Hub : Genes

LOC108351405

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XR_010053559.1 0.05 0.04 1.8e-03 0.03 0.02 0.01 0.02 2.1e-03 5.9e-03 2.5e-02 8.5e-03
2 pVTA intron excision ratio chr7_10027938_10031130 0.05 0.04 6.5e-03 0.02 0.03 0.02 0.02 1.2e-02 2.9e-03 7.3e-03 4.7e-03
3 BLA isoform ratio XR_010053559.1 0.08 0.06 5.8e-04 0.07 0.06 0.04 0.06 2.3e-04 6.6e-04 4.9e-03 5.1e-04
4 pVTA intron excision ratio chr7_10033620_10037762 0.17 0.1 4.3e-10 0.13 0.13 0.13 0.13 2.0e-10 2.6e-10 2.3e-10 2.6e-10
5 Brain gene expression LOC108351405 0.12 0.08 2.3e-10 0.09 0.09 0.1 0.1 1.6e-08 4.3e-09 1.7e-09 1.9e-09
6 PL gene expression LOC108351405 0.09 0.06 3.3e-11 0.09 0.09 0.09 0.1 4.5e-10 2.0e-10 3.8e-10 1.4e-10
7 Liver gene expression LOC108351405 0.15 0.09 0.0e+00 0.12 0.15 0.15 0.15 9.3e-14 2.4e-16 3.9e-16 3.8e-16
8 Adipose gene expression LOC108351405 0.13 0.08 2.4e-13 0.07 0.09 0.09 0.08 3.6e-08 7.2e-10 3.5e-10 1.4e-09
9 IL gene expression LOC108351405 0.17 0.13 6.6e-03 0.07 0.06 0.06 0.05 1.1e-02 1.9e-02 1.8e-02 2.6e-02
10 pVTA gene expression LOC108351405 0.11 0.07 1.2e-10 0.12 0.12 0.12 0.12 2.8e-10 1.4e-09 6.0e-10 6.7e-10
11 Liver mRNA stability LOC108351405 0.09 0.06 3.3e-10 0.09 0.07 0.07 0.08 5.5e-10 1.6e-08 8.1e-08 4.9e-09
12 LHb gene expression LOC108351405 0.12 0.09 5.4e-03 0.08 0.09 0.08 0.08 6.1e-03 4.0e-03 6.6e-03 6.4e-03
13 PL isoform ratio XR_010053557.1 0.02 0.02 1.0e-02 0.02 0.01 0.01 0.01 5.5e-03 8.1e-03 2.0e-02 8.2e-03
14 BLA gene expression LOC108351405 0.08 0.05 3.0e-05 0.07 0.09 0.09 0.09 1.5e-04 1.6e-05 2.7e-05 1.1e-05
15 IC gene expression LOC108351405 0.1 0.07 7.7e-04 0.03 0.03 0.04 0.03 3.1e-02 2.1e-02 1.0e-02 2.6e-02
16 NAcc gene expression LOC108351405 0.1 0.06 0.0e+00 0.13 0.13 0.13 0.13 2.4e-19 1.2e-18 1.5e-18 5.1e-19
17 Brain mRNA stability LOC108351405 0.04 0.03 1.4e-03 0.02 0.02 0.02 0.02 4.0e-03 3.0e-03 9.2e-03 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.30.52.4-0.8-1.5-0.80.8-0.0-0.80.20.10.70.70.70.4-0.90.10.80.71.0
Area under the delay curve2.02.32.81.61.21.4-1.41.61.41.71.41.71.71.71.71.31.51.51.41.5
BMI with tail6.723.026.35.04.05.1-5.15.15.14.94.94.64.64.64.85.14.94.54.74.4
BMI without tail2.26.68.12.82.62.8-2.82.72.82.62.72.32.32.32.52.82.62.22.42.1
Body weight1.04.24.82.11.72.1-2.12.22.22.12.12.02.02.02.12.22.02.12.11.9
Weight adjusted by age0.40.61.60.81.30.8-0.80.80.80.70.90.30.30.30.70.80.71.00.70.3
Bone surface0.91.77.6-1.9-2.8-1.91.9-0.9-1.9-0.6-0.70.30.30.3-0.3-2.0-0.60.00.30.7
Bone volume0.91.67.0-1.9-2.6-1.91.9-0.8-1.8-0.4-0.60.30.30.3-0.1-2.0-0.50.30.30.8
Breakpoint value in progressive ratio session3.54.27.2-1.7-1.3-1.71.7-2.0-1.7-2.1-2.4-2.2-2.2-2.2-2.2-1.8-2.1-2.7-2.2-2.2
Number of licking bursts0.20.31.40.81.20.7-0.70.40.70.20.2-0.2-0.2-0.20.10.60.20.2-0.3-0.3
Context. condit. distance diff. score0.30.40.50.70.70.6-0.60.50.60.60.70.60.60.60.60.70.70.30.70.5
Locomotion velocity, session 10.80.92.5-1.4-1.6-1.31.3-0.9-1.2-0.8-0.7-0.4-0.4-0.4-0.7-1.1-0.8-0.5-0.4-0.2
Locomotion distance, session 10.60.74.9-1.2-2.2-1.11.1-0.7-1.1-0.5-0.40.10.10.1-0.3-0.9-0.50.00.10.5
Locomotion velocity, session 24.65.411.0-2.9-3.3-2.82.8-2.5-2.7-2.3-2.2-1.5-1.5-1.5-2.1-2.6-2.3-2.1-1.7-1.3
Locomotion distance, session 22.23.19.9-2.3-3.1-2.22.2-1.7-2.2-1.7-1.6-1.0-1.0-1.0-1.5-2.1-1.7-0.9-1.1-0.6
Locomotion velocity, session 36.06.89.2-2.4-1.8-2.42.4-2.8-2.4-2.8-2.8-2.6-2.6-2.6-2.8-2.5-2.7-3.0-2.7-2.7
Locomotion distance, session 30.00.00.10.10.40.1-0.10.00.10.00.0-0.0-0.0-0.0-0.00.10.1-0.2-0.0-0.2
Stereotopy head waving bouts, day 35.26.17.1-2.5-2.6-2.52.5-2.6-2.5-2.6-2.7-2.2-2.2-2.2-2.5-2.5-2.6-2.6-2.5-2.1
Stereotopy head waving duration, day 36.37.68.9-2.8-2.5-2.82.8-2.9-2.8-2.9-3.0-2.5-2.5-2.5-2.8-2.7-2.9-3.0-2.9-2.5
Locomotion velocity, session 70.50.61.0-1.0-0.2-1.01.0-1.0-1.0-0.6-0.5-0.8-0.8-0.8-0.6-1.0-0.6-0.6-0.5-0.8
Locomotion distance, session 70.30.41.80.71.30.8-0.80.50.70.60.60.10.10.10.50.70.50.40.30.1
Stereotopy head waving bouts, day 70.10.20.9-0.4-1.0-0.50.5-0.1-0.4-0.1-0.10.40.40.40.1-0.4-0.1-0.10.00.4
Stereotopy head waving duration, day 70.60.72.4-1.1-1.6-1.11.1-0.7-1.1-0.7-0.7-0.2-0.2-0.2-0.5-1.1-0.7-0.5-0.5-0.1
Locomotion velocity, session 81.01.24.4-1.5-2.1-1.51.5-1.1-1.5-0.9-0.8-0.3-0.3-0.3-0.7-1.4-0.9-0.6-0.4-0.1
Locomotion distance, session 80.20.31.3-0.7-1.1-0.70.7-0.6-0.7-0.5-0.4-0.2-0.2-0.2-0.4-0.6-0.5-0.5-0.2-0.1
Degree of sensitization distance0.50.50.70.60.50.6-0.60.60.60.80.80.70.70.70.80.60.70.80.80.7
Degree of sensitization stereotypy1.41.62.50.90.40.9-0.91.30.91.31.31.61.61.61.40.91.31.31.41.5
Conditioned locomotion1.61.94.01.72.01.7-1.71.51.71.31.30.90.90.91.21.71.31.10.80.7
Cocaine response after cond. corrected5.87.011.53.13.43.0-3.02.73.02.72.62.12.12.12.53.02.62.22.11.8
Cocaine response after cond. not corrected6.27.312.23.23.53.2-3.22.83.12.82.72.22.22.22.63.02.72.22.11.8
Cocaine response before conditioning0.60.71.0-1.0-0.8-0.90.9-0.9-0.9-0.8-0.9-0.7-0.7-0.7-0.8-1.0-0.8-1.0-0.7-0.7
Saline control response0.20.20.60.70.70.7-0.70.60.70.40.20.20.20.20.40.70.4-0.10.20.2
Bone: connectivity density0.30.51.3-0.2-0.9-0.20.20.4-0.20.50.51.01.01.00.7-0.20.50.90.91.1
Bone: cortical apparent density0.81.11.30.90.70.9-0.91.20.91.11.01.11.11.11.10.91.11.01.11.1
Bone: cortical area0.30.51.2-0.0-0.2-0.00.00.5-0.00.80.71.01.01.00.9-0.10.71.01.01.1
Bone: cortical porosity0.30.30.8-0.8-0.9-0.80.8-0.4-0.8-0.4-0.3-0.2-0.2-0.2-0.3-0.8-0.40.1-0.2-0.0
Bone: cortical porosity0.20.31.3-0.7-1.1-0.70.7-0.2-0.7-0.1-0.00.20.20.20.0-0.7-0.10.30.20.4
Bone: cortical thickness0.91.42.40.80.40.8-0.81.20.81.31.21.51.51.51.40.71.21.51.51.6
Bone: cortical thickness0.10.10.90.31.00.3-0.30.00.20.0-0.0-0.4-0.4-0.4-0.10.2-0.0-0.1-0.3-0.5
Bone: cortical tissue density0.50.70.90.70.60.7-0.71.00.70.90.80.90.90.90.90.70.90.80.90.9
Condit. Reinf. active minus inactive responses4.44.97.2-2.2-1.8-2.12.1-2.4-2.1-2.3-2.3-2.1-2.1-2.1-2.3-2.1-2.2-2.7-2.3-2.2
Condit. Reinf. active-inactive response ratio2.02.24.0-1.2-0.5-1.21.2-1.6-1.2-1.5-1.5-1.6-1.6-1.6-1.6-1.2-1.5-2.0-1.6-1.8
Condit. Reinf. active responses4.15.16.5-2.5-2.6-2.52.5-2.4-2.5-2.3-2.3-1.9-1.9-1.9-2.2-2.3-2.3-2.2-2.1-1.8
Condit. Reinf. inactive responses1.11.44.6-1.6-2.1-1.61.6-1.2-1.5-1.1-1.0-0.6-0.6-0.6-0.9-1.4-1.1-0.5-0.5-0.3
Incentive salience index mean2.53.14.2-1.9-2.1-1.91.9-2.0-1.9-1.9-1.8-1.4-1.4-1.4-1.8-1.9-1.7-1.9-1.5-1.4
Condit. Reinf. lever presses0.30.43.4-0.8-1.8-0.80.8-0.4-0.7-0.3-0.20.30.30.3-0.1-0.8-0.30.20.30.6
Condit. Reinf. active minus inactive responses1.92.53.9-1.2-0.3-1.21.2-1.4-1.2-1.6-1.7-1.9-1.9-1.9-1.7-1.3-1.7-1.5-1.9-2.0
Condit. Reinf. active-inactive response ratio0.20.20.90.40.90.5-0.50.20.4-0.2-0.1-0.6-0.6-0.6-0.30.5-0.30.1-0.7-0.7
Condit. Reinf. active responses2.12.93.6-1.6-0.7-1.61.6-1.6-1.6-1.7-1.9-1.9-1.9-1.9-1.7-1.7-1.8-1.7-1.9-1.9
Condit. Reinf. inactive responses1.31.62.3-1.4-0.7-1.41.4-1.4-1.4-1.1-1.5-1.2-1.2-1.2-1.2-1.5-1.2-1.5-1.1-1.2
Condit. Reinf. lever presses1.72.33.4-1.2-0.4-1.21.2-1.5-1.3-1.5-1.7-1.8-1.8-1.8-1.6-1.3-1.6-1.8-1.8-1.8
Condit. Reinf. lever reinforcers received1.52.13.1-1.2-0.2-1.21.2-1.3-1.2-1.4-1.6-1.7-1.7-1.7-1.5-1.3-1.5-1.4-1.7-1.7
Conditioned reinforcement - actives0.71.22.5-0.80.0-0.70.7-1.1-0.8-1.1-0.7-1.6-1.6-1.6-1.2-0.8-0.9-0.5-1.3-1.5
Conditioned reinforcement - inactives0.10.10.40.40.60.4-0.40.20.40.20.4-0.1-0.1-0.10.10.50.40.40.0-0.1
Conditioned locomotion7.29.310.8-3.1-2.4-3.03.0-3.2-3.1-3.2-3.1-3.3-3.3-3.3-3.1-3.0-3.0-2.7-3.1-2.9
Patch foraging indifference point 0 sec0.10.20.40.40.00.3-0.30.60.30.50.50.60.60.60.60.20.50.60.60.7
Patch foraging indifference point AUC0.71.01.5-0.9-0.5-0.90.9-1.0-0.8-1.1-1.0-1.2-1.2-1.2-1.1-0.8-1.1-0.7-1.1-1.1
Delay disc. indifference point, 0s delay7.07.611.92.10.62.1-2.12.82.22.82.93.33.33.33.02.02.83.33.23.5
Delay disc. indifference point, 16s delay0.10.10.30.40.30.3-0.30.40.20.40.20.50.50.50.40.30.30.10.40.4
Delay disc. indifference point, 2s delay5.66.28.02.21.32.2-2.22.62.22.72.52.82.82.82.72.12.72.42.72.8
Delay disc. indifference point, 24s delay0.60.71.10.91.00.8-0.80.90.70.90.90.70.70.70.90.80.81.00.80.6
Delay disc. indifference point, 4s delay1.11.22.01.10.50.9-0.91.00.81.21.01.41.41.41.20.71.10.81.11.2
Delay disc. indifference point, 8s delay1.31.52.31.41.51.3-1.31.21.31.31.21.11.11.11.31.21.11.50.91.0
Indifference point function ln k0.10.20.50.60.70.5-0.50.50.40.50.50.40.40.40.50.30.60.20.40.3
Indifference point function log k0.10.20.50.60.70.5-0.50.50.40.50.50.40.40.40.50.30.60.20.40.3
Patch foraging total patch changes 0 sec0.10.20.30.40.10.3-0.30.50.30.40.40.50.50.50.50.20.40.50.50.5
Patch foraging total patch changes 12 sec0.60.71.41.00.91.1-1.10.91.10.80.80.50.50.50.71.20.71.00.60.5
Patch foraging total patch changes 18 sec0.81.21.4-1.2-1.0-1.11.1-1.1-1.1-1.1-1.2-1.0-1.0-1.0-1.1-1.1-1.2-1.2-1.0-1.0
Patch foraging total patch changes 24 sec0.10.10.2-0.3-0.5-0.30.3-0.2-0.3-0.3-0.5-0.2-0.2-0.2-0.3-0.3-0.4-0.4-0.2-0.2
Patch foraging total patch changes 6 sec0.20.30.6-0.7-0.8-0.70.7-0.5-0.7-0.5-0.5-0.4-0.4-0.4-0.5-0.7-0.70.1-0.4-0.3
Patch foraging time to switch 0 sec0.81.63.70.6-0.70.6-0.61.10.71.11.21.81.81.81.30.81.21.41.71.9
Patch foraging water rate 0 sec0.20.43.20.71.80.7-0.70.20.70.20.3-0.5-0.5-0.5-0.00.60.2-0.0-0.4-0.7
Patch foraging water rate 12 sec1.12.26.52.02.52.0-2.01.51.91.41.30.80.80.81.21.81.40.90.80.5
Patch foraging water rate 18 sec0.71.16.11.32.51.2-1.20.31.10.0-0.1-0.9-0.9-0.9-0.31.00.0-0.5-0.9-1.2
Patch foraging water rate 24 sec1.31.88.21.92.91.9-1.91.11.80.90.9-0.0-0.0-0.00.61.80.90.60.0-0.3
Patch foraging water rate 6 sec0.40.61.80.21.30.2-0.2-0.30.2-0.4-0.5-1.1-1.1-1.1-0.60.2-0.5-0.7-1.1-1.2
Seeking ratio, delayed vs. immediate footshock4.35.26.9-2.4-2.0-2.42.4-2.3-2.4-2.3-2.6-2.1-2.1-2.1-2.2-2.4-2.2-2.6-2.1-2.0
Distance traveled before self-admin0.10.10.30.1-0.00.1-0.10.30.20.40.40.40.40.40.50.10.50.50.60.6
Distance traveled after self-admin0.00.00.0-0.2-0.2-0.10.1-0.1-0.1-0.1-0.2-0.2-0.2-0.2-0.1-0.2-0.1-0.10.0-0.0
Extensor digitorum longus weight4.617.921.14.64.34.6-4.64.34.64.44.33.93.93.94.24.64.33.93.93.6
Bone: elastic displacement0.20.20.3-0.5-0.3-0.50.5-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.5-0.0-0.4-0.4
Bone: elastic work0.20.30.50.20.40.1-0.10.40.10.70.60.70.70.70.70.10.60.70.70.6
Bone: endosteal estimation0.10.30.50.30.30.3-0.30.30.30.60.60.70.70.70.60.30.60.40.70.6
Bone: endosteal perimeter0.40.81.4-1.1-1.1-1.21.2-1.0-1.2-0.8-0.7-0.5-0.5-0.5-0.7-1.2-0.7-0.7-0.6-0.5
Epididymis fat weight0.10.31.20.71.10.8-0.80.20.80.10.0-0.3-0.3-0.3-0.00.80.1-0.3-0.3-0.4
Delta time in closed arm before/after self-admin1.51.45.51.62.41.7-1.71.11.60.90.90.10.10.10.71.60.90.70.3-0.0
Delta time in open arm before/after self-admin0.50.50.80.60.50.6-0.60.70.60.80.70.90.90.90.80.70.70.60.70.8
Diff in mean of infusions in LGA sessions1.72.14.4-1.3-1.2-1.31.3-1.5-1.3-1.5-1.7-1.2-1.2-1.2-1.5-1.4-1.5-2.1-1.5-1.3
Delay discount exponential model param1.71.92.3-1.4-1.2-1.31.3-1.4-1.3-1.5-1.3-1.5-1.5-1.5-1.5-1.2-1.3-1.3-1.3-1.3
Extinction: sum of active levers before priming0.80.81.8-0.4-0.2-0.50.5-0.8-0.5-0.9-1.1-1.3-1.3-1.3-1.0-0.5-0.9-1.0-1.0-1.1
Active lever presses in extinction session 62.42.42.9-1.6-1.5-1.61.6-1.6-1.7-1.5-1.5-1.6-1.6-1.6-1.5-1.7-1.6-1.1-1.3-1.3
Bone: final force1.01.62.80.70.50.7-0.71.10.71.51.31.61.61.61.60.61.41.61.61.7
Bone: final moment0.81.32.30.60.40.6-0.61.00.61.31.21.51.51.51.40.51.21.51.41.5
Food consumed during 24 hour testing period0.50.71.01.01.00.9-0.90.90.90.90.80.80.80.80.90.80.90.70.70.7
Glucose2.74.25.12.01.92.1-2.12.32.12.22.22.02.02.02.12.12.12.12.01.9
Heart weight0.50.81.9-0.10.5-0.20.2-0.7-0.2-0.8-0.9-1.2-1.2-1.2-0.9-0.2-0.8-1.4-1.2-1.3
Delay discount hyperbolic model param2.93.23.9-1.8-1.4-1.61.6-1.9-1.6-2.0-1.8-2.0-2.0-2.0-2.0-1.5-1.8-1.8-1.8-1.9
Intermittent access intake day 1-15 change2.95.98.4-2.0-1.1-2.12.1-2.5-2.1-2.5-2.4-2.9-2.9-2.9-2.6-2.1-2.6-2.3-2.6-2.8
Intermittent access intake escalation2.55.27.3-1.9-1.0-1.91.9-2.3-2.0-2.4-2.3-2.7-2.7-2.7-2.5-2.0-2.4-2.2-2.4-2.6
Intermittent access intake escalation 24.24.86.1-2.0-1.1-2.02.0-2.3-2.0-2.3-2.2-2.5-2.5-2.5-2.3-2.0-2.4-2.2-2.2-2.4
Intermitt. access day 1 inactive lever presses0.10.31.30.41.10.5-0.5-0.10.4-0.2-0.0-0.8-0.8-0.8-0.30.4-0.1-0.2-0.4-0.8
Intermitt. access day 15 inactive lever presses0.20.40.6-0.8-0.6-0.70.7-0.7-0.7-0.7-0.6-0.6-0.6-0.6-0.7-0.7-0.6-0.5-0.7-0.6
Intermitt. access escalation Index0.60.81.80.3-0.20.4-0.40.70.40.91.01.21.21.21.00.30.91.31.41.3
Intermittent access day 1 total infusions0.10.20.40.10.50.2-0.2-0.30.1-0.3-0.1-0.6-0.6-0.6-0.40.0-0.1-0.3-0.6-0.6
Intermittent access day 15 total infusions2.13.25.0-1.4-0.7-1.41.4-1.8-1.5-1.9-1.7-2.2-2.2-2.2-1.9-1.6-1.7-1.7-2.0-2.1
Intermittent access terminal intake (last 3 days)1.62.13.5-1.2-0.6-1.21.2-1.5-1.3-1.5-1.3-1.9-1.9-1.9-1.5-1.3-1.3-1.2-1.6-1.7
Intermittent access total infusions0.80.91.8-0.6-0.2-0.70.7-1.0-0.7-1.0-0.7-1.4-1.4-1.4-1.1-0.8-0.8-0.7-1.1-1.2
Intermittent access day 1 locomotion1.21.52.9-0.70.0-0.60.6-1.2-0.7-1.3-1.2-1.7-1.7-1.7-1.4-0.6-1.1-1.5-1.7-1.7
Intermittent access day 15 total locomotion2.54.67.0-1.8-1.0-1.71.7-2.2-1.8-2.3-2.1-2.6-2.6-2.6-2.4-1.7-2.2-1.9-2.4-2.6
Intermittent access total locomotion2.02.44.0-1.2-0.5-1.11.1-1.6-1.2-1.6-1.5-2.0-2.0-2.0-1.7-1.2-1.5-1.5-1.8-1.9
Intermittent access standard deviation3.57.48.8-2.8-1.8-2.82.8-2.9-2.8-2.8-2.6-3.0-3.0-3.0-2.8-2.7-2.7-2.3-2.7-2.8
Left kidney weight0.00.21.40.51.20.5-0.50.10.50.20.2-0.2-0.2-0.20.10.60.3-0.1-0.0-0.3
Right kidney weight0.41.73.3-1.00.3-0.90.9-1.4-0.9-1.2-1.3-1.7-1.7-1.7-1.4-0.8-1.3-1.5-1.6-1.8
Cocaine induced anxiety1.52.14.5-1.9-2.1-1.91.9-1.4-1.8-1.4-1.4-0.9-0.9-0.9-1.2-1.7-1.3-1.1-0.9-0.7
Post-drug Anxiety1.92.04.8-1.8-2.2-1.81.8-1.4-1.6-1.3-1.6-0.7-0.7-0.7-1.2-1.5-1.4-1.6-0.9-0.6
Baseline Anxiety0.10.10.6-0.20.0-0.10.1-0.3-0.2-0.2-0.4-0.3-0.3-0.3-0.3-0.2-0.3-0.7-0.3-0.4
Tail length3.312.915.0-3.5-2.2-3.53.5-3.9-3.6-3.6-3.6-3.8-3.8-3.8-3.7-3.5-3.6-3.6-3.7-3.7
Length with tail1.98.19.6-2.7-1.8-2.82.8-3.1-2.8-2.9-2.9-3.0-3.0-3.0-2.9-2.7-2.9-2.8-2.9-2.9
Length without tail0.00.00.10.10.30.1-0.10.10.10.20.10.10.10.10.10.20.10.20.10.1
Times rat made contact with spout0.30.31.20.81.10.7-0.70.60.70.50.40.20.20.20.40.70.50.40.20.1
Lifetime Intake0.40.51.2-0.4-0.0-0.40.4-0.7-0.4-0.7-0.4-1.1-1.1-1.1-0.8-0.5-0.5-0.4-0.9-0.9
Liver weight, left1.01.72.31.51.21.5-1.51.41.51.31.21.21.21.21.21.41.31.01.11.1
Liver weight, right0.61.12.21.11.51.1-1.11.01.21.11.10.80.80.81.01.21.20.81.00.7
Locomotor activity3.55.58.3-2.7-2.7-2.82.8-2.4-2.7-2.2-2.5-2.1-2.1-2.1-2.1-2.9-2.4-1.7-1.9-1.6
Locomotor testing distance2.03.65.3-2.2-2.2-2.22.2-1.9-2.2-1.8-2.1-1.6-1.6-1.6-1.7-2.3-2.0-1.6-1.5-1.3
Locomotor testing rearing0.00.10.30.10.50.0-0.0-0.00.0-0.1-0.3-0.4-0.4-0.4-0.2-0.1-0.2-0.3-0.4-0.4
Locomotion in novel chamber0.81.11.8-0.8-0.4-0.80.8-0.9-0.8-1.1-1.2-1.3-1.3-1.3-1.1-0.8-1.2-0.7-1.2-1.2
Locomotion in novel chamber post-restriction1.21.94.3-1.1-0.5-1.11.1-1.4-1.2-1.3-1.6-1.5-1.5-1.5-1.4-1.4-1.3-2.1-1.5-1.5
Fecal boli incidents, locomotor time 11.31.92.91.11.11.3-1.31.41.51.41.41.31.31.31.41.61.31.71.71.4
Change in fecal boli incidents, locomotor task0.30.31.4-0.7-0.6-0.70.7-0.6-0.8-0.4-0.3-0.4-0.4-0.4-0.4-1.2-0.4-0.2-0.2-0.3
Time >=10cm from walls, locomotor time 10.50.52.7-0.1-0.4-0.10.10.5-0.10.60.80.60.60.60.70.00.61.71.11.1
Bouts of movement, locomotor time 10.30.30.5-0.5-0.1-0.50.5-0.7-0.5-0.6-0.4-0.7-0.7-0.7-0.6-0.5-0.5-0.4-0.6-0.7
Total resting periods, locomotor time 10.40.40.7-0.6-0.3-0.70.7-0.8-0.7-0.7-0.5-0.7-0.7-0.7-0.7-0.7-0.6-0.6-0.6-0.7
Rest time, locomotor task time 10.30.30.6-0.7-0.7-0.70.7-0.8-0.6-0.6-0.5-0.4-0.4-0.4-0.5-0.7-0.4-0.6-0.3-0.4
Distance moved, locomotor task time 10.50.82.10.5-0.20.3-0.30.80.30.91.01.01.01.01.00.20.81.51.21.2
Vertical activity count, locomotor time 10.10.31.00.71.00.6-0.60.70.50.60.60.30.30.30.60.40.50.80.40.3
Time >=10cm from walls, locomotor time 21.11.62.81.31.51.2-1.21.31.31.41.30.90.90.91.31.31.21.71.21.1
Bouts of movement, locomotor time 20.40.62.0-1.2-1.4-1.21.2-0.8-1.0-0.7-0.6-0.3-0.3-0.3-0.6-0.8-0.7-0.3-0.6-0.2
Total resting periods, locomotor time 20.30.62.1-1.1-1.4-1.11.1-0.8-1.0-0.7-0.5-0.3-0.3-0.3-0.6-0.8-0.7-0.2-0.6-0.1
Rest time, locomotor task time 20.70.91.5-1.2-1.2-1.21.2-1.1-1.2-0.9-0.9-0.7-0.7-0.7-0.9-1.0-0.9-0.8-0.8-0.6
Distance moved, locomotor task time 20.80.91.31.21.01.1-1.11.01.10.91.00.70.70.70.91.10.91.10.70.7
Vertical activity count, locomotor time 20.71.02.31.21.51.3-1.31.01.30.91.00.50.50.50.81.10.90.90.60.4
Light reinforcement 14.511.012.7-3.6-3.4-3.53.5-3.5-3.5-3.5-3.5-2.9-2.9-2.9-3.4-3.4-3.4-3.5-3.0-2.8
Light reinforcement 21.93.03.7-1.9-1.9-1.91.9-1.7-1.9-1.8-1.8-1.5-1.5-1.5-1.7-1.8-1.7-1.7-1.5-1.4
Bone: marrow area0.10.30.50.30.30.3-0.30.40.30.60.60.70.70.70.60.30.60.40.70.6
Bone: maximum diameter1.12.13.5-1.9-1.8-1.91.9-1.5-1.8-1.3-1.4-1.0-1.0-1.0-1.2-1.9-1.3-1.1-1.0-0.8
Bone: maximum force1.01.82.70.90.80.8-0.81.20.91.61.41.61.61.61.60.81.51.61.61.6
Bone: maximum moment0.91.52.30.80.80.8-0.81.10.81.41.31.51.51.51.50.71.31.41.41.5
Mean time between licks in bursts2.45.96.8-2.2-1.7-2.32.3-2.4-2.3-2.6-2.5-2.6-2.6-2.6-2.6-2.3-2.6-2.3-2.6-2.5
Mean num. licks in bursts0.00.00.2-0.2-0.2-0.10.10.0-0.10.20.10.30.30.30.2-0.00.2-0.00.40.3
Cd content in liver0.20.20.4-0.6-0.6-0.60.6-0.4-0.5-0.5-0.6-0.4-0.4-0.4-0.4-0.5-0.5-0.3-0.4-0.3
Co content in liver1.51.72.3-1.2-0.7-1.21.2-1.3-1.2-1.4-1.4-1.5-1.5-1.5-1.4-1.2-1.5-1.2-1.5-1.5
Cu content in liver0.40.51.5-1.0-1.2-1.01.0-0.6-0.9-0.5-0.4-0.2-0.2-0.2-0.4-0.9-0.5-0.0-0.2-0.0
Fe content in liver0.10.10.2-0.1-0.0-0.10.1-0.3-0.1-0.4-0.3-0.5-0.5-0.5-0.4-0.1-0.4-0.3-0.5-0.5
K content in liver0.20.20.9-0.6-1.0-0.50.5-0.2-0.5-0.2-0.20.10.10.1-0.1-0.5-0.20.10.10.3
Mg content in liver0.40.40.7-0.8-0.8-0.80.8-0.6-0.7-0.6-0.6-0.5-0.5-0.5-0.5-0.7-0.6-0.3-0.5-0.3
Mn content in liver2.22.55.6-2.2-2.4-2.22.2-1.6-2.1-1.4-1.3-0.8-0.8-0.8-1.2-2.2-1.3-0.8-0.8-0.6
Na content in liver0.80.81.90.4-0.40.5-0.50.80.50.90.91.21.21.21.00.50.81.31.21.4
Rb content in liver0.30.31.4-0.9-1.2-0.80.8-0.3-0.7-0.2-0.20.20.20.2-0.1-0.7-0.2-0.10.20.4
Se content in liver0.20.20.3-0.4-0.3-0.30.3-0.5-0.4-0.5-0.4-0.5-0.5-0.5-0.5-0.4-0.5-0.3-0.5-0.5
Sr content in liver0.00.00.20.30.50.3-0.30.20.30.10.1-0.0-0.0-0.00.10.30.1-0.0-0.0-0.1
Zn content in liver3.33.66.6-1.2-0.1-1.21.2-1.7-1.2-2.0-2.0-2.4-2.4-2.4-2.2-1.1-2.0-2.1-2.4-2.6
Bone: minimum diameter0.00.10.2-0.3-0.4-0.40.4-0.2-0.40.10.00.30.30.30.2-0.40.10.10.30.3
Time in familiar zone, hab. session 12.22.13.3-1.2-0.5-1.21.2-1.6-1.2-1.5-1.6-1.5-1.5-1.5-1.5-1.2-1.5-1.8-1.7-1.7
Time in novel zone, hab. session 11.01.01.90.4-0.00.5-0.50.90.51.01.21.21.21.21.10.41.11.41.31.3
Total zone transitions, hab. session 11.21.75.3-1.7-2.3-1.61.6-1.3-1.6-1.2-1.2-0.7-0.7-0.7-1.1-1.5-1.2-0.8-0.9-0.4
Total locomotion distance, hab. session 11.82.58.0-2.2-2.8-2.22.2-1.6-2.1-1.4-1.3-0.7-0.7-0.7-1.2-2.0-1.4-0.8-0.9-0.4
Locomotion velocity, hab. session 12.23.18.5-2.3-2.9-2.22.2-1.8-2.1-1.7-1.6-1.0-1.0-1.0-1.5-2.1-1.7-1.1-1.2-0.7
Time in familiar zone, hab. session 25.96.29.8-2.0-1.0-2.02.0-2.6-2.0-2.6-2.6-2.8-2.8-2.8-2.7-2.0-2.6-3.1-2.8-3.0
Time in novel zone, hab. session 24.34.46.81.60.91.6-1.62.11.62.32.22.42.42.42.41.62.22.62.42.5
Total zone transitions, hab. session 20.50.63.8-0.6-1.9-0.50.50.2-0.40.20.30.90.90.90.4-0.30.20.90.71.3
Total locomotion distance, hab. session 21.51.96.1-1.8-2.5-1.71.7-1.4-1.6-1.4-1.3-0.7-0.7-0.7-1.2-1.5-1.4-0.9-1.0-0.5
Locomotion velocity, hab. session 21.52.18.0-1.9-2.8-1.81.8-1.4-1.7-1.4-1.3-0.6-0.6-0.6-1.1-1.6-1.4-0.8-0.9-0.3
Novel to familiar place preference ratio3.74.16.41.40.51.4-1.42.01.52.12.32.42.42.42.21.42.22.52.52.5
Novelty place preference2.22.44.11.00.21.0-1.01.51.01.61.81.91.91.91.71.01.71.92.02.0
Time in novel zone, NPP test2.62.84.51.10.41.2-1.21.61.21.71.92.02.02.01.91.11.82.02.12.1
Total zone transitions, NPP test0.20.32.6-0.6-1.6-0.50.5-0.0-0.4-0.2-0.10.40.40.40.0-0.2-0.20.40.20.7
Total locomotion distance, NPP test0.20.32.3-0.7-1.5-0.60.6-0.2-0.5-0.1-0.10.50.50.50.1-0.4-0.10.30.20.7
Locomotion velocity, NPP test0.30.43.1-1.0-1.7-0.80.8-0.4-0.7-0.4-0.40.20.20.2-0.2-0.6-0.40.1-0.10.4
Intraocular pressure0.30.42.30.91.50.9-0.90.30.90.1-0.0-0.4-0.4-0.4-0.00.90.1-0.3-0.3-0.6
Delta distance traveled before/after self-admin0.40.40.9-0.5-0.3-0.50.5-0.6-0.5-0.7-0.8-0.7-0.7-0.7-0.7-0.5-0.8-1.0-0.7-0.7
Delta ambulatory time before/after self-admin0.30.40.7-0.6-0.5-0.60.6-0.7-0.6-0.7-0.7-0.6-0.6-0.6-0.7-0.6-0.7-0.8-0.6-0.6
Parametrial fat weight0.00.00.2-0.1-0.5-0.10.1-0.1-0.1-0.00.00.00.00.00.0-0.20.10.10.20.2
Pavlov. Cond. lever latency0.20.21.80.51.30.5-0.50.30.50.20.2-0.3-0.3-0.30.00.60.2-0.1-0.1-0.5
Pavlov. Cond. magazine entry latency3.03.95.7-1.7-1.7-1.71.7-2.1-1.8-2.1-2.1-2.0-2.0-2.0-2.1-1.8-2.1-2.4-2.1-2.0
Pavlov. Cond. change in total contacts0.10.10.2-0.2-0.4-0.20.2-0.3-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.1
Pavlov. Cond. index score0.50.61.6-0.8-1.3-0.80.8-0.9-0.8-0.8-0.8-0.5-0.5-0.5-0.8-0.9-0.8-0.9-0.7-0.5
Pavlov. Cond. latency score0.60.72.4-0.9-1.5-1.01.0-1.0-0.9-0.8-0.8-0.4-0.4-0.4-0.7-1.0-0.8-0.8-0.6-0.3
Pavlov. Cond. lever contacts0.10.21.4-0.4-1.2-0.40.4-0.2-0.4-0.1-0.10.30.30.30.0-0.5-0.10.10.10.5
Pavlov. Cond. magazine entry number0.81.02.00.80.80.8-0.81.10.81.11.11.01.01.01.10.81.11.41.11.0
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.00.60.0-0.0-0.2-0.0-0.3-0.4-0.6-0.6-0.6-0.40.1-0.4-0.4-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.6-0.9-1.3-0.90.9-1.0-0.9-1.0-0.9-0.6-0.6-0.6-0.9-1.0-0.9-1.0-0.8-0.6
Pavlov. Cond. response bias0.81.01.7-0.9-0.9-0.80.8-1.1-0.8-1.1-1.1-1.0-1.0-1.0-1.1-0.9-1.1-1.3-1.1-1.0
Pavlov. Cond. lever latency0.81.01.31.10.31.1-1.11.01.10.91.01.11.11.10.91.21.01.01.01.1
Pavlov. Cond. magazine entry latency0.40.50.7-0.8-0.3-0.80.8-0.8-0.8-0.7-0.6-0.7-0.7-0.7-0.7-0.8-0.6-0.7-0.6-0.7
Pavlov. Cond. change in total contacts0.50.71.1-0.8-0.1-0.80.8-0.8-0.8-0.8-0.9-1.0-1.0-1.0-0.8-0.9-0.9-0.7-1.0-1.0
Pavlov. Cond. index score0.60.81.1-0.9-0.2-0.90.9-0.9-1.0-0.8-0.9-1.0-1.0-1.0-0.9-1.0-0.9-0.9-1.0-1.0
Pavlov. Cond. latency score0.70.91.3-1.1-0.4-1.01.0-1.0-1.1-0.8-0.9-1.0-1.0-1.0-0.9-1.1-0.9-0.8-0.9-1.0
Pavlov. Cond. lever contacts0.50.71.0-0.8-0.0-0.80.8-0.8-0.8-0.7-0.9-1.0-1.0-1.0-0.8-0.9-0.8-1.0-0.9-1.0
Pavlov. Cond. magazine entry number0.70.91.31.00.51.0-1.01.01.10.90.80.90.90.90.91.10.81.00.90.9
Pavlov. Cond. intertrial magazine entries0.30.51.10.91.00.8-0.80.80.80.70.40.50.50.50.60.90.60.20.50.4
Pavlov. Cond. lever-magazine prob. diff.0.70.91.3-1.1-0.4-1.11.1-1.0-1.1-0.9-0.9-1.0-1.0-1.0-0.9-1.1-0.9-0.9-1.0-1.0
Pavlov. Cond. response bias1.52.02.7-1.3-0.3-1.31.3-1.4-1.3-1.3-1.5-1.6-1.6-1.6-1.4-1.4-1.4-1.6-1.6-1.7
Time in closed arm before self-admin0.30.41.00.1-0.60.2-0.20.50.20.50.40.90.90.90.70.20.60.50.91.0
Time in closed arm after self-admin0.20.21.0-0.00.30.0-0.0-0.3-0.0-0.4-0.6-0.5-0.5-0.5-0.4-0.1-0.4-1.0-0.5-0.6
Time in open arm before self-admin0.10.10.2-0.4-0.4-0.50.5-0.4-0.5-0.4-0.2-0.4-0.4-0.4-0.3-0.5-0.20.2-0.2-0.3
Time in open arm after self-admin1.11.22.11.00.80.9-0.91.11.01.11.31.11.11.11.11.01.11.51.01.0
Bone: periosteal estimation0.20.40.9-0.1-0.3-0.10.10.3-0.10.60.50.90.90.90.7-0.10.60.60.90.9
Bone: periosteal perimeter0.20.41.1-1.0-1.0-1.01.0-0.7-1.0-0.4-0.4-0.1-0.1-0.1-0.3-1.1-0.4-0.2-0.2-0.0
Bone: post-yield work0.60.91.10.91.00.9-0.90.80.91.01.01.01.01.01.00.91.00.90.90.8
Progressive ratio test 1 active lever presses0.20.20.80.40.90.4-0.4-0.10.3-0.10.1-0.5-0.5-0.5-0.30.30.0-0.2-0.5-0.7
Progressive ratio test 1 breakpoint0.20.20.80.50.90.4-0.4-0.00.4-0.10.1-0.5-0.5-0.5-0.20.30.1-0.2-0.5-0.6
Progressive ratio test 1 inactive lever presses0.20.30.7-0.30.1-0.30.3-0.5-0.3-0.6-0.4-0.7-0.7-0.7-0.6-0.2-0.3-0.8-0.6-0.8
Progressive ratio test 2 active lever presses0.30.30.90.20.90.3-0.3-0.20.2-0.30.1-0.9-0.9-0.9-0.50.1-0.10.1-0.7-0.9
Progressive ratio test 2 breakpoint0.30.41.00.20.90.2-0.2-0.30.1-0.4-0.0-1.0-1.0-1.0-0.50.1-0.20.0-0.7-1.0
Progressive ratio test 2 inactive lever presses0.10.10.4-0.2-0.1-0.20.2-0.3-0.2-0.4-0.0-0.6-0.6-0.6-0.4-0.2-0.10.2-0.4-0.4
Incentive Sensitization - Responses0.30.41.30.71.10.8-0.80.40.70.20.6-0.4-0.4-0.40.10.70.30.9-0.0-0.3
Incentive Sensitization - Breakpoint0.20.20.90.50.90.6-0.60.20.50.10.4-0.5-0.5-0.5-0.00.60.20.7-0.1-0.4
Sum of active levers in priming session hrs 5-60.00.00.10.20.10.2-0.20.20.20.1-0.10.10.10.10.10.10.1-0.30.20.1
Progressive ratio0.50.71.61.20.71.3-1.30.81.20.60.80.60.60.60.51.20.40.90.30.4
Food seeking constrained by brief footshock0.20.20.8-0.2-0.9-0.10.1-0.5-0.1-0.6-0.6-0.4-0.4-0.4-0.5-0.2-0.5-0.7-0.5-0.3
Seeking ratio, punishment vs. effort0.50.71.3-1.0-1.1-1.01.0-0.8-0.9-0.7-0.9-0.5-0.5-0.5-0.6-0.9-0.6-1.2-0.4-0.4
Retroperitoneal fat weight0.52.34.21.91.82.0-2.01.52.01.41.41.11.11.11.32.11.40.81.00.9
Reaction time number correct0.61.14.11.52.01.5-1.51.01.40.90.90.40.40.40.71.31.00.40.40.1
Reaction time mean minus median0.30.70.9-0.9-0.2-0.90.9-0.9-0.9-0.8-0.8-0.9-0.9-0.9-0.8-0.7-0.8-0.9-0.9-1.0
Reaction time mean minus median AUC0.10.10.4-0.6-0.6-0.60.6-0.3-0.60.00.10.30.30.30.1-0.50.00.00.20.3
Reaction time num false alarms0.30.41.90.71.40.6-0.60.50.60.60.70.20.20.20.50.50.60.80.2-0.0
Reaction time num false alarms AUC0.30.52.40.91.60.8-0.80.60.70.60.70.10.10.10.50.70.60.80.1-0.0
Reaction time trials correct on left0.61.14.11.52.01.5-1.51.01.40.90.90.40.40.40.71.31.00.40.40.1
Reaction time trials on left0.61.13.91.52.01.4-1.41.01.40.90.90.40.40.40.81.21.00.40.40.2
Reaction time mean0.10.10.3-0.4-0.2-0.40.4-0.0-0.30.20.20.30.30.30.2-0.20.10.60.30.3
Reaction time mean AUC0.10.10.4-0.4-0.2-0.40.40.0-0.30.20.30.40.40.40.3-0.20.20.60.40.4
Median of all reaction times0.20.31.0-0.0-0.0-0.00.00.40.10.60.60.80.80.80.70.10.51.00.80.8
Reaction time omissions0.20.31.0-0.8-1.0-0.80.8-0.5-0.7-0.5-0.5-0.3-0.3-0.3-0.4-0.6-0.5-0.2-0.1-0.1
Reaction time false alarm rate0.00.10.40.10.30.1-0.10.10.10.30.30.20.20.20.30.10.20.60.20.2
Reaction time premature initiation rate0.81.21.8-0.8-0.3-0.80.8-1.1-0.9-1.1-1.1-1.3-1.3-1.3-1.2-0.8-1.2-1.2-1.3-1.4
Reaction time premature initiations0.40.72.0-0.10.8-0.10.1-0.6-0.2-0.7-0.7-1.2-1.2-1.2-0.9-0.2-0.7-1.1-1.2-1.4
Std. dev. reaction times0.10.20.6-0.8-0.2-0.70.7-0.6-0.7-0.3-0.3-0.3-0.3-0.3-0.4-0.5-0.4-0.1-0.4-0.4
Reaction time trials completed0.61.13.91.52.01.4-1.41.01.40.90.90.40.40.40.81.21.00.40.40.2
Reaction time trials AUC0.61.24.71.62.21.5-1.51.01.50.90.90.40.40.40.71.31.00.50.30.1
Run reversals in cocaine runway, females0.60.61.1-0.8-1.1-0.70.7-0.9-0.9-0.8-0.9-0.6-0.6-0.6-0.8-1.0-0.7-0.9-0.7-0.5
Run reversals in cocaine runway, males2.12.24.6-1.2-1.5-1.51.5-1.4-1.5-1.5-1.8-1.2-1.2-1.2-1.4-1.7-1.4-2.1-1.3-1.1
Latency to leave start box in cocaine runway0.70.82.1-1.3-1.4-1.21.2-0.7-1.2-0.7-0.8-0.6-0.6-0.6-0.6-1.2-0.9-0.0-0.3-0.2
Latency to leave start box in cocaine runway, F0.30.41.8-0.7-1.3-0.60.60.1-0.60.00.10.20.20.20.2-0.7-0.11.00.70.7
Latency to leave start box in cocaine runway, M1.71.62.2-1.1-0.5-1.11.1-1.2-1.1-1.3-1.4-1.4-1.4-1.4-1.4-0.9-1.4-1.4-1.5-1.5
Std. dev. time between licks in bursts0.91.22.2-1.3-1.0-1.51.5-1.1-1.5-1.0-0.8-0.8-0.8-0.8-0.9-1.5-1.0-0.5-0.9-0.8
Total sessions with >9 infusions0.20.30.8-0.20.3-0.30.3-0.4-0.3-0.4-0.3-0.9-0.9-0.9-0.5-0.2-0.2-0.4-0.6-0.7
Short access day 1 total inactive lever presses0.30.30.7-0.5-0.2-0.50.5-0.6-0.4-0.6-0.3-0.8-0.8-0.8-0.7-0.3-0.4-0.3-0.6-0.7
Short access day 10 total inactive lever presses0.00.10.40.30.60.4-0.40.20.40.10.2-0.3-0.3-0.30.10.50.10.2-0.1-0.1
Short access day 1 total infusions0.30.40.6-0.6-0.3-0.70.7-0.7-0.6-0.6-0.5-0.7-0.7-0.7-0.7-0.5-0.4-0.7-0.6-0.7
Short access day 10 total infusions0.10.10.30.20.60.3-0.3-0.10.2-0.20.0-0.5-0.5-0.5-0.30.20.1-0.3-0.4-0.5
Short access total infusions0.20.30.8-0.30.1-0.30.3-0.5-0.3-0.5-0.3-0.9-0.9-0.9-0.6-0.3-0.3-0.2-0.7-0.7
Short access day 1 locomotion1.31.72.3-1.2-0.6-1.21.2-1.4-1.2-1.3-1.2-1.5-1.5-1.5-1.3-1.1-1.0-1.5-1.3-1.4
Short access day 10 total locomotion3.66.610.9-2.0-0.7-2.02.0-2.6-2.1-2.7-2.5-3.3-3.3-3.3-2.8-2.0-2.5-2.4-3.0-3.1
Short access total locomotion2.12.64.3-1.3-0.5-1.41.4-1.6-1.4-1.6-1.6-2.1-2.1-2.1-1.7-1.3-1.3-1.6-1.8-1.9
One hour access (0.3 mA shock)0.10.10.30.30.50.3-0.30.10.30.10.4-0.1-0.1-0.10.10.30.40.4-0.2-0.1
Compulsive drug intake0.81.02.40.4-0.40.2-0.20.90.41.00.91.31.31.31.20.41.01.31.21.5
One hour access (shock baseline)0.30.51.3-0.20.5-0.10.1-0.7-0.2-0.7-0.4-1.0-1.0-1.0-0.8-0.3-0.5-0.7-1.1-1.2
Social response proportion1.01.12.0-1.3-1.4-1.31.3-1.0-1.2-1.1-1.0-0.8-0.8-0.8-1.0-1.1-1.2-0.5-0.9-0.7
Social responses7.79.912.6-3.5-2.9-3.53.5-3.3-3.5-3.1-3.1-3.0-3.0-3.0-3.0-3.4-3.2-2.6-2.9-2.7
Social time0.40.60.90.80.40.9-0.91.00.90.70.60.70.70.70.70.90.60.70.60.8
Soleus weight8.124.027.34.84.04.7-4.75.14.75.25.05.05.05.05.24.75.24.75.04.8
Bone: stiffness2.33.85.11.51.11.5-1.51.91.52.12.12.32.32.32.21.52.12.12.22.2
Tibialis anterior weight1.13.74.32.11.62.0-2.02.01.92.01.92.02.02.02.01.92.11.51.91.8
Time to tail flick, vehicle, before self-admin0.20.21.0-0.4-0.6-0.40.4-0.3-0.4-0.3-0.7-0.1-0.1-0.1-0.2-0.3-0.3-1.0-0.2-0.1
Time to tail flick, vehicle, after self-admin0.30.41.10.10.80.1-0.1-0.40.0-0.5-0.5-0.7-0.7-0.7-0.60.1-0.6-1.0-0.9-1.1
Time to tail flick, test, before self-admin0.50.51.1-0.9-1.0-0.90.9-0.7-0.9-0.6-0.6-0.3-0.3-0.3-0.5-1.0-0.5-0.4-0.4-0.3
Time to tail flick, test, after self-admin0.10.10.7-0.3-0.3-0.30.3-0.3-0.3-0.3-0.5-0.2-0.2-0.2-0.3-0.3-0.3-0.8-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.60.52.31.01.51.1-1.10.61.00.50.70.10.10.10.31.00.40.40.0-0.2
Delta time to tail flick, test, before/after SA0.20.20.80.50.90.5-0.50.20.50.1-0.0-0.2-0.2-0.2-0.10.60.0-0.4-0.3-0.4
Tibia length0.82.12.9-1.4-0.9-1.41.4-1.6-1.4-1.5-1.5-1.6-1.6-1.6-1.5-1.4-1.6-1.1-1.7-1.6
Ambulatory time before self-admin0.10.10.30.20.10.2-0.20.40.20.40.40.40.40.40.50.20.50.60.60.6
Ambulatory time after self-admin0.00.00.0-0.2-0.2-0.10.1-0.0-0.10.0-0.1-0.0-0.0-0.00.0-0.1-0.00.00.10.1
Bone: tissue strength1.81.82.81.10.61.1-1.11.41.21.41.31.51.51.51.51.21.31.71.51.5
Total heroin consumption1.61.93.0-1.3-1.4-1.31.3-1.4-1.3-1.4-1.6-1.3-1.3-1.3-1.4-1.4-1.4-1.7-1.3-1.2
Bone: trabecular number0.61.02.7-1.3-1.6-1.31.3-1.0-1.3-0.8-0.8-0.4-0.4-0.4-0.7-1.4-0.8-0.5-0.4-0.3
Bone: trabecular spacing1.01.45.61.72.41.7-1.71.11.60.80.70.10.10.10.61.70.80.40.1-0.1
Bone: trabecular thickness0.91.25.3-1.4-2.3-1.41.4-0.3-1.30.0-0.00.70.70.70.3-1.5-0.11.00.71.2
Bone: trabecular tissue density1.52.13.01.71.31.7-1.71.61.71.41.41.31.31.31.41.71.41.41.21.3
Water consumed over 24 hours0.60.71.20.70.30.6-0.60.90.61.00.81.11.11.11.00.50.90.91.11.1
Number of responses in last shaping day1.41.62.8-0.8-0.2-0.90.9-1.2-0.9-1.3-1.2-1.7-1.7-1.7-1.3-0.9-1.1-1.5-1.4-1.6