Hub : Genes

LOC108348302

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XM_063275932.1 0.04 0.02 1.4e-03 0.03 0 0 0.01 6.0e-04 1.5e-01 1.1e-01 3.5e-02
2 PL gene expression LOC108348302 0.31 0.14 0.0e+00 0.13 0.14 0.15 0.15 1.1e-13 1.3e-15 2.1e-16 1.9e-16
3 NAcc gene expression LOC108348302 0.13 0.07 7.0e-15 0.09 0.1 0.09 0.1 2.1e-13 6.4e-15 5.0e-14 3.1e-15
4 Adipose gene expression LOC108348302 0.17 0.08 4.9e-14 0.1 0.11 0.1 0.11 8.2e-11 8.2e-12 1.1e-11 5.3e-12
5 Brain gene expression LOC108348302 0.17 0.07 5.2e-13 0.11 0.14 0.14 0.13 9.3e-11 7.5e-13 1.5e-12 3.1e-12
6 pVTA gene expression LOC108348302 0.07 0.05 4.6e-04 0.04 0.03 0.04 0.04 4.7e-04 1.0e-03 2.3e-04 3.2e-04
7 IC gene expression LOC108348302 0.11 0.07 6.6e-03 0.05 0.04 0.08 0.05 4.5e-03 7.1e-03 3.5e-04 3.6e-03
8 Adipose mRNA stability LOC108348302 0.13 0.08 7.9e-04 0 0.03 0.01 0.01 9.9e-02 1.3e-04 2.9e-02 3.9e-02
9 BLA gene expression LOC108348302 0.13 0.08 6.9e-05 0.04 0.08 0.05 0.06 3.5e-03 5.7e-05 1.3e-03 4.5e-04
10 NAcc mRNA stability LOC108348302 0.02 0.01 3.1e-03 0.01 0.02 0.01 0.01 1.0e-02 1.1e-03 1.1e-02 7.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density5.18.712.9-2.93.63.31.73.43.63.50.53.12.3
Area under the delay curve0.20.31.40.0-0.5-0.60.3-0.60.0-0.21.2-0.40.0
BMI with tail0.93.28.9-2.41.01.63.01.31.21.12.6-0.6-1.3
BMI without tail1.85.514.0-3.21.72.43.72.01.71.53.1-0.5-1.6
Body weight3.515.331.7-5.23.54.35.63.83.73.64.50.9-0.6
Weight adjusted by age0.81.32.3-1.31.31.51.41.50.90.90.6-0.1-1.0
Bone surface2.54.56.6-2.42.52.41.72.42.62.50.91.91.3
Bone volume3.86.89.9-2.93.23.02.13.03.13.01.02.31.4
Breakpoint value in progressive ratio session0.91.12.00.9-1.3-1.0-0.2-1.0-1.4-1.1-0.0-1.3-1.1
Number of licking bursts0.20.40.80.5-0.9-0.80.1-0.9-0.1-0.00.80.10.9
Context. condit. distance diff. score0.40.41.60.50.1-0.1-0.8-0.00.50.2-0.71.01.3
Locomotion velocity, session 11.01.12.00.4-1.2-1.00.2-1.2-1.1-1.11.1-1.4-1.0
Locomotion distance, session 10.20.20.40.6-0.5-0.6-0.5-0.6-0.1-0.20.00.20.6
Locomotion velocity, session 21.11.35.0-0.8-0.5-0.01.5-0.4-0.5-0.52.2-1.4-1.4
Locomotion distance, session 20.50.61.11.0-1.0-1.0-1.0-1.0-0.6-0.7-0.5-0.20.4
Locomotion velocity, session 31.92.13.01.7-1.6-1.7-1.6-1.7-1.6-1.6-0.9-0.9-0.3
Locomotion distance, session 30.91.02.1-0.11.00.7-0.60.91.00.9-1.11.41.3
Stereotopy head waving bouts, day 32.42.85.02.2-2.0-2.2-2.1-2.1-1.0-1.1-1.00.11.4
Stereotopy head waving duration, day 31.41.73.41.6-1.8-1.9-1.3-1.8-0.9-1.0-0.2-0.30.8
Locomotion velocity, session 71.11.21.71.2-1.2-1.2-1.2-1.2-1.2-1.3-0.9-0.9-0.5
Locomotion distance, session 70.50.71.11.1-1.0-1.0-0.9-1.0-0.6-0.8-0.6-0.40.1
Stereotopy head waving bouts, day 70.20.20.80.40.0-0.2-0.7-0.10.20.2-0.60.70.9
Stereotopy head waving duration, day 70.10.20.30.5-0.4-0.5-0.6-0.4-0.4-0.4-0.3-0.10.1
Locomotion velocity, session 83.23.96.62.3-2.5-2.5-1.7-2.6-2.0-2.2-0.5-1.5-0.5
Locomotion distance, session 80.10.20.70.5-0.3-0.4-0.5-0.40.1-0.1-0.20.40.9
Degree of sensitization distance1.51.52.71.0-1.6-1.4-0.3-1.5-1.4-1.40.2-1.4-1.0
Degree of sensitization stereotypy0.60.61.1-0.51.00.80.11.00.90.9-0.31.00.8
Conditioned locomotion0.10.20.70.30.00.0-0.30.00.10.3-0.40.70.8
Cocaine response after cond. corrected0.40.51.80.50.30.0-1.10.2-0.00.2-1.30.80.8
Cocaine response after cond. not corrected0.80.92.41.3-0.7-0.9-1.5-0.8-0.9-0.8-1.3-0.10.2
Cocaine response before conditioning2.12.54.41.2-2.1-1.8-0.4-1.9-1.6-1.90.6-1.9-1.3
Saline control response0.20.30.6-0.50.80.60.10.70.50.5-0.10.40.2
Bone: connectivity density5.28.112.1-3.03.53.32.13.33.43.31.02.61.7
Bone: cortical apparent density0.10.10.5-0.20.10.20.10.2-0.2-0.20.2-0.5-0.7
Bone: cortical area4.26.510.5-3.23.13.22.83.22.42.61.21.3-0.1
Bone: cortical porosity0.30.30.60.1-0.6-0.50.4-0.6-0.4-0.40.7-0.8-0.7
Bone: cortical porosity0.10.20.6-0.0-0.4-0.40.4-0.4-0.1-0.20.8-0.5-0.3
Bone: cortical thickness3.35.49.1-2.62.92.91.93.02.52.60.42.00.9
Bone: cortical thickness3.84.59.3-1.22.11.70.22.12.72.5-0.93.02.8
Bone: cortical tissue density0.10.10.5-0.1-0.00.00.00.0-0.3-0.30.2-0.5-0.7
Condit. Reinf. active minus inactive responses1.41.52.9-0.91.10.90.51.11.71.60.31.71.7
Condit. Reinf. active-inactive response ratio3.13.36.1-1.11.91.70.41.92.32.2-0.62.52.2
Condit. Reinf. active responses0.91.12.0-0.90.80.70.90.81.41.31.01.11.2
Condit. Reinf. inactive responses0.50.62.6-0.90.10.31.20.1-0.00.01.6-0.7-0.9
Incentive salience index mean0.60.81.9-0.90.40.41.10.41.01.01.40.70.9
Condit. Reinf. lever presses0.60.84.9-0.8-0.4-0.21.5-0.30.20.32.2-0.30.1
Condit. Reinf. active minus inactive responses0.10.10.50.20.10.0-0.60.10.0-0.2-0.70.20.1
Condit. Reinf. active-inactive response ratio0.10.10.3-0.50.40.40.20.40.30.20.20.1-0.1
Condit. Reinf. active responses0.60.81.41.1-0.8-0.9-1.2-0.9-0.8-1.1-0.9-0.6-0.4
Condit. Reinf. inactive responses2.33.04.52.0-1.8-1.8-1.7-1.8-2.0-2.1-1.1-1.4-1.0
Condit. Reinf. lever presses0.91.32.40.6-1.3-1.00.0-1.1-1.4-1.40.4-1.5-1.4
Condit. Reinf. lever reinforcers received0.40.61.10.8-0.7-0.7-0.7-0.7-0.8-1.0-0.5-0.7-0.7
Conditioned reinforcement - actives1.22.14.0-2.01.81.91.61.71.41.31.00.4-0.4
Conditioned reinforcement - inactives4.87.012.1-3.53.43.42.73.22.72.71.41.2-0.2
Conditioned locomotion1.11.43.2-1.81.41.41.41.21.31.11.00.2-0.3
Patch foraging indifference point 0 sec0.81.45.8-0.9-0.8-0.41.7-0.7-0.2-0.42.4-1.4-1.2
Patch foraging indifference point AUC1.82.64.91.1-2.2-1.90.0-1.9-1.7-1.80.7-2.0-1.5
Delay disc. indifference point, 0s delay2.93.26.32.1-2.5-2.4-1.3-2.5-1.7-1.80.2-1.10.1
Delay disc. indifference point, 16s delay0.70.81.60.9-1.3-1.3-0.4-1.2-0.7-0.90.6-0.8-0.2
Delay disc. indifference point, 2s delay0.50.61.30.9-1.1-1.2-0.5-1.1-0.6-0.60.3-0.20.5
Delay disc. indifference point, 24s delay0.40.53.0-0.5-0.2-0.20.8-0.30.1-0.11.7-0.6-0.4
Delay disc. indifference point, 4s delay0.10.21.0-0.3-0.2-0.30.4-0.20.0-0.11.0-0.3-0.1
Delay disc. indifference point, 8s delay0.40.52.0-0.1-0.6-0.50.6-0.6-0.2-0.31.4-0.8-0.5
Indifference point function ln k1.93.35.3-2.12.32.21.32.12.02.10.71.60.9
Indifference point function log k1.93.35.3-2.12.32.21.32.12.02.10.71.60.9
Patch foraging total patch changes 0 sec1.01.98.3-1.3-0.6-0.12.3-0.40.1-0.12.9-1.4-1.3
Patch foraging total patch changes 12 sec1.31.73.00.5-1.7-1.40.5-1.6-1.1-1.31.3-1.7-1.2
Patch foraging total patch changes 18 sec2.43.66.51.6-2.5-2.3-0.8-2.2-2.2-2.3-0.1-2.0-1.4
Patch foraging total patch changes 24 sec0.30.51.40.4-1.2-1.00.1-1.0-0.4-0.70.4-0.8-0.4
Patch foraging total patch changes 6 sec1.72.64.70.3-2.0-1.60.9-1.8-1.3-1.52.1-2.2-1.6
Patch foraging time to switch 0 sec0.40.91.81.3-0.9-1.0-1.2-0.9-1.1-1.1-0.7-0.5-0.2
Patch foraging water rate 0 sec0.40.93.2-1.30.00.31.60.10.90.61.8-0.2-0.1
Patch foraging water rate 12 sec0.91.83.5-1.61.21.51.41.41.91.51.10.90.5
Patch foraging water rate 18 sec0.50.81.6-1.10.40.51.20.41.11.01.30.50.6
Patch foraging water rate 24 sec2.63.66.7-2.21.81.91.81.72.62.31.61.51.2
Patch foraging water rate 6 sec1.31.83.2-1.81.31.51.71.31.61.51.30.60.2
Seeking ratio, delayed vs. immediate footshock0.40.51.10.5-1.0-0.7-0.3-1.1-0.6-0.90.5-0.8-0.5
Distance traveled before self-admin0.40.51.5-0.2-0.40.00.8-0.3-0.2-0.51.2-1.0-1.0
Distance traveled after self-admin0.30.41.2-0.90.40.51.10.40.30.10.9-0.4-0.7
Extensor digitorum longus weight0.10.31.10.0-0.7-0.50.3-0.6-0.6-0.61.0-0.7-0.4
Bone: elastic displacement0.20.20.7-0.30.40.4-0.10.30.80.5-0.10.50.6
Bone: elastic work1.31.62.9-1.71.41.51.51.41.41.31.00.60.0
Bone: endosteal estimation0.20.52.2-0.8-0.00.21.3-0.0-0.10.11.5-0.6-0.7
Bone: endosteal perimeter0.51.02.0-1.41.11.21.31.10.60.70.90.0-0.6
Epididymis fat weight1.44.810.5-3.02.02.53.22.21.71.72.6-0.1-1.2
Delta time in closed arm before/after self-admin0.40.31.00.0-0.7-0.60.5-0.7-0.5-0.41.0-0.6-0.2
Delta time in open arm before/after self-admin0.30.30.90.9-0.5-0.4-0.8-0.3-0.6-0.4-0.8-0.1-0.1
Diff in mean of infusions in LGA sessions1.72.04.90.1-1.4-0.90.8-1.0-1.6-1.41.2-2.2-2.2
Delay discount exponential model param0.20.21.30.30.20.3-0.50.3-0.3-0.1-1.20.2-0.1
Extinction: sum of active levers before priming0.10.10.20.2-0.3-0.20.3-0.2-0.00.00.4-0.3-0.1
Active lever presses in extinction session 60.20.20.40.5-0.4-0.4-0.3-0.4-0.7-0.5-0.3-0.3-0.3
Bone: final force2.74.310.6-2.81.72.13.31.91.71.82.60.3-0.4
Bone: final moment2.64.210.0-2.81.82.23.22.01.71.92.40.5-0.3
Food consumed during 24 hour testing period0.10.10.40.2-0.1-0.2-0.3-0.20.30.1-0.20.40.7
Glucose0.50.82.3-0.6-0.4-0.11.2-0.3-0.6-0.51.2-1.3-1.5
Heart weight2.43.75.9-1.32.42.10.32.32.32.2-0.52.41.9
Delay discount hyperbolic model param0.20.21.30.10.40.5-0.40.4-0.20.0-1.10.3-0.1
Intermittent access intake day 1-15 change1.12.24.0-1.32.01.80.51.91.91.7-0.71.50.7
Intermittent access intake escalation1.12.34.2-1.32.01.70.41.82.01.7-0.71.50.8
Intermittent access intake escalation 21.82.03.2-1.81.81.81.41.71.71.50.40.7-0.0
Intermitt. access day 1 inactive lever presses0.10.51.3-0.51.11.0-0.01.10.30.6-0.80.4-0.3
Intermitt. access day 15 inactive lever presses0.20.41.4-0.00.70.5-0.70.60.10.3-1.20.60.3
Intermitt. access escalation Index0.10.20.40.3-0.5-0.6-0.3-0.60.1-0.10.30.10.6
Intermittent access day 1 total infusions0.30.41.1-0.3-0.4-0.30.6-0.4-0.5-0.60.9-1.0-1.0
Intermittent access day 15 total infusions1.11.63.0-1.51.71.50.71.51.71.4-0.01.00.4
Intermittent access terminal intake (last 3 days)0.60.81.4-1.11.21.10.81.11.11.00.30.60.1
Intermittent access total infusions0.50.61.3-1.10.90.91.00.90.60.60.6-0.0-0.5
Intermittent access day 1 locomotion0.60.71.7-1.00.20.41.30.30.0-0.11.3-0.9-1.3
Intermittent access day 15 total locomotion0.30.50.8-0.80.90.80.70.80.70.70.30.3-0.0
Intermittent access total locomotion0.70.81.8-1.30.91.01.30.90.60.51.0-0.3-0.9
Intermittent access standard deviation0.40.91.6-1.21.21.31.01.01.11.00.50.4-0.0
Left kidney weight0.31.33.5-0.4-0.8-0.21.3-0.4-0.8-0.81.7-1.7-1.9
Right kidney weight0.83.59.1-2.10.31.23.00.8-0.00.02.7-1.9-2.8
Cocaine induced anxiety0.91.23.00.1-1.0-0.80.2-0.9-1.3-1.50.3-1.6-1.7
Post-drug Anxiety0.60.71.40.5-0.9-0.8-0.3-0.9-1.0-1.2-0.1-1.0-0.9
Baseline Anxiety0.30.41.50.7-0.1-0.3-0.8-0.30.30.3-0.50.81.2
Tail length0.72.96.5-2.31.51.92.51.51.51.32.20.0-0.6
Length with tail1.46.111.4-3.32.52.83.42.62.22.32.60.7-0.4
Length without tail1.34.37.1-2.32.62.51.72.72.12.40.51.80.9
Times rat made contact with spout0.10.10.4-0.0-0.4-0.40.1-0.30.10.10.60.10.5
Lifetime Intake0.91.12.4-1.51.21.21.31.10.90.90.90.1-0.5
Liver weight, left0.10.10.60.40.0-0.0-0.40.1-0.2-0.3-0.80.0-0.2
Liver weight, right1.42.55.9-2.11.31.82.41.60.70.91.6-0.5-1.6
Locomotor activity0.71.21.8-1.31.00.91.11.01.31.21.20.90.8
Locomotor testing distance0.91.73.0-1.11.51.20.51.31.71.60.51.61.4
Locomotor testing rearing0.30.61.4-0.80.60.50.80.61.00.81.20.50.5
Locomotion in novel chamber0.40.51.4-0.90.10.31.20.10.90.61.00.00.1
Locomotion in novel chamber post-restriction2.43.97.4-1.62.12.01.51.92.72.60.92.01.8
Fecal boli incidents, locomotor time 10.10.20.8-0.3-0.3-0.10.7-0.2-0.1-0.10.9-0.6-0.6
Change in fecal boli incidents, locomotor task2.12.13.41.8-1.7-1.7-1.3-1.7-1.8-1.6-0.5-0.9-0.3
Time >=10cm from walls, locomotor time 11.01.02.10.6-1.2-0.9-0.1-1.0-1.5-1.10.2-1.4-1.3
Bouts of movement, locomotor time 10.10.10.4-0.2-0.2-0.20.2-0.2-0.5-0.30.4-0.6-0.6
Total resting periods, locomotor time 10.10.10.20.0-0.3-0.3-0.0-0.3-0.4-0.30.2-0.4-0.4
Rest time, locomotor task time 10.10.20.50.4-0.7-0.6-0.1-0.7-0.2-0.40.3-0.20.1
Distance moved, locomotor task time 10.20.30.50.6-0.6-0.5-0.6-0.5-0.7-0.6-0.5-0.5-0.5
Vertical activity count, locomotor time 10.10.10.3-0.40.50.50.10.50.30.3-0.10.2-0.1
Time >=10cm from walls, locomotor time 20.60.92.61.2-0.4-0.5-1.5-0.4-0.0-0.1-1.60.81.1
Bouts of movement, locomotor time 20.50.81.60.9-1.3-1.2-0.9-1.2-0.7-0.9-0.6-0.6-0.2
Total resting periods, locomotor time 20.50.81.60.8-1.3-1.2-0.8-1.2-0.8-1.0-0.5-0.8-0.4
Rest time, locomotor task time 20.10.20.50.0-0.5-0.30.5-0.4-0.4-0.30.7-0.5-0.3
Distance moved, locomotor task time 20.20.31.50.10.30.3-0.70.40.10.1-1.20.30.1
Vertical activity count, locomotor time 20.71.02.4-0.11.00.7-0.90.90.90.8-1.51.31.0
Light reinforcement 10.20.60.90.3-1.0-0.70.3-0.8-0.9-0.80.7-0.9-0.7
Light reinforcement 21.21.94.20.9-1.5-1.5-0.2-1.4-2.0-1.70.6-1.7-1.4
Bone: marrow area0.20.52.2-0.8-0.10.11.3-0.1-0.00.11.5-0.6-0.6
Bone: maximum diameter1.12.03.3-1.81.71.81.61.71.41.50.80.70.0
Bone: maximum force3.15.512.4-3.22.22.53.52.32.02.22.70.6-0.3
Bone: maximum moment2.95.010.6-3.02.22.53.32.31.92.22.30.7-0.2
Mean time between licks in bursts1.02.45.1-2.01.41.72.31.41.11.32.10.1-0.5
Mean num. licks in bursts0.40.71.5-0.81.21.00.11.20.80.7-0.60.70.1
Cd content in liver5.25.89.5-2.02.82.61.12.83.12.9-0.32.82.1
Co content in liver0.10.20.30.5-0.5-0.4-0.5-0.40.1-0.2-0.50.00.2
Cu content in liver0.60.71.80.8-0.6-0.7-1.2-0.60.1-0.0-0.90.81.3
Fe content in liver0.50.61.41.0-0.6-0.7-1.2-0.6-1.0-0.7-1.2-0.2-0.1
K content in liver2.01.93.61.7-1.8-1.9-1.5-1.9-1.0-1.3-0.7-0.60.3
Mg content in liver0.20.20.40.5-0.4-0.4-0.5-0.4-0.0-0.2-0.60.10.3
Mn content in liver0.20.20.4-0.30.60.60.00.60.60.4-0.40.40.1
Na content in liver0.80.91.71.1-1.2-1.2-0.6-1.3-1.0-1.00.1-0.7-0.2
Rb content in liver1.31.52.8-0.71.41.30.11.41.41.4-0.81.71.3
Se content in liver0.30.41.80.8-0.3-0.3-1.0-0.2-0.2-0.2-1.30.20.3
Sr content in liver0.40.30.7-0.50.90.80.50.80.30.30.3-0.1-0.6
Zn content in liver0.10.20.40.2-0.3-0.2-0.3-0.3-0.3-0.5-0.4-0.6-0.7
Bone: minimum diameter1.73.27.2-2.51.82.02.71.81.11.31.9-0.0-1.0
Time in familiar zone, hab. session 10.60.61.2-1.00.70.81.10.70.60.50.9-0.2-0.6
Time in novel zone, hab. session 10.90.93.4-0.00.70.4-0.50.51.00.9-0.51.61.9
Total zone transitions, hab. session 10.10.20.8-0.1-0.5-0.30.6-0.5-0.1-0.10.9-0.4-0.2
Total locomotion distance, hab. session 10.10.20.6-0.3-0.00.10.6-0.10.60.40.80.20.5
Locomotion velocity, hab. session 10.10.20.60.0-0.5-0.40.5-0.6-0.1-0.20.8-0.4-0.1
Time in familiar zone, hab. session 20.40.41.0-0.91.00.90.50.90.40.40.30.2-0.2
Time in novel zone, hab. session 20.20.20.60.30.10.1-0.40.10.40.4-0.80.60.7
Total zone transitions, hab. session 20.10.10.60.4-0.1-0.1-0.5-0.1-0.3-0.1-0.80.10.1
Total locomotion distance, hab. session 20.70.91.9-0.20.90.8-0.30.81.01.0-0.81.41.3
Locomotion velocity, hab. session 20.30.41.1-0.10.60.5-0.20.50.80.8-0.51.01.0
Novel to familiar place preference ratio0.20.20.6-0.70.50.50.80.50.30.40.40.0-0.3
Novelty place preference0.10.10.3-0.40.30.30.50.30.10.20.3-0.0-0.2
Time in novel zone, NPP test0.00.00.1-0.30.20.20.30.30.10.20.10.1-0.1
Total zone transitions, NPP test0.20.30.70.6-0.8-0.8-0.3-0.8-0.1-0.10.10.20.8
Total locomotion distance, NPP test0.30.52.50.3-0.1-0.3-0.4-0.30.60.50.01.01.6
Locomotion velocity, NPP test0.20.31.10.4-0.6-0.6-0.2-0.60.20.10.30.41.0
Intraocular pressure0.71.12.0-1.01.41.40.41.40.91.2-0.21.00.6
Delta distance traveled before/after self-admin0.40.41.0-1.00.70.70.90.70.10.40.30.0-0.5
Delta ambulatory time before/after self-admin0.10.10.1-0.30.30.20.10.3-0.30.0-0.40.1-0.2
Parametrial fat weight1.63.79.9-2.51.21.73.11.50.50.62.9-1.1-2.0
Pavlov. Cond. lever latency0.40.51.5-0.11.00.8-0.60.80.20.2-1.20.50.0
Pavlov. Cond. magazine entry latency0.20.21.1-0.50.00.10.80.00.40.31.1-0.1-0.1
Pavlov. Cond. change in total contacts0.50.52.7-0.1-0.9-0.60.9-0.70.20.11.7-0.30.3
Pavlov. Cond. index score0.40.51.90.0-0.9-0.70.6-0.8-0.1-0.31.4-0.6-0.2
Pavlov. Cond. latency score0.60.81.80.4-1.3-1.20.4-1.3-0.4-0.61.3-0.8-0.1
Pavlov. Cond. lever contacts0.50.62.1-0.0-1.0-0.70.8-0.8-0.4-0.41.4-0.9-0.5
Pavlov. Cond. magazine entry number0.20.31.40.6-0.0-0.2-0.9-0.0-0.3-0.2-1.20.30.3
Pavlov. Cond. intertrial magazine entries2.53.06.7-0.71.81.4-0.31.62.11.9-0.82.62.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.50.1-0.9-0.70.5-0.8-0.2-0.31.2-0.6-0.2
Pavlov. Cond. response bias0.30.31.8-0.5-0.2-0.10.9-0.20.30.31.3-0.2-0.0
Pavlov. Cond. lever latency1.31.83.8-0.51.41.1-0.41.21.71.5-0.82.01.9
Pavlov. Cond. magazine entry latency0.81.02.10.6-1.1-0.80.2-0.9-1.2-1.10.3-1.4-1.4
Pavlov. Cond. change in total contacts1.11.83.00.9-1.7-1.4-0.0-1.5-1.6-1.60.6-1.7-1.4
Pavlov. Cond. index score1.52.04.00.7-1.7-1.20.3-1.4-1.7-1.60.8-2.0-1.8
Pavlov. Cond. latency score1.52.03.40.9-1.7-1.40.0-1.5-1.7-1.60.5-1.9-1.6
Pavlov. Cond. lever contacts1.42.03.60.8-1.6-1.30.1-1.4-1.8-1.70.6-1.9-1.7
Pavlov. Cond. magazine entry number1.21.53.8-0.21.20.7-0.80.91.41.2-1.01.91.9
Pavlov. Cond. intertrial magazine entries0.30.40.7-0.50.80.6-0.00.60.80.6-0.10.80.8
Pavlov. Cond. lever-magazine prob. diff.1.41.93.90.6-1.6-1.20.5-1.3-1.6-1.50.9-2.0-1.8
Pavlov. Cond. response bias1.41.94.10.4-1.4-0.90.5-1.1-1.7-1.50.9-2.0-2.0
Time in closed arm before self-admin0.91.13.2-1.20.40.71.50.5-0.2-0.31.5-1.2-1.8
Time in closed arm after self-admin0.70.71.7-1.30.70.81.30.70.40.31.2-0.4-0.8
Time in open arm before self-admin0.10.10.4-0.10.0-0.1-0.1-0.10.30.3-0.10.40.6
Time in open arm after self-admin0.60.61.70.50.40.2-0.70.40.80.7-1.01.21.3
Bone: periosteal estimation1.53.16.0-2.41.92.12.42.01.51.71.60.5-0.3
Bone: periosteal perimeter2.44.17.2-2.62.62.72.22.61.81.90.90.9-0.3
Bone: post-yield work0.10.10.4-0.30.20.20.20.30.30.50.00.60.7
Progressive ratio test 1 active lever presses0.60.72.2-0.6-0.4-0.11.2-0.3-0.4-0.31.5-1.1-1.2
Progressive ratio test 1 breakpoint0.50.62.0-0.6-0.3-0.11.1-0.3-0.3-0.21.4-1.0-1.1
Progressive ratio test 1 inactive lever presses0.71.02.1-1.31.41.40.91.30.70.80.40.0-0.8
Progressive ratio test 2 active lever presses0.30.30.6-0.80.40.60.80.40.30.20.7-0.4-0.7
Progressive ratio test 2 breakpoint0.20.30.5-0.70.40.50.70.40.40.20.7-0.3-0.6
Progressive ratio test 2 inactive lever presses0.30.51.0-1.00.90.90.80.70.70.80.50.30.0
Incentive Sensitization - Responses0.00.00.1-0.30.10.20.30.00.30.10.4-0.1-0.1
Incentive Sensitization - Breakpoint0.00.00.0-0.10.00.10.10.00.20.10.2-0.1-0.1
Sum of active levers in priming session hrs 5-61.71.54.10.80.50.2-1.30.30.91.1-1.91.82.0
Progressive ratio0.20.20.80.20.30.3-0.40.30.30.3-0.90.70.6
Food seeking constrained by brief footshock2.93.67.7-0.52.01.5-0.51.72.22.1-1.52.82.6
Seeking ratio, punishment vs. effort0.81.22.3-0.71.10.80.20.91.51.40.11.41.4
Retroperitoneal fat weight2.08.616.8-3.92.83.34.13.02.72.63.40.6-0.7
Reaction time number correct0.50.91.5-1.10.81.11.20.91.21.00.90.2-0.2
Reaction time mean minus median0.61.52.61.0-1.5-1.4-0.3-1.4-1.6-1.50.2-1.4-1.0
Reaction time mean minus median AUC0.51.22.00.8-1.3-1.2-0.3-1.2-1.4-1.30.1-1.3-1.0
Reaction time num false alarms0.20.20.40.4-0.5-0.4-0.3-0.3-0.6-0.6-0.6-0.5-0.6
Reaction time num false alarms AUC0.30.50.80.7-0.8-0.7-0.6-0.6-0.8-0.8-0.9-0.5-0.5
Reaction time trials correct on left0.50.91.5-1.10.81.11.20.91.21.00.90.2-0.2
Reaction time trials on left0.50.91.7-1.20.71.11.30.91.20.90.90.1-0.3
Reaction time mean0.40.62.40.0-0.3-0.20.3-0.2-1.2-0.80.2-1.2-1.5
Reaction time mean AUC0.91.53.40.7-1.1-0.9-0.2-0.9-1.8-1.4-0.0-1.7-1.8
Median of all reaction times0.20.31.6-0.10.10.20.20.2-0.8-0.4-0.1-0.8-1.2
Reaction time omissions1.21.74.5-0.1-1.1-0.71.0-0.8-1.4-1.21.3-2.0-2.1
Reaction time false alarm rate0.30.40.60.7-0.6-0.7-0.7-0.5-0.7-0.6-0.8-0.20.0
Reaction time premature initiation rate0.30.41.00.7-0.7-1.0-0.5-0.9-0.4-0.40.00.00.6
Reaction time premature initiations0.10.10.5-0.0-0.3-0.30.4-0.40.1-0.00.7-0.20.1
Std. dev. reaction times0.50.92.30.2-0.8-0.60.3-0.7-1.3-1.10.4-1.4-1.5
Reaction time trials completed0.50.91.7-1.20.71.11.30.91.20.90.90.1-0.3
Reaction time trials AUC0.61.22.3-1.40.91.31.51.11.31.01.10.1-0.4
Run reversals in cocaine runway, females1.61.53.1-1.71.31.41.81.31.11.01.30.1-0.5
Run reversals in cocaine runway, males1.41.42.31.3-1.3-1.3-1.4-1.3-1.5-1.3-1.1-0.6-0.2
Latency to leave start box in cocaine runway0.30.31.2-0.80.30.40.90.20.50.31.1-0.2-0.3
Latency to leave start box in cocaine runway, F0.60.71.3-1.10.70.81.20.61.00.81.10.20.0
Latency to leave start box in cocaine runway, M0.40.40.60.4-0.8-0.7-0.2-0.7-0.7-0.80.1-0.7-0.5
Std. dev. time between licks in bursts1.62.23.6-1.81.51.71.91.51.61.51.70.70.3
Total sessions with >9 infusions1.21.52.7-1.61.31.51.61.41.01.01.1-0.0-0.8
Short access day 1 total inactive lever presses2.33.05.4-2.02.32.21.32.11.82.10.61.20.5
Short access day 10 total inactive lever presses1.12.74.21.6-1.8-1.8-1.6-1.8-2.1-1.9-1.1-1.4-1.0
Short access day 1 total infusions3.64.77.6-2.82.52.62.42.52.32.31.71.10.1
Short access day 10 total infusions1.62.03.4-1.71.61.51.41.41.81.61.10.90.6
Short access total infusions1.11.42.8-1.71.11.21.61.11.11.01.40.1-0.4
Short access day 1 locomotion4.04.97.8-2.82.72.82.42.72.22.21.60.9-0.2
Short access day 10 total locomotion2.24.16.7-2.32.62.61.82.42.52.30.81.30.4
Short access total locomotion2.32.74.3-2.12.02.01.71.91.91.70.90.90.2
One hour access (0.3 mA shock)1.21.32.8-1.11.21.00.71.01.71.50.51.21.1
Compulsive drug intake0.70.81.71.3-0.9-1.1-1.3-0.8-0.6-0.6-0.80.20.7
One hour access (shock baseline)1.31.93.8-2.01.61.61.61.51.51.41.00.4-0.2
Social response proportion4.14.68.4-1.62.32.30.92.42.92.6-0.12.62.1
Social responses2.73.57.3-1.31.91.70.81.82.72.30.22.32.1
Social time0.40.51.50.60.1-0.1-0.90.20.50.4-0.91.01.2
Soleus weight0.51.56.7-1.0-0.5-0.02.0-0.2-0.2-0.02.6-1.2-1.2
Bone: stiffness1.42.35.7-2.11.41.62.41.51.01.31.70.2-0.5
Tibialis anterior weight0.10.41.3-0.90.50.61.00.60.40.51.10.1-0.0
Time to tail flick, vehicle, before self-admin0.30.30.5-0.50.70.4-0.10.70.60.6-0.60.60.3
Time to tail flick, vehicle, after self-admin0.20.21.1-0.10.10.30.20.2-0.5-0.4-0.2-0.6-1.0
Time to tail flick, test, before self-admin0.20.20.4-0.30.50.60.30.60.60.5-0.20.3-0.0
Time to tail flick, test, after self-admin0.70.82.51.2-0.7-0.8-1.3-0.6-0.3-0.5-1.60.20.4
Delta time to tail flick, vehicle, before/after SA0.10.10.20.3-0.2-0.0-0.1-0.2-0.4-0.50.1-0.4-0.4
Delta time to tail flick, test, before/after SA0.10.10.30.10.0-0.1-0.2-0.00.30.1-0.20.40.5
Tibia length0.20.61.4-1.00.50.71.20.50.70.81.00.30.2
Ambulatory time before self-admin0.71.03.4-0.5-0.50.01.3-0.4-0.3-0.61.9-1.4-1.5
Ambulatory time after self-admin0.70.92.2-1.20.30.61.50.50.1-0.01.5-0.8-1.2
Bone: tissue strength0.80.82.60.1-0.6-0.40.4-0.6-1.2-1.00.5-1.4-1.6
Total heroin consumption1.21.42.70.6-1.4-1.10.1-1.1-1.6-1.20.5-1.6-1.4
Bone: trabecular number5.18.512.2-3.23.43.32.43.33.53.41.42.51.7
Bone: trabecular spacing1.31.72.61.3-1.6-1.4-0.6-1.5-1.5-1.6-0.3-1.4-1.1
Bone: trabecular thickness2.63.24.8-1.82.01.91.22.02.22.20.61.91.5
Bone: trabecular tissue density0.71.11.80.7-1.3-1.1-0.1-1.1-1.2-1.20.4-1.4-1.1
Water consumed over 24 hours0.20.20.7-0.4-0.0-0.00.60.00.60.50.80.30.6
Number of responses in last shaping day1.41.52.8-1.11.21.11.11.11.71.60.71.31.2