Hub : Genes

LOC103694298

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC103694298 0.16 0.09 5.0e-14 0.13 0.14 0.15 0.14 4.5e-12 4.1e-13 1.4e-13 3.1e-13
2 PL gene expression LOC103694298 0.41 0.12 0.0e+00 0.25 0.26 0.27 0.27 7.8e-27 7.8e-28 2.4e-29 3.8e-30
3 pVTA gene expression LOC103694298 0.5 0.15 3.6e-11 0.23 0.26 0.26 0.27 3.1e-10 1.2e-11 1.5e-11 4.1e-12
4 BLA gene expression LOC103694298 0.37 0.13 0.0e+00 0.3 0.3 0.31 0.31 8.4e-17 2.3e-16 6.2e-17 4.2e-17
5 IL gene expression LOC103694298 0.29 0.16 2.4e-03 0.09 0.08 0.11 0.09 4.0e-03 7.1e-03 1.3e-03 3.6e-03
6 NAcc gene expression LOC103694298 0.18 0.09 0.0e+00 0.13 0.14 0.14 0.14 7.6e-15 3.4e-16 1.0e-15 1.4e-15
7 RMTg gene expression LOC103694298 0.2 0.13 6.6e-04 0.1 0.11 0.05 0.12 1.2e-03 8.8e-04 1.5e-02 4.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density2.23.64.72.2-2.1-1.8-1.82.0-1.8-1.4
Area under the delay curve0.80.81.1-1.01.10.90.8-0.70.90.9
BMI with tail1.96.17.4-2.52.72.62.6-2.72.51.6
BMI without tail0.30.61.0-0.50.80.80.7-1.00.60.8
Body weight0.83.58.0-1.81.81.72.1-2.81.50.3
Weight adjusted by age1.71.93.5-1.41.31.01.9-1.71.4-0.5
Bone surface0.50.92.00.9-1.0-0.7-0.91.4-0.7-1.0
Bone volume1.42.44.01.6-1.6-1.4-1.62.0-1.4-0.9
Breakpoint value in progressive ratio session1.01.12.11.0-1.2-1.1-0.90.7-1.1-1.5
Number of licking bursts0.40.50.80.7-0.7-0.7-0.70.6-0.8-0.9
Context. condit. distance diff. score1.72.03.3-1.51.41.31.8-1.51.7-0.2
Locomotion velocity, session 10.40.42.5-0.10.20.20.0-0.30.01.6
Locomotion distance, session 10.00.00.10.1-0.00.10.00.10.10.3
Locomotion velocity, session 20.00.00.00.00.00.20.10.00.10.0
Locomotion distance, session 20.10.10.7-0.10.10.20.5-0.80.10.1
Locomotion velocity, session 33.23.85.6-1.91.91.81.8-1.91.82.4
Locomotion distance, session 32.72.98.2-1.61.71.61.0-0.81.52.9
Stereotopy head waving bouts, day 31.31.62.2-1.41.41.51.3-0.71.50.9
Stereotopy head waving duration, day 31.21.52.1-1.31.21.41.5-1.01.4-0.0
Locomotion velocity, session 70.10.10.4-0.20.20.10.6-0.30.5-0.3
Locomotion distance, session 71.31.62.61.5-1.5-1.6-1.10.8-1.3-1.0
Stereotopy head waving bouts, day 73.74.16.0-2.32.32.51.6-0.82.32.0
Stereotopy head waving duration, day 72.02.44.5-1.61.71.90.8-0.11.62.1
Locomotion velocity, session 80.30.31.00.2-0.1-0.20.7-1.00.1-0.9
Locomotion distance, session 80.40.61.4-0.60.60.51.1-1.20.8-0.3
Degree of sensitization distance4.64.711.72.1-2.2-2.3-1.20.9-1.9-3.4
Degree of sensitization stereotypy4.04.46.2-2.32.42.51.6-1.12.32.2
Conditioned locomotion0.20.30.50.6-0.7-0.6-0.40.1-0.7-0.4
Cocaine response after cond. corrected0.50.62.1-0.40.40.51.0-1.50.50.2
Cocaine response after cond. not corrected0.80.93.0-0.50.60.71.1-1.70.60.6
Cocaine response before conditioning0.20.31.20.00.10.2-0.50.5-0.21.1
Saline control response4.76.211.62.6-2.8-2.6-1.61.0-2.5-3.4
Bone: connectivity density3.14.96.42.5-2.5-2.2-2.02.2-2.0-1.9
Bone: cortical apparent density0.30.41.0-0.30.40.60.10.80.61.0
Bone: cortical area0.00.00.1-0.0-0.00.1-0.10.3-0.00.0
Bone: cortical porosity0.30.41.6-0.30.40.30.3-0.70.21.3
Bone: cortical porosity0.80.93.9-0.60.70.70.4-0.60.52.0
Bone: cortical thickness0.10.10.3-0.20.20.30.10.10.20.6
Bone: cortical thickness0.20.20.60.6-0.4-0.20.3-0.4-0.2-0.8
Bone: cortical tissue density0.30.41.0-0.30.40.60.10.80.61.0
Condit. Reinf. active minus inactive responses4.55.114.3-2.02.32.41.2-0.62.13.8
Condit. Reinf. active-inactive response ratio3.13.46.6-1.71.91.91.4-1.51.72.6
Condit. Reinf. active responses2.53.012.1-1.31.51.70.40.31.43.5
Condit. Reinf. inactive responses1.61.95.41.2-1.2-0.9-1.72.3-1.10.6
Incentive salience index mean2.63.114.6-1.11.31.5-0.00.71.13.8
Condit. Reinf. lever presses1.41.88.20.10.00.3-1.11.8-0.02.9
Condit. Reinf. active minus inactive responses0.20.30.6-0.60.60.60.3-0.30.50.7
Condit. Reinf. active-inactive response ratio0.30.40.9-0.40.50.50.4-1.00.30.8
Condit. Reinf. active responses0.20.30.4-0.60.60.70.5-0.30.60.1
Condit. Reinf. inactive responses0.30.30.6-0.50.50.50.7-0.50.6-0.8
Condit. Reinf. lever presses0.50.71.0-1.00.80.91.0-0.70.9-0.5
Condit. Reinf. lever reinforcers received0.50.71.1-1.00.91.00.9-0.60.90.1
Conditioned reinforcement - actives0.60.61.8-0.40.30.30.9-1.20.3-1.3
Conditioned reinforcement - inactives1.41.62.4-1.31.31.31.5-1.31.40.2
Conditioned locomotion0.10.10.80.0-0.1-0.20.10.20.0-0.9
Patch foraging indifference point 0 sec0.81.42.7-1.11.11.11.4-1.61.10.1
Patch foraging indifference point AUC1.41.62.41.5-1.4-1.3-1.40.7-1.50.5
Delay disc. indifference point, 0s delay0.50.50.90.9-0.7-0.7-0.70.1-0.9-0.5
Delay disc. indifference point, 16s delay0.50.60.9-0.90.80.60.8-0.90.8-0.1
Delay disc. indifference point, 2s delay0.80.91.1-0.91.10.91.0-0.71.00.7
Delay disc. indifference point, 24s delay0.40.41.0-0.70.60.60.30.00.61.0
Delay disc. indifference point, 4s delay0.00.00.10.2-0.1-0.2-0.0-0.0-0.0-0.3
Delay disc. indifference point, 8s delay2.42.53.2-1.61.81.71.4-1.51.51.5
Indifference point function ln k1.62.33.7-1.61.71.81.7-0.81.90.5
Indifference point function log k1.62.33.7-1.61.71.81.7-0.81.90.5
Patch foraging total patch changes 0 sec1.11.73.7-1.31.21.21.6-1.91.20.0
Patch foraging total patch changes 12 sec0.40.60.91.0-0.8-0.8-0.90.5-0.80.2
Patch foraging total patch changes 18 sec1.92.43.71.9-1.8-1.7-1.60.8-1.9-0.0
Patch foraging total patch changes 24 sec0.30.40.60.7-0.7-0.7-0.50.1-0.8-0.2
Patch foraging total patch changes 6 sec0.10.10.30.3-0.3-0.3-0.1-0.6-0.50.3
Patch foraging time to switch 0 sec0.10.10.4-0.40.3-0.1-0.20.60.2-0.1
Patch foraging water rate 0 sec0.30.51.00.8-0.8-0.4-0.1-1.0-0.8-0.8
Patch foraging water rate 12 sec0.50.81.60.8-0.8-0.5-0.71.1-0.6-1.3
Patch foraging water rate 18 sec0.50.71.70.7-0.6-0.4-1.11.3-0.7-0.4
Patch foraging water rate 24 sec0.10.10.4-0.0-0.00.3-0.10.60.1-0.6
Patch foraging water rate 6 sec3.14.56.12.5-2.4-2.2-2.21.8-2.3-1.4
Seeking ratio, delayed vs. immediate footshock3.94.55.5-2.22.32.22.3-2.12.41.1
Distance traveled before self-admin1.92.02.7-1.51.61.61.3-0.91.51.4
Distance traveled after self-admin0.00.00.1-0.1-0.10.0-0.10.1-0.2-0.3
Extensor digitorum longus weight0.10.20.30.4-0.4-0.6-0.50.3-0.6-0.4
Bone: elastic displacement0.20.20.30.4-0.5-0.6-0.3-0.1-0.5-0.3
Bone: elastic work0.10.10.10.2-0.3-0.4-0.1-0.3-0.3-0.3
Bone: endosteal estimation0.10.21.0-0.10.0-0.10.2-0.10.1-1.0
Bone: endosteal perimeter0.10.20.4-0.40.20.20.6-0.60.4-0.6
Epididymis fat weight0.20.41.9-0.1-0.0-0.20.4-0.7-0.1-1.4
Delta time in closed arm before/after self-admin2.12.12.8-1.41.41.71.6-1.51.41.2
Delta time in open arm before/after self-admin3.93.85.42.1-2.2-2.3-1.91.2-2.1-1.6
Diff in mean of infusions in LGA sessions0.30.30.50.7-0.7-0.7-0.4-0.0-0.6-0.6
Delay discount exponential model param0.80.91.21.0-1.1-1.0-0.80.5-1.0-1.0
Extinction: sum of active levers before priming1.81.82.7-1.61.41.41.5-0.61.60.6
Active lever presses in extinction session 60.30.31.3-0.00.0-0.0-0.41.20.20.6
Bone: final force0.20.40.80.7-0.6-0.6-0.80.3-0.9-0.3
Bone: final moment0.10.10.30.3-0.3-0.3-0.50.1-0.6-0.2
Food consumed during 24 hour testing period5.36.48.02.8-2.7-2.7-2.82.4-2.8-0.8
Glucose0.60.93.20.8-1.0-0.8-0.2-0.4-0.9-1.8
Heart weight2.63.64.8-2.22.12.22.1-1.42.10.6
Delay discount hyperbolic model param0.90.91.21.0-1.1-1.0-0.80.6-1.0-1.1
Intermittent access intake day 1-15 change2.62.63.41.8-1.7-1.6-1.71.7-1.7-0.8
Intermittent access intake escalation3.83.74.82.2-2.0-1.9-2.22.1-2.0-0.7
Intermittent access intake escalation 21.81.72.61.5-1.3-1.2-1.61.6-1.3-0.1
Intermitt. access day 1 inactive lever presses1.31.44.9-1.01.01.10.60.51.22.2
Intermitt. access day 15 inactive lever presses0.60.71.0-0.90.80.90.8-0.01.01.0
Intermitt. access escalation Index0.10.10.40.4-0.2-0.1-0.40.7-0.30.3
Intermittent access day 1 total infusions1.92.23.3-1.71.51.41.8-1.31.6-0.3
Intermittent access day 15 total infusions0.30.31.30.3-0.4-0.5-0.20.3-0.3-1.1
Intermittent access terminal intake (last 3 days)0.20.21.2-0.10.00.00.30.00.0-1.1
Intermittent access total infusions0.30.32.0-0.2-0.1-0.10.3-0.2-0.0-1.4
Intermittent access day 1 locomotion0.50.51.1-1.10.90.70.8-0.10.90.2
Intermittent access day 15 total locomotion0.30.31.9-0.30.0-0.10.4-0.10.2-1.4
Intermittent access total locomotion0.30.41.7-0.50.20.20.5-0.40.3-1.3
Intermittent access standard deviation0.20.20.70.10.10.4-0.30.80.10.6
Left kidney weight0.00.10.20.2-0.1-0.4-0.5-0.0-0.4-0.1
Right kidney weight0.41.21.7-1.31.31.10.9-1.30.90.9
Cocaine induced anxiety0.91.03.7-0.50.70.61.2-1.90.7-0.3
Post-drug Anxiety0.60.71.1-0.60.80.81.0-1.10.70.6
Baseline Anxiety0.40.51.10.5-0.6-0.6-0.81.0-0.7-0.3
Tail length1.13.34.11.8-1.8-1.8-2.02.0-2.0-1.1
Length with tail0.10.52.20.3-0.4-0.6-0.2-0.2-0.7-1.5
Length without tail1.32.86.0-1.71.51.42.0-2.51.4-0.7
Times rat made contact with spout0.00.00.10.1-0.1-0.0-0.10.3-0.1-0.1
Lifetime Intake0.30.42.3-0.1-0.2-0.30.2-0.3-0.1-1.5
Liver weight, left0.71.14.30.6-0.8-0.50.3-1.3-0.7-2.1
Liver weight, right0.10.20.60.3-0.3-0.30.1-0.8-0.4-0.5
Locomotor activity0.20.41.6-0.30.40.20.6-1.20.2-0.6
Locomotor testing distance0.30.63.10.2-0.2-0.50.2-0.5-0.2-1.8
Locomotor testing rearing0.71.11.51.2-1.1-1.2-0.90.2-1.2-1.1
Locomotion in novel chamber0.91.21.6-1.21.31.21.2-0.91.10.4
Locomotion in novel chamber post-restriction0.10.10.4-0.20.10.2-0.20.50.10.6
Fecal boli incidents, locomotor time 11.71.92.41.4-1.5-1.5-1.30.7-1.5-1.4
Change in fecal boli incidents, locomotor task0.10.10.4-0.10.10.30.00.40.20.6
Time >=10cm from walls, locomotor time 10.00.10.1-0.30.30.1-0.10.20.10.4
Bouts of movement, locomotor time 11.71.93.11.3-1.5-1.5-1.51.8-1.2-0.4
Total resting periods, locomotor time 11.31.42.81.0-1.3-1.3-1.31.7-0.9-0.3
Rest time, locomotor task time 11.11.22.41.1-1.1-1.2-1.31.5-0.8-0.0
Distance moved, locomotor task time 10.40.40.7-0.70.70.70.9-0.60.7-0.2
Vertical activity count, locomotor time 10.20.30.70.5-0.5-0.4-0.3-0.0-0.7-0.8
Time >=10cm from walls, locomotor time 20.50.50.8-0.80.80.70.8-0.90.70.3
Bouts of movement, locomotor time 20.10.10.2-0.20.1-0.00.00.30.30.4
Total resting periods, locomotor time 20.10.10.30.2-0.3-0.4-0.30.6-0.10.1
Rest time, locomotor task time 21.92.23.11.7-1.6-1.8-1.41.6-1.2-1.1
Distance moved, locomotor task time 23.03.54.3-2.02.02.12.0-2.01.71.2
Vertical activity count, locomotor time 20.40.41.4-0.60.60.70.7-1.20.20.2
Light reinforcement 111.621.127.85.0-4.9-4.8-5.34.2-5.1-2.1
Light reinforcement 211.315.117.44.1-4.0-4.0-4.23.7-4.1-3.1
Bone: marrow area0.10.21.1-0.20.1-0.10.3-0.20.2-1.0
Bone: maximum diameter0.51.01.4-1.21.11.11.0-0.81.10.5
Bone: maximum force0.10.10.30.4-0.4-0.3-0.2-0.1-0.5-0.6
Bone: maximum moment0.00.10.30.1-0.1-0.00.0-0.2-0.2-0.6
Mean time between licks in bursts1.92.76.0-1.71.81.70.8-0.11.72.4
Mean num. licks in bursts0.30.30.8-0.50.50.60.40.10.70.9
Cd content in liver0.20.20.4-0.50.40.50.30.40.60.1
Co content in liver1.21.43.1-1.11.31.40.50.31.21.8
Cu content in liver0.30.40.6-0.80.70.80.5-0.20.70.7
Fe content in liver0.20.20.60.4-0.3-0.3-0.70.8-0.40.2
K content in liver0.40.40.8-0.90.90.80.6-0.40.60.3
Mg content in liver1.71.72.5-1.41.51.61.4-1.21.30.6
Mn content in liver0.30.30.8-0.40.40.20.7-0.90.4-0.7
Na content in liver0.10.20.6-0.40.10.20.3-0.5-0.1-0.8
Rb content in liver0.10.10.30.10.20.5-0.1-0.2-0.20.5
Se content in liver0.60.71.90.6-0.3-0.7-1.11.4-0.60.7
Sr content in liver0.40.31.0-0.60.50.60.3-0.30.41.0
Zn content in liver1.51.62.7-1.21.21.41.6-1.31.4-0.5
Bone: minimum diameter0.71.31.81.0-1.2-1.2-1.41.3-1.2-0.6
Time in familiar zone, hab. session 10.80.72.8-0.10.20.0-0.81.30.01.7
Time in novel zone, hab. session 10.40.41.70.1-0.2-0.10.5-0.7-0.0-1.3
Total zone transitions, hab. session 10.20.20.9-0.20.30.40.6-0.90.30.1
Total locomotion distance, hab. session 10.10.10.50.00.0-0.10.4-0.70.1-0.3
Locomotion velocity, hab. session 10.10.10.7-0.00.1-0.00.5-0.90.1-0.1
Time in familiar zone, hab. session 21.41.52.61.1-1.0-1.2-1.51.6-1.10.6
Time in novel zone, hab. session 22.02.03.4-1.31.21.41.8-1.81.3-0.5
Total zone transitions, hab. session 20.00.10.20.00.00.50.3-0.20.20.2
Total locomotion distance, hab. session 20.10.10.50.4-0.4-0.20.2-0.7-0.3-0.2
Locomotion velocity, hab. session 20.20.20.40.6-0.6-0.40.0-0.7-0.5-0.3
Novel to familiar place preference ratio0.70.81.2-1.00.80.91.1-0.70.9-0.6
Novelty place preference0.40.40.8-0.60.50.50.9-0.60.6-0.9
Time in novel zone, NPP test0.60.61.0-0.90.80.81.0-0.60.9-0.4
Total zone transitions, NPP test0.20.20.5-0.30.40.70.5-0.50.40.4
Total locomotion distance, NPP test0.30.40.7-0.50.60.70.6-0.60.60.8
Locomotion velocity, NPP test0.00.00.1-0.00.10.20.2-0.40.10.2
Intraocular pressure2.84.05.6-2.22.02.12.4-1.82.30.5
Delta distance traveled before/after self-admin1.41.51.91.2-1.4-1.3-1.20.9-1.4-1.2
Delta ambulatory time before/after self-admin1.61.72.21.3-1.4-1.3-1.41.3-1.5-0.8
Parametrial fat weight0.10.21.2-0.20.20.10.3-1.10.00.4
Pavlov. Cond. lever latency0.50.61.80.6-0.7-0.9-0.40.1-0.7-1.3
Pavlov. Cond. magazine entry latency0.20.20.4-0.50.50.60.30.10.60.6
Pavlov. Cond. change in total contacts0.40.42.6-0.00.20.4-0.30.50.11.6
Pavlov. Cond. index score0.60.71.2-0.90.91.10.6-0.10.91.0
Pavlov. Cond. latency score0.30.40.6-0.60.60.80.40.00.70.7
Pavlov. Cond. lever contacts0.60.71.2-0.90.81.10.7-0.50.80.9
Pavlov. Cond. magazine entry number0.91.12.31.1-1.1-1.2-0.60.3-1.0-1.5
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.50.60.60.5-0.60.40.4
Pavlov. Cond. lever-magazine prob. diff.0.60.81.4-1.01.01.20.8-0.41.00.8
Pavlov. Cond. response bias1.51.82.9-1.41.41.71.0-0.51.41.6
Pavlov. Cond. lever latency0.20.20.40.6-0.5-0.60.1-0.7-0.4-0.2
Pavlov. Cond. magazine entry latency0.10.10.3-0.50.40.50.3-0.10.40.1
Pavlov. Cond. change in total contacts0.50.71.4-0.91.01.20.40.10.90.8
Pavlov. Cond. index score0.30.40.9-0.90.80.90.4-0.00.70.3
Pavlov. Cond. latency score0.20.30.6-0.70.60.80.30.10.50.3
Pavlov. Cond. lever contacts0.10.10.6-0.20.10.2-0.40.8-0.00.1
Pavlov. Cond. magazine entry number0.20.30.50.7-0.6-0.7-0.50.2-0.60.1
Pavlov. Cond. intertrial magazine entries0.81.11.61.2-1.2-1.1-1.00.4-1.3-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.61.1-1.00.91.00.4-0.00.80.5
Pavlov. Cond. response bias0.20.30.6-0.80.70.80.20.10.50.3
Time in closed arm before self-admin2.02.38.21.0-0.8-1.0-1.92.9-0.90.8
Time in closed arm after self-admin0.20.20.80.2-0.1-0.0-0.50.9-0.20.5
Time in open arm before self-admin3.03.36.9-1.71.71.82.1-2.61.60.5
Time in open arm after self-admin0.50.52.0-0.60.40.40.8-1.40.4-0.2
Bone: periosteal estimation0.10.10.60.1-0.2-0.3-0.10.3-0.1-0.8
Bone: periosteal perimeter0.10.20.4-0.50.40.40.6-0.40.6-0.2
Bone: post-yield work0.20.31.70.0-0.10.10.5-0.30.1-1.3
Progressive ratio test 1 active lever presses1.31.32.7-1.10.80.91.4-1.60.8-1.1
Progressive ratio test 1 breakpoint0.91.02.0-0.90.60.71.2-1.40.6-1.2
Progressive ratio test 1 inactive lever presses0.60.60.9-0.90.81.00.6-0.20.80.9
Progressive ratio test 2 active lever presses0.20.20.3-0.60.40.40.4-0.20.5-0.4
Progressive ratio test 2 breakpoint0.20.20.7-0.50.30.20.5-0.40.4-0.8
Progressive ratio test 2 inactive lever presses1.92.23.3-1.81.61.51.7-1.11.80.6
Incentive Sensitization - Responses0.30.30.70.5-0.5-0.6-0.40.3-0.4-0.8
Incentive Sensitization - Breakpoint0.40.40.80.5-0.6-0.7-0.50.4-0.5-0.9
Sum of active levers in priming session hrs 5-60.50.40.80.6-0.7-0.7-0.50.7-0.5-0.9
Progressive ratio1.31.62.41.4-1.4-1.5-0.80.4-1.2-1.6
Food seeking constrained by brief footshock1.92.33.01.7-1.6-1.5-1.71.6-1.6-0.7
Seeking ratio, punishment vs. effort0.20.31.2-0.10.20.3-0.50.60.01.1
Retroperitoneal fat weight0.20.72.4-0.50.3-0.01.0-1.50.2-1.1
Reaction time number correct1.21.82.3-1.31.41.51.3-1.01.41.4
Reaction time mean minus median1.41.82.5-1.41.51.21.4-1.61.21.1
Reaction time mean minus median AUC1.01.21.8-1.21.30.91.2-1.31.10.7
Reaction time num false alarms5.47.48.4-2.72.92.92.9-2.92.81.9
Reaction time num false alarms AUC5.17.07.9-2.62.82.82.7-2.72.72.2
Reaction time trials correct on left1.21.82.3-1.31.41.51.3-1.01.41.4
Reaction time trials on left1.42.02.5-1.41.41.61.4-1.21.41.5
Reaction time mean1.92.73.7-1.91.91.61.7-1.51.70.9
Reaction time mean AUC1.92.63.6-1.91.91.51.7-1.51.80.8
Median of all reaction times1.72.33.3-1.81.81.51.6-1.11.70.8
Reaction time omissions1.82.47.2-1.41.41.01.7-2.71.10.6
Reaction time false alarm rate1.72.32.8-1.51.71.51.6-1.71.61.0
Reaction time premature initiation rate3.64.87.02.3-2.2-2.2-2.62.6-2.2-0.3
Reaction time premature initiations1.21.72.71.4-1.3-1.2-1.61.7-1.20.3
Std. dev. reaction times1.31.93.8-1.31.41.11.5-2.01.20.8
Reaction time trials completed1.42.02.5-1.41.41.61.4-1.21.41.5
Reaction time trials AUC1.42.02.5-1.31.41.61.4-1.31.41.5
Run reversals in cocaine runway, females1.01.01.7-0.91.10.91.2-1.30.90.2
Run reversals in cocaine runway, males0.10.10.40.1-0.1-0.00.2-0.20.0-0.7
Latency to leave start box in cocaine runway0.40.42.00.4-0.4-0.30.3-0.7-0.3-1.4
Latency to leave start box in cocaine runway, F0.30.31.2-0.00.0-0.10.6-0.80.1-1.1
Latency to leave start box in cocaine runway, M1.51.42.11.4-1.4-1.2-1.00.0-1.5-1.2
Std. dev. time between licks in bursts0.30.31.00.2-0.2-0.2-0.70.8-0.31.0
Total sessions with >9 infusions0.50.61.2-1.10.80.80.8-0.30.90.2
Short access day 1 total inactive lever presses0.50.61.10.7-1.0-1.0-0.5-0.1-0.8-0.9
Short access day 10 total inactive lever presses0.40.40.90.4-0.4-0.4-0.81.0-0.40.8
Short access day 1 total infusions1.31.42.2-1.51.21.11.4-1.21.3-0.1
Short access day 10 total infusions0.50.52.90.3-0.5-0.40.2-0.4-0.4-1.7
Short access total infusions0.30.42.20.1-0.3-0.40.2-0.4-0.2-1.5
Short access day 1 locomotion1.51.73.0-1.71.41.31.3-0.71.60.6
Short access day 10 total locomotion0.40.50.9-1.00.80.70.60.30.80.4
Short access total locomotion0.70.71.3-1.10.90.91.0-0.11.10.2
One hour access (0.3 mA shock)0.70.83.50.5-0.7-0.8-0.30.5-0.6-1.9
Compulsive drug intake1.31.42.31.1-1.1-1.2-1.31.5-1.1-0.4
One hour access (shock baseline)0.30.41.3-0.60.20.30.8-0.60.4-1.2
Social response proportion0.10.10.5-0.20.1-0.2-0.1-0.3-0.10.7
Social responses0.10.10.5-0.30.30.00.1-0.10.30.7
Social time1.62.14.01.3-1.3-1.6-1.82.0-1.30.5
Soleus weight0.10.20.70.2-0.2-0.5-0.30.7-0.2-0.8
Bone: stiffness0.10.10.60.1-0.1-0.10.2-0.8-0.2-0.5
Tibialis anterior weight0.62.12.7-1.61.61.71.5-0.91.71.0
Time to tail flick, vehicle, before self-admin1.31.32.31.5-1.2-1.1-0.80.5-1.0-1.5
Time to tail flick, vehicle, after self-admin1.61.72.61.6-1.4-1.3-1.20.9-1.4-1.3
Time to tail flick, test, before self-admin1.01.03.30.3-0.3-0.20.6-1.6-0.3-1.8
Time to tail flick, test, after self-admin0.40.50.70.8-0.8-0.8-0.70.5-0.7-0.3
Delta time to tail flick, vehicle, before/after SA0.20.20.40.4-0.4-0.4-0.50.6-0.40.2
Delta time to tail flick, test, before/after SA0.40.41.3-0.10.1-0.0-0.51.00.11.1
Tibia length0.72.03.8-1.61.61.51.5-1.91.00.5
Ambulatory time before self-admin1.61.72.1-1.41.51.41.4-1.11.40.7
Ambulatory time after self-admin0.40.50.70.7-0.7-0.7-0.70.4-0.8-0.6
Bone: tissue strength0.20.20.5-0.1-0.0-0.0-0.50.7-0.10.5
Total heroin consumption0.10.10.3-0.20.20.20.4-0.40.1-0.6
Bone: trabecular number2.23.45.42.1-2.0-1.7-1.82.3-1.7-1.1
Bone: trabecular spacing1.31.72.7-1.41.41.11.2-1.61.21.1
Bone: trabecular thickness2.93.54.42.0-2.1-1.8-1.81.8-1.9-1.5
Bone: trabecular tissue density0.40.61.7-0.50.50.51.1-1.30.5-0.5
Water consumed over 24 hours3.03.64.62.0-1.9-2.0-2.12.0-2.0-1.0
Number of responses in last shaping day4.44.56.0-2.42.22.42.4-1.72.41.2