Hub : Genes

LOC108351520

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression LOC108351520 0.17 0.1 1.6e-03 0.08 0.1 0.1 0.1 3.7e-03 1.6e-03 1.4e-03 1.5e-03
2 pVTA intron excision ratio chr7_113777983_113783830 0.17 0.09 1.5e-06 0.06 0.14 0.14 0.1 1.8e-03 1.2e-06 1.1e-06 3.2e-05
3 PL intron excision ratio chr7_113783228_113783830 0.1 0.05 1.5e-12 0.12 0.11 0.12 0.12 3.2e-13 2.5e-12 7.5e-13 1.2e-12
4 BLA intron excision ratio chr7_113777983_113783830 0.14 0.08 1.7e-06 0.1 0.1 0.08 0.09 5.2e-06 7.4e-06 5.7e-05 2.7e-05
5 BLA intron excision ratio chr7_113783228_113783830 0.14 0.08 1.6e-06 0.1 0.1 0.08 0.09 5.0e-06 7.1e-06 5.6e-05 2.5e-05
6 BLA gene expression LOC108351520 0.14 0.07 2.5e-06 0.09 0.09 0.08 0.08 1.2e-05 2.5e-05 3.0e-05 6.0e-05
7 Brain gene expression LOC108351520 0.42 0.12 0.0e+00 0.32 0.3 0.32 0.32 6.2e-31 5.0e-28 1.0e-30 1.7e-30
8 PL gene expression LOC108351520 0.14 0.06 1.2e-13 0.14 0.13 0.13 0.13 1.3e-15 8.9e-14 2.2e-14 2.3e-14
9 Brain mRNA stability LOC108351520 0.05 0.03 8.5e-05 0.05 0.04 0.05 0.04 8.7e-06 9.0e-05 1.0e-05 5.3e-05
10 NAcc gene expression LOC108351520 0.2 0.09 0.0e+00 0.15 0.17 0.15 0.16 3.9e-17 7.7e-19 1.8e-17 1.5e-17
11 Brain intron excision ratio chr7_113783228_113783830 0.25 0.09 0.0e+00 0.23 0.25 0.24 0.26 2.1e-21 2.8e-23 2.0e-22 7.3e-24
12 pVTA gene expression LOC108351520 0.3 0.13 3.8e-09 0.22 0.18 0.22 0.21 1.0e-09 3.3e-08 6.1e-10 2.4e-09
13 LHb intron excision ratio chr7_113783228_113783830 0.24 0.11 2.6e-04 0.07 0.16 0.12 0.14 8.9e-03 1.5e-04 1.0e-03 3.0e-04
14 OFC gene expression LOC108351520 0.22 0.12 6.6e-03 0.04 0.06 0.06 0.04 3.7e-02 1.2e-02 1.6e-02 4.3e-02
15 NAcc intron excision ratio chr7_113783228_113783830 0.18 0.09 5.6e-17 0.13 0.16 0.16 0.17 3.4e-15 1.2e-17 1.6e-18 4.3e-19
16 LHb intron excision ratio chr7_113777983_113783830 0.25 0.12 2.2e-04 0.07 0.15 0.12 0.14 9.3e-03 2.1e-04 1.1e-03 3.0e-04
17 NAcc intron excision ratio chr7_113777983_113783830 0.11 0.06 1.8e-07 0.07 0.07 0.07 0.08 4.7e-09 2.8e-08 5.1e-09 2.4e-09
18 pVTA intron excision ratio chr7_113783228_113783830 0.32 0.15 3.3e-12 0.24 0.25 0.26 0.24 1.0e-10 4.9e-11 7.5e-12 1.2e-10
19 PL intron excision ratio chr7_113777983_113783830 0.1 0.05 5.5e-11 0.08 0.1 0.09 0.1 4.2e-09 1.3e-11 6.2e-10 6.8e-11
20 Brain intron excision ratio chr7_113777983_113783830 0.2 0.09 2.5e-12 0.09 0.14 0.13 0.14 6.3e-09 6.5e-13 2.6e-12 4.3e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.30.41.0-0.7-0.3-0.90.9-0.9-1.0-0.5-0.60.70.60.6-1.00.60.60.6-0.5-0.5-0.4-0.2-0.3
Area under the delay curve0.30.31.2-1.1-1.1-0.30.3-0.3-0.7-0.7-0.80.60.50.00.00.20.40.2-0.20.0-0.2-0.00.3
BMI with tail1.34.17.81.7-0.22.5-2.62.60.90.30.8-2.1-0.6-2.5-0.3-2.50.2-2.82.42.82.72.22.2
BMI without tail0.00.10.40.60.00.0-0.20.20.5-0.20.10.1-0.2-0.20.3-0.3-0.3-0.30.20.50.5-0.00.1
Body weight1.04.07.92.61.62.6-2.82.82.01.91.9-2.4-1.8-2.40.6-2.2-0.9-2.02.01.51.31.81.5
Weight adjusted by age0.80.91.80.81.1-0.10.1-0.11.31.11.2-0.2-1.20.61.30.7-1.20.8-0.8-1.2-1.3-0.9-1.0
Bone surface0.40.72.20.41.5-0.60.6-0.60.20.50.70.3-0.70.9-0.61.0-0.31.0-1.0-1.2-1.3-0.7-1.2
Bone volume0.10.20.80.30.9-0.40.3-0.30.10.30.40.0-0.50.4-0.30.6-0.20.5-0.6-0.6-0.6-0.3-0.7
Breakpoint value in progressive ratio session0.20.30.9-0.1-0.60.00.2-0.2-0.7-0.9-0.70.20.8-0.0-0.6-0.40.8-0.30.40.50.70.50.4
Number of licking bursts0.30.30.6-0.4-0.8-0.80.8-0.8-0.4-0.5-0.40.70.40.7-0.10.50.00.6-0.5-0.5-0.4-0.6-0.5
Context. condit. distance diff. score4.75.710.42.82.13.1-3.13.12.82.62.6-3.2-2.7-2.32.8-1.9-1.9-2.01.81.11.21.21.0
Locomotion velocity, session 11.01.03.71.11.9-0.20.1-0.11.01.41.4-0.1-1.30.60.40.8-1.00.9-0.9-1.2-1.4-0.7-1.4
Locomotion distance, session 11.72.13.9-1.00.0-2.01.9-1.9-0.4-0.2-0.21.70.41.9-0.22.0-0.31.8-1.9-1.7-1.8-1.8-1.7
Locomotion velocity, session 20.30.41.41.01.20.2-0.20.20.80.51.2-0.6-1.0-0.1-0.30.1-0.5-0.4-0.20.3-0.30.1-0.4
Locomotion distance, session 21.92.66.1-2.0-1.7-2.12.1-2.1-1.8-1.9-1.81.92.01.3-2.51.11.80.9-0.9-0.3-0.3-0.4-0.2
Locomotion velocity, session 30.80.92.91.01.40.3-0.40.41.41.21.4-0.3-1.50.21.70.6-1.20.4-0.7-0.6-0.7-0.6-1.0
Locomotion distance, session 31.21.32.7-0.90.3-1.21.2-1.2-0.10.10.01.2-0.21.30.61.5-1.01.4-1.5-1.4-1.5-1.7-1.6
Stereotopy head waving bouts, day 30.50.61.61.21.20.8-0.80.80.91.11.1-1.1-1.1-0.70.0-0.4-0.2-0.40.40.10.10.70.2
Stereotopy head waving duration, day 32.52.97.52.72.41.9-1.91.92.22.22.4-2.2-2.3-1.31.3-1.0-1.1-1.00.90.30.31.00.3
Locomotion velocity, session 70.20.20.60.10.30.5-0.50.50.50.30.60.0-0.8-0.30.60.3-0.7-0.2-0.30.2-0.2-0.2-0.0
Locomotion distance, session 70.60.72.3-1.4-1.50.1-0.10.1-1.2-1.2-1.20.70.9-0.4-0.9-0.00.9-0.40.10.90.50.51.0
Stereotopy head waving bouts, day 73.74.212.22.93.51.4-1.41.43.13.33.1-2.0-3.1-0.62.3-0.1-2.30.2-0.1-1.1-1.0-0.1-1.2
Stereotopy head waving duration, day 72.73.39.22.53.01.2-1.11.12.82.92.7-1.6-2.8-0.52.2-0.0-2.30.2-0.2-1.0-0.9-0.3-1.2
Locomotion velocity, session 81.82.15.82.41.31.7-1.61.61.71.41.6-2.4-1.2-1.20.9-1.5-0.6-1.41.40.81.11.10.5
Locomotion distance, session 80.71.02.51.21.01.1-1.11.11.61.21.3-1.5-1.3-0.81.2-0.6-0.9-0.80.50.30.50.30.3
Degree of sensitization distance2.92.96.90.6-0.91.9-1.81.8-0.1-0.6-0.3-1.50.4-2.1-0.9-2.11.3-2.32.12.52.22.32.6
Degree of sensitization stereotypy3.03.39.22.33.01.0-1.01.02.83.02.6-1.5-2.7-0.42.30.1-2.40.4-0.2-1.3-1.1-0.5-1.3
Conditioned locomotion0.70.82.40.81.00.7-0.70.71.31.41.2-0.9-1.3-0.51.6-0.1-1.4-0.2-0.0-0.3-0.1-0.3-0.1
Cocaine response after cond. corrected0.10.10.30.30.30.3-0.30.30.40.30.5-0.1-0.5-0.00.40.2-0.5-0.0-0.20.00.1-0.3-0.2
Cocaine response after cond. not corrected0.10.20.50.40.40.2-0.10.10.70.20.7-0.1-0.60.20.60.3-0.70.0-0.4-0.10.1-0.5-0.2
Cocaine response before conditioning0.10.10.3-0.2-0.0-0.40.6-0.60.0-0.40.20.20.10.30.20.30.00.2-0.3-0.1-0.2-0.30.0
Saline control response0.91.24.01.12.0-0.20.3-0.31.51.01.5-0.5-1.40.61.10.7-1.40.8-0.8-1.3-1.1-1.0-1.1
Bone: connectivity density0.20.31.0-0.5-0.1-0.60.6-0.6-1.0-0.3-0.50.40.40.4-1.00.30.50.5-0.3-0.5-0.30.0-0.2
Bone: cortical apparent density0.50.61.4-1.1-0.6-1.00.9-0.9-1.2-0.6-0.91.20.80.7-0.80.70.60.7-0.6-0.5-0.5-0.3-0.3
Bone: cortical area1.11.73.31.81.21.7-1.81.81.41.21.4-1.2-1.3-1.51.0-1.3-0.5-1.11.20.90.81.10.8
Bone: cortical porosity0.30.41.60.80.50.7-0.70.70.80.51.0-0.5-0.8-0.41.2-0.3-0.5-0.30.30.10.40.20.1
Bone: cortical porosity0.80.91.91.40.91.1-1.11.11.10.91.3-0.9-1.2-0.81.4-0.7-0.6-0.50.60.20.60.50.3
Bone: cortical thickness0.81.22.7-0.0-1.20.7-0.80.8-0.7-0.8-0.8-0.11.0-1.2-0.4-1.51.2-1.21.61.61.51.51.6
Bone: cortical thickness1.11.32.9-0.1-1.10.7-0.80.8-0.6-0.8-0.8-0.50.9-1.3-1.0-1.60.9-1.41.71.71.51.31.6
Bone: cortical tissue density0.40.61.4-1.1-0.7-0.90.8-0.8-1.2-0.6-0.91.10.80.6-0.80.60.70.7-0.6-0.5-0.5-0.3-0.3
Condit. Reinf. active minus inactive responses0.30.31.4-0.8-0.9-0.20.2-0.2-0.9-0.9-0.70.50.70.1-0.60.11.2-0.3-0.00.60.10.50.4
Condit. Reinf. active-inactive response ratio0.20.20.50.50.40.7-0.70.70.40.40.5-0.5-0.5-0.40.4-0.20.1-0.40.20.30.10.50.0
Condit. Reinf. active responses1.11.43.5-1.8-1.5-1.31.3-1.3-1.5-1.9-1.31.31.40.8-1.40.71.40.3-0.60.2-0.2-0.10.1
Condit. Reinf. inactive responses2.12.55.2-2.3-1.6-2.12.1-2.1-1.7-2.1-1.71.81.71.3-1.81.21.11.0-1.1-0.4-0.6-0.9-0.2
Incentive salience index mean0.70.92.4-1.4-1.4-0.60.6-0.6-1.4-1.5-1.20.81.20.2-1.20.21.5-0.3-0.10.80.10.50.6
Condit. Reinf. lever presses0.71.02.6-1.5-1.2-1.11.1-1.1-1.2-1.6-1.01.11.10.5-1.40.71.2-0.0-0.60.5-0.4-0.00.3
Condit. Reinf. active minus inactive responses0.40.51.80.0-1.00.3-0.20.2-0.8-0.4-0.7-0.20.8-0.6-0.4-0.71.3-0.50.70.60.91.11.0
Condit. Reinf. active-inactive response ratio0.80.82.90.1-1.10.4-0.30.3-1.1-0.5-0.8-0.20.9-0.8-0.7-0.91.7-0.61.00.81.01.51.2
Condit. Reinf. active responses0.40.61.21.10.31.1-0.90.90.50.60.5-1.0-0.3-0.90.3-0.80.4-0.80.80.60.61.00.7
Condit. Reinf. inactive responses0.80.92.21.31.21.3-1.21.21.51.01.2-1.2-1.2-0.80.8-0.5-0.8-0.80.40.60.00.40.2
Condit. Reinf. lever presses0.20.31.5-0.3-0.8-0.50.5-0.5-0.7-0.8-0.90.10.90.5-0.50.21.20.2-0.1-0.20.20.4-0.0
Condit. Reinf. lever reinforcers received0.20.31.10.7-0.10.8-0.60.60.10.30.1-0.8-0.0-0.7-0.0-0.60.7-0.60.60.40.61.00.7
Conditioned reinforcement - actives0.40.40.70.6-0.40.9-0.80.80.70.80.8-0.6-0.8-0.70.8-0.3-0.6-0.40.30.20.20.20.2
Conditioned reinforcement - inactives0.40.41.3-0.4-1.00.1-0.20.2-0.9-0.8-0.80.10.9-0.4-0.2-0.61.1-0.60.60.80.20.80.8
Conditioned locomotion1.51.83.71.20.01.8-1.91.90.70.70.8-1.6-0.8-1.90.5-1.5-0.0-1.71.51.61.31.51.4
Patch foraging indifference point 0 sec0.40.62.4-0.6-0.4-0.60.7-0.7-1.1-1.0-0.90.61.10.7-1.50.11.20.5-0.0-0.40.10.2-0.2
Patch foraging indifference point AUC0.10.10.8-0.3-0.3-0.40.4-0.4-0.2-0.2-0.20.50.10.4-0.90.30.30.3-0.3-0.2-0.0-0.1-0.3
Delay disc. indifference point, 0s delay0.70.71.50.7-0.01.1-1.01.00.50.00.4-1.1-0.4-1.01.0-1.00.0-1.20.91.20.80.91.1
Delay disc. indifference point, 16s delay1.21.32.7-1.6-0.7-1.41.3-1.3-1.3-1.1-1.41.41.11.1-1.11.00.71.2-0.9-1.0-0.8-0.7-0.6
Delay disc. indifference point, 2s delay0.30.31.1-0.5-1.10.5-0.50.5-0.1-0.4-0.1-0.10.0-0.60.5-0.40.2-0.70.40.80.50.40.8
Delay disc. indifference point, 24s delay0.40.30.9-0.30.1-0.20.3-0.30.10.80.40.7-0.50.30.40.7-0.60.8-0.7-0.8-1.0-0.7-0.8
Delay disc. indifference point, 4s delay0.60.61.8-0.4-1.30.1-0.10.1-0.9-0.9-0.9-0.10.8-0.4-0.3-0.71.3-0.70.70.90.71.00.9
Delay disc. indifference point, 8s delay0.70.72.5-1.6-1.3-0.80.8-0.8-1.1-1.0-1.21.20.90.4-0.20.60.40.7-0.6-0.4-0.4-0.4-0.0
Indifference point function ln k0.60.92.51.11.11.2-1.11.10.91.01.1-1.6-0.9-0.90.8-0.8-0.5-0.90.80.50.50.70.4
Indifference point function log k0.60.92.51.11.11.2-1.11.10.91.01.1-1.6-0.9-0.90.8-0.8-0.5-0.90.80.50.50.70.4
Patch foraging total patch changes 0 sec0.40.72.8-0.8-0.5-0.80.9-0.9-1.2-1.1-1.10.71.20.8-1.70.21.20.6-0.1-0.5-0.00.1-0.3
Patch foraging total patch changes 12 sec0.20.21.80.1-0.4-0.10.1-0.1-0.7-0.4-0.20.00.40.0-1.3-0.21.0-0.10.20.20.40.70.2
Patch foraging total patch changes 18 sec0.30.41.7-0.4-0.4-0.30.3-0.3-0.8-0.7-0.90.00.9-0.0-1.3-0.31.3-0.20.40.30.40.70.4
Patch foraging total patch changes 24 sec0.20.21.3-0.30.3-0.60.5-0.5-0.5-0.4-0.50.70.40.5-1.10.40.40.5-0.4-0.3-0.4-0.2-0.3
Patch foraging total patch changes 6 sec0.30.42.3-0.0-0.9-0.50.6-0.6-0.6-1.1-0.60.20.80.5-1.5-0.11.1-0.00.20.20.60.3-0.1
Patch foraging time to switch 0 sec0.10.10.5-0.30.3-0.10.0-0.0-0.10.30.10.3-0.20.20.60.7-0.10.4-0.7-0.4-0.7-0.3-0.1
Patch foraging water rate 0 sec0.30.42.30.3-0.5-0.50.6-0.6-0.4-1.1-0.5-0.10.90.4-1.5-0.60.7-0.20.60.31.10.2-0.1
Patch foraging water rate 12 sec0.30.41.4-0.10.9-0.80.9-0.9-0.1-0.2-0.20.70.20.8-1.20.50.00.7-0.5-0.6-0.4-0.6-0.8
Patch foraging water rate 18 sec0.81.12.9-0.30.0-1.41.7-1.7-0.8-0.8-0.41.10.71.6-0.61.10.51.2-1.1-1.1-0.6-0.9-1.2
Patch foraging water rate 24 sec0.20.21.01.00.2-0.10.0-0.0-0.1-0.3-0.1-0.30.3-0.2-0.9-0.50.7-0.30.60.40.70.70.2
Patch foraging water rate 6 sec0.91.33.0-0.30.7-1.41.4-1.40.4-0.10.21.0-0.21.5-0.41.5-0.41.6-1.5-1.6-1.5-1.3-1.7
Seeking ratio, delayed vs. immediate footshock2.93.37.6-2.6-1.8-2.02.0-2.0-2.4-2.2-2.32.32.11.6-2.81.31.61.3-1.2-0.8-0.2-0.7-0.7
Distance traveled before self-admin1.61.76.0-1.1-2.40.2-0.20.2-1.5-1.7-1.60.11.5-0.8-1.6-0.91.6-1.11.01.51.61.21.5
Distance traveled after self-admin0.50.53.40.0-0.60.3-0.20.2-0.3-0.5-0.4-0.20.6-0.5-1.9-0.81.1-0.60.90.80.91.00.7
Extensor digitorum longus weight0.10.51.2-0.2-0.0-1.01.0-1.00.0-0.4-0.30.90.41.10.80.5-0.20.8-0.6-0.7-0.6-0.9-0.9
Bone: elastic displacement0.80.93.81.32.0-0.10.1-0.11.11.11.2-0.3-1.20.40.80.4-1.20.5-0.5-0.8-1.2-0.7-1.0
Bone: elastic work1.51.95.52.31.71.6-1.61.61.51.31.6-1.9-1.4-1.31.2-1.3-0.6-1.21.20.90.51.10.6
Bone: endosteal estimation1.73.712.92.83.60.9-0.90.93.12.63.1-1.6-3.1-0.01.50.5-2.20.2-0.7-1.1-1.1-0.6-1.3
Bone: endosteal perimeter2.65.414.13.03.81.9-1.91.93.63.43.6-1.9-3.7-0.82.60.2-2.8-0.1-0.4-0.8-1.0-0.4-1.0
Epididymis fat weight2.35.410.32.62.43.1-3.23.22.82.92.7-2.8-2.9-2.51.3-1.4-2.1-2.01.31.30.61.01.1
Delta time in closed arm before/after self-admin1.41.43.00.5-0.81.5-1.31.30.40.10.3-1.5-0.3-1.50.0-1.30.2-1.71.31.61.51.31.5
Delta time in open arm before/after self-admin0.60.61.10.11.1-0.50.6-0.60.40.70.30.3-0.40.7-0.10.9-0.81.0-0.9-1.0-1.0-1.0-1.0
Diff in mean of infusions in LGA sessions0.60.64.1-0.9-2.0-0.50.5-0.5-1.1-1.0-1.10.30.90.4-1.40.20.70.1-0.20.10.5-0.00.1
Delay discount exponential model param0.30.31.31.11.10.4-0.40.40.70.60.7-0.7-0.5-0.1-0.1-0.3-0.4-0.30.30.10.30.1-0.1
Extinction: sum of active levers before priming0.10.11.0-0.0-1.00.2-0.10.1-0.5-0.7-0.3-0.10.3-0.10.0-0.30.4-0.30.30.40.60.30.3
Active lever presses in extinction session 60.30.30.90.5-1.00.4-0.20.20.1-0.5-0.1-0.40.2-0.3-0.0-0.60.3-0.70.60.70.90.50.6
Bone: final force1.22.04.31.2-0.21.7-1.81.80.10.10.3-1.5-0.1-1.8-0.1-1.90.9-1.61.91.51.82.11.7
Bone: final moment1.32.14.41.50.11.8-1.81.80.20.30.4-1.5-0.3-1.8-0.2-2.00.8-1.62.01.51.82.11.6
Food consumed during 24 hour testing period1.21.42.41.2-0.41.5-1.41.40.50.30.6-1.2-0.3-1.61.0-1.60.3-1.41.51.41.21.51.5
Glucose0.30.40.9-1.0-0.9-0.70.7-0.7-0.7-1.0-0.80.70.80.6-0.80.50.80.2-0.40.1-0.1-0.1-0.0
Heart weight2.23.17.11.70.12.1-2.02.00.60.40.6-2.4-0.2-2.3-0.1-2.70.4-2.22.62.02.12.12.1
Delay discount hyperbolic model param0.20.21.20.91.10.1-0.20.20.60.60.6-0.5-0.40.1-0.2-0.1-0.4-0.00.0-0.20.1-0.1-0.4
Intermittent access intake day 1-15 change0.30.30.8-0.5-0.1-0.90.5-0.5-0.6-0.7-0.80.70.70.5-0.50.30.40.5-0.3-0.3-0.6-0.2-0.3
Intermittent access intake escalation0.30.30.9-0.6-0.0-1.00.6-0.6-0.6-0.8-0.90.70.70.6-0.20.30.50.6-0.3-0.4-0.7-0.2-0.3
Intermittent access intake escalation 20.20.20.9-0.10.5-0.60.4-0.4-0.2-0.2-0.30.50.20.50.30.3-0.00.6-0.3-0.6-0.9-0.4-0.4
Intermitt. access day 1 inactive lever presses1.01.12.40.5-0.30.6-0.70.7-0.6-0.7-0.7-1.10.7-1.0-0.6-1.31.3-1.51.41.51.21.51.3
Intermitt. access day 15 inactive lever presses2.62.86.80.3-2.00.9-1.11.1-1.1-1.1-1.2-1.21.2-1.6-1.1-2.01.9-2.12.12.32.62.22.2
Intermitt. access escalation Index0.20.20.5-0.3-0.6-0.20.0-0.0-0.6-0.6-0.60.00.6-0.2-0.5-0.40.7-0.10.40.10.50.50.3
Intermittent access day 1 total infusions0.81.02.00.7-0.21.3-1.31.30.20.50.5-0.9-0.4-1.4-0.2-1.20.2-1.31.21.31.01.31.1
Intermittent access day 15 total infusions0.20.20.6-0.1-0.30.0-0.20.2-0.7-0.5-0.60.20.6-0.4-0.6-0.60.8-0.30.60.40.10.70.6
Intermittent access terminal intake (last 3 days)0.00.00.10.10.30.3-0.40.4-0.10.20.0-0.0-0.1-0.30.1-0.3-0.0-0.10.30.1-0.20.30.3
Intermittent access total infusions0.30.30.70.2-0.20.7-0.70.7-0.20.1-0.0-0.30.0-0.9-0.0-0.80.3-0.60.80.60.40.80.8
Intermittent access day 1 locomotion0.50.61.20.2-0.90.8-0.80.8-0.1-0.1-0.0-0.8-0.0-1.00.1-0.90.4-1.10.91.11.10.90.9
Intermittent access day 15 total locomotion0.10.10.30.1-0.10.4-0.40.4-0.10.30.1-0.4-0.1-0.50.3-0.40.1-0.30.40.30.30.50.3
Intermittent access total locomotion0.60.71.30.0-0.90.9-0.90.9-0.3-0.1-0.1-0.70.1-1.1-0.4-0.90.6-1.01.01.11.11.11.0
Intermittent access standard deviation0.70.81.70.50.30.9-1.01.0-0.3-0.1-0.3-0.60.3-1.3-0.3-1.30.7-1.11.31.10.81.31.3
Left kidney weight8.523.945.06.73.66.6-6.56.54.44.54.8-6.3-4.2-5.52.6-5.1-1.5-4.94.83.73.74.53.4
Right kidney weight9.426.449.56.63.37.0-6.96.94.34.24.8-6.7-4.1-5.92.2-5.6-1.3-5.55.34.34.24.93.9
Cocaine induced anxiety1.31.54.90.7-1.50.9-1.01.0-0.6-0.5-0.7-0.60.7-1.2-1.2-1.51.1-1.21.61.42.21.61.5
Post-drug Anxiety0.40.51.90.7-0.90.3-0.50.5-0.3-0.1-0.5-0.30.4-0.5-1.1-0.90.7-0.50.90.51.40.90.6
Baseline Anxiety1.21.32.7-0.80.4-1.31.3-1.30.0-0.10.01.1-0.11.40.61.5-0.71.4-1.5-1.5-1.6-1.5-1.5
Tail length0.30.82.00.00.7-1.00.9-0.90.30.2-0.00.9-0.11.00.80.9-0.71.2-0.9-1.2-1.4-1.2-1.1
Length with tail0.31.14.21.62.00.8-0.90.91.51.81.3-1.0-1.4-0.51.0-0.3-0.90.10.2-0.6-0.90.2-0.3
Length without tail0.71.53.11.41.11.8-1.71.70.91.41.2-1.7-1.1-1.4-0.2-1.10.1-1.01.10.50.61.50.8
Times rat made contact with spout0.70.81.70.7-0.60.9-0.90.90.4-0.20.1-1.00.0-1.10.1-1.30.2-1.21.31.31.01.01.2
Lifetime Intake1.11.32.70.3-0.71.3-1.21.2-0.4-0.2-0.3-0.80.3-1.5-0.2-1.50.9-1.31.61.41.41.61.6
Liver weight, left1.11.86.01.32.51.1-1.01.02.02.22.0-1.0-2.2-0.50.70.3-1.70.1-0.4-0.6-1.2-0.3-0.5
Liver weight, right2.13.58.82.12.71.9-2.02.02.72.72.6-1.7-3.0-1.22.3-0.2-2.4-0.50.1-0.2-0.8-0.0-0.3
Locomotor activity1.42.25.92.41.51.7-1.61.62.21.91.9-1.7-1.8-1.21.4-1.0-1.1-0.90.90.40.60.80.3
Locomotor testing distance0.00.00.20.0-0.1-0.10.2-0.20.30.10.00.4-0.10.10.20.3-0.00.4-0.3-0.4-0.1-0.1-0.0
Locomotor testing rearing1.01.52.61.50.91.5-1.51.51.61.31.4-1.4-1.5-1.51.4-0.9-1.0-1.00.80.70.40.60.9
Locomotion in novel chamber2.12.56.00.52.4-0.80.7-0.71.71.31.30.4-1.41.01.91.6-2.21.6-1.7-2.0-2.4-2.1-1.7
Locomotion in novel chamber post-restriction0.70.81.9-1.4-0.1-1.01.1-1.1-0.6-0.6-0.61.20.40.9-0.21.2-0.21.0-1.2-0.9-1.0-1.1-0.8
Fecal boli incidents, locomotor time 10.30.31.0-0.4-1.0-0.70.8-0.8-0.5-0.9-0.70.50.60.60.00.50.40.3-0.4-0.10.1-0.4-0.2
Change in fecal boli incidents, locomotor task1.00.94.20.91.70.5-0.80.81.22.11.3-0.3-1.3-0.40.4-0.0-1.20.5-0.1-0.8-0.9-0.2-0.6
Time >=10cm from walls, locomotor time 10.00.00.2-0.00.20.4-0.30.3-0.10.10.30.0-0.2-0.2-0.4-0.00.2-0.10.00.10.30.30.1
Bouts of movement, locomotor time 10.20.20.7-0.4-0.80.5-0.60.6-0.2-0.0-0.10.0-0.1-0.60.1-0.30.0-0.40.30.50.60.40.6
Total resting periods, locomotor time 10.40.41.8-0.9-1.40.3-0.40.4-0.8-0.6-0.70.30.5-0.6-0.4-0.40.6-0.40.40.60.90.50.9
Rest time, locomotor task time 11.31.43.3-0.7-1.60.8-0.80.8-0.9-1.1-1.2-0.30.9-1.2-0.8-1.11.1-1.31.11.61.81.31.8
Distance moved, locomotor task time 10.80.92.91.21.60.6-0.50.51.21.31.5-1.0-1.3-0.31.7-0.0-0.9-0.3-0.1-0.0-0.9-0.0-0.3
Vertical activity count, locomotor time 10.10.20.80.50.8-0.20.3-0.30.10.40.3-0.2-0.30.30.50.1-0.00.3-0.1-0.4-0.9-0.0-0.5
Time >=10cm from walls, locomotor time 20.20.20.4-0.40.6-0.20.3-0.3-0.1-0.00.10.6-0.10.5-0.40.6-0.20.5-0.6-0.5-0.6-0.4-0.4
Bouts of movement, locomotor time 20.90.92.2-0.4-1.50.5-0.60.6-0.6-0.6-0.6-0.50.6-1.2-0.8-1.00.9-1.11.11.31.31.21.5
Total resting periods, locomotor time 21.01.03.0-0.5-1.70.4-0.50.5-0.7-0.8-0.8-0.40.8-1.1-1.1-1.01.1-1.11.11.21.51.21.5
Rest time, locomotor task time 20.20.32.0-0.7-1.4-0.20.2-0.2-0.6-0.7-0.70.40.70.1-0.5-0.00.6-0.10.10.20.60.10.3
Distance moved, locomotor task time 20.81.03.11.21.51.0-1.01.01.11.01.2-1.0-1.2-0.81.8-0.4-1.0-0.80.30.7-0.50.20.3
Vertical activity count, locomotor time 20.40.52.81.11.70.5-0.50.50.80.80.8-0.6-0.8-0.30.8-0.3-0.6-0.40.30.2-0.60.1-0.0
Light reinforcement 10.51.03.71.01.90.4-0.40.41.41.41.5-0.1-1.50.30.90.7-1.10.6-0.8-1.0-0.4-0.5-1.0
Light reinforcement 20.40.51.30.70.81.0-1.11.11.11.01.0-0.4-1.1-0.70.4-0.2-0.5-0.40.10.20.60.50.4
Bone: marrow area1.83.913.72.93.71.0-1.01.03.22.73.2-1.7-3.2-0.11.50.5-2.20.2-0.6-1.1-1.1-0.5-1.3
Bone: maximum diameter3.05.512.33.52.92.9-2.92.93.12.83.0-2.6-2.8-2.31.7-1.8-1.4-1.61.71.00.81.50.9
Bone: maximum force2.03.56.12.10.42.4-2.52.51.10.71.1-2.2-0.8-2.30.7-2.30.4-2.22.32.02.22.31.8
Bone: maximum moment2.23.86.42.40.72.5-2.52.51.30.91.2-2.3-1.0-2.40.6-2.40.3-2.32.42.12.22.41.8
Mean time between licks in bursts0.30.51.2-1.1-0.9-0.80.7-0.7-0.6-0.6-0.91.00.80.70.50.50.10.7-0.4-0.5-0.5-0.7-0.3
Mean num. licks in bursts1.21.42.61.10.81.6-1.61.61.10.80.9-1.6-0.8-1.60.7-1.4-0.3-1.41.31.20.71.11.2
Cd content in liver1.11.25.01.51.01.1-0.90.91.60.91.1-1.4-0.9-0.72.2-1.0-1.5-0.70.80.30.2-0.10.2
Co content in liver0.50.62.30.7-0.40.7-0.80.80.4-0.10.3-0.70.1-0.70.6-1.2-0.0-0.81.10.71.50.60.9
Cu content in liver2.63.25.8-2.2-1.0-2.42.3-2.3-1.6-1.5-1.82.21.52.0-1.22.01.12.0-1.9-1.6-1.8-1.3-1.0
Fe content in liver0.30.42.20.91.5-0.10.1-0.10.70.61.0-0.3-0.80.40.00.4-0.40.3-0.4-0.5-0.8-0.2-0.8
K content in liver0.50.52.1-0.5-0.8-0.80.7-0.7-0.9-1.1-0.90.41.00.4-0.90.31.50.0-0.20.20.10.30.4
Mg content in liver1.11.14.5-1.1-1.4-0.80.8-0.8-1.7-1.5-1.50.81.60.5-1.20.42.10.2-0.20.10.00.60.6
Mn content in liver0.30.41.60.60.50.6-0.50.50.90.61.0-0.8-0.9-0.21.30.2-0.8-0.2-0.3-0.1-0.1-0.2-0.0
Na content in liver1.71.83.3-1.8-1.3-1.81.7-1.7-1.4-1.3-1.31.51.41.6-0.91.40.81.2-1.3-1.0-0.7-1.0-0.7
Rb content in liver0.10.10.50.1-0.10.0-0.00.0-0.4-0.1-0.2-0.00.4-0.10.0-0.20.7-0.10.20.1-0.00.50.4
Se content in liver0.50.71.8-0.50.2-0.90.9-0.9-0.3-0.20.00.9-0.01.1-0.21.3-0.20.9-1.3-0.9-1.0-1.0-1.0
Sr content in liver0.60.51.2-1.1-1.0-0.90.9-0.9-0.6-0.8-0.71.10.90.70.30.4-0.20.4-0.4-0.0-0.3-1.0-0.4
Zn content in liver1.01.12.2-0.70.1-1.51.4-1.4-0.3-0.2-0.31.00.31.40.61.3-0.21.4-1.2-1.5-1.3-1.2-1.2
Bone: minimum diameter0.81.53.81.81.91.2-1.21.21.91.71.9-0.8-1.9-0.61.6-0.0-1.3-0.1-0.1-0.2-0.3-0.0-0.3
Time in familiar zone, hab. session 10.10.10.40.30.60.4-0.50.50.20.40.4-0.0-0.5-0.20.40.2-0.6-0.1-0.20.1-0.6-0.2-0.2
Time in novel zone, hab. session 10.60.51.51.20.70.4-0.40.41.20.71.0-1.2-0.7-0.31.1-0.7-0.8-0.40.6-0.00.70.0-0.1
Total zone transitions, hab. session 12.43.36.3-1.6-0.1-2.52.5-2.5-0.8-0.6-0.72.10.62.3-0.92.3-0.22.3-2.3-2.1-2.1-2.1-1.9
Total locomotion distance, hab. session 12.23.16.4-0.31.4-1.81.8-1.80.60.60.81.2-0.92.10.22.5-1.42.1-2.5-2.2-2.4-2.4-2.5
Locomotion velocity, hab. session 11.92.75.9-0.70.8-2.02.0-2.00.10.10.31.5-0.42.1-0.32.4-0.82.0-2.4-2.0-2.2-2.1-2.2
Time in familiar zone, hab. session 20.80.83.00.21.20.3-0.30.30.50.91.00.3-1.20.31.10.8-1.70.7-0.9-0.8-1.4-1.2-0.9
Time in novel zone, hab. session 20.50.51.70.5-0.5-0.10.1-0.10.1-0.4-0.5-0.70.7-0.3-0.6-0.91.1-0.71.00.61.31.00.6
Total zone transitions, hab. session 20.50.62.4-0.5-0.1-1.31.3-1.3-0.3-0.6-0.60.60.70.9-1.50.70.80.6-0.7-0.5-0.6-0.3-0.4
Total locomotion distance, hab. session 20.40.51.4-0.6-0.4-1.21.2-1.2-0.3-0.7-0.50.60.60.9-1.10.80.50.4-0.7-0.3-0.4-0.5-0.5
Locomotion velocity, hab. session 20.81.02.5-1.0-0.5-1.61.6-1.6-0.5-1.0-0.71.00.81.2-1.31.20.60.7-1.1-0.5-0.7-0.8-0.7
Novel to familiar place preference ratio2.22.35.52.32.31.4-1.41.42.32.31.9-2.1-1.9-0.81.3-1.1-1.6-0.41.0-0.40.20.2-0.1
Novelty place preference3.03.17.52.52.61.7-1.71.72.72.62.2-2.3-2.2-1.11.6-1.3-1.9-0.51.1-0.30.20.3-0.1
Time in novel zone, NPP test3.73.88.72.82.82.0-1.91.93.02.82.4-2.6-2.4-1.31.8-1.5-2.0-0.71.3-0.20.40.40.0
Total zone transitions, NPP test1.72.45.7-1.10.0-2.42.3-2.3-0.5-0.5-0.61.60.72.0-0.21.9-0.11.8-1.9-1.7-1.9-1.8-1.7
Total locomotion distance, NPP test0.81.12.9-0.8-0.2-1.71.7-1.7-0.6-0.6-0.51.00.61.4-0.51.20.21.0-1.2-0.9-1.0-1.0-1.1
Locomotion velocity, NPP test1.41.94.4-1.4-0.5-2.12.1-2.1-0.8-0.8-0.71.60.71.7-0.41.80.11.4-1.7-1.2-1.4-1.5-1.3
Intraocular pressure0.30.41.30.50.70.9-0.80.80.41.00.8-0.5-0.8-0.71.1-0.3-0.8-0.40.30.3-0.10.10.2
Delta distance traveled before/after self-admin1.21.35.31.72.30.5-0.40.41.91.91.8-0.8-1.6-0.00.4-0.0-1.20.2-0.1-0.6-0.9-0.3-0.8
Delta ambulatory time before/after self-admin1.21.44.42.02.10.5-0.50.52.01.91.9-0.9-1.6-0.00.5-0.2-1.10.20.1-0.6-0.8-0.2-0.8
Parametrial fat weight0.20.41.4-0.3-0.70.6-0.60.6-0.1-0.4-0.1-0.50.3-0.6-0.4-0.80.4-0.80.80.81.20.70.8
Pavlov. Cond. lever latency1.11.34.61.51.21.3-1.31.31.51.71.1-1.4-1.1-0.82.1-0.9-1.2-0.30.8-0.20.40.2-0.1
Pavlov. Cond. magazine entry latency1.31.75.3-1.9-2.0-0.80.9-0.9-1.8-2.2-1.61.31.70.3-2.30.21.5-0.1-0.10.80.50.20.9
Pavlov. Cond. change in total contacts2.02.18.0-1.7-2.1-1.01.0-1.0-2.0-2.3-1.81.21.90.3-2.80.11.9-0.30.11.00.60.40.9
Pavlov. Cond. index score1.41.76.5-1.5-2.0-0.50.6-0.6-1.8-2.1-1.40.91.6-0.1-2.6-0.21.7-0.60.31.30.80.71.2
Pavlov. Cond. latency score1.21.55.8-1.3-1.8-0.60.6-0.6-1.6-2.0-1.30.91.5-0.1-2.4-0.21.6-0.50.31.10.70.61.1
Pavlov. Cond. lever contacts1.61.96.8-1.9-1.9-1.31.3-1.3-1.8-2.2-1.51.41.60.6-2.60.71.50.1-0.50.60.1-0.10.5
Pavlov. Cond. magazine entry number1.11.44.11.71.80.6-0.60.61.72.01.5-1.1-1.5-0.12.00.0-1.30.3-0.1-1.0-0.4-0.2-0.9
Pavlov. Cond. intertrial magazine entries0.70.81.6-0.9-0.6-1.31.3-1.3-1.1-0.7-1.11.11.11.0-1.20.50.91.0-0.4-0.8-0.4-0.3-0.4
Pavlov. Cond. lever-magazine prob. diff.1.41.75.9-1.8-2.0-0.70.7-0.7-1.8-2.1-1.51.21.60.0-2.40.01.6-0.40.11.10.60.51.1
Pavlov. Cond. response bias1.72.06.5-2.0-2.2-0.90.9-0.9-2.1-2.3-1.71.31.70.2-2.50.21.7-0.3-0.11.00.50.41.0
Pavlov. Cond. lever latency0.70.92.10.50.61.3-1.31.31.11.11.0-0.5-1.1-1.21.3-0.7-1.4-0.60.60.70.40.00.6
Pavlov. Cond. magazine entry latency3.74.29.7-2.1-2.6-2.22.2-2.2-2.9-2.5-2.91.92.91.5-3.10.83.01.2-0.5-0.70.20.2-0.1
Pavlov. Cond. change in total contacts1.52.19.4-0.6-1.5-0.80.8-0.8-2.1-1.6-1.80.11.90.4-3.1-0.33.0-0.00.50.10.91.50.7
Pavlov. Cond. index score2.32.97.1-1.6-1.9-1.91.9-1.9-2.4-2.1-2.31.32.41.4-2.60.72.70.9-0.5-0.70.10.3-0.2
Pavlov. Cond. latency score2.83.58.5-1.8-2.2-2.02.0-2.0-2.7-2.4-2.61.52.71.5-2.90.72.90.9-0.5-0.60.20.4-0.1
Pavlov. Cond. lever contacts0.71.03.3-0.6-0.9-1.21.2-1.2-1.3-1.2-1.20.51.31.1-1.50.61.80.5-0.5-0.6-0.10.3-0.4
Pavlov. Cond. magazine entry number2.32.88.01.62.11.6-1.61.62.51.92.4-1.3-2.3-1.02.8-0.5-2.7-0.80.30.5-0.3-0.6-0.1
Pavlov. Cond. intertrial magazine entries2.63.47.01.2-0.32.3-2.22.21.00.30.7-2.0-0.4-2.31.4-2.4-0.3-2.62.32.62.21.62.2
Pavlov. Cond. lever-magazine prob. diff.2.32.97.1-1.6-1.8-1.91.9-1.9-2.4-2.0-2.21.42.31.5-2.70.82.61.1-0.6-0.8-0.10.2-0.3
Pavlov. Cond. response bias1.11.55.1-0.8-1.3-1.21.3-1.3-1.9-1.4-1.70.61.71.0-2.10.52.30.6-0.3-0.50.10.6-0.1
Time in closed arm before self-admin4.14.78.3-2.4-1.4-2.82.8-2.8-2.0-2.3-2.12.92.12.6-2.51.91.22.3-1.7-1.9-1.1-1.5-1.5
Time in closed arm after self-admin0.30.41.50.2-0.50.6-0.50.50.5-0.10.4-0.6-0.3-0.6-1.2-0.5-0.1-0.90.50.70.60.40.8
Time in open arm before self-admin0.40.42.40.01.00.2-0.20.20.70.80.7-0.1-0.9-0.01.60.5-1.00.1-0.6-0.2-0.8-0.6-0.4
Time in open arm after self-admin1.01.13.3-0.21.8-0.50.6-0.60.40.80.50.4-0.70.81.31.3-1.11.2-1.3-1.2-1.7-1.3-1.3
Bone: periosteal estimation1.73.49.82.93.11.6-1.61.63.02.52.9-1.8-2.8-0.91.7-0.4-1.8-0.50.3-0.2-0.30.3-0.4
Bone: periosteal perimeter3.35.411.53.23.12.6-2.72.73.43.23.3-2.3-3.4-1.72.6-0.9-2.3-1.00.70.30.10.60.1
Bone: post-yield work0.50.61.60.5-0.40.7-0.70.70.2-0.5-0.1-1.10.3-0.80.2-1.00.6-1.31.01.21.11.01.0
Progressive ratio test 1 active lever presses0.90.92.3-0.0-0.50.7-0.80.8-0.6-0.5-0.5-0.70.5-1.3-0.1-1.20.9-1.31.31.50.81.31.4
Progressive ratio test 1 breakpoint0.50.51.5-0.2-0.40.6-0.60.6-0.5-0.4-0.4-0.50.4-1.0-0.1-0.90.6-1.10.91.20.51.01.1
Progressive ratio test 1 inactive lever presses2.12.35.5-0.2-1.10.9-0.90.9-1.4-1.6-1.5-0.81.4-1.6-0.4-1.71.9-2.01.82.31.52.02.2
Progressive ratio test 2 active lever presses0.70.82.3-0.5-1.50.2-0.20.2-1.3-1.0-1.10.21.1-0.6-0.6-0.81.3-0.60.91.00.91.01.0
Progressive ratio test 2 breakpoint1.01.13.1-0.3-1.80.5-0.30.3-1.2-1.1-1.10.01.2-0.8-0.6-1.11.5-1.01.11.41.31.31.3
Progressive ratio test 2 inactive lever presses1.61.94.7-0.8-2.2-0.30.2-0.2-2.1-1.9-2.00.42.0-0.4-1.2-0.92.1-0.91.11.31.21.31.3
Incentive Sensitization - Responses0.60.61.7-0.4-1.3-0.00.3-0.3-1.3-1.3-1.20.51.3-0.0-0.3-0.41.3-0.30.50.60.50.70.6
Incentive Sensitization - Breakpoint0.70.71.9-0.3-1.40.20.1-0.1-1.2-1.2-1.20.31.2-0.3-0.2-0.71.4-0.50.80.80.80.90.8
Sum of active levers in priming session hrs 5-60.10.10.3-0.1-0.2-0.20.3-0.3-0.4-0.6-0.2-0.40.30.1-0.30.10.2-0.1-0.10.20.2-0.0-0.0
Progressive ratio0.20.21.2-0.1-1.1-0.30.5-0.5-0.6-0.8-0.60.30.70.3-0.1-0.10.8-0.00.20.10.40.20.1
Food seeking constrained by brief footshock1.21.42.71.3-0.01.6-1.61.60.91.21.0-1.1-1.0-1.61.4-1.2-0.3-1.31.21.11.01.21.0
Seeking ratio, punishment vs. effort0.50.71.60.60.61.1-1.21.20.60.90.6-0.8-0.8-1.20.5-0.7-0.4-0.90.70.80.50.70.8
Retroperitoneal fat weight2.47.815.62.91.73.9-3.93.92.72.62.7-3.5-2.7-3.41.7-2.5-1.3-3.02.32.42.02.32.1
Reaction time number correct1.31.83.8-0.90.5-1.31.4-1.40.20.20.01.6-0.41.60.01.9-1.01.8-2.0-1.7-1.9-1.8-1.8
Reaction time mean minus median0.20.31.30.70.20.3-0.10.10.80.60.9-0.5-0.6-0.10.9-0.4-1.10.20.3-0.50.0-0.5-0.3
Reaction time mean minus median AUC0.40.51.30.70.10.9-0.70.70.80.80.8-0.9-0.7-0.81.0-0.9-1.1-0.40.80.10.30.00.4
Reaction time num false alarms0.70.92.20.80.90.10.0-0.00.70.81.40.2-1.20.71.40.9-1.51.0-1.0-1.4-0.7-1.1-1.2
Reaction time num false alarms AUC0.71.02.10.70.8-0.10.1-0.10.70.91.40.3-1.20.91.21.0-1.51.1-1.1-1.5-0.7-1.2-1.3
Reaction time trials correct on left1.31.83.8-0.90.5-1.31.4-1.40.20.20.01.6-0.41.60.01.9-1.01.8-2.0-1.7-1.9-1.8-1.8
Reaction time trials on left1.42.04.1-0.90.5-1.31.5-1.50.20.20.01.6-0.41.60.02.0-1.01.9-2.0-1.8-1.9-1.9-1.9
Reaction time mean0.10.10.3-0.3-0.5-0.40.5-0.5-0.4-0.2-0.30.40.40.2-0.20.10.00.5-0.1-0.50.0-0.3-0.2
Reaction time mean AUC0.10.10.2-0.4-0.5-0.40.5-0.5-0.5-0.2-0.30.40.40.2-0.30.10.00.4-0.1-0.4-0.1-0.2-0.1
Median of all reaction times0.20.30.8-0.7-0.7-0.70.7-0.7-0.9-0.5-0.70.70.80.4-0.70.20.50.6-0.2-0.4-0.0-0.2-0.2
Reaction time omissions0.20.31.0-0.3-0.2-0.60.7-0.70.10.10.00.3-0.00.7-0.20.5-0.80.8-0.6-0.9-0.6-1.0-0.6
Reaction time false alarm rate0.20.31.40.90.10.6-0.60.60.40.41.0-0.4-0.6-0.11.2-0.2-0.7-0.00.2-0.20.5-0.1-0.1
Reaction time premature initiation rate0.40.52.6-0.0-0.8-0.40.4-0.4-0.9-1.1-0.80.70.80.4-1.30.11.60.2-0.0-0.00.60.70.0
Reaction time premature initiations0.40.62.0-0.5-0.5-0.80.9-0.9-0.7-0.8-0.81.20.60.9-1.40.81.10.8-0.7-0.6-0.1-0.0-0.6
Std. dev. reaction times0.30.40.90.90.40.7-0.50.50.90.90.9-0.7-0.8-0.61.0-0.6-0.9-0.00.5-0.30.2-0.00.0
Reaction time trials completed1.42.04.1-0.90.5-1.31.5-1.50.20.20.01.6-0.41.60.02.0-1.01.9-2.0-1.8-1.9-1.9-1.9
Reaction time trials AUC1.11.63.5-0.80.5-1.21.3-1.30.30.30.11.4-0.51.50.11.9-0.91.7-1.9-1.7-1.8-1.7-1.8
Run reversals in cocaine runway, females1.41.33.1-0.70.9-0.90.9-0.90.50.70.70.8-0.91.2-0.21.7-1.11.3-1.8-1.4-1.6-1.6-1.6
Run reversals in cocaine runway, males0.90.83.11.31.40.7-0.70.71.21.81.5-0.6-1.4-0.40.6-0.1-1.20.00.1-0.2-0.5-0.2-0.5
Latency to leave start box in cocaine runway0.10.10.30.30.40.4-0.50.50.20.00.2-0.4-0.1-0.5-0.2-0.4-0.1-0.40.40.40.40.30.5
Latency to leave start box in cocaine runway, F0.30.30.9-0.60.2-0.60.6-0.6-0.2-0.5-0.20.70.20.6-0.90.6-0.00.6-0.6-0.5-0.3-0.6-0.4
Latency to leave start box in cocaine runway, M1.91.83.51.1-0.11.7-1.71.70.30.40.3-1.7-0.2-1.90.6-1.70.3-1.81.71.61.41.51.8
Std. dev. time between licks in bursts0.81.01.9-1.0-1.1-1.31.2-1.2-1.4-1.1-1.31.11.31.0-0.50.61.40.6-0.5-0.3-0.5-0.1-0.4
Total sessions with >9 infusions1.71.83.50.9-0.21.8-1.71.70.20.10.2-1.4-0.2-1.90.3-1.80.5-1.71.81.61.61.81.7
Short access day 1 total inactive lever presses1.31.42.71.30.11.3-1.41.40.30.50.5-1.6-0.3-1.4-0.8-1.60.5-1.41.61.31.61.61.2
Short access day 10 total inactive lever presses0.50.51.71.30.70.7-0.80.80.81.00.7-0.9-0.7-0.70.1-0.7-0.4-0.80.70.60.50.50.3
Short access day 1 total infusions2.02.13.81.1-0.11.9-1.71.70.20.20.2-1.6-0.2-2.00.0-1.90.7-1.81.91.71.82.01.9
Short access day 10 total infusions0.91.02.10.1-1.11.1-1.11.1-0.3-0.3-0.3-0.70.3-1.3-0.0-1.20.6-1.41.21.41.41.31.4
Short access total infusions3.03.46.80.8-1.12.1-2.02.0-0.3-0.3-0.3-1.70.3-2.5-0.1-2.41.1-2.42.42.52.62.52.6
Short access day 1 locomotion0.80.82.6-0.4-1.30.7-0.70.7-0.5-0.8-0.6-0.50.4-0.9-0.9-0.80.8-1.10.91.21.61.01.2
Short access day 10 total locomotion0.50.52.9-0.8-1.70.5-0.30.3-0.5-0.9-0.5-0.10.4-0.6-0.4-0.30.5-0.80.31.01.30.50.8
Short access total locomotion2.12.15.70.1-1.71.6-1.61.6-0.3-0.5-0.3-1.20.2-1.9-0.2-1.60.7-2.01.62.22.41.71.9
One hour access (0.3 mA shock)0.20.31.2-0.7-0.9-0.30.4-0.4-0.9-0.5-0.81.10.70.20.10.20.30.4-0.2-0.2-0.2-0.10.1
Compulsive drug intake1.41.42.6-0.6-0.5-1.61.6-1.6-0.9-0.7-0.91.61.01.6-0.21.10.31.6-1.1-1.5-0.9-1.1-1.2
One hour access (shock baseline)0.10.10.5-0.7-0.20.5-0.60.6-0.2-0.0-0.10.1-0.1-0.6-0.1-0.20.0-0.40.20.5-0.00.30.6
Social response proportion0.40.40.90.2-0.10.2-0.10.1-0.4-0.7-0.6-0.70.8-0.5-0.5-0.90.8-0.60.90.51.00.81.0
Social responses0.20.20.50.60.7-0.20.4-0.40.60.20.40.3-0.40.50.50.5-0.40.6-0.6-0.7-0.4-0.5-0.5
Social time1.31.73.9-1.8-1.9-1.51.6-1.6-1.6-2.0-1.61.51.61.1-1.01.01.00.8-0.9-0.3-0.1-0.7-0.2
Soleus weight0.10.30.7-0.2-0.6-0.50.5-0.5-0.6-0.9-0.7-0.20.90.4-0.6-0.10.8-0.20.10.30.30.20.1
Bone: stiffness1.32.03.61.3-0.11.8-1.91.90.70.40.6-1.4-0.5-1.80.8-1.80.4-1.71.81.71.81.81.6
Tibialis anterior weight0.51.84.8-1.7-2.2-1.41.4-1.4-1.8-1.8-2.11.82.10.9-0.70.21.20.7-0.1-0.10.5-0.40.3
Time to tail flick, vehicle, before self-admin0.30.41.20.90.6-0.10.2-0.20.70.41.0-0.6-0.70.51.10.3-0.70.2-0.4-0.5-0.4-0.5-0.7
Time to tail flick, vehicle, after self-admin2.32.54.80.21.3-1.21.3-1.30.91.00.91.4-1.01.71.11.9-1.72.0-2.0-2.1-2.2-2.2-2.2
Time to tail flick, test, before self-admin0.60.61.90.40.70.2-0.00.01.30.91.10.1-1.10.21.10.6-1.40.2-0.7-0.3-1.0-0.9-0.6
Time to tail flick, test, after self-admin0.91.01.8-1.3-0.2-1.21.2-1.2-0.6-0.4-0.61.00.41.2-0.11.3-0.11.1-1.2-1.2-1.3-1.1-1.0
Delta time to tail flick, vehicle, before/after SA0.10.10.8-0.3-0.5-0.40.3-0.3-0.5-0.2-0.60.90.40.2-0.20.20.30.4-0.1-0.2-0.1-0.1-0.1
Delta time to tail flick, test, before/after SA1.81.62.9-1.6-0.3-1.71.6-1.6-1.4-1.0-1.31.11.11.6-1.11.20.71.4-1.1-1.4-1.0-0.9-1.1
Tibia length0.51.53.21.81.51.6-1.71.71.01.61.2-1.6-1.2-1.40.9-1.2-0.3-0.71.10.20.21.20.7
Ambulatory time before self-admin0.90.91.7-0.8-1.20.2-0.10.1-1.3-1.3-1.20.21.2-0.7-0.7-0.71.3-0.90.81.31.01.01.2
Ambulatory time after self-admin0.30.43.0-0.2-1.0-0.50.6-0.6-0.2-0.3-0.30.60.50.5-1.70.10.60.5-0.1-0.30.10.0-0.4
Bone: tissue strength0.10.10.70.80.60.4-0.40.40.40.50.3-0.3-0.4-0.20.4-0.20.1-0.10.2-0.0-0.10.4-0.0
Total heroin consumption0.30.32.00.3-1.40.20.0-0.0-0.4-0.8-0.3-0.50.5-0.20.3-0.50.6-0.40.60.51.00.60.5
Bone: trabecular number0.10.20.5-0.10.6-0.20.1-0.1-0.10.60.40.3-0.70.10.20.6-0.70.6-0.6-0.7-0.6-0.5-0.5
Bone: trabecular spacing0.91.22.50.8-0.11.4-1.31.30.50.30.2-1.3-0.2-1.50.5-1.40.3-1.61.41.60.91.31.3
Bone: trabecular thickness0.10.20.4-0.3-0.3-0.60.6-0.6-0.2-0.3-0.30.40.20.4-0.40.50.20.4-0.5-0.40.2-0.3-0.3
Bone: trabecular tissue density1.11.63.7-1.0-1.4-1.61.6-1.6-1.4-1.8-1.51.31.81.3-1.90.51.40.8-0.4-0.50.5-0.4-0.3
Water consumed over 24 hours0.50.61.81.40.30.9-0.80.80.90.80.9-1.0-0.5-0.70.6-1.1-0.3-0.61.00.40.50.60.4
Number of responses in last shaping day1.81.86.1-1.4-2.3-0.70.7-0.7-2.0-2.5-2.10.62.00.1-1.3-0.32.0-0.40.40.81.00.70.9