Hub : Genes

LOC103693474

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	LOC103693474	0.07	0.03	2.8e-05	0.06	0.04	0.03	0.01	1.7e-06	4.6e-05	3.9e-04	1.3e-02
2	PL	gene expression	LOC103693474	0.11	0.05	1.3e-07	0.05	0.07	0.06	0.04	3.4e-06	6.1e-08	2.1e-07	2.2e-05
3	BLA	gene expression	LOC103693474	0.21	0.08	8.8e-08	0.16	0.14	0.1	0.15	8.5e-09	1.1e-07	2.9e-06	1.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.0	0.0	0.0	-0.1	-0.0	0.0
Area under the delay curve	2.6	2.8	5.2	-0.9	1.5	-2.3
BMI with tail	0.2	0.8	1.8	-0.7	-0.3	1.4
BMI without tail	0.1	0.2	0.4	-0.6	0.4	-0.5
Body weight	0.1	0.4	0.9	-1.0	0.3	0.3
Weight adjusted by age	0.2	0.3	0.4	-0.6	-0.2	-0.7
Bone surface	1.9	3.3	6.5	2.6	-1.7	0.6
Bone volume	0.9	1.6	3.6	1.9	-1.1	0.0
Breakpoint value in progressive ratio session	1.6	1.8	2.6	-1.0	1.6	-1.3
Number of licking bursts	0.5	0.6	0.8	0.9	0.5	-0.9
Context. condit. distance diff. score	0.1	0.2	0.3	-0.4	-0.0	0.5
Locomotion velocity, session 1	0.3	0.3	0.5	0.5	0.5	-0.7
Locomotion distance, session 1	0.0	0.0	0.1	0.3	-0.2	0.0
Locomotion velocity, session 2	0.8	0.9	1.5	1.2	-0.7	0.9
Locomotion distance, session 2	1.2	1.6	2.5	1.6	-1.0	1.2
Locomotion velocity, session 3	0.1	0.2	0.2	-0.5	0.3	-0.3
Locomotion distance, session 3	2.1	2.3	3.4	1.4	-1.3	1.8
Stereotopy head waving bouts, day 3	1.2	1.5	2.2	-1.5	1.2	-0.9
Stereotopy head waving duration, day 3	0.0	0.0	0.0	-0.1	0.2	0.0
Locomotion velocity, session 7	3.7	4.0	4.9	2.0	-1.8	2.2
Locomotion distance, session 7	6.3	8.0	9.4	2.8	-2.6	3.1
Stereotopy head waving bouts, day 7	1.0	1.1	2.2	-1.5	0.8	-0.7
Stereotopy head waving duration, day 7	0.7	0.8	1.6	-1.3	0.8	-0.6
Locomotion velocity, session 8	1.0	1.2	1.9	1.4	-0.6	1.1
Locomotion distance, session 8	1.8	2.7	3.6	1.4	-1.6	1.9
Degree of sensitization distance	0.8	0.8	1.1	0.9	-1.1	0.7
Degree of sensitization stereotypy	0.7	0.8	1.7	-1.3	0.7	-0.5
Conditioned locomotion	0.1	0.1	0.2	-0.0	-0.3	0.5
Cocaine response after cond. corrected	1.4	1.6	2.2	-1.3	1.5	-1.0
Cocaine response after cond. not corrected	0.7	0.7	1.2	-0.7	1.1	-0.7
Cocaine response before conditioning	1.6	2.0	2.4	1.5	-1.4	1.3
Saline control response	0.2	0.3	0.7	0.3	-0.9	0.2
Bone: connectivity density	0.4	0.6	0.8	0.6	-0.9	0.8
Bone: cortical apparent density	3.1	4.1	5.7	-2.4	2.0	-1.6
Bone: cortical area	2.8	4.2	6.4	1.1	-2.2	2.5
Bone: cortical porosity	0.4	0.4	0.6	0.8	-0.8	0.4
Bone: cortical porosity	0.6	0.7	1.1	1.1	-0.9	0.5
Bone: cortical thickness	2.5	4.1	11.3	-3.4	0.7	0.6
Bone: cortical thickness	0.7	0.8	2.1	-1.5	0.3	0.5
Bone: cortical tissue density	3.4	4.5	5.9	-2.4	2.1	-1.8
Condit. Reinf. active minus inactive responses	1.0	1.1	1.7	0.3	-1.3	1.2
Condit. Reinf. active-inactive response ratio	1.4	1.5	2.2	0.3	-1.5	1.5
Condit. Reinf. active responses	0.2	0.3	0.4	-0.2	-0.6	0.6
Condit. Reinf. inactive responses	0.2	0.3	0.3	-0.4	0.6	-0.6
Incentive salience index mean	0.2	0.2	0.4	-0.2	-0.6	0.5
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.5	-0.0	-0.2
Condit. Reinf. active minus inactive responses	0.8	1.0	1.7	0.6	-0.9	1.3
Condit. Reinf. active-inactive response ratio	0.7	0.8	1.1	1.0	-0.8	0.8
Condit. Reinf. active responses	1.1	1.5	2.5	0.8	-1.1	1.6
Condit. Reinf. inactive responses	0.6	0.8	1.5	0.2	-0.9	1.2
Condit. Reinf. lever presses	3.4	4.7	4.8	2.1	-2.2	2.2
Condit. Reinf. lever reinforcers received	1.7	2.4	3.5	1.2	-1.5	1.9
Conditioned reinforcement - actives	0.2	0.2	0.3	0.4	-0.1	0.5
Conditioned reinforcement - inactives	4.3	4.9	6.3	1.8	-2.3	2.5
Conditioned locomotion	0.1	0.1	0.2	0.5	-0.4	0.3
Patch foraging indifference point 0 sec	1.0	1.6	2.3	0.7	-1.4	1.5
Patch foraging indifference point AUC	1.3	1.4	2.6	1.6	-1.2	0.6
Delay disc. indifference point, 0s delay	0.8	0.8	1.0	-1.0	0.8	-0.9
Delay disc. indifference point, 16s delay	0.3	0.3	0.8	0.1	0.2	-0.9
Delay disc. indifference point, 2s delay	5.0	5.5	10.1	-1.3	2.2	-3.2
Delay disc. indifference point, 24s delay	0.3	0.3	0.6	0.4	0.2	-0.8
Delay disc. indifference point, 4s delay	3.2	3.4	5.0	-1.3	1.9	-2.2
Delay disc. indifference point, 8s delay	2.3	2.4	4.2	-1.0	1.4	-2.0
Indifference point function ln k	0.4	0.6	1.5	-1.2	0.1	0.5
Indifference point function log k	0.4	0.6	1.5	-1.2	0.1	0.5
Patch foraging total patch changes 0 sec	1.0	1.6	2.4	0.7	-1.4	1.6
Patch foraging total patch changes 12 sec	3.3	4.2	4.6	2.0	-2.1	2.0
Patch foraging total patch changes 18 sec	0.4	0.6	0.7	0.6	-0.8	0.9
Patch foraging total patch changes 24 sec	4.5	5.5	5.9	2.2	-2.4	2.4
Patch foraging total patch changes 6 sec	1.8	2.6	4.0	1.3	-2.0	1.5
Patch foraging time to switch 0 sec	0.2	0.3	0.5	0.1	0.7	-0.6
Patch foraging water rate 0 sec	0.2	0.3	0.6	0.2	-0.8	0.5
Patch foraging water rate 12 sec	0.8	1.2	2.8	-1.7	0.8	-0.5
Patch foraging water rate 18 sec	0.4	0.6	0.8	-0.6	-0.7	0.9
Patch foraging water rate 24 sec	1.0	1.4	3.0	-0.5	-1.0	1.7
Patch foraging water rate 6 sec	1.0	1.5	2.8	-1.7	1.1	-0.6
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.3	-0.0	-0.5	0.1
Distance traveled before self-admin	1.1	1.2	1.7	-1.1	1.3	-0.8
Distance traveled after self-admin	0.0	0.0	0.1	0.1	-0.0	-0.3
Extensor digitorum longus weight	0.0	0.1	0.3	0.2	0.4	0.5
Bone: elastic displacement	1.5	1.7	4.4	-2.1	0.8	-0.3
Bone: elastic work	0.7	0.9	1.3	-1.1	-0.6	1.0
Bone: endosteal estimation	14.5	31.6	50.9	7.1	-5.3	3.9
Bone: endosteal perimeter	9.9	20.5	37.8	6.1	-4.2	2.5
Epididymis fat weight	0.0	0.1	0.2	0.1	-0.5	-0.0
Delta time in closed arm before/after self-admin	4.4	4.3	5.8	2.4	-1.8	2.0
Delta time in open arm before/after self-admin	4.1	4.0	4.5	-2.1	1.7	-2.1
Diff in mean of infusions in LGA sessions	0.7	0.8	0.9	-0.9	0.9	-0.8
Delay discount exponential model param	3.3	3.5	6.3	1.0	-1.7	2.5
Extinction: sum of active levers before priming	0.5	0.5	0.9	0.8	-0.3	1.0
Active lever presses in extinction session 6	0.3	0.3	0.8	-0.1	0.4	-0.9
Bone: final force	4.9	7.9	11.1	1.9	-3.0	3.3
Bone: final moment	3.8	6.2	9.7	1.4	-2.6	3.1
Food consumed during 24 hour testing period	0.1	0.1	0.3	0.6	-0.2	-0.2
Glucose	0.4	0.5	0.8	0.9	-0.6	0.7
Heart weight	2.8	4.0	5.4	1.6	-2.3	2.0
Delay discount hyperbolic model param	3.4	3.6	6.5	1.0	-1.8	2.5
Intermittent access intake day 1-15 change	2.3	2.3	2.5	-1.4	1.5	-1.6
Intermittent access intake escalation	1.8	1.8	2.2	-1.3	1.2	-1.5
Intermittent access intake escalation 2	4.5	4.4	5.8	-1.9	2.0	-2.4
Intermitt. access day 1 inactive lever presses	3.2	3.5	6.2	1.0	-1.8	2.5
Intermitt. access day 15 inactive lever presses	0.7	0.8	1.1	1.0	-0.9	0.7
Intermitt. access escalation Index	0.9	0.8	0.9	1.0	-0.8	0.9
Intermittent access day 1 total infusions	2.2	2.6	2.9	1.4	-1.7	1.6
Intermittent access day 15 total infusions	0.3	0.4	0.8	0.5	-0.9	0.4
Intermittent access terminal intake (last 3 days)	0.3	0.4	0.5	0.6	-0.7	0.5
Intermittent access total infusions	2.2	2.5	3.1	1.5	-1.8	1.5
Intermittent access day 1 locomotion	1.9	2.0	2.3	1.4	-1.5	1.4
Intermittent access day 15 total locomotion	0.5	0.6	0.9	0.3	-1.0	0.8
Intermittent access total locomotion	1.7	2.0	2.7	1.3	-1.6	1.2
Intermittent access standard deviation	0.0	0.0	0.1	-0.3	-0.0	-0.2
Left kidney weight	0.1	0.3	0.4	-0.7	0.3	-0.6
Right kidney weight	0.2	0.7	1.2	-1.1	0.5	-0.8
Cocaine induced anxiety	0.4	0.5	0.7	0.7	-0.6	0.8
Post-drug Anxiety	1.6	1.7	2.5	1.6	-1.1	1.2
Baseline Anxiety	0.1	0.1	0.2	0.3	0.4	-0.4
Tail length	0.4	1.3	3.5	0.2	0.5	-1.9
Length with tail	0.3	1.1	1.9	-0.8	0.9	-1.4
Length without tail	0.2	0.5	1.0	-1.0	0.6	0.3
Times rat made contact with spout	3.3	3.8	7.0	-1.1	1.8	-2.6
Lifetime Intake	3.1	3.5	4.1	1.7	-2.0	1.9
Liver weight, left	0.1	0.1	0.2	-0.3	-0.2	0.4
Liver weight, right	0.3	0.5	1.3	-0.3	-0.5	1.1
Locomotor activity	1.2	1.9	2.2	1.5	-1.3	1.4
Locomotor testing distance	1.2	1.9	2.8	1.0	-1.4	1.7
Locomotor testing rearing	0.1	0.1	0.2	0.2	-0.5	0.3
Locomotion in novel chamber	0.1	0.1	0.2	-0.1	0.2	-0.4
Locomotion in novel chamber post-restriction	0.3	0.4	0.4	0.5	-0.6	0.6
Fecal boli incidents, locomotor time 1	0.3	0.4	0.7	0.9	-0.5	0.4
Change in fecal boli incidents, locomotor task	0.5	0.4	0.9	-1.0	0.5	-0.4
Time >=10cm from walls, locomotor time 1	0.8	0.9	1.1	1.0	-0.7	1.1
Bouts of movement, locomotor time 1	0.2	0.2	0.4	0.6	-0.4	0.4
Total resting periods, locomotor time 1	0.1	0.1	0.2	0.5	0.1	0.0
Rest time, locomotor task time 1	0.3	0.4	0.5	-0.7	0.7	-0.3
Distance moved, locomotor task time 1	0.4	0.4	0.6	-0.6	0.6	-0.8
Vertical activity count, locomotor time 1	2.6	2.8	4.1	1.6	-2.0	1.3
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.0	-0.0	0.1	-0.0
Bouts of movement, locomotor time 2	1.3	1.4	2.0	-0.9	1.4	-1.2
Total resting periods, locomotor time 2	0.8	0.9	1.3	-0.6	1.1	-1.0
Rest time, locomotor task time 2	0.1	0.1	0.2	0.2	-0.0	0.4
Distance moved, locomotor task time 2	0.1	0.1	0.2	-0.2	0.2	-0.4
Vertical activity count, locomotor time 2	0.1	0.1	0.4	0.0	-0.6	0.1
Light reinforcement 1	1.0	1.8	2.5	0.7	-1.6	1.5
Light reinforcement 2	2.4	3.2	3.8	2.0	-1.9	1.6
Bone: marrow area	14.3	31.1	50.0	7.1	-5.3	3.9
Bone: maximum diameter	8.9	16.4	21.8	4.7	-4.0	3.4
Bone: maximum force	5.6	9.6	11.6	2.5	-3.3	3.4
Bone: maximum moment	4.3	7.4	9.9	2.0	-2.9	3.1
Mean time between licks in bursts	0.4	0.6	0.9	1.0	-0.7	0.7
Mean num. licks in bursts	0.6	0.7	1.8	-1.4	0.3	-0.4
Cd content in liver	0.5	0.5	1.2	0.1	-0.5	1.1
Co content in liver	1.1	1.2	1.3	-1.1	1.2	-1.1
Cu content in liver	0.0	0.0	0.0	-0.0	-0.2	-0.0
Fe content in liver	1.1	1.3	2.3	0.6	-1.2	1.5
K content in liver	1.0	1.0	1.9	-0.4	1.4	-1.0
Mg content in liver	0.3	0.3	0.5	0.1	0.5	-0.7
Mn content in liver	0.1	0.1	0.3	0.5	-0.4	-0.1
Na content in liver	0.4	0.4	0.6	0.5	0.8	-0.6
Rb content in liver	0.2	0.3	0.4	0.6	-0.6	0.3
Se content in liver	1.0	1.3	2.6	-0.3	1.0	-1.6
Sr content in liver	0.9	0.8	1.7	1.3	-0.7	0.4
Zn content in liver	0.2	0.2	0.3	-0.5	0.5	-0.2
Bone: minimum diameter	4.9	9.2	12.3	3.5	-3.2	2.3
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.2	-0.3	0.4
Time in novel zone, hab. session 1	0.1	0.1	0.2	-0.1	0.1	-0.4
Total zone transitions, hab. session 1	0.2	0.3	0.7	-0.3	0.2	-0.8
Total locomotion distance, hab. session 1	0.2	0.4	0.9	0.2	-1.0	0.3
Locomotion velocity, hab. session 1	0.2	0.3	0.6	0.4	-0.8	0.4
Time in familiar zone, hab. session 2	0.9	0.9	1.1	-1.0	1.0	-0.9
Time in novel zone, hab. session 2	2.7	2.7	3.9	1.2	-1.6	2.0
Total zone transitions, hab. session 2	0.3	0.4	0.7	0.9	-0.5	0.4
Total locomotion distance, hab. session 2	0.1	0.2	0.2	0.4	-0.5	0.4
Locomotion velocity, hab. session 2	0.1	0.1	0.2	0.4	-0.3	0.2
Novel to familiar place preference ratio	0.2	0.2	0.2	-0.4	0.3	-0.5
Novelty place preference	0.0	0.0	0.0	-0.2	0.1	-0.2
Time in novel zone, NPP test	0.0	0.0	0.0	-0.0	-0.2	0.1
Total zone transitions, NPP test	0.4	0.5	0.9	0.9	-0.6	0.5
Total locomotion distance, NPP test	0.8	1.1	1.4	0.8	-1.2	1.1
Locomotion velocity, NPP test	0.2	0.3	0.4	0.4	-0.6	0.5
Intraocular pressure	1.0	1.4	2.1	1.4	-1.0	1.0
Delta distance traveled before/after self-admin	1.4	1.5	2.7	1.1	-1.6	0.8
Delta ambulatory time before/after self-admin	1.1	1.2	1.9	1.1	-1.4	0.6
Parametrial fat weight	0.5	1.0	1.5	1.2	-1.0	0.7
Pavlov. Cond. lever latency	1.5	1.9	2.2	1.5	-1.2	1.5
Pavlov. Cond. magazine entry latency	2.6	3.4	5.3	-2.3	1.5	-1.6
Pavlov. Cond. change in total contacts	0.6	0.7	1.3	-1.2	0.7	-0.5
Pavlov. Cond. index score	2.1	2.6	3.6	-1.9	1.4	-1.5
Pavlov. Cond. latency score	2.8	3.6	4.5	-2.1	1.7	-1.9
Pavlov. Cond. lever contacts	1.4	1.6	2.4	-1.6	1.1	-1.1
Pavlov. Cond. magazine entry number	2.9	3.6	6.1	2.5	-1.5	1.6
Pavlov. Cond. intertrial magazine entries	0.4	0.5	0.6	0.8	-0.7	0.6
Pavlov. Cond. lever-magazine prob. diff.	1.7	2.1	2.9	-1.7	1.2	-1.3
Pavlov. Cond. response bias	1.2	1.4	3.0	-1.7	0.8	-0.8
Pavlov. Cond. lever latency	2.2	3.0	3.8	-1.5	1.7	-1.9
Pavlov. Cond. magazine entry latency	4.7	5.5	7.0	2.2	-2.1	2.6
Pavlov. Cond. change in total contacts	4.7	6.5	9.1	2.3	-2.2	3.0
Pavlov. Cond. index score	4.3	5.6	6.8	2.3	-2.2	2.6
Pavlov. Cond. latency score	4.8	6.0	7.3	2.4	-2.2	2.7
Pavlov. Cond. lever contacts	1.7	2.3	2.5	1.4	-1.5	1.6
Pavlov. Cond. magazine entry number	5.6	6.8	9.5	-2.4	2.3	-3.1
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.1	-0.4	-0.4
Pavlov. Cond. lever-magazine prob. diff.	4.1	5.2	6.5	2.2	-2.1	2.6
Pavlov. Cond. response bias	2.6	3.5	4.6	1.7	-1.8	2.1
Time in closed arm before self-admin	0.0	0.0	0.1	0.1	-0.3	-0.1
Time in closed arm after self-admin	2.5	2.6	2.8	1.7	-1.6	1.6
Time in open arm before self-admin	0.2	0.2	0.5	-0.2	0.7	-0.4
Time in open arm after self-admin	0.2	0.3	0.6	-0.0	0.4	-0.8
Bone: periosteal estimation	10.7	22.1	27.3	5.2	-4.8	4.0
Bone: periosteal perimeter	4.7	7.8	11.3	3.4	-2.8	2.1
Bone: post-yield work	4.3	5.9	7.8	2.8	-2.6	1.8
Progressive ratio test 1 active lever presses	0.6	0.6	0.8	0.8	-0.9	0.7
Progressive ratio test 1 breakpoint	0.6	0.6	0.7	0.7	-0.9	0.8
Progressive ratio test 1 inactive lever presses	4.2	4.6	6.7	1.6	-2.1	2.6
Progressive ratio test 2 active lever presses	0.7	0.8	1.1	1.1	-0.9	0.6
Progressive ratio test 2 breakpoint	0.7	0.8	1.3	1.1	-0.9	0.6
Progressive ratio test 2 inactive lever presses	2.1	2.4	2.7	1.5	-1.5	1.6
Incentive Sensitization - Responses	0.1	0.1	0.2	0.5	-0.1	-0.1
Incentive Sensitization - Breakpoint	0.1	0.1	0.1	0.3	0.1	-0.3
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.5	-0.7	0.5	-0.5
Progressive ratio	0.3	0.3	0.8	0.9	-0.2	0.4
Food seeking constrained by brief footshock	0.9	1.1	1.7	-1.0	1.3	-0.8
Seeking ratio, punishment vs. effort	1.0	1.3	1.7	-1.3	1.1	-1.0
Retroperitoneal fat weight	0.3	1.0	2.2	0.4	-1.5	0.8
Reaction time number correct	0.2	0.3	0.5	0.1	-0.6	0.7
Reaction time mean minus median	0.2	0.2	0.5	-0.4	-0.7	-0.2
Reaction time mean minus median AUC	0.7	0.9	1.8	0.1	-1.4	0.9
Reaction time num false alarms	0.0	0.0	0.1	0.1	-0.1	0.2
Reaction time num false alarms AUC	0.0	0.0	0.1	0.1	0.2	-0.1
Reaction time trials correct on left	0.2	0.3	0.5	0.1	-0.6	0.7
Reaction time trials on left	0.3	0.4	0.6	0.1	-0.7	0.8
Reaction time mean	0.5	0.7	1.7	0.4	-1.3	0.5
Reaction time mean AUC	1.1	1.5	2.7	0.7	-1.6	1.1
Median of all reaction times	0.8	1.1	2.1	0.7	-1.4	0.9
Reaction time omissions	0.9	1.2	2.0	0.7	-1.4	1.1
Reaction time false alarm rate	0.2	0.3	0.5	-0.2	0.7	-0.7
Reaction time premature initiation rate	7.2	9.6	12.0	-2.8	3.0	-3.5
Reaction time premature initiations	3.2	4.6	5.5	-2.1	2.0	-2.3
Std. dev. reaction times	0.1	0.1	0.4	-0.2	-0.6	-0.1
Reaction time trials completed	0.3	0.4	0.6	0.1	-0.7	0.8
Reaction time trials AUC	0.4	0.5	0.8	0.3	-0.8	0.9
Run reversals in cocaine runway, females	1.0	1.0	1.2	-1.0	1.1	-0.8
Run reversals in cocaine runway, males	0.0	0.0	0.1	-0.3	0.1	-0.1
Latency to leave start box in cocaine runway	0.2	0.2	0.6	-0.8	-0.1	0.2
Latency to leave start box in cocaine runway, F	1.0	1.1	2.5	-1.6	0.7	-0.6
Latency to leave start box in cocaine runway, M	0.8	0.7	1.0	0.6	-1.0	1.0
Std. dev. time between licks in bursts	2.2	2.7	3.3	1.7	-1.4	1.8
Total sessions with >9 infusions	0.1	0.1	0.2	-0.1	-0.4	0.4
Short access day 1 total inactive lever presses	3.9	4.3	5.5	1.7	-2.2	2.3
Short access day 10 total inactive lever presses	2.6	2.9	4.3	1.4	-1.6	2.1
Short access day 1 total infusions	1.3	1.4	2.6	0.7	-1.0	1.6
Short access day 10 total infusions	1.7	1.9	2.6	1.0	-1.6	1.4
Short access total infusions	3.0	3.4	3.9	1.6	-2.0	2.0
Short access day 1 locomotion	0.4	0.4	0.7	-0.0	-0.8	0.7
Short access day 10 total locomotion	0.5	0.6	1.0	1.0	-0.8	0.4
Short access total locomotion	0.1	0.1	0.3	0.1	-0.5	0.4
One hour access (0.3 mA shock)	1.0	1.2	1.2	1.1	-1.1	1.0
Compulsive drug intake	0.7	0.7	1.2	0.7	-0.6	1.1
One hour access (shock baseline)	0.1	0.1	0.2	0.5	-0.3	-0.0
Social response proportion	0.5	0.5	1.2	-1.1	0.2	-0.6
Social responses	0.4	0.5	1.5	-1.2	-0.2	0.1
Social time	0.3	0.5	1.2	0.1	-1.1	0.3
Soleus weight	0.3	1.0	1.8	1.3	-0.6	0.8
Bone: stiffness	5.5	8.7	9.2	2.8	-3.0	3.0
Tibialis anterior weight	0.0	0.0	0.1	-0.2	0.3	0.1
Time to tail flick, vehicle, before self-admin	0.5	0.5	0.6	0.8	-0.7	0.6
Time to tail flick, vehicle, after self-admin	1.1	1.2	1.7	-0.8	1.1	-1.3
Time to tail flick, test, before self-admin	1.5	1.4	2.4	-0.3	1.3	-1.5
Time to tail flick, test, after self-admin	0.8	0.8	1.5	-0.5	1.2	-0.8
Delta time to tail flick, vehicle, before/after SA	2.0	2.0	2.2	-1.4	1.3	-1.5
Delta time to tail flick, test, before/after SA	0.3	0.2	0.7	0.2	0.0	0.8
Tibia length	0.3	0.9	2.2	-1.5	0.8	-0.2
Ambulatory time before self-admin	1.6	1.6	2.0	-1.4	1.4	-0.9
Ambulatory time after self-admin	0.1	0.1	0.3	-0.1	0.3	-0.5
Bone: tissue strength	1.0	1.0	1.9	-0.4	-1.0	1.4
Total heroin consumption	0.3	0.3	0.8	0.3	0.9	-0.3
Bone: trabecular number	0.1	0.2	0.2	-0.4	0.4	-0.3
Bone: trabecular spacing	0.0	0.0	0.1	-0.1	-0.1	0.3
Bone: trabecular thickness	0.1	0.1	0.1	0.3	0.1	-0.3
Bone: trabecular tissue density	0.2	0.3	0.8	0.1	0.2	-0.9
Water consumed over 24 hours	0.2	0.3	0.8	0.1	0.2	-0.9
Number of responses in last shaping day	1.2	1.2	2.2	0.9	-1.5	0.8