarm rate2.02.85.2-1.71.71.4-2.12.22.31.1-1.1-1.4-1.7-1.1
Reaction time premature initiation rate3.54.97.4-1.51.70.7-1.92.32.32.7-2.4-2.7-2.6-2.5
Reaction time premature initiations0.61.11.9-1.31.41.0-1.31.21.11.0-0.7-0.8-0.8-0.9
Std. dev. reaction times1.52.87.22.7-2.5-2.22.3-1.9-1.9-0.1-0.30.00.6-0.2
Reaction time trials completed2.03.78.20.3-0.50.50.9-1.6-1.6-2.62.52.92.72.3
Reaction time trials AUC1.83.58.00.2-0.40.50.8-1.5-1.6-2.52.42.82.72.3
Run reversals in cocaine runway, females1.31.31.91.3-1.2-0.71.4-1.4-1.4-1.10.71.01.11.0
Run reversals in cocaine runway, males1.11.12.0-0.60.70.6-1.11.31.31.1-0.9-1.1-1.0-1.4
Latency to leave start box in cocaine runway2.22.56.4-2.32.32.5-2.11.61.50.40.8-0.1-0.40.6
Latency to leave start box in cocaine runway, F1.61.83.8-1.71.81.9-1.81.61.60.5-0.1-0.6-0.8-0.2
Latency to leave start box in cocaine runway, M2.22.04.9-2.22.12.2-1.50.70.60.21.70.60.41.5
Std. dev. time between licks in bursts1.11.54.0-1.81.61.0-2.01.61.6-0.40.2-0.1-0.40.1
Total sessions with >9 infusions0.70.82.2-1.11.01.2-0.70.20.1-0.61.51.00.71.0
Short access day 1 total inactive lever presses0.40.61.50.2-0.00.50.4-0.6-0.6-1.00.91.00.91.2
Short access day 10 total inactive lever presses0.10.10.4-0.20.30.5-0.20.50.5-0.6-0.20.20.00.0
Short access day 1 total infusions0.50.72.5-0.50.50.9-0.1-0.3-0.4-0.51.61.21.11.0
Short access day 10 total infusions0.10.10.6-0.20.0-0.1-0.30.20.1-0.80.70.50.20.2
Short access total infusions0.20.30.9-0.50.40.4-0.30.10.0-0.51.00.70.50.6
Short access day 1 locomotion0.91.13.9-0.20.00.40.2-0.6-0.7-1.22.01.51.31.4
Short access day 10 total locomotion1.62.94.9-2.02.11.6-2.02.22.21.4-0.9-1.2-1.4-1.1
Short access total locomotion1.01.23.0-1.11.21.7-0.60.20.1-0.71.71.30.91.2
One hour access (0.3 mA shock)0.30.31.00.0-0.2-0.8-0.30.60.6-0.2-0.5-0.5-0.7-1.0
Compulsive drug intake0.20.30.9-0.80.81.0-0.60.40.40.6-0.2-0.1-0.00.1
One hour access (shock baseline)0.30.51.60.9-1.0-1.20.6-0.4-0.4-1.00.20.20.1-0.2
Social response proportion0.60.61.61.1-1.0-1.31.0-0.8-0.80.5-0.6-0.3-0.0-0.3
Social responses0.40.51.5-0.20.1-0.3-0.30.30.31.2-1.1-1.2-0.8-0.6
Social time0.91.22.21.3-1.3-0.91.4-1.4-1.5-0.20.30.71.00.8
Soleus weight0.72.05.5-0.91.01.10.0-0.9-1.0-0.32.31.81.82.3
Bone: stiffness0.81.33.61.7-1.9-1.91.4-1.1-1.1-0.60.1-0.00.1-0.2
Tibialis anterior weight0.51.64.1-2.02.01.8-1.71.21.20.10.10.60.30.6
Time to tail flick, vehicle, before self-admin1.31.43.5-0.60.5-0.3-1.01.41.50.8-1.2-1.3-1.5-1.9
Time to tail flick, vehicle, after self-admin0.70.91.8-0.30.2-0.6-0.61.11.2-0.2-1.3-1.0-1.2-1.3
Time to tail flick, test, before self-admin0.10.20.5-0.30.40.7-0.40.30.3-0.70.20.20.00.2
Time to tail flick, test, after self-admin0.30.31.0-0.50.50.9-0.30.00.0-0.31.00.60.50.7
Delta time to tail flick, vehicle, before/after SA0.20.20.80.1-0.10.10.2-0.3-0.3-0.90.30.50.40.9
Delta time to tail flick, test, before/after SA0.10.10.8-0.20.20.2-0.1-0.1-0.10.90.20.00.2-0.0
Tibia length2.26.112.23.5-3.3-3.13.3-3.1-3.0-1.10.10.71.21.0
Ambulatory time before self-admin1.11.64.52.1-1.8-1.71.7-1.2-1.20.1-0.7-0.20.3-0.8
Ambulatory time after self-admin1.82.15.0-0.60.90.6-1.11.31.32.2-1.6-1.9-1.6-1.8
Bone: tissue strength0.80.91.71.1-1.3-1.11.1-1.2-1.1-0.7-0.00.50.40.6
Total heroin consumption0.30.41.50.1-0.2-0.5-0.20.40.30.8-0.7-0.7-0.5-1.2
Bone: trabecular number0.30.51.40.7-0.7-1.20.30.00.10.4-1.2-0.8-0.7-0.7
Bone: trabecular spacing0.40.50.9-0.81.00.8-0.80.70.60.90.1-0.7-0.5-0.3
Bone: trabecular thickness0.20.20.50.5-0.5-0.70.3-0.2-0.20.2-0.7-0.4-0.4-0.3
Bone: trabecular tissue density0.71.02.30.2-0.20.80.5-1.1-1.2-0.61.11.31.41.5
Water consumed over 24 hours0.10.20.6-0.20.40.4-0.30.50.6-0.3-0.8-0.3-0.4-0.1
Number of responses in last shaping day0.10.20.4-0.50.40.7-0.40.50.5-0.10.10.1-0.2-0.3