Hub : Genes

LOC103692581

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	alternative TSS	XR_001838302.3	0.1	0.07	5.0e-06	0.03	0.03	0.03	0.02	1.6e-04	1.0e-04	1.4e-04	2.5e-03
2	Brain	gene expression	LOC103692581	0.05	0.03	1.6e-04	0.05	0.04	0.04	0.04	1.4e-05	7.9e-05	4.8e-05	5.2e-05
3	Adipose	gene expression	LOC103692581	0.3	0.11	9.4e-15	0.08	0.09	0.1	0.07	7.8e-09	6.5e-10	6.0e-11	2.0e-08
4	PL	gene expression	LOC103692581	0.07	0.05	1.4e-05	0.03	0.04	0.03	0.04	4.3e-04	9.2e-05	6.5e-04	7.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	4.0	7.0	8.5	-2.5	2.5	2.6	2.9
Area under the delay curve	0.2	0.2	0.5	-0.7	0.4	0.5	0.3
BMI with tail	1.5	5.1	9.0	3.0	-2.4	-2.1	-1.2
BMI without tail	1.0	3.0	6.3	2.5	-1.8	-1.6	-0.3
Body weight	1.3	5.8	7.8	2.7	-2.8	-2.2	-1.8
Weight adjusted by age	0.2	0.2	0.3	-0.2	0.5	0.6	0.6
Bone surface	0.4	0.7	1.0	-0.7	0.8	0.7	1.0
Bone volume	1.5	2.7	3.2	-1.6	1.7	1.5	1.8
Breakpoint value in progressive ratio session	2.9	3.5	5.1	-1.8	2.3	1.6	1.7
Number of licking bursts	2.4	3.9	4.3	2.0	-2.1	-2.1	-1.7
Context. condit. distance diff. score	1.1	1.3	2.8	-0.5	0.8	1.2	1.7
Locomotion velocity, session 1	0.7	0.7	1.0	0.9	-1.0	-0.7	-0.8
Locomotion distance, session 1	0.5	0.6	1.0	-0.9	0.8	1.0	0.4
Locomotion velocity, session 2	0.8	1.0	1.8	1.1	-0.8	-1.3	-0.6
Locomotion distance, session 2	0.0	0.0	0.1	-0.1	0.0	-0.1	-0.3
Locomotion velocity, session 3	0.3	0.4	0.6	-0.5	0.5	0.6	0.8
Locomotion distance, session 3	0.9	1.0	1.3	-1.0	0.7	1.1	1.1
Stereotopy head waving bouts, day 3	1.6	1.9	2.3	-1.4	1.5	1.2	1.4
Stereotopy head waving duration, day 3	0.0	0.0	0.0	-0.1	0.0	-0.1	0.1
Locomotion velocity, session 7	0.0	0.0	0.1	-0.0	0.2	-0.3	0.2
Locomotion distance, session 7	0.4	0.6	0.7	0.9	-0.8	-0.9	-0.3
Stereotopy head waving bouts, day 7	0.1	0.1	0.1	0.0	-0.3	0.0	-0.4
Stereotopy head waving duration, day 7	0.1	0.1	0.2	-0.3	-0.0	0.4	-0.1
Locomotion velocity, session 8	0.4	0.5	1.3	-0.3	0.5	0.5	1.2
Locomotion distance, session 8	2.0	2.9	4.2	-1.3	1.7	1.6	2.1
Degree of sensitization distance	2.9	3.0	4.1	2.0	-1.7	-1.8	-1.4
Degree of sensitization stereotypy	0.6	0.6	1.2	0.6	-0.9	-0.4	-1.1
Conditioned locomotion	3.1	3.6	4.7	-1.7	1.7	2.2	2.0
Cocaine response after cond. corrected	0.1	0.1	0.2	0.4	-0.2	-0.2	-0.1
Cocaine response after cond. not corrected	0.0	0.0	0.0	-0.2	-0.0	0.2	-0.2
Cocaine response before conditioning	0.7	0.9	2.2	-1.5	0.4	1.0	0.3
Saline control response	0.9	1.2	2.6	-1.6	0.9	1.1	0.5
Bone: connectivity density	1.3	2.0	3.5	-1.1	1.2	1.3	1.9
Bone: cortical apparent density	0.1	0.1	0.2	0.0	-0.3	-0.4	-0.4
Bone: cortical area	0.2	0.3	0.7	0.5	-0.3	-0.4	-0.9
Bone: cortical porosity	0.2	0.2	0.3	-0.5	0.4	0.5	0.4
Bone: cortical porosity	0.4	0.5	0.7	-0.6	0.6	0.6	0.8
Bone: cortical thickness	0.9	1.4	3.1	0.8	-0.9	-1.0	-1.8
Bone: cortical thickness	0.3	0.4	0.7	-0.8	0.6	0.7	-0.0
Bone: cortical tissue density	0.1	0.2	0.3	0.1	-0.4	-0.5	-0.4
Condit. Reinf. active minus inactive responses	4.9	5.4	6.2	2.5	-2.3	-2.5	-2.0
Condit. Reinf. active-inactive response ratio	2.5	2.7	3.3	1.7	-1.7	-1.8	-1.3
Condit. Reinf. active responses	1.1	1.4	1.8	1.3	-1.3	-1.2	-0.9
Condit. Reinf. inactive responses	0.7	0.9	1.3	-0.7	0.8	1.1	1.2
Incentive salience index mean	1.4	1.7	1.9	1.3	-1.3	-1.4	-1.2
Condit. Reinf. lever presses	0.4	0.5	1.1	-1.0	0.5	0.8	0.2
Condit. Reinf. active minus inactive responses	0.1	0.1	0.3	0.5	-0.2	0.1	0.1
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.5	-0.1	0.3	0.1
Condit. Reinf. active responses	0.1	0.2	0.3	0.4	-0.4	-0.1	-0.5
Condit. Reinf. inactive responses	0.1	0.1	0.3	-0.3	-0.2	0.1	-0.6
Condit. Reinf. lever presses	0.1	0.2	0.6	-0.0	-0.2	-0.3	-0.8
Condit. Reinf. lever reinforcers received	0.3	0.5	0.6	0.7	-0.7	-0.5	-0.8
Conditioned reinforcement - actives	1.9	3.2	5.4	-1.7	2.3	1.5	1.5
Conditioned reinforcement - inactives	0.7	1.0	1.7	-1.3	1.2	0.6	0.7
Conditioned locomotion	0.4	0.5	1.4	-1.2	0.7	-0.0	0.0
Patch foraging indifference point 0 sec	0.2	0.4	0.7	-0.7	0.5	0.5	0.8
Patch foraging indifference point AUC	0.1	0.2	0.5	0.3	0.0	0.4	0.7
Delay disc. indifference point, 0s delay	0.4	0.5	0.6	0.7	-0.6	-0.7	-0.8
Delay disc. indifference point, 16s delay	0.7	0.8	1.0	-1.0	0.9	0.9	0.6
Delay disc. indifference point, 2s delay	0.2	0.2	0.4	0.2	-0.4	-0.6	-0.5
Delay disc. indifference point, 24s delay	4.6	5.2	6.8	-2.2	2.6	2.3	2.0
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	-0.6	0.1	0.3	0.1
Delay disc. indifference point, 8s delay	0.7	0.8	1.0	-1.0	1.0	0.9	0.7
Indifference point function ln k	0.7	1.2	2.3	-1.5	1.1	1.0	0.3
Indifference point function log k	0.7	1.2	2.3	-1.5	1.1	1.0	0.3
Patch foraging total patch changes 0 sec	0.2	0.4	0.6	-0.7	0.5	0.5	0.8
Patch foraging total patch changes 12 sec	0.1	0.1	0.3	0.4	-0.5	-0.2	-0.0
Patch foraging total patch changes 18 sec	0.3	0.4	1.3	0.1	0.1	0.5	1.1
Patch foraging total patch changes 24 sec	0.1	0.1	0.1	0.3	-0.3	-0.3	-0.0
Patch foraging total patch changes 6 sec	0.1	0.1	0.1	0.4	-0.1	-0.3	0.3
Patch foraging time to switch 0 sec	0.1	0.2	0.5	0.5	-0.3	-0.7	0.0
Patch foraging water rate 0 sec	1.5	3.1	4.7	-2.2	1.7	1.9	1.2
Patch foraging water rate 12 sec	0.2	0.4	1.1	0.1	-0.6	-0.5	-1.1
Patch foraging water rate 18 sec	1.2	1.8	3.7	-1.9	1.1	1.5	0.1
Patch foraging water rate 24 sec	0.0	0.0	0.1	-0.3	0.1	0.3	-0.0
Patch foraging water rate 6 sec	0.2	0.3	0.8	-0.9	0.5	0.5	-0.2
Seeking ratio, delayed vs. immediate footshock	1.2	1.4	2.9	1.7	-0.4	-1.4	-0.8
Distance traveled before self-admin	0.0	0.0	0.0	0.1	0.1	0.2	-0.1
Distance traveled after self-admin	0.2	0.3	0.9	0.2	0.9	0.3	0.4
Extensor digitorum longus weight	1.3	5.2	6.0	-2.4	2.4	2.2	2.0
Bone: elastic displacement	0.9	1.0	1.3	-1.0	1.0	1.2	0.9
Bone: elastic work	1.2	1.6	2.2	-1.3	1.5	1.2	0.8
Bone: endosteal estimation	0.5	1.0	2.2	-0.5	1.1	0.8	1.5
Bone: endosteal perimeter	0.1	0.2	0.4	-0.2	0.4	0.5	0.7
Epididymis fat weight	10.8	36.9	46.9	6.5	-6.9	-5.2	-5.5
Delta time in closed arm before/after self-admin	0.6	0.5	0.8	-0.6	0.6	0.9	0.8
Delta time in open arm before/after self-admin	0.7	0.7	1.2	0.9	-1.1	-0.5	-0.7
Diff in mean of infusions in LGA sessions	0.1	0.2	0.4	-0.3	0.6	0.2	0.3
Delay discount exponential model param	0.6	0.6	1.1	1.0	-0.7	-0.8	-0.6
Extinction: sum of active levers before priming	3.3	3.6	4.1	-1.8	2.0	2.0	1.7
Active lever presses in extinction session 6	3.0	3.0	5.3	-1.2	2.3	1.5	1.7
Bone: final force	0.3	0.4	0.6	0.6	-0.5	-0.7	-0.8
Bone: final moment	0.1	0.2	0.3	0.5	-0.3	-0.5	-0.6
Food consumed during 24 hour testing period	0.6	0.8	1.4	0.8	-1.2	-0.8	-0.9
Glucose	0.8	1.2	2.2	1.1	-1.5	-0.9	-0.7
Heart weight	1.3	2.0	2.8	1.7	-1.5	-1.4	-1.0
Delay discount hyperbolic model param	0.2	0.2	0.5	0.7	-0.3	-0.5	-0.3
Intermittent access intake day 1-15 change	0.7	1.4	2.3	-1.2	1.5	0.8	1.1
Intermittent access intake escalation	0.5	1.0	1.7	-1.0	1.3	0.6	0.9
Intermittent access intake escalation 2	0.8	1.0	2.2	-0.6	1.5	0.4	1.1
Intermitt. access day 1 inactive lever presses	0.1	0.5	0.9	0.5	-1.0	-0.7	-0.6
Intermitt. access day 15 inactive lever presses	0.1	0.2	0.4	0.5	-0.6	-0.4	-0.3
Intermitt. access escalation Index	1.0	1.4	2.6	1.6	-1.0	-1.3	-0.5
Intermittent access day 1 total infusions	0.3	0.5	1.3	-1.1	0.4	0.6	0.1
Intermittent access day 15 total infusions	0.7	1.1	2.1	-1.5	1.3	0.7	0.5
Intermittent access terminal intake (last 3 days)	0.7	1.0	1.9	-1.4	1.3	0.5	0.0
Intermittent access total infusions	1.0	1.2	3.3	-1.8	0.9	0.8	0.2
Intermittent access day 1 locomotion	0.5	0.7	1.4	-0.5	-0.7	-0.7	-1.2
Intermittent access day 15 total locomotion	0.5	1.0	2.1	0.2	-1.0	-0.9	-1.4
Intermittent access total locomotion	0.5	0.5	1.1	-0.9	-0.2	-0.4	-1.0
Intermittent access standard deviation	0.4	0.9	1.3	-1.1	0.8	0.8	1.0
Left kidney weight	0.1	0.4	0.6	0.8	-0.8	-0.5	-0.3
Right kidney weight	0.5	2.2	2.9	1.7	-1.7	-1.3	-1.1
Cocaine induced anxiety	0.8	1.2	1.6	-1.1	1.1	0.9	1.3
Post-drug Anxiety	0.2	0.2	0.3	0.6	-0.6	0.0	-0.1
Baseline Anxiety	3.8	4.4	5.4	2.3	-2.2	-1.6	-2.2
Tail length	0.1	0.4	0.8	-0.9	0.4	0.6	0.4
Length with tail	0.1	0.6	1.2	0.1	-0.9	-0.6	-1.1
Length without tail	0.1	0.2	0.7	-0.3	-0.5	0.0	-0.8
Times rat made contact with spout	2.3	2.7	3.2	-1.8	1.4	1.8	1.6
Lifetime Intake	0.8	0.9	2.9	-1.7	0.6	0.7	0.0
Liver weight, left	2.0	3.3	6.2	1.2	-1.7	-1.6	-2.5
Liver weight, right	2.7	4.7	6.1	2.5	-2.2	-2.3	-1.6
Locomotor activity	1.8	2.7	3.3	1.7	-1.8	-1.8	-1.3
Locomotor testing distance	1.1	1.9	2.9	1.3	-1.7	-1.5	-0.9
Locomotor testing rearing	0.5	0.9	1.6	0.8	-1.0	-1.2	-0.7
Locomotion in novel chamber	1.4	1.7	2.7	0.6	-1.5	-1.3	-1.7
Locomotion in novel chamber post-restriction	1.0	1.6	2.4	1.0	-1.5	-0.9	-1.5
Fecal boli incidents, locomotor time 1	1.2	1.7	3.3	-1.8	1.0	1.2	1.1
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.4	-0.5	-0.1	-0.3
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	-0.2	-0.3	0.1	0.0
Bouts of movement, locomotor time 1	0.2	0.3	0.9	-0.9	0.3	-0.1	-0.2
Total resting periods, locomotor time 1	0.2	0.2	0.7	-0.8	0.1	-0.2	-0.1
Rest time, locomotor task time 1	0.1	0.2	0.5	-0.3	-0.2	-0.7	-0.3
Distance moved, locomotor task time 1	0.2	0.3	0.9	0.9	-0.6	-0.1	-0.2
Vertical activity count, locomotor time 1	0.0	0.0	0.1	0.2	-0.1	0.1	-0.2
Time >=10cm from walls, locomotor time 2	0.2	0.3	0.5	-0.7	-0.5	0.6	0.4
Bouts of movement, locomotor time 2	0.0	0.0	0.1	-0.3	0.0	-0.3	-0.2
Total resting periods, locomotor time 2	0.0	0.0	0.1	-0.2	-0.1	-0.3	-0.2
Rest time, locomotor task time 2	0.1	0.1	0.4	0.0	-0.4	-0.6	-0.1
Distance moved, locomotor task time 2	0.0	0.0	0.1	0.3	0.0	0.0	-0.3
Vertical activity count, locomotor time 2	0.0	0.1	0.1	-0.4	0.2	0.3	-0.1
Light reinforcement 1	0.0	0.0	0.0	-0.2	0.1	-0.2	-0.1
Light reinforcement 2	0.7	1.0	1.6	-1.0	0.7	1.3	0.9
Bone: marrow area	0.4	0.9	2.0	-0.5	1.0	0.7	1.4
Bone: maximum diameter	0.2	0.4	0.8	-0.4	0.7	0.9	0.4
Bone: maximum force	0.0	0.1	0.2	0.2	0.2	-0.5	-0.2
Bone: maximum moment	0.0	0.1	0.2	0.1	0.5	-0.3	0.1
Mean time between licks in bursts	0.4	1.0	1.2	1.1	-1.1	-1.0	-0.9
Mean num. licks in bursts	5.1	7.9	9.0	-2.9	2.8	3.0	2.6
Cd content in liver	0.5	0.6	1.1	1.1	-1.1	-0.2	-0.2
Co content in liver	0.7	0.8	1.1	-1.1	1.0	0.9	0.6
Cu content in liver	0.5	0.6	1.2	0.8	-0.6	-1.1	-0.1
Fe content in liver	1.5	1.8	2.5	-1.4	1.3	1.1	1.6
K content in liver	1.1	1.1	1.5	1.2	-1.2	-1.0	-0.6
Mg content in liver	0.1	0.1	0.2	0.4	-0.4	-0.4	-0.0
Mn content in liver	0.5	0.5	1.2	0.5	-0.5	-1.1	-0.5
Na content in liver	0.7	0.8	1.3	-1.1	0.8	0.8	0.6
Rb content in liver	0.1	0.2	0.2	0.4	-0.5	-0.2	0.5
Se content in liver	0.4	0.5	0.8	0.3	-0.5	-0.9	-0.8
Sr content in liver	2.3	2.0	3.2	-1.8	1.5	1.1	1.2
Zn content in liver	2.1	2.3	2.9	1.7	-1.6	-1.4	-1.3
Bone: minimum diameter	1.4	2.5	3.3	1.7	-1.4	-1.8	-1.4
Time in familiar zone, hab. session 1	0.8	0.8	1.1	0.8	-0.7	-1.0	-1.0
Time in novel zone, hab. session 1	0.3	0.3	0.6	0.7	-0.6	-0.6	0.1
Total zone transitions, hab. session 1	0.5	0.6	1.2	-1.0	0.5	1.1	0.4
Total locomotion distance, hab. session 1	0.5	0.7	1.5	-1.2	0.7	0.9	0.2
Locomotion velocity, hab. session 1	0.9	1.3	2.5	-1.6	1.0	1.3	0.4
Time in familiar zone, hab. session 2	0.1	0.1	0.3	-0.1	0.5	-0.5	0.3
Time in novel zone, hab. session 2	0.6	0.7	1.2	1.0	-1.1	-0.5	-0.4
Total zone transitions, hab. session 2	1.0	1.3	1.9	-1.3	0.9	1.4	1.0
Total locomotion distance, hab. session 2	1.0	1.4	1.5	-1.2	1.0	1.2	1.2
Locomotion velocity, hab. session 2	1.3	1.8	2.1	-1.4	1.1	1.5	1.3
Novel to familiar place preference ratio	0.7	0.7	1.6	0.9	-0.6	-1.3	-0.5
Novelty place preference	1.4	1.5	2.8	1.3	-0.9	-1.7	-0.9
Time in novel zone, NPP test	1.3	1.4	2.7	1.2	-0.8	-1.6	-0.8
Total zone transitions, NPP test	1.4	2.0	3.2	-1.3	1.0	1.8	1.4
Total locomotion distance, NPP test	2.0	2.7	3.2	-1.7	1.4	1.7	1.8
Locomotion velocity, NPP test	2.3	3.2	4.1	-2.0	1.4	2.0	1.6
Intraocular pressure	1.3	1.8	2.7	1.7	-1.3	-1.2	-1.1
Delta distance traveled before/after self-admin	0.2	0.3	0.7	0.8	-0.2	-0.5	-0.2
Delta ambulatory time before/after self-admin	0.1	0.1	0.3	0.1	0.6	-0.0	0.5
Parametrial fat weight	19.7	46.2	53.9	7.3	-7.3	-6.3	-6.2
Pavlov. Cond. lever latency	0.4	0.5	0.8	0.8	-0.4	-0.9	-0.5
Pavlov. Cond. magazine entry latency	0.9	1.1	1.9	-0.9	0.7	1.4	1.0
Pavlov. Cond. change in total contacts	0.4	0.4	0.6	-0.7	0.8	0.4	0.5
Pavlov. Cond. index score	0.7	0.9	1.3	-1.1	0.7	1.1	0.9
Pavlov. Cond. latency score	0.7	0.9	1.2	-1.0	0.6	1.1	0.9
Pavlov. Cond. lever contacts	0.5	0.6	1.1	-1.0	0.5	1.1	0.5
Pavlov. Cond. magazine entry number	1.5	1.9	2.5	1.2	-1.1	-1.5	-1.6
Pavlov. Cond. intertrial magazine entries	1.6	1.9	2.4	-1.6	1.3	1.4	1.2
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	1.9	-1.3	1.0	1.4	1.1
Pavlov. Cond. response bias	2.1	2.6	3.5	-1.6	1.4	1.9	1.6
Pavlov. Cond. lever latency	0.0	0.0	0.1	0.3	-0.0	-0.1	-0.1
Pavlov. Cond. magazine entry latency	0.4	0.5	1.1	1.1	-0.7	-0.7	0.0
Pavlov. Cond. change in total contacts	0.3	0.5	0.8	0.8	-0.9	-0.6	-0.6
Pavlov. Cond. index score	0.0	0.1	0.1	0.3	-0.3	-0.2	0.0
Pavlov. Cond. latency score	0.0	0.1	0.1	0.3	-0.3	-0.2	0.2
Pavlov. Cond. lever contacts	0.0	0.0	0.1	-0.0	-0.3	-0.1	-0.2
Pavlov. Cond. magazine entry number	0.5	0.7	1.3	-1.1	0.9	0.8	0.1
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.4	0.2	-0.2	-0.5	-0.7
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.2	0.4	-0.4	-0.3	0.0
Pavlov. Cond. response bias	0.0	0.0	0.0	-0.1	-0.2	0.1	0.2
Time in closed arm before self-admin	0.1	0.1	0.5	0.3	-0.7	0.1	0.1
Time in closed arm after self-admin	0.9	0.9	1.1	1.1	-1.0	-0.8	-1.0
Time in open arm before self-admin	0.0	0.1	0.1	-0.3	0.2	0.0	-0.2
Time in open arm after self-admin	0.0	0.0	0.1	-0.2	-0.1	-0.0	-0.1
Bone: periosteal estimation	0.1	0.2	0.4	-0.2	0.7	0.4	0.6
Bone: periosteal perimeter	0.1	0.2	0.3	-0.5	0.3	0.5	0.1
Bone: post-yield work	2.2	3.2	3.8	-1.7	1.8	1.6	1.9
Progressive ratio test 1 active lever presses	0.2	0.3	0.5	-0.6	-0.3	-0.4	-0.7
Progressive ratio test 1 breakpoint	0.2	0.2	0.5	-0.7	-0.2	-0.2	-0.6
Progressive ratio test 1 inactive lever presses	0.9	1.3	2.1	-0.0	-1.5	-1.4	-1.1
Progressive ratio test 2 active lever presses	1.1	1.3	2.4	-1.5	1.5	0.7	0.3
Progressive ratio test 2 breakpoint	1.0	1.2	2.2	-1.5	1.5	0.6	0.1
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.7	-0.8	0.3	0.1	0.1
Incentive Sensitization - Responses	1.1	1.5	4.0	-1.0	2.0	0.8	0.6
Incentive Sensitization - Breakpoint	0.9	1.2	3.5	-0.9	1.9	0.6	0.3
Sum of active levers in priming session hrs 5-6	1.1	1.1	1.7	-0.9	1.0	0.9	1.3
Progressive ratio	0.4	0.6	1.2	1.0	-1.1	-0.6	-0.1
Food seeking constrained by brief footshock	4.9	6.0	8.5	-2.9	2.1	2.6	2.0
Seeking ratio, punishment vs. effort	1.9	2.8	3.8	-2.0	1.8	1.7	1.1
Retroperitoneal fat weight	25.7	109.6	128.5	11.2	-11.3	-9.9	-9.3
Reaction time number correct	0.0	0.1	0.3	0.1	-0.6	0.1	0.1
Reaction time mean minus median	0.3	0.7	0.9	0.9	-0.9	-0.8	-0.8
Reaction time mean minus median AUC	0.4	1.1	1.4	1.2	-1.1	-1.0	-0.9
Reaction time num false alarms	0.3	0.5	0.7	0.8	-0.8	-0.5	-0.5
Reaction time num false alarms AUC	0.3	0.5	0.8	0.7	-0.9	-0.5	-0.7
Reaction time trials correct on left	0.0	0.1	0.3	0.1	-0.6	0.1	0.1
Reaction time trials on left	0.1	0.1	0.4	0.1	-0.6	-0.0	-0.0
Reaction time mean	0.2	0.3	0.7	0.5	-0.1	-0.8	-0.6
Reaction time mean AUC	0.2	0.3	0.7	0.5	-0.1	-0.8	-0.6
Median of all reaction times	0.1	0.1	0.4	0.1	0.3	-0.6	-0.3
Reaction time omissions	0.2	0.4	0.7	0.8	-0.5	-0.6	-0.3
Reaction time false alarm rate	0.2	0.3	0.6	0.6	-0.5	-0.4	-0.8
Reaction time premature initiation rate	0.3	0.4	0.9	-1.0	0.2	0.9	0.2
Reaction time premature initiations	0.2	0.4	0.7	-0.8	-0.1	0.8	0.3
Std. dev. reaction times	0.2	0.4	0.6	0.8	-0.6	-0.7	-0.6
Reaction time trials completed	0.1	0.1	0.4	0.1	-0.6	-0.0	-0.0
Reaction time trials AUC	0.1	0.2	0.5	0.2	-0.7	-0.2	-0.2
Run reversals in cocaine runway, females	1.6	1.6	2.2	-0.9	1.3	1.2	1.5
Run reversals in cocaine runway, males	0.2	0.2	0.4	-0.2	0.6	0.3	-0.3
Latency to leave start box in cocaine runway	3.1	3.5	4.7	-1.5	1.7	2.0	2.2
Latency to leave start box in cocaine runway, F	2.3	2.6	3.8	-1.1	1.5	1.9	1.7
Latency to leave start box in cocaine runway, M	1.2	1.1	1.8	-1.0	0.8	0.9	1.4
Std. dev. time between licks in bursts	0.4	0.5	0.8	0.5	-0.6	-0.9	-0.9
Total sessions with >9 infusions	0.5	0.6	1.7	-1.3	-0.4	-0.1	-0.7
Short access day 1 total inactive lever presses	0.3	0.3	1.2	-1.1	-0.2	0.2	0.3
Short access day 10 total inactive lever presses	0.1	0.3	0.9	-0.3	-0.4	0.2	0.9
Short access day 1 total infusions	0.2	0.3	0.6	-0.8	-0.6	-0.1	-0.2
Short access day 10 total infusions	1.0	1.3	3.3	-1.8	0.7	1.1	0.3
Short access total infusions	0.3	0.4	1.3	-1.1	-0.3	0.2	-0.4
Short access day 1 locomotion	0.2	0.3	0.4	-0.6	-0.4	-0.5	-0.7
Short access day 10 total locomotion	0.1	0.2	0.4	-0.7	-0.4	-0.4	-0.3
Short access total locomotion	0.5	0.6	0.7	-0.8	-0.8	-0.7	-0.9
One hour access (0.3 mA shock)	3.2	3.6	5.7	-2.1	2.4	1.2	1.7
Compulsive drug intake	0.3	0.4	0.6	0.8	-0.6	-0.6	0.1
One hour access (shock baseline)	1.9	2.9	4.8	-2.2	2.1	1.3	1.0
Social response proportion	0.2	0.2	0.8	0.3	0.1	-0.9	-0.4
Social responses	0.6	0.7	1.3	1.0	-0.5	-1.1	-0.5
Social time	0.2	0.3	0.8	-0.7	0.1	-0.2	-0.9
Soleus weight	4.3	12.6	14.7	-3.8	3.4	3.7	3.2
Bone: stiffness	0.6	1.0	1.5	1.2	-0.7	-1.2	-0.8
Tibialis anterior weight	1.5	5.2	6.2	-2.4	2.5	2.3	1.9
Time to tail flick, vehicle, before self-admin	0.6	0.6	1.4	0.0	-0.7	-0.6	-1.2
Time to tail flick, vehicle, after self-admin	1.9	2.5	4.0	1.5	-2.0	-1.5	-1.2
Time to tail flick, test, before self-admin	1.1	1.2	1.8	-1.3	1.3	0.9	0.6
Time to tail flick, test, after self-admin	1.1	1.2	2.6	-1.6	0.8	0.9	0.8
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.4	0.5	-0.6	-0.1	0.2
Delta time to tail flick, test, before/after SA	0.5	0.5	1.2	-1.1	0.2	0.5	0.8
Tibia length	2.0	5.6	6.5	2.5	-2.4	-2.3	-2.2
Ambulatory time before self-admin	0.0	0.0	0.1	0.1	0.3	0.2	-0.2
Ambulatory time after self-admin	0.2	0.3	0.7	0.5	0.9	0.0	0.3
Bone: tissue strength	0.3	0.3	0.7	0.2	0.3	-0.8	-0.7
Total heroin consumption	3.6	4.3	5.4	-2.3	2.3	1.6	1.9
Bone: trabecular number	3.4	5.7	6.5	-2.4	2.3	2.3	2.5
Bone: trabecular spacing	2.5	3.3	4.1	1.8	-1.5	-1.9	-2.0
Bone: trabecular thickness	1.9	2.4	3.0	-1.6	1.3	1.7	1.4
Bone: trabecular tissue density	0.1	0.2	0.6	-0.3	-0.2	0.8	0.4
Water consumed over 24 hours	0.1	0.2	0.3	0.5	-0.3	-0.5	0.4
Number of responses in last shaping day	0.3	0.3	0.6	-0.8	-0.3	0.5	0.6