LOC103693090

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC103693090 0.18 0.11 0.0e+00 0.18 0.22 0.22 0.22 1.8e-14 1.5e-17 1.6e-17 1.0e-17
2 PL alternative polyA XR_595877.4 0.04 0.04 1.5e-04 0.03 0.04 0.04 0.03 7.6e-04 5.4e-05 1.9e-05 2.3e-04
3 PL alternative polyA XR_005493371.2 0.04 0.04 1.9e-04 0.03 0.04 0.04 0.03 8.6e-04 6.5e-05 2.3e-05 2.7e-04
4 PL isoform ratio XR_595877.4 0.04 0.04 6.1e-04 0.03 0.03 0.03 0.03 8.8e-04 2.3e-04 2.2e-04 6.8e-04
5 PL isoform ratio XR_005493371.2 0.04 0.03 5.9e-04 0.02 0.03 0.01 0.03 4.3e-03 2.4e-04 2.7e-02 7.5e-04
6 IL gene expression LOC103693090 0.3 0.14 1.6e-09 0.23 0.37 0.31 0.34 2.5e-06 6.4e-10 2.6e-08 4.1e-09
7 Adipose gene expression LOC103693090 0.25 0.12 0.0e+00 0.33 0.32 0.32 0.33 2.1e-37 9.4e-37 1.4e-36 1.6e-37
8 PL gene expression LOC103693090 0.18 0.09 0.0e+00 0.26 0.28 0.27 0.27 5.1e-28 4.0e-31 2.9e-29 9.9e-30
9 pVTA alternative polyA XR_005493371.2 0.04 0.03 3.2e-04 0.03 0.05 0.04 0.05 1.8e-03 1.4e-04 1.4e-04 9.4e-05
10 pVTA alternative polyA XR_595877.4 0.04 0.04 2.8e-04 0.03 0.05 0.05 0.05 1.6e-03 1.3e-04 1.3e-04 8.6e-05
11 pVTA isoform ratio XR_595877.4 0.03 0.03 2.9e-03 0.02 0.03 0.03 0.03 1.1e-02 1.4e-03 1.2e-03 1.2e-03
12 NAcc gene expression LOC103693090 0.26 0.12 0.0e+00 0.36 0.38 0.37 0.37 4.2e-56 1.6e-60 2.8e-58 3.8e-59
13 Brain gene expression LOC103693090 0.24 0.11 0.0e+00 0.35 0.35 0.35 0.36 2.1e-33 3.5e-34 3.2e-34 1.4e-34
14 BLA gene expression LOC103693090 0.24 0.13 5.6e-17 0.24 0.28 0.27 0.27 6.1e-13 3.1e-15 1.1e-14 1.4e-14
15 OFC gene expression LOC103693090 0.38 0.15 4.4e-12 0.42 0.48 0.46 0.5 2.5e-11 6.9e-13 1.6e-12 9.9e-14
16 LHb gene expression LOC103693090 0.34 0.15 1.7e-07 0.15 0.21 0.19 0.19 2.5e-04 1.3e-05 3.1e-05 3.2e-05
17 IC gene expression LOC103693090 0.16 0.1 2.7e-07 0.11 0.14 0.11 0.15 1.9e-05 1.2e-06 3.1e-05 5.9e-07
18 IL alternative polyA XR_005493371.2 0.43 0.2 3.2e-03 0.16 0.1 0.12 0.14 1.2e-04 2.7e-03 7.1e-04 3.3e-04
19 IL alternative polyA XR_595877.4 0.4 0.2 4.3e-03 0.15 0.09 0.11 0.13 1.7e-04 4.3e-03 1.2e-03 4.4e-04
20 RMTg isoform ratio XR_595877.4 0.38 0.26 3.2e-03 0.04 0.05 0.05 0.06 2.6e-02 1.8e-02 1.6e-02 1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.81.32.21.2-0.40.4-0.61.31.41.31.41.3-1.3-1.31.40.91.41.01.41.00.9-0.91.5
Area under the delay curve0.30.41.5-0.6-0.10.1-0.3-0.1-0.6-0.7-0.4-0.60.60.6-0.6-0.6-0.7-0.6-0.7-0.50.7-0.7-1.2
BMI with tail1.86.211.1-2.60.4-0.40.3-2.6-3.0-2.1-3.1-3.03.03.0-3.2-2.5-3.3-2.3-3.3-1.7-1.41.4-3.1
BMI without tail1.34.17.4-1.90.5-0.40.4-2.2-2.4-1.6-2.5-2.42.42.4-2.7-2.2-2.7-2.0-2.7-1.0-1.51.5-2.3
Body weight5.624.431.4-5.53.6-3.63.7-5.2-5.6-5.2-5.5-5.45.45.4-5.5-5.2-5.5-5.1-5.5-4.9-3.53.5-5.2
Weight adjusted by age2.23.44.7-2.01.4-1.41.4-1.9-2.2-2.0-2.1-2.02.02.0-2.1-2.0-2.2-2.0-2.1-1.7-0.80.8-2.2
Bone surface0.20.42.1-0.71.4-1.41.1-0.2-0.3-0.6-0.2-0.30.30.3-0.1-0.6-0.2-0.5-0.1-1.0-0.00.00.0
Bone volume0.10.10.50.10.7-0.70.30.20.20.20.30.3-0.3-0.30.30.20.30.30.3-0.10.1-0.10.6
Breakpoint value in progressive ratio session0.10.10.50.4-0.70.7-0.60.20.20.30.20.3-0.3-0.30.10.30.10.30.10.40.1-0.10.0
Number of licking bursts1.32.24.1-1.42.0-2.02.0-1.5-1.4-1.8-1.3-1.01.01.0-1.2-1.5-1.2-1.5-1.1-1.7-1.51.5-1.0
Context. condit. distance diff. score0.30.41.20.6-1.11.1-1.00.60.60.30.50.4-0.4-0.40.50.80.50.80.50.80.2-0.20.1
Locomotion velocity, session 11.01.11.61.2-1.01.0-0.71.11.31.11.21.1-1.1-1.11.21.01.20.91.21.30.6-0.61.0
Locomotion distance, session 10.40.50.70.8-0.40.4-0.30.80.80.90.80.8-0.8-0.80.80.30.80.30.80.60.8-0.80.7
Locomotion velocity, session 24.75.58.52.7-1.61.6-1.12.42.82.12.72.9-2.9-2.92.81.92.91.82.92.21.3-1.32.4
Locomotion distance, session 22.94.15.82.2-1.71.7-1.52.42.21.92.32.3-2.3-2.32.21.32.11.22.21.72.3-2.31.5
Locomotion velocity, session 30.20.31.10.3-0.20.2-0.10.70.40.00.60.6-0.6-0.60.60.40.50.20.50.01.0-1.0-0.1
Locomotion distance, session 30.10.10.3-0.00.1-0.10.10.1-0.1-0.2-0.0-0.00.00.0-0.1-0.3-0.1-0.5-0.1-0.00.5-0.5-0.5
Stereotopy head waving bouts, day 31.61.84.71.7-2.12.2-2.10.61.01.40.71.1-1.1-1.10.61.60.71.70.62.10.1-0.10.9
Stereotopy head waving duration, day 31.51.85.51.5-2.32.3-2.30.60.91.40.61.0-1.0-1.00.51.50.61.70.51.90.3-0.30.7
Locomotion velocity, session 70.90.93.6-1.01.1-1.21.5-1.0-1.0-1.9-0.8-0.20.20.2-0.6-0.5-0.6-0.6-0.5-1.7-0.70.7-1.1
Locomotion distance, session 70.20.30.90.3-0.40.4-0.10.60.4-0.40.60.7-0.7-0.70.60.30.50.10.6-0.30.9-0.9-0.4
Stereotopy head waving bouts, day 70.91.02.3-0.7-0.60.6-0.6-1.1-1.2-0.7-1.3-1.11.11.1-1.5-0.6-1.5-0.4-1.5-0.1-0.70.7-1.4
Stereotopy head waving duration, day 71.72.03.8-1.4-0.10.1-0.1-1.5-1.7-1.3-1.8-1.71.71.7-1.9-1.1-1.9-1.0-2.0-0.8-1.01.0-1.9
Locomotion velocity, session 81.51.83.71.3-1.01.0-0.81.31.50.91.51.5-1.5-1.51.61.91.61.81.61.00.6-0.61.3
Locomotion distance, session 82.02.93.92.0-1.71.7-1.41.81.91.41.91.8-1.8-1.81.91.51.91.41.91.81.4-1.41.2
Degree of sensitization distance0.90.91.70.9-0.60.5-0.30.81.10.51.11.2-1.2-1.21.21.11.31.21.30.40.2-0.21.1
Degree of sensitization stereotypy1.71.83.1-1.40.3-0.30.3-1.4-1.6-1.2-1.6-1.61.61.6-1.7-1.2-1.7-1.1-1.8-0.9-1.01.0-1.6
Conditioned locomotion0.20.31.0-0.7-0.10.0-0.20.2-0.4-0.5-0.1-0.40.40.4-0.2-0.4-0.4-0.4-0.3-0.91.0-1.0-0.9
Cocaine response after cond. corrected1.82.24.21.6-2.02.1-2.01.51.41.61.31.4-1.4-1.41.21.21.21.21.11.71.4-1.40.8
Cocaine response after cond. not corrected0.80.92.01.1-1.41.4-1.30.90.91.00.81.0-1.0-1.00.70.70.70.70.71.10.9-0.90.4
Cocaine response before conditioning1.11.33.1-1.11.7-1.71.8-1.2-1.0-1.3-1.0-0.80.80.8-0.9-1.1-0.8-1.1-0.8-1.3-1.11.1-0.6
Saline control response0.10.10.40.3-0.00.00.00.40.50.50.50.1-0.1-0.10.50.40.60.40.60.50.1-0.10.7
Bone: connectivity density0.50.81.20.9-0.40.4-0.61.11.00.81.11.0-1.0-1.01.10.61.10.71.10.60.9-0.90.9
Bone: cortical apparent density0.20.30.9-0.1-0.40.4-0.7-0.5-0.60.2-0.7-0.60.60.6-0.90.1-0.90.2-0.90.5-0.10.1-0.3
Bone: cortical area6.19.312.0-3.33.4-3.43.3-3.1-3.1-3.5-3.0-2.92.92.9-2.9-3.4-2.9-3.4-2.8-3.1-2.22.2-2.7
Bone: cortical porosity0.50.51.30.6-1.11.1-0.80.70.70.30.70.6-0.6-0.60.70.90.70.80.70.60.6-0.60.1
Bone: cortical porosity0.10.20.90.2-0.91.0-0.60.20.2-0.10.2-0.10.10.10.10.30.10.10.10.50.2-0.2-0.5
Bone: cortical thickness3.86.39.2-2.62.3-2.32.3-2.5-2.6-2.9-2.6-2.52.52.5-2.6-3.0-2.6-3.0-2.6-2.2-1.61.6-2.7
Bone: cortical thickness0.30.41.2-0.2-1.00.9-1.10.2-0.4-0.2-0.2-0.10.10.1-0.30.2-0.50.2-0.4-0.31.1-1.1-1.0
Bone: cortical tissue density0.20.30.9-0.0-0.50.6-0.9-0.4-0.50.4-0.7-0.60.60.6-0.80.2-0.90.3-0.90.6-0.10.1-0.3
Condit. Reinf. active minus inactive responses1.71.94.31.4-2.12.1-2.11.21.21.51.11.1-1.1-1.11.01.41.01.61.01.51.1-1.10.9
Condit. Reinf. active-inactive response ratio3.23.45.12.1-2.22.2-2.11.81.92.21.81.8-1.8-1.81.71.71.71.71.72.11.4-1.41.5
Condit. Reinf. active responses0.70.92.50.9-1.61.5-1.60.80.71.00.70.7-0.7-0.70.61.10.61.20.61.00.7-0.70.6
Condit. Reinf. inactive responses1.11.42.1-1.31.3-1.41.2-1.3-1.3-1.4-1.2-1.11.11.1-1.2-0.9-1.2-0.7-1.1-1.5-1.11.1-0.9
Incentive salience index mean0.20.20.80.4-0.80.8-0.90.30.30.50.20.4-0.4-0.40.20.60.20.70.20.40.4-0.40.3
Condit. Reinf. lever presses0.50.71.6-1.10.8-0.80.6-0.9-1.1-0.9-1.0-0.70.70.7-1.0-0.6-1.0-0.4-1.0-1.3-0.40.4-0.7
Condit. Reinf. active minus inactive responses0.60.71.5-1.01.0-1.01.0-0.9-0.6-0.9-0.6-0.90.90.9-0.5-0.6-0.5-0.6-0.5-0.9-1.21.2-0.3
Condit. Reinf. active-inactive response ratio0.10.20.70.0-0.80.8-0.80.40.20.30.2-0.20.20.20.10.40.10.50.10.20.5-0.5-0.0
Condit. Reinf. active responses0.10.10.2-0.10.3-0.30.30.00.2-0.30.20.0-0.0-0.00.30.30.40.30.4-0.3-0.40.40.4
Condit. Reinf. inactive responses0.10.20.60.40.1-0.1-0.00.10.40.10.40.6-0.6-0.60.50.70.60.70.50.1-0.20.20.6
Condit. Reinf. lever presses0.30.40.8-0.80.4-0.40.4-0.7-0.7-0.8-0.7-0.90.90.9-0.7-0.6-0.7-0.6-0.7-0.6-0.40.4-0.7
Condit. Reinf. lever reinforcers received0.00.10.3-0.40.2-0.20.2-0.1-0.1-0.5-0.0-0.20.20.20.10.10.10.10.1-0.5-0.20.2-0.1
Conditioned reinforcement - actives0.30.61.0-0.90.6-0.60.6-0.6-0.9-0.8-0.8-0.80.80.8-0.8-0.8-0.9-0.8-0.9-0.8-0.00.0-1.0
Conditioned reinforcement - inactives0.60.91.4-1.01.2-1.21.1-0.9-1.0-1.0-0.9-0.80.80.8-0.9-1.0-0.9-1.0-0.9-1.0-0.70.7-0.7
Conditioned locomotion0.91.22.1-1.20.7-0.70.8-1.1-1.3-1.3-1.2-1.11.11.1-1.2-1.2-1.3-1.2-1.2-1.2-0.50.5-1.4
Patch foraging indifference point 0 sec0.00.10.20.3-0.30.3-0.4-0.20.00.1-0.10.2-0.2-0.2-0.10.5-0.00.5-0.10.4-0.10.1-0.0
Patch foraging indifference point AUC0.20.20.90.5-0.00.0-0.20.40.70.80.50.3-0.3-0.30.60.40.60.40.60.7-0.00.00.9
Delay disc. indifference point, 0s delay1.21.35.3-0.8-1.31.3-1.40.2-0.8-1.0-0.5-0.70.70.7-0.8-0.7-1.1-0.7-1.0-0.71.8-1.8-2.3
Delay disc. indifference point, 16s delay0.10.10.40.3-0.30.3-0.50.40.30.40.30.3-0.3-0.30.20.30.20.30.20.40.6-0.60.1
Delay disc. indifference point, 2s delay0.50.62.1-0.0-1.41.4-1.40.6-0.1-0.20.1-0.10.10.1-0.0-0.0-0.2-0.1-0.2-0.01.4-1.4-1.1
Delay disc. indifference point, 24s delay0.30.31.2-0.4-0.30.3-0.50.1-0.4-0.4-0.3-0.40.40.4-0.5-0.4-0.6-0.4-0.6-0.31.0-1.0-1.1
Delay disc. indifference point, 4s delay0.20.20.90.3-0.50.5-0.70.60.30.30.50.3-0.3-0.30.40.30.30.30.30.30.9-0.9-0.1
Delay disc. indifference point, 8s delay0.81.01.5-1.11.2-1.21.1-0.9-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.0-0.50.5-0.9
Indifference point function ln k0.20.40.80.7-0.40.4-0.30.40.60.40.50.9-0.9-0.90.60.90.70.90.60.5-0.00.00.6
Indifference point function log k0.20.40.80.7-0.40.4-0.30.40.60.40.50.9-0.9-0.90.60.90.70.90.60.5-0.00.00.6
Patch foraging total patch changes 0 sec0.00.00.10.2-0.10.2-0.2-0.3-0.00.1-0.20.1-0.1-0.1-0.20.3-0.10.3-0.20.4-0.30.3-0.0
Patch foraging total patch changes 12 sec0.30.40.6-0.70.3-0.30.1-0.7-0.7-0.5-0.7-0.80.80.8-0.7-0.4-0.7-0.3-0.7-0.6-0.30.3-0.6
Patch foraging total patch changes 18 sec0.00.10.20.1-0.20.3-0.4-0.20.00.3-0.1-0.00.00.0-0.10.4-0.10.5-0.10.3-0.10.10.2
Patch foraging total patch changes 24 sec0.10.20.90.2-0.90.9-1.0-0.1-0.2-0.0-0.3-0.10.10.1-0.40.0-0.40.0-0.40.50.4-0.4-0.7
Patch foraging total patch changes 6 sec0.10.10.60.00.4-0.40.3-0.6-0.10.1-0.4-0.20.20.2-0.30.1-0.20.1-0.20.3-0.80.80.3
Patch foraging time to switch 0 sec0.81.74.1-1.50.3-0.30.4-0.9-1.5-1.4-1.3-1.51.51.5-1.5-1.5-1.6-1.6-1.6-1.20.3-0.3-2.0
Patch foraging water rate 0 sec0.51.24.2-0.71.8-1.81.8-1.2-0.5-0.7-0.6-0.50.50.5-0.4-0.3-0.2-0.3-0.2-0.8-2.02.00.5
Patch foraging water rate 12 sec0.10.20.80.5-0.00.10.0-0.10.40.60.10.1-0.1-0.10.20.30.30.40.20.9-0.80.80.8
Patch foraging water rate 18 sec0.20.21.70.10.1-0.10.3-0.6-0.10.1-0.4-0.30.30.3-0.4-0.0-0.20.0-0.30.5-1.31.30.3
Patch foraging water rate 24 sec0.91.25.8-0.61.3-1.31.4-1.4-0.6-0.3-0.9-0.90.90.9-0.7-0.3-0.5-0.3-0.6-0.2-2.42.40.5
Patch foraging water rate 6 sec1.11.55.2-0.91.4-1.41.4-1.6-1.0-0.9-1.3-1.01.01.0-1.2-0.7-1.0-0.7-1.0-0.7-2.32.3-0.3
Seeking ratio, delayed vs. immediate footshock2.02.56.01.9-0.20.2-0.41.41.81.91.71.7-1.7-1.71.81.71.91.71.81.90.2-0.22.4
Distance traveled before self-admin1.52.04.31.3-2.12.1-1.91.41.31.11.31.3-1.3-1.31.31.31.21.31.21.11.5-1.50.6
Distance traveled after self-admin0.30.31.60.2-0.90.9-1.00.60.20.20.30.2-0.2-0.20.20.20.00.20.10.11.3-1.3-0.4
Extensor digitorum longus weight2.39.112.8-3.21.9-1.91.9-3.6-3.3-2.8-3.5-3.43.43.4-3.4-2.7-3.3-2.5-3.4-2.5-3.23.2-2.6
Bone: elastic displacement1.31.52.3-1.51.4-1.51.4-1.1-1.1-1.1-1.0-1.41.41.4-0.9-1.5-0.9-1.4-0.9-1.3-0.80.8-0.7
Bone: elastic work4.15.36.6-2.62.2-2.22.3-2.5-2.3-2.2-2.3-2.62.62.6-2.2-2.5-2.1-2.3-2.1-2.2-2.22.2-1.7
Bone: endosteal estimation1.02.24.3-1.71.9-1.91.9-1.5-1.4-2.0-1.2-1.21.21.2-1.0-1.2-1.0-1.2-0.9-2.1-1.61.6-0.9
Bone: endosteal perimeter1.32.76.5-1.92.5-2.52.4-1.5-1.4-1.8-1.3-1.41.41.4-1.1-1.5-1.1-1.5-1.0-2.2-1.51.5-0.7
Epididymis fat weight1.65.68.3-2.81.5-1.51.4-2.5-2.9-2.7-2.7-2.62.62.6-2.7-2.2-2.8-2.1-2.8-2.7-1.21.2-2.7
Delta time in closed arm before/after self-admin1.01.01.91.0-1.31.3-1.41.00.90.90.90.9-0.9-0.90.80.90.80.90.80.91.2-1.20.5
Delta time in open arm before/after self-admin1.51.52.0-1.40.8-0.80.9-1.2-1.4-1.3-1.3-1.31.31.3-1.3-1.3-1.3-1.3-1.3-1.3-0.70.7-1.4
Diff in mean of infusions in LGA sessions1.31.62.81.2-1.51.5-1.51.51.21.21.31.1-1.1-1.11.11.11.01.11.01.21.7-1.70.7
Delay discount exponential model param0.20.31.10.50.2-0.20.30.00.50.50.30.5-0.5-0.50.50.50.60.50.60.4-0.70.71.1
Extinction: sum of active levers before priming0.80.91.2-1.11.1-1.11.0-0.8-1.1-1.0-1.0-1.01.01.0-1.0-1.0-1.1-1.0-1.0-1.0-0.40.4-0.9
Active lever presses in extinction session 60.30.30.9-0.1-1.01.0-0.90.3-0.2-0.0-0.1-0.10.10.1-0.2-0.1-0.3-0.1-0.30.00.9-0.9-0.8
Bone: final force5.18.113.1-3.12.9-2.93.0-2.8-2.9-3.6-2.7-2.82.82.8-2.6-3.1-2.6-3.1-2.6-3.1-2.12.1-2.8
Bone: final moment4.26.811.0-2.82.6-2.62.8-2.7-2.6-3.3-2.5-2.52.52.5-2.4-2.9-2.3-2.9-2.3-2.6-2.22.2-2.5
Food consumed during 24 hour testing period0.20.21.00.40.4-0.40.5-0.30.2-0.00.10.6-0.6-0.60.20.40.40.40.30.1-1.01.00.6
Glucose0.30.41.5-0.11.0-1.11.2-0.30.1-0.80.10.4-0.4-0.40.30.50.40.40.4-0.7-1.11.10.4
Heart weight1.42.13.8-1.61.8-1.82.0-1.4-1.4-1.6-1.3-1.41.41.4-1.2-1.6-1.2-1.6-1.2-1.5-1.21.2-1.1
Delay discount hyperbolic model param0.20.31.10.50.2-0.20.4-0.00.40.50.30.4-0.4-0.40.40.40.60.40.50.4-0.80.81.1
Intermittent access intake day 1-15 change2.65.36.92.4-2.62.6-2.62.42.42.42.42.1-2.1-2.12.32.32.32.32.32.31.8-1.81.9
Intermittent access intake escalation1.73.54.71.9-2.22.2-2.12.02.01.92.01.7-1.7-1.71.91.91.91.91.91.91.4-1.41.6
Intermittent access intake escalation 22.63.03.71.9-1.71.7-1.71.71.91.81.81.7-1.7-1.71.81.81.91.81.81.80.9-0.91.8
Intermitt. access day 1 inactive lever presses0.10.51.00.9-0.10.1-0.20.70.80.80.70.9-0.9-0.90.70.80.80.80.70.80.5-0.51.0
Intermitt. access day 15 inactive lever presses0.30.71.00.9-0.70.7-0.60.81.00.90.90.8-0.8-0.80.90.91.00.90.90.90.3-0.31.0
Intermitt. access escalation Index0.81.12.11.0-1.41.4-1.31.11.11.01.10.9-0.9-0.91.11.01.11.01.11.00.6-0.60.8
Intermittent access day 1 total infusions0.61.01.9-1.10.9-0.90.8-0.8-1.2-1.1-1.0-0.90.90.9-1.1-1.1-1.3-1.1-1.2-1.10.2-0.2-1.4
Intermittent access day 15 total infusions0.00.00.20.10.0-0.0-0.10.20.00.10.10.1-0.1-0.10.10.10.00.00.00.00.4-0.4-0.0
Intermittent access terminal intake (last 3 days)0.10.10.10.3-0.00.0-0.10.30.30.30.30.3-0.3-0.30.30.30.30.30.30.30.3-0.30.4
Intermittent access total infusions0.10.20.6-0.40.8-0.80.7-0.3-0.4-0.3-0.3-0.30.30.3-0.3-0.4-0.4-0.4-0.4-0.4-0.10.1-0.2
Intermittent access day 1 locomotion0.50.71.1-0.90.8-0.80.7-0.7-1.0-0.9-0.9-0.80.80.8-0.9-0.9-1.0-0.9-1.0-0.9-0.10.1-1.0
Intermittent access day 15 total locomotion0.20.31.0-0.50.1-0.10.0-0.3-0.7-0.6-0.5-0.40.40.4-0.6-0.5-0.7-0.6-0.7-0.60.5-0.5-1.0
Intermittent access total locomotion0.00.00.1-0.10.1-0.1-0.00.0-0.1-0.1-0.10.0-0.0-0.0-0.1-0.1-0.2-0.1-0.2-0.10.4-0.4-0.3
Intermittent access standard deviation0.30.71.00.8-1.01.0-1.00.80.90.80.90.7-0.7-0.70.80.80.80.80.80.80.5-0.50.7
Left kidney weight4.420.624.6-4.73.9-3.94.2-4.8-4.8-4.5-4.9-4.94.94.9-4.8-4.9-4.8-5.0-4.8-3.9-3.83.8-4.2
Right kidney weight3.315.119.0-4.12.9-2.93.1-4.0-4.3-4.0-4.3-4.34.34.3-4.3-4.3-4.3-4.4-4.3-3.4-2.62.6-4.2
Cocaine induced anxiety0.50.71.00.9-1.01.0-0.80.70.90.80.90.8-0.8-0.80.90.81.00.90.90.80.2-0.20.8
Post-drug Anxiety0.40.41.30.4-1.11.1-1.10.70.40.40.50.3-0.3-0.30.40.40.30.40.30.40.9-0.9-0.1
Baseline Anxiety1.61.84.5-1.60.5-0.50.4-0.9-1.6-1.5-1.4-1.51.51.5-1.5-1.4-1.7-1.4-1.7-1.40.5-0.5-2.1
Tail length1.14.37.4-2.02.6-2.62.7-2.2-1.9-1.9-1.9-1.91.91.9-1.8-2.2-1.7-2.2-1.7-1.9-2.32.3-1.1
Length with tail3.917.021.3-4.54.4-4.44.6-4.4-4.2-4.3-4.1-4.14.14.1-3.9-4.1-3.8-4.0-3.8-4.3-4.04.0-3.1
Length without tail3.210.213.5-3.73.2-3.23.3-3.3-3.4-3.4-3.2-3.33.33.3-3.1-3.0-3.1-3.0-3.0-3.6-2.72.7-2.8
Times rat made contact with spout1.21.32.51.4-0.50.4-0.50.91.21.01.11.6-1.6-1.61.21.41.31.41.31.1-0.10.11.5
Lifetime Intake0.20.31.1-0.41.0-1.10.9-0.4-0.4-0.4-0.4-0.30.30.3-0.4-0.4-0.4-0.4-0.4-0.4-0.30.3-0.1
Liver weight, left0.50.91.3-1.20.7-0.70.8-0.9-1.0-1.0-0.9-1.11.11.1-0.9-0.8-0.9-0.8-0.9-1.0-0.80.8-0.8
Liver weight, right2.64.56.6-2.21.3-1.31.3-2.5-2.5-1.8-2.6-2.32.32.3-2.6-2.1-2.5-1.9-2.6-1.8-1.91.9-1.9
Locomotor activity0.50.72.8-0.31.7-1.71.6-0.7-0.1-0.6-0.20.1-0.1-0.10.0-0.10.2-0.10.2-0.7-1.41.40.6
Locomotor testing distance0.50.91.6-1.01.0-1.00.9-1.3-1.1-1.1-1.1-0.90.90.9-1.0-0.6-0.9-0.5-0.9-1.0-1.11.1-0.7
Locomotor testing rearing1.12.23.5-1.51.6-1.61.7-1.8-1.5-1.6-1.6-1.31.31.3-1.4-1.1-1.3-1.0-1.3-1.5-1.91.9-0.9
Locomotion in novel chamber0.81.03.70.9-1.91.9-1.70.90.80.60.80.7-0.7-0.70.80.80.70.80.71.10.8-0.80.1
Locomotion in novel chamber post-restriction0.10.20.90.1-0.60.6-0.60.60.30.10.40.1-0.1-0.10.30.10.20.10.30.10.9-0.9-0.2
Fecal boli incidents, locomotor time 10.40.50.80.9-0.90.9-0.70.50.80.80.70.8-0.8-0.80.70.80.80.80.70.80.1-0.10.8
Change in fecal boli incidents, locomotor task0.30.30.60.6-0.40.4-0.30.50.70.50.70.5-0.5-0.50.70.50.80.50.80.60.0-0.00.7
Time >=10cm from walls, locomotor time 11.51.65.0-1.4-0.10.1-0.0-0.9-1.5-1.4-1.3-1.31.31.3-1.4-1.3-1.6-1.3-1.5-1.30.3-0.3-2.2
Bouts of movement, locomotor time 10.10.20.4-0.3-0.30.3-0.3-0.1-0.4-0.3-0.4-0.30.30.3-0.5-0.3-0.6-0.3-0.6-0.20.4-0.4-0.6
Total resting periods, locomotor time 10.20.20.7-0.3-0.60.6-0.5-0.1-0.5-0.4-0.4-0.30.30.3-0.5-0.3-0.6-0.4-0.6-0.20.5-0.5-0.8
Rest time, locomotor task time 11.62.02.7-1.51.2-1.21.4-1.6-1.5-1.6-1.5-1.31.31.3-1.4-1.3-1.3-1.3-1.3-1.5-1.61.6-1.0
Distance moved, locomotor task time 10.10.10.50.40.1-0.1-0.00.30.40.50.30.1-0.1-0.10.30.10.30.10.30.70.2-0.20.3
Vertical activity count, locomotor time 10.51.21.81.2-0.50.6-0.81.31.31.31.31.1-1.1-1.11.31.11.31.11.21.21.0-1.01.1
Time >=10cm from walls, locomotor time 20.50.81.4-1.10.8-0.80.7-0.8-1.0-1.0-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-1.2-0.50.5-1.1
Bouts of movement, locomotor time 20.10.10.40.2-0.40.4-0.50.30.10.30.10.2-0.2-0.20.00.2-0.00.2-0.00.30.6-0.6-0.2
Total resting periods, locomotor time 20.00.10.2-0.10.0-0.0-0.1-0.0-0.2-0.0-0.2-0.20.20.2-0.3-0.1-0.4-0.2-0.3-0.10.4-0.4-0.4
Rest time, locomotor task time 21.41.73.3-1.41.8-1.81.7-1.3-1.2-1.2-1.2-1.21.21.2-1.2-1.3-1.1-1.3-1.1-1.4-1.21.2-0.6
Distance moved, locomotor task time 20.50.61.00.8-1.01.0-1.00.90.80.80.80.6-0.6-0.60.80.60.80.60.70.90.7-0.70.4
Vertical activity count, locomotor time 21.62.23.51.5-1.91.9-1.81.61.51.41.61.4-1.4-1.41.51.51.51.51.51.31.3-1.30.8
Light reinforcement 11.84.45.8-2.21.5-1.51.6-2.3-2.3-2.0-2.3-2.42.42.4-2.3-2.1-2.3-2.1-2.3-1.8-1.81.8-2.0
Light reinforcement 22.53.84.7-2.01.6-1.61.8-2.2-2.1-2.0-2.1-2.02.02.0-2.1-1.9-2.0-1.8-2.0-1.7-2.22.2-1.6
Bone: marrow area0.91.94.1-1.71.7-1.81.8-1.4-1.3-1.9-1.1-1.11.11.1-1.0-1.1-0.9-1.1-0.9-2.0-1.41.4-0.9
Bone: maximum diameter4.07.59.3-2.73.1-3.03.0-3.0-2.8-2.7-2.9-2.62.62.6-2.8-2.9-2.7-2.8-2.7-2.3-2.72.7-2.0
Bone: maximum force3.76.59.2-2.82.9-2.92.8-2.6-2.6-3.0-2.5-2.52.52.5-2.4-2.5-2.3-2.5-2.3-2.7-2.22.2-2.1
Bone: maximum moment3.05.37.3-2.42.5-2.52.6-2.5-2.2-2.7-2.3-2.22.22.2-2.1-2.3-2.0-2.3-2.0-2.2-2.22.2-1.8
Mean time between licks in bursts0.71.83.61.6-0.30.3-0.10.91.51.31.31.8-1.8-1.81.51.31.71.31.61.2-0.40.41.9
Mean num. licks in bursts2.94.55.92.3-2.22.2-2.32.12.22.42.12.0-2.0-2.02.02.32.12.42.02.31.5-1.52.0
Cd content in liver0.10.10.2-0.20.2-0.30.40.20.30.10.3-0.10.10.10.40.10.40.10.4-0.2-0.30.30.4
Co content in liver0.40.51.6-0.80.8-0.81.0-0.3-0.5-1.3-0.3-0.50.50.5-0.3-0.7-0.3-0.9-0.3-1.00.1-0.1-1.0
Cu content in liver1.21.42.01.3-1.21.1-1.21.31.20.71.31.4-1.4-1.41.31.01.21.01.20.91.2-1.20.6
Fe content in liver4.55.57.92.5-2.82.8-2.52.62.31.62.42.5-2.5-2.52.32.32.22.02.22.22.5-2.50.9
K content in liver0.20.21.0-0.40.3-0.3-0.00.4-0.1-0.20.1-0.30.30.30.1-0.5-0.1-0.6-0.0-0.41.0-1.0-0.4
Mg content in liver1.41.53.3-1.41.1-1.11.0-1.0-1.2-1.2-1.1-1.41.41.4-1.1-1.8-1.2-1.8-1.1-1.2-0.30.3-1.3
Mn content in liver0.30.30.80.30.4-0.40.20.60.70.50.70.3-0.3-0.30.80.50.80.40.80.20.4-0.40.9
Na content in liver0.50.62.50.4-0.60.6-0.60.90.5-0.20.70.7-0.7-0.70.60.70.50.50.60.01.6-1.6-0.5
Rb content in liver0.20.31.0-0.30.6-0.60.7-0.3-0.4-1.0-0.30.0-0.0-0.0-0.3-0.6-0.3-0.8-0.3-0.70.1-0.1-0.8
Se content in liver0.20.21.10.3-0.70.7-0.90.20.30.70.1-0.40.40.40.00.40.10.5-0.01.10.2-0.20.4
Sr content in liver2.42.02.8-1.51.4-1.41.4-1.6-1.4-1.1-1.5-1.71.71.7-1.4-1.3-1.3-1.3-1.4-1.1-1.71.7-0.8
Zn content in liver0.30.31.20.1-0.20.3-0.4-0.6-0.20.4-0.5-0.50.50.5-0.50.4-0.30.5-0.40.7-1.11.10.3
Bone: minimum diameter1.62.86.4-1.72.5-2.52.5-1.6-1.5-2.1-1.3-1.21.21.2-1.2-1.7-1.1-1.7-1.1-2.1-1.51.5-1.0
Time in familiar zone, hab. session 10.90.81.71.2-1.21.2-0.80.91.00.90.90.9-0.9-0.90.80.80.80.70.81.30.7-0.70.5
Time in novel zone, hab. session 10.60.61.1-0.90.8-0.80.4-0.9-0.7-0.3-0.8-1.01.01.0-0.7-0.6-0.7-0.4-0.7-0.6-1.11.1-0.1
Total zone transitions, hab. session 10.20.30.90.6-0.30.2-0.20.50.40.30.50.9-0.9-0.90.50.50.50.50.50.20.5-0.50.4
Total locomotion distance, hab. session 10.71.02.01.0-0.40.4-0.41.01.00.81.11.4-1.4-1.41.10.91.11.01.10.40.9-0.91.1
Locomotion velocity, hab. session 10.40.51.20.50.2-0.30.30.70.60.20.81.1-1.1-1.10.80.30.80.40.9-0.20.9-0.90.7
Time in familiar zone, hab. session 24.14.36.32.2-2.52.5-2.52.22.02.12.01.9-1.9-1.91.82.31.82.31.82.31.8-1.81.5
Time in novel zone, hab. session 27.17.28.9-2.72.8-2.82.8-3.0-2.7-2.3-2.8-2.72.72.7-2.6-2.9-2.5-2.9-2.5-2.3-2.82.8-1.7
Total zone transitions, hab. session 20.00.00.20.1-0.10.1-0.2-0.3-0.10.1-0.2-0.00.00.0-0.20.1-0.10.2-0.20.3-0.50.50.1
Total locomotion distance, hab. session 20.10.10.30.3-0.00.0-0.0-0.20.10.2-0.00.1-0.1-0.10.00.10.10.30.10.4-0.50.50.5
Locomotion velocity, hab. session 20.00.00.20.3-0.10.0-0.1-0.10.10.20.00.2-0.2-0.20.00.10.10.30.10.4-0.30.30.4
Novel to familiar place preference ratio0.10.10.40.20.2-0.20.00.40.30.20.40.5-0.5-0.50.40.10.30.10.4-0.00.6-0.60.3
Novelty place preference0.10.10.30.10.5-0.60.40.20.10.10.20.3-0.3-0.30.2-0.10.2-0.10.2-0.10.3-0.30.3
Time in novel zone, NPP test0.10.10.50.00.7-0.70.50.00.00.10.10.2-0.2-0.20.1-0.10.1-0.10.1-0.20.0-0.00.3
Total zone transitions, NPP test0.10.20.40.3-0.60.6-0.60.40.20.30.30.5-0.5-0.50.30.30.20.50.20.10.7-0.70.1
Total locomotion distance, NPP test0.60.81.40.9-1.11.1-1.10.90.70.80.81.0-1.0-1.00.70.70.70.80.70.71.2-1.20.5
Locomotion velocity, NPP test0.91.32.61.1-1.41.4-1.41.21.01.01.11.2-1.2-1.21.00.90.91.00.90.81.6-1.60.5
Intraocular pressure0.30.50.7-0.60.6-0.60.5-0.7-0.6-0.3-0.7-0.80.80.8-0.7-0.9-0.6-0.8-0.7-0.2-0.90.9-0.3
Delta distance traveled before/after self-admin0.60.71.1-0.90.7-0.70.5-0.5-0.9-0.8-0.8-0.90.90.9-0.9-0.9-1.0-0.9-1.0-0.80.3-0.3-1.1
Delta ambulatory time before/after self-admin0.10.10.40.2-0.20.2-0.30.40.20.30.20.1-0.1-0.10.10.10.10.10.10.20.6-0.6-0.0
Parametrial fat weight0.30.61.70.8-1.31.3-1.20.80.70.80.70.5-0.5-0.50.60.60.60.60.51.10.9-0.90.2
Pavlov. Cond. lever latency0.91.22.91.2-1.71.7-1.41.01.21.11.00.9-0.9-0.91.00.81.00.81.01.40.4-0.40.7
Pavlov. Cond. magazine entry latency0.70.92.01.1-0.40.4-0.50.71.01.30.80.9-0.9-0.90.91.30.91.40.91.10.3-0.31.4
Pavlov. Cond. change in total contacts0.10.10.3-0.00.5-0.50.40.20.00.30.10.3-0.3-0.30.10.10.10.10.1-0.30.4-0.40.4
Pavlov. Cond. index score0.10.10.40.10.5-0.50.20.20.20.30.20.3-0.3-0.30.20.60.20.70.2-0.10.4-0.40.6
Pavlov. Cond. latency score0.10.10.6-0.10.8-0.80.50.0-0.10.10.00.1-0.1-0.10.00.4-0.00.50.0-0.30.3-0.30.4
Pavlov. Cond. lever contacts0.60.72.0-0.91.4-1.41.2-0.7-0.9-1.0-0.7-0.60.60.6-0.7-0.6-0.7-0.6-0.7-1.2-0.20.2-0.5
Pavlov. Cond. magazine entry number1.11.42.4-1.30.7-0.60.8-1.1-1.3-1.4-1.2-1.21.21.2-1.2-1.5-1.2-1.6-1.2-1.2-0.80.8-1.5
Pavlov. Cond. intertrial magazine entries0.40.40.8-0.4-0.80.9-0.7-0.6-0.6-0.4-0.7-0.70.70.7-0.8-0.7-0.8-0.6-0.80.0-0.50.5-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.00.7-0.70.40.10.10.20.10.2-0.2-0.20.10.40.10.40.1-0.20.3-0.30.5
Pavlov. Cond. response bias0.20.20.50.50.2-0.20.10.40.40.50.40.5-0.5-0.50.40.60.40.60.40.30.4-0.40.7
Pavlov. Cond. lever latency0.50.61.1-0.80.2-0.20.4-0.7-0.9-0.7-0.8-1.01.01.0-0.9-1.1-0.9-1.0-0.9-0.6-0.40.4-1.0
Pavlov. Cond. magazine entry latency1.21.41.9-1.11.1-1.11.1-1.3-1.4-1.4-1.3-1.01.01.0-1.3-1.3-1.3-1.4-1.3-1.2-0.90.9-1.3
Pavlov. Cond. change in total contacts0.00.00.1-0.00.0-0.0-0.1-0.1-0.10.1-0.1-0.00.00.0-0.10.2-0.10.2-0.1-0.0-0.00.00.1
Pavlov. Cond. index score0.00.00.10.00.3-0.20.1-0.2-0.10.0-0.10.1-0.1-0.1-0.10.2-0.10.2-0.1-0.1-0.20.20.2
Pavlov. Cond. latency score0.00.00.10.00.3-0.30.2-0.2-0.1-0.0-0.10.1-0.1-0.1-0.10.2-0.00.2-0.0-0.1-0.20.20.2
Pavlov. Cond. lever contacts0.81.21.71.1-0.50.5-0.71.11.21.01.21.3-1.3-1.31.21.31.21.31.20.80.8-0.81.2
Pavlov. Cond. magazine entry number1.62.02.91.4-1.51.4-1.51.71.61.51.61.2-1.2-1.21.51.31.51.31.51.41.4-1.41.2
Pavlov. Cond. intertrial magazine entries0.71.01.70.9-0.70.7-0.81.11.10.91.21.0-1.0-1.01.21.31.21.31.20.60.7-0.71.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.10.3-0.30.2-0.3-0.2-0.1-0.20.0-0.0-0.0-0.20.1-0.20.1-0.2-0.2-0.20.20.1
Pavlov. Cond. response bias0.00.10.20.20.0-0.0-0.00.10.20.10.20.4-0.4-0.40.20.30.20.30.30.00.2-0.20.3
Time in closed arm before self-admin0.20.31.1-0.31.0-1.01.0-0.5-0.3-0.2-0.4-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.80.80.2
Time in closed arm after self-admin0.40.40.60.7-0.80.8-0.80.60.60.70.60.7-0.7-0.70.60.70.60.70.50.70.5-0.50.5
Time in open arm before self-admin0.20.20.3-0.50.4-0.40.4-0.5-0.4-0.5-0.4-0.40.40.4-0.4-0.4-0.3-0.4-0.4-0.5-0.50.5-0.4
Time in open arm after self-admin1.61.82.3-1.51.2-1.21.3-1.3-1.4-1.5-1.3-1.41.41.4-1.3-1.4-1.3-1.4-1.3-1.5-1.01.0-1.3
Bone: periosteal estimation3.67.511.4-3.03.4-3.43.3-2.8-2.7-3.3-2.6-2.52.52.5-2.4-2.7-2.3-2.7-2.3-3.3-2.32.3-2.2
Bone: periosteal perimeter4.27.310.9-3.13.3-3.33.2-2.6-2.7-3.1-2.5-2.62.62.6-2.3-2.9-2.4-2.9-2.3-3.2-1.81.8-2.2
Bone: post-yield work0.60.92.41.1-0.90.9-1.00.60.91.10.70.9-0.9-0.90.71.50.81.50.81.10.1-0.11.1
Progressive ratio test 1 active lever presses0.91.12.7-1.11.6-1.61.4-1.0-1.1-1.0-1.0-0.90.90.9-1.1-1.0-1.1-1.1-1.1-1.1-0.40.4-0.8
Progressive ratio test 1 breakpoint0.91.12.6-1.01.6-1.61.4-0.9-1.1-1.0-1.0-0.90.90.9-1.0-1.0-1.1-1.0-1.1-1.0-0.30.3-0.8
Progressive ratio test 1 inactive lever presses0.20.30.7-0.40.9-0.90.7-0.5-0.5-0.5-0.5-0.30.30.3-0.5-0.5-0.5-0.5-0.5-0.5-0.20.2-0.3
Progressive ratio test 2 active lever presses0.10.10.4-0.10.7-0.70.40.0-0.2-0.1-0.1-0.00.00.0-0.2-0.2-0.3-0.2-0.2-0.20.5-0.5-0.1
Progressive ratio test 2 breakpoint0.10.10.4-0.20.7-0.70.4-0.0-0.2-0.1-0.2-0.10.10.1-0.2-0.2-0.3-0.2-0.3-0.20.4-0.4-0.2
Progressive ratio test 2 inactive lever presses0.30.51.0-0.71.0-1.00.9-0.6-0.8-0.7-0.7-0.60.60.6-0.8-0.8-0.8-0.8-0.8-0.8-0.00.0-0.7
Incentive Sensitization - Responses0.10.10.50.3-0.10.1-0.20.40.20.30.30.4-0.4-0.40.20.30.20.20.20.20.7-0.70.1
Incentive Sensitization - Breakpoint0.10.10.40.3-0.10.1-0.20.40.20.20.20.3-0.3-0.30.20.20.10.20.10.20.6-0.60.1
Sum of active levers in priming session hrs 5-60.10.10.60.1-0.40.4-0.50.3-0.00.20.10.1-0.1-0.1-0.10.1-0.20.1-0.10.20.7-0.7-0.3
Progressive ratio0.20.30.5-0.60.7-0.70.6-0.4-0.5-0.6-0.4-0.60.60.6-0.4-0.6-0.4-0.6-0.4-0.6-0.30.3-0.4
Food seeking constrained by brief footshock1.82.35.7-1.82.3-2.42.0-1.3-1.5-1.2-1.3-1.41.41.4-1.2-1.4-1.3-1.4-1.3-1.9-0.80.8-0.7
Seeking ratio, punishment vs. effort0.10.10.8-0.10.9-0.90.7-0.1-0.00.2-0.00.1-0.1-0.10.00.10.00.10.0-0.3-0.20.20.6
Retroperitoneal fat weight0.41.53.2-1.50.3-0.30.4-0.9-1.4-1.4-1.3-1.51.51.5-1.4-1.4-1.5-1.4-1.5-1.3-0.00.0-1.8
Reaction time number correct1.01.97.9-0.71.8-1.71.9-1.8-0.9-0.7-1.2-0.90.90.9-1.0-0.5-0.7-0.5-0.8-0.5-2.82.80.2
Reaction time mean minus median0.71.72.11.5-1.31.3-1.31.31.41.41.31.4-1.4-1.41.31.41.31.41.31.30.9-0.91.2
Reaction time mean minus median AUC0.00.10.2-0.1-0.40.4-0.3-0.2-0.3-0.1-0.3-0.10.10.1-0.4-0.2-0.4-0.2-0.4-0.00.1-0.1-0.5
Reaction time num false alarms1.01.43.9-1.3-0.00.0-0.0-0.7-1.3-1.2-1.1-1.41.41.4-1.3-1.3-1.4-1.4-1.4-1.10.7-0.7-2.0
Reaction time num false alarms AUC1.42.15.4-1.70.1-0.00.0-1.1-1.7-1.5-1.5-1.81.81.8-1.7-1.6-1.9-1.6-1.8-1.20.3-0.3-2.3
Reaction time trials correct on left1.01.97.9-0.71.8-1.71.9-1.8-0.9-0.7-1.2-0.90.90.9-1.0-0.5-0.7-0.5-0.8-0.5-2.82.80.2
Reaction time trials on left0.91.77.5-0.61.6-1.61.7-1.7-0.8-0.6-1.2-0.80.80.8-0.9-0.4-0.7-0.4-0.8-0.3-2.72.70.3
Reaction time mean1.11.83.41.3-1.41.4-1.51.61.31.21.41.3-1.3-1.31.31.11.21.01.21.21.8-1.80.7
Reaction time mean AUC1.11.73.21.3-1.41.4-1.51.51.31.21.41.3-1.3-1.31.21.01.11.01.21.11.8-1.80.7
Median of all reaction times1.01.43.71.1-1.21.2-1.31.51.10.91.31.1-1.1-1.11.20.81.00.71.10.91.9-1.90.5
Reaction time omissions0.60.91.71.1-1.31.3-1.30.80.81.20.70.8-0.8-0.80.60.90.61.00.61.30.7-0.70.7
Reaction time false alarm rate1.01.44.6-1.2-0.70.7-0.8-0.2-1.1-1.0-0.8-1.31.31.3-1.1-1.2-1.4-1.3-1.3-0.81.5-1.5-2.1
Reaction time premature initiation rate0.10.10.40.0-0.60.6-0.6-0.1-0.20.0-0.2-0.10.10.1-0.30.0-0.40.0-0.40.20.4-0.4-0.5
Reaction time premature initiations0.20.41.1-0.30.2-0.20.3-1.0-0.6-0.3-0.8-0.50.50.5-0.8-0.2-0.7-0.2-0.80.1-1.01.0-0.4
Std. dev. reaction times0.71.32.41.2-1.51.5-1.51.11.01.11.01.1-1.1-1.10.91.10.81.10.81.21.2-1.20.6
Reaction time trials completed0.91.77.5-0.61.6-1.61.7-1.7-0.8-0.6-1.2-0.80.80.8-0.9-0.4-0.7-0.4-0.8-0.3-2.72.70.3
Reaction time trials AUC0.81.67.4-0.61.6-1.61.7-1.7-0.7-0.5-1.1-0.80.80.8-0.9-0.4-0.6-0.3-0.7-0.3-2.72.70.4
Run reversals in cocaine runway, females1.81.85.30.9-1.91.8-1.91.61.01.01.21.0-1.0-1.01.01.00.81.00.90.72.3-2.3-0.1
Run reversals in cocaine runway, males0.30.30.7-0.70.8-0.80.7-0.4-0.5-0.2-0.5-0.60.60.6-0.5-0.6-0.5-0.6-0.5-0.8-0.20.2-0.2
Latency to leave start box in cocaine runway1.11.23.5-1.3-0.20.20.1-1.0-1.2-1.5-1.1-1.21.21.2-1.2-1.2-1.2-1.2-1.2-1.2-0.40.4-1.9
Latency to leave start box in cocaine runway, F2.32.64.9-1.90.6-0.60.8-1.6-1.9-1.9-1.8-1.71.71.7-1.8-1.7-1.8-1.7-1.8-1.9-0.70.7-2.2
Latency to leave start box in cocaine runway, M0.20.11.00.1-1.01.0-0.70.00.1-0.30.10.0-0.0-0.00.00.00.10.00.00.2-0.00.0-0.6
Std. dev. time between licks in bursts0.20.30.80.40.4-0.40.40.30.50.10.60.9-0.9-0.90.70.40.80.40.8-0.2-0.20.20.8
Total sessions with >9 infusions0.10.10.2-0.30.5-0.50.4-0.2-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.4-0.4-0.3-0.40.1-0.1-0.3
Short access day 1 total inactive lever presses0.00.00.1-0.2-0.10.10.1-0.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.2-0.2-0.2-0.40.4-0.2
Short access day 10 total inactive lever presses0.41.02.41.2-0.50.5-0.40.61.21.11.01.1-1.1-1.11.11.11.31.11.21.1-0.40.41.5
Short access day 1 total infusions0.00.00.1-0.20.1-0.10.00.0-0.2-0.1-0.1-0.20.20.2-0.2-0.2-0.3-0.2-0.2-0.20.3-0.3-0.3
Short access day 10 total infusions0.10.21.2-0.01.1-1.10.9-0.1-0.00.0-0.10.0-0.0-0.0-0.0-0.1-0.0-0.1-0.0-0.1-0.20.20.5
Short access total infusions0.10.10.60.00.7-0.80.60.00.00.10.00.1-0.1-0.10.0-0.00.0-0.00.0-0.0-0.00.00.4
Short access day 1 locomotion0.40.51.2-0.81.1-1.10.9-0.6-0.8-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.30.3-0.5
Short access day 10 total locomotion1.22.32.91.7-1.51.5-1.41.41.71.61.61.6-1.6-1.61.61.61.61.61.61.60.7-0.71.6
Short access total locomotion0.50.60.80.9-0.50.5-0.60.70.80.80.80.9-0.9-0.90.80.80.80.80.80.80.4-0.40.9
One hour access (0.3 mA shock)0.00.00.2-0.10.3-0.30.4-0.3-0.1-0.2-0.2-0.00.00.0-0.1-0.2-0.1-0.2-0.1-0.2-0.40.40.0
Compulsive drug intake0.20.31.20.3-1.11.1-1.00.40.40.30.40.1-0.1-0.10.40.40.40.40.40.40.2-0.2-0.0
One hour access (shock baseline)0.00.10.2-0.10.5-0.50.5-0.2-0.2-0.2-0.20.1-0.1-0.1-0.1-0.2-0.1-0.2-0.1-0.2-0.10.10.0
Social response proportion1.11.23.01.3-0.50.5-0.50.81.31.41.11.1-1.1-1.11.21.31.31.31.31.4-0.10.11.7
Social responses0.20.31.70.10.7-0.60.7-0.50.10.1-0.2-0.10.10.1-0.10.00.10.10.00.3-1.31.30.7
Social time1.11.52.11.3-0.90.9-0.91.41.41.31.41.3-1.3-1.31.41.41.41.41.41.10.8-0.81.4
Soleus weight2.78.114.1-2.62.6-2.62.8-3.5-2.8-2.3-3.1-3.03.03.0-3.0-2.8-2.7-2.6-2.8-1.8-3.73.7-1.7
Bone: stiffness0.91.43.9-1.51.3-1.41.2-0.9-1.3-1.9-1.0-0.80.80.8-0.9-1.1-1.0-1.2-0.9-2.0-0.10.1-1.5
Tibialis anterior weight1.34.36.0-2.21.3-1.31.3-2.5-2.3-1.9-2.4-2.32.32.3-2.4-1.9-2.3-1.7-2.3-1.8-2.12.1-1.8
Time to tail flick, vehicle, before self-admin0.90.92.60.9-1.61.6-1.50.90.70.80.70.7-0.7-0.70.60.80.60.80.60.91.1-1.10.1
Time to tail flick, vehicle, after self-admin0.50.61.40.8-1.21.2-1.20.80.70.80.70.6-0.6-0.60.60.60.60.70.60.90.8-0.80.4
Time to tail flick, test, before self-admin0.10.10.2-0.30.4-0.40.4-0.4-0.3-0.2-0.3-0.30.30.3-0.3-0.3-0.2-0.3-0.2-0.2-0.40.4-0.1
Time to tail flick, test, after self-admin1.01.03.5-0.71.9-1.91.8-1.0-0.6-0.6-0.7-0.60.60.6-0.5-0.6-0.4-0.6-0.4-0.7-1.51.50.3
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.40.7-0.70.6-0.4-0.3-0.3-0.3-0.40.40.4-0.3-0.4-0.2-0.4-0.2-0.3-0.50.50.1
Delta time to tail flick, test, before/after SA0.30.31.5-0.11.2-1.21.1-0.30.00.0-0.1-0.10.10.10.1-0.10.2-0.00.1-0.0-0.90.90.8
Tibia length1.43.97.6-2.12.4-2.42.4-1.6-1.9-2.8-1.6-1.61.61.6-1.6-2.5-1.6-2.6-1.5-2.3-0.90.9-2.0
Ambulatory time before self-admin1.21.75.21.1-2.32.3-2.11.31.00.91.11.1-1.1-1.11.01.10.91.10.90.81.5-1.50.0
Ambulatory time after self-admin1.61.94.21.1-2.12.0-2.01.61.01.01.21.1-1.1-1.11.01.10.91.10.90.92.0-2.00.1
Bone: tissue strength2.62.76.6-1.32.2-2.22.4-1.8-1.1-1.3-1.3-1.41.41.4-1.1-1.5-0.9-1.5-1.0-1.0-2.62.6-0.3
Total heroin consumption0.40.51.2-0.60.5-0.50.7-0.9-0.8-0.6-0.8-0.60.60.6-0.8-0.6-0.7-0.6-0.7-0.6-1.11.1-0.6
Bone: trabecular number0.30.61.21.0-0.50.6-0.70.80.81.10.70.9-0.9-0.90.70.30.70.40.71.00.5-0.50.9
Bone: trabecular spacing1.72.34.4-1.72.1-2.12.1-1.5-1.4-1.8-1.4-1.41.41.4-1.2-1.3-1.2-1.4-1.2-1.7-1.11.1-1.1
Bone: trabecular thickness1.51.93.81.4-1.31.2-1.61.21.21.51.21.6-1.6-1.61.21.81.11.91.11.01.0-1.01.4
Bone: trabecular tissue density0.30.41.00.6-0.20.2-0.30.80.60.20.71.0-1.0-1.00.70.30.60.30.70.11.0-1.00.3
Water consumed over 24 hours1.01.43.51.30.2-0.20.40.71.41.01.21.5-1.5-1.51.41.11.51.11.51.0-0.60.61.9
Number of responses in last shaping day0.30.32.00.0-0.70.7-0.90.6-0.00.10.20.1-0.1-0.10.00.0-0.20.0-0.10.01.4-1.4-0.7