Hub : Genes

LOC108350383

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC intron excision ratio chr3_68231297_68231717 0.13 0.09 1.0e-04 0.08 0.06 0.07 0.07 2.6e-04 1.2e-03 4.6e-04 5.9e-04
2 pVTA intron excision ratio chr3_68231369_68231717 0.03 0.03 3.1e-03 0.01 0.02 0 0.01 5.0e-02 6.5e-03 1.3e-01 7.8e-02
3 Brain intron excision ratio chr3_68231297_68231717 0.08 0.06 1.5e-07 0.06 0.08 0.08 0.08 3.3e-06 6.6e-08 1.1e-07 7.7e-08
4 Brain intron excision ratio chr3_68231369_68231717 0.04 0.03 2.1e-04 0.02 0.03 0.03 0.02 5.6e-03 1.2e-03 1.9e-03 3.3e-03
5 BLA intron excision ratio chr3_68231369_68231717 0.06 0.05 2.7e-03 0.03 0.03 0.03 0.02 1.2e-02 1.3e-02 7.0e-03 3.1e-02
6 PL gene expression LOC108350383 0.03 0.02 4.8e-04 0.02 0.03 0.02 0.02 1.3e-03 8.5e-04 4.5e-03 3.6e-03
7 IC intron excision ratio chr3_68231369_68231717 0.13 0.12 7.5e-04 0.03 0.05 0.04 0.04 2.7e-02 3.8e-03 8.0e-03 6.9e-03
8 OFC intron excision ratio chr3_68231297_68231717 0.13 0.09 7.3e-03 0.09 0.07 0.06 0.08 3.7e-03 8.8e-03 1.5e-02 6.8e-03
9 LHb gene expression LOC108350383 0.27 0.15 4.0e-05 0.14 0.16 0.17 0.17 4.4e-04 1.3e-04 8.2e-05 6.7e-05
10 NAcc intron excision ratio chr3_68231297_68231717 0.02 0.02 2.7e-04 0.03 0.03 0.03 0.03 8.8e-05 8.5e-05 7.3e-05 1.0e-04
11 BLA intron excision ratio chr3_68231297_68231717 0.1 0.06 2.8e-05 0.08 0.07 0.07 0.07 7.3e-05 9.1e-05 9.1e-05 9.0e-05
12 PL intron excision ratio chr3_68231369_68231717 0.04 0.03 4.5e-05 0.03 0.04 0.02 0.03 2.4e-04 7.7e-05 1.5e-03 2.9e-04
13 Brain gene expression LOC108350383 0.04 0.03 6.5e-04 0.05 0.03 0.02 0.04 2.7e-05 4.2e-04 5.7e-03 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.30.62.40.8-0.40.6-0.6-1.50.5-0.60.40.20.61.6-0.60.0
Area under the delay curve0.20.20.4-0.30.6-0.40.40.2-0.40.4-0.4-0.6-0.4-0.20.3-0.5
BMI with tail0.00.10.40.6-0.50.3-0.1-0.20.1-0.50.10.10.2-0.00.10.1
BMI without tail0.41.31.81.3-1.31.2-1.1-0.91.1-1.41.21.11.20.9-1.01.1
Body weight0.31.44.52.1-1.51.3-1.1-1.10.9-1.30.90.90.90.8-0.70.9
Weight adjusted by age0.81.32.1-1.11.5-1.31.21.4-1.11.2-1.0-1.1-1.0-0.90.9-0.9
Bone surface1.12.03.71.5-1.31.5-1.4-1.91.4-1.31.21.11.31.9-1.40.9
Bone volume0.71.32.91.5-1.01.2-1.1-1.70.9-1.00.80.61.01.6-0.90.5
Breakpoint value in progressive ratio session7.18.510.7-2.32.9-2.92.93.0-3.03.0-3.0-2.9-3.1-3.32.9-2.7
Number of licking bursts0.00.00.20.1-0.10.1-0.10.30.2-0.10.20.10.1-0.4-0.20.2
Context. condit. distance diff. score0.00.10.40.3-0.00.1-0.1-0.40.00.0-0.0-0.10.10.6-0.1-0.0
Locomotion velocity, session 10.30.40.7-0.3-0.50.5-0.6-0.10.7-0.60.90.80.70.2-0.80.7
Locomotion distance, session 10.10.10.3-0.2-0.10.2-0.3-0.50.3-0.20.30.30.30.6-0.40.3
Locomotion velocity, session 21.72.02.8-1.21.7-1.51.41.1-1.41.5-1.5-1.5-1.4-1.11.2-1.6
Locomotion distance, session 20.10.20.80.9-0.40.5-0.5-0.60.3-0.30.20.30.30.3-0.40.2
Locomotion velocity, session 30.70.81.2-0.71.1-0.90.91.1-0.90.9-1.0-0.8-1.0-0.90.8-0.8
Locomotion distance, session 30.30.30.40.3-0.40.5-0.5-0.40.6-0.60.60.60.50.5-0.60.7
Stereotopy head waving bouts, day 30.30.41.51.2-0.80.7-0.6-0.70.4-0.50.40.40.40.6-0.30.4
Stereotopy head waving duration, day 30.10.10.60.8-0.30.4-0.3-0.50.1-0.10.00.10.10.5-0.10.1
Locomotion velocity, session 70.00.00.1-0.30.1-0.0-0.0-0.30.0-0.00.0-0.10.10.4-0.10.1
Locomotion distance, session 70.00.00.00.1-0.00.0-0.0-0.1-0.00.0-0.0-0.00.00.10.00.0
Stereotopy head waving bouts, day 70.10.20.40.6-0.40.4-0.4-0.50.4-0.40.40.30.30.4-0.30.4
Stereotopy head waving duration, day 70.30.30.50.7-0.60.6-0.6-0.70.5-0.50.50.50.50.7-0.60.5
Locomotion velocity, session 80.00.00.10.20.2-0.00.10.0-0.10.2-0.2-0.2-0.2-0.10.0-0.3
Locomotion distance, session 80.00.10.10.30.2-0.20.2-0.2-0.30.3-0.4-0.3-0.30.10.3-0.3
Degree of sensitization distance0.70.81.1-0.30.7-0.80.80.7-1.00.9-1.0-1.0-0.9-0.91.0-1.0
Degree of sensitization stereotypy0.00.00.00.10.1-0.10.10.0-0.10.0-0.1-0.1-0.1-0.10.1-0.0
Conditioned locomotion0.80.91.6-0.31.1-0.90.90.5-1.01.1-1.3-1.1-1.1-0.60.9-1.1
Cocaine response after cond. corrected7.38.811.7-1.82.8-2.93.03.0-3.13.0-3.1-3.1-3.2-3.43.1-2.9
Cocaine response after cond. not corrected4.55.37.6-0.82.1-2.02.22.3-2.42.4-2.5-2.5-2.6-2.82.5-2.4
Cocaine response before conditioning2.63.24.52.1-1.92.0-1.9-2.01.7-1.61.51.51.61.9-1.71.4
Saline control response0.20.30.5-0.30.5-0.50.50.7-0.50.5-0.5-0.5-0.6-0.70.5-0.5
Bone: connectivity density0.30.52.40.5-0.30.6-0.6-1.40.6-0.50.40.30.71.5-0.70.1
Bone: cortical apparent density0.30.51.40.6-0.50.6-0.6-1.10.5-0.60.50.50.61.2-0.60.6
Bone: cortical area4.57.09.73.1-2.92.8-2.7-2.72.5-2.62.52.42.52.6-2.32.4
Bone: cortical porosity2.32.53.71.9-1.71.7-1.6-1.81.5-1.61.51.41.51.6-1.51.3
Bone: cortical porosity4.85.25.92.3-2.42.4-2.3-2.42.3-2.42.32.12.32.2-2.22.0
Bone: cortical thickness3.35.56.92.6-2.62.4-2.3-2.62.2-2.42.32.12.32.5-2.02.1
Bone: cortical thickness6.37.48.82.8-3.02.8-2.7-2.92.6-2.82.62.62.73.0-2.42.6
Bone: cortical tissue density0.30.41.30.5-0.40.5-0.5-1.00.5-0.50.40.40.51.1-0.50.5
Condit. Reinf. active minus inactive responses6.87.69.12.9-2.82.9-2.7-3.02.7-2.92.62.62.73.0-2.62.6
Condit. Reinf. active-inactive response ratio2.72.94.21.5-1.71.7-1.6-1.91.6-1.81.61.61.72.0-1.61.6
Condit. Reinf. active responses5.36.68.12.6-2.52.6-2.6-2.82.5-2.62.42.42.52.9-2.62.4
Condit. Reinf. inactive responses1.51.82.11.4-1.31.4-1.4-1.31.4-1.21.41.31.31.3-1.41.3
Incentive salience index mean6.47.99.72.9-2.82.9-2.8-3.12.8-2.92.62.62.83.1-2.72.6
Condit. Reinf. lever presses0.91.32.31.1-1.01.0-1.1-1.41.1-1.11.11.01.21.5-1.11.0
Condit. Reinf. active minus inactive responses3.34.25.92.2-2.02.2-2.2-2.42.0-1.91.91.82.02.3-2.11.7
Condit. Reinf. active-inactive response ratio2.22.63.81.7-1.51.6-1.7-1.91.6-1.41.51.41.61.8-1.71.3
Condit. Reinf. active responses2.94.05.22.3-2.22.1-2.1-2.31.9-1.91.81.82.02.2-1.81.6
Condit. Reinf. inactive responses0.10.10.50.7-0.40.3-0.2-0.20.0-0.10.10.10.10.20.1-0.0
Condit. Reinf. lever presses3.14.38.32.9-2.12.3-2.2-2.31.9-1.81.81.61.92.1-2.01.6
Condit. Reinf. lever reinforcers received1.92.73.91.8-1.71.7-1.7-2.01.5-1.41.51.41.61.9-1.51.2
Conditioned reinforcement - actives1.22.03.11.8-1.71.5-1.4-1.21.4-1.51.11.61.40.9-1.21.5
Conditioned reinforcement - inactives0.10.10.9-0.0-0.30.0-0.10.50.1-0.00.20.40.1-0.90.00.6
Conditioned locomotion0.10.20.80.7-0.20.10.10.3-0.20.2-0.4-0.2-0.2-0.90.4-0.3
Patch foraging indifference point 0 sec0.00.10.40.6-0.30.10.00.4-0.0-0.20.10.20.1-0.40.2-0.1
Patch foraging indifference point AUC0.20.20.9-0.70.30.2-0.5-0.50.50.10.30.20.40.7-0.90.3
Delay disc. indifference point, 0s delay0.00.00.10.3-0.10.0-0.00.1-0.00.00.2-0.0-0.0-0.00.10.1
Delay disc. indifference point, 16s delay0.10.10.20.5-0.30.3-0.2-0.40.2-0.40.30.20.30.5-0.20.3
Delay disc. indifference point, 2s delay0.10.20.3-0.2-0.20.2-0.3-0.30.5-0.50.40.40.50.4-0.50.6
Delay disc. indifference point, 24s delay0.50.51.1-1.10.9-0.70.60.3-0.70.9-0.8-0.8-0.6-0.00.5-0.8
Delay disc. indifference point, 4s delay0.60.61.1-1.11.0-0.90.80.5-0.70.7-0.6-0.8-0.8-0.60.6-0.8
Delay disc. indifference point, 8s delay0.20.20.4-0.00.6-0.40.50.1-0.50.5-0.6-0.6-0.5-0.30.4-0.5
Indifference point function ln k0.10.30.50.7-0.70.3-0.20.20.3-0.70.70.70.4-0.4-0.10.6
Indifference point function log k0.10.30.50.7-0.70.3-0.20.20.3-0.70.70.70.4-0.4-0.10.6
Patch foraging total patch changes 0 sec0.10.20.70.30.1-0.30.40.8-0.30.1-0.1-0.1-0.2-0.80.5-0.4
Patch foraging total patch changes 12 sec1.21.62.61.6-1.21.5-1.4-0.91.3-1.21.31.11.20.8-1.41.1
Patch foraging total patch changes 18 sec1.01.52.31.5-1.21.4-1.4-1.11.3-1.11.21.11.20.9-1.40.9
Patch foraging total patch changes 24 sec0.71.22.41.5-1.21.3-1.2-1.01.1-1.01.10.91.00.9-1.10.7
Patch foraging total patch changes 6 sec0.10.20.3-0.50.5-0.40.40.5-0.40.5-0.6-0.5-0.4-0.40.4-0.4
Patch foraging time to switch 0 sec0.10.30.9-0.00.1-0.40.60.3-0.70.3-0.8-0.5-0.5-0.31.0-0.8
Patch foraging water rate 0 sec1.63.34.62.1-1.82.0-1.9-1.41.9-1.81.91.81.71.2-1.92.0
Patch foraging water rate 12 sec1.73.54.92.0-2.02.0-1.9-1.31.9-1.92.12.01.71.0-1.82.2
Patch foraging water rate 18 sec3.35.26.32.0-2.32.3-2.3-2.32.3-2.32.32.32.32.0-2.32.5
Patch foraging water rate 24 sec2.53.55.01.3-1.71.8-1.9-1.71.9-1.92.12.01.91.7-2.02.2
Patch foraging water rate 6 sec3.75.47.21.7-2.52.3-2.4-1.82.5-2.52.72.62.41.4-2.42.6
Seeking ratio, delayed vs. immediate footshock0.20.30.91.0-0.70.6-0.5-0.50.4-0.40.80.40.30.3-0.30.4
Distance traveled before self-admin2.73.55.62.1-2.42.0-1.9-1.21.8-1.92.21.91.81.2-1.51.9
Distance traveled after self-admin2.22.73.61.9-1.91.7-1.6-1.61.5-1.61.81.41.71.7-1.41.5
Extensor digitorum longus weight0.20.71.11.0-1.10.9-0.9-0.60.8-0.80.90.90.80.4-0.71.0
Bone: elastic displacement0.10.10.4-0.50.2-0.40.40.6-0.30.1-0.1-0.1-0.2-0.40.4-0.0
Bone: elastic work0.00.00.0-0.2-0.2-0.00.0-0.00.1-0.20.20.20.20.10.00.2
Bone: endosteal estimation0.41.01.31.1-0.91.1-1.1-1.11.0-0.90.80.90.80.9-1.10.9
Bone: endosteal perimeter0.71.52.01.0-1.21.3-1.4-1.21.3-1.11.11.21.11.1-1.41.1
Epididymis fat weight8.027.330.9-5.55.5-5.65.55.2-5.25.0-5.1-5.0-5.0-5.05.1-5.2
Delta time in closed arm before/after self-admin1.51.41.7-0.71.2-1.11.21.1-1.31.2-1.2-1.3-1.3-1.01.2-1.3
Delta time in open arm before/after self-admin1.91.92.80.8-1.41.3-1.3-1.21.4-1.41.51.41.71.6-1.41.2
Diff in mean of infusions in LGA sessions11.413.916.8-3.03.9-3.83.93.3-3.93.7-4.1-4.0-3.9-3.13.8-3.9
Delay discount exponential model param0.20.30.50.6-0.70.6-0.5-0.30.5-0.50.50.60.50.3-0.40.6
Extinction: sum of active levers before priming0.40.41.90.70.1-0.20.41.1-0.50.4-0.5-0.4-0.8-1.40.60.0
Active lever presses in extinction session 60.20.21.81.3-0.50.3-0.10.3-0.1-0.2-0.10.1-0.1-0.30.30.2
Bone: final force4.47.09.52.1-2.72.6-2.7-3.02.6-2.62.62.52.83.1-2.62.4
Bone: final moment4.26.78.92.0-2.62.6-2.6-2.92.6-2.62.62.52.73.0-2.52.4
Food consumed during 24 hour testing period0.40.63.31.8-0.81.0-0.8-0.50.6-0.60.50.40.40.2-0.60.5
Glucose0.40.61.81.3-0.90.8-0.7-0.60.7-0.70.80.80.70.4-0.60.7
Heart weight0.30.50.70.2-0.70.6-0.6-0.50.8-0.80.80.80.80.5-0.70.8
Delay discount hyperbolic model param0.20.20.50.6-0.70.5-0.5-0.20.5-0.50.50.60.40.3-0.30.5
Intermittent access intake day 1-15 change2.85.88.41.9-2.62.4-2.4-1.82.5-2.62.72.92.51.8-2.32.5
Intermittent access intake escalation2.65.37.71.8-2.52.3-2.3-1.72.4-2.42.62.82.41.8-2.32.4
Intermittent access intake escalation 23.43.96.21.3-2.01.9-1.9-1.52.1-2.12.32.52.11.6-2.02.1
Intermitt. access day 1 inactive lever presses0.62.23.5-1.91.4-1.61.51.7-1.41.5-1.4-1.3-1.4-1.61.4-1.2
Intermitt. access day 15 inactive lever presses0.10.20.8-0.90.3-0.40.30.4-0.30.4-0.0-0.1-0.2-0.50.3-0.3
Intermitt. access escalation Index0.30.41.3-0.1-0.30.4-0.5-1.00.6-0.70.60.50.81.1-0.70.4
Intermittent access day 1 total infusions0.20.30.50.20.4-0.40.50.3-0.60.5-0.7-0.7-0.7-0.60.7-0.4
Intermittent access day 15 total infusions1.21.82.61.6-1.51.5-1.4-1.01.3-1.31.31.51.20.9-1.21.4
Intermittent access terminal intake (last 3 days)2.02.63.21.8-1.81.7-1.6-1.31.6-1.61.61.81.51.2-1.51.7
Intermittent access total infusions0.50.61.71.3-0.90.9-0.8-0.60.7-0.70.60.80.50.4-0.60.8
Intermittent access day 1 locomotion2.32.94.0-0.91.4-1.61.71.7-1.81.8-1.9-1.8-1.8-2.01.9-1.7
Intermittent access day 15 total locomotion0.10.20.70.9-0.70.6-0.5-0.10.3-0.20.10.40.3-0.2-0.20.3
Intermittent access total locomotion0.10.10.40.6-0.20.10.00.2-0.10.1-0.2-0.1-0.1-0.40.3-0.0
Intermittent access standard deviation1.12.23.61.8-1.91.6-1.5-0.91.5-1.41.71.71.40.8-1.21.4
Left kidney weight0.41.72.91.7-1.41.5-1.5-1.01.4-1.21.41.21.20.6-1.41.2
Right kidney weight1.04.65.52.2-2.32.3-2.3-1.92.2-2.22.32.12.11.7-2.12.2
Cocaine induced anxiety0.30.41.2-1.10.9-0.90.80.2-0.60.5-0.6-0.5-0.5-0.20.5-0.4
Post-drug Anxiety0.50.51.00.2-0.70.6-0.6-0.80.7-0.81.00.90.80.5-0.70.7
Baseline Anxiety1.92.23.81.7-1.91.7-1.6-1.01.5-1.41.71.41.50.8-1.21.3
Tail length1.14.35.92.4-2.12.4-2.3-2.02.1-1.92.01.91.91.8-2.21.9
Length with tail0.73.05.92.4-1.92.0-1.9-1.71.7-1.61.51.61.51.5-1.61.5
Length without tail0.92.83.61.9-1.91.7-1.7-1.91.6-1.71.41.61.61.7-1.41.5
Times rat made contact with spout4.65.36.6-1.12.3-2.12.32.3-2.42.3-2.4-2.4-2.4-2.62.3-2.5
Lifetime Intake0.50.62.61.6-0.90.9-0.7-0.60.6-0.70.50.60.40.4-0.50.7
Liver weight, left0.50.81.31.1-1.11.0-0.9-0.80.8-0.90.70.90.90.8-0.70.9
Liver weight, right0.10.10.40.4-0.1-0.10.20.6-0.40.3-0.2-0.3-0.4-0.70.5-0.3
Locomotor activity2.64.15.12.1-2.22.3-2.2-2.12.0-1.91.81.91.91.9-2.01.7
Locomotor testing distance5.19.210.52.9-3.23.2-3.2-3.03.1-3.02.93.13.02.9-3.02.9
Locomotor testing rearing4.89.711.02.7-3.33.3-3.2-3.13.1-3.03.13.23.13.1-3.03.1
Locomotion in novel chamber1.21.62.80.41.0-0.91.10.8-1.41.3-1.4-1.6-1.3-1.21.4-1.7
Locomotion in novel chamber post-restriction0.81.32.50.9-1.20.9-0.9-1.40.9-1.21.21.11.21.6-0.81.1
Fecal boli incidents, locomotor time 10.20.31.9-1.40.0-0.30.00.10.3-0.30.50.50.50.5-0.30.5
Change in fecal boli incidents, locomotor task0.10.10.90.9-0.30.3-0.2-0.20.00.1-0.10.0-0.10.00.0-0.1
Time >=10cm from walls, locomotor time 10.50.50.70.6-0.80.7-0.7-0.80.6-0.70.70.70.70.8-0.60.6
Bouts of movement, locomotor time 12.42.85.7-2.41.8-1.91.81.8-1.61.5-1.0-1.5-1.5-1.41.6-1.6
Total resting periods, locomotor time 12.02.25.3-2.31.6-1.71.71.6-1.41.3-0.9-1.3-1.3-1.21.4-1.4
Rest time, locomotor task time 11.82.34.2-2.01.7-1.71.61.5-1.41.4-1.2-1.5-1.3-1.31.4-1.4
Distance moved, locomotor task time 12.33.45.82.4-2.02.0-1.8-1.81.7-1.91.51.81.61.9-1.61.7
Vertical activity count, locomotor time 10.20.61.11.1-0.80.8-0.7-0.70.7-0.90.50.90.60.7-0.70.8
Time >=10cm from walls, locomotor time 20.00.10.40.7-0.30.4-0.3-0.10.10.0-0.10.1-0.1-0.2-0.1-0.1
Bouts of movement, locomotor time 21.01.52.9-1.71.1-1.41.51.5-1.30.9-0.6-1.0-1.0-1.41.4-1.0
Total resting periods, locomotor time 20.91.63.6-1.91.2-1.51.51.5-1.30.9-0.6-1.0-1.0-1.31.4-1.1
Rest time, locomotor task time 20.50.62.0-1.40.8-0.90.90.9-0.70.5-0.4-0.6-0.5-0.60.7-0.5
Distance moved, locomotor task time 20.91.03.01.7-1.11.2-1.1-0.90.9-0.90.70.90.71.0-0.80.8
Vertical activity count, locomotor time 20.00.00.30.10.2-0.10.20.2-0.10.1-0.5-0.1-0.2-0.00.1-0.1
Light reinforcement 10.20.40.80.1-0.60.6-0.7-0.20.8-0.70.90.70.80.3-0.80.7
Light reinforcement 20.30.51.2-0.5-0.20.5-0.6-0.70.8-0.70.80.60.80.9-1.10.6
Bone: marrow area0.51.11.41.2-1.01.2-1.2-1.21.1-0.90.80.90.81.0-1.21.0
Bone: maximum diameter1.52.85.82.4-1.91.9-1.8-1.61.6-1.61.41.51.41.3-1.51.6
Bone: maximum force4.27.49.42.4-2.82.7-2.7-3.02.7-2.72.72.62.83.1-2.62.5
Bone: maximum moment4.17.28.82.4-2.82.7-2.7-2.92.7-2.72.72.72.73.0-2.62.5
Mean time between licks in bursts0.00.10.40.6-0.20.3-0.30.10.2-0.00.2-0.10.1-0.3-0.20.1
Mean num. licks in bursts1.21.92.6-0.61.4-1.31.41.0-1.51.4-1.6-1.5-1.5-1.11.5-1.6
Cd content in liver0.10.10.2-0.30.3-0.30.30.2-0.30.2-0.3-0.2-0.3-0.40.3-0.2
Co content in liver0.10.10.80.9-0.20.3-0.2-0.40.00.1-0.1-0.1-0.10.20.0-0.1
Cu content in liver0.50.61.2-0.3-0.40.6-0.8-1.00.9-0.70.80.80.90.9-1.10.8
Fe content in liver0.10.11.4-1.20.3-0.40.20.1-0.00.00.10.20.10.0-0.00.2
K content in liver0.50.51.10.4-0.60.8-0.9-0.50.9-0.60.80.70.70.5-1.00.7
Mg content in liver1.31.31.90.8-1.11.2-1.3-0.71.3-1.11.31.21.20.7-1.41.2
Mn content in liver10.111.212.72.8-3.23.5-3.5-3.53.5-3.43.33.33.43.3-3.63.3
Na content in liver4.24.55.41.6-2.22.2-2.3-1.82.3-2.12.32.32.21.7-2.32.3
Rb content in liver1.11.31.51.0-1.21.2-1.2-1.11.2-1.11.11.11.21.1-1.21.1
Se content in liver0.70.91.1-1.01.0-1.01.01.0-0.90.9-0.9-0.8-0.9-0.90.9-0.8
Sr content in liver0.50.40.70.8-0.60.7-0.6-0.70.6-0.60.60.60.60.6-0.50.6
Zn content in liver0.40.41.30.00.4-0.50.60.9-0.70.7-0.6-0.6-0.7-1.10.8-0.6
Bone: minimum diameter0.81.52.01.4-1.41.3-1.3-1.41.2-1.21.11.11.11.2-1.11.0
Time in familiar zone, hab. session 10.10.10.3-0.20.5-0.20.20.3-0.20.6-0.5-0.5-0.4-0.30.1-0.5
Time in novel zone, hab. session 10.40.40.6-0.70.4-0.70.70.7-0.60.4-0.5-0.5-0.5-0.60.8-0.5
Total zone transitions, hab. session 11.52.02.71.5-1.41.5-1.5-1.61.4-1.31.31.31.41.6-1.41.3
Total locomotion distance, hab. session 11.42.02.61.0-1.31.5-1.6-1.51.5-1.21.41.41.41.5-1.61.5
Locomotion velocity, hab. session 11.31.82.20.9-1.21.4-1.5-1.41.4-1.21.31.41.31.4-1.51.4
Time in familiar zone, hab. session 22.42.53.0-1.51.7-1.61.61.4-1.61.7-1.7-1.6-1.6-1.31.6-1.6
Time in novel zone, hab. session 21.61.62.31.5-1.41.3-1.3-1.11.2-1.41.41.31.20.9-1.11.3
Total zone transitions, hab. session 21.01.31.61.1-1.31.2-1.2-1.21.1-1.11.11.11.11.0-1.01.0
Total locomotion distance, hab. session 20.60.81.00.4-0.90.9-0.9-0.80.9-1.01.01.00.90.8-0.91.0
Locomotion velocity, hab. session 20.40.60.80.2-0.80.7-0.8-0.60.8-0.80.90.90.80.7-0.80.9
Novel to familiar place preference ratio0.70.71.2-0.10.6-0.80.90.8-1.00.8-1.0-0.9-0.9-1.01.1-0.9
Novelty place preference0.80.91.3-0.10.6-0.80.90.9-1.00.9-1.0-1.0-1.0-1.11.2-0.9
Time in novel zone, NPP test0.80.81.4-0.10.6-0.80.90.9-1.00.9-1.0-0.9-1.0-1.11.2-0.9
Total zone transitions, NPP test0.10.20.50.3-0.30.4-0.4-0.70.4-0.20.30.30.40.7-0.40.3
Total locomotion distance, NPP test0.81.11.60.6-0.91.0-1.1-1.21.1-1.01.01.01.11.3-1.21.0
Locomotion velocity, NPP test0.91.21.70.6-0.91.1-1.2-1.21.2-1.01.11.11.11.3-1.31.1
Intraocular pressure1.42.02.51.6-1.51.5-1.4-1.41.4-1.51.21.31.41.3-1.41.4
Delta distance traveled before/after self-admin0.50.50.9-0.70.9-0.80.80.3-0.70.7-0.7-0.9-0.6-0.20.6-0.8
Delta ambulatory time before/after self-admin0.20.20.70.3-0.30.4-0.4-0.80.4-0.40.40.20.50.8-0.50.3
Parametrial fat weight2.86.67.8-2.72.7-2.82.72.7-2.62.7-2.4-2.3-2.5-2.62.5-2.1
Pavlov. Cond. lever latency0.40.51.3-1.10.8-0.70.60.8-0.60.6-0.6-0.5-0.6-0.60.5-0.5
Pavlov. Cond. magazine entry latency0.00.00.10.3-0.30.3-0.2-0.30.1-0.20.20.10.20.1-0.00.1
Pavlov. Cond. change in total contacts1.51.62.31.2-1.21.2-1.3-1.51.2-1.21.31.11.31.3-1.21.1
Pavlov. Cond. index score0.50.71.21.1-0.90.8-0.8-1.00.7-0.80.80.70.80.7-0.60.6
Pavlov. Cond. latency score0.40.61.31.1-0.90.8-0.7-0.90.6-0.70.70.50.70.7-0.60.5
Pavlov. Cond. lever contacts0.81.02.21.5-1.11.0-1.0-1.10.9-0.90.90.80.90.8-0.80.8
Pavlov. Cond. magazine entry number0.40.50.7-0.60.7-0.70.70.8-0.70.7-0.8-0.6-0.7-0.70.6-0.6
Pavlov. Cond. intertrial magazine entries0.91.12.31.5-1.11.2-1.1-1.01.0-1.00.80.90.80.9-1.00.9
Pavlov. Cond. lever-magazine prob. diff.0.60.71.21.1-1.00.9-0.8-1.00.8-0.80.80.70.80.8-0.70.7
Pavlov. Cond. response bias0.40.60.80.7-0.80.7-0.7-0.90.7-0.70.80.70.80.7-0.70.7
Pavlov. Cond. lever latency1.72.37.8-2.81.6-1.81.61.8-1.21.2-1.0-1.0-1.1-1.41.2-0.9
Pavlov. Cond. magazine entry latency1.31.62.70.90.9-0.71.00.9-1.31.3-1.6-1.4-1.5-1.41.3-1.6
Pavlov. Cond. change in total contacts0.50.82.91.7-0.81.1-1.0-1.00.8-0.50.50.60.60.7-0.90.3
Pavlov. Cond. index score0.30.43.21.8-0.10.3-0.1-0.1-0.30.4-0.6-0.5-0.5-0.40.3-0.7
Pavlov. Cond. latency score0.40.52.31.50.20.00.20.2-0.50.7-0.9-0.7-0.7-0.60.5-1.0
Pavlov. Cond. lever contacts1.62.17.82.8-1.51.7-1.5-1.81.2-1.10.90.91.11.4-1.20.8
Pavlov. Cond. magazine entry number1.41.72.8-0.5-1.10.9-1.1-1.01.4-1.51.61.51.61.4-1.31.7
Pavlov. Cond. intertrial magazine entries2.13.23.90.8-1.81.6-1.7-1.71.8-1.92.01.91.91.9-1.71.9
Pavlov. Cond. lever-magazine prob. diff.0.30.42.51.60.10.20.00.1-0.40.5-0.7-0.6-0.6-0.50.4-0.8
Pavlov. Cond. response bias0.71.05.82.4-1.01.2-1.0-1.10.6-0.50.30.40.40.7-0.50.2
Time in closed arm before self-admin0.00.00.0-0.20.1-0.0-0.0-0.1-0.00.10.2-0.20.10.1-0.0-0.0
Time in closed arm after self-admin0.30.30.7-0.30.6-0.50.50.4-0.60.7-0.5-0.8-0.6-0.50.6-0.6
Time in open arm before self-admin3.94.35.3-1.62.1-2.12.01.8-2.12.3-2.3-2.1-2.3-2.02.0-2.2
Time in open arm after self-admin0.10.10.2-0.10.2-0.30.30.4-0.30.3-0.4-0.2-0.3-0.20.4-0.5
Bone: periosteal estimation2.55.37.22.7-2.52.5-2.4-2.42.3-2.32.12.12.12.1-2.22.2
Bone: periosteal perimeter2.23.84.72.2-2.22.1-2.1-1.92.0-1.91.91.91.91.8-1.91.8
Bone: post-yield work0.81.21.70.7-1.11.0-1.1-1.11.2-1.11.11.31.11.1-1.11.2
Progressive ratio test 1 active lever presses1.31.63.31.8-1.61.4-1.2-0.91.1-1.31.21.31.10.7-0.91.4
Progressive ratio test 1 breakpoint1.21.53.11.7-1.61.4-1.2-0.91.1-1.31.21.31.00.6-0.91.4
Progressive ratio test 1 inactive lever presses0.00.00.20.5-0.30.2-0.10.10.0-0.10.00.00.1-0.40.10.2
Progressive ratio test 2 active lever presses0.70.81.31.1-0.91.0-1.0-0.90.9-0.70.90.70.90.6-0.90.9
Progressive ratio test 2 breakpoint0.80.91.31.1-1.01.1-1.1-0.90.9-0.70.90.80.90.6-1.00.9
Progressive ratio test 2 inactive lever presses0.40.71.00.7-0.90.9-1.0-0.80.9-0.71.00.80.90.4-1.00.9
Incentive Sensitization - Responses0.30.40.70.6-0.50.7-0.7-0.80.7-0.40.50.50.60.7-0.80.5
Incentive Sensitization - Breakpoint0.30.40.70.5-0.50.7-0.8-0.80.7-0.40.50.50.70.7-0.80.5
Sum of active levers in priming session hrs 5-63.53.35.7-1.21.7-1.71.92.0-1.81.6-1.8-1.8-1.9-2.41.9-1.6
Progressive ratio0.50.92.31.5-1.31.0-0.8-0.70.7-1.10.70.90.80.7-0.40.9
Food seeking constrained by brief footshock0.20.30.50.7-0.40.5-0.4-0.70.5-0.70.40.30.50.5-0.60.5
Seeking ratio, punishment vs. effort0.20.30.7-0.60.8-0.60.50.5-0.50.6-0.4-0.7-0.5-0.60.3-0.6
Retroperitoneal fat weight4.217.920.6-4.44.5-4.54.44.3-4.24.3-4.2-4.1-4.1-4.04.1-3.9
Reaction time number correct0.10.20.50.7-0.60.5-0.4-0.10.3-0.50.60.50.40.0-0.20.5
Reaction time mean minus median0.92.13.3-1.21.8-1.41.41.1-1.41.6-1.7-1.7-1.5-0.91.1-1.7
Reaction time mean minus median AUC1.64.05.7-1.62.4-2.01.91.9-1.92.2-2.3-2.2-2.1-1.51.6-2.2
Reaction time num false alarms1.72.43.31.6-1.51.8-1.8-1.51.7-1.31.71.51.41.3-1.81.2
Reaction time num false alarms AUC2.03.14.32.1-1.82.1-2.0-1.71.9-1.61.71.71.51.5-1.91.3
Reaction time trials correct on left0.10.20.50.7-0.60.5-0.4-0.10.3-0.50.60.50.40.0-0.20.5
Reaction time trials on left0.10.20.50.7-0.60.5-0.4-0.10.3-0.50.60.50.40.1-0.20.5
Reaction time mean1.72.64.8-2.22.2-1.81.61.1-1.51.7-1.7-1.7-1.4-0.61.1-1.8
Reaction time mean AUC2.23.56.0-2.32.5-2.11.91.3-1.81.9-2.0-1.9-1.7-0.81.4-2.1
Median of all reaction times1.21.74.0-2.01.8-1.51.30.8-1.11.3-1.2-1.3-1.0-0.30.8-1.4
Reaction time omissions1.01.52.2-1.21.5-1.21.21.2-1.11.3-1.2-1.3-1.1-0.80.9-1.5
Reaction time false alarm rate1.11.52.21.4-1.11.4-1.5-1.31.3-1.01.21.11.01.1-1.50.7
Reaction time premature initiation rate0.40.51.0-1.00.8-0.70.60.5-0.60.8-0.6-0.9-0.6-0.80.5-1.0
Reaction time premature initiations0.10.20.4-0.50.4-0.30.30.3-0.30.5-0.2-0.5-0.3-0.50.3-0.6
Std. dev. reaction times1.32.33.8-1.41.9-1.51.41.2-1.41.7-1.7-1.7-1.5-0.91.1-1.9
Reaction time trials completed0.10.20.50.7-0.60.5-0.4-0.10.3-0.50.60.50.40.1-0.20.5
Reaction time trials AUC0.30.71.01.0-1.00.9-0.7-0.50.7-0.91.00.90.80.5-0.60.9
Run reversals in cocaine runway, females0.20.20.5-0.60.2-0.40.30.7-0.20.30.4-0.0-0.1-0.60.3-0.3
Run reversals in cocaine runway, males0.20.20.5-0.40.7-0.50.4-0.1-0.40.4-0.5-0.6-0.50.10.2-0.6
Latency to leave start box in cocaine runway0.70.71.3-0.70.9-0.80.70.4-0.81.0-1.0-0.7-1.1-1.10.7-0.9
Latency to leave start box in cocaine runway, F0.40.50.9-0.40.7-0.60.50.4-0.70.9-0.9-0.6-0.9-0.90.6-0.9
Latency to leave start box in cocaine runway, M0.70.71.0-1.01.0-0.90.90.6-0.70.7-0.9-0.6-0.9-0.90.6-0.6
Std. dev. time between licks in bursts1.72.32.71.4-1.61.6-1.6-1.31.6-1.61.61.41.61.2-1.61.6
Total sessions with >9 infusions0.20.21.41.2-0.70.5-0.3-0.10.1-0.20.20.2-0.0-0.20.10.2
Short access day 1 total inactive lever presses0.91.22.7-0.70.9-0.91.01.4-1.01.1-0.8-1.0-1.1-1.61.1-1.0
Short access day 10 total inactive lever presses0.51.23.0-1.31.1-1.11.01.7-0.91.0-0.5-0.7-0.8-1.70.8-0.7
Short access day 1 total infusions0.30.41.51.2-0.70.8-0.6-0.40.5-0.60.50.30.40.3-0.40.4
Short access day 10 total infusions0.50.73.21.8-1.11.0-0.7-0.60.5-0.70.70.50.40.3-0.30.7
Short access total infusions0.10.21.81.3-0.50.4-0.2-0.10.0-0.10.2-0.1-0.1-0.10.20.1
Short access day 1 locomotion0.20.30.70.30.1-0.20.40.7-0.60.5-0.4-0.5-0.6-0.80.7-0.5
Short access day 10 total locomotion0.10.20.50.20.3-0.40.50.3-0.60.4-0.7-0.5-0.5-0.50.7-0.6
Short access total locomotion0.30.40.80.50.1-0.30.50.4-0.70.5-0.6-0.6-0.7-0.80.9-0.7
One hour access (0.3 mA shock)1.41.62.61.6-1.31.4-1.3-1.41.2-1.10.81.41.11.0-1.11.5
Compulsive drug intake8.39.911.3-3.23.2-3.33.32.8-3.33.4-3.3-3.2-3.0-2.53.2-3.1
One hour access (shock baseline)4.67.19.13.0-2.72.8-2.7-2.62.7-2.72.42.72.52.2-2.62.7
Social response proportion0.91.12.4-0.61.3-1.01.10.6-1.01.0-1.0-1.5-0.9-0.60.9-1.4
Social responses1.72.13.31.5-1.31.6-1.6-1.81.5-1.31.21.11.51.6-1.61.3
Social time0.50.71.1-1.01.0-0.80.70.7-0.81.0-0.9-0.9-0.8-0.60.6-0.7
Soleus weight0.00.00.10.1-0.2-0.00.00.40.0-0.00.20.20.0-0.40.10.2
Bone: stiffness5.69.111.22.9-3.13.1-3.1-3.33.0-3.02.92.93.03.3-2.92.8
Tibialis anterior weight0.20.81.1-0.40.7-0.90.91.0-1.00.9-0.8-0.9-0.9-1.01.0-0.9
Time to tail flick, vehicle, before self-admin2.42.53.2-1.21.5-1.61.61.5-1.61.7-1.2-1.7-1.6-1.81.7-1.5
Time to tail flick, vehicle, after self-admin3.24.25.6-2.42.3-2.32.22.1-2.12.0-1.7-2.1-1.9-1.32.0-2.0
Time to tail flick, test, before self-admin0.10.10.8-0.90.4-0.30.20.1-0.10.0-0.40.00.0-0.1-0.1-0.0
Time to tail flick, test, after self-admin0.30.31.5-0.80.3-0.50.51.2-0.40.4-0.5-0.2-0.4-0.90.4-0.1
Delta time to tail flick, vehicle, before/after SA0.80.72.30.1-0.50.6-0.7-0.70.8-1.00.90.90.91.5-0.90.8
Delta time to tail flick, test, before/after SA0.80.91.6-0.50.7-0.80.81.3-0.91.0-0.9-0.9-1.1-1.20.9-0.8
Tibia length6.919.124.85.0-4.54.7-4.6-4.94.2-4.33.84.04.04.4-4.14.0
Ambulatory time before self-admin2.13.15.12.1-2.22.0-1.8-1.21.7-1.81.91.81.61.0-1.51.8
Ambulatory time after self-admin1.11.32.11.4-1.41.3-1.2-1.11.1-1.11.20.91.10.9-1.01.0
Bone: tissue strength0.60.60.80.5-0.70.8-0.8-0.80.8-0.70.80.80.80.7-0.90.7
Total heroin consumption2.02.43.7-0.71.2-1.41.61.8-1.61.4-1.5-1.5-1.6-1.91.8-1.5
Bone: trabecular number0.30.52.70.2-0.30.4-0.4-1.40.4-0.50.40.20.71.6-0.50.1
Bone: trabecular spacing0.40.61.9-0.20.5-0.50.61.2-0.70.6-0.6-0.7-0.8-1.40.7-0.5
Bone: trabecular thickness1.31.72.81.1-1.21.3-1.3-1.61.2-1.31.21.21.21.7-1.31.1
Bone: trabecular tissue density0.60.81.41.1-0.91.0-1.0-1.20.8-0.70.70.80.81.1-0.90.8
Water consumed over 24 hours0.40.63.11.7-1.00.9-0.7-0.60.5-0.70.50.50.50.2-0.30.4
Number of responses in last shaping day1.21.31.61.2-1.21.2-1.1-0.91.2-1.21.21.21.21.0-1.11.0