Hub : Genes

LOC108349515

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability LOC108349515 0.08 0.06 2.3e-12 0.06 0.08 0.09 0.08 2.7e-09 4.0e-12 5.1e-13 2.5e-12
2 NAcc gene expression LOC108349515 0.15 0.12 6.6e-14 0.09 0.09 0.09 0.09 2.1e-13 2.4e-13 1.1e-13 1.2e-13
3 BLA mRNA stability LOC108349515 0.1 0.07 1.0e-04 0.06 0.06 0.05 0.06 6.0e-04 3.8e-04 9.4e-04 3.0e-04
4 Brain mRNA stability LOC108349515 0.03 0.02 2.0e-03 0.04 0.03 0.03 0.04 4.3e-05 8.7e-04 3.8e-04 1.5e-04
5 PL mRNA stability LOC108349515 0.07 0.05 2.7e-08 0.07 0.06 0.06 0.06 4.9e-08 4.5e-07 1.0e-06 1.0e-06
6 PL gene expression LOC108349515 0.07 0.07 9.9e-05 0.03 0.04 0.05 0.04 1.1e-04 4.2e-05 8.5e-06 2.8e-05
7 BLA gene expression LOC108349515 0.13 0.09 6.0e-04 0.01 0.04 0.04 0.04 8.2e-02 2.0e-03 2.9e-03 2.7e-03
8 IC gene expression LOC108349515 0.15 0.11 7.1e-03 0.02 0.04 0.08 0.04 3.7e-02 9.0e-03 2.4e-04 8.1e-03
9 pVTA gene expression LOC108349515 0.1 0.07 1.4e-03 0.03 0.02 0.02 0.03 2.8e-03 4.8e-03 9.5e-03 3.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.10.2-0.1-0.10.4-0.2-0.4-0.10.1-0.30.2
Area under the delay curve0.30.51.00.70.9-0.71.00.60.9-0.50.10.3
BMI with tail0.41.43.31.81.2-1.51.21.41.0-0.60.90.1
BMI without tail0.10.40.8-0.8-0.60.5-0.6-0.1-0.70.9-0.3-0.8
Body weight1.35.58.1-2.8-2.92.0-2.5-1.8-2.62.7-1.5-2.0
Weight adjusted by age0.10.41.7-0.10.00.7-0.5-1.3-0.20.0-0.60.4
Bone surface2.55.07.1-2.5-2.72.4-2.6-2.1-2.42.1-1.9-1.2
Bone volume1.83.75.0-2.2-2.22.1-2.1-1.9-2.01.7-1.7-0.9
Breakpoint value in progressive ratio session0.20.31.4-0.40.0-0.8-0.10.60.1-0.51.20.3
Number of licking bursts0.00.10.20.10.2-0.30.10.20.1-0.20.40.1
Context. condit. distance diff. score0.20.20.50.50.4-0.5-0.0-0.00.3-0.70.70.7
Locomotion velocity, session 12.42.86.91.81.6-0.10.9-1.01.8-2.31.52.6
Locomotion distance, session 11.21.55.0-1.2-0.91.7-1.5-2.2-0.6-0.20.11.1
Locomotion velocity, session 20.91.12.61.01.1-0.30.6-0.31.2-1.50.91.6
Locomotion distance, session 20.81.23.6-1.1-0.91.8-0.9-1.9-0.50.3-0.60.5
Locomotion velocity, session 30.10.10.4-0.20.2-0.20.1-0.00.4-0.50.20.6
Locomotion distance, session 30.20.20.6-0.4-0.20.4-0.5-0.7-0.0-0.40.20.8
Stereotopy head waving bouts, day 30.20.21.30.30.1-0.5-0.30.5-0.3-0.01.1-0.2
Stereotopy head waving duration, day 30.10.20.60.30.2-0.5-0.20.5-0.30.10.7-0.4
Locomotion velocity, session 70.10.20.5-0.10.00.1-0.4-0.50.0-0.50.50.7
Locomotion distance, session 70.30.41.10.80.7-0.20.3-0.50.7-0.80.41.0
Stereotopy head waving bouts, day 70.60.71.5-1.1-1.00.4-1.2-0.1-1.20.70.4-0.7
Stereotopy head waving duration, day 70.50.61.2-0.9-0.90.3-1.1-0.1-1.10.70.1-0.7
Locomotion velocity, session 80.50.62.00.20.3-0.1-0.2-0.50.5-1.21.21.4
Locomotion distance, session 80.20.30.9-0.00.10.4-0.3-0.90.2-0.60.41.0
Degree of sensitization distance0.00.00.10.30.1-0.1-0.1-0.1-0.0-0.10.20.1
Degree of sensitization stereotypy0.30.30.7-0.8-0.70.2-0.70.1-0.80.60.1-0.6
Conditioned locomotion0.20.20.90.40.1-0.1-0.5-0.50.1-0.60.60.9
Cocaine response after cond. corrected0.81.23.51.00.7-1.21.51.90.80.2-0.9-0.8
Cocaine response after cond. not corrected0.40.62.3-0.3-0.50.50.20.3-0.41.1-1.5-1.1
Cocaine response before conditioning4.65.510.1-2.5-2.53.2-2.8-3.1-2.31.7-1.1-0.6
Saline control response0.50.62.80.20.1-0.3-0.6-0.70.3-1.10.71.7
Bone: connectivity density0.10.10.30.50.2-0.20.30.20.3-0.1-0.40.2
Bone: cortical apparent density0.61.01.81.31.00.11.1-0.61.3-0.7-1.11.1
Bone: cortical area0.91.42.4-1.5-1.41.0-1.6-1.0-1.41.0-0.4-0.7
Bone: cortical porosity0.30.31.0-0.4-0.2-0.7-0.41.0-0.3-0.21.0-0.1
Bone: cortical porosity0.60.61.4-1.2-0.9-0.2-1.00.7-1.00.40.7-0.6
Bone: cortical thickness0.40.71.30.90.9-0.90.40.50.7-1.01.10.8
Bone: cortical thickness0.20.30.60.80.50.30.4-0.60.5-0.3-0.50.5
Bone: cortical tissue density0.60.91.61.31.00.11.1-0.61.3-0.7-1.11.1
Condit. Reinf. active minus inactive responses0.10.10.5-0.7-0.1-0.5-0.10.5-0.0-0.20.30.1
Condit. Reinf. active-inactive response ratio0.80.82.20.50.9-1.51.01.40.8-0.70.40.2
Condit. Reinf. active responses0.40.51.3-1.1-0.90.5-1.0-0.3-0.80.30.2-0.1
Condit. Reinf. inactive responses2.22.95.1-1.8-2.02.2-2.3-2.1-1.81.0-0.1-0.3
Incentive salience index mean0.20.21.1-1.0-0.50.3-0.4-0.2-0.30.2-0.2-0.0
Condit. Reinf. lever presses0.40.61.1-0.9-0.61.0-0.4-1.0-0.40.6-0.9-0.2
Condit. Reinf. active minus inactive responses2.74.16.8-2.6-2.42.1-2.6-2.2-2.31.6-0.4-0.9
Condit. Reinf. active-inactive response ratio3.75.88.3-2.9-2.72.6-2.6-2.2-2.62.4-1.7-1.7
Condit. Reinf. active responses2.53.57.0-2.4-2.21.9-2.7-2.2-2.10.90.5-0.3
Condit. Reinf. inactive responses0.40.63.2-0.7-0.5-0.0-0.9-0.4-0.5-0.61.80.6
Condit. Reinf. lever presses1.92.76.0-2.5-2.10.9-1.8-0.3-2.11.60.1-1.6
Condit. Reinf. lever reinforcers received3.24.58.6-2.7-2.42.2-2.9-2.5-2.31.10.2-0.4
Conditioned reinforcement - actives0.20.83.71.20.30.60.6-0.10.20.9-1.9-0.8
Conditioned reinforcement - inactives0.51.43.7-0.3-0.51.9-0.5-1.8-0.51.2-1.9-0.5
Conditioned locomotion0.20.31.30.5-0.20.40.1-0.0-0.10.7-1.1-0.6
Patch foraging indifference point 0 sec0.51.32.71.71.5-0.80.90.31.3-1.30.61.3
Patch foraging indifference point AUC0.20.60.90.91.0-0.80.80.90.7-0.60.40.3
Delay disc. indifference point, 0s delay0.80.92.21.51.4-0.30.5-0.60.8-1.10.31.1
Delay disc. indifference point, 16s delay0.40.52.3-1.0-0.5-0.60.31.5-0.10.50.3-0.8
Delay disc. indifference point, 2s delay1.61.83.81.91.8-0.91.90.41.8-1.0-0.10.8
Delay disc. indifference point, 24s delay0.20.31.4-0.40.1-0.70.51.20.3-0.00.4-0.3
Delay disc. indifference point, 4s delay0.10.10.4-0.2-0.10.30.3-0.10.10.4-0.7-0.3
Delay disc. indifference point, 8s delay0.10.20.50.70.7-0.30.60.20.6-0.40.00.3
Indifference point function ln k1.54.49.0-2.2-2.22.6-2.7-3.0-2.11.3-0.6-0.2
Indifference point function log k1.54.49.0-2.2-2.22.6-2.7-3.0-2.11.3-0.6-0.2
Patch foraging total patch changes 0 sec0.41.22.31.51.4-0.80.90.31.2-1.30.71.3
Patch foraging total patch changes 12 sec0.30.31.31.10.7-0.40.60.70.4-0.2-0.40.1
Patch foraging total patch changes 18 sec0.30.71.11.00.9-1.01.00.71.0-0.80.20.6
Patch foraging total patch changes 24 sec0.10.51.3-1.1-0.60.3-0.20.4-0.50.8-0.9-0.8
Patch foraging total patch changes 6 sec0.71.12.11.41.3-1.11.21.11.1-0.90.30.5
Patch foraging time to switch 0 sec0.62.39.4-0.3-0.1-1.61.63.10.31.0-0.9-2.1
Patch foraging water rate 0 sec0.20.62.30.30.10.8-0.8-1.5-0.1-0.60.41.1
Patch foraging water rate 12 sec0.41.66.5-0.8-0.61.6-1.5-2.6-0.7-0.20.01.0
Patch foraging water rate 18 sec0.30.72.7-0.1-0.31.0-1.1-1.6-0.5-0.30.60.8
Patch foraging water rate 24 sec0.40.52.1-0.2-0.51.0-1.0-1.4-0.5-0.0-0.10.5
Patch foraging water rate 6 sec5.17.515.7-4.0-3.43.0-2.9-2.7-2.72.2-1.4-1.2
Seeking ratio, delayed vs. immediate footshock0.50.81.71.20.8-0.1-0.4-0.90.3-1.10.81.3
Distance traveled before self-admin0.61.36.50.30.31.0-1.1-2.5-0.2-0.80.21.5
Distance traveled after self-admin0.91.74.91.01.1-0.9-0.5-0.40.4-1.82.21.8
Extensor digitorum longus weight0.31.42.2-1.3-1.40.7-1.1-0.5-1.41.5-0.8-1.3
Bone: elastic displacement0.60.84.00.30.7-0.8-0.20.30.2-1.12.00.9
Bone: elastic work0.20.20.9-0.2-0.10.5-0.5-1.0-0.30.10.40.2
Bone: endosteal estimation2.45.97.6-2.7-2.82.5-2.3-2.1-2.52.7-2.3-1.9
Bone: endosteal perimeter1.53.75.3-2.3-2.21.9-2.1-1.7-2.12.0-1.4-1.3
Epididymis fat weight0.31.53.9-2.0-1.10.0-0.30.7-1.01.5-0.7-1.9
Delta time in closed arm before/after self-admin1.00.94.32.11.20.01.00.30.8-0.3-0.90.1
Delta time in open arm before/after self-admin1.31.54.3-1.1-1.41.1-2.1-1.6-1.50.40.20.1
Diff in mean of infusions in LGA sessions0.20.40.91.00.8-0.00.6-0.60.8-0.70.10.8
Delay discount exponential model param0.20.30.8-0.5-0.70.5-0.9-0.5-0.70.3-0.0-0.2
Extinction: sum of active levers before priming0.20.31.3-0.50.2-0.4-0.3-0.20.0-0.71.20.6
Active lever presses in extinction session 60.80.81.6-1.1-1.3-0.1-0.31.0-0.81.1-0.2-1.2
Bone: final force1.32.23.8-1.2-1.41.9-1.0-1.8-1.11.6-2.0-0.9
Bone: final moment1.62.54.4-1.3-1.52.1-1.1-2.1-1.21.6-2.0-0.8
Food consumed during 24 hour testing period0.81.62.7-1.2-1.31.6-1.3-1.5-1.21.2-1.1-0.6
Glucose1.93.04.72.22.0-1.71.71.11.9-1.91.41.4
Heart weight1.62.63.7-1.8-1.91.7-1.6-1.0-1.81.8-1.5-1.3
Delay discount hyperbolic model param0.40.51.2-0.7-0.90.6-1.1-0.5-0.90.5-0.0-0.3
Intermittent access intake day 1-15 change0.10.71.2-1.1-1.10.9-0.8-1.0-0.70.9-0.5-0.5
Intermittent access intake escalation0.31.63.7-1.9-1.71.1-1.1-1.1-1.11.3-0.7-0.9
Intermittent access intake escalation 20.20.30.6-0.8-0.30.1-0.4-0.8-0.1-0.30.70.5
Intermitt. access day 1 inactive lever presses0.22.35.0-2.2-1.81.6-1.3-1.0-1.41.7-1.2-1.3
Intermitt. access day 15 inactive lever presses0.63.45.3-0.7-1.62.3-1.9-1.3-2.02.2-2.3-1.6
Intermitt. access escalation Index0.30.94.02.01.0-1.00.80.60.9-0.50.30.2
Intermittent access day 1 total infusions0.20.61.90.0-0.60.8-0.1-0.4-0.31.1-1.4-0.9
Intermittent access day 15 total infusions0.51.32.4-1.2-1.51.0-0.4-0.7-0.71.6-1.3-1.3
Intermittent access terminal intake (last 3 days)0.61.01.8-1.3-1.30.9-0.1-0.8-0.51.3-1.1-1.0
Intermittent access total infusions1.11.33.5-0.6-1.11.3-0.2-1.0-0.51.5-1.9-1.1
Intermittent access day 1 locomotion0.50.92.7-0.5-0.81.2-0.1-1.0-0.31.3-1.6-0.9
Intermittent access day 15 total locomotion0.10.63.0-0.5-0.51.0-0.2-1.70.00.5-0.50.1
Intermittent access total locomotion1.61.93.6-1.2-1.41.7-0.7-1.9-0.81.6-1.7-0.9
Intermittent access standard deviation0.10.30.80.30.2-0.90.80.30.8-0.60.60.4
Left kidney weight2.721.931.2-5.5-5.65.0-5.3-4.6-5.14.4-2.9-2.6
Right kidney weight3.424.034.7-5.9-5.85.3-5.4-4.0-5.54.9-3.3-3.3
Cocaine induced anxiety0.51.53.6-1.4-1.41.1-1.9-1.0-1.60.9-0.1-0.4
Post-drug Anxiety1.82.15.5-2.3-2.10.8-1.8-0.3-1.81.10.2-0.9
Baseline Anxiety0.30.41.1-0.10.3-0.91.01.00.8-0.40.5-0.0
Tail length2.211.920.8-4.6-4.03.7-3.8-3.2-3.63.1-2.3-1.8
Length with tail3.214.324.5-5.0-4.63.6-3.9-3.0-4.13.9-2.6-2.7
Length without tail1.37.011.9-2.8-3.52.0-2.4-1.2-2.93.2-2.3-2.7
Times rat made contact with spout0.10.10.20.40.1-0.20.10.5-0.10.2-0.1-0.5
Lifetime Intake0.81.03.70.2-0.61.10.1-0.8-0.31.3-1.9-1.0
Liver weight, left0.91.62.1-1.2-1.41.4-1.4-1.1-1.51.3-1.0-0.9
Liver weight, right0.00.00.10.00.00.1-0.10.1-0.20.20.2-0.4
Locomotor activity0.10.10.30.10.1-0.30.30.50.10.10.2-0.4
Locomotor testing distance0.20.41.0-0.3-0.50.2-0.20.4-0.61.0-0.9-1.0
Locomotor testing rearing0.31.02.1-0.6-1.01.0-1.0-0.6-1.11.2-1.5-0.8
Locomotion in novel chamber1.31.83.21.81.1-1.61.41.11.5-1.21.20.9
Locomotion in novel chamber post-restriction0.51.43.31.81.5-0.91.61.11.3-0.4-0.50.0
Fecal boli incidents, locomotor time 10.10.20.5-0.3-0.20.6-0.1-0.7-0.10.3-0.5-0.0
Change in fecal boli incidents, locomotor task3.33.56.62.62.3-1.92.21.42.1-1.70.91.1
Time >=10cm from walls, locomotor time 10.00.00.10.2-0.1-0.10.20.30.10.1-0.3-0.2
Bouts of movement, locomotor time 10.60.82.31.10.80.3-0.3-1.50.3-1.00.41.3
Total resting periods, locomotor time 10.50.61.21.11.0-0.10.2-0.80.6-1.00.51.1
Rest time, locomotor task time 10.71.11.9-1.3-1.11.4-0.6-1.2-0.81.1-1.3-0.6
Distance moved, locomotor task time 10.41.22.80.81.1-1.40.51.20.7-1.21.70.7
Vertical activity count, locomotor time 10.74.67.52.72.7-2.21.51.11.9-2.52.31.9
Time >=10cm from walls, locomotor time 20.20.51.20.70.6-0.90.91.10.7-0.50.40.1
Bouts of movement, locomotor time 20.00.00.1-0.1-0.20.2-0.0-0.1-0.10.1-0.2-0.1
Total resting periods, locomotor time 20.00.00.10.20.10.20.2-0.20.10.0-0.30.1
Rest time, locomotor task time 20.20.30.80.90.70.00.3-0.50.5-0.5-0.10.6
Distance moved, locomotor task time 20.10.10.60.00.1-0.5-0.10.40.0-0.40.80.2
Vertical activity count, locomotor time 20.10.30.60.70.8-0.60.40.30.5-0.60.70.5
Light reinforcement 10.41.63.71.91.4-0.40.5-0.61.2-1.60.31.9
Light reinforcement 21.32.84.72.22.0-1.81.60.91.9-1.80.91.6
Bone: marrow area2.56.17.7-2.7-2.82.5-2.3-2.1-2.62.8-2.3-2.0
Bone: maximum diameter1.42.84.2-2.0-2.01.3-1.8-0.9-2.01.8-1.1-1.5
Bone: maximum force2.24.35.3-2.1-2.22.3-1.8-2.1-2.02.3-2.2-1.5
Bone: maximum moment2.44.56.0-2.1-2.22.4-1.9-2.3-2.02.2-2.2-1.4
Mean time between licks in bursts0.21.52.21.31.4-1.01.00.41.3-1.51.51.3
Mean num. licks in bursts0.10.30.9-0.1-0.30.4-0.1-0.1-0.40.8-0.9-0.7
Cd content in liver1.41.52.6-0.8-1.41.6-1.5-1.6-1.31.0-1.1-0.3
Co content in liver0.70.82.31.30.60.60.2-1.50.6-0.5-0.81.1
Cu content in liver0.70.82.0-0.2-1.01.0-0.8-0.9-0.80.9-1.4-0.4
Fe content in liver0.20.20.4-0.1-0.50.5-0.5-0.5-0.50.5-0.7-0.2
K content in liver0.00.00.10.0-0.30.1-0.40.0-0.2-0.0-0.10.2
Mg content in liver0.10.10.40.0-0.4-0.2-0.10.6-0.30.4-0.5-0.4
Mn content in liver0.50.51.4-1.2-0.9-0.1-1.00.4-0.90.50.1-0.5
Na content in liver1.82.03.51.41.4-1.91.01.71.2-1.51.41.0
Rb content in liver3.44.06.7-2.5-2.62.0-2.3-1.3-2.31.9-1.1-1.3
Se content in liver0.91.03.60.90.6-1.80.71.90.4-0.40.8-0.2
Sr content in liver9.68.418.84.33.9-2.62.71.33.0-3.01.62.2
Zn content in liver0.40.41.50.5-0.2-0.40.71.20.20.5-0.8-0.8
Bone: minimum diameter3.05.89.5-3.1-2.92.6-2.8-2.3-2.62.1-1.3-1.2
Time in familiar zone, hab. session 11.11.25.3-0.0-0.31.5-0.7-2.3-0.30.4-1.30.5
Time in novel zone, hab. session 11.21.43.40.70.8-1.60.71.80.7-1.11.90.3
Total zone transitions, hab. session 10.71.03.4-0.00.10.9-0.3-1.70.6-1.10.61.8
Total locomotion distance, hab. session 10.50.72.60.40.50.40.1-1.10.7-1.10.61.6
Locomotion velocity, hab. session 10.40.51.80.20.30.40.1-0.90.6-0.90.51.3
Time in familiar zone, hab. session 23.33.85.6-2.0-2.11.9-1.5-1.2-1.92.3-2.4-1.8
Time in novel zone, hab. session 21.82.03.81.41.5-1.61.01.11.3-1.61.91.1
Total zone transitions, hab. session 21.51.94.1-1.7-1.41.8-1.8-2.0-1.10.30.00.6
Total locomotion distance, hab. session 20.30.41.40.20.30.20.0-0.60.5-0.90.71.2
Locomotion velocity, hab. session 20.40.61.90.30.50.00.1-0.60.7-1.10.91.4
Novel to familiar place preference ratio0.10.10.3-0.4-0.40.1-0.40.0-0.50.40.0-0.4
Novelty place preference0.20.20.4-0.6-0.50.3-0.6-0.2-0.60.5-0.1-0.4
Time in novel zone, NPP test0.20.30.5-0.6-0.60.4-0.6-0.3-0.70.6-0.3-0.5
Total zone transitions, NPP test0.20.30.9-0.4-0.30.8-0.2-0.90.1-0.30.00.7
Total locomotion distance, NPP test0.30.41.1-1.0-0.80.9-0.7-0.7-0.60.3-0.1-0.1
Locomotion velocity, NPP test0.30.40.9-1.0-0.70.9-0.8-0.8-0.50.10.20.3
Intraocular pressure0.10.20.3-0.60.3-0.30.30.00.4-0.50.30.5
Delta distance traveled before/after self-admin1.11.22.70.60.9-1.60.71.70.7-1.01.60.4
Delta ambulatory time before/after self-admin0.71.11.81.21.2-1.30.91.40.9-1.01.10.5
Parametrial fat weight1.43.27.22.72.0-2.01.92.01.7-1.21.10.3
Pavlov. Cond. lever latency0.10.20.30.50.5-0.50.20.20.4-0.50.30.5
Pavlov. Cond. magazine entry latency0.30.41.40.50.5-0.70.91.20.6-0.20.5-0.3
Pavlov. Cond. change in total contacts0.30.30.60.70.6-0.50.70.50.7-0.40.20.3
Pavlov. Cond. index score0.20.20.60.50.5-0.40.80.60.6-0.30.30.0
Pavlov. Cond. latency score0.10.20.50.40.4-0.30.70.60.5-0.10.2-0.1
Pavlov. Cond. lever contacts0.40.50.9-0.8-0.80.5-0.40.0-0.70.9-0.4-0.9
Pavlov. Cond. magazine entry number0.10.10.5-0.2-0.20.4-0.6-0.7-0.30.0-0.10.3
Pavlov. Cond. intertrial magazine entries1.01.23.21.00.8-0.3-0.2-0.60.6-1.51.61.8
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.50.4-0.50.70.70.5-0.30.3-0.0
Pavlov. Cond. response bias0.20.20.7-0.4-0.40.10.20.5-0.20.6-0.4-0.8
Pavlov. Cond. lever latency0.40.53.4-0.1-0.20.80.2-0.60.00.5-1.8-0.2
Pavlov. Cond. magazine entry latency0.40.51.20.70.7-1.10.41.10.3-0.41.1-0.1
Pavlov. Cond. change in total contacts0.20.62.2-0.6-0.4-0.0-1.2-0.5-0.7-0.11.50.4
Pavlov. Cond. index score0.20.31.6-0.2-0.1-0.4-0.50.3-0.4-0.01.3-0.1
Pavlov. Cond. latency score0.20.42.10.10.3-0.8-0.10.7-0.1-0.31.50.0
Pavlov. Cond. lever contacts0.30.42.6-0.2-0.1-0.5-0.50.3-0.4-0.21.60.0
Pavlov. Cond. magazine entry number0.30.40.8-0.8-0.70.9-0.5-0.8-0.40.4-0.8-0.1
Pavlov. Cond. intertrial magazine entries1.73.86.1-2.5-2.42.3-2.1-2.1-1.91.5-1.2-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.90.10.2-0.5-0.30.4-0.2-0.21.40.1
Pavlov. Cond. response bias0.40.51.4-0.8-0.60.2-1.0-0.2-0.90.31.2-0.3
Time in closed arm before self-admin0.61.02.1-1.5-1.30.9-1.2-0.9-1.10.8-0.4-0.5
Time in closed arm after self-admin0.30.31.20.1-0.30.50.10.2-0.20.7-1.1-0.8
Time in open arm before self-admin2.42.97.62.82.3-1.42.11.51.8-1.20.20.7
Time in open arm after self-admin0.40.51.00.80.6-0.6-0.1-0.00.3-0.81.00.9
Bone: periosteal estimation1.94.46.0-2.5-2.42.1-2.3-1.9-2.32.2-1.6-1.5
Bone: periosteal perimeter1.42.74.1-1.9-1.91.6-2.0-1.6-1.91.5-0.9-0.9
Bone: post-yield work3.45.99.0-2.7-3.02.2-2.4-1.5-2.62.7-2.5-2.0
Progressive ratio test 1 active lever presses0.20.41.40.90.40.8-0.0-1.20.20.1-0.90.3
Progressive ratio test 1 breakpoint0.20.41.40.80.40.80.0-1.20.20.1-0.90.3
Progressive ratio test 1 inactive lever presses0.71.94.7-0.1-0.72.1-0.8-1.9-0.81.3-2.2-0.7
Progressive ratio test 2 active lever presses0.50.81.7-0.6-1.10.8-0.2-0.3-0.51.3-1.2-1.1
Progressive ratio test 2 breakpoint0.81.02.0-0.7-1.20.9-0.3-0.4-0.71.4-1.2-1.2
Progressive ratio test 2 inactive lever presses0.82.64.9-0.7-1.52.2-1.3-1.9-1.31.8-2.0-1.0
Incentive Sensitization - Responses1.23.26.7-2.4-2.61.4-1.4-0.6-1.72.1-1.1-1.8
Incentive Sensitization - Breakpoint1.22.65.8-2.2-2.41.1-1.2-0.4-1.62.0-0.9-1.8
Sum of active levers in priming session hrs 5-60.40.31.2-0.40.1-0.3-0.6-0.3-0.1-0.61.10.7
Progressive ratio0.10.20.40.20.20.2-0.6-0.5-0.2-0.60.60.6
Food seeking constrained by brief footshock4.04.910.23.02.9-0.10.2-2.11.4-2.91.33.2
Seeking ratio, punishment vs. effort0.10.21.20.10.10.5-0.2-1.10.1-0.2-0.20.5
Retroperitoneal fat weight2.29.921.13.33.3-4.24.04.63.0-1.61.5-0.2
Reaction time number correct0.10.41.21.10.5-0.60.30.20.5-0.60.90.4
Reaction time mean minus median0.00.00.00.10.10.1-0.0-0.10.00.10.00.1
Reaction time mean minus median AUC0.00.00.10.40.0-0.00.10.2-0.00.2-0.3-0.2
Reaction time num false alarms0.10.10.60.80.2-0.20.10.00.2-0.10.00.2
Reaction time num false alarms AUC0.41.03.51.91.1-0.70.70.11.0-1.00.51.1
Reaction time trials correct on left0.10.41.21.10.5-0.60.30.20.5-0.60.90.4
Reaction time trials on left0.10.41.21.10.5-0.60.40.20.5-0.70.90.4
Reaction time mean0.61.22.1-1.4-1.21.1-1.0-0.6-1.11.3-1.2-0.9
Reaction time mean AUC0.30.71.2-1.0-0.90.7-0.6-0.1-0.81.1-1.1-0.9
Median of all reaction times0.91.32.5-1.6-1.21.1-0.9-0.5-1.11.3-1.3-1.0
Reaction time omissions0.40.61.51.20.8-0.40.4-0.30.8-0.90.21.1
Reaction time false alarm rate0.30.41.31.10.8-0.40.4-0.10.7-0.60.10.8
Reaction time premature initiation rate0.10.20.7-0.8-0.40.3-0.10.0-0.20.5-0.8-0.4
Reaction time premature initiations0.00.10.1-0.3-0.2-0.10.20.3-0.00.2-0.3-0.3
Std. dev. reaction times0.20.81.1-1.0-1.00.9-0.8-0.5-0.91.1-0.9-0.7
Reaction time trials completed0.10.41.21.10.5-0.60.40.20.5-0.70.90.4
Reaction time trials AUC0.10.20.60.80.3-0.50.30.20.3-0.40.70.2
Run reversals in cocaine runway, females0.70.71.4-0.9-0.90.8-0.7-0.1-0.91.0-1.2-0.9
Run reversals in cocaine runway, males0.10.10.60.20.4-0.00.50.00.40.2-0.7-0.2
Latency to leave start box in cocaine runway0.30.50.8-0.9-0.80.8-0.5-0.8-0.60.6-0.7-0.3
Latency to leave start box in cocaine runway, F0.10.10.5-0.2-0.00.30.0-0.3-0.00.2-0.7-0.1
Latency to leave start box in cocaine runway, M1.41.32.6-1.6-1.61.1-1.1-1.1-1.11.0-0.5-0.7
Std. dev. time between licks in bursts1.01.94.61.11.2-0.50.3-0.51.1-1.92.12.1
Total sessions with >9 infusions0.60.72.11.30.31.0-0.2-1.2-0.10.5-1.4-0.1
Short access day 1 total inactive lever presses0.71.42.4-1.4-1.41.0-0.5-0.3-0.81.5-1.4-1.3
Short access day 10 total inactive lever presses0.10.41.9-1.4-0.80.4-0.1-0.4-0.30.5-0.3-0.4
Short access day 1 total infusions0.20.51.61.30.90.10.8-0.10.7-0.0-0.80.1
Short access day 10 total infusions0.30.52.21.50.9-0.10.9-0.00.8-0.2-0.60.2
Short access total infusions0.81.14.02.01.3-0.21.30.21.1-0.2-1.00.1
Short access day 1 locomotion0.40.63.10.70.20.70.3-0.30.00.9-1.8-0.7
Short access day 10 total locomotion0.10.52.50.40.40.7-0.1-1.60.3-0.3-0.30.7
Short access total locomotion0.81.24.22.01.50.20.7-1.21.1-0.7-0.61.0
One hour access (0.3 mA shock)2.93.45.0-1.4-2.22.2-1.7-1.9-1.72.1-1.9-1.4
Compulsive drug intake1.72.54.8-2.2-2.11.4-2.0-1.4-1.71.3-0.0-0.8
One hour access (shock baseline)0.30.83.60.4-0.40.80.3-0.1-0.21.2-1.9-1.1
Social response proportion1.62.05.3-2.3-1.81.2-1.0-0.4-1.31.5-1.1-1.3
Social responses3.03.97.5-2.7-2.42.2-2.0-1.6-2.01.8-1.4-1.1
Social time1.52.46.5-1.1-1.42.3-2.0-2.5-1.40.5-0.50.3
Soleus weight0.10.20.4-0.4-0.50.1-0.4-0.2-0.40.5-0.6-0.3
Bone: stiffness1.83.34.4-1.5-2.02.1-1.7-1.9-1.81.9-2.1-1.2
Tibialis anterior weight0.41.44.00.90.9-1.91.32.00.7-0.00.6-0.8
Time to tail flick, vehicle, before self-admin0.20.21.10.10.10.5-0.6-1.1-0.2-0.2-0.00.5
Time to tail flick, vehicle, after self-admin0.71.57.2-2.7-1.50.6-0.4-0.2-0.71.1-0.5-1.0
Time to tail flick, test, before self-admin1.21.42.21.11.4-0.71.1-0.61.5-1.40.71.5
Time to tail flick, test, after self-admin0.20.21.11.00.5-0.3-0.00.7-0.0-0.1-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.70.83.0-1.7-0.9-0.30.90.80.30.7-0.4-1.0
Delta time to tail flick, test, before/after SA0.70.81.8-0.1-0.80.7-1.20.4-1.31.1-0.8-1.1
Tibia length3.710.315.4-3.9-3.73.5-3.5-2.6-3.63.2-2.1-2.2
Ambulatory time before self-admin0.41.14.9-0.0-0.11.0-1.4-2.2-0.6-0.50.21.1
Ambulatory time after self-admin0.81.22.51.10.7-0.2-1.1-1.0-0.2-1.41.61.6
Bone: tissue strength0.50.51.11.00.70.20.4-0.90.7-0.7-0.11.0
Total heroin consumption0.20.20.8-0.40.0-0.3-0.5-0.2-0.2-0.40.90.4
Bone: trabecular number0.20.40.80.90.8-0.40.70.30.8-0.60.20.6
Bone: trabecular spacing0.10.10.3-0.5-0.30.0-0.00.2-0.20.30.2-0.5
Bone: trabecular thickness0.00.10.4-0.00.00.00.0-0.10.00.1-0.70.0
Bone: trabecular tissue density0.20.31.70.20.2-0.80.41.30.1-0.00.0-0.4
Water consumed over 24 hours0.20.41.7-0.2-0.41.1-0.6-1.3-0.40.3-0.60.2
Number of responses in last shaping day0.40.62.41.00.70.30.70.30.30.5-1.6-0.5