Hub : Genes

LOC103693493

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA XR_005490598.1 0.38 0.14 0.0e+00 0.42 0.42 0.42 0.43 3.4e-51 6.1e-51 3.4e-51 2.9e-51
2 Liver intron excision ratio chr10_105806939_105807938 0.51 0.16 0.0e+00 0.52 0.52 0.52 0.52 3.2e-67 6.4e-67 2.0e-67 3.6e-67
3 Liver alternative polyA XR_005490598.1 0.41 0.14 0.0e+00 0.44 0.44 0.44 0.44 2.1e-53 1.4e-53 4.9e-54 5.8e-54
4 Liver mRNA stability LOC103693493 0.65 0.21 0.0e+00 0.45 0.45 0.44 0.44 1.5e-54 3.0e-55 3.6e-54 2.5e-54
5 Liver isoform ratio XR_005490599.1 0.4 0.14 0.0e+00 0.4 0.41 0.41 0.42 5.9e-48 5.9e-49 3.7e-49 9.4e-50
6 Liver isoform ratio XR_005490592.1 0.64 0.13 0.0e+00 0.63 0.63 0.63 0.64 6.6e-91 9.5e-91 3.2e-91 1.9e-91
7 Liver alternative polyA XR_005490596.1 0.66 0.15 0.0e+00 0.6 0.6 0.6 0.6 1.2e-83 1.3e-82 4.6e-83 3.3e-83
8 Liver alternative polyA XR_005490596.1 0.63 0.15 0.0e+00 0.59 0.58 0.58 0.59 7.2e-81 4.6e-80 3.0e-80 2.2e-80
9 Liver isoform ratio XR_594963.3 0.3 0.13 0.0e+00 0.3 0.29 0.29 0.29 4.6e-33 6.9e-32 2.2e-32 6.6e-33
10 Liver intron excision ratio chr10_105808180_105809225 0.07 0.04 2.6e-09 0.09 0.08 0.08 0.09 5.3e-10 2.3e-09 8.2e-09 1.0e-09
11 Liver intron excision ratio chr10_105808891_105809225 0.05 0.03 3.7e-05 0.04 0.04 0.03 0.04 3.2e-05 6.3e-05 5.8e-04 8.8e-05
12 Liver isoform ratio XR_005490596.1 0.69 0.13 0.0e+00 0.67 0.67 0.67 0.67 2.2e-101 3.2e-100 3.9e-100 3.2e-101
13 Liver gene expression LOC103693493 0.64 0.16 0.0e+00 0.52 0.53 0.53 0.53 3.3e-68 9.4e-69 2.4e-68 6.2e-69
14 Liver alternative polyA XR_005490592.1 0.11 0.06 1.7e-15 0.09 0.14 0.14 0.14 1.4e-10 4.0e-15 9.7e-15 7.8e-15
15 Liver alternative polyA XR_005490592.1 0.13 0.07 5.6e-17 0.09 0.15 0.15 0.15 2.5e-10 2.3e-16 4.2e-16 2.7e-16
16 Liver intron excision ratio chr10_105806237_105806868 0.41 0.13 0.0e+00 0.34 0.4 0.4 0.41 1.5e-38 8.0e-48 9.8e-48 2.6e-48
17 Liver isoform ratio XR_005490594.1 0.1 0.07 2.7e-09 0.08 0.09 0.08 0.08 4.2e-09 6.8e-10 1.4e-09 2.0e-09
18 Liver intron excision ratio chr10_105806237_105806398 0.43 0.14 0.0e+00 0.36 0.42 0.42 0.43 2.9e-41 4.7e-51 4.5e-51 1.4e-51
19 Liver isoform ratio XR_594962.3 0.03 0.02 4.1e-03 0 0.01 0.03 0 1.1e-01 6.8e-03 1.3e-04 8.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.20.40.60.60.6-0.6-0.7-0.70.60.70.7-0.7-0.70.70.7-0.7-0.3-0.3-0.7-0.10.80.6
Area under the delay curve2.02.12.6-1.6-1.61.61.61.4-1.5-1.5-1.51.51.5-1.5-1.61.51.51.41.11.3-1.20.4
BMI with tail0.82.54.71.51.7-1.6-1.8-1.81.61.71.7-1.7-1.71.71.8-1.7-1.0-0.9-2.2-0.41.9-0.1
BMI without tail6.713.922.63.63.9-3.7-4.1-4.14.04.14.1-4.1-4.14.14.1-4.2-2.3-2.1-4.8-0.94.70.5
Body weight4.619.222.44.74.7-4.6-4.7-4.74.74.64.6-4.6-4.64.64.6-4.6-4.1-4.0-4.3-3.54.1-1.3
Weight adjusted by age3.43.95.92.31.9-2.0-2.1-2.42.32.02.0-2.0-2.02.01.7-2.0-1.9-1.9-2.3-1.81.9-0.6
Bone surface0.30.50.70.80.8-0.8-0.8-0.60.70.80.8-0.8-0.80.80.8-0.8-0.7-0.8-0.2-0.80.4-0.3
Bone volume0.30.60.80.80.8-0.8-0.9-0.70.80.80.8-0.8-0.80.80.8-0.8-0.6-0.6-0.6-0.50.7-0.1
Breakpoint value in progressive ratio session0.30.41.30.60.6-0.6-0.5-0.50.40.40.4-0.4-0.40.40.4-0.3-0.9-0.9-0.7-1.00.2-1.1
Number of licking bursts0.20.20.40.40.5-0.5-0.6-0.50.50.60.6-0.6-0.60.60.6-0.6-0.2-0.2-0.3-0.10.60.0
Context. condit. distance diff. score1.01.23.40.80.8-0.7-1.1-1.31.21.01.0-1.0-1.01.01.0-1.20.00.1-1.80.71.81.5
Locomotion velocity, session 13.23.55.7-1.8-1.91.82.12.1-2.1-2.0-2.02.02.0-2.0-2.02.11.11.02.30.6-2.4-0.5
Locomotion distance, session 12.63.45.2-2.0-2.02.01.71.7-1.7-1.8-1.81.81.8-1.8-1.81.72.32.31.12.3-0.91.6
Locomotion velocity, session 25.66.57.9-2.7-2.72.62.72.8-2.7-2.7-2.72.72.7-2.7-2.72.72.22.22.81.8-2.60.7
Locomotion distance, session 20.40.62.1-0.8-0.80.80.60.5-0.5-0.6-0.60.60.6-0.6-0.60.51.11.10.21.30.11.4
Locomotion velocity, session 32.02.43.2-1.6-1.61.61.71.7-1.7-1.7-1.71.71.7-1.7-1.71.71.21.21.70.8-1.80.0
Locomotion distance, session 33.43.74.3-2.1-2.12.12.02.0-2.1-2.1-2.12.12.1-2.1-2.12.11.91.91.71.6-1.80.6
Stereotopy head waving bouts, day 30.70.91.5-0.9-0.90.91.01.1-1.0-1.0-1.01.01.0-1.0-1.01.00.60.51.20.2-1.2-0.4
Stereotopy head waving duration, day 30.40.40.7-0.7-0.70.70.70.8-0.7-0.7-0.70.70.7-0.7-0.70.70.50.50.80.3-0.8-0.4
Locomotion velocity, session 70.60.71.0-0.9-0.90.90.80.8-0.9-0.9-0.90.90.9-0.9-0.90.81.01.00.50.9-0.60.5
Locomotion distance, session 72.63.36.9-2.0-1.92.01.61.5-1.6-1.7-1.71.71.7-1.7-1.71.62.52.50.72.6-0.61.6
Stereotopy head waving bouts, day 70.20.20.40.50.5-0.5-0.5-0.50.50.50.5-0.5-0.50.50.5-0.5-0.4-0.3-0.6-0.30.5-0.3
Stereotopy head waving duration, day 70.40.50.70.80.8-0.8-0.8-0.70.70.70.7-0.7-0.70.70.7-0.7-0.8-0.8-0.4-0.80.4-0.6
Locomotion velocity, session 80.60.74.2-0.8-0.70.80.50.4-0.4-0.6-0.60.60.6-0.6-0.60.41.21.2-0.11.50.32.0
Locomotion distance, session 80.91.36.90.30.3-0.2-0.8-1.00.90.60.6-0.6-0.60.60.6-0.90.91.0-1.81.72.02.6
Degree of sensitization distance0.70.81.70.80.8-0.8-0.9-1.01.00.90.9-0.9-0.90.90.9-1.0-0.3-0.3-1.30.11.30.6
Degree of sensitization stereotypy0.60.61.10.80.8-0.8-0.9-0.90.80.80.8-0.8-0.80.80.8-0.8-0.6-0.6-1.0-0.40.9-0.1
Conditioned locomotion5.05.87.42.52.5-2.5-2.6-2.72.62.62.6-2.6-2.62.62.6-2.7-1.9-1.8-2.6-1.32.70.1
Cocaine response after cond. corrected0.10.10.2-0.3-0.30.30.40.3-0.4-0.4-0.40.40.4-0.4-0.40.40.00.00.1-0.0-0.4-0.4
Cocaine response after cond. not corrected0.60.70.9-0.9-0.90.90.90.9-1.0-0.9-0.90.90.9-0.9-0.91.00.60.60.80.4-0.90.0
Cocaine response before conditioning0.81.01.4-1.0-1.01.00.91.0-0.9-0.9-0.90.90.9-0.9-0.90.91.11.11.01.0-0.71.2
Saline control response3.54.65.32.32.3-2.3-2.3-2.22.32.32.3-2.3-2.32.32.3-2.3-2.1-2.0-1.9-1.82.0-0.5
Bone: connectivity density0.10.11.7-0.00.0-0.0-0.2-0.10.10.10.1-0.1-0.10.10.1-0.20.30.4-0.10.50.41.3
Bone: cortical apparent density2.83.74.4-2.0-2.12.12.02.0-2.1-2.1-2.12.12.1-2.1-2.12.11.81.81.71.5-1.9-0.3
Bone: cortical area7.010.612.53.53.5-3.5-3.4-3.23.33.43.4-3.4-3.43.43.4-3.3-3.4-3.4-2.6-3.32.5-1.3
Bone: cortical porosity1.11.26.90.90.8-0.9-0.4-0.30.40.50.5-0.5-0.50.50.5-0.3-1.6-1.70.2-2.1-0.6-2.6
Bone: cortical porosity1.21.35.51.11.0-1.1-0.7-0.70.70.80.8-0.8-0.80.80.8-0.6-1.7-1.7-0.2-2.0-0.2-2.3
Bone: cortical thickness5.48.812.33.23.2-3.3-3.0-2.82.93.13.1-3.1-3.13.13.1-2.9-3.5-3.5-2.0-3.51.8-1.7
Bone: cortical thickness1.92.22.71.61.6-1.6-1.5-1.51.41.51.5-1.5-1.51.51.5-1.4-1.6-1.6-1.3-1.61.1-0.9
Bone: cortical tissue density3.34.35.2-2.2-2.32.22.22.2-2.3-2.2-2.22.22.2-2.2-2.22.31.91.91.91.6-2.0-0.3
Condit. Reinf. active minus inactive responses2.62.93.41.81.8-1.8-1.8-1.81.81.81.8-1.8-1.81.81.8-1.8-1.5-1.5-1.8-1.21.8-0.1
Condit. Reinf. active-inactive response ratio1.21.31.81.21.2-1.2-1.3-1.31.21.21.2-1.2-1.21.21.2-1.2-1.0-1.0-1.3-0.81.2-0.4
Condit. Reinf. active responses4.65.66.62.52.5-2.5-2.5-2.52.62.52.5-2.5-2.52.52.5-2.6-2.1-2.1-2.4-1.62.4-0.0
Condit. Reinf. inactive responses1.11.31.61.21.2-1.2-1.2-1.21.31.21.2-1.2-1.21.21.2-1.3-1.0-1.0-1.2-0.71.20.1
Incentive salience index mean2.12.63.11.71.7-1.7-1.8-1.71.81.71.7-1.7-1.71.71.7-1.8-1.4-1.3-1.6-1.11.70.1
Condit. Reinf. lever presses0.10.10.50.10.2-0.2-0.3-0.30.30.20.2-0.2-0.20.20.2-0.30.20.2-0.40.30.50.7
Condit. Reinf. active minus inactive responses0.81.01.31.11.0-1.0-1.0-1.11.21.01.0-1.0-1.01.01.0-1.1-0.9-0.9-0.9-0.71.1-0.3
Condit. Reinf. active-inactive response ratio2.02.13.11.61.6-1.6-1.4-1.41.51.51.5-1.5-1.51.51.5-1.4-1.8-1.7-1.0-1.61.0-1.1
Condit. Reinf. active responses0.20.20.70.50.4-0.4-0.4-0.70.60.50.5-0.5-0.50.50.5-0.6-0.2-0.2-0.80.10.80.2
Condit. Reinf. inactive responses0.50.61.5-0.8-0.80.80.70.5-0.7-0.7-0.70.70.7-0.7-0.70.71.01.10.01.2-0.20.8
Condit. Reinf. lever presses0.30.41.70.50.4-0.4-0.6-0.80.70.50.5-0.5-0.50.50.5-0.6-0.00.0-1.30.41.20.3
Condit. Reinf. lever reinforcers received0.30.41.50.50.4-0.4-0.5-0.80.70.50.5-0.5-0.50.50.5-0.6-0.1-0.0-1.20.41.10.4
Conditioned reinforcement - actives0.20.20.70.40.2-0.2-0.4-0.80.80.20.2-0.2-0.20.20.3-0.50.10.1-0.80.20.80.7
Conditioned reinforcement - inactives1.31.52.11.41.2-1.3-1.3-1.51.41.11.1-1.1-1.11.11.1-1.2-1.4-1.4-1.3-1.31.20.0
Conditioned locomotion0.10.20.50.50.2-0.3-0.5-0.70.70.20.2-0.2-0.20.20.3-0.4-0.3-0.3-0.5-0.40.50.3
Patch foraging indifference point 0 sec0.10.20.30.40.4-0.4-0.5-0.50.40.40.4-0.4-0.40.40.4-0.4-0.4-0.3-0.6-0.30.4-0.3
Patch foraging indifference point AUC0.00.00.1-0.2-0.20.20.20.1-0.1-0.1-0.10.10.1-0.1-0.10.10.20.20.00.30.1-0.1
Delay disc. indifference point, 0s delay0.00.00.2-0.1-0.20.20.1-0.10.0-0.2-0.20.20.2-0.2-0.20.10.20.2-0.10.10.0-0.5
Delay disc. indifference point, 16s delay1.71.74.1-1.4-1.51.51.20.9-1.0-1.2-1.21.21.2-1.2-1.31.01.91.90.42.0-0.31.3
Delay disc. indifference point, 2s delay0.50.60.8-0.7-0.80.80.80.7-0.7-0.9-0.90.90.9-0.9-0.80.80.50.50.70.4-0.7-0.6
Delay disc. indifference point, 24s delay5.95.77.0-2.5-2.62.62.62.5-2.6-2.6-2.62.62.6-2.6-2.62.62.12.02.21.6-2.40.8
Delay disc. indifference point, 4s delay0.60.71.0-0.9-0.80.80.91.0-0.9-0.8-0.80.80.8-0.8-0.80.90.60.60.90.5-0.8-0.3
Delay disc. indifference point, 8s delay1.21.21.7-1.1-1.11.11.31.3-1.3-1.2-1.21.21.2-1.2-1.21.20.80.71.20.5-1.20.0
Indifference point function ln k0.70.91.3-1.0-1.11.10.90.9-1.0-1.0-1.01.01.0-1.0-1.01.01.11.10.61.0-0.70.8
Indifference point function log k0.70.91.3-1.0-1.11.10.90.9-1.0-1.0-1.01.01.0-1.0-1.01.01.11.10.61.0-0.70.8
Patch foraging total patch changes 0 sec0.10.20.60.40.4-0.4-0.5-0.50.40.40.4-0.4-0.40.40.4-0.4-0.3-0.2-0.8-0.10.6-0.1
Patch foraging total patch changes 12 sec0.00.10.90.10.0-0.10.00.0-0.0-0.0-0.00.00.0-0.00.00.0-0.2-0.2-0.0-0.2-0.1-0.9
Patch foraging total patch changes 18 sec0.10.10.9-0.3-0.30.30.1-0.1-0.1-0.2-0.20.20.2-0.2-0.20.10.60.7-0.50.90.50.3
Patch foraging total patch changes 24 sec0.70.91.71.00.9-0.9-1.1-1.21.10.90.9-0.9-0.90.90.9-1.0-0.8-0.7-1.3-0.61.10.3
Patch foraging total patch changes 6 sec0.30.51.00.70.7-0.7-0.7-0.60.60.60.6-0.6-0.60.60.6-0.6-0.9-0.9-0.3-1.00.3-0.8
Patch foraging time to switch 0 sec0.50.70.9-0.9-0.90.90.91.0-0.9-0.9-0.90.90.9-0.9-0.90.90.70.71.00.5-0.9-0.2
Patch foraging water rate 0 sec2.64.27.22.12.1-2.0-2.2-2.52.32.12.1-2.1-2.12.12.1-2.2-1.6-1.5-2.7-1.02.50.2
Patch foraging water rate 12 sec0.40.62.20.60.5-0.5-0.7-1.00.80.60.6-0.6-0.60.60.7-0.80.00.1-1.50.61.30.8
Patch foraging water rate 18 sec1.01.32.81.01.0-1.0-1.3-1.41.31.21.2-1.2-1.21.21.2-1.3-0.4-0.3-1.60.11.71.0
Patch foraging water rate 24 sec2.53.59.31.71.7-1.6-2.1-2.42.11.91.9-1.9-1.91.91.9-2.1-0.8-0.7-3.00.02.80.8
Patch foraging water rate 6 sec0.20.20.90.40.3-0.3-0.5-0.60.60.40.4-0.4-0.40.40.4-0.5-0.00.0-0.70.30.81.0
Seeking ratio, delayed vs. immediate footshock1.61.82.51.31.5-1.5-1.5-1.31.31.51.5-1.5-1.51.51.6-1.5-1.3-1.3-1.1-1.11.3-0.1
Distance traveled before self-admin1.41.52.51.31.3-1.3-1.1-1.11.01.11.1-1.1-1.11.11.1-1.0-1.5-1.5-1.1-1.60.6-1.4
Distance traveled after self-admin0.80.81.70.90.9-0.8-1.0-1.01.01.01.0-1.0-1.01.01.0-1.0-0.5-0.4-1.3-0.11.20.2
Extensor digitorum longus weight0.20.72.80.40.5-0.4-0.9-1.00.80.70.7-0.7-0.70.70.7-0.90.40.5-1.71.01.70.6
Bone: elastic displacement1.51.72.41.41.4-1.4-1.3-1.21.21.31.3-1.3-1.31.31.3-1.2-1.5-1.5-0.9-1.50.7-1.4
Bone: elastic work7.29.314.83.33.3-3.3-2.9-2.72.83.13.1-3.1-3.13.13.1-2.7-3.7-3.8-1.9-3.81.6-2.9
Bone: endosteal estimation0.10.20.80.10.1-0.1-0.4-0.40.30.30.3-0.3-0.30.30.3-0.40.40.5-0.80.80.90.7
Bone: endosteal perimeter0.81.62.01.41.4-1.4-1.4-1.31.31.41.4-1.4-1.41.41.4-1.3-1.3-1.3-1.0-1.21.0-0.1
Epididymis fat weight1.43.24.61.81.8-1.8-2.0-2.12.01.91.9-1.9-1.91.92.0-1.9-1.3-1.2-2.1-0.92.00.3
Delta time in closed arm before/after self-admin0.10.10.4-0.2-0.30.20.10.10.0-0.2-0.20.20.2-0.2-0.20.10.10.10.5-0.0-0.10.6
Delta time in open arm before/after self-admin0.20.20.90.30.3-0.2-0.3-0.50.30.30.3-0.3-0.30.30.3-0.30.20.2-0.90.30.60.1
Diff in mean of infusions in LGA sessions0.10.20.2-0.3-0.40.40.40.3-0.4-0.5-0.50.50.5-0.5-0.50.50.30.30.20.1-0.5-0.1
Delay discount exponential model param2.93.03.81.91.9-1.9-1.9-1.81.81.91.9-1.9-1.91.91.9-1.9-1.6-1.6-1.5-1.41.6-0.3
Extinction: sum of active levers before priming1.21.21.7-1.1-1.11.11.21.1-1.2-1.2-1.21.21.2-1.2-1.21.31.00.90.90.6-1.3-0.3
Active lever presses in extinction session 60.30.30.9-0.2-0.50.50.50.1-0.3-0.7-0.70.70.7-0.7-0.70.70.0-0.1-0.1-0.4-0.5-1.0
Bone: final force6.410.312.03.53.4-3.4-3.4-3.33.33.43.4-3.4-3.43.43.4-3.3-3.2-3.2-2.9-2.92.8-1.7
Bone: final moment7.311.913.83.73.7-3.7-3.6-3.53.53.63.6-3.6-3.63.63.6-3.5-3.6-3.5-3.1-3.22.8-2.1
Food consumed during 24 hour testing period0.60.71.00.90.9-0.9-0.9-0.90.90.80.8-0.8-0.80.80.8-0.8-0.7-0.7-1.0-0.50.9-0.8
Glucose4.06.011.7-2.3-2.32.32.92.8-2.8-2.6-2.62.62.6-2.6-2.62.91.10.92.80.2-3.4-1.5
Heart weight0.50.71.20.90.8-0.8-0.7-1.00.90.90.9-0.9-0.90.90.9-0.9-0.7-0.7-1.1-0.50.8-0.5
Delay discount hyperbolic model param2.72.93.61.81.8-1.9-1.9-1.81.81.81.8-1.8-1.81.81.8-1.8-1.6-1.6-1.5-1.41.5-0.2
Intermittent access intake day 1-15 change0.60.61.00.80.9-0.9-0.8-0.50.60.80.8-0.8-0.80.80.8-0.7-1.0-1.0-0.4-0.90.5-0.8
Intermittent access intake escalation0.60.60.80.80.9-0.9-0.9-0.60.70.80.8-0.8-0.80.80.8-0.8-0.9-0.8-0.6-0.70.7-0.6
Intermittent access intake escalation 21.81.83.51.31.4-1.4-1.3-0.90.91.21.2-1.2-1.21.21.2-1.1-1.8-1.8-0.6-1.90.5-1.8
Intermitt. access day 1 inactive lever presses1.21.32.01.41.2-1.2-1.1-1.41.31.01.0-1.0-1.01.00.9-1.1-1.3-1.3-1.4-1.21.1-0.6
Intermitt. access day 15 inactive lever presses1.61.72.91.41.2-1.2-1.4-1.71.71.31.3-1.3-1.31.31.2-1.5-0.9-0.9-1.7-0.61.70.4
Intermitt. access escalation Index1.51.32.71.11.0-1.0-1.2-1.51.51.11.1-1.1-1.11.11.1-1.3-0.5-0.4-1.6-0.11.61.0
Intermittent access day 1 total infusions0.30.40.60.50.7-0.7-0.7-0.50.50.70.7-0.7-0.70.70.8-0.6-0.5-0.5-0.4-0.40.5-0.1
Intermittent access day 15 total infusions0.70.81.10.91.0-1.0-1.0-0.91.01.01.0-1.0-1.01.01.0-1.0-0.8-0.8-0.9-0.61.0-0.2
Intermittent access terminal intake (last 3 days)1.31.41.71.21.3-1.3-1.3-1.21.21.21.2-1.2-1.21.21.3-1.2-1.3-1.2-1.0-1.11.0-0.7
Intermittent access total infusions0.60.70.90.80.9-0.9-0.9-0.80.90.90.9-0.9-0.90.91.0-0.9-0.7-0.7-0.7-0.50.8-0.1
Intermittent access day 1 locomotion0.40.40.80.70.6-0.6-0.8-0.90.90.60.6-0.6-0.60.60.7-0.7-0.5-0.4-0.8-0.30.90.5
Intermittent access day 15 total locomotion0.40.40.80.60.7-0.7-0.7-0.50.60.50.5-0.5-0.50.50.6-0.5-0.9-0.9-0.2-0.90.4-0.6
Intermittent access total locomotion0.40.50.70.80.7-0.8-0.8-0.80.80.60.6-0.6-0.60.60.7-0.7-0.8-0.8-0.6-0.70.70.1
Intermittent access standard deviation0.60.62.3-0.5-0.50.50.70.9-0.9-0.6-0.60.60.6-0.6-0.70.8-0.1-0.21.0-0.5-1.3-1.5
Left kidney weight0.10.21.10.40.3-0.4-0.2-0.20.30.20.2-0.2-0.20.20.2-0.2-0.7-0.80.4-1.1-0.2-0.5
Right kidney weight0.00.00.20.10.0-0.10.00.00.1-0.0-0.00.00.0-0.0-0.1-0.0-0.2-0.20.5-0.4-0.30.1
Cocaine induced anxiety3.94.58.62.42.1-2.2-2.0-2.11.91.91.9-1.9-1.91.92.0-1.8-2.8-2.9-1.9-2.91.3-1.5
Post-drug Anxiety0.30.31.30.70.5-0.5-0.4-0.50.40.40.4-0.4-0.40.40.4-0.3-1.0-1.0-0.6-1.10.20.0
Baseline Anxiety7.88.310.1-3.1-3.03.02.92.9-2.8-2.9-2.92.92.9-2.9-2.92.83.23.22.63.0-2.32.3
Tail length6.319.123.64.64.6-4.6-4.7-4.84.94.74.7-4.7-4.74.74.6-4.8-3.7-3.6-4.4-2.84.7-0.3
Length with tail2.810.312.93.63.4-3.5-3.3-3.33.53.33.3-3.3-3.33.33.3-3.3-3.6-3.6-2.3-3.52.4-1.4
Length without tail0.51.13.6-0.3-0.60.40.80.8-0.7-0.8-0.80.80.8-0.8-0.80.9-0.6-0.81.8-1.6-1.9-1.6
Times rat made contact with spout1.21.35.11.21.2-1.2-0.8-0.80.90.90.9-0.9-0.90.90.9-0.8-1.6-1.6-0.4-1.80.2-2.3
Lifetime Intake0.10.20.30.40.5-0.5-0.5-0.30.40.40.4-0.4-0.40.40.5-0.4-0.4-0.4-0.2-0.30.30.1
Liver weight, left0.20.41.4-0.3-0.30.20.50.6-0.6-0.5-0.50.50.5-0.5-0.40.7-0.2-0.30.9-0.6-1.1-1.2
Liver weight, right2.03.44.52.02.0-2.1-2.0-1.82.01.81.8-1.8-1.81.81.9-1.9-2.1-2.1-1.0-2.11.3-0.8
Locomotor activity0.60.91.2-1.0-1.01.01.00.9-1.0-1.0-1.01.01.0-1.0-1.11.01.00.90.70.8-0.8-0.1
Locomotor testing distance0.61.01.7-1.0-1.21.20.90.6-0.8-1.1-1.11.11.1-1.1-1.20.91.31.30.31.2-0.40.7
Locomotor testing rearing0.20.40.8-0.4-0.70.70.5-0.1-0.1-0.6-0.60.60.6-0.6-0.70.40.90.9-0.50.90.30.6
Locomotion in novel chamber0.20.21.4-0.3-0.40.40.40.0-0.1-0.3-0.30.30.3-0.3-0.40.20.70.7-0.10.8-0.01.2
Locomotion in novel chamber post-restriction2.22.63.71.61.9-1.8-1.6-1.11.31.91.9-1.9-1.91.91.7-1.7-1.7-1.7-0.8-1.41.1-0.3
Fecal boli incidents, locomotor time 10.60.60.8-0.9-0.80.80.70.7-0.7-0.9-0.90.90.9-0.9-0.80.80.90.90.60.8-0.50.8
Change in fecal boli incidents, locomotor task2.52.44.4-1.5-1.51.51.81.9-1.9-1.5-1.51.51.5-1.5-1.61.80.80.72.00.3-2.1-1.0
Time >=10cm from walls, locomotor time 10.80.81.50.60.9-0.8-0.8-0.50.61.21.2-1.2-1.21.21.1-1.1-0.1-0.1-0.40.30.91.0
Bouts of movement, locomotor time 12.02.22.9-1.6-1.61.61.61.7-1.7-1.5-1.51.51.5-1.5-1.41.61.41.41.51.2-1.60.9
Total resting periods, locomotor time 12.52.73.9-1.8-1.71.71.82.0-2.0-1.7-1.71.71.7-1.7-1.61.81.41.41.81.1-1.90.6
Rest time, locomotor task time 10.30.40.7-0.5-0.60.50.60.6-0.6-0.7-0.70.70.7-0.7-0.60.70.10.10.7-0.2-0.8-0.2
Distance moved, locomotor task time 10.70.81.20.90.8-0.8-0.9-0.90.91.11.1-1.1-1.11.11.1-1.0-0.5-0.5-0.9-0.30.9-0.5
Vertical activity count, locomotor time 11.61.62.31.21.2-1.2-1.4-1.41.41.51.5-1.5-1.51.51.5-1.5-0.6-0.6-1.5-0.21.5-0.1
Time >=10cm from walls, locomotor time 20.00.00.3-0.10.1-0.1-0.00.2-0.10.10.1-0.1-0.10.10.1-0.1-0.1-0.10.6-0.1-0.10.1
Bouts of movement, locomotor time 21.41.51.8-1.3-1.31.31.31.1-1.2-1.3-1.31.31.3-1.3-1.21.21.31.30.91.3-0.91.3
Total resting periods, locomotor time 20.91.02.4-1.0-1.01.01.00.8-0.8-1.0-1.01.01.0-1.0-0.90.91.21.20.61.3-0.51.6
Rest time, locomotor task time 20.10.10.4-0.3-0.20.20.30.4-0.4-0.2-0.20.20.2-0.2-0.20.30.20.20.60.1-0.50.2
Distance moved, locomotor task time 20.00.00.50.10.0-0.1-0.2-0.20.20.10.1-0.1-0.10.10.2-0.1-0.1-0.1-0.1-0.00.2-0.7
Vertical activity count, locomotor time 20.20.30.90.30.3-0.3-0.5-0.70.60.40.4-0.4-0.40.40.5-0.60.10.2-0.80.40.90.5
Light reinforcement 11.62.94.31.61.7-1.6-1.9-1.91.81.91.9-1.9-1.91.91.9-1.9-0.8-0.7-2.1-0.32.11.2
Light reinforcement 22.83.74.82.02.1-2.0-2.1-2.02.02.22.2-2.2-2.22.22.1-2.2-1.5-1.5-1.8-1.21.90.3
Bone: marrow area0.10.20.70.10.1-0.1-0.3-0.40.30.20.2-0.2-0.20.20.2-0.40.40.5-0.80.80.90.6
Bone: maximum diameter1.83.44.12.02.0-2.0-2.0-1.81.92.02.0-2.0-2.02.02.0-1.9-1.9-1.9-1.3-1.81.4-0.7
Bone: maximum force6.210.812.53.53.5-3.5-3.4-3.43.43.53.5-3.5-3.53.53.5-3.4-3.3-3.2-3.0-2.82.9-1.2
Bone: maximum moment7.112.214.23.83.8-3.8-3.6-3.63.63.73.7-3.7-3.73.73.7-3.6-3.6-3.5-3.2-3.13.0-1.6
Mean time between licks in bursts1.62.22.7-1.7-1.61.71.51.5-1.5-1.6-1.61.61.6-1.6-1.61.51.61.61.31.5-1.10.4
Mean num. licks in bursts0.20.21.60.40.4-0.4-0.1-0.20.20.10.1-0.1-0.10.10.1-0.0-0.7-0.8-0.2-0.9-0.2-1.3
Cd content in liver1.92.12.8-1.6-1.51.61.51.4-1.5-1.5-1.51.51.5-1.5-1.51.51.71.70.81.7-0.90.4
Co content in liver0.10.10.2-0.2-0.30.30.10.1-0.2-0.3-0.30.30.3-0.3-0.30.20.40.4-0.20.40.00.1
Cu content in liver0.30.42.10.60.6-0.6-0.3-0.20.30.30.3-0.3-0.30.30.3-0.2-1.0-1.10.3-1.5-0.4-1.1
Fe content in liver0.91.11.5-1.2-1.11.21.01.0-1.1-1.1-1.11.11.1-1.1-1.11.11.21.20.81.1-0.80.6
K content in liver2.62.63.51.61.7-1.6-1.9-1.81.81.71.7-1.7-1.71.71.7-1.9-1.2-1.1-1.6-0.91.90.8
Mg content in liver0.60.62.70.40.4-0.4-0.8-0.70.80.60.6-0.6-0.60.60.6-0.90.20.3-0.90.61.31.6
Mn content in liver0.30.30.50.60.6-0.6-0.5-0.50.60.60.6-0.6-0.60.60.6-0.5-0.7-0.7-0.1-0.70.3-0.1
Na content in liver0.00.00.20.10.1-0.1-0.1-0.10.10.10.1-0.1-0.10.10.1-0.1-0.2-0.20.1-0.3-0.10.4
Rb content in liver1.01.32.41.01.1-1.0-1.2-1.21.21.21.2-1.2-1.21.21.2-1.3-0.6-0.6-1.4-0.21.61.2
Se content in liver0.30.40.50.60.7-0.6-0.7-0.70.70.70.7-0.7-0.70.70.7-0.7-0.5-0.5-0.6-0.40.70.6
Sr content in liver0.60.51.8-0.4-0.40.40.70.8-0.7-0.5-0.50.50.5-0.5-0.50.8-0.3-0.41.1-0.8-1.3-1.1
Zn content in liver0.10.10.9-0.1-0.10.10.20.4-0.2-0.2-0.20.20.2-0.2-0.20.2-0.1-0.21.0-0.4-0.50.1
Bone: minimum diameter3.87.18.32.92.9-2.9-2.9-2.72.72.82.8-2.8-2.82.82.8-2.7-2.8-2.7-2.3-2.72.1-1.0
Time in familiar zone, hab. session 10.10.10.1-0.2-0.20.20.40.2-0.3-0.3-0.30.30.3-0.3-0.30.3-0.0-0.00.1-0.0-0.30.0
Time in novel zone, hab. session 10.00.00.10.10.1-0.1-0.2-0.20.20.20.2-0.2-0.20.20.2-0.20.10.1-0.10.10.2-0.0
Total zone transitions, hab. session 10.30.41.1-0.7-0.70.70.50.4-0.5-0.6-0.60.60.6-0.6-0.60.50.90.9-0.01.1-0.10.7
Total locomotion distance, hab. session 10.30.41.60.40.4-0.3-0.7-0.70.60.50.5-0.5-0.50.50.5-0.60.10.2-1.30.41.10.9
Locomotion velocity, hab. session 10.30.41.60.40.5-0.4-0.7-0.80.60.60.6-0.6-0.60.60.6-0.60.10.2-1.30.41.10.9
Time in familiar zone, hab. session 20.20.20.6-0.5-0.50.50.30.3-0.4-0.4-0.40.40.4-0.4-0.40.40.70.7-0.20.80.00.1
Time in novel zone, hab. session 20.10.10.3-0.2-0.20.20.30.3-0.2-0.2-0.20.20.2-0.2-0.20.20.10.10.60.1-0.40.2
Total zone transitions, hab. session 20.40.63.4-0.5-0.50.50.10.0-0.1-0.3-0.30.30.3-0.3-0.30.01.11.2-0.61.60.81.8
Total locomotion distance, hab. session 20.81.13.30.70.7-0.6-1.1-1.11.10.90.9-0.9-0.90.90.9-1.10.20.3-1.60.81.81.5
Locomotion velocity, hab. session 21.11.53.90.91.0-0.9-1.3-1.41.31.21.2-1.2-1.21.21.2-1.4-0.1-0.0-1.80.52.01.5
Novel to familiar place preference ratio2.62.74.41.81.8-1.8-1.5-1.51.51.61.6-1.6-1.61.61.6-1.4-2.1-2.1-1.2-2.10.9-1.4
Novelty place preference2.52.54.41.71.7-1.7-1.4-1.41.41.51.5-1.5-1.51.51.5-1.4-2.1-2.1-1.1-2.10.8-1.2
Time in novel zone, NPP test2.02.13.31.61.6-1.6-1.3-1.31.31.41.4-1.4-1.41.41.4-1.3-1.8-1.8-1.1-1.80.8-1.0
Total zone transitions, NPP test0.70.95.0-0.7-0.70.80.20.1-0.2-0.4-0.40.40.4-0.4-0.40.11.51.6-0.52.00.82.2
Total locomotion distance, NPP test0.71.06.00.20.3-0.2-0.8-0.80.70.50.5-0.5-0.50.50.5-0.80.80.9-1.51.41.72.5
Locomotion velocity, NPP test0.70.94.20.40.5-0.4-0.9-1.00.90.70.7-0.7-0.70.70.7-0.90.40.5-1.61.01.72.0
Intraocular pressure0.50.71.30.80.8-0.8-0.9-0.90.90.80.8-0.8-0.80.80.9-0.9-0.7-0.6-1.1-0.21.20.2
Delta distance traveled before/after self-admin0.40.41.8-0.5-0.50.60.40.1-0.2-0.3-0.30.30.3-0.3-0.30.21.01.1-0.21.30.31.2
Delta ambulatory time before/after self-admin1.11.22.9-1.1-1.21.21.00.7-0.7-1.0-1.01.01.0-1.0-1.00.71.51.60.51.7-0.21.4
Parametrial fat weight1.93.84.42.12.0-2.1-2.0-2.02.12.12.1-2.1-2.12.12.1-2.0-1.9-1.9-1.7-1.71.7-1.0
Pavlov. Cond. lever latency0.91.24.6-1.0-1.01.10.60.4-0.6-0.8-0.80.80.8-0.8-0.80.61.71.8-0.62.10.51.8
Pavlov. Cond. magazine entry latency2.02.65.81.71.7-1.8-1.4-1.31.41.51.5-1.5-1.51.51.5-1.3-2.2-2.3-0.7-2.40.5-1.7
Pavlov. Cond. change in total contacts0.40.42.60.50.4-0.4-0.1-0.10.10.20.2-0.2-0.20.20.2-0.0-0.9-1.00.2-1.3-0.5-1.6
Pavlov. Cond. index score3.03.86.92.12.1-2.2-1.8-1.71.81.91.9-1.9-1.91.91.9-1.7-2.5-2.5-0.9-2.60.8-1.7
Pavlov. Cond. latency score2.32.96.71.81.8-1.9-1.5-1.31.51.61.6-1.6-1.61.61.6-1.4-2.3-2.4-0.4-2.60.4-1.8
Pavlov. Cond. lever contacts0.70.82.51.00.9-1.0-0.7-0.60.70.80.8-0.8-0.80.80.8-0.7-1.3-1.30.1-1.60.0-1.0
Pavlov. Cond. magazine entry number1.72.26.2-1.5-1.51.51.01.0-1.0-1.2-1.21.21.2-1.2-1.20.92.22.30.32.5-0.02.3
Pavlov. Cond. intertrial magazine entries0.40.51.40.50.5-0.5-0.7-0.80.80.70.7-0.7-0.70.70.7-0.8-0.1-0.0-1.10.31.20.5
Pavlov. Cond. lever-magazine prob. diff.3.13.97.02.22.1-2.2-1.8-1.71.82.02.0-2.0-2.02.02.0-1.8-2.5-2.5-1.0-2.70.9-1.8
Pavlov. Cond. response bias1.82.25.81.61.5-1.6-1.1-1.01.11.31.3-1.3-1.31.31.3-1.1-2.1-2.2-0.3-2.40.2-2.1
Pavlov. Cond. lever latency0.81.13.5-0.9-0.90.81.11.4-1.2-1.0-1.01.01.0-1.0-1.01.20.30.21.9-0.3-1.7-0.4
Pavlov. Cond. magazine entry latency1.51.84.4-1.4-1.41.51.10.9-1.1-1.2-1.21.21.2-1.2-1.21.11.91.90.12.1-0.21.4
Pavlov. Cond. change in total contacts0.20.31.6-0.3-0.30.40.1-0.2-0.1-0.2-0.20.20.2-0.2-0.20.10.90.9-0.91.30.70.8
Pavlov. Cond. index score0.20.31.4-0.3-0.30.40.0-0.20.0-0.2-0.20.20.2-0.2-0.10.00.80.9-1.01.20.80.9
Pavlov. Cond. latency score0.30.31.4-0.2-0.20.3-0.1-0.30.1-0.1-0.10.10.1-0.1-0.0-0.10.80.8-1.11.20.91.0
Pavlov. Cond. lever contacts1.21.64.21.11.1-1.0-1.4-1.61.41.31.3-1.3-1.31.31.3-1.4-0.4-0.3-2.10.21.90.2
Pavlov. Cond. magazine entry number1.01.23.71.11.2-1.2-0.8-0.60.81.01.0-1.0-1.01.00.9-0.8-1.7-1.70.2-1.9-0.1-1.5
Pavlov. Cond. intertrial magazine entries1.72.22.71.61.6-1.6-1.5-1.61.71.61.6-1.6-1.61.61.5-1.6-1.5-1.4-1.3-1.11.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.41.8-0.4-0.50.50.2-0.1-0.1-0.3-0.30.30.3-0.3-0.30.21.01.0-0.91.30.71.0
Pavlov. Cond. response bias0.30.41.80.30.3-0.2-0.5-0.70.60.40.4-0.4-0.40.40.4-0.50.30.4-1.40.81.20.4
Time in closed arm before self-admin0.30.31.0-0.5-0.10.20.50.9-0.9-0.3-0.30.30.3-0.3-0.30.60.0-0.00.9-0.1-1.0-0.8
Time in closed arm after self-admin1.41.54.6-1.1-0.90.91.21.7-1.5-1.1-1.11.11.1-1.1-1.11.30.10.02.2-0.4-2.0-0.9
Time in open arm before self-admin0.10.10.6-0.1-0.50.30.1-0.10.2-0.3-0.30.30.3-0.3-0.30.10.30.30.20.20.10.8
Time in open arm after self-admin0.10.10.5-0.1-0.20.20.0-0.30.2-0.0-0.00.00.0-0.0-0.0-0.10.60.6-0.50.70.40.7
Bone: periosteal estimation2.45.06.02.42.4-2.3-2.5-2.42.42.42.4-2.4-2.42.42.4-2.4-2.0-2.0-2.2-1.72.1-0.6
Bone: periosteal perimeter3.45.69.12.62.6-2.6-2.3-2.12.22.42.4-2.4-2.42.42.4-2.2-2.9-2.9-1.2-3.01.2-1.8
Bone: post-yield work0.10.11.1-0.1-0.10.1-0.1-0.20.10.00.0-0.0-0.00.00.0-0.10.40.5-0.40.70.51.1
Progressive ratio test 1 active lever presses1.31.41.91.21.3-1.3-1.3-1.11.21.31.3-1.3-1.31.31.4-1.2-1.0-1.0-1.0-0.81.10.1
Progressive ratio test 1 breakpoint1.71.82.51.31.5-1.5-1.5-1.21.31.51.5-1.5-1.51.51.6-1.4-1.2-1.2-1.1-0.91.2-0.0
Progressive ratio test 1 inactive lever presses3.33.64.72.02.0-2.0-2.1-2.22.12.02.0-2.0-2.02.02.0-2.0-1.5-1.5-2.2-1.12.0-0.4
Progressive ratio test 2 active lever presses0.30.30.50.60.6-0.6-0.6-0.50.60.50.5-0.5-0.50.50.6-0.6-0.7-0.7-0.3-0.70.50.0
Progressive ratio test 2 breakpoint0.50.50.70.70.8-0.8-0.8-0.80.90.70.7-0.7-0.70.70.8-0.8-0.7-0.7-0.6-0.50.80.2
Progressive ratio test 2 inactive lever presses0.30.40.70.70.6-0.7-0.6-0.60.60.60.6-0.6-0.60.60.6-0.6-0.8-0.8-0.4-0.80.5-0.4
Incentive Sensitization - Responses0.10.10.20.20.4-0.3-0.3-0.10.20.30.3-0.3-0.30.30.4-0.3-0.5-0.40.0-0.40.20.2
Incentive Sensitization - Breakpoint0.10.10.20.20.3-0.3-0.2-0.10.20.20.2-0.2-0.20.20.3-0.2-0.4-0.40.1-0.40.20.1
Sum of active levers in priming session hrs 5-60.50.51.40.70.7-0.6-0.6-0.70.60.50.5-0.5-0.50.50.5-0.4-0.9-0.9-1.2-0.70.6-1.1
Progressive ratio0.50.60.9-0.8-0.90.90.80.6-0.7-0.9-0.90.90.9-0.9-0.90.80.70.70.50.6-0.60.1
Food seeking constrained by brief footshock0.20.30.9-0.4-0.30.40.60.6-0.6-0.5-0.50.50.5-0.5-0.60.60.10.10.6-0.1-0.8-0.9
Seeking ratio, punishment vs. effort0.20.20.40.50.6-0.5-0.5-0.40.40.60.6-0.6-0.60.60.5-0.5-0.3-0.3-0.4-0.20.4-0.1
Retroperitoneal fat weight5.618.322.24.64.5-4.5-4.6-4.74.64.64.6-4.6-4.64.64.6-4.5-3.8-3.7-4.5-3.24.1-0.6
Reaction time number correct1.01.54.90.30.3-0.2-0.9-1.10.90.80.8-0.8-0.80.80.8-1.11.11.3-2.02.02.22.2
Reaction time mean minus median0.20.20.8-0.2-0.20.20.40.5-0.4-0.4-0.40.40.4-0.4-0.40.5-0.1-0.20.8-0.5-0.9-0.7
Reaction time mean minus median AUC0.00.00.30.20.0-0.10.0-0.10.2-0.0-0.00.00.0-0.0-0.1-0.0-0.3-0.30.2-0.5-0.2-0.5
Reaction time num false alarms0.20.30.5-0.6-0.50.60.50.7-0.7-0.5-0.50.50.5-0.5-0.60.60.60.60.50.5-0.50.5
Reaction time num false alarms AUC0.60.91.1-1.0-1.01.00.91.0-1.0-0.9-0.90.90.9-0.9-1.00.91.01.00.80.9-0.70.8
Reaction time trials correct on left1.01.54.90.30.3-0.2-0.9-1.10.90.80.8-0.8-0.80.80.8-1.11.11.3-2.02.02.22.2
Reaction time trials on left1.11.65.00.30.4-0.2-0.9-1.21.00.80.8-0.8-0.80.80.8-1.11.11.3-2.02.12.22.2
Reaction time mean0.30.40.60.60.7-0.7-0.7-0.70.70.70.7-0.7-0.70.70.7-0.7-0.5-0.4-0.8-0.30.7-0.5
Reaction time mean AUC0.30.40.90.60.6-0.6-0.8-0.80.70.70.7-0.7-0.70.70.7-0.7-0.2-0.2-0.9-0.00.90.0
Median of all reaction times0.30.50.90.60.7-0.7-0.8-0.80.70.80.8-0.8-0.80.80.7-0.8-0.3-0.3-1.0-0.10.9-0.3
Reaction time omissions0.20.30.80.50.4-0.4-0.7-0.80.70.50.5-0.5-0.50.50.4-0.6-0.1-0.1-0.9-0.00.80.4
Reaction time false alarm rate0.91.32.9-1.0-1.01.01.21.4-1.3-1.2-1.21.21.2-1.2-1.21.30.40.31.6-0.2-1.7-0.4
Reaction time premature initiation rate1.52.02.5-1.5-1.61.61.51.4-1.4-1.6-1.61.61.6-1.6-1.61.51.41.31.11.2-1.10.4
Reaction time premature initiations1.01.44.7-1.2-1.21.30.90.7-0.8-0.9-0.90.90.9-0.9-1.00.71.81.8-0.12.20.21.6
Std. dev. reaction times0.20.30.4-0.6-0.60.60.60.6-0.6-0.6-0.60.60.6-0.6-0.60.60.60.60.50.6-0.6-0.0
Reaction time trials completed1.11.65.00.30.4-0.2-0.9-1.21.00.80.8-0.8-0.80.80.8-1.11.11.3-2.02.12.22.2
Reaction time trials AUC1.11.65.00.30.4-0.3-1.0-1.21.00.90.9-0.9-0.90.90.8-1.21.11.2-2.12.02.22.2
Run reversals in cocaine runway, females0.60.62.3-0.8-0.60.70.60.7-0.7-0.4-0.40.40.4-0.4-0.40.41.21.30.21.5-0.21.2
Run reversals in cocaine runway, males1.11.03.11.01.0-1.0-0.9-0.70.80.80.8-0.8-0.80.80.8-0.7-1.6-1.6-0.4-1.80.2-1.4
Latency to leave start box in cocaine runway0.20.20.6-0.6-0.50.50.40.5-0.5-0.5-0.50.50.5-0.5-0.40.40.70.70.40.7-0.20.2
Latency to leave start box in cocaine runway, F0.30.31.2-0.5-0.50.50.20.2-0.2-0.4-0.40.40.4-0.4-0.30.20.90.90.01.10.21.1
Latency to leave start box in cocaine runway, M0.10.10.60.00.2-0.2-0.00.2-0.10.10.1-0.1-0.10.10.2-0.0-0.3-0.30.3-0.3-0.2-0.7
Std. dev. time between licks in bursts1.21.54.30.80.9-0.8-1.3-1.31.21.11.1-1.1-1.11.11.1-1.40.20.3-1.90.92.11.7
Total sessions with >9 infusions0.30.30.7-0.6-0.50.50.40.7-0.5-0.5-0.50.50.5-0.5-0.40.50.50.50.90.4-0.60.7
Short access day 1 total inactive lever presses0.10.11.5-0.0-0.00.0-0.2-0.30.3-0.0-0.00.00.0-0.00.1-0.20.30.4-0.30.50.51.2
Short access day 10 total inactive lever presses3.43.74.62.12.1-2.1-1.9-2.02.11.91.9-1.9-1.91.91.9-2.0-2.1-2.1-1.9-1.81.8-0.9
Short access day 1 total infusions1.71.82.3-1.4-1.41.41.41.3-1.4-1.5-1.51.51.5-1.5-1.31.51.31.21.31.0-1.30.3
Short access day 10 total infusions0.50.50.80.80.9-0.9-0.8-0.60.70.70.7-0.7-0.70.70.8-0.6-0.9-0.9-0.5-0.90.4-0.5
Short access total infusions0.00.00.1-0.10.1-0.0-0.00.2-0.1-0.1-0.10.10.1-0.10.00.1-0.0-0.00.3-0.0-0.20.2
Short access day 1 locomotion0.40.50.8-0.6-0.70.60.80.7-0.6-0.7-0.70.70.7-0.7-0.80.70.30.30.9-0.0-0.9-0.6
Short access day 10 total locomotion0.30.41.0-0.4-0.40.30.50.7-0.6-0.6-0.60.60.6-0.6-0.60.7-0.2-0.31.0-0.6-1.0-1.0
Short access total locomotion0.60.61.7-0.8-0.70.60.81.0-0.8-0.9-0.90.90.9-0.9-0.90.90.30.21.3-0.1-1.1-0.4
One hour access (0.3 mA shock)1.51.82.31.31.5-1.4-1.5-1.31.41.51.5-1.5-1.51.51.5-1.5-1.1-1.1-1.2-0.81.40.5
Compulsive drug intake0.60.61.20.80.8-0.7-0.9-0.90.80.90.9-0.9-0.90.90.8-0.9-0.5-0.4-1.1-0.21.00.1
One hour access (shock baseline)0.20.30.60.50.5-0.5-0.5-0.60.60.50.5-0.5-0.50.50.6-0.6-0.3-0.3-0.4-0.20.60.8
Social response proportion0.40.40.8-0.6-0.80.80.60.3-0.4-0.7-0.70.70.7-0.7-0.70.50.90.90.10.9-0.10.2
Social responses0.00.00.2-0.2-0.20.20.00.0-0.1-0.1-0.10.10.1-0.1-0.10.10.40.4-0.10.40.00.2
Social time0.00.10.3-0.2-0.20.30.1-0.0-0.1-0.1-0.10.10.1-0.1-0.10.10.50.5-0.20.50.20.3
Soleus weight1.54.55.42.32.3-2.3-2.3-2.22.32.32.3-2.3-2.32.32.3-2.3-2.0-1.9-1.8-1.62.0-0.4
Bone: stiffness0.91.31.71.21.2-1.2-1.2-1.31.31.21.2-1.2-1.21.21.2-1.3-1.0-1.0-1.2-0.81.2-0.3
Tibialis anterior weight0.00.20.50.30.3-0.3-0.4-0.40.40.40.4-0.4-0.40.40.4-0.50.10.2-0.50.40.70.6
Time to tail flick, vehicle, before self-admin0.10.10.10.20.3-0.3-0.3-0.20.30.30.3-0.3-0.30.30.3-0.3-0.1-0.1-0.2-0.10.30.1
Time to tail flick, vehicle, after self-admin2.32.43.0-1.7-1.61.61.61.7-1.6-1.6-1.61.61.6-1.6-1.61.61.61.51.71.3-1.50.8
Time to tail flick, test, before self-admin0.00.00.20.10.0-0.10.1-0.00.1-0.1-0.10.10.1-0.1-0.1-0.0-0.4-0.40.1-0.40.0-0.4
Time to tail flick, test, after self-admin0.30.30.6-0.5-0.70.60.50.4-0.4-0.8-0.80.80.8-0.8-0.80.60.40.30.50.1-0.50.1
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.5-0.70.60.50.2-0.2-0.6-0.60.60.6-0.6-0.60.40.80.80.10.8-0.00.8
Delta time to tail flick, test, before/after SA0.60.50.8-0.7-0.80.80.70.7-0.8-0.8-0.80.80.8-0.8-0.80.90.50.50.70.2-0.9-0.2
Tibia length9.125.735.25.55.5-5.6-4.9-4.75.05.25.2-5.2-5.25.25.3-4.9-5.9-5.9-3.2-5.83.1-3.3
Ambulatory time before self-admin2.72.83.71.81.8-1.8-1.7-1.61.51.71.7-1.7-1.71.71.7-1.5-1.9-1.9-1.6-1.91.1-1.4
Ambulatory time after self-admin0.50.61.10.80.8-0.7-0.8-0.90.80.80.8-0.8-0.80.80.8-0.8-0.4-0.4-1.0-0.20.9-0.0
Bone: tissue strength1.71.72.51.31.3-1.3-1.5-1.41.41.41.4-1.4-1.41.41.4-1.5-0.9-0.8-1.5-0.61.60.0
Total heroin consumption0.20.22.00.40.1-0.1-0.0-0.30.1-0.0-0.00.00.0-0.0-0.00.1-0.5-0.6-0.4-0.8-0.2-1.4
Bone: trabecular number0.00.00.30.10.1-0.1-0.1-0.10.10.10.1-0.1-0.10.10.1-0.1-0.1-0.10.1-0.00.10.5
Bone: trabecular spacing0.71.03.50.50.5-0.4-1.0-1.10.90.70.7-0.7-0.70.70.7-1.00.50.6-1.91.11.91.4
Bone: trabecular thickness0.50.62.60.60.6-0.6-0.2-0.20.20.40.4-0.4-0.40.40.4-0.2-1.2-1.30.3-1.6-0.5-1.5
Bone: trabecular tissue density0.91.31.5-1.2-1.21.21.21.2-1.2-1.2-1.21.21.2-1.2-1.21.21.11.11.01.0-1.00.0
Water consumed over 24 hours0.20.32.4-0.1-0.10.10.30.4-0.3-0.3-0.30.30.3-0.3-0.30.4-0.3-0.30.7-0.7-0.8-1.6
Number of responses in last shaping day1.31.32.81.41.0-1.0-1.2-1.71.61.01.0-1.0-1.01.01.1-1.2-1.0-0.9-1.5-0.91.40.1