Hub : Genes

LOC108351405

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr7_9377264_9380456 0.08 0.06 7.4e-03 0.04 0.03 0.04 0.03 6.8e-03 1.7e-02 7.1e-03 1.7e-02
2 pVTA intron excision ratio chr7_9382946_9387088 0.18 0.11 6.0e-05 0.1 0.09 0.08 0.08 4.3e-05 8.5e-05 3.5e-04 3.1e-04
3 BLA gene expression LOC108351405 0.16 0.09 1.4e-10 0.15 0.2 0.2 0.19 2.0e-08 8.3e-11 8.8e-11 1.3e-10
4 Adipose gene expression LOC108351405 0.14 0.09 3.5e-14 0.11 0.1 0.11 0.11 2.9e-12 1.1e-11 5.6e-12 8.6e-12
5 PL gene expression LOC108351405 0.09 0.05 4.9e-13 0.09 0.11 0.11 0.11 2.7e-10 2.1e-12 2.6e-12 4.8e-12
6 NAcc gene expression LOC108351405 0.08 0.05 2.2e-11 0.09 0.1 0.1 0.1 8.7e-11 6.1e-12 5.6e-12 3.3e-12
7 Liver gene expression LOC108351405 0.16 0.09 0.0e+00 0.16 0.17 0.17 0.17 8.4e-18 3.4e-18 3.6e-18 3.4e-18
8 LHb gene expression LOC108351405 0.11 0.08 7.5e-03 0.05 0.05 0.01 0.05 2.1e-02 2.4e-02 1.7e-01 2.9e-02
9 RMTg gene expression LOC108351405 0.15 0.1 2.3e-03 0.04 0.05 0.05 0.04 2.3e-02 2.1e-02 2.2e-02 3.8e-02
10 pVTA gene expression LOC108351405 0.15 0.1 8.6e-07 0.16 0.16 0.16 0.16 1.5e-07 2.3e-07 2.8e-07 1.7e-07
11 Brain gene expression LOC108351405 0.12 0.09 2.4e-09 0.07 0.08 0.09 0.08 8.9e-07 5.5e-08 1.5e-08 4.3e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.41.11.0-1.0-0.11.10.2-0.20.5-0.80.7-0.60.1
Area under the delay curve2.32.43.0-1.61.51.6-1.21.71.51.7-1.61.7-1.6-1.1
BMI with tail6.922.423.8-4.84.84.8-4.94.84.94.7-4.54.5-4.5-4.9
BMI without tail2.85.89.2-3.02.82.5-2.72.42.52.1-1.92.0-2.2-2.2
Body weight1.25.16.1-2.52.32.4-2.32.32.32.2-2.12.2-2.3-2.1
Weight adjusted by age0.50.61.8-1.31.00.8-0.90.70.70.3-0.30.4-0.5-0.6
Bone surface0.81.44.42.0-2.0-0.92.1-0.4-0.90.1-0.50.3-0.20.8
Bone volume0.81.34.51.9-2.0-0.82.1-0.4-0.90.1-0.50.4-0.30.9
Breakpoint value in progressive ratio session5.15.67.12.1-1.9-2.52.0-2.6-2.3-2.72.6-2.62.71.9
Number of licking bursts0.20.20.6-0.70.80.3-0.60.20.3-0.10.1-0.10.0-0.5
Context. condit. distance diff. score0.30.40.7-0.80.70.6-0.60.60.70.6-0.60.5-0.6-0.3
Locomotion velocity, session 10.80.91.91.2-1.4-0.91.3-0.8-0.9-0.50.5-0.40.51.0
Locomotion distance, session 10.40.51.91.4-1.2-0.61.1-0.4-0.50.1-0.10.1-0.10.3
Locomotion velocity, session 24.35.09.13.0-2.8-2.42.5-2.2-2.3-1.71.6-1.71.72.3
Locomotion distance, session 21.92.76.82.6-2.3-1.82.0-1.5-1.6-1.11.0-0.91.01.3
Locomotion velocity, session 36.37.38.22.5-2.5-2.82.5-2.8-2.8-2.72.8-2.82.92.9
Locomotion distance, session 30.00.00.1-0.30.10.1-0.20.00.10.0-0.0-0.1-0.00.2
Stereotopy head waving bouts, day 35.16.07.62.8-2.4-2.72.5-2.6-2.5-2.32.3-2.32.32.3
Stereotopy head waving duration, day 36.17.38.22.9-2.6-2.92.7-2.8-2.7-2.62.6-2.62.72.6
Locomotion velocity, session 70.80.92.80.3-1.1-0.71.1-0.7-1.0-0.90.8-0.70.71.7
Locomotion distance, session 70.20.21.1-1.00.50.6-0.60.50.40.1-0.10.2-0.20.2
Stereotopy head waving bouts, day 70.10.10.30.6-0.5-0.30.5-0.1-0.20.2-0.20.1-0.10.2
Stereotopy head waving duration, day 70.30.41.11.0-1.0-0.71.0-0.5-0.6-0.20.1-0.20.20.5
Locomotion velocity, session 80.81.02.41.6-1.5-1.01.4-0.8-0.9-0.40.4-0.40.41.0
Locomotion distance, session 80.10.20.60.8-0.6-0.50.5-0.5-0.4-0.20.2-0.20.20.4
Degree of sensitization distance0.40.40.5-0.60.50.7-0.50.70.60.6-0.60.7-0.7-0.4
Degree of sensitization stereotypy1.71.82.9-1.00.91.3-0.91.41.31.6-1.71.6-1.6-1.2
Conditioned locomotion1.72.03.5-1.91.91.5-1.81.31.51.1-0.91.0-1.0-1.4
Cocaine response after cond. corrected5.86.511.3-3.43.02.7-2.92.62.62.2-1.92.1-2.1-2.1
Cocaine response after cond. not corrected6.16.811.8-3.43.02.8-3.02.62.72.2-1.92.1-2.2-2.1
Cocaine response before conditioning0.60.71.10.8-1.1-0.81.0-0.8-0.9-0.70.7-0.70.71.0
Saline control response0.10.10.2-0.30.50.3-0.40.20.30.2-0.10.2-0.2-0.4
Bone: connectivity density0.30.41.20.4-0.40.30.40.60.30.8-1.11.0-0.9-0.3
Bone: cortical apparent density0.81.01.1-0.81.01.0-1.01.01.01.0-1.11.0-0.9-1.1
Bone: cortical area0.50.71.4-0.50.20.8-0.11.00.71.0-1.21.2-1.2-0.4
Bone: cortical porosity0.60.71.21.0-1.1-0.81.1-0.7-0.9-0.70.6-0.50.40.7
Bone: cortical porosity0.20.20.60.7-0.8-0.30.7-0.1-0.30.1-0.20.2-0.30.2
Bone: cortical thickness1.01.72.3-1.00.91.3-0.91.41.21.4-1.51.5-1.5-1.1
Bone: cortical thickness0.10.10.4-0.60.40.2-0.40.10.0-0.20.3-0.20.20.1
Bone: cortical tissue density0.50.70.8-0.70.90.9-0.80.90.90.8-0.90.8-0.7-0.9
Condit. Reinf. active minus inactive responses4.34.85.52.2-2.1-2.32.0-2.3-2.2-2.22.1-2.32.32.2
Condit. Reinf. active-inactive response ratio2.12.23.01.1-1.2-1.51.1-1.6-1.5-1.61.6-1.71.71.5
Condit. Reinf. active responses3.94.76.92.6-2.4-2.42.2-2.3-2.2-1.91.8-2.02.01.9
Condit. Reinf. inactive responses1.01.23.01.7-1.4-1.21.4-1.0-1.1-0.70.6-0.60.70.7
Incentive salience index mean2.42.84.12.0-1.8-1.91.7-1.8-1.7-1.51.4-1.51.51.6
Condit. Reinf. lever presses0.20.31.31.1-0.8-0.40.7-0.1-0.20.3-0.40.4-0.3-0.1
Condit. Reinf. active minus inactive responses2.02.53.51.1-1.1-1.51.3-1.6-1.6-1.91.9-1.81.91.4
Condit. Reinf. active-inactive response ratio0.20.20.4-0.30.5-0.1-0.4-0.2-0.1-0.50.6-0.50.5-0.3
Condit. Reinf. active responses2.12.93.71.3-1.5-1.61.7-1.7-1.8-1.81.8-1.81.81.9
Condit. Reinf. inactive responses1.41.73.71.0-1.5-1.11.5-1.1-1.4-1.21.2-1.11.21.9
Condit. Reinf. lever presses2.23.04.31.2-1.4-1.71.4-1.8-1.8-1.92.1-1.91.91.6
Condit. Reinf. lever reinforcers received1.52.12.90.9-1.2-1.31.3-1.4-1.5-1.71.7-1.61.61.7
Conditioned reinforcement - actives2.22.22.91.4-1.6-1.51.5-1.5-1.5-1.71.4-1.51.41.3
Conditioned reinforcement - inactives0.50.61.1-1.10.90.8-1.00.70.90.6-0.60.6-0.5-0.5
Conditioned locomotion7.08.49.82.8-2.9-3.02.8-3.0-2.9-3.12.9-2.92.92.6
Patch foraging indifference point 0 sec0.10.20.4-0.30.30.4-0.20.50.40.5-0.50.5-0.6-0.5
Patch foraging indifference point AUC0.80.91.20.8-0.9-0.90.8-1.0-1.0-1.11.0-1.00.90.6
Delay disc. indifference point, 0s delay6.47.110.1-1.71.92.5-2.02.82.63.1-3.23.2-3.2-2.5
Delay disc. indifference point, 16s delay0.10.10.2-0.30.40.3-0.20.40.40.5-0.40.3-0.3-0.3
Delay disc. indifference point, 2s delay5.56.17.7-2.12.12.5-2.12.62.42.7-2.82.7-2.7-2.3
Delay disc. indifference point, 24s delay0.80.81.2-1.10.91.0-0.70.90.90.9-0.70.8-0.8-0.9
Delay disc. indifference point, 4s delay0.91.01.7-0.80.91.0-0.61.11.01.3-1.21.2-1.0-0.6
Delay disc. indifference point, 8s delay1.41.42.6-1.61.31.3-1.21.31.11.1-1.01.1-1.1-0.8
Indifference point function ln k0.20.30.6-0.80.60.6-0.40.60.60.6-0.50.5-0.5-0.2
Indifference point function log k0.20.30.6-0.80.60.6-0.40.60.60.6-0.50.5-0.5-0.2
Patch foraging total patch changes 0 sec0.10.20.2-0.30.40.4-0.20.40.40.4-0.40.4-0.5-0.5
Patch foraging total patch changes 12 sec0.50.61.2-0.91.00.8-1.10.60.80.4-0.40.5-0.6-1.1
Patch foraging total patch changes 18 sec1.11.41.61.2-1.1-1.21.1-1.3-1.2-1.21.2-1.21.20.9
Patch foraging total patch changes 24 sec0.10.10.10.4-0.2-0.30.2-0.3-0.3-0.30.3-0.30.2-0.1
Patch foraging total patch changes 6 sec0.20.30.50.7-0.6-0.60.7-0.6-0.6-0.60.5-0.50.40.3
Patch foraging time to switch 0 sec1.01.62.8-0.30.71.0-0.81.21.31.7-1.61.6-1.7-1.2
Patch foraging water rate 0 sec0.10.21.2-1.10.70.3-0.50.10.1-0.40.3-0.40.40.1
Patch foraging water rate 12 sec1.32.04.7-2.22.01.5-1.81.31.40.9-0.70.8-0.8-1.2
Patch foraging water rate 18 sec0.50.61.5-1.21.20.2-1.0-0.10.1-0.70.9-0.80.9-0.0
Patch foraging water rate 24 sec0.81.23.9-2.01.81.0-1.70.70.90.2-0.00.00.0-0.8
Patch foraging water rate 6 sec0.30.41.1-0.50.1-0.2-0.1-0.5-0.5-0.91.0-0.91.00.5
Seeking ratio, delayed vs. immediate footshock4.65.36.02.4-2.4-2.42.5-2.3-2.4-2.22.1-2.12.12.2
Distance traveled before self-admin0.50.50.8-0.50.40.7-0.50.70.70.7-0.90.9-0.9-0.7
Distance traveled after self-admin0.60.70.90.9-0.9-0.80.9-0.8-0.8-0.80.8-0.70.60.8
Extensor digitorum longus weight5.019.824.4-4.94.84.7-4.84.54.64.2-4.14.1-4.0-4.1
Bone: elastic displacement0.30.30.50.6-0.7-0.50.7-0.5-0.6-0.50.5-0.40.50.4
Bone: elastic work0.20.20.5-0.40.10.5-0.00.60.40.5-0.60.6-0.7-0.1
Bone: endosteal estimation0.20.30.6-0.40.40.6-0.30.60.60.7-0.80.7-0.7-0.3
Bone: endosteal perimeter0.30.71.40.9-1.1-0.81.2-0.7-0.8-0.50.5-0.50.51.1
Epididymis fat weight0.20.40.90.6-0.2-0.70.1-0.8-0.6-0.70.8-0.90.90.2
Delta time in closed arm before/after self-admin1.31.33.3-1.81.71.1-1.60.91.10.4-0.40.4-0.4-1.1
Delta time in open arm before/after self-admin1.01.01.5-0.80.71.0-0.81.10.91.2-1.11.2-1.2-0.8
Diff in mean of infusions in LGA sessions1.92.12.41.5-1.2-1.51.3-1.5-1.5-1.41.5-1.51.61.3
Delay discount exponential model param2.12.22.71.6-1.5-1.61.2-1.6-1.4-1.61.5-1.61.61.1
Extinction: sum of active levers before priming0.90.91.90.6-0.5-0.90.4-1.1-0.9-1.41.2-1.31.20.4
Active lever presses in extinction session 62.72.63.21.6-1.6-1.71.6-1.7-1.7-1.81.6-1.51.51.4
Bone: final force1.11.83.0-1.20.81.4-0.81.61.21.6-1.61.7-1.7-0.8
Bone: final moment0.91.42.4-1.00.61.3-0.61.41.11.4-1.41.5-1.5-0.7
Food consumed during 24 hour testing period0.70.81.1-1.11.00.9-0.80.90.90.8-1.00.8-0.8-0.7
Glucose1.52.32.6-1.61.61.6-1.51.51.51.4-1.41.4-1.5-1.6
Heart weight0.20.30.70.2-0.2-0.50.2-0.6-0.5-0.80.8-0.80.70.4
Delay discount hyperbolic model param2.93.13.61.8-1.7-1.81.5-1.9-1.7-1.91.9-1.91.91.4
Intermittent access intake day 1-15 change6.56.57.82.2-2.2-2.62.4-2.6-2.6-2.82.7-2.72.62.5
Intermittent access intake escalation5.85.78.11.7-1.8-2.31.9-2.5-2.4-2.82.7-2.72.72.2
Intermittent access intake escalation 27.27.19.92.0-2.1-2.62.1-2.8-2.7-3.13.1-3.02.92.4
Intermitt. access day 1 inactive lever presses0.10.10.4-0.30.0-0.20.0-0.3-0.2-0.60.5-0.50.50.3
Intermitt. access day 15 inactive lever presses0.50.50.80.5-0.6-0.70.5-0.7-0.7-0.80.9-0.80.80.8
Intermitt. access escalation Index0.20.20.60.1-0.20.30.30.40.30.7-0.80.6-0.6-0.2
Intermittent access day 1 total infusions0.00.00.1-0.20.20.2-0.10.20.30.2-0.20.2-0.2-0.1
Intermittent access day 15 total infusions1.92.13.01.0-1.1-1.41.2-1.5-1.4-1.71.7-1.61.61.5
Intermittent access terminal intake (last 3 days)1.01.11.70.8-1.0-1.01.0-1.1-1.0-1.31.2-1.11.11.1
Intermittent access total infusions0.20.20.40.2-0.3-0.40.3-0.5-0.3-0.60.5-0.50.50.5
Intermittent access day 1 locomotion0.40.40.60.5-0.5-0.60.5-0.7-0.5-0.70.7-0.70.80.7
Intermittent access day 15 total locomotion3.53.74.51.8-1.7-2.01.7-2.0-1.9-2.12.0-2.12.11.8
Intermittent access total locomotion0.91.11.41.0-1.0-1.11.0-1.1-1.0-1.21.0-1.01.01.0
Intermittent access standard deviation2.62.84.11.2-1.4-1.61.3-1.7-1.7-2.01.9-1.81.81.8
Left kidney weight0.10.20.70.5-0.8-0.30.6-0.2-0.4-0.10.1-0.0-0.10.4
Right kidney weight1.54.25.32.0-2.3-2.02.1-2.0-2.2-2.02.0-1.91.72.2
Cocaine induced anxiety0.70.82.11.3-1.4-0.91.2-0.8-1.0-0.70.7-0.50.40.6
Post-drug Anxiety0.70.71.81.3-1.3-0.91.0-0.7-0.9-0.40.7-0.40.50.8
Baseline Anxiety0.20.20.4-0.00.1-0.3-0.1-0.3-0.3-0.30.6-0.50.60.5
Tail length3.09.011.02.5-2.7-3.02.8-3.1-3.1-3.33.3-3.23.03.1
Length with tail2.07.48.72.7-2.9-2.72.9-2.7-2.8-2.72.6-2.52.42.9
Length without tail0.20.30.90.9-1.0-0.50.9-0.3-0.5-0.10.0-0.00.20.6
Times rat made contact with spout0.30.30.8-0.90.90.6-0.80.50.60.3-0.30.3-0.3-0.4
Lifetime Intake0.10.10.20.1-0.2-0.30.2-0.3-0.2-0.40.3-0.30.30.4
Liver weight, left2.64.25.6-2.02.32.0-2.42.02.21.9-1.81.8-1.8-2.2
Liver weight, right1.72.83.2-1.41.51.7-1.71.71.71.8-1.71.7-1.7-1.8
Locomotor activity3.55.58.12.7-2.8-2.42.8-2.2-2.5-2.22.0-1.91.82.2
Locomotor testing distance2.03.44.52.0-2.1-1.92.1-1.8-2.0-1.81.7-1.61.51.6
Locomotor testing rearing0.00.00.2-0.30.1-0.0-0.1-0.1-0.2-0.30.4-0.30.3-0.0
Locomotion in novel chamber0.20.20.50.2-0.1-0.40.1-0.5-0.4-0.70.6-0.60.5-0.2
Locomotion in novel chamber post-restriction0.80.91.20.6-0.7-1.00.9-1.0-1.0-1.11.0-1.11.11.0
Fecal boli incidents, locomotor time 11.82.02.9-1.51.21.5-1.71.41.41.2-1.21.3-1.4-1.5
Change in fecal boli incidents, locomotor task0.30.31.10.3-0.6-0.40.8-0.3-0.5-0.40.3-0.20.21.0
Time >=10cm from walls, locomotor time 10.40.51.4-0.30.00.60.00.80.50.7-0.71.0-1.2-0.6
Bouts of movement, locomotor time 10.20.20.50.2-0.3-0.40.2-0.4-0.3-0.50.5-0.50.40.7
Total resting periods, locomotor time 10.20.30.70.4-0.4-0.50.4-0.5-0.4-0.50.5-0.50.50.8
Rest time, locomotor task time 10.20.30.50.7-0.7-0.60.4-0.5-0.4-0.40.3-0.50.50.6
Distance moved, locomotor task time 10.50.51.1-0.40.40.60.00.80.60.8-0.81.0-1.1-0.6
Vertical activity count, locomotor time 10.20.21.0-1.00.60.5-0.30.50.30.2-0.20.3-0.3-0.1
Time >=10cm from walls, locomotor time 21.51.62.9-1.71.31.4-1.21.41.21.0-1.01.2-1.4-1.1
Bouts of movement, locomotor time 20.70.71.81.3-1.3-0.91.0-0.8-0.9-0.40.3-0.50.50.8
Total resting periods, locomotor time 20.60.71.71.3-1.2-0.91.0-0.7-0.8-0.30.3-0.40.50.7
Rest time, locomotor task time 20.70.81.21.1-1.1-0.91.1-0.8-0.9-0.60.7-0.60.60.8
Distance moved, locomotor task time 20.91.11.6-1.21.31.0-1.21.01.00.8-0.80.8-0.8-1.2
Vertical activity count, locomotor time 21.01.12.4-1.61.31.1-1.40.91.00.6-0.70.7-0.7-0.9
Light reinforcement 16.211.313.83.7-3.5-3.63.4-3.5-3.5-3.23.2-3.23.23.0
Light reinforcement 22.33.14.02.0-2.0-1.81.9-1.8-1.8-1.61.5-1.61.71.6
Bone: marrow area0.20.30.6-0.50.40.6-0.30.60.60.8-0.80.7-0.7-0.3
Bone: maximum diameter0.91.63.01.5-1.7-1.21.7-1.1-1.3-0.90.8-0.80.81.4
Bone: maximum force1.11.93.0-1.40.91.5-0.91.61.31.6-1.51.6-1.7-0.8
Bone: maximum moment0.91.52.4-1.20.71.3-0.81.41.21.4-1.41.5-1.5-0.7
Mean time between licks in bursts4.05.77.02.2-2.1-2.42.1-2.5-2.5-2.62.6-2.62.52.0
Mean num. licks in bursts0.00.00.1-0.0-0.10.10.00.20.10.3-0.30.2-0.20.2
Cd content in liver0.20.20.3-0.30.30.5-0.30.50.40.5-0.50.6-0.5-0.5
Co content in liver0.50.60.80.7-0.7-0.70.6-0.8-0.8-0.70.9-0.80.70.7
Cu content in liver0.10.20.40.2-0.30.20.20.40.10.6-0.50.6-0.70.0
Fe content in liver0.00.00.1-0.10.1-0.1-0.2-0.2-0.1-0.30.3-0.30.30.2
K content in liver0.10.10.40.6-0.6-0.10.40.1-0.10.4-0.30.4-0.50.0
Mg content in liver0.10.10.30.6-0.6-0.10.40.1-0.10.4-0.30.4-0.60.0
Mn content in liver1.51.73.81.9-2.0-1.21.9-1.0-1.3-0.60.5-0.40.51.5
Na content in liver0.80.91.6-0.30.30.9-0.61.00.91.1-1.31.3-1.1-0.9
Rb content in liver0.40.51.2-0.0-0.20.50.00.70.41.0-1.01.0-1.1-0.4
Se content in liver0.20.20.40.6-0.6-0.50.4-0.5-0.5-0.30.3-0.40.40.6
Sr content in liver0.10.10.3-0.40.40.1-0.4-0.10.1-0.50.2-0.30.6-0.1
Zn content in liver1.41.63.10.5-0.5-1.10.4-1.4-1.2-1.61.7-1.71.70.9
Bone: minimum diameter0.00.10.20.1-0.30.00.40.1-0.00.2-0.30.3-0.20.3
Time in familiar zone, hab. session 12.42.23.11.1-1.1-1.41.1-1.5-1.5-1.61.8-1.61.71.7
Time in novel zone, hab. session 11.00.91.8-0.60.30.9-0.41.00.91.2-1.31.3-1.3-0.8
Total zone transitions, hab. session 11.21.63.61.9-1.8-1.41.6-1.2-1.3-0.80.8-0.80.81.1
Total locomotion distance, hab. session 11.52.24.82.2-2.2-1.52.0-1.2-1.5-0.80.8-0.70.71.5
Locomotion velocity, hab. session 11.92.75.92.4-2.2-1.82.1-1.5-1.7-1.11.1-1.01.01.5
Time in familiar zone, hab. session 26.16.38.22.0-1.9-2.51.9-2.7-2.5-2.72.8-2.92.82.5
Time in novel zone, hab. session 24.44.46.0-1.71.52.1-1.42.32.02.4-2.42.5-2.4-1.9
Total zone transitions, hab. session 20.30.40.91.0-0.6-0.00.40.20.10.7-0.70.8-0.7-0.5
Total locomotion distance, hab. session 21.21.64.12.0-1.7-1.41.5-1.2-1.3-0.80.9-0.80.81.0
Locomotion velocity, hab. session 21.31.74.92.2-1.8-1.41.6-1.2-1.3-0.70.7-0.70.70.9
Novel to familiar place preference ratio4.04.15.9-1.51.42.0-1.32.11.92.3-2.42.4-2.4-2.0
Novelty place preference2.42.43.7-1.11.01.5-0.91.61.51.8-1.91.9-1.9-1.5
Time in novel zone, NPP test2.72.84.1-1.31.11.6-1.11.81.61.9-2.02.0-2.0-1.5
Total zone transitions, NPP test0.10.21.01.0-0.5-0.30.2-0.1-0.10.2-0.20.3-0.2-0.4
Total locomotion distance, NPP test0.10.20.70.8-0.6-0.20.30.0-0.00.4-0.30.4-0.4-0.1
Locomotion velocity, NPP test0.20.31.21.1-0.9-0.50.6-0.3-0.30.1-0.00.1-0.10.1
Intraocular pressure0.20.20.6-0.70.80.2-0.7-0.10.1-0.40.5-0.50.5-0.2
Delta distance traveled before/after self-admin1.92.02.31.4-1.4-1.41.4-1.4-1.5-1.41.5-1.41.41.4
Delta ambulatory time before/after self-admin2.02.22.41.6-1.5-1.51.5-1.5-1.5-1.41.4-1.41.41.5
Parametrial fat weight0.40.71.10.4-0.7-0.80.8-0.9-0.8-1.01.0-1.00.71.0
Pavlov. Cond. lever latency0.10.10.3-0.50.40.1-0.4-0.00.0-0.30.3-0.30.3-0.1
Pavlov. Cond. magazine entry latency2.93.84.51.9-1.6-2.11.7-2.1-1.9-2.02.0-2.12.11.8
Pavlov. Cond. change in total contacts0.10.10.10.4-0.2-0.30.3-0.3-0.2-0.20.2-0.20.20.2
Pavlov. Cond. index score0.50.61.11.1-0.9-0.90.9-0.8-0.8-0.50.5-0.60.60.8
Pavlov. Cond. latency score0.50.61.41.2-1.0-0.91.0-0.8-0.8-0.50.4-0.50.50.8
Pavlov. Cond. lever contacts0.20.20.70.8-0.7-0.40.7-0.2-0.30.1-0.20.2-0.10.3
Pavlov. Cond. magazine entry number0.70.91.2-1.00.81.1-0.81.10.90.9-0.91.0-1.0-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.10.1-0.2-0.1-0.3-0.2-0.50.5-0.60.60.1
Pavlov. Cond. lever-magazine prob. diff.0.81.01.61.3-1.1-1.11.1-1.1-1.0-0.80.8-0.90.91.1
Pavlov. Cond. response bias1.21.41.71.3-1.1-1.31.1-1.3-1.2-1.11.1-1.21.21.2
Pavlov. Cond. lever latency0.81.11.8-0.61.30.9-1.20.91.21.1-1.20.9-0.9-1.3
Pavlov. Cond. magazine entry latency0.50.60.90.5-0.9-0.70.9-0.7-0.8-0.70.7-0.70.61.0
Pavlov. Cond. change in total contacts0.71.01.30.6-1.0-0.91.0-0.9-1.1-1.11.1-1.01.01.1
Pavlov. Cond. index score0.91.21.60.6-1.2-0.91.2-1.0-1.2-1.11.2-1.01.01.3
Pavlov. Cond. latency score0.91.11.60.7-1.3-0.91.2-0.9-1.2-1.01.1-0.90.91.3
Pavlov. Cond. lever contacts0.71.01.50.4-1.0-0.81.0-0.9-1.1-1.11.2-1.01.01.2
Pavlov. Cond. magazine entry number0.80.91.4-0.71.10.9-1.10.91.00.9-1.00.9-0.9-1.2
Pavlov. Cond. intertrial magazine entries0.40.51.0-0.91.00.7-0.90.60.70.5-0.40.4-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.91.21.70.7-1.3-1.01.3-1.0-1.2-1.11.2-1.00.91.3
Pavlov. Cond. response bias1.82.43.20.9-1.5-1.41.5-1.5-1.7-1.71.8-1.61.61.7
Time in closed arm before self-admin0.60.71.4-0.00.10.6-0.30.80.71.1-1.21.1-1.1-0.8
Time in closed arm after self-admin0.00.00.00.00.0-0.1-0.0-0.1-0.1-0.10.1-0.20.2-0.1
Time in open arm before self-admin0.60.71.20.6-0.6-0.80.7-0.9-0.8-1.10.9-0.90.90.6
Time in open arm after self-admin0.80.91.0-1.00.91.0-0.91.00.91.0-0.90.9-0.9-0.8
Bone: periosteal estimation0.30.51.2-0.30.10.7-0.00.80.61.0-1.11.0-1.0-0.2
Bone: periosteal perimeter0.20.30.90.6-0.9-0.31.0-0.2-0.5-0.1-0.00.1-0.10.7
Bone: post-yield work0.50.71.1-1.00.91.0-0.90.90.90.9-0.80.8-0.8-0.5
Progressive ratio test 1 active lever presses0.10.10.3-0.50.50.3-0.50.20.40.1-0.20.1-0.0-0.0
Progressive ratio test 1 breakpoint0.20.20.4-0.60.60.4-0.50.40.50.3-0.30.2-0.1-0.1
Progressive ratio test 1 inactive lever presses0.00.00.10.2-0.2-0.20.1-0.2-0.1-0.10.0-0.20.20.3
Progressive ratio test 2 active lever presses0.10.10.4-0.1-0.0-0.20.0-0.3-0.2-0.60.5-0.50.50.4
Progressive ratio test 2 breakpoint0.20.20.40.2-0.3-0.40.3-0.4-0.3-0.60.5-0.50.50.6
Progressive ratio test 2 inactive lever presses0.00.00.10.2-0.3-0.20.2-0.2-0.1-0.30.2-0.10.10.2
Incentive Sensitization - Responses0.10.10.4-0.20.1-0.2-0.0-0.3-0.1-0.60.4-0.40.40.2
Incentive Sensitization - Breakpoint0.10.10.4-0.1-0.0-0.30.1-0.4-0.2-0.70.5-0.50.50.3
Sum of active levers in priming session hrs 5-60.00.00.00.10.00.0-0.10.00.1-0.0-0.00.0-0.1-0.1
Progressive ratio0.30.30.9-0.40.90.5-1.00.40.70.5-0.30.3-0.3-0.6
Food seeking constrained by brief footshock0.20.20.80.9-0.3-0.60.2-0.6-0.3-0.40.3-0.40.40.0
Seeking ratio, punishment vs. effort0.30.30.80.7-0.9-0.60.7-0.5-0.7-0.40.3-0.40.40.4
Retroperitoneal fat weight0.31.01.5-1.01.21.0-1.20.91.11.0-0.90.8-0.9-1.0
Reaction time number correct0.71.02.7-1.61.51.1-1.30.91.00.6-0.70.5-0.4-0.7
Reaction time mean minus median0.70.91.40.6-0.9-0.80.9-0.9-1.0-1.01.1-1.01.01.2
Reaction time mean minus median AUC0.10.10.40.3-0.6-0.10.60.0-0.20.2-0.10.2-0.20.5
Reaction time num false alarms0.20.21.2-1.10.70.5-0.50.40.40.1-0.20.2-0.1-0.1
Reaction time num false alarms AUC0.30.41.6-1.30.90.7-0.70.50.50.2-0.20.2-0.1-0.3
Reaction time trials correct on left0.71.02.7-1.61.51.1-1.30.91.00.6-0.70.5-0.4-0.7
Reaction time trials on left0.71.02.6-1.61.41.1-1.30.91.00.6-0.70.5-0.4-0.7
Reaction time mean0.00.10.20.1-0.40.10.30.1-0.10.2-0.00.2-0.20.4
Reaction time mean AUC0.00.10.20.0-0.40.10.30.2-0.00.3-0.10.3-0.30.3
Median of all reaction times0.20.30.6-0.30.10.5-0.10.60.40.7-0.60.8-0.7-0.2
Reaction time omissions0.30.40.70.8-0.8-0.60.7-0.6-0.6-0.50.4-0.50.50.3
Reaction time false alarm rate0.00.00.1-0.40.10.2-0.00.20.10.1-0.10.2-0.2-0.0
Reaction time premature initiation rate1.01.32.20.8-0.8-1.10.8-1.2-1.2-1.31.5-1.41.40.9
Reaction time premature initiations0.50.71.6-0.0-0.0-0.60.2-0.8-0.7-1.11.2-1.21.30.7
Std. dev. reaction times0.20.30.80.3-0.8-0.40.6-0.4-0.6-0.50.6-0.40.40.9
Reaction time trials completed0.71.02.6-1.61.41.1-1.30.91.00.6-0.70.5-0.4-0.7
Reaction time trials AUC0.71.02.8-1.71.51.1-1.40.91.00.5-0.60.4-0.3-0.7
Run reversals in cocaine runway, females0.40.40.60.8-0.5-0.70.7-0.6-0.5-0.60.5-0.50.60.8
Run reversals in cocaine runway, males1.61.52.21.5-1.0-1.31.3-1.3-1.3-1.21.0-1.21.21.3
Latency to leave start box in cocaine runway0.91.02.21.3-1.4-1.01.5-0.9-1.0-0.80.7-0.50.50.6
Latency to leave start box in cocaine runway, F0.20.20.50.6-0.6-0.10.70.20.00.1-0.40.6-0.7-0.2
Latency to leave start box in cocaine runway, M2.42.33.61.0-1.2-1.51.1-1.6-1.5-1.71.9-1.81.91.2
Std. dev. time between licks in bursts0.91.11.91.0-1.3-1.01.4-0.9-1.1-0.90.9-0.80.81.3
Total sessions with >9 infusions0.00.00.1-0.0-0.20.10.20.10.0-0.0-0.30.2-0.30.1
Short access day 1 total inactive lever presses0.10.10.20.3-0.4-0.30.2-0.3-0.2-0.30.1-0.30.30.1
Short access day 10 total inactive lever presses0.00.00.1-0.20.00.0-0.2-0.00.0-0.20.2-0.1-0.0-0.3
Short access day 1 total infusions0.30.30.90.8-1.0-0.50.7-0.4-0.5-0.30.2-0.20.20.5
Short access day 10 total infusions0.00.10.2-0.20.0-0.1-0.1-0.10.0-0.30.1-0.30.40.4
Short access total infusions0.00.00.00.0-0.2-0.00.10.00.0-0.1-0.10.1-0.10.1
Short access day 1 locomotion1.21.32.11.2-1.5-1.11.4-1.0-1.1-1.00.9-0.90.91.4
Short access day 10 total locomotion3.74.25.71.7-2.0-2.01.9-2.1-2.0-2.42.0-2.22.11.9
Short access total locomotion0.91.01.40.9-1.2-1.01.1-0.9-0.9-1.10.8-0.90.81.0
One hour access (0.3 mA shock)0.20.20.3-0.50.50.4-0.50.40.60.3-0.40.4-0.3-0.1
Compulsive drug intake1.21.31.9-0.80.81.1-0.81.21.01.2-1.31.3-1.4-1.2
One hour access (shock baseline)0.10.10.4-0.20.0-0.2-0.0-0.3-0.1-0.40.4-0.50.60.7
Social response proportion0.90.92.01.4-1.3-1.01.0-0.9-1.0-0.70.7-0.70.70.8
Social responses7.49.512.43.2-3.5-3.13.3-3.0-3.3-3.02.9-2.72.73.1
Social time0.60.81.7-0.60.90.8-1.00.81.00.9-0.70.9-1.0-1.3
Soleus weight9.226.929.3-5.25.15.4-5.05.45.45.2-5.25.2-5.1-4.8
Bone: stiffness2.84.55.9-2.11.72.2-1.72.32.12.3-2.32.3-2.4-1.6
Tibialis anterior weight1.34.44.9-2.22.22.1-2.02.12.22.1-2.22.1-2.1-1.9
Time to tail flick, vehicle, before self-admin0.60.61.21.0-1.1-0.81.0-0.7-0.8-0.50.3-0.40.40.8
Time to tail flick, vehicle, after self-admin0.20.20.4-0.20.2-0.2-0.2-0.4-0.3-0.40.6-0.60.60.1
Time to tail flick, test, before self-admin0.30.30.80.9-0.9-0.60.9-0.4-0.5-0.30.2-0.20.20.6
Time to tail flick, test, after self-admin0.30.30.60.8-0.7-0.60.6-0.6-0.7-0.30.3-0.40.50.7
Delta time to tail flick, vehicle, before/after SA0.60.61.6-1.21.30.8-1.20.60.80.4-0.10.2-0.2-0.8
Delta time to tail flick, test, before/after SA0.20.10.4-0.0-0.0-0.3-0.1-0.4-0.3-0.40.4-0.60.60.4
Tibia length0.92.63.51.5-1.5-1.61.5-1.6-1.7-1.71.9-1.61.61.6
Ambulatory time before self-admin0.40.40.7-0.50.40.7-0.50.70.70.6-0.80.8-0.8-0.7
Ambulatory time after self-admin0.30.30.50.7-0.7-0.60.7-0.6-0.6-0.60.5-0.50.40.6
Bone: tissue strength1.71.62.1-1.01.01.3-1.11.31.31.3-1.31.4-1.4-1.3
Total heroin consumption1.82.22.61.6-1.2-1.61.3-1.6-1.4-1.61.5-1.51.51.3
Bone: trabecular number0.81.32.81.6-1.7-1.11.6-0.9-1.2-0.70.5-0.60.61.2
Bone: trabecular spacing0.91.23.4-1.81.81.0-1.70.71.00.3-0.00.1-0.2-0.9
Bone: trabecular thickness0.70.82.51.4-1.4-0.31.60.1-0.40.5-0.70.8-0.80.3
Bone: trabecular tissue density1.82.63.6-1.61.91.6-1.91.51.71.4-1.31.4-1.4-1.8
Water consumed over 24 hours0.50.61.1-0.50.40.8-0.30.90.70.9-1.11.0-1.0-0.4
Number of responses in last shaping day0.10.20.40.2-0.3-0.30.4-0.3-0.3-0.60.3-0.30.40.6