Hub : Genes

LOC108351929

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA XR_010054975.1 0.16 0.07 0.0e+00 0.17 0.17 0.18 0.18 4.9e-19 8.1e-19 4.0e-19 1.3e-19
2 Adipose gene expression LOC108351929 0.24 0.1 0.0e+00 0.12 0.15 0.15 0.14 9.9e-13 4.2e-16 5.2e-16 1.8e-15
3 Adipose mRNA stability LOC108351929 0.09 0.07 9.6e-06 0.03 0.03 0.04 0.04 2.0e-04 6.3e-04 3.1e-05 8.9e-05
4 Adipose isoform ratio XR_010054975.1 0.19 0.09 0.0e+00 0.16 0.17 0.18 0.17 4.6e-17 8.8e-19 2.2e-19 6.0e-19
5 Adipose alternative polyA XR_010054974.1 0.56 0.11 0.0e+00 0.33 0.33 0.34 0.35 1.1e-37 1.1e-37 3.6e-39 2.1e-40
6 Adipose isoform ratio XR_010054974.1 0.58 0.09 0.0e+00 0.34 0.34 0.35 0.36 2.0e-38 8.3e-39 4.5e-40 4.1e-41
7 Adipose intron excision ratio chr9_58066753_58087344 0.58 0.1 0.0e+00 0.36 0.42 0.42 0.41 8.5e-42 4.0e-50 3.5e-51 1.4e-49
8 Adipose alternative polyA XR_005489138.2 0.44 0.13 4.1e-09 0.09 0.06 0.05 0.08 9.9e-10 9.6e-08 1.2e-06 3.9e-09
9 Adipose intron excision ratio chr9_58031350_58035435 0.29 0.11 1.1e-11 0.12 0.11 0.12 0.12 5.9e-13 3.9e-12 5.5e-13 3.5e-13
10 Adipose isoform ratio XR_005489138.2 0.33 0.14 1.7e-09 0.05 0.07 0.07 0.07 2.0e-06 3.8e-08 1.4e-08 1.2e-08
11 Adipose intron excision ratio chr9_58035722_58036242 0.6 0.06 0.0e+00 0.29 0.32 0.34 0.33 2.6e-32 1.3e-36 2.9e-39 4.0e-37

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.23.71.4-1.81.9-0.9-0.4-0.30.01.4-0.6-0.50.8
Area under the delay curve3.25.07.0-1.90.8-2.52.42.62.6-1.82.1-2.4-2.52.2
BMI with tail1.75.915.6-3.63.8-4.03.02.42.3-1.3-0.8-0.2-0.6-0.3
BMI without tail0.10.71.6-1.21.2-0.91.00.90.9-0.90.2-0.3-0.4-0.2
Body weight0.31.22.81.5-1.71.1-1.6-1.3-1.30.4-0.50.30.6-0.4
Weight adjusted by age0.10.20.50.3-0.70.0-0.5-0.4-0.4-0.40.3-0.4-0.30.1
Bone surface0.91.74.21.0-2.01.9-0.20.40.5-0.11.8-1.2-1.21.8
Bone volume0.81.74.31.4-2.11.9-0.7-0.1-0.0-0.41.8-1.1-1.01.5
Breakpoint value in progressive ratio session0.10.20.80.1-0.40.10.00.10.1-0.80.2-0.4-0.20.9
Number of licking bursts0.00.10.70.10.2-0.9-0.0-0.00.0-0.10.4-0.2-0.0-0.0
Context. condit. distance diff. score1.21.54.2-1.82.1-1.01.81.41.2-1.0-0.3-0.3-0.30.3
Locomotion velocity, session 10.60.72.8-1.21.7-0.60.90.50.4-0.2-0.80.50.4-0.8
Locomotion distance, session 10.70.92.5-1.31.6-0.51.00.20.1-0.0-1.40.90.8-1.1
Locomotion velocity, session 21.01.33.5-1.81.9-0.51.60.90.90.3-1.30.70.3-0.7
Locomotion distance, session 21.01.53.6-0.30.40.6-0.0-0.7-0.71.4-1.91.81.7-1.6
Locomotion velocity, session 30.60.73.01.1-0.90.6-0.8-0.6-0.51.7-0.20.80.7-0.1
Locomotion distance, session 30.40.41.20.4-0.40.3-0.6-0.5-0.51.1-0.60.90.8-0.7
Stereotopy head waving bouts, day 30.30.32.10.2-0.2-0.1-0.3-0.3-0.21.5-0.30.80.5-0.4
Stereotopy head waving duration, day 30.50.61.90.6-0.50.5-0.7-0.8-0.71.4-0.51.00.9-0.6
Locomotion velocity, session 71.71.95.2-1.82.3-2.01.61.31.2-1.3-0.2-0.4-0.40.3
Locomotion distance, session 70.71.02.7-1.61.6-1.21.10.80.7-0.6-0.80.40.3-0.3
Stereotopy head waving bouts, day 70.20.20.50.7-0.4-0.1-0.6-0.6-0.60.3-0.10.30.30.1
Stereotopy head waving duration, day 70.50.61.71.3-0.40.4-1.2-1.2-1.20.4-0.20.40.6-0.2
Locomotion velocity, session 80.70.92.8-1.41.7-0.31.30.90.8-0.8-0.7-0.4-0.40.0
Locomotion distance, session 81.21.85.8-2.22.4-0.71.91.11.0-0.7-1.20.40.3-0.4
Degree of sensitization distance0.50.51.6-1.01.1-0.60.80.50.4-1.2-0.0-0.4-0.3-0.0
Degree of sensitization stereotypy0.10.10.70.3-0.3-0.1-0.0-0.1-0.0-0.40.4-0.4-0.30.8
Conditioned locomotion2.12.55.62.1-2.41.0-2.1-1.9-1.91.5-0.50.70.9-1.0
Cocaine response after cond. corrected0.10.10.30.3-0.5-0.2-0.4-0.2-0.2-0.5-0.6-0.00.10.3
Cocaine response after cond. not corrected0.50.71.61.0-0.50.5-1.3-1.0-1.10.0-0.80.60.8-0.4
Cocaine response before conditioning0.60.71.20.80.20.6-1.1-1.0-1.00.70.00.80.9-1.0
Saline control response0.10.10.3-0.20.5-0.60.1-0.0-0.00.20.40.20.2-0.5
Bone: connectivity density0.30.52.00.3-0.91.40.30.30.4-0.00.8-0.6-0.60.8
Bone: cortical apparent density3.04.713.0-3.33.6-3.02.81.71.5-0.0-1.70.80.5-1.3
Bone: cortical area0.10.20.70.2-0.50.1-0.1-0.3-0.30.8-0.40.50.5-0.3
Bone: cortical porosity2.52.79.02.0-3.01.6-1.2-0.2-0.10.22.2-1.5-1.41.9
Bone: cortical porosity3.43.712.02.3-3.51.6-1.5-0.3-0.10.12.7-1.9-1.82.2
Bone: cortical thickness0.40.71.1-1.00.7-0.91.00.40.41.0-1.00.90.7-0.8
Bone: cortical thickness0.20.31.2-0.70.7-1.10.50.30.3-0.0-0.20.20.2-0.3
Bone: cortical tissue density2.84.512.4-3.23.5-3.02.71.71.5-0.1-1.70.80.4-1.3
Condit. Reinf. active minus inactive responses2.52.88.72.9-2.32.2-2.3-1.7-1.60.61.0-0.20.00.5
Condit. Reinf. active-inactive response ratio2.22.46.52.6-1.82.5-2.1-1.6-1.50.70.40.00.2-0.1
Condit. Reinf. active responses1.31.64.42.1-1.91.3-1.4-0.8-0.7-0.31.3-0.8-0.61.3
Condit. Reinf. inactive responses0.60.81.9-0.80.2-1.40.90.90.9-1.00.6-0.7-0.71.2
Incentive salience index mean1.62.03.81.8-2.01.7-1.0-0.3-0.2-0.71.9-1.5-1.31.8
Condit. Reinf. lever presses1.62.35.1-0.0-0.80.60.81.31.4-1.71.9-2.1-2.12.3
Condit. Reinf. active minus inactive responses0.91.44.31.8-2.10.9-1.6-1.2-1.1-0.41.0-0.4-0.10.7
Condit. Reinf. active-inactive response ratio0.91.43.41.5-1.80.8-1.3-0.6-0.5-0.91.7-0.9-0.71.3
Condit. Reinf. active responses0.10.20.50.5-0.7-0.1-0.5-0.6-0.6-0.50.4-0.10.10.2
Condit. Reinf. inactive responses0.60.82.5-1.41.5-1.61.10.60.5-0.6-0.30.10.1-0.4
Condit. Reinf. lever presses1.31.83.4-1.10.4-1.71.21.41.4-1.41.8-1.0-1.11.7
Condit. Reinf. lever reinforcers received0.10.20.60.3-0.7-0.3-0.3-0.3-0.3-0.70.8-0.3-0.10.4
Conditioned reinforcement - actives0.10.30.90.3-0.10.8-0.3-0.3-0.30.9-0.70.70.5-0.1
Conditioned reinforcement - inactives0.20.52.10.9-0.40.9-0.6-0.3-0.31.5-0.50.60.60.1
Conditioned locomotion0.20.30.7-0.50.8-0.70.40.20.20.7-0.90.60.4-0.3
Patch foraging indifference point 0 sec2.98.115.5-3.51.7-1.03.93.63.6-2.71.6-2.6-2.92.4
Patch foraging indifference point AUC0.10.10.4-0.60.5-0.30.60.40.4-0.5-0.2-0.1-0.1-0.2
Delay disc. indifference point, 0s delay3.64.17.1-1.91.4-2.72.22.42.3-1.71.4-1.9-2.11.8
Delay disc. indifference point, 16s delay2.43.54.9-1.30.6-2.01.82.22.2-1.51.9-2.1-2.22.0
Delay disc. indifference point, 2s delay2.52.83.9-1.60.6-2.01.81.91.8-1.81.4-1.8-1.81.7
Delay disc. indifference point, 24s delay0.61.01.8-0.40.1-1.30.71.11.2-0.31.3-1.2-1.31.1
Delay disc. indifference point, 4s delay1.51.62.6-1.51.2-1.51.61.51.5-0.80.8-1.0-1.10.8
Delay disc. indifference point, 8s delay2.44.06.3-1.30.2-1.91.82.12.1-2.12.2-2.5-2.52.3
Indifference point function ln k0.82.63.4-1.70.9-1.51.81.91.8-1.71.2-1.6-1.71.5
Indifference point function log k0.82.63.4-1.70.9-1.51.81.91.8-1.71.2-1.6-1.71.5
Patch foraging total patch changes 0 sec2.67.614.5-3.41.7-1.03.83.53.5-2.71.5-2.6-2.82.4
Patch foraging total patch changes 12 sec0.81.02.5-1.40.6-0.11.61.41.4-0.90.2-0.8-0.80.6
Patch foraging total patch changes 18 sec0.82.05.4-2.32.0-0.72.21.71.6-0.8-0.7-0.3-0.50.1
Patch foraging total patch changes 24 sec0.31.22.7-1.30.2-0.21.61.51.5-0.70.3-1.0-1.21.0
Patch foraging total patch changes 6 sec3.35.611.5-3.01.4-0.73.43.23.1-2.11.1-2.2-2.41.9
Patch foraging time to switch 0 sec1.45.26.72.0-1.01.8-2.4-2.6-2.62.5-2.42.42.4-2.5
Patch foraging water rate 0 sec0.62.23.1-1.70.9-1.01.81.71.7-1.61.3-1.3-1.41.5
Patch foraging water rate 12 sec0.31.43.0-1.71.1-0.61.41.31.2-1.70.3-1.0-1.00.9
Patch foraging water rate 18 sec0.10.21.0-0.30.2-0.10.20.30.2-1.00.3-0.5-0.30.6
Patch foraging water rate 24 sec0.20.30.80.30.00.1-0.7-0.9-0.9-0.1-0.00.50.8-0.5
Patch foraging water rate 6 sec1.32.02.8-1.50.7-1.51.51.61.7-1.41.0-1.3-1.41.4
Seeking ratio, delayed vs. immediate footshock1.31.93.71.9-1.61.7-1.8-1.6-1.61.0-0.70.70.9-0.5
Distance traveled before self-admin0.71.54.22.0-1.90.4-1.4-0.8-0.8-0.61.3-0.9-0.41.5
Distance traveled after self-admin0.91.53.60.3-0.2-0.50.30.70.8-1.81.7-1.8-1.41.9
Extensor digitorum longus weight1.04.012.3-3.23.5-2.52.71.71.6-0.2-0.61.10.8-1.2
Bone: elastic displacement0.10.20.80.2-0.2-0.9-0.2-0.4-0.30.40.40.30.5-0.3
Bone: elastic work0.50.72.11.2-1.50.1-1.0-1.0-0.90.50.80.10.3-0.0
Bone: endosteal estimation1.23.07.72.5-2.82.1-2.0-1.0-1.0-0.71.8-1.4-1.01.6
Bone: endosteal perimeter0.71.84.82.1-2.21.7-1.7-1.0-1.0-0.01.2-0.5-0.11.0
Epididymis fat weight0.10.82.21.3-0.60.8-1.5-1.2-1.2-0.3-0.20.20.5-0.4
Delta time in closed arm before/after self-admin0.50.51.10.0-0.80.60.30.60.70.20.9-0.8-1.01.0
Delta time in open arm before/after self-admin2.63.07.12.3-2.32.7-2.2-2.0-2.00.9-0.60.60.7-0.8
Diff in mean of infusions in LGA sessions0.61.03.50.1-0.5-0.90.30.70.7-1.11.3-1.2-1.11.9
Delay discount exponential model param3.14.15.81.7-0.72.2-2.2-2.4-2.41.7-1.92.22.3-2.0
Extinction: sum of active levers before priming0.10.10.30.5-0.3-0.5-0.3-0.2-0.20.1-0.00.00.20.2
Active lever presses in extinction session 60.50.51.40.1-0.50.20.20.40.3-1.20.9-1.0-0.71.0
Bone: final force1.32.15.42.2-2.32.1-1.8-1.4-1.30.90.60.20.40.3
Bone: final moment1.01.74.01.9-2.02.0-1.5-1.3-1.20.90.40.30.50.1
Food consumed during 24 hour testing period0.10.10.50.20.7-0.6-0.30.00.1-0.20.5-0.2-0.3-0.3
Glucose0.60.92.3-0.20.7-0.6-0.3-0.7-0.71.0-1.21.31.2-1.5
Heart weight0.10.20.5-0.40.4-0.10.60.30.2-0.7-0.6-0.20.20.2
Delay discount hyperbolic model param3.44.46.21.8-0.72.2-2.3-2.5-2.51.7-2.02.32.4-2.1
Intermittent access intake day 1-15 change0.10.51.1-1.10.8-0.90.90.90.9-0.5-0.0-0.3-0.40.5
Intermittent access intake escalation0.10.61.3-1.20.9-1.01.00.90.9-0.3-0.1-0.1-0.40.4
Intermittent access intake escalation 20.50.91.5-0.90.3-0.60.91.21.2-1.00.7-1.0-1.11.2
Intermitt. access day 1 inactive lever presses0.11.02.3-1.11.5-1.20.90.90.91.2-0.70.70.3-0.9
Intermitt. access day 15 inactive lever presses0.21.23.4-1.11.2-1.81.11.31.3-0.70.8-0.7-0.80.4
Intermitt. access escalation Index0.61.95.50.40.51.0-0.8-1.2-1.31.3-1.61.71.8-2.3
Intermittent access day 1 total infusions0.10.20.60.5-0.70.6-0.3-0.3-0.30.8-0.20.30.2-0.1
Intermittent access day 15 total infusions0.10.31.4-0.30.3-0.00.40.20.21.2-0.90.70.4-0.3
Intermittent access terminal intake (last 3 days)0.20.30.8-0.70.3-0.00.80.80.90.7-0.30.0-0.40.4
Intermittent access total infusions0.40.51.80.4-0.50.9-0.3-0.4-0.41.4-0.80.80.6-0.3
Intermittent access day 1 locomotion0.10.10.6-0.50.4-0.80.30.20.20.2-0.40.30.1-0.3
Intermittent access day 15 total locomotion0.20.81.5-1.20.9-1.11.21.11.0-0.50.1-0.3-0.50.7
Intermittent access total locomotion0.81.02.8-1.31.1-1.71.31.21.1-0.30.0-0.3-0.50.5
Intermittent access standard deviation0.10.40.8-0.80.9-0.90.70.70.7-0.0-0.40.1-0.10.3
Left kidney weight0.00.20.40.6-0.3-0.2-0.6-0.4-0.4-0.50.1-0.20.20.0
Right kidney weight0.21.33.7-0.70.6-0.70.91.21.2-1.90.6-1.6-1.31.1
Cocaine induced anxiety0.20.61.0-0.80.5-0.80.90.80.8-1.00.2-0.6-0.70.8
Post-drug Anxiety0.20.30.9-0.60.9-1.00.20.1-0.0-0.4-0.50.30.3-0.2
Baseline Anxiety0.71.11.91.0-0.30.8-1.4-1.4-1.40.9-0.60.91.1-1.3
Tail length3.216.943.75.7-6.06.6-5.2-4.4-4.32.30.31.11.7-0.6
Length with tail4.520.040.06.3-6.26.3-5.9-5.1-5.12.5-0.51.52.3-1.1
Length without tail0.94.79.83.1-2.92.4-3.1-2.6-2.61.1-0.90.71.1-0.5
Times rat made contact with spout0.60.72.31.1-0.9-0.4-1.1-0.7-0.61.50.00.70.6-0.3
Lifetime Intake0.40.51.60.1-0.10.7-0.1-0.3-0.31.3-1.11.00.7-0.6
Liver weight, left2.64.49.52.6-2.43.1-2.5-2.2-2.22.2-1.11.31.5-1.0
Liver weight, right1.83.25.01.9-1.51.1-2.1-2.2-2.21.5-1.61.61.9-1.6
Locomotor activity1.52.45.4-0.70.5-1.51.31.51.5-1.62.3-1.9-1.71.8
Locomotor testing distance1.33.16.2-1.21.1-1.91.41.61.6-2.52.1-2.1-1.81.7
Locomotor testing rearing0.31.12.5-0.91.1-1.30.91.01.0-1.61.1-1.1-0.80.8
Locomotion in novel chamber1.62.27.4-1.82.6-2.70.90.40.2-1.5-1.30.70.8-0.9
Locomotion in novel chamber post-restriction0.10.40.90.1-0.00.7-0.3-0.4-0.41.0-0.90.80.6-0.7
Fecal boli incidents, locomotor time 12.46.311.4-2.00.4-0.92.62.72.7-3.42.5-2.9-2.93.0
Change in fecal boli incidents, locomotor task0.60.61.30.7-0.11.2-0.9-1.0-1.00.0-0.60.60.8-0.8
Time >=10cm from walls, locomotor time 10.10.10.4-0.1-0.6-0.10.20.20.3-0.20.6-0.3-0.30.2
Bouts of movement, locomotor time 11.11.53.6-1.90.7-0.51.91.61.6-1.00.3-0.7-0.80.9
Total resting periods, locomotor time 11.51.74.4-2.11.1-0.82.01.71.7-1.10.3-0.7-0.90.7
Rest time, locomotor task time 10.71.12.2-0.6-0.3-0.21.01.31.4-0.41.2-1.3-1.51.1
Distance moved, locomotor task time 10.20.50.90.7-0.50.9-0.8-0.8-0.90.3-0.30.70.9-0.3
Vertical activity count, locomotor time 10.10.51.10.40.30.0-0.7-0.8-0.80.6-0.81.01.0-0.7
Time >=10cm from walls, locomotor time 20.20.62.01.1-1.40.7-0.9-0.7-0.7-0.50.3-0.5-0.10.3
Bouts of movement, locomotor time 20.51.84.9-2.22.1-1.21.81.51.4-0.7-0.9-0.0-0.2-0.3
Total resting periods, locomotor time 20.52.15.8-2.42.2-1.32.01.61.5-0.7-0.9-0.0-0.3-0.3
Rest time, locomotor task time 20.30.41.7-0.40.40.40.20.10.11.3-0.60.50.3-1.3
Distance moved, locomotor task time 20.10.10.30.3-0.2-0.0-0.3-0.4-0.4-0.6-0.0-0.10.10.3
Vertical activity count, locomotor time 20.10.21.3-0.20.6-1.1-0.0-0.1-0.1-0.2-0.50.00.0-0.2
Light reinforcement 10.31.56.5-1.81.2-2.61.51.11.10.5-0.30.2-0.2-0.5
Light reinforcement 20.30.82.1-0.2-1.0-1.20.40.60.80.31.5-0.8-1.10.9
Bone: marrow area1.22.87.32.4-2.72.0-1.9-1.0-0.9-0.71.7-1.4-1.01.6
Bone: maximum diameter0.10.20.80.7-0.80.9-0.5-0.3-0.30.20.10.00.10.4
Bone: maximum force1.32.77.22.3-2.52.7-1.9-1.7-1.60.90.30.30.50.1
Bone: maximum moment1.12.16.61.9-2.12.6-1.6-1.5-1.50.80.10.40.6-0.1
Mean time between licks in bursts0.21.54.3-1.41.4-2.11.10.40.30.6-1.31.11.1-1.3
Mean num. licks in bursts0.00.10.30.1-0.50.3-0.10.20.20.50.30.0-0.30.4
Cd content in liver0.30.30.91.0-0.80.7-0.8-0.4-0.4-0.20.4-0.4-0.30.6
Co content in liver1.51.83.3-0.7-0.1-0.31.21.61.6-1.01.8-1.7-1.81.6
Cu content in liver0.60.73.21.1-1.11.8-0.9-0.6-0.6-0.30.4-0.5-0.40.3
Fe content in liver0.80.92.71.3-1.61.2-0.7-0.10.00.41.3-0.7-0.71.0
K content in liver1.11.12.3-0.5-0.80.21.11.31.3-0.00.8-1.3-1.51.5
Mg content in liver0.20.20.70.1-0.70.40.20.30.40.1-0.1-0.5-0.60.8
Mn content in liver1.31.46.4-1.41.6-2.51.41.01.0-0.60.1-0.2-0.20.4
Na content in liver2.83.26.7-0.6-0.50.61.31.91.9-1.72.0-2.5-2.62.3
Rb content in liver0.20.20.6-0.50.4-0.40.30.10.10.5-0.70.80.7-0.4
Se content in liver0.10.10.60.10.0-0.10.10.20.2-0.20.7-0.1-0.10.4
Sr content in liver0.20.20.70.0-0.80.40.10.00.10.70.6-0.1-0.3-0.1
Zn content in liver0.20.30.90.3-0.70.9-0.10.10.1-0.10.3-0.6-0.60.7
Bone: minimum diameter0.30.62.21.3-1.50.9-0.9-0.5-0.40.20.5-0.5-0.40.6
Time in familiar zone, hab. session 10.50.52.5-1.00.9-1.60.60.60.5-0.5-0.10.0-0.00.1
Time in novel zone, hab. session 10.91.12.51.6-1.61.3-1.1-0.6-0.5-0.41.0-0.9-0.70.8
Total zone transitions, hab. session 10.40.51.6-0.40.1-1.30.50.60.6-0.80.8-0.8-0.70.7
Total locomotion distance, hab. session 10.10.10.30.4-0.5-0.0-0.4-0.2-0.2-0.40.5-0.2-0.00.4
Locomotion velocity, hab. session 10.10.10.50.4-0.70.2-0.3-0.3-0.20.20.30.10.20.2
Time in familiar zone, hab. session 20.40.42.2-0.30.6-1.50.0-0.0-0.1-1.30.2-0.3-0.10.1
Time in novel zone, hab. session 20.60.72.60.7-0.91.4-0.6-0.5-0.51.6-0.60.60.4-0.4
Total zone transitions, hab. session 20.10.20.6-0.20.10.70.3-0.1-0.20.3-0.70.60.6-0.3
Total locomotion distance, hab. session 20.91.22.61.0-0.91.6-1.0-1.3-1.20.9-0.71.21.3-0.5
Locomotion velocity, hab. session 20.81.02.20.8-0.61.5-0.8-1.1-1.10.8-0.71.31.3-0.6
Novel to familiar place preference ratio2.73.58.62.6-2.91.7-2.5-2.0-1.82.2-0.30.90.8-0.8
Novelty place preference2.83.58.12.5-2.91.4-2.5-2.0-1.92.4-0.51.00.9-1.0
Time in novel zone, NPP test3.44.19.32.7-3.11.5-2.6-2.2-2.12.7-0.61.11.0-1.0
Total zone transitions, NPP test0.30.51.3-0.90.9-0.10.70.20.10.1-1.10.90.9-0.6
Total locomotion distance, NPP test0.20.20.70.0-0.00.8-0.1-0.4-0.4-0.0-0.50.70.8-0.2
Locomotion velocity, NPP test0.10.10.4-0.30.30.50.2-0.0-0.1-0.2-0.30.60.6-0.1
Intraocular pressure1.01.74.7-1.02.0-0.40.1-0.4-0.50.1-2.21.71.5-1.7
Delta distance traveled before/after self-admin0.50.51.8-1.11.3-0.30.70.30.20.0-0.90.50.4-0.9
Delta ambulatory time before/after self-admin0.50.92.3-1.51.5-0.81.41.11.0-0.9-0.1-0.4-0.5-0.1
Parametrial fat weight0.30.61.20.10.70.7-0.4-0.6-0.70.5-1.11.11.1-1.0
Pavlov. Cond. lever latency1.31.64.30.00.4-0.1-0.4-0.7-0.72.1-1.72.01.7-1.5
Pavlov. Cond. magazine entry latency0.60.82.70.6-0.51.3-0.6-0.2-0.2-1.70.9-1.0-0.70.7
Pavlov. Cond. change in total contacts0.30.31.80.2-0.11.4-0.2-0.2-0.3-1.1-0.0-0.4-0.30.3
Pavlov. Cond. index score0.60.73.00.3-0.41.0-0.10.10.0-1.70.9-1.2-0.90.9
Pavlov. Cond. latency score0.81.04.40.2-0.40.70.00.30.2-2.11.1-1.5-1.11.1
Pavlov. Cond. lever contacts0.60.82.9-0.0-0.30.40.30.40.3-1.71.0-1.3-1.10.9
Pavlov. Cond. magazine entry number0.81.05.0-1.20.8-2.21.30.90.90.9-0.20.3-0.0-0.2
Pavlov. Cond. intertrial magazine entries0.91.12.61.5-1.6-0.1-1.2-1.1-1.01.6-0.10.80.8-0.1
Pavlov. Cond. lever-magazine prob. diff.0.50.62.80.2-0.31.0-0.10.0-0.0-1.70.7-1.0-0.80.8
Pavlov. Cond. response bias0.50.63.00.7-0.51.7-0.5-0.3-0.3-1.10.5-0.7-0.50.5
Pavlov. Cond. lever latency0.81.12.00.9-0.51.2-1.0-1.1-1.21.2-1.40.80.8-1.2
Pavlov. Cond. magazine entry latency0.10.10.60.10.2-0.80.10.10.20.40.60.20.2-0.2
Pavlov. Cond. change in total contacts0.41.02.5-0.0-0.6-0.10.40.80.8-1.11.6-1.2-1.11.5
Pavlov. Cond. index score0.30.51.6-0.40.2-1.00.60.70.7-0.61.2-0.4-0.30.7
Pavlov. Cond. latency score0.20.31.2-0.20.1-0.80.30.50.5-0.41.1-0.2-0.20.5
Pavlov. Cond. lever contacts0.81.22.0-0.80.5-1.31.01.21.2-1.41.4-0.9-0.91.2
Pavlov. Cond. magazine entry number0.10.10.5-0.40.50.30.10.0-0.0-0.5-0.7-0.0-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.20.51.7-0.60.8-0.7-0.0-0.3-0.40.3-1.30.80.7-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.41.0-0.50.2-1.00.60.60.7-0.41.0-0.2-0.20.6
Pavlov. Cond. response bias0.30.41.3-0.2-0.0-0.90.30.60.6-0.51.1-0.5-0.40.8
Time in closed arm before self-admin0.40.61.51.1-1.20.7-0.7-0.4-0.3-0.61.1-0.9-0.60.7
Time in closed arm after self-admin2.83.27.0-0.0-1.00.00.81.51.6-1.72.7-2.5-2.52.5
Time in open arm before self-admin1.41.73.3-1.11.8-1.50.5-0.2-0.21.1-1.51.81.6-1.5
Time in open arm after self-admin2.22.54.31.7-1.11.5-1.9-2.1-2.11.0-1.21.41.6-1.3
Bone: periosteal estimation0.81.96.12.0-2.51.6-1.5-0.8-0.8-0.01.4-0.8-0.51.2
Bone: periosteal perimeter0.51.03.41.6-1.81.1-1.3-1.0-1.00.50.30.10.30.4
Bone: post-yield work0.40.72.11.3-1.11.4-1.1-0.7-0.70.00.4-0.2-0.00.3
Progressive ratio test 1 active lever presses0.20.30.7-0.60.50.10.60.30.30.8-0.70.50.2-0.7
Progressive ratio test 1 breakpoint0.10.20.5-0.40.30.20.50.30.20.7-0.60.40.2-0.6
Progressive ratio test 1 inactive lever presses0.61.63.3-1.21.8-0.40.90.30.31.4-1.81.51.2-1.5
Progressive ratio test 2 active lever presses0.20.31.50.2-0.41.0-0.1-0.0-0.01.2-0.60.60.4-0.1
Progressive ratio test 2 breakpoint0.20.31.60.2-0.31.0-0.00.00.01.3-0.60.60.3-0.1
Progressive ratio test 2 inactive lever presses0.20.62.20.5-0.11.1-0.4-0.4-0.41.5-0.81.00.8-0.5
Incentive Sensitization - Responses0.20.62.01.0-1.01.4-0.9-0.6-0.60.8-0.20.40.40.1
Incentive Sensitization - Breakpoint0.30.61.91.0-0.91.4-0.9-0.7-0.60.9-0.20.40.40.1
Sum of active levers in priming session hrs 5-60.60.61.71.1-0.60.3-1.3-1.0-1.1-0.2-0.40.30.8-0.2
Progressive ratio0.20.51.20.6-0.40.6-0.8-0.9-0.81.0-0.30.70.5-1.1
Food seeking constrained by brief footshock1.01.35.51.3-1.32.3-1.2-1.1-1.00.8-0.50.20.1-0.5
Seeking ratio, punishment vs. effort0.00.10.3-0.1-0.00.20.30.30.2-0.5-0.3-0.3-0.20.5
Retroperitoneal fat weight0.20.91.60.40.60.6-0.6-0.9-0.90.9-1.31.21.2-1.3
Reaction time number correct1.03.47.60.10.60.8-0.7-1.4-1.52.5-2.42.72.6-2.2
Reaction time mean minus median0.10.92.71.7-1.60.8-1.2-1.0-1.0-0.10.6-0.30.10.4
Reaction time mean minus median AUC0.10.82.41.6-1.50.8-1.1-1.0-1.0-0.00.5-0.30.10.4
Reaction time num false alarms1.11.94.2-1.92.0-1.91.91.71.6-0.1-0.30.0-0.4-0.2
Reaction time num false alarms AUC0.71.73.6-1.81.9-1.91.81.61.60.2-0.30.1-0.3-0.2
Reaction time trials correct on left1.03.47.60.10.60.8-0.7-1.4-1.52.5-2.42.72.6-2.2
Reaction time trials on left1.13.78.20.30.50.9-0.9-1.6-1.62.6-2.52.92.7-2.3
Reaction time mean2.24.812.43.5-2.52.6-3.2-2.7-2.70.5-0.20.61.2-0.3
Reaction time mean AUC1.84.411.53.4-2.32.3-3.1-2.6-2.60.5-0.30.71.3-0.4
Median of all reaction times3.25.113.03.6-2.52.7-3.4-2.8-2.80.5-0.30.71.3-0.4
Reaction time omissions1.01.63.01.7-1.31.0-1.7-1.6-1.51.1-0.20.91.2-0.7
Reaction time false alarm rate2.12.95.2-1.71.4-2.02.12.22.3-1.11.1-1.4-1.71.1
Reaction time premature initiation rate3.35.17.4-1.50.7-2.31.92.32.3-2.72.4-2.7-2.62.5
Reaction time premature initiations0.41.12.1-1.31.0-1.51.31.21.1-1.00.7-0.8-0.80.9
Std. dev. reaction times0.72.47.22.7-2.21.4-2.3-1.9-1.90.10.30.00.60.2
Reaction time trials completed1.13.78.20.30.50.9-0.9-1.6-1.62.6-2.52.92.7-2.3
Reaction time trials AUC1.03.68.00.20.51.0-0.8-1.5-1.62.5-2.42.82.7-2.3
Run reversals in cocaine runway, females1.11.31.91.3-0.71.1-1.4-1.4-1.41.1-0.71.01.1-1.0
Run reversals in cocaine runway, males1.01.12.0-0.60.6-0.91.11.31.3-1.10.9-1.1-1.01.4
Latency to leave start box in cocaine runway1.72.36.4-2.32.5-1.72.11.61.5-0.4-0.8-0.1-0.4-0.6
Latency to leave start box in cocaine runway, F1.41.83.8-1.71.9-1.81.81.61.6-0.50.1-0.6-0.80.2
Latency to leave start box in cocaine runway, M1.81.74.9-2.22.2-1.01.50.70.6-0.3-1.70.60.4-1.5
Std. dev. time between licks in bursts0.81.54.0-1.81.0-1.82.01.61.60.4-0.2-0.1-0.4-0.1
Total sessions with >9 infusions0.60.72.2-1.11.2-0.10.70.20.10.6-1.51.00.7-1.0
Short access day 1 total inactive lever presses0.30.61.50.20.5-0.8-0.4-0.6-0.61.0-0.91.00.9-1.2
Short access day 10 total inactive lever presses0.00.10.4-0.20.5-0.40.20.50.50.60.20.20.0-0.0
Short access day 1 total infusions0.40.72.5-0.50.9-0.50.1-0.3-0.40.5-1.61.21.1-1.0
Short access day 10 total infusions0.10.20.7-0.2-0.10.80.30.20.10.8-0.70.50.2-0.2
Short access total infusions0.20.30.9-0.50.40.10.30.10.00.5-1.00.70.5-0.6
Short access day 1 locomotion0.71.13.9-0.20.40.3-0.2-0.6-0.71.2-2.01.51.3-1.4
Short access day 10 total locomotion0.83.16.2-2.01.6-2.52.02.22.2-1.40.9-1.2-1.51.1
Short access total locomotion0.81.23.0-1.11.7-1.20.60.20.10.7-1.71.30.9-1.2
One hour access (0.3 mA shock)0.30.41.00.0-0.80.70.30.60.60.20.5-0.5-0.71.0
Compulsive drug intake0.30.41.5-0.81.0-1.20.60.40.4-0.60.2-0.1-0.0-0.1
One hour access (shock baseline)0.30.73.20.9-1.21.8-0.6-0.4-0.41.0-0.20.20.10.2
Social response proportion0.50.61.61.1-1.30.8-1.0-0.8-0.8-0.50.6-0.3-0.00.3
Social responses0.50.61.6-0.1-0.3-1.00.30.30.3-1.21.1-1.2-0.80.6
Social time0.71.12.21.3-0.90.6-1.4-1.4-1.50.1-0.30.71.1-0.8
Soleus weight0.71.95.5-0.91.1-0.3-0.0-0.9-1.00.3-2.31.81.8-2.3
Bone: stiffness0.91.77.31.7-1.92.7-1.4-1.1-1.10.6-0.1-0.00.10.2
Tibialis anterior weight0.41.54.1-2.01.8-1.71.71.21.2-0.1-0.10.60.3-0.6
Time to tail flick, vehicle, before self-admin1.11.43.5-0.6-0.30.21.01.41.5-0.81.2-1.3-1.51.9
Time to tail flick, vehicle, after self-admin0.51.01.8-0.3-0.6-1.10.71.11.20.21.3-1.0-1.21.3
Time to tail flick, test, before self-admin0.20.20.7-0.30.7-0.80.40.30.30.7-0.20.2-0.0-0.2
Time to tail flick, test, after self-admin0.30.31.0-0.50.9-0.50.30.00.00.3-1.00.60.5-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.70.10.1-0.3-0.2-0.3-0.30.9-0.30.50.4-0.9
Delta time to tail flick, test, before/after SA0.10.10.9-0.20.20.60.1-0.1-0.1-0.9-0.20.00.20.0
Tibia length1.95.412.23.5-3.11.9-3.3-3.1-3.11.1-0.10.71.2-1.0
Ambulatory time before self-admin0.41.34.52.1-1.70.3-1.7-1.2-1.2-0.00.7-0.20.30.8
Ambulatory time after self-admin1.32.14.9-0.60.6-0.81.11.31.3-2.21.6-1.9-1.61.8
Bone: tissue strength0.91.02.91.1-1.11.7-1.1-1.2-1.10.70.00.50.4-0.6
Total heroin consumption0.30.41.50.1-0.5-0.20.20.40.3-0.80.7-0.7-0.51.2
Bone: trabecular number0.40.83.00.7-1.21.7-0.30.00.1-0.41.2-0.8-0.70.7
Bone: trabecular spacing0.40.62.3-0.80.8-1.50.80.70.6-0.9-0.1-0.7-0.50.3
Bone: trabecular thickness0.10.20.50.5-0.70.6-0.3-0.2-0.2-0.20.7-0.4-0.40.3
Bone: trabecular tissue density0.61.02.30.20.80.5-0.5-1.1-1.20.6-1.11.31.4-1.5
Water consumed over 24 hours0.10.31.0-0.20.4-1.00.30.50.60.40.8-0.3-0.40.1
Number of responses in last shaping day0.10.20.4-0.50.7-0.50.40.50.50.2-0.10.1-0.20.3