Hub : Genes

LOC108351432

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_29600910_29601491 0.09 0.06 2.0e-03 0.01 0.02 0.02 0 5.0e-02 3.0e-03 3.9e-03 7.6e-02
2 Brain gene expression LOC108351432 0.2 0.07 0.0e+00 0.2 0.19 0.2 0.2 3.5e-18 8.8e-18 1.0e-18 1.1e-18
3 BLA gene expression LOC108351432 0.33 0.1 2.3e-15 0.25 0.28 0.29 0.29 7.8e-14 4.3e-15 7.0e-16 5.5e-16
4 OFC gene expression LOC108351432 0.34 0.11 1.3e-06 0.19 0.23 0.22 0.25 2.8e-05 4.3e-06 7.4e-06 1.3e-06
5 PL gene expression LOC108351432 0.31 0.08 0.0e+00 0.4 0.41 0.41 0.41 7.3e-47 1.0e-48 4.8e-48 2.2e-48
6 IL gene expression LOC108351432 0.6 0.11 1.9e-10 0.24 0.37 0.31 0.35 1.6e-06 7.7e-10 3.2e-08 2.8e-09
7 BLA intron excision ratio chr7_29592818_29601491 0.08 0.05 2.6e-03 0.06 0.04 0.02 0.04 5.9e-04 2.3e-03 3.3e-02 2.2e-03
8 LHb gene expression LOC108351432 0.62 0.14 5.5e-05 0.09 0.04 0.13 0.12 4.3e-03 4.6e-02 4.8e-04 1.0e-03
9 NAcc intron excision ratio chr7_29592818_29601491 0.1 0.06 1.5e-03 0.01 0.03 0.01 0.01 1.8e-02 3.5e-04 2.0e-02 1.3e-02
10 NAcc gene expression LOC108351432 0.27 0.09 0.0e+00 0.19 0.17 0.17 0.19 7.8e-22 8.5e-20 2.4e-19 4.9e-22
11 pVTA intron excision ratio chr7_29592818_29601491 0.1 0.07 7.8e-03 0.02 0.04 0.01 0.02 3.2e-02 8.6e-03 7.7e-02 4.8e-02
12 BLA intron excision ratio chr7_29600910_29601491 0.12 0.06 1.3e-04 0.07 0.07 0.05 0.06 1.0e-04 8.1e-05 1.6e-03 3.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.20.70.40.00.0-0.00.20.30.80.5-0.60.2-0.60.8
Area under the delay curve3.23.48.7-1.01.7-1.4-1.5-1.7-2.4-1.62.91.1-2.02.3-1.4
BMI with tail1.34.111.7-2.6-0.40.30.6-0.8-1.9-3.41.62.7-0.63.1-2.3
BMI without tail1.53.08.8-3.0-1.91.72.01.20.3-2.20.52.50.91.6-0.5
Body weight3.414.127.2-5.2-5.14.84.93.91.9-4.20.44.03.12.50.2
Weight adjusted by age0.60.62.21.5-0.50.50.10.50.20.6-1.0-1.40.6-0.60.8
Bone surface0.20.41.3-0.90.20.10.0-0.3-0.6-0.71.20.8-0.30.7-0.3
Bone volume0.10.21.1-0.50.10.00.1-0.2-0.5-0.31.10.4-0.20.40.0
Breakpoint value in progressive ratio session1.51.73.20.91.8-1.7-1.4-1.8-1.80.31.0-0.5-1.50.8-1.0
Number of licking bursts0.30.31.5-0.6-0.10.20.2-0.4-0.6-1.20.40.6-0.10.7-0.5
Context. condit. distance diff. score0.40.52.5-1.6-0.30.40.40.40.4-0.6-0.11.40.10.7-0.5
Locomotion velocity, session 11.31.56.62.60.5-0.6-0.9-0.3-0.41.5-0.4-2.3-0.2-1.00.7
Locomotion distance, session 10.20.21.01.00.4-0.2-0.4-0.3-0.6-0.3-0.1-0.9-0.40.2-0.1
Locomotion velocity, session 20.40.51.60.5-0.3-0.3-0.10.71.31.1-0.6-0.70.2-1.00.6
Locomotion distance, session 20.10.21.20.00.1-0.00.2-0.2-0.6-1.10.2-0.1-0.20.7-0.3
Locomotion velocity, session 30.40.41.30.90.2-0.2-0.60.50.71.2-0.1-1.1-0.1-0.60.7
Locomotion distance, session 30.40.41.4-0.70.4-0.1-0.1-0.2-0.5-1.20.30.7-0.51.2-0.7
Stereotopy head waving bouts, day 30.60.72.11.10.1-0.3-0.60.20.71.4-0.0-1.30.1-1.20.9
Stereotopy head waving duration, day 30.91.13.51.4-0.1-0.2-0.60.50.91.9-0.0-1.60.3-1.61.2
Locomotion velocity, session 70.20.21.60.50.00.20.30.10.1-0.5-1.2-0.40.00.3-0.2
Locomotion distance, session 70.10.20.30.10.6-0.3-0.1-0.4-0.4-0.5-0.4-0.0-0.40.6-0.4
Stereotopy head waving bouts, day 71.82.05.22.0-0.90.50.41.11.31.8-1.2-2.31.0-1.71.6
Stereotopy head waving duration, day 70.80.93.31.7-0.40.1-0.10.50.51.2-0.3-1.80.5-1.11.0
Locomotion velocity, session 80.50.51.50.1-0.70.50.31.01.11.2-0.5-0.20.6-0.90.7
Locomotion distance, session 80.71.13.4-1.7-0.60.91.00.60.1-1.8-0.11.30.21.5-0.5
Degree of sensitization distance0.10.10.30.10.4-0.4-0.3-0.5-0.30.30.20.1-0.3-0.1-0.2
Degree of sensitization stereotypy0.70.72.31.5-0.3-0.1-0.10.40.81.2-0.7-1.50.3-1.00.7
Conditioned locomotion0.00.00.2-0.2-0.0-0.1-0.20.00.4-0.1-0.00.2-0.10.0-0.2
Cocaine response after cond. corrected0.30.42.1-1.1-0.10.00.1-0.1-0.3-0.41.51.00.00.1-0.1
Cocaine response after cond. not corrected0.30.41.7-1.0-0.20.20.2-0.0-0.4-0.41.31.00.10.20.0
Cocaine response before conditioning0.10.10.30.5-0.10.40.10.1-0.10.2-0.6-0.40.1-0.10.2
Saline control response0.60.81.40.1-1.21.01.21.11.10.5-0.6-0.31.1-0.71.0
Bone: connectivity density0.30.52.00.60.10.10.00.30.81.4-0.1-0.70.4-1.20.9
Bone: cortical apparent density0.30.41.5-0.0-0.80.80.70.70.8-0.3-1.2-0.20.60.10.1
Bone: cortical area0.60.92.5-1.4-0.00.40.5-0.2-1.1-1.21.61.2-0.21.2-0.2
Bone: cortical porosity0.20.31.10.1-0.2-0.1-0.00.30.40.81.1-0.20.2-0.70.7
Bone: cortical porosity0.10.21.6-0.00.0-0.1-0.00.1-0.10.11.3-0.10.0-0.20.4
Bone: cortical thickness0.10.20.7-0.4-0.30.60.80.4-0.20.10.80.10.40.00.8
Bone: cortical thickness0.30.30.90.50.7-0.7-0.6-0.6-0.50.50.9-0.4-0.3-0.20.1
Bone: cortical tissue density0.30.41.80.0-0.80.80.70.80.8-0.2-1.3-0.20.60.00.1
Condit. Reinf. active minus inactive responses1.11.25.32.31.0-0.5-1.0-0.9-1.10.7-0.4-1.9-0.5-0.30.1
Condit. Reinf. active-inactive response ratio1.01.02.81.71.1-0.8-1.2-1.2-1.50.10.4-1.2-0.80.2-0.4
Condit. Reinf. active responses1.31.77.32.71.2-0.8-0.9-0.9-1.11.2-0.5-2.2-0.5-0.80.3
Condit. Reinf. inactive responses0.50.62.11.50.8-0.7-0.5-0.5-0.31.1-0.3-1.2-0.4-0.80.2
Incentive salience index mean1.11.37.02.60.40.2-0.2-0.3-0.90.8-0.9-2.40.1-0.70.7
Condit. Reinf. lever presses0.60.83.61.9-0.00.60.40.2-0.40.6-0.8-1.90.4-0.50.9
Condit. Reinf. active minus inactive responses0.50.63.01.70.7-0.5-0.4-0.5-0.60.4-0.8-1.5-0.2-0.2-0.1
Condit. Reinf. active-inactive response ratio0.40.41.61.30.2-0.1-0.00.10.00.8-0.4-1.20.3-0.70.6
Condit. Reinf. active responses0.40.51.61.20.8-0.6-0.5-0.7-0.7-0.1-0.8-0.9-0.40.3-0.6
Condit. Reinf. inactive responses0.60.71.50.41.0-0.9-1.1-1.2-1.0-0.40.10.1-1.10.8-1.2
Condit. Reinf. lever presses0.30.41.81.30.1-0.20.2-0.00.20.4-1.1-1.20.2-0.40.1
Condit. Reinf. lever reinforcers received0.40.61.11.00.9-0.6-0.6-0.9-0.9-0.5-0.8-0.7-0.60.6-0.9
Conditioned reinforcement - actives1.51.52.40.6-1.51.61.31.51.20.5-1.3-0.91.5-1.11.4
Conditioned reinforcement - inactives1.21.32.30.6-1.51.30.91.51.20.9-0.7-1.01.3-0.91.5
Conditioned locomotion1.41.73.2-0.2-1.61.71.41.81.6-0.2-1.5-0.11.6-1.01.2
Patch foraging indifference point 0 sec0.10.10.3-0.1-0.20.10.20.40.50.50.3-0.20.3-0.10.4
Patch foraging indifference point AUC0.60.71.40.2-1.00.90.91.01.00.5-0.2-0.51.1-0.91.2
Delay disc. indifference point, 0s delay0.40.51.41.20.6-0.7-0.6-0.5-0.80.20.7-1.1-0.60.5-0.0
Delay disc. indifference point, 16s delay5.25.310.5-1.81.9-1.5-1.6-2.1-2.8-2.43.22.0-2.33.1-2.2
Delay disc. indifference point, 2s delay0.10.10.6-0.00.2-0.0-0.2-0.1-0.6-0.30.40.0-0.40.8-0.1
Delay disc. indifference point, 24s delay2.01.95.6-1.90.9-0.7-0.9-0.9-1.3-1.12.41.7-1.31.7-1.0
Delay disc. indifference point, 4s delay0.30.31.50.00.4-0.4-0.4-0.5-0.8-0.31.20.1-0.40.3-0.1
Delay disc. indifference point, 8s delay3.73.812.0-1.01.9-1.8-1.9-1.9-2.2-1.33.51.1-2.12.0-1.4
Indifference point function ln k0.60.81.6-0.90.7-0.6-0.6-0.9-0.8-1.00.51.2-0.81.1-1.3
Indifference point function log k0.60.81.6-0.90.7-0.6-0.6-0.9-0.8-1.00.51.2-0.81.1-1.3
Patch foraging total patch changes 0 sec0.10.10.20.0-0.2-0.00.10.40.50.50.4-0.20.3-0.10.4
Patch foraging total patch changes 12 sec1.41.83.51.0-1.31.41.71.40.90.9-0.6-1.41.9-1.31.8
Patch foraging total patch changes 18 sec2.12.74.40.3-2.01.71.92.12.10.9-1.5-0.82.0-1.41.8
Patch foraging total patch changes 24 sec1.31.63.0-0.1-1.71.51.71.71.40.6-0.7-0.31.7-0.91.4
Patch foraging total patch changes 6 sec0.10.10.3-0.1-0.30.30.30.30.20.30.4-0.10.5-0.20.3
Patch foraging time to switch 0 sec0.10.10.20.1-0.30.20.30.30.40.1-0.5-0.20.3-0.30.2
Patch foraging water rate 0 sec0.50.82.9-0.9-0.40.80.80.2-0.9-1.70.30.80.21.5-0.5
Patch foraging water rate 12 sec0.91.33.3-1.1-1.71.51.81.21.0-0.7-0.60.71.4-0.20.6
Patch foraging water rate 18 sec0.30.41.0-0.50.4-0.4-0.3-0.6-0.7-0.90.40.7-0.61.0-1.0
Patch foraging water rate 24 sec0.91.34.5-1.5-0.81.21.20.7-0.2-2.1-0.21.30.31.5-0.6
Patch foraging water rate 6 sec1.52.25.4-2.0-1.71.61.91.10.2-2.3-0.51.70.91.5-0.4
Seeking ratio, delayed vs. immediate footshock0.20.20.90.80.1-0.1-0.3-0.0-0.20.60.4-0.9-0.1-0.40.7
Distance traveled before self-admin0.10.10.20.40.00.10.0-0.0-0.40.4-0.0-0.4-0.00.10.2
Distance traveled after self-admin1.01.12.9-0.70.8-0.6-0.7-0.7-1.3-1.51.10.7-1.01.7-1.0
Extensor digitorum longus weight0.20.83.9-1.40.2-0.3-0.1-0.3-0.6-0.82.01.3-0.40.8-0.5
Bone: elastic displacement1.82.04.21.41.9-1.8-2.0-1.6-1.21.61.4-0.9-1.2-0.7-0.1
Bone: elastic work1.11.42.90.61.6-1.5-1.7-1.2-0.91.51.7-0.3-1.1-0.60.1
Bone: endosteal estimation3.06.611.2-3.01.6-1.7-1.4-2.2-2.2-3.42.53.2-2.33.3-3.1
Bone: endosteal perimeter2.55.113.3-3.40.4-0.0-0.0-1.0-1.8-3.62.03.5-1.13.1-2.3
Epididymis fat weight0.71.74.8-1.5-1.31.51.40.90.4-2.2-1.31.30.61.4-0.7
Delta time in closed arm before/after self-admin0.20.21.3-0.30.10.3-0.0-0.3-0.6-1.20.10.4-0.10.3-0.4
Delta time in open arm before/after self-admin0.60.61.61.10.8-1.3-0.8-0.7-0.10.90.7-0.9-0.5-0.40.0
Diff in mean of infusions in LGA sessions0.80.92.81.71.1-1.0-0.8-1.0-1.01.00.2-1.3-0.5-0.3-0.0
Delay discount exponential model param2.72.97.91.2-1.51.21.31.52.11.5-2.8-1.31.7-2.11.3
Extinction: sum of active levers before priming0.40.40.70.60.8-0.6-0.7-0.8-0.80.30.3-0.4-0.70.2-0.4
Active lever presses in extinction session 61.21.22.80.01.2-0.9-0.6-1.3-1.7-1.40.90.1-1.01.4-1.1
Bone: final force1.62.66.7-1.80.9-0.7-0.7-1.2-1.8-2.12.61.7-1.32.1-1.3
Bone: final moment1.32.16.7-1.40.9-0.7-0.6-1.2-1.8-1.62.61.3-1.11.8-1.0
Food consumed during 24 hour testing period0.70.81.8-0.8-1.11.01.01.11.30.2-1.20.71.0-0.50.2
Glucose0.10.20.40.6-0.40.30.50.20.20.3-0.6-0.60.5-0.50.4
Heart weight1.82.65.5-0.21.6-1.4-1.6-1.6-2.1-1.92.30.4-1.61.7-1.2
Delay discount hyperbolic model param2.22.37.01.0-1.31.11.11.32.01.3-2.7-1.01.6-1.91.1
Intermittent access intake day 1-15 change2.02.03.80.7-1.71.81.71.51.20.4-1.4-0.91.9-1.31.5
Intermittent access intake escalation2.62.54.81.0-1.91.91.91.71.20.4-1.5-1.22.2-1.51.7
Intermittent access intake escalation 20.60.61.20.4-0.90.90.90.90.7-0.4-0.8-0.51.1-0.70.7
Intermitt. access day 1 inactive lever presses0.70.72.41.50.5-0.7-0.9-0.30.01.20.3-1.3-0.1-1.10.5
Intermitt. access day 15 inactive lever presses0.60.71.91.40.7-0.9-1.2-0.3-0.21.30.3-1.2-0.7-0.30.2
Intermitt. access escalation Index0.40.31.10.81.0-0.6-0.5-0.8-0.70.4-0.2-0.5-0.5-0.1-0.4
Intermittent access day 1 total infusions1.21.42.5-1.6-1.51.61.41.41.4-0.2-0.91.21.1-0.00.4
Intermittent access day 15 total infusions2.73.16.1-1.2-2.52.42.32.32.0-0.1-1.40.62.2-0.61.2
Intermittent access terminal intake (last 3 days)1.92.14.5-1.3-2.02.11.91.81.4-0.4-1.20.81.7-0.10.7
Intermittent access total infusions1.82.03.9-1.6-1.92.01.91.81.3-0.4-1.01.11.50.20.6
Intermittent access day 1 locomotion1.11.22.9-1.7-1.41.11.01.41.6-0.5-0.61.20.8-0.10.3
Intermittent access day 15 total locomotion5.25.611.4-0.6-2.92.82.33.33.41.0-2.3-0.22.8-1.92.3
Intermittent access total locomotion2.22.55.2-1.9-2.11.91.72.12.3-0.2-1.21.21.5-0.40.8
Intermittent access standard deviation2.72.85.7-0.6-2.32.42.32.21.6-0.4-1.40.12.2-0.81.4
Left kidney weight1.02.97.1-0.6-2.52.72.22.41.5-1.0-0.80.12.1-0.51.3
Right kidney weight0.51.42.9-1.7-1.51.61.51.40.8-1.20.11.31.00.70.2
Cocaine induced anxiety1.41.63.50.21.6-1.8-1.9-1.5-1.00.01.30.2-1.70.7-1.1
Post-drug Anxiety0.80.92.00.81.3-1.3-1.4-1.0-0.60.90.6-0.5-1.1-0.1-0.4
Baseline Anxiety1.11.11.70.6-1.01.11.11.21.01.1-1.3-0.81.3-1.11.1
Tail length4.513.527.4-3.1-5.24.84.95.24.3-0.4-1.81.54.2-0.92.8
Length with tail5.419.941.8-3.6-6.56.26.06.44.9-1.5-2.01.85.1-0.53.1
Length without tail1.84.09.4-1.0-2.93.12.73.01.8-1.2-0.60.32.4-0.01.5
Times rat made contact with spout2.12.56.4-0.0-2.22.52.21.81.00.1-1.2-0.42.1-1.01.6
Lifetime Intake1.21.32.9-1.7-1.31.61.41.20.8-0.8-0.61.41.00.70.1
Liver weight, left0.20.31.3-0.50.00.20.3-0.2-0.5-1.1-0.30.6-0.00.8-0.6
Liver weight, right0.20.30.70.0-0.80.70.80.70.7-0.3-0.7-0.20.6-0.00.3
Locomotor activity0.81.33.2-0.9-1.31.61.80.9-0.4-1.80.00.60.91.20.0
Locomotor testing distance0.71.13.9-0.8-0.20.60.7-0.3-1.5-2.00.60.8-0.21.8-0.8
Locomotor testing rearing0.10.20.9-0.1-0.50.60.50.3-0.5-0.90.40.10.30.50.1
Locomotion in novel chamber0.10.10.2-0.50.1-0.0-0.3-0.1-0.30.40.30.2-0.30.5-0.0
Locomotion in novel chamber post-restriction0.40.51.4-0.9-0.90.60.40.81.20.6-0.50.60.5-0.50.4
Fecal boli incidents, locomotor time 10.10.10.6-0.7-0.40.10.10.50.8-0.2-0.00.40.1-0.10.1
Change in fecal boli incidents, locomotor task1.71.63.1-0.61.5-1.1-1.0-1.5-1.4-1.20.21.0-1.41.6-1.8
Time >=10cm from walls, locomotor time 11.51.52.60.31.4-1.4-1.5-1.5-1.6-0.71.40.1-1.41.0-1.1
Bouts of movement, locomotor time 10.80.94.10.10.8-1.1-1.0-0.9-1.0-0.62.0-0.0-1.00.5-0.5
Total resting periods, locomotor time 10.50.52.20.70.6-0.9-1.0-0.6-0.7-0.11.5-0.6-0.7-0.0-0.0
Rest time, locomotor task time 11.01.02.91.70.6-0.7-1.5-0.30.11.50.5-1.6-0.2-1.00.6
Distance moved, locomotor task time 10.60.62.20.2-0.81.11.50.60.0-0.3-1.3-0.30.90.00.5
Vertical activity count, locomotor time 10.80.92.8-0.8-0.71.01.70.2-0.7-1.5-0.80.70.51.0-0.4
Time >=10cm from walls, locomotor time 21.71.86.12.5-0.20.20.10.40.11.7-0.7-2.40.8-1.71.5
Bouts of movement, locomotor time 20.50.62.7-0.60.5-0.4-0.4-0.4-0.7-0.91.60.7-0.50.8-0.7
Total resting periods, locomotor time 20.90.93.7-0.40.8-0.7-0.8-0.8-1.1-0.91.90.6-0.81.0-0.9
Rest time, locomotor task time 21.61.83.30.31.5-1.6-1.8-1.7-1.5-0.71.50.2-1.51.0-1.4
Distance moved, locomotor task time 22.02.33.61.2-1.51.41.51.61.21.4-1.9-1.51.7-1.61.7
Vertical activity count, locomotor time 22.32.56.20.2-2.12.12.51.91.10.1-1.6-0.72.1-0.91.6
Light reinforcement 10.10.21.2-0.2-0.40.40.40.40.5-0.1-1.10.30.40.1-0.2
Light reinforcement 20.81.02.7-1.50.7-1.0-0.6-0.8-0.1-0.90.71.6-0.91.0-1.4
Bone: marrow area3.06.411.0-3.01.5-1.6-1.4-2.1-2.1-3.32.43.2-2.23.3-3.1
Bone: maximum diameter1.52.87.2-2.50.00.20.4-0.6-1.4-2.71.52.5-0.72.4-1.6
Bone: maximum force1.62.87.0-1.61.3-1.1-1.0-1.4-1.9-1.72.61.7-1.62.1-1.4
Bone: maximum moment1.32.37.1-1.11.3-1.1-1.0-1.4-2.0-1.32.71.2-1.51.7-1.1
Mean time between licks in bursts0.20.21.00.10.20.1-0.1-0.3-1.0-0.60.60.0-0.20.6-0.3
Mean num. licks in bursts0.70.81.30.7-0.70.90.71.00.81.1-1.0-0.91.0-1.01.2
Cd content in liver1.01.03.2-1.00.4-0.4-0.1-0.7-1.1-1.81.21.0-0.51.5-1.1
Co content in liver1.61.93.8-0.7-1.81.92.01.71.50.2-1.30.31.7-0.71.0
Cu content in liver0.70.81.6-1.2-1.20.81.31.01.1-0.2-0.51.00.9-0.20.1
Fe content in liver1.01.22.9-1.70.4-0.4-0.3-0.4-0.5-1.71.11.6-0.81.5-1.1
K content in liver4.14.18.30.8-2.01.51.72.12.92.3-2.0-1.32.1-2.52.2
Mg content in liver0.90.92.00.5-1.00.70.81.01.40.9-1.2-0.71.0-1.10.9
Mn content in liver0.20.20.7-0.6-0.50.50.80.30.3-0.6-0.50.50.40.2-0.2
Na content in liver0.60.61.60.1-0.80.60.70.81.30.8-1.0-0.30.8-0.90.7
Rb content in liver0.50.62.4-0.7-0.6-0.10.00.61.51.20.30.50.4-1.10.6
Se content in liver0.40.51.8-0.60.0-0.10.2-0.10.2-1.3-1.10.7-0.21.0-1.1
Sr content in liver0.60.51.81.20.2-0.1-0.20.2-0.21.00.5-1.30.1-0.61.1
Zn content in liver0.60.61.20.1-1.00.80.81.11.10.7-0.7-0.20.9-0.70.7
Bone: minimum diameter1.73.39.4-2.8-0.20.71.0-0.3-1.5-3.11.52.6-0.32.7-1.4
Time in familiar zone, hab. session 10.10.10.30.20.5-0.6-0.5-0.4-0.3-0.1-0.1-0.0-0.50.3-0.5
Time in novel zone, hab. session 10.80.81.5-1.00.6-0.7-0.7-0.9-0.8-0.91.21.1-0.80.9-1.0
Total zone transitions, hab. session 10.50.72.01.3-0.51.01.10.5-0.4-0.6-0.9-1.40.70.10.7
Total locomotion distance, hab. session 11.11.64.42.0-0.91.51.10.90.10.1-1.6-2.11.1-0.51.2
Locomotion velocity, hab. session 12.02.86.72.4-1.32.01.61.30.30.4-2.1-2.61.5-0.81.7
Time in familiar zone, hab. session 20.10.10.40.20.3-0.3-0.3-0.5-0.60.10.2-0.0-0.40.2-0.3
Time in novel zone, hab. session 20.60.61.0-0.30.8-0.9-0.9-0.7-0.6-0.81.00.4-0.90.7-0.8
Total zone transitions, hab. session 20.50.62.21.00.7-0.1-0.3-0.6-1.5-1.00.2-0.9-0.61.1-0.3
Total locomotion distance, hab. session 20.50.72.51.60.40.3-0.0-0.5-1.4-0.7-0.3-1.4-0.20.6-0.1
Locomotion velocity, hab. session 20.50.72.51.60.40.40.0-0.4-1.4-0.7-0.5-1.4-0.20.6-0.1
Novel to familiar place preference ratio1.81.93.30.8-1.20.90.91.31.81.8-1.8-1.01.3-1.81.3
Novelty place preference1.91.94.11.2-1.00.70.71.21.62.0-1.8-1.21.2-1.91.4
Time in novel zone, NPP test1.31.32.70.9-0.90.60.61.01.41.6-1.5-1.01.0-1.61.1
Total zone transitions, NPP test0.50.72.5-0.10.7-0.2-0.1-0.5-1.3-1.60.70.1-0.71.4-0.5
Total locomotion distance, NPP test0.30.40.90.9-0.10.70.60.2-0.6-0.7-0.7-0.90.20.40.2
Locomotion velocity, NPP test0.30.41.11.0-0.10.70.50.3-0.3-0.4-1.0-1.00.20.20.4
Intraocular pressure0.20.30.5-0.30.7-0.7-0.5-0.7-0.5-0.20.30.4-0.60.3-0.6
Delta distance traveled before/after self-admin0.40.41.8-0.60.3-0.3-0.3-0.3-0.5-1.40.70.5-0.40.9-0.5
Delta ambulatory time before/after self-admin1.01.02.2-0.51.0-1.0-1.0-0.9-0.9-1.51.10.5-1.11.2-1.0
Parametrial fat weight1.32.53.8-0.11.8-1.9-1.6-1.9-2.0-1.01.50.4-2.01.7-1.7
Pavlov. Cond. lever latency1.72.15.7-2.40.3-0.6-0.4-0.7-0.6-2.01.22.4-0.91.8-1.7
Pavlov. Cond. magazine entry latency0.40.52.01.40.6-0.3-0.3-0.6-0.9-0.2-0.5-1.2-0.40.2-0.2
Pavlov. Cond. change in total contacts0.30.31.11.0-0.10.30.5-0.1-0.30.0-1.0-1.00.4-0.20.2
Pavlov. Cond. index score0.81.05.32.30.30.1-0.1-0.1-0.50.9-0.7-2.10.1-0.70.7
Pavlov. Cond. latency score1.11.46.12.50.10.20.00.1-0.21.2-0.9-2.40.4-1.11.0
Pavlov. Cond. lever contacts1.92.35.72.3-0.61.00.90.90.61.8-1.5-2.41.2-1.71.8
Pavlov. Cond. magazine entry number0.30.41.8-1.3-0.40.20.30.50.80.10.41.20.3-0.20.2
Pavlov. Cond. intertrial magazine entries2.42.85.3-1.91.1-1.0-0.9-1.3-1.6-2.31.72.1-1.42.2-2.0
Pavlov. Cond. lever-magazine prob. diff.0.60.84.22.00.4-0.0-0.2-0.3-0.80.5-0.4-1.9-0.0-0.40.5
Pavlov. Cond. response bias0.91.04.12.0-0.20.60.40.3-0.10.7-1.2-2.00.6-0.80.8
Pavlov. Cond. lever latency0.30.30.5-0.7-0.60.50.30.60.70.60.50.50.5-0.70.7
Pavlov. Cond. magazine entry latency0.30.41.50.2-0.60.90.80.60.3-0.0-1.2-0.30.6-0.30.4
Pavlov. Cond. change in total contacts0.81.15.3-1.0-0.10.60.8-0.0-0.8-2.3-0.50.9-0.11.8-1.0
Pavlov. Cond. index score0.30.41.6-0.1-0.40.70.80.3-0.0-1.0-1.30.10.30.6-0.3
Pavlov. Cond. latency score0.20.31.7-0.0-0.30.60.60.20.0-0.8-1.30.00.20.5-0.3
Pavlov. Cond. lever contacts0.50.71.90.40.7-0.5-0.3-1.0-1.3-1.4-0.1-0.2-0.71.3-1.1
Pavlov. Cond. magazine entry number0.40.51.80.30.4-0.8-0.8-0.20.31.41.3-0.3-0.2-0.80.5
Pavlov. Cond. intertrial magazine entries0.10.10.30.60.2-0.3-0.2-0.2-0.20.60.3-0.30.0-0.50.1
Pavlov. Cond. lever-magazine prob. diff.0.40.52.0-0.0-0.61.01.00.50.2-0.8-1.4-0.10.60.3-0.0
Pavlov. Cond. response bias0.40.52.30.20.20.00.2-0.6-1.1-1.5-0.3-0.1-0.31.2-0.9
Time in closed arm before self-admin0.20.20.5-0.1-0.60.70.60.70.40.3-0.50.10.5-0.10.4
Time in closed arm after self-admin0.40.41.2-0.90.20.0-0.2-0.4-0.5-1.10.31.1-0.40.7-0.8
Time in open arm before self-admin0.10.10.2-0.30.3-0.1-0.2-0.2-0.2-0.50.10.3-0.20.1-0.2
Time in open arm after self-admin0.30.41.11.00.6-0.9-0.4-0.4-0.20.70.4-1.0-0.3-0.40.2
Bone: periosteal estimation2.55.19.5-3.11.0-0.9-0.6-1.5-2.0-3.02.53.1-1.73.1-2.3
Bone: periosteal perimeter1.93.26.9-2.50.6-0.3-0.1-1.0-1.8-2.62.02.5-1.12.5-1.7
Bone: post-yield work0.20.30.8-0.90.1-0.2-0.0-0.2-0.1-0.80.30.9-0.50.6-0.6
Progressive ratio test 1 active lever presses3.53.67.4-2.1-2.72.72.52.42.0-0.4-1.31.42.0-0.21.0
Progressive ratio test 1 breakpoint3.03.16.3-1.9-2.52.52.32.21.7-0.5-1.31.21.9-0.10.9
Progressive ratio test 1 inactive lever presses0.40.41.20.3-0.70.70.40.70.81.1-0.3-0.50.6-0.60.7
Progressive ratio test 2 active lever presses2.62.85.7-0.6-2.32.42.12.21.80.3-1.40.12.1-0.81.4
Progressive ratio test 2 breakpoint2.93.26.8-0.6-2.52.62.42.31.80.6-1.5-0.02.3-0.81.6
Progressive ratio test 2 inactive lever presses0.91.01.60.5-1.11.10.71.21.30.9-0.8-0.81.1-1.01.2
Incentive Sensitization - Responses3.33.45.80.1-2.42.42.32.41.90.9-1.5-0.62.3-1.42.0
Incentive Sensitization - Breakpoint3.23.35.40.1-2.32.32.22.31.91.0-1.5-0.62.3-1.41.9
Sum of active levers in priming session hrs 5-60.50.42.11.50.10.20.3-0.1-0.70.1-0.5-1.40.4-0.30.4
Progressive ratio0.80.92.40.01.4-1.2-1.6-0.9-0.80.60.60.0-1.40.8-0.6
Food seeking constrained by brief footshock1.11.42.8-0.4-1.61.61.51.71.30.3-1.0-0.11.4-0.51.1
Seeking ratio, punishment vs. effort1.01.22.8-0.1-1.61.51.71.31.0-0.3-0.8-0.11.5-0.80.9
Retroperitoneal fat weight0.41.42.7-1.3-1.41.71.51.20.3-1.5-1.10.90.71.5-0.3
Reaction time number correct0.20.30.9-0.00.4-0.7-0.5-0.6-0.8-0.41.0-0.0-0.60.6-0.3
Reaction time mean minus median0.30.41.01.00.5-0.7-0.8-0.3-0.10.40.3-0.9-0.4-0.80.3
Reaction time mean minus median AUC0.50.62.11.50.1-0.4-0.50.00.20.7-0.3-1.30.1-1.30.7
Reaction time num false alarms0.30.31.30.70.4-0.6-0.5-0.30.21.20.5-0.6-0.1-0.90.3
Reaction time num false alarms AUC0.40.61.10.90.8-1.0-0.9-0.7-0.31.10.9-0.6-0.5-0.60.0
Reaction time trials correct on left0.20.30.9-0.00.4-0.7-0.5-0.6-0.8-0.41.0-0.0-0.60.6-0.3
Reaction time trials on left0.30.41.10.00.4-0.8-0.6-0.7-0.9-0.41.0-0.0-0.70.6-0.3
Reaction time mean0.30.41.3-0.20.3-0.3-0.4-0.6-1.0-1.10.70.4-0.70.8-0.7
Reaction time mean AUC0.20.21.0-0.30.1-0.1-0.2-0.3-0.6-1.00.50.4-0.40.5-0.5
Median of all reaction times0.50.62.4-0.70.0-0.0-0.1-0.4-0.9-1.50.60.8-0.61.2-1.0
Reaction time omissions2.02.75.30.12.1-2.2-2.2-2.3-1.8-0.41.60.4-2.00.6-1.6
Reaction time false alarm rate0.20.30.90.60.6-0.6-0.6-0.40.21.00.2-0.3-0.2-0.7-0.0
Reaction time premature initiation rate0.40.51.50.10.7-0.4-0.2-0.9-1.2-0.70.5-0.0-0.61.1-0.7
Reaction time premature initiations0.20.31.10.30.4-0.3-0.1-0.6-1.1-0.50.6-0.3-0.40.8-0.3
Std. dev. reaction times0.40.51.21.00.7-0.9-1.1-0.7-0.60.20.6-0.8-0.7-0.5-0.0
Reaction time trials completed0.30.41.10.00.4-0.8-0.6-0.7-0.9-0.41.0-0.0-0.70.6-0.3
Reaction time trials AUC0.30.41.2-0.10.4-0.7-0.5-0.6-0.9-0.51.10.1-0.70.7-0.4
Run reversals in cocaine runway, females0.10.10.4-0.20.00.2-0.10.1-0.20.10.60.0-0.10.40.2
Run reversals in cocaine runway, males0.10.10.50.6-0.20.10.20.10.2-0.1-0.7-0.60.4-0.40.2
Latency to leave start box in cocaine runway0.10.10.20.5-0.20.20.3-0.0-0.3-0.2-0.2-0.40.2-0.10.1
Latency to leave start box in cocaine runway, F0.30.40.80.90.5-0.4-0.3-0.6-0.7-0.7-0.8-0.6-0.30.3-0.6
Latency to leave start box in cocaine runway, M1.71.62.9-0.7-1.71.61.61.61.50.6-0.10.21.6-1.21.4
Std. dev. time between licks in bursts1.61.94.60.61.7-1.3-1.5-1.7-2.2-0.81.2-0.2-1.51.4-1.2
Total sessions with >9 infusions1.21.35.3-2.3-0.80.80.90.50.5-1.50.02.00.31.0-0.6
Short access day 1 total inactive lever presses0.00.00.1-0.20.10.1-0.10.00.10.0-0.10.30.10.2-0.1
Short access day 10 total inactive lever presses2.12.37.92.81.4-1.2-1.8-0.8-0.42.0-0.3-2.2-0.6-1.60.4
Short access day 1 total infusions0.60.62.2-1.5-0.50.90.90.3-0.1-0.7-0.31.40.40.9-0.5
Short access day 10 total infusions1.41.52.8-1.7-1.61.71.71.40.9-1.1-0.51.31.20.60.2
Short access total infusions0.80.91.9-1.3-1.01.41.20.80.3-0.9-0.51.00.80.8-0.1
Short access day 1 locomotion0.91.02.0-0.6-1.41.41.41.10.90.3-0.80.31.2-0.50.8
Short access day 10 total locomotion0.10.10.5-0.7-0.20.20.20.30.3-0.6-0.20.60.00.3-0.1
Short access total locomotion1.41.42.6-0.6-1.61.61.61.61.30.0-1.10.11.5-0.51.0
One hour access (0.3 mA shock)2.12.55.8-0.4-2.12.42.02.21.60.1-1.5-0.11.9-0.41.4
Compulsive drug intake0.90.92.61.61.0-0.8-1.2-0.7-0.41.20.1-1.5-0.6-0.80.3
One hour access (shock baseline)2.73.16.7-0.9-2.42.62.42.51.80.1-1.60.42.1-0.31.4
Social response proportion0.80.92.9-1.10.1-0.1-0.2-0.4-0.9-1.71.41.0-0.51.4-0.8
Social responses0.20.21.10.5-0.00.30.2-0.1-1.1-0.60.7-0.60.00.50.2
Social time0.30.40.80.3-0.80.80.80.60.2-0.10.3-0.50.9-0.70.9
Soleus weight0.72.14.8-1.41.0-0.9-0.8-1.3-1.6-1.52.21.5-1.21.8-1.4
Bone: stiffness2.03.29.0-2.20.5-0.60.0-0.9-1.6-3.02.32.0-1.12.7-1.6
Tibialis anterior weight1.13.811.0-1.11.8-1.7-1.6-1.9-2.3-1.63.31.4-1.92.0-1.7
Time to tail flick, vehicle, before self-admin4.14.28.6-0.3-2.62.72.92.51.90.0-2.1-0.22.7-1.51.8
Time to tail flick, vehicle, after self-admin1.11.22.21.51.4-1.4-1.4-1.2-1.20.20.7-1.1-1.10.3-0.5
Time to tail flick, test, before self-admin0.70.62.1-1.40.1-0.10.1-0.1-0.1-1.30.71.3-0.41.0-0.7
Time to tail flick, test, after self-admin0.00.00.1-0.10.00.10.20.1-0.1-0.3-0.20.10.10.10.0
Delta time to tail flick, vehicle, before/after SA4.14.08.11.42.7-2.7-2.9-2.5-2.10.31.6-0.7-2.51.1-1.5
Delta time to tail flick, test, before/after SA0.70.61.81.4-0.20.20.20.40.31.0-0.9-1.30.6-0.90.9
Tibia length2.77.716.7-3.3-3.74.04.13.31.6-2.5-1.12.32.71.20.8
Ambulatory time before self-admin0.20.20.60.2-0.40.30.40.40.40.8-0.3-0.20.4-0.40.5
Ambulatory time after self-admin0.70.82.3-0.70.6-0.5-0.6-0.5-1.0-1.30.90.7-0.81.5-0.9
Bone: tissue strength0.20.20.6-0.40.0-0.10.3-0.2-0.5-0.70.60.3-0.20.7-0.1
Total heroin consumption1.21.43.10.51.6-1.3-1.1-1.7-1.8-0.30.7-0.1-1.31.0-1.2
Bone: trabecular number0.20.31.20.50.1-0.0-0.30.10.41.10.2-0.60.1-0.80.7
Bone: trabecular spacing0.10.20.70.50.1-0.0-0.10.0-0.00.8-0.5-0.40.1-0.50.4
Bone: trabecular thickness0.20.20.40.2-0.60.40.50.50.50.6-0.2-0.30.5-0.50.6
Bone: trabecular tissue density0.10.20.70.3-0.60.20.10.40.6-0.3-0.8-0.50.20.10.0
Water consumed over 24 hours0.81.01.9-1.3-1.31.11.41.01.1-0.3-0.11.11.1-0.30.2
Number of responses in last shaping day0.50.61.5-0.4-1.01.21.00.90.60.4-0.70.10.8-0.10.7