Hub : Genes

LOC102555451

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability LOC102555451 0.29 0.1 1.7e-08 0.11 0.12 0.11 0.13 3.1e-06 4.0e-07 1.8e-06 2.4e-07
2 IL gene expression LOC102555451 0.59 0.13 2.9e-10 0.29 0.28 0.3 0.29 9.8e-08 1.8e-07 4.8e-08 1.3e-07
3 BLA gene expression LOC102555451 0.38 0.1 5.4e-14 0.25 0.26 0.26 0.25 2.4e-13 8.4e-14 2.7e-14 2.6e-13
4 IC mRNA stability LOC102555451 0.21 0.1 3.7e-05 0.07 0.1 0.07 0.08 6.0e-04 8.3e-05 9.0e-04 4.2e-04
5 Brain gene expression LOC102555451 0.26 0.09 0.0e+00 0.23 0.24 0.23 0.23 7.1e-21 7.8e-22 2.0e-21 2.8e-21
6 IC gene expression LOC102555451 0.38 0.14 1.4e-09 0.21 0.18 0.2 0.21 2.6e-09 6.0e-08 7.4e-09 2.6e-09
7 pVTA gene expression LOC102555451 0.14 0.07 2.6e-05 0.05 0.07 0.06 0.06 4.6e-05 1.6e-06 1.6e-05 1.9e-05
8 pVTA intron excision ratio chr19_41000795_41003481 0.06 0.04 2.7e-03 0 0.01 0 0 1.8e-01 4.4e-02 1.2e-01 1.7e-01
9 pVTA mRNA stability LOC102555451 0.1 0.05 4.7e-05 0.02 0.05 0.04 0.05 4.4e-03 5.8e-05 2.8e-04 7.9e-05
10 Brain mRNA stability LOC102555451 0.29 0.09 0.0e+00 0.17 0.28 0.28 0.28 1.2e-15 6.1e-26 3.1e-26 1.0e-26
11 PL mRNA stability LOC102555451 0.19 0.07 1.1e-16 0.12 0.16 0.16 0.16 1.9e-13 1.6e-17 3.5e-17 7.9e-17
12 IL mRNA stability LOC102555451 0.33 0.13 7.0e-05 0.12 0.2 0.22 0.16 8.6e-04 1.3e-05 5.9e-06 9.8e-05
13 Adipose gene expression LOC102555451 0.1 0.05 2.0e-08 0.06 0.07 0.07 0.07 1.8e-07 1.7e-08 1.4e-08 1.6e-08
14 NAcc gene expression LOC102555451 0.15 0.06 0.0e+00 0.1 0.12 0.12 0.12 1.5e-14 4.0e-17 2.8e-17 4.6e-17
15 PL gene expression LOC102555451 0.26 0.08 0.0e+00 0.23 0.21 0.22 0.24 3.9e-25 2.3e-22 3.6e-23 1.4e-25
16 OFC mRNA stability LOC102555451 0.48 0.14 5.7e-06 0.13 0.19 0.11 0.15 6.7e-04 2.5e-05 1.3e-03 2.1e-04
17 NAcc mRNA stability LOC102555451 0.14 0.05 0.0e+00 0.13 0.12 0.13 0.13 1.6e-19 2.0e-18 1.2e-19 1.6e-19
18 NAcc alternative TSS XR_005496875.2 0.04 0.02 6.3e-03 0 0 -0 -0 1.2e-01 2.8e-01 9.8e-01 5.8e-01
19 OFC gene expression LOC102555451 0.43 0.13 7.5e-06 0.14 0.12 0.14 0.04 3.8e-04 7.2e-04 4.3e-04 4.9e-02
20 Adipose mRNA stability LOC102555451 0.05 0.03 2.9e-04 0.01 0.03 0.01 0.02 9.8e-03 4.5e-04 6.8e-03 2.4e-03
21 pVTA alternative TSS XR_005496875.2 0.06 0.04 2.8e-03 0.01 0.01 0.01 0.02 3.0e-02 3.8e-02 4.7e-02 7.2e-03
22 PL isoform ratio XR_005496875.2 0.17 0.13 7.1e-03 0.01 0 0.03 0.01 3.2e-02 9.8e-02 5.8e-04 2.7e-02
23 PL isoform ratio XR_005496878.2 0.03 0.02 6.3e-03 0.01 0.02 0.01 0.01 5.0e-02 3.4e-03 3.6e-02 3.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.83.48.42.4-2.7-2.31.71.7-2.22.51.51.71.41.3-2.5-1.8-1.71.62.1-1.31.1-2.91.40.90.1-0.0
Area under the delay curve0.20.41.6-0.60.50.3-0.7-0.50.4-0.1-0.6-0.2-0.7-0.90.10.50.4-0.5-0.20.81.3-0.80.2-0.80.50.9
BMI with tail1.34.611.7-2.73.42.6-2.8-2.42.6-1.6-1.3-2.3-1.4-1.83.22.62.5-2.8-0.51.50.42.0-0.9-0.6-1.6-1.6
BMI without tail0.10.51.5-0.61.10.3-1.0-0.60.30.6-0.5-1.0-0.6-0.91.20.60.5-0.70.10.81.1-0.50.4-0.7-1.2-0.2
Body weight0.10.42.70.10.8-0.20.40.6-0.20.40.6-0.00.70.61.0-0.4-0.50.3-0.3-0.2-1.60.90.60.3-0.4-0.6
Weight adjusted by age0.10.41.5-0.90.30.9-0.7-0.70.9-1.2-0.7-0.3-0.9-0.5-0.00.80.6-0.6-0.30.20.50.4-0.8-0.2-0.40.3
Bone surface1.22.37.01.7-1.9-2.31.71.5-2.32.60.50.70.40.6-1.2-1.5-1.22.50.3-0.10.7-2.60.6-0.51.31.4
Bone volume1.32.77.42.0-2.2-2.42.01.7-2.42.70.80.90.71.0-1.5-1.7-1.42.60.6-0.50.5-2.60.6-0.10.81.0
Breakpoint value in progressive ratio session0.91.64.80.8-0.6-0.21.01.0-0.2-0.31.61.21.81.7-0.7-0.8-0.70.01.3-1.9-2.21.40.52.1-1.1-2.2
Number of licking bursts0.20.73.10.8-0.4-0.80.40.9-0.81.01.11.01.00.7-0.5-1.0-1.10.01.3-0.7-0.1-0.71.80.6-0.3-0.6
Context. condit. distance diff. score0.50.61.6-1.01.21.0-0.9-0.61.0-1.1-0.4-0.4-0.5-0.60.90.40.4-1.1-0.80.3-0.41.30.1-0.3-0.30.1
Locomotion velocity, session 10.80.93.11.3-0.9-1.41.21.1-1.31.70.80.60.90.9-0.4-1.1-0.91.30.8-0.4-0.3-1.00.60.30.7-0.3
Locomotion distance, session 10.81.02.11.1-0.4-1.00.91.1-1.11.11.41.01.41.1-0.4-0.9-0.90.51.1-0.8-1.1-0.11.30.91.2-1.0
Locomotion velocity, session 20.60.71.71.1-0.7-0.90.60.9-0.91.00.91.00.90.7-0.7-1.1-1.20.31.1-0.50.2-1.01.30.20.1-0.1
Locomotion distance, session 20.60.82.30.70.1-0.50.60.9-0.60.51.30.81.51.10.1-0.8-0.8-0.00.9-0.9-1.50.71.21.1-0.1-1.3
Locomotion velocity, session 30.20.20.5-0.40.40.2-0.4-0.50.2-0.0-0.7-0.7-0.7-0.70.50.50.50.0-0.70.60.5-0.1-0.5-0.6-0.00.5
Locomotion distance, session 30.70.83.60.10.0-0.8-0.10.2-0.81.4-0.5-0.1-0.7-0.70.2-0.5-0.50.6-0.60.91.3-1.81.0-1.31.21.9
Stereotopy head waving bouts, day 32.02.44.6-1.51.51.0-1.4-1.61.0-0.4-2.1-2.0-2.1-2.01.81.51.5-0.4-1.92.21.6-0.2-1.5-2.10.61.5
Stereotopy head waving duration, day 30.91.11.7-1.11.10.9-1.2-1.20.9-0.5-1.3-1.3-1.3-1.31.11.21.1-0.8-0.81.31.20.0-0.8-1.20.20.6
Locomotion velocity, session 70.10.20.5-0.50.70.2-0.5-0.20.20.0-0.3-0.4-0.4-0.50.70.10.0-0.3-0.60.40.10.10.4-0.5-0.30.5
Locomotion distance, session 70.40.51.10.7-0.5-0.70.70.8-0.70.50.90.71.10.8-0.5-0.8-0.80.30.6-0.8-0.8-0.00.90.8-0.3-0.5
Stereotopy head waving bouts, day 71.01.14.4-0.40.5-0.2-0.7-0.4-0.20.7-1.1-0.7-1.3-1.30.60.20.10.1-1.01.51.8-1.50.3-1.91.22.1
Stereotopy head waving duration, day 70.60.83.40.1-0.1-0.6-0.20.0-0.61.1-0.6-0.2-0.8-0.80.1-0.2-0.30.4-0.31.01.7-1.80.6-1.41.01.6
Locomotion velocity, session 80.50.53.20.6-0.0-0.50.90.9-0.50.30.80.51.01.00.2-0.9-0.70.7-0.1-0.6-1.80.80.40.5-0.3-0.6
Locomotion distance, session 80.30.51.80.20.5-0.00.10.5-0.1-0.11.00.61.00.60.3-0.6-0.7-0.50.4-0.7-1.30.91.30.9-0.4-0.9
Degree of sensitization distance1.01.13.80.4-0.40.10.70.50.1-0.71.20.71.41.3-0.6-0.3-0.3-0.10.9-1.5-2.01.6-0.11.7-1.1-1.9
Degree of sensitization stereotypy0.60.62.4-0.30.4-0.2-0.6-0.3-0.20.5-0.8-0.4-0.9-1.00.40.20.0-0.1-0.61.21.4-1.20.4-1.51.01.5
Conditioned locomotion0.20.20.60.4-0.3-0.50.70.6-0.50.30.50.40.50.6-0.3-0.5-0.40.60.1-0.4-0.80.00.20.40.2-0.2
Cocaine response after cond. corrected0.40.62.7-0.00.30.30.30.30.3-0.50.70.30.80.80.3-0.2-0.2-0.30.4-1.0-1.61.50.01.2-1.6-1.5
Cocaine response after cond. not corrected0.71.05.20.30.00.30.40.50.2-0.51.00.51.01.1-0.0-0.4-0.4-0.40.9-1.4-1.51.40.21.6-2.3-1.9
Cocaine response before conditioning0.20.20.80.6-0.6-0.60.30.4-0.60.70.30.40.20.2-0.7-0.5-0.50.20.6-0.20.5-0.90.60.10.10.2
Saline control response3.54.88.02.3-2.2-2.02.12.4-2.11.62.82.72.82.6-2.4-2.3-2.21.22.3-2.6-2.0-0.52.62.50.1-1.5
Bone: connectivity density2.64.214.02.5-2.8-2.71.71.8-2.63.11.21.71.11.0-2.6-2.0-2.01.91.9-0.91.8-3.71.80.30.70.9
Bone: cortical apparent density0.61.04.7-0.91.00.7-1.6-1.10.8-0.1-0.9-0.7-1.0-1.50.70.80.6-1.40.11.12.2-0.90.5-1.00.00.6
Bone: cortical area0.40.72.60.6-0.4-0.91.01.0-0.90.80.90.71.00.9-0.4-0.9-0.81.0-0.0-0.7-1.60.20.90.60.9-0.1
Bone: cortical porosity0.50.52.7-0.60.30.7-0.1-0.40.7-1.4-0.3-0.1-0.10.00.10.50.7-0.1-1.0-0.1-1.41.6-0.80.11.00.1
Bone: cortical porosity0.40.52.2-0.50.30.40.1-0.10.4-1.0-0.3-0.1-0.2-0.00.20.30.40.4-1.40.1-1.41.4-0.6-0.31.50.7
Bone: cortical thickness0.30.51.8-0.91.20.7-0.7-0.50.7-0.8-0.1-0.30.1-0.30.80.50.5-0.8-0.60.1-1.01.40.30.20.5-0.3
Bone: cortical thickness2.12.58.30.6-0.70.4-0.40.20.5-0.81.91.62.11.2-1.9-0.2-0.3-2.12.9-2.2-0.40.61.82.8-1.6-2.8
Bone: cortical tissue density0.61.04.8-0.91.00.7-1.6-1.00.70.0-1.0-0.8-1.1-1.50.70.70.5-1.3-0.01.22.2-1.00.5-1.20.10.8
Condit. Reinf. active minus inactive responses1.61.87.4-1.61.60.5-1.3-0.80.4-0.2-1.5-0.9-1.6-1.81.30.60.2-0.4-2.31.80.8-0.20.8-1.91.72.7
Condit. Reinf. active-inactive response ratio0.60.61.8-1.21.10.6-0.9-0.40.6-0.8-0.6-0.2-0.7-0.80.60.40.0-0.7-1.30.6-0.30.70.9-0.61.01.3
Condit. Reinf. active responses1.11.46.3-1.01.10.1-0.9-0.50.10.2-1.2-0.6-1.3-1.50.90.30.0-0.1-1.71.61.1-0.80.8-1.81.92.5
Condit. Reinf. inactive responses0.81.13.61.2-1.1-1.41.00.9-1.41.70.30.60.30.3-0.8-1.1-0.91.50.30.10.7-1.90.6-0.51.41.0
Incentive salience index mean1.21.58.4-0.60.7-0.5-0.4-0.1-0.50.9-1.2-0.7-1.3-1.40.8-0.0-0.30.7-1.91.61.0-1.30.8-1.92.12.9
Condit. Reinf. lever presses0.91.35.80.4-0.3-1.20.40.4-1.21.6-0.7-0.3-0.9-0.70.1-0.6-0.61.6-1.21.21.1-1.90.3-1.51.92.4
Condit. Reinf. active minus inactive responses0.20.31.80.20.0-0.60.50.3-0.70.7-0.2-0.4-0.1-0.00.5-0.3-0.01.1-0.90.6-0.6-0.1-0.2-0.61.30.7
Condit. Reinf. active-inactive response ratio0.10.10.5-0.20.20.20.1-0.20.2-0.4-0.3-0.4-0.1-0.00.50.20.40.3-0.70.2-0.70.7-0.7-0.20.30.1
Condit. Reinf. active responses0.10.20.70.4-0.2-0.60.60.4-0.60.60.3-0.10.40.40.2-0.3-0.00.8-0.20.0-0.90.1-0.00.20.8-0.1
Condit. Reinf. inactive responses0.20.21.20.2-0.20.00.20.1-0.0-0.10.50.20.70.5-0.30.10.3-0.20.5-0.5-0.80.7-0.01.00.2-1.1
Condit. Reinf. lever presses0.10.20.4-0.30.40.3-0.4-0.50.3-0.2-0.5-0.7-0.4-0.50.50.50.6-0.2-0.30.60.30.1-0.6-0.4-0.1-0.0
Condit. Reinf. lever reinforcers received0.10.11.00.2-0.1-0.40.30.1-0.40.40.1-0.20.20.10.1-0.10.20.6-0.30.2-0.50.1-0.2-0.01.0-0.0
Conditioned reinforcement - actives0.00.00.10.3-0.3-0.20.30.1-0.20.10.10.10.30.2-0.3-0.2-0.10.2-0.1-0.2-0.40.1-0.10.2-0.3-0.1
Conditioned reinforcement - inactives0.00.10.5-0.10.00.0-0.1-0.2-0.1-0.3-0.4-0.4-0.2-0.30.20.10.1-0.1-0.70.30.00.2-0.5-0.4-0.40.4
Conditioned locomotion0.10.20.6-0.20.50.0-0.4-0.4-0.10.4-0.5-0.8-0.4-0.60.80.30.4-0.1-0.40.70.5-0.2-0.3-0.7-0.40.1
Patch foraging indifference point 0 sec0.30.76.3-0.60.7-0.30.20.0-0.30.4-0.6-0.6-0.7-0.31.00.20.30.9-1.60.9-0.4-0.1-0.1-0.92.51.3
Patch foraging indifference point AUC0.71.73.51.9-1.5-1.51.61.5-1.41.41.41.31.61.5-1.1-1.5-1.41.21.5-1.2-0.7-0.80.61.1-0.2-0.9
Delay disc. indifference point, 0s delay0.40.41.90.6-0.5-0.90.80.6-0.91.40.20.10.10.2-0.2-0.5-0.41.20.30.10.4-1.20.0-0.3-0.70.2
Delay disc. indifference point, 16s delay0.40.51.8-0.80.91.1-0.9-0.71.1-1.1-0.2-0.3-0.1-0.50.50.70.7-1.30.10.10.10.8-0.30.2-1.1-0.7
Delay disc. indifference point, 2s delay0.80.91.7-1.10.51.0-1.2-1.21.0-1.0-1.1-0.5-1.2-1.2-0.11.00.9-1.0-0.60.91.3-0.1-0.4-0.91.01.0
Delay disc. indifference point, 24s delay0.20.41.6-0.80.90.5-0.4-0.30.6-0.6-0.6-0.4-0.5-0.70.70.40.3-0.3-1.30.70.10.3-0.0-0.80.81.0
Delay disc. indifference point, 4s delay0.60.73.70.1-0.5-0.3-0.3-0.3-0.20.8-0.50.1-0.7-0.7-0.70.10.20.10.40.71.9-1.80.3-0.91.51.1
Delay disc. indifference point, 8s delay0.40.61.8-0.91.10.5-0.9-0.60.5-0.1-0.7-0.6-0.8-1.20.70.70.5-0.6-0.51.11.4-0.80.2-1.10.21.0
Indifference point function ln k1.13.55.5-2.32.31.5-2.0-1.91.5-1.0-2.2-2.1-2.3-2.32.11.91.9-1.0-2.32.31.20.4-1.0-2.11.41.7
Indifference point function log k1.13.55.5-2.32.31.5-2.0-1.91.5-1.0-2.2-2.1-2.3-2.32.11.91.9-1.0-2.32.31.20.4-1.0-2.11.41.7
Patch foraging total patch changes 0 sec0.30.85.9-0.81.10.1-0.1-0.30.1-0.0-0.7-0.8-0.8-0.51.30.60.70.6-1.71.0-0.40.3-0.4-0.92.41.1
Patch foraging total patch changes 12 sec1.62.13.81.6-1.0-1.91.61.9-1.91.91.41.41.31.3-0.8-1.8-1.91.60.5-0.8-1.0-1.12.00.51.60.4
Patch foraging total patch changes 18 sec1.43.46.22.3-1.8-2.52.22.2-2.52.41.91.71.91.8-1.3-2.1-1.92.21.3-1.2-1.1-1.41.70.92.1-0.2
Patch foraging total patch changes 24 sec0.41.53.61.4-1.2-1.81.61.5-1.81.90.80.90.71.0-0.7-1.5-1.41.90.1-0.5-0.4-1.31.00.11.00.8
Patch foraging total patch changes 6 sec0.40.61.80.9-0.8-0.90.90.9-0.80.80.90.80.70.8-0.8-0.7-0.70.80.7-0.6-0.3-0.60.70.61.3-0.2
Patch foraging time to switch 0 sec0.10.41.20.6-0.7-0.50.40.7-0.40.20.91.00.80.7-1.1-0.7-0.80.10.8-0.8-0.4-0.21.10.7-0.1-0.2
Patch foraging water rate 0 sec0.10.20.9-0.20.40.20.1-0.20.1-0.3-0.2-0.6-0.10.00.70.50.60.3-0.60.1-0.70.8-1.00.00.1-0.4
Patch foraging water rate 12 sec0.51.95.1-1.21.30.8-1.7-1.50.8-0.2-1.7-1.6-1.8-1.91.31.41.3-1.0-0.82.02.2-0.8-0.8-1.90.41.0
Patch foraging water rate 18 sec0.92.05.8-0.60.6-0.2-0.9-0.9-0.20.9-1.8-1.5-1.9-1.91.10.70.80.3-1.52.12.3-1.8-0.6-2.41.42.3
Patch foraging water rate 24 sec1.11.63.7-1.11.30.5-1.2-1.10.40.2-1.6-1.5-1.8-1.71.41.00.9-0.3-1.51.81.7-0.8-0.5-1.90.81.7
Patch foraging water rate 6 sec1.92.95.52.2-2.2-2.31.91.8-2.32.31.61.51.61.6-1.7-1.9-1.61.81.7-1.4-0.4-1.61.31.1-0.0-0.6
Seeking ratio, delayed vs. immediate footshock1.21.74.0-1.81.61.7-2.0-1.61.7-1.0-1.0-1.0-1.2-1.41.01.81.4-2.00.21.01.50.2-0.1-0.5-0.2-0.3
Distance traveled before self-admin0.51.12.6-1.20.61.3-1.1-1.41.0-1.6-1.3-0.9-1.2-1.10.31.31.3-1.0-1.10.80.40.9-1.4-0.60.80.6
Distance traveled after self-admin0.50.81.7-0.80.51.0-1.2-1.30.6-1.3-1.1-1.0-0.9-1.00.51.01.0-1.2-0.60.70.70.8-1.2-0.6-0.00.2
Extensor digitorum longus weight0.20.74.6-0.0-0.10.40.40.30.3-1.00.70.40.90.9-0.2-0.1-0.1-0.2-0.0-1.1-2.11.8-0.11.3-1.0-1.2
Bone: elastic displacement0.81.02.9-1.01.30.5-0.8-0.80.4-0.0-1.1-1.3-1.1-1.11.70.70.8-0.0-1.51.40.10.5-0.6-1.31.10.9
Bone: elastic work1.11.43.9-1.41.81.2-1.1-1.21.2-0.9-1.0-1.5-0.8-1.02.01.31.4-0.8-1.31.1-0.61.6-0.9-0.80.5-0.1
Bone: endosteal estimation0.81.93.31.5-1.3-1.21.61.6-1.31.01.81.41.81.8-1.1-1.4-1.31.01.4-1.7-1.60.01.01.6-1.0-1.4
Bone: endosteal perimeter1.02.55.61.5-1.5-2.12.22.1-2.11.71.41.41.41.7-1.1-1.9-1.82.4-0.1-1.1-2.2-0.51.30.71.40.6
Epididymis fat weight0.10.41.50.40.1-0.60.70.7-0.50.40.30.30.50.40.3-0.6-0.70.8-0.80.1-1.20.30.5-0.31.20.6
Delta time in closed arm before/after self-admin0.60.61.1-1.00.80.9-0.9-0.80.8-0.9-0.8-0.4-0.8-1.00.20.90.5-0.8-0.90.90.80.00.1-0.80.71.0
Delta time in open arm before/after self-admin3.33.97.02.2-1.7-1.92.52.4-1.81.72.41.82.62.6-1.2-2.2-1.92.01.6-2.3-2.50.11.22.2-1.2-1.8
Diff in mean of infusions in LGA sessions0.30.61.00.8-0.7-0.60.70.8-0.60.51.01.00.90.9-0.9-0.7-0.80.50.9-0.9-0.5-0.30.80.90.5-0.5
Delay discount exponential model param0.40.52.10.6-0.4-0.30.80.5-0.40.10.60.20.71.0-0.0-0.5-0.30.60.3-0.9-1.50.9-0.30.9-0.9-1.1
Extinction: sum of active levers before priming2.23.36.1-2.32.51.9-2.3-2.02.0-0.8-1.8-1.9-2.1-2.22.02.21.9-1.7-0.92.22.0-0.2-0.7-1.8-0.20.6
Active lever presses in extinction session 61.91.94.4-1.01.10.5-1.1-1.10.4-0.0-1.7-1.5-1.7-1.81.50.91.0-0.4-1.72.01.7-0.7-0.8-2.11.91.9
Bone: final force0.40.72.70.8-0.6-0.51.00.8-0.50.31.00.71.11.2-0.6-0.6-0.40.70.4-1.0-1.70.60.21.10.3-0.9
Bone: final moment0.30.52.40.6-0.4-0.50.90.7-0.50.30.90.61.01.0-0.4-0.6-0.30.60.4-0.8-1.60.60.30.90.4-0.9
Food consumed during 24 hour testing period4.28.412.13.5-3.3-3.03.13.3-3.02.83.43.23.33.3-3.1-3.2-3.22.13.5-3.1-1.4-1.82.62.8-1.1-1.8
Glucose0.20.43.10.20.3-0.00.70.4-0.0-0.20.3-0.10.50.70.6-0.20.10.7-0.4-0.3-1.81.2-0.70.30.0-0.7
Heart weight1.01.66.1-1.31.31.3-2.1-1.51.3-0.8-1.0-0.6-1.2-1.70.41.40.8-2.10.21.32.5-0.70.6-1.10.70.7
Delay discount hyperbolic model param0.40.62.80.6-0.4-0.30.80.5-0.3-0.00.60.20.81.10.1-0.5-0.30.60.2-0.9-1.71.2-0.51.0-0.9-1.2
Intermittent access intake day 1-15 change0.42.34.41.9-1.9-2.11.71.8-2.11.91.21.51.11.1-1.6-2.0-1.91.80.8-0.8-0.1-1.61.60.20.30.8
Intermittent access intake escalation0.31.42.81.5-1.4-1.61.21.4-1.71.61.01.20.80.8-1.2-1.6-1.61.30.7-0.60.0-1.41.40.10.10.6
Intermittent access intake escalation 20.91.53.21.6-1.4-1.81.31.5-1.71.81.01.10.90.9-1.0-1.7-1.61.40.8-0.7-0.0-1.41.30.2-0.30.4
Intermitt. access day 1 inactive lever presses0.10.71.7-0.10.3-0.50.2-0.1-0.50.9-1.0-1.1-0.9-0.61.00.00.31.0-1.31.00.7-1.0-1.0-1.30.41.2
Intermitt. access day 15 inactive lever presses0.10.51.3-0.50.70.7-0.5-0.70.7-0.9-0.5-0.9-0.2-0.30.90.60.8-0.7-0.60.1-0.41.2-1.10.1-1.1-0.6
Intermitt. access escalation Index0.31.01.9-1.01.20.7-1.2-1.00.80.0-1.1-1.1-1.3-1.31.31.00.9-0.7-0.51.41.4-0.4-0.3-1.30.10.5
Intermittent access day 1 total infusions0.72.03.3-1.71.71.8-1.5-1.71.7-1.7-1.2-1.7-1.0-1.11.51.81.8-1.6-0.90.80.01.6-1.7-0.3-1.6-0.8
Intermittent access day 15 total infusions0.20.51.1-0.80.70.7-0.8-0.80.6-0.8-0.8-0.8-0.7-0.70.50.80.7-0.8-0.60.60.40.5-0.6-0.5-1.10.2
Intermittent access terminal intake (last 3 days)0.30.61.4-0.80.70.7-0.6-0.80.7-0.9-0.9-1.0-0.6-0.70.80.80.8-0.6-0.90.60.10.7-1.1-0.5-1.20.1
Intermittent access total infusions0.60.81.8-1.00.91.0-0.8-1.00.9-1.1-0.8-1.1-0.5-0.60.91.01.0-0.9-0.70.5-0.11.1-1.2-0.2-1.3-0.4
Intermittent access day 1 locomotion1.22.24.9-1.72.11.6-1.7-1.71.6-0.8-1.4-2.0-1.3-1.52.21.81.8-1.4-0.71.40.80.7-1.3-1.0-1.5-0.6
Intermittent access day 15 total locomotion0.20.93.6-0.80.91.1-0.8-0.91.1-1.1-0.4-0.9-0.2-0.40.80.91.0-1.1-0.20.1-0.41.4-1.00.2-1.9-1.1
Intermittent access total locomotion1.21.44.5-1.21.41.5-1.1-1.21.5-1.3-0.5-1.2-0.3-0.51.31.21.3-1.5-0.10.2-0.41.7-1.20.3-2.1-1.5
Intermittent access standard deviation0.10.61.61.0-1.0-1.20.80.8-1.31.00.20.50.30.3-0.7-1.0-1.01.0-0.2-0.00.2-1.00.6-0.30.91.0
Left kidney weight0.75.28.62.6-2.4-2.82.52.7-2.92.12.22.72.12.1-2.6-2.8-2.92.30.9-1.6-1.5-1.52.91.02.60.9
Right kidney weight0.85.48.42.4-2.2-2.62.62.9-2.61.92.62.82.52.5-2.3-2.8-2.92.20.9-2.2-2.6-0.62.91.72.00.2
Cocaine induced anxiety0.41.22.3-1.11.10.6-0.9-1.00.6-0.3-1.5-1.4-1.4-1.41.31.01.0-0.3-1.41.51.1-0.3-1.1-1.50.51.2
Post-drug Anxiety0.40.40.7-0.70.60.7-0.8-0.80.5-0.7-0.7-0.5-0.7-0.80.40.70.7-0.7-0.60.70.50.2-0.4-0.60.70.5
Baseline Anxiety0.61.02.50.7-1.0-0.20.50.7-0.3-0.31.41.61.21.1-1.6-0.7-0.8-0.31.4-1.4-0.90.61.21.40.5-0.9
Tail length1.47.314.53.5-3.5-3.83.43.3-3.73.52.02.31.92.3-2.7-3.4-3.43.71.1-1.6-0.6-2.91.80.60.51.2
Length with tail1.04.69.32.6-2.4-2.73.12.8-2.62.01.82.12.02.3-1.9-2.8-2.83.00.2-1.7-2.2-0.91.30.90.70.7
Length without tail0.10.86.20.50.0-0.20.90.8-0.1-0.40.80.51.21.10.2-0.7-0.50.5-0.4-0.8-2.51.60.00.80.5-0.7
Times rat made contact with spout0.10.10.80.1-0.00.0-0.3-0.10.00.20.10.1-0.0-0.2-0.2-0.0-0.2-0.50.7-0.00.9-0.60.4-0.0-0.9-0.2
Lifetime Intake0.50.61.6-0.80.80.8-0.6-0.80.6-0.9-0.8-1.1-0.5-0.60.90.80.9-0.6-0.90.5-0.20.9-1.2-0.3-1.0-0.2
Liver weight, left0.30.62.70.7-0.4-1.01.31.0-1.01.00.30.20.40.70.1-1.0-0.71.6-0.6-0.2-1.2-0.2-0.1-0.10.40.4
Liver weight, right0.61.14.71.0-0.5-1.51.61.3-1.51.70.50.30.50.90.3-1.3-0.92.2-0.7-0.1-1.4-0.50.3-0.21.20.6
Locomotor activity0.60.95.90.4-0.10.20.10.20.2-0.21.20.61.31.0-0.20.00.2-0.61.7-1.2-1.11.00.41.7-0.8-2.4
Locomotor testing distance0.40.95.80.3-0.30.30.00.00.3-0.41.10.51.11.0-0.40.20.3-0.71.6-1.3-1.01.10.11.8-1.2-2.4
Locomotor testing rearing0.83.17.21.8-1.7-1.51.21.6-1.51.32.42.22.31.9-2.2-1.6-1.60.32.7-2.1-0.8-0.72.32.20.1-1.6
Locomotion in novel chamber0.60.83.80.10.20.4-0.10.20.5-0.31.20.81.10.8-0.30.0-0.1-0.91.6-1.2-0.80.80.91.5-0.6-2.0
Locomotion in novel chamber post-restriction0.10.42.10.6-0.1-0.60.50.2-0.81.4-0.1-0.7-0.20.20.9-0.20.21.00.40.20.1-0.7-0.7-0.1-0.8-0.7
Fecal boli incidents, locomotor time 10.82.25.41.5-1.9-1.82.01.6-1.81.10.91.50.91.4-1.7-1.7-1.42.3-0.4-0.9-1.5-0.50.70.42.31.1
Change in fecal boli incidents, locomotor task0.70.75.0-0.10.3-0.3-0.6-0.3-0.31.1-0.5-0.4-0.8-0.90.30.2-0.0-0.20.50.92.2-2.00.5-1.00.20.8
Time >=10cm from walls, locomotor time 10.30.42.50.4-1.0-0.1-0.2-0.0-0.1-0.30.30.80.20.2-1.6-0.1-0.3-0.51.1-0.50.7-0.50.60.6-0.1-0.1
Bouts of movement, locomotor time 10.30.41.2-0.50.40.4-0.6-0.60.3-0.4-0.9-0.7-0.8-1.00.40.50.4-0.2-0.91.00.9-0.3-0.6-1.0-0.21.1
Total resting periods, locomotor time 10.80.92.1-0.80.80.6-0.9-0.90.5-0.5-1.3-1.0-1.2-1.40.70.80.7-0.4-1.31.41.2-0.3-0.7-1.40.01.5
Rest time, locomotor task time 10.50.72.6-0.90.90.6-0.6-0.70.5-0.6-1.1-1.0-1.0-1.01.00.70.6-0.2-1.61.10.30.3-0.6-1.10.61.3
Distance moved, locomotor task time 10.30.75.20.3-0.00.30.00.10.4-0.20.80.30.80.6-0.0-0.0-0.1-0.71.3-0.9-0.60.80.11.1-2.3-1.9
Vertical activity count, locomotor time 10.64.38.12.3-2.6-1.72.12.1-1.70.72.62.72.62.5-2.8-2.1-2.11.02.4-2.7-1.8-0.11.62.4-0.3-1.6
Time >=10cm from walls, locomotor time 20.30.82.7-0.80.41.2-0.6-1.01.3-1.6-0.7-0.7-0.5-0.40.21.01.1-0.7-0.50.2-0.31.3-1.60.1-1.2-0.5
Bouts of movement, locomotor time 20.20.82.7-0.80.60.9-1.3-1.11.0-0.6-0.9-0.7-0.9-1.20.21.00.9-1.3-0.00.81.6-0.4-0.3-0.8-0.20.4
Total resting periods, locomotor time 20.10.31.5-0.40.10.5-0.9-0.70.6-0.5-0.5-0.2-0.5-0.7-0.20.60.4-1.00.30.31.2-0.4-0.0-0.4-0.30.2
Rest time, locomotor task time 20.20.30.80.7-0.8-0.60.50.6-0.60.40.60.80.50.7-0.9-0.6-0.70.40.6-0.6-0.1-0.50.60.60.30.0
Distance moved, locomotor task time 21.31.74.3-1.41.51.7-1.2-1.31.7-1.8-0.8-1.3-0.5-0.81.41.41.5-1.5-0.70.5-0.52.1-1.5-0.0-1.8-1.0
Vertical activity count, locomotor time 20.81.84.31.3-1.2-1.01.51.5-1.10.31.81.62.11.6-1.3-1.4-1.20.61.1-1.7-1.90.70.91.6-0.8-1.3
Light reinforcement 14.319.428.25.2-5.0-5.25.35.3-5.24.54.84.94.75.0-4.5-5.2-4.94.53.5-4.2-3.3-2.44.13.41.2-1.2
Light reinforcement 25.612.720.44.4-4.5-4.04.54.2-4.13.33.83.83.94.2-3.8-4.2-3.93.82.6-3.7-3.0-1.42.43.00.3-1.2
Bone: marrow area0.82.03.41.5-1.3-1.21.61.6-1.20.91.81.41.91.8-1.2-1.4-1.30.91.4-1.8-1.60.01.01.7-0.9-1.4
Bone: maximum diameter0.30.51.70.10.1-0.70.70.7-0.80.60.10.10.10.20.3-0.7-0.61.3-1.20.2-1.30.10.5-0.51.21.2
Bone: maximum force0.20.43.00.4-0.1-0.30.90.6-0.30.10.70.30.80.90.1-0.4-0.20.7-0.0-0.6-1.70.9-0.20.7-0.0-0.8
Bone: maximum moment0.20.32.70.30.0-0.30.70.5-0.30.20.60.20.70.80.2-0.4-0.10.6-0.1-0.5-1.70.9-0.10.60.0-0.7
Mean time between licks in bursts0.00.31.80.10.3-0.5-0.10.3-0.51.00.20.2-0.0-0.20.3-0.6-0.60.00.20.30.4-0.81.4-0.41.00.5
Mean num. licks in bursts0.30.92.3-0.90.50.8-0.8-1.10.8-0.7-1.3-1.2-1.3-1.10.61.11.1-0.4-0.91.01.20.0-1.5-0.9-0.30.6
Cd content in liver1.11.23.6-1.71.81.4-1.7-1.11.3-1.3-0.6-0.5-0.7-1.11.01.00.7-1.9-0.80.70.11.20.8-0.40.70.3
Co content in liver4.04.67.9-2.62.81.8-2.4-2.21.8-1.3-2.5-2.4-2.5-2.62.82.11.9-1.4-2.72.81.30.9-1.0-2.61.41.8
Cu content in liver0.20.31.2-0.50.90.3-0.4-0.20.3-0.4-0.1-0.3-0.0-0.20.90.30.3-0.3-0.60.4-0.90.90.3-0.31.10.0
Fe content in liver1.01.24.4-0.20.2-0.20.3-0.3-0.10.3-1.4-1.2-1.5-0.91.00.30.61.4-1.71.70.7-0.6-1.8-2.11.21.7
K content in liver1.31.35.4-1.11.70.9-0.8-1.00.9-0.3-1.0-1.7-1.0-0.92.31.21.5-0.3-1.01.3-0.21.0-1.4-1.1-0.2-0.5
Mg content in liver1.31.45.6-1.11.60.5-0.6-0.90.50.1-1.2-1.8-1.1-1.02.41.11.50.3-1.51.7-0.20.6-1.4-1.41.00.2
Mn content in liver0.60.71.80.7-0.4-1.00.81.0-1.11.10.80.70.90.7-0.2-0.9-0.90.90.1-0.5-1.2-0.31.20.41.40.1
Na content in liver0.10.10.80.3-0.2-0.10.40.1-0.10.2-0.0-0.2-0.00.30.2-0.00.20.50.2-0.0-0.1-0.0-0.9-0.0-0.7-0.5
Rb content in liver0.20.20.70.4-0.1-0.60.40.5-0.60.80.30.20.40.30.2-0.5-0.40.50.10.1-0.2-0.40.5-0.20.90.1
Se content in liver1.21.56.20.30.0-0.91.20.5-0.90.8-0.7-0.7-0.7-0.01.0-0.30.02.4-2.21.2-1.2-0.1-1.3-1.62.51.7
Sr content in liver0.50.41.0-0.91.00.7-0.7-0.60.7-0.5-0.4-0.8-0.4-0.50.90.80.8-0.6-0.80.3-0.40.9-0.20.10.6-0.1
Zn content in liver0.91.01.8-1.41.31.1-1.1-1.11.1-1.2-0.9-1.0-0.8-0.91.11.31.3-0.9-1.10.8-0.21.2-0.6-0.60.80.2
Bone: minimum diameter1.52.84.71.9-1.8-1.92.22.1-1.91.71.81.81.92.0-1.6-2.0-1.81.91.1-1.6-1.7-0.81.41.30.4-0.5
Time in familiar zone, hab. session 10.50.52.10.5-0.7-0.70.10.5-0.70.70.30.90.2-0.0-1.0-0.7-0.90.10.5-0.10.9-1.41.5-0.20.80.9
Time in novel zone, hab. session 11.21.33.1-1.00.81.4-1.2-1.41.5-1.3-0.9-1.3-0.8-0.80.91.51.6-1.3-0.00.50.80.9-1.8-0.1-1.6-1.0
Total zone transitions, hab. session 10.60.82.11.1-0.8-0.60.80.8-0.60.51.21.01.21.1-0.8-0.7-0.80.21.4-1.1-0.5-0.10.61.3-0.6-1.2
Total locomotion distance, hab. session 10.30.42.00.6-0.4-0.30.40.4-0.30.40.80.30.80.7-0.2-0.3-0.3-0.01.2-0.8-0.40.10.11.0-1.2-1.4
Locomotion velocity, hab. session 10.50.82.10.9-0.6-0.70.90.8-0.70.71.10.61.21.1-0.3-0.6-0.60.41.2-1.0-0.90.10.41.3-0.9-1.5
Time in familiar zone, hab. session 21.11.22.31.2-1.1-1.41.11.3-1.41.51.11.21.00.9-1.0-1.4-1.41.10.8-0.6-0.3-1.21.40.40.90.2
Time in novel zone, hab. session 21.82.04.6-1.51.52.0-1.6-1.62.0-2.2-0.8-1.1-0.7-0.91.01.61.5-2.1-0.30.30.11.8-1.10.2-2.1-1.0
Total zone transitions, hab. session 20.91.12.91.3-0.6-1.30.81.1-1.31.71.21.01.30.9-0.5-1.1-1.10.61.4-0.5-0.1-1.21.60.61.0-0.6
Total locomotion distance, hab. session 20.70.91.91.1-0.5-1.01.01.1-1.01.01.30.81.41.2-0.3-0.9-0.80.61.0-0.9-1.2-0.00.91.10.1-1.1
Locomotion velocity, hab. session 20.81.02.01.1-0.7-1.01.21.1-1.11.01.30.91.41.3-0.4-1.0-0.80.81.0-0.9-1.40.10.81.10.3-1.1
Novel to familiar place preference ratio0.50.73.7-0.60.51.0-1.0-0.81.0-0.8-0.0-0.3-0.1-0.30.20.70.6-1.50.8-0.20.60.6-0.10.5-1.9-1.2
Novelty place preference0.60.85.5-0.50.31.0-0.9-0.71.0-0.90.2-0.10.1-0.1-0.00.60.5-1.51.1-0.60.40.7-0.10.8-2.3-1.5
Time in novel zone, NPP test0.91.16.3-0.90.61.3-1.3-1.11.3-1.1-0.3-0.6-0.3-0.50.41.11.0-1.80.9-0.10.90.7-0.60.4-2.5-1.4
Total zone transitions, NPP test1.31.93.11.5-0.7-1.71.61.8-1.71.61.51.31.61.5-0.4-1.6-1.61.50.7-0.8-1.6-0.41.50.71.6-0.3
Total locomotion distance, NPP test0.20.30.70.6-0.0-0.70.60.7-0.70.80.70.40.80.60.2-0.6-0.60.40.5-0.3-0.7-0.10.70.40.2-0.6
Locomotion velocity, NPP test0.60.92.70.9-0.2-1.11.11.3-1.11.01.20.81.21.10.1-1.2-1.11.00.3-0.6-1.60.21.10.70.7-0.5
Intraocular pressure1.82.94.9-2.22.12.0-2.2-2.01.9-1.8-1.9-1.7-1.9-2.01.62.01.8-1.8-1.61.71.30.9-1.0-1.30.10.8
Delta distance traveled before/after self-admin0.10.10.50.4-0.0-0.40.20.3-0.40.70.4-0.00.40.20.2-0.3-0.20.10.6-0.10.1-0.30.30.1-0.5-0.6
Delta ambulatory time before/after self-admin0.30.62.51.0-0.6-1.10.60.8-1.21.60.70.40.60.4-0.2-0.9-0.80.60.9-0.20.4-1.10.90.0-0.2-0.2
Parametrial fat weight0.61.54.11.4-1.1-1.21.61.5-1.20.71.41.21.51.5-1.0-1.5-1.51.20.2-1.3-2.00.50.91.2-0.0-0.3
Pavlov. Cond. lever latency0.40.62.30.4-0.5-0.0-0.10.3-0.0-0.00.90.90.90.6-0.9-0.3-0.3-0.81.5-1.00.0-0.21.11.0-1.0-1.1
Pavlov. Cond. magazine entry latency0.91.22.5-1.10.90.9-1.0-1.20.9-0.6-1.5-1.5-1.6-1.31.11.11.1-0.4-1.21.21.20.1-1.4-1.1-0.20.7
Pavlov. Cond. change in total contacts0.50.51.90.00.0-0.50.40.1-0.60.9-0.7-0.7-0.8-0.50.6-0.20.01.3-1.30.90.2-0.6-0.6-1.01.21.4
Pavlov. Cond. index score1.01.33.2-1.11.10.6-0.7-1.00.6-0.3-1.6-1.6-1.6-1.31.50.90.90.1-1.81.50.60.2-1.4-1.40.41.2
Pavlov. Cond. latency score0.50.72.3-0.70.80.3-0.3-0.50.3-0.1-1.1-1.1-1.1-0.91.20.50.50.4-1.51.10.20.2-1.0-1.00.51.0
Pavlov. Cond. lever contacts0.91.03.0-0.80.90.5-0.4-0.80.5-0.3-1.4-1.5-1.3-1.01.30.80.90.4-1.71.30.40.3-1.6-1.20.51.1
Pavlov. Cond. magazine entry number2.02.64.81.7-1.6-1.41.41.7-1.41.02.12.22.21.8-1.9-1.7-1.80.52.0-1.8-1.1-0.72.11.50.1-1.0
Pavlov. Cond. intertrial magazine entries0.91.07.9-0.40.4-0.60.50.4-0.50.5-0.5-0.2-0.4-0.30.7-0.3-0.11.4-1.91.1-0.9-0.20.2-1.52.81.9
Pavlov. Cond. lever-magazine prob. diff.1.41.84.2-1.31.31.0-0.9-1.20.9-0.6-1.8-1.9-1.8-1.51.91.21.2-0.0-2.01.60.50.6-1.8-1.40.11.1
Pavlov. Cond. response bias1.92.44.8-1.51.31.1-1.2-1.61.1-0.6-2.2-2.1-2.2-1.81.71.51.6-0.2-1.92.01.40.1-2.1-1.70.31.3
Pavlov. Cond. lever latency0.10.10.6-0.40.20.4-0.1-0.10.5-0.7-0.00.1-0.00.1-0.00.2-0.0-0.2-0.3-0.3-0.60.8-0.10.3-0.3-0.0
Pavlov. Cond. magazine entry latency0.00.10.30.1-0.0-0.30.10.3-0.30.20.20.30.20.1-0.1-0.3-0.50.1-0.0-0.0-0.1-0.20.5-0.10.30.3
Pavlov. Cond. change in total contacts0.20.41.3-0.20.2-0.1-0.4-0.5-0.10.4-0.7-0.7-0.7-0.80.40.40.50.1-0.41.01.1-0.9-0.3-1.01.20.8
Pavlov. Cond. index score0.10.10.60.1-0.0-0.3-0.1-0.1-0.30.4-0.3-0.3-0.3-0.40.20.00.10.2-0.00.60.8-0.7-0.1-0.70.50.4
Pavlov. Cond. latency score0.10.10.50.2-0.1-0.40.00.0-0.40.6-0.2-0.3-0.2-0.30.2-0.10.00.3-0.10.50.7-0.7-0.1-0.70.40.5
Pavlov. Cond. lever contacts0.10.10.60.5-0.4-0.50.10.2-0.50.60.20.20.20.1-0.2-0.3-0.20.10.60.10.6-0.80.3-0.10.2-0.1
Pavlov. Cond. magazine entry number0.10.10.30.0-0.10.2-0.2-0.10.3-0.20.10.10.10.1-0.30.10.1-0.40.4-0.40.10.10.10.5-0.6-0.5
Pavlov. Cond. intertrial magazine entries1.12.43.61.9-1.8-1.91.71.7-1.91.81.51.71.51.5-1.8-1.8-1.61.51.1-1.2-0.8-1.31.61.01.60.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.6-0.10.2-0.1-0.2-0.2-0.20.4-0.4-0.4-0.4-0.50.40.10.20.1-0.10.70.8-0.6-0.1-0.70.50.4
Pavlov. Cond. response bias0.00.00.10.20.0-0.20.00.0-0.30.3-0.0-0.10.1-0.10.2-0.00.10.10.10.30.2-0.30.0-0.30.4-0.0
Time in closed arm before self-admin0.30.52.60.7-0.8-0.90.30.2-0.91.5-0.2-0.1-0.5-0.1-0.3-0.5-0.20.80.60.31.1-1.60.1-0.70.50.5
Time in closed arm after self-admin0.40.52.9-0.2-0.3-0.1-0.2-0.1-0.10.1-0.50.2-0.8-0.5-0.60.1-0.00.2-0.30.51.1-1.10.4-0.81.71.4
Time in open arm before self-admin0.60.71.8-1.11.01.1-1.1-0.90.9-1.4-0.7-0.4-0.7-1.00.31.00.6-1.3-0.80.80.80.4-0.1-0.70.70.8
Time in open arm after self-admin0.30.32.3-0.10.50.30.10.10.2-0.30.3-0.20.50.40.60.00.1-0.20.0-0.4-0.91.0-0.30.6-1.5-1.0
Bone: periosteal estimation1.02.33.91.6-1.4-1.61.81.9-1.61.31.91.62.01.9-1.3-1.7-1.61.31.1-1.7-2.0-0.11.41.6-0.1-0.9
Bone: periosteal perimeter0.91.73.71.0-0.8-1.71.61.7-1.81.51.21.21.11.2-0.6-1.6-1.51.8-0.3-0.7-1.9-0.31.70.31.70.7
Bone: post-yield work0.50.92.01.0-1.3-0.61.00.8-0.50.31.11.11.11.2-1.4-0.7-0.60.41.2-1.3-0.6-0.20.31.3-0.6-1.0
Progressive ratio test 1 active lever presses0.51.02.6-1.01.11.2-0.8-1.01.1-1.2-0.8-1.2-0.5-0.51.11.11.2-0.9-0.70.4-0.31.3-1.4-0.0-1.6-0.7
Progressive ratio test 1 breakpoint0.61.12.5-1.11.11.3-0.8-1.11.2-1.3-0.8-1.2-0.5-0.61.11.11.2-1.0-0.80.4-0.31.4-1.4-0.1-1.6-0.7
Progressive ratio test 1 inactive lever presses0.30.73.2-0.70.80.6-0.3-0.80.5-0.8-1.0-1.3-0.6-0.51.30.71.0-0.2-1.40.6-0.30.9-1.8-0.5-0.40.1
Progressive ratio test 2 active lever presses0.40.62.0-0.90.71.1-0.7-0.81.0-1.4-0.5-0.6-0.4-0.40.40.90.8-1.0-0.50.1-0.21.2-0.90.1-1.0-0.4
Progressive ratio test 2 breakpoint0.50.72.3-0.90.71.1-0.8-0.91.0-1.5-0.6-0.6-0.4-0.50.40.90.8-1.1-0.50.1-0.21.3-0.90.1-0.9-0.4
Progressive ratio test 2 inactive lever presses0.51.43.3-1.41.21.5-1.3-1.51.4-1.8-1.1-1.3-0.9-1.01.01.41.3-1.5-1.00.70.11.4-1.3-0.4-1.1-0.2
Incentive Sensitization - Responses0.00.10.7-0.2-0.20.3-0.2-0.10.3-0.80.10.40.10.1-0.50.1-0.2-0.50.0-0.3-0.10.50.10.30.00.1
Incentive Sensitization - Breakpoint0.00.10.5-0.1-0.20.2-0.10.00.1-0.70.20.40.10.1-0.6-0.0-0.3-0.40.1-0.4-0.10.40.20.30.10.1
Sum of active levers in priming session hrs 5-60.30.21.30.20.10.10.10.20.10.10.70.40.60.5-0.2-0.1-0.1-0.31.0-0.5-0.40.20.60.8-0.6-1.2
Progressive ratio0.51.63.31.2-1.3-0.91.11.4-0.80.41.71.81.51.6-1.7-1.3-1.50.51.4-1.6-1.0-0.11.61.4-0.2-0.7
Food seeking constrained by brief footshock1.61.94.01.8-1.6-2.01.81.7-2.01.81.11.21.01.3-1.2-1.9-1.72.00.3-0.8-0.9-1.01.20.40.80.6
Seeking ratio, punishment vs. effort0.20.41.60.5-0.4-0.80.70.4-0.90.9-0.3-0.4-0.10.00.4-0.6-0.21.3-0.90.3-0.4-0.3-0.5-0.40.70.7
Retroperitoneal fat weight0.52.29.91.4-0.5-1.31.81.9-1.30.91.71.32.01.8-0.4-1.7-1.71.4-0.2-1.3-3.21.01.51.11.1-0.5
Reaction time number correct0.51.93.3-1.71.51.1-1.5-1.41.0-0.8-1.7-1.6-1.8-1.81.51.41.3-0.8-1.71.71.30.0-0.9-1.8-0.01.4
Reaction time mean minus median0.10.92.3-1.00.81.1-0.7-0.91.1-1.5-1.0-1.0-0.9-0.80.70.70.8-0.7-1.50.5-0.21.3-1.3-0.5-1.10.5
Reaction time mean minus median AUC0.21.73.5-1.41.41.5-1.0-1.31.5-1.8-1.3-1.4-1.2-1.11.41.11.1-1.0-1.90.9-0.31.8-1.6-0.8-1.20.4
Reaction time num false alarms0.50.82.3-1.51.41.2-1.2-0.81.1-1.3-0.4-0.3-0.4-0.70.70.90.6-1.4-0.80.5-0.31.20.6-0.20.90.3
Reaction time num false alarms AUC0.51.12.7-1.61.51.3-1.5-1.11.2-1.2-0.8-0.6-0.9-1.20.81.20.8-1.5-0.90.90.50.60.4-0.71.10.7
Reaction time trials correct on left0.51.93.3-1.71.51.1-1.5-1.41.0-0.8-1.7-1.6-1.8-1.81.51.41.3-0.8-1.71.71.30.0-0.9-1.8-0.01.4
Reaction time trials on left0.61.93.1-1.71.61.2-1.5-1.51.1-0.9-1.7-1.6-1.8-1.81.51.41.4-0.8-1.71.61.20.2-0.9-1.7-0.11.3
Reaction time mean1.53.37.6-2.22.12.5-1.9-2.02.5-2.8-1.6-1.6-1.4-1.51.71.81.8-2.1-1.71.1-0.12.5-1.7-0.7-1.2-0.0
Reaction time mean AUC1.33.26.9-2.12.12.4-1.9-2.02.4-2.6-1.6-1.7-1.4-1.51.71.81.8-2.0-1.61.1-0.12.4-1.7-0.7-1.3-0.1
Median of all reaction times2.23.47.0-2.32.32.5-2.1-2.12.5-2.6-1.6-1.7-1.4-1.61.82.01.9-2.2-1.51.20.12.4-1.6-0.8-0.9-0.1
Reaction time omissions0.60.95.5-1.10.71.4-0.8-0.71.4-2.3-0.20.2-0.2-0.2-0.30.60.5-1.5-0.6-0.4-0.82.0-0.20.6-0.2-0.2
Reaction time false alarm rate0.10.20.9-0.60.60.5-0.6-0.30.5-0.5-0.00.1-0.0-0.30.10.40.1-0.7-0.10.1-0.20.50.60.11.00.1
Reaction time premature initiation rate3.35.111.52.8-2.4-3.22.72.8-3.23.41.91.91.81.9-1.7-2.9-2.82.91.3-1.4-0.5-2.72.00.7-0.30.4
Reaction time premature initiations0.82.36.71.7-1.5-2.31.71.8-2.42.61.01.00.90.9-0.9-1.9-1.82.10.5-0.50.1-2.31.5-0.1-0.20.9
Std. dev. reaction times0.31.13.7-1.10.91.4-0.9-1.01.4-1.9-0.9-0.8-0.8-0.80.60.80.7-1.2-1.20.4-0.21.6-1.2-0.3-1.40.2
Reaction time trials completed0.61.93.1-1.71.61.2-1.5-1.51.1-0.9-1.7-1.6-1.8-1.81.51.41.4-0.8-1.71.61.20.2-0.9-1.7-0.11.3
Reaction time trials AUC0.61.93.0-1.71.61.3-1.5-1.51.2-1.0-1.7-1.6-1.7-1.71.61.51.4-0.9-1.61.61.10.3-1.0-1.6-0.21.2
Run reversals in cocaine runway, females1.11.27.0-0.20.10.70.50.10.6-1.60.70.31.21.0-0.10.10.3-0.3-0.3-1.1-2.52.6-0.71.5-1.3-1.6
Run reversals in cocaine runway, males0.50.52.3-0.5-0.10.9-1.1-0.90.8-1.3-0.50.1-0.6-0.5-0.70.70.5-1.30.30.10.60.6-0.10.11.50.1
Latency to leave start box in cocaine runway0.50.72.60.1-0.10.40.20.20.3-1.20.90.71.10.9-0.5-0.2-0.1-0.80.5-1.2-1.51.60.11.5-0.7-1.4
Latency to leave start box in cocaine runway, F0.60.72.7-0.60.61.1-0.4-0.61.0-1.4-0.0-0.40.10.10.60.80.9-0.90.1-0.4-0.91.7-1.10.9-1.1-1.5
Latency to leave start box in cocaine runway, M1.51.43.21.1-1.1-1.01.11.3-1.00.31.61.61.81.3-1.5-1.5-1.40.30.8-1.4-1.30.21.51.30.1-0.5
Std. dev. time between licks in bursts0.71.33.61.2-1.1-1.41.01.3-1.41.51.21.41.10.9-1.2-1.5-1.50.81.0-0.9-0.2-1.21.90.60.60.2
Total sessions with >9 infusions2.93.78.1-2.02.31.6-1.8-2.01.6-0.9-2.4-2.8-2.1-2.12.82.02.1-1.0-2.12.21.20.5-2.4-1.9-0.90.6
Short access day 1 total inactive lever presses0.30.63.60.00.10.20.5-0.10.1-0.7-0.4-0.90.40.40.70.00.50.4-1.2-0.3-1.41.3-1.90.4-1.3-0.6
Short access day 10 total inactive lever presses0.10.84.40.9-0.4-1.40.90.9-1.32.10.1-0.10.10.20.3-0.9-0.61.7-0.00.40.4-1.60.3-0.60.80.6
Short access day 1 total infusions2.65.211.0-2.32.41.9-1.8-2.31.8-1.7-3.0-3.2-2.5-2.32.92.32.5-1.0-3.22.51.00.9-3.3-2.3-1.11.3
Short access day 10 total infusions0.50.92.3-0.91.20.8-0.8-1.00.7-0.4-1.0-1.5-0.7-0.81.51.01.1-0.6-0.80.90.20.6-1.3-0.6-1.2-0.4
Short access total infusions1.11.63.4-1.31.41.2-1.1-1.31.0-1.1-1.5-1.8-1.1-1.21.71.31.4-0.8-1.61.20.30.9-1.8-1.0-1.00.2
Short access day 1 locomotion2.94.78.8-2.42.62.2-2.0-2.42.1-1.8-2.6-3.0-2.2-2.12.92.42.5-1.4-2.52.10.91.2-2.9-1.7-1.70.5
Short access day 10 total locomotion0.52.15.3-1.62.11.3-1.9-1.61.2-0.1-1.3-1.8-1.6-1.72.31.51.5-1.6-0.21.61.70.0-0.5-1.3-0.8-0.3
Short access total locomotion2.74.19.3-2.32.72.0-2.3-2.31.9-1.0-2.2-2.8-2.1-2.23.12.32.3-1.7-1.52.21.50.7-1.9-1.8-1.3-0.0
One hour access (0.3 mA shock)0.40.52.1-0.70.70.9-0.7-0.70.8-1.0-0.4-0.5-0.3-0.40.40.70.6-1.0-0.20.2-0.00.9-0.5-0.0-1.4-0.5
Compulsive drug intake0.81.23.5-0.50.8-0.1-0.7-0.5-0.20.8-1.2-1.1-1.4-1.31.20.50.50.2-1.01.71.8-1.3-0.2-1.91.21.6
One hour access (shock baseline)0.20.62.6-0.50.10.9-0.3-0.30.8-1.40.40.30.40.3-0.40.40.2-1.00.5-0.8-0.81.4-0.11.0-1.6-1.2
Social response proportion0.30.31.1-0.40.30.6-0.10.00.5-0.90.50.50.40.5-0.10.1-0.0-0.60.3-0.8-0.91.00.40.9-0.6-0.8
Social responses0.40.53.60.20.0-0.2-0.30.4-0.20.41.01.00.80.4-0.6-0.3-0.6-0.81.5-0.70.1-0.31.90.90.1-0.8
Social time0.30.42.10.3-0.5-0.7-0.10.0-0.70.9-0.30.0-0.4-0.5-0.4-0.3-0.30.2-0.00.31.2-1.40.7-0.51.01.1
Soleus weight0.10.20.6-0.1-0.10.2-0.2-0.00.2-0.40.40.50.60.2-0.60.1-0.0-0.70.6-0.6-0.20.30.60.8-0.4-0.5
Bone: stiffness0.71.45.10.9-0.9-0.41.41.1-0.3-0.21.41.11.51.8-0.9-0.7-0.60.70.8-1.6-2.31.1-0.21.7-0.6-1.6
Tibialis anterior weight0.10.41.9-0.80.80.4-0.6-0.50.3-0.6-0.7-0.6-0.6-0.80.70.40.2-0.2-1.40.7-0.20.5-0.0-0.80.41.1
Time to tail flick, vehicle, before self-admin0.30.41.00.6-0.9-0.40.50.5-0.30.20.60.90.40.7-1.0-0.5-0.60.40.9-0.7-0.1-0.40.40.60.7-0.2
Time to tail flick, vehicle, after self-admin0.81.74.71.0-1.5-0.71.01.3-0.70.11.72.21.41.5-2.1-1.1-1.40.31.7-1.8-0.7-0.31.71.50.5-0.6
Time to tail flick, test, before self-admin1.41.65.2-1.31.11.7-1.0-1.21.8-2.2-0.9-1.0-0.5-0.61.01.21.3-1.3-1.30.2-0.82.3-1.60.0-0.7-0.4
Time to tail flick, test, after self-admin0.10.10.40.4-0.4-0.20.10.4-0.0-0.10.50.60.50.3-0.5-0.4-0.6-0.20.4-0.5-0.20.00.60.40.4-0.0
Delta time to tail flick, vehicle, before/after SA0.20.20.50.3-0.5-0.40.50.6-0.4-0.10.50.70.60.5-0.6-0.6-0.60.3-0.1-0.6-0.60.10.60.40.40.3
Delta time to tail flick, test, before/after SA0.20.31.20.3-0.1-0.4-0.20.2-0.40.70.10.2-0.1-0.3-0.2-0.3-0.5-0.10.30.31.0-1.11.0-0.40.70.7
Tibia length0.10.42.1-0.00.1-0.20.60.1-0.10.1-0.5-0.6-0.50.00.70.10.31.2-1.10.5-0.60.3-1.4-0.70.70.5
Ambulatory time before self-admin0.51.43.0-1.31.01.5-1.2-1.51.2-1.7-1.4-1.3-1.1-1.10.81.51.6-1.1-1.30.80.11.3-1.7-0.50.40.2
Ambulatory time after self-admin0.10.10.6-0.10.00.3-0.5-0.6-0.1-0.5-0.5-0.5-0.3-0.40.20.30.5-0.6-0.10.30.30.4-0.7-0.20.1-0.1
Bone: tissue strength1.01.03.2-1.21.40.7-0.6-0.70.7-0.7-1.1-1.1-1.1-0.81.70.70.80.0-1.81.1-0.61.2-0.9-1.30.60.9
Total heroin consumption0.10.10.7-0.00.60.1-0.20.1-0.10.10.50.10.40.20.50.00.0-0.50.6-0.2-0.30.30.60.50.2-0.9
Bone: trabecular number1.52.913.92.0-2.5-2.21.31.1-2.12.60.40.90.30.3-2.1-1.3-1.21.81.3-0.22.4-3.70.7-0.40.71.3
Bone: trabecular spacing1.31.98.0-1.62.11.8-1.2-1.11.8-2.1-0.5-0.9-0.5-0.51.91.11.0-1.6-1.00.4-1.42.8-0.7-0.0-1.2-1.0
Bone: trabecular thickness0.40.61.51.1-1.2-0.80.80.6-0.70.90.60.40.70.7-1.0-0.5-0.40.71.0-0.70.3-1.0-0.10.7-0.8-0.6
Bone: trabecular tissue density1.01.76.1-1.21.11.9-1.0-1.11.9-2.4-0.2-0.5-0.1-0.00.71.31.2-1.80.1-0.2-0.92.5-1.20.8-1.1-1.8
Water consumed over 24 hours0.40.83.01.1-0.9-0.80.50.7-0.81.01.00.81.00.8-0.8-0.7-0.80.11.7-0.80.4-1.00.80.8-1.3-1.1
Number of responses in last shaping day2.02.65.3-1.51.40.9-1.3-1.50.9-0.7-2.3-2.0-2.2-2.01.71.41.3-0.4-2.32.21.7-0.5-1.6-2.30.62.1