Hub : Genes

LOC102553657

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC102553657 0.07 0.04 1.6e-05 0.03 0.06 0.07 0.06 9.3e-04 8.2e-06 2.5e-06 1.7e-05
2 LHb gene expression LOC102553657 0.23 0.17 6.9e-03 0.02 0.08 0.05 0.04 9.7e-02 5.0e-03 2.1e-02 3.2e-02
3 BLA gene expression LOC102553657 0.21 0.11 3.6e-09 0.19 0.16 0.16 0.18 2.5e-10 8.6e-09 6.3e-09 5.4e-10
4 OFC gene expression LOC102553657 0.35 0.17 1.2e-04 0.15 0.15 0.1 0.11 1.7e-04 2.5e-04 2.2e-03 1.6e-03
5 IL gene expression LOC102553657 0.43 0.2 2.6e-05 0.17 0.17 0.18 0.19 6.4e-05 5.4e-05 4.2e-05 2.8e-05
6 PL gene expression LOC102553657 0.25 0.1 0.0e+00 0.26 0.24 0.26 0.26 1.0e-27 1.4e-26 6.6e-28 2.0e-28
7 IC gene expression LOC102553657 0.15 0.08 5.3e-06 0.1 0.08 0.13 0.13 4.8e-05 2.3e-04 3.7e-06 4.4e-06
8 NAcc gene expression LOC102553657 0.17 0.08 0.0e+00 0.18 0.19 0.18 0.19 5.6e-27 1.8e-27 7.7e-27 4.7e-28
9 Brain gene expression LOC102553657 0.35 0.14 0.0e+00 0.27 0.26 0.28 0.27 4.9e-25 3.8e-24 9.8e-26 7.8e-25
10 Liver gene expression LOC102553657 0.45 0.17 0.0e+00 0.32 0.17 0.33 0.13 1.3e-35 7.5e-19 8.4e-38 6.5e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.83.34.92.1-2.21.91.9-1.9-1.91.7-1.81.5-0.7
Area under the delay curve1.01.62.31.2-1.51.51.3-1.3-1.41.2-1.41.20.1
BMI with tail2.69.028.65.3-3.12.12.2-2.2-2.12.0-1.71.6-4.9
BMI without tail0.73.712.83.2-1.61.31.3-1.3-1.31.3-1.21.3-3.6
Body weight3.214.240.46.4-4.02.92.9-2.9-2.92.9-2.52.2-5.7
Weight adjusted by age0.31.05.41.70.1-0.8-0.50.50.5-0.10.30.5-2.3
Bone surface0.30.51.21.1-1.00.70.6-0.6-0.70.7-0.60.3-0.7
Bone volume1.32.55.92.4-2.01.41.5-1.5-1.51.4-1.31.0-1.6
Breakpoint value in progressive ratio session1.52.73.41.5-1.71.71.7-1.7-1.71.8-1.81.70.8
Number of licking bursts0.72.33.01.3-1.71.61.6-1.6-1.61.6-1.71.40.5
Context. condit. distance diff. score1.01.22.2-1.41.5-0.9-0.90.91.0-1.41.1-1.0-0.6
Locomotion velocity, session 10.60.73.4-0.9-0.30.80.7-0.7-0.70.3-0.60.51.8
Locomotion distance, session 10.40.51.6-1.30.7-0.5-0.50.50.6-1.00.7-0.6-0.1
Locomotion velocity, session 22.42.93.9-2.01.6-1.7-1.71.71.7-2.01.8-1.8-0.6
Locomotion distance, session 20.40.52.20.9-0.80.60.6-0.6-0.60.2-0.40.4-1.5
Locomotion velocity, session 30.20.30.6-0.80.5-0.3-0.30.30.4-0.60.2-0.6-0.7
Locomotion distance, session 31.01.12.4-0.91.3-0.8-0.70.70.9-1.50.9-0.7-1.5
Stereotopy head waving bouts, day 30.20.20.60.8-0.50.20.4-0.4-0.30.4-0.50.4-0.1
Stereotopy head waving duration, day 30.40.41.90.0-0.40.40.5-0.5-0.50.7-0.70.71.4
Locomotion velocity, session 70.10.10.10.2-0.30.30.3-0.3-0.30.3-0.40.3-0.2
Locomotion distance, session 70.30.40.8-0.90.6-0.5-0.60.60.6-0.80.6-0.6-0.6
Stereotopy head waving bouts, day 70.10.20.20.4-0.40.50.5-0.5-0.50.4-0.40.30.2
Stereotopy head waving duration, day 70.60.81.11.0-1.00.90.9-0.9-0.91.1-0.90.70.2
Locomotion velocity, session 80.70.92.3-1.50.8-1.0-0.90.90.9-0.90.7-0.90.5
Locomotion distance, session 80.71.02.0-1.41.1-0.8-0.80.80.9-1.31.0-0.9-0.9
Degree of sensitization distance0.60.62.7-0.0-0.80.60.5-0.5-0.60.9-0.60.41.6
Degree of sensitization stereotypy0.50.50.70.6-0.70.80.8-0.8-0.80.8-0.70.60.3
Conditioned locomotion0.00.00.1-0.30.1-0.1-0.10.10.1-0.20.2-0.2-0.3
Cocaine response after cond. corrected1.32.03.2-1.71.8-1.6-1.61.61.5-1.21.2-0.80.3
Cocaine response after cond. not corrected1.52.13.8-1.91.8-1.6-1.61.61.5-1.21.2-0.90.9
Cocaine response before conditioning0.20.31.40.1-0.50.50.4-0.4-0.40.4-0.40.21.2
Saline control response0.70.92.0-1.41.0-0.9-0.80.80.9-1.21.1-0.80.4
Bone: connectivity density0.00.00.1-0.2-0.20.20.2-0.2-0.20.1-0.20.10.1
Bone: cortical apparent density5.48.611.0-3.03.3-3.0-3.13.13.1-3.33.2-2.6-0.7
Bone: cortical area3.35.39.93.1-2.62.32.2-2.2-2.32.3-2.11.9-1.7
Bone: cortical porosity0.91.01.60.4-1.01.31.2-1.2-1.21.0-1.20.70.4
Bone: cortical porosity2.12.33.21.1-1.51.81.7-1.7-1.71.6-1.71.20.3
Bone: cortical thickness0.91.53.71.7-1.31.01.0-1.0-1.01.0-0.90.7-1.9
Bone: cortical thickness0.30.42.90.9-0.50.20.2-0.2-0.20.00.1-0.1-1.7
Bone: cortical tissue density5.48.611.0-3.13.3-3.0-3.13.13.1-3.33.2-2.6-0.6
Condit. Reinf. active minus inactive responses0.50.61.5-0.20.20.90.9-0.9-0.80.3-0.71.20.7
Condit. Reinf. active-inactive response ratio0.30.30.9-0.50.40.60.5-0.5-0.50.0-0.40.90.9
Condit. Reinf. active responses1.51.93.40.9-0.71.71.7-1.7-1.61.0-1.51.90.3
Condit. Reinf. inactive responses2.02.53.41.5-1.41.91.8-1.8-1.81.4-1.71.7-0.0
Incentive salience index mean0.40.51.5-0.50.40.70.6-0.6-0.60.2-0.61.21.2
Condit. Reinf. lever presses0.30.41.8-0.40.10.50.5-0.5-0.50.3-0.50.91.3
Condit. Reinf. active minus inactive responses3.85.88.91.0-1.62.62.6-2.6-2.62.5-2.73.02.4
Condit. Reinf. active-inactive response ratio1.62.64.90.2-0.61.61.7-1.7-1.61.6-1.82.12.2
Condit. Reinf. active responses5.07.110.21.7-2.22.82.9-2.9-2.82.9-3.03.21.9
Condit. Reinf. inactive responses1.32.02.61.3-1.51.41.4-1.4-1.51.6-1.61.50.3
Condit. Reinf. lever presses2.43.44.41.2-1.62.02.1-2.1-2.11.9-1.92.01.5
Condit. Reinf. lever reinforcers received4.66.59.61.5-2.02.72.8-2.8-2.72.7-2.83.11.9
Conditioned reinforcement - actives0.20.81.30.4-0.71.01.1-1.1-1.00.8-1.01.00.8
Conditioned reinforcement - inactives0.51.31.61.3-1.01.21.2-1.2-1.21.2-1.21.3-0.0
Conditioned locomotion0.30.41.1-0.40.1-0.7-0.60.60.6-0.80.7-1.0-0.4
Patch foraging indifference point 0 sec0.61.63.82.0-1.21.21.1-1.1-1.11.0-0.91.0-1.7
Patch foraging indifference point AUC1.53.55.41.9-2.32.01.9-1.9-2.02.0-2.01.40.6
Delay disc. indifference point, 0s delay0.50.51.11.0-1.00.60.6-0.6-0.60.6-0.50.0-1.0
Delay disc. indifference point, 16s delay0.81.21.70.7-1.31.31.1-1.1-1.21.2-1.21.00.7
Delay disc. indifference point, 2s delay0.00.00.10.0-0.30.20.0-0.0-0.1-0.10.0-0.4-0.3
Delay disc. indifference point, 24s delay2.33.75.31.7-2.32.12.0-2.0-2.12.0-2.11.91.0
Delay disc. indifference point, 4s delay0.50.50.80.3-0.50.90.7-0.7-0.80.7-0.90.80.2
Delay disc. indifference point, 8s delay1.93.24.92.1-2.21.91.8-1.8-1.91.7-1.91.7-0.3
Indifference point function ln k0.30.91.9-1.41.1-1.1-1.01.01.0-0.90.9-0.6-0.2
Indifference point function log k0.30.91.9-1.41.1-1.1-1.01.01.0-0.90.9-0.6-0.2
Patch foraging total patch changes 0 sec0.72.14.62.1-1.51.51.4-1.4-1.41.3-1.11.2-1.5
Patch foraging total patch changes 12 sec2.12.94.21.7-1.92.01.9-1.9-1.91.6-1.71.4-0.3
Patch foraging total patch changes 18 sec3.07.19.72.9-3.13.02.8-2.8-2.92.7-2.72.2-0.3
Patch foraging total patch changes 24 sec2.27.48.92.7-2.83.02.9-2.9-2.93.0-3.02.50.4
Patch foraging total patch changes 6 sec2.23.76.92.6-2.22.11.8-1.8-1.91.7-1.61.5-1.5
Patch foraging time to switch 0 sec0.41.52.9-1.71.5-1.2-1.31.31.2-1.21.1-1.00.2
Patch foraging water rate 0 sec0.20.91.61.3-1.11.11.1-1.1-1.00.7-0.70.7-0.7
Patch foraging water rate 12 sec0.31.12.01.4-1.21.11.1-1.1-1.10.9-0.91.0-0.5
Patch foraging water rate 18 sec0.10.10.90.50.0-0.2-0.10.10.2-0.20.20.1-0.9
Patch foraging water rate 24 sec0.91.32.71.6-1.21.21.1-1.1-1.10.8-0.80.7-1.3
Patch foraging water rate 6 sec0.20.31.2-0.00.0-0.1-0.10.10.2-0.80.6-0.9-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.5-0.2-0.2-0.10.10.2-0.20.1-0.5-0.1
Distance traveled before self-admin3.16.88.8-1.92.7-3.0-2.82.82.9-2.72.8-2.7-1.3
Distance traveled after self-admin2.34.05.6-0.81.5-2.4-2.22.22.3-1.92.2-2.3-1.5
Extensor digitorum longus weight0.41.82.51.6-1.41.61.4-1.4-1.41.1-1.20.8-1.0
Bone: elastic displacement0.10.10.4-0.0-0.20.30.4-0.4-0.40.4-0.50.60.0
Bone: elastic work0.50.63.60.10.4-0.5-0.50.50.5-0.60.7-0.6-1.9
Bone: endosteal estimation1.33.16.72.6-2.01.71.7-1.7-1.71.8-1.61.3-0.9
Bone: endosteal perimeter1.22.87.52.7-2.01.51.5-1.5-1.51.6-1.41.1-1.4
Epididymis fat weight4.020.241.76.5-4.84.14.3-4.3-4.34.5-4.24.1-3.3
Delta time in closed arm before/after self-admin1.11.01.3-0.11.0-1.2-1.11.11.1-1.11.1-0.8-0.8
Delta time in open arm before/after self-admin1.41.62.61.3-1.61.21.2-1.2-1.31.6-1.31.10.5
Diff in mean of infusions in LGA sessions0.20.41.3-1.00.9-0.2-0.10.10.2-0.20.00.61.2
Delay discount exponential model param1.31.82.6-1.31.6-1.6-1.41.41.5-1.31.5-1.2-0.1
Extinction: sum of active levers before priming1.32.02.40.8-1.61.41.4-1.4-1.41.5-1.51.41.4
Active lever presses in extinction session 60.30.30.80.9-0.90.40.4-0.4-0.50.6-0.50.3-0.1
Bone: final force0.61.02.61.6-1.11.11.0-1.0-1.00.8-0.70.6-1.0
Bone: final moment1.01.63.41.9-1.41.31.3-1.3-1.20.9-1.00.8-1.2
Food consumed during 24 hour testing period0.10.10.6-0.50.30.20.2-0.2-0.0-0.50.1-0.2-0.8
Glucose0.40.63.90.8-0.0-0.1-0.20.20.2-0.50.6-0.5-2.0
Heart weight0.91.43.21.8-0.61.01.0-1.0-1.00.9-1.01.5-1.4
Delay discount hyperbolic model param1.01.21.8-1.11.3-1.3-1.11.11.2-1.01.2-1.10.1
Intermittent access intake day 1-15 change0.21.43.31.8-1.11.01.0-1.0-1.01.2-1.11.1-1.0
Intermittent access intake escalation0.31.53.61.9-1.21.01.1-1.1-1.01.2-1.21.2-1.0
Intermittent access intake escalation 20.50.81.91.4-1.00.80.8-0.8-0.81.0-0.90.7-0.8
Intermitt. access day 1 inactive lever presses0.44.87.12.5-2.72.22.3-2.3-2.32.3-2.22.00.1
Intermitt. access day 15 inactive lever presses0.10.72.10.8-0.30.60.7-0.7-0.70.9-1.01.40.5
Intermitt. access escalation Index0.10.31.0-0.20.0-0.3-0.40.40.4-0.70.6-1.0-0.9
Intermittent access day 1 total infusions0.51.62.11.0-1.41.41.4-1.4-1.41.1-1.21.40.5
Intermittent access day 15 total infusions0.92.13.21.6-1.41.51.5-1.5-1.51.5-1.61.8-0.1
Intermittent access terminal intake (last 3 days)0.51.01.21.0-1.01.01.1-1.1-1.00.9-1.01.1-0.1
Intermittent access total infusions1.72.02.51.4-1.61.41.5-1.5-1.51.4-1.41.60.1
Intermittent access day 1 locomotion0.20.40.6-0.30.6-0.7-0.70.70.7-0.70.7-0.4-0.6
Intermittent access day 15 total locomotion0.20.62.11.5-1.00.30.3-0.3-0.40.8-0.60.6-1.0
Intermittent access total locomotion0.50.51.30.10.2-0.9-0.90.90.8-0.60.7-0.5-1.1
Intermittent access standard deviation0.52.53.11.7-1.71.71.7-1.7-1.61.5-1.51.80.1
Left kidney weight0.43.021.01.50.2-0.9-0.90.91.0-1.11.1-1.1-4.6
Right kidney weight0.43.125.02.3-0.1-0.2-0.10.10.2-0.50.5-0.4-5.0
Cocaine induced anxiety1.54.15.4-2.32.1-2.1-2.22.22.1-1.92.0-2.20.4
Post-drug Anxiety0.20.20.5-0.40.3-0.5-0.50.50.4-0.30.4-0.70.0
Baseline Anxiety3.15.16.32.4-2.42.52.5-2.5-2.42.3-2.32.10.1
Tail length0.10.40.70.5-0.50.50.5-0.5-0.50.8-0.80.8-0.8
Length with tail0.52.36.42.2-1.71.21.1-1.1-1.11.3-1.10.8-2.5
Length without tail1.47.217.54.2-3.32.32.4-2.4-2.32.4-2.11.5-2.9
Times rat made contact with spout0.70.82.30.9-1.01.00.9-0.9-0.80.2-0.40.1-1.5
Lifetime Intake1.92.43.01.6-1.71.61.7-1.7-1.61.5-1.61.70.2
Liver weight, left1.73.08.42.9-2.11.41.4-1.4-1.51.7-1.41.1-1.8
Liver weight, right1.52.614.72.7-1.40.60.5-0.5-0.50.4-0.2-0.1-3.8
Locomotor activity0.61.02.70.30.7-1.0-1.01.01.0-0.60.8-1.1-1.6
Locomotor testing distance1.22.94.2-0.31.5-1.8-1.81.81.8-1.51.7-1.8-2.1
Locomotor testing rearing0.31.11.90.10.8-1.2-1.21.21.1-0.81.0-1.1-1.4
Locomotion in novel chamber2.73.65.2-1.51.8-1.8-1.81.81.9-2.12.1-2.3-1.7
Locomotion in novel chamber post-restriction0.30.92.3-1.51.3-0.8-0.80.80.8-1.00.8-0.80.5
Fecal boli incidents, locomotor time 10.00.10.20.1-0.40.00.1-0.1-0.10.4-0.50.20.4
Change in fecal boli incidents, locomotor task0.10.20.6-0.10.7-0.4-0.40.40.40.2-0.20.50.3
Time >=10cm from walls, locomotor time 10.30.40.8-0.90.5-0.7-0.70.70.7-0.50.4-0.70.5
Bouts of movement, locomotor time 13.14.04.92.2-2.22.02.0-2.0-2.12.1-2.12.10.3
Total resting periods, locomotor time 13.03.54.42.1-2.11.91.9-1.9-1.92.0-1.92.10.3
Rest time, locomotor task time 10.10.10.40.7-0.1-0.1-0.10.10.00.2-0.10.4-0.4
Distance moved, locomotor task time 10.00.10.3-0.4-0.00.10.1-0.1-0.1-0.50.3-0.6-0.2
Vertical activity count, locomotor time 10.42.83.8-1.92.0-1.7-1.71.71.7-1.81.6-1.5-0.5
Time >=10cm from walls, locomotor time 20.10.31.31.1-0.80.30.3-0.3-0.40.8-0.60.5-0.1
Bouts of movement, locomotor time 20.00.10.6-0.80.40.00.0-0.00.0-0.00.0-0.20.6
Total resting periods, locomotor time 20.00.10.2-0.40.10.20.2-0.2-0.20.2-0.20.00.5
Rest time, locomotor task time 20.50.81.8-1.00.6-0.8-0.80.80.8-1.01.0-1.4-0.6
Distance moved, locomotor task time 21.01.31.71.0-0.91.31.3-1.3-1.31.3-1.21.20.6
Vertical activity count, locomotor time 20.00.10.20.5-0.30.20.3-0.3-0.30.4-0.40.3-0.1
Light reinforcement 10.10.51.9-0.90.6-0.7-0.60.60.6-0.10.1-0.21.4
Light reinforcement 20.40.92.1-1.51.0-0.9-0.90.90.9-0.70.7-0.71.2
Bone: marrow area1.33.16.82.6-2.01.71.7-1.7-1.71.8-1.61.4-1.0
Bone: maximum diameter3.46.814.13.8-3.22.42.4-2.4-2.52.8-2.42.0-1.5
Bone: maximum force0.40.81.71.3-1.01.01.0-1.0-0.90.6-0.70.7-0.9
Bone: maximum moment0.71.42.31.5-1.21.31.3-1.3-1.20.9-1.00.9-1.0
Mean time between licks in bursts0.31.72.60.9-0.91.51.4-1.4-1.41.3-1.51.60.6
Mean num. licks in bursts0.71.83.5-0.61.2-1.2-1.21.21.2-1.51.6-1.4-1.9
Cd content in liver4.44.97.3-1.72.7-2.4-2.42.42.4-2.42.4-1.8-0.9
Co content in liver2.63.04.3-1.41.8-2.1-2.02.02.0-1.71.7-1.5-0.2
Cu content in liver0.20.30.4-0.30.4-0.7-0.60.60.6-0.50.5-0.6-0.2
Fe content in liver1.41.82.31.3-1.51.41.3-1.3-1.41.5-1.41.4-0.1
K content in liver0.10.10.2-0.50.0-0.4-0.40.40.4-0.20.2-0.50.4
Mg content in liver0.00.00.2-0.2-0.3-0.1-0.10.1-0.00.2-0.1-0.00.5
Mn content in liver0.10.20.2-0.50.4-0.4-0.40.40.4-0.40.3-0.40.1
Na content in liver0.30.42.5-0.9-0.00.30.2-0.2-0.30.2-0.30.21.6
Rb content in liver0.50.62.2-0.2-0.40.60.6-0.6-0.60.8-0.90.91.5
Se content in liver0.40.41.8-1.30.3-0.4-0.40.40.4-0.30.3-0.51.1
Sr content in liver3.22.83.9-2.01.7-1.8-1.81.81.8-1.71.6-1.40.4
Zn content in liver1.11.31.6-1.11.0-1.2-1.31.31.2-1.21.2-1.1-0.1
Bone: minimum diameter1.93.77.62.8-2.11.81.8-1.8-1.92.0-1.81.6-1.2
Time in familiar zone, hab. session 12.52.83.8-1.41.8-2.0-2.02.01.9-1.51.6-1.5-0.2
Time in novel zone, hab. session 12.83.24.11.5-2.02.02.0-2.0-2.01.8-1.81.60.3
Total zone transitions, hab. session 10.30.42.90.6-0.40.40.4-0.4-0.3-0.1-0.1-0.0-1.7
Total locomotion distance, hab. session 10.30.51.0-0.0-0.71.00.9-0.9-0.90.3-0.60.4-0.2
Locomotion velocity, hab. session 10.30.40.9-0.1-0.60.90.9-0.9-0.90.3-0.60.4-0.2
Time in familiar zone, hab. session 23.94.46.42.5-2.11.92.0-2.0-2.12.5-2.42.30.1
Time in novel zone, hab. session 22.72.94.2-1.91.8-1.5-1.61.61.6-2.02.0-1.9-0.6
Total zone transitions, hab. session 20.50.63.21.0-0.40.50.6-0.6-0.50.3-0.40.5-1.8
Total locomotion distance, hab. session 20.40.61.80.8-0.60.70.8-0.8-0.70.4-0.50.5-1.3
Locomotion velocity, hab. session 20.20.31.20.5-0.40.50.5-0.5-0.50.1-0.30.3-1.1
Novel to familiar place preference ratio0.40.50.90.3-0.70.90.9-0.9-0.90.5-0.60.60.5
Novelty place preference0.40.50.90.5-0.80.90.9-0.9-0.90.6-0.60.60.5
Time in novel zone, NPP test1.21.42.11.0-1.21.41.4-1.4-1.41.2-1.11.00.4
Total zone transitions, NPP test1.11.62.81.7-1.31.21.3-1.3-1.20.9-1.11.0-1.4
Total locomotion distance, NPP test1.21.72.31.3-1.21.41.5-1.5-1.41.0-1.21.2-1.0
Locomotion velocity, NPP test0.30.51.20.7-0.60.70.8-0.8-0.70.2-0.50.6-1.1
Intraocular pressure3.15.17.52.7-1.92.42.4-2.4-2.42.1-2.22.5-0.8
Delta distance traveled before/after self-admin0.30.31.31.1-0.90.20.2-0.2-0.30.5-0.20.2-0.6
Delta ambulatory time before/after self-admin0.91.53.21.7-1.81.21.1-1.1-1.21.3-1.21.0-0.2
Parametrial fat weight7.317.133.65.8-4.64.14.0-4.0-4.14.2-3.93.8-2.1
Pavlov. Cond. lever latency0.40.50.70.9-0.80.80.8-0.8-0.80.7-0.50.5-0.4
Pavlov. Cond. magazine entry latency0.30.40.70.8-0.60.60.7-0.7-0.60.4-0.60.6-0.5
Pavlov. Cond. change in total contacts0.30.30.4-0.30.5-0.6-0.60.60.6-0.60.5-0.6-0.4
Pavlov. Cond. index score0.10.10.40.30.1-0.3-0.30.30.3-0.20.1-0.1-0.6
Pavlov. Cond. latency score0.10.10.30.10.2-0.4-0.40.40.4-0.30.2-0.2-0.5
Pavlov. Cond. lever contacts0.30.40.6-0.70.7-0.7-0.60.60.6-0.50.3-0.20.7
Pavlov. Cond. magazine entry number0.30.32.2-0.90.3-0.3-0.30.30.20.00.2-0.21.5
Pavlov. Cond. intertrial magazine entries0.10.10.20.3-0.00.20.2-0.2-0.20.3-0.30.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.30.0-0.2-0.20.20.2-0.2-0.0-0.0-0.4
Pavlov. Cond. response bias0.00.10.1-0.00.3-0.2-0.20.20.2-0.40.1-0.1-0.3
Pavlov. Cond. lever latency3.44.76.4-1.32.0-2.5-2.52.52.5-2.12.1-2.2-1.7
Pavlov. Cond. magazine entry latency2.02.83.81.9-1.92.01.9-1.9-1.91.6-1.51.3-0.5
Pavlov. Cond. change in total contacts2.46.08.31.5-2.22.92.8-2.8-2.82.4-2.52.61.1
Pavlov. Cond. index score3.55.47.81.9-2.32.82.7-2.7-2.72.2-2.22.20.7
Pavlov. Cond. latency score3.35.37.22.0-2.42.72.6-2.6-2.62.2-2.22.20.6
Pavlov. Cond. lever contacts2.23.34.71.0-1.72.22.1-2.1-2.11.7-1.71.81.1
Pavlov. Cond. magazine entry number2.63.45.0-1.82.0-2.2-2.22.22.1-1.61.7-1.50.3
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.10.3-0.7-0.60.60.6-0.10.2-0.30.1
Pavlov. Cond. lever-magazine prob. diff.3.04.66.91.7-2.22.62.6-2.6-2.51.9-2.02.00.5
Pavlov. Cond. response bias3.64.97.41.5-2.12.72.7-2.7-2.62.1-2.12.20.9
Time in closed arm before self-admin0.10.20.6-0.70.7-0.5-0.50.50.4-0.30.4-0.10.0
Time in closed arm after self-admin0.81.02.4-1.01.5-1.1-1.01.01.0-0.90.9-0.5-0.1
Time in open arm before self-admin0.20.20.7-0.70.1-0.1-0.20.20.2-0.40.3-0.70.8
Time in open arm after self-admin1.41.63.31.0-1.81.31.2-1.2-1.31.4-1.20.71.0
Bone: periosteal estimation2.35.512.43.5-2.72.22.2-2.2-2.22.3-2.11.7-1.9
Bone: periosteal perimeter2.95.713.23.6-2.92.22.2-2.2-2.22.3-2.01.5-2.0
Bone: post-yield work1.42.53.41.1-1.31.81.8-1.8-1.71.4-1.61.71.3
Progressive ratio test 1 active lever presses1.42.44.11.5-1.51.51.6-1.6-1.61.6-1.72.00.5
Progressive ratio test 1 breakpoint1.42.44.11.4-1.51.51.6-1.6-1.61.6-1.72.00.5
Progressive ratio test 1 inactive lever presses1.94.96.22.0-2.32.42.5-2.5-2.42.2-2.32.20.7
Progressive ratio test 2 active lever presses2.53.55.12.2-2.01.91.9-1.9-1.91.8-1.92.3-0.3
Progressive ratio test 2 breakpoint2.73.55.22.3-2.01.81.9-1.9-1.91.8-1.82.2-0.4
Progressive ratio test 2 inactive lever presses1.13.44.12.0-2.01.81.9-1.9-1.91.9-1.92.00.2
Incentive Sensitization - Responses0.92.64.02.0-1.71.71.7-1.7-1.71.4-1.51.6-0.4
Incentive Sensitization - Breakpoint1.02.33.61.9-1.71.61.6-1.6-1.61.4-1.41.5-0.4
Sum of active levers in priming session hrs 5-60.20.20.8-0.2-0.50.50.4-0.4-0.50.4-0.4-0.00.9
Progressive ratio0.10.31.1-0.80.00.40.5-0.5-0.50.0-0.20.11.1
Food seeking constrained by brief footshock2.32.93.90.7-1.21.92.0-2.0-1.91.6-1.81.81.6
Seeking ratio, punishment vs. effort0.20.41.31.1-0.60.50.5-0.5-0.40.7-0.70.8-0.3
Retroperitoneal fat weight6.428.663.58.0-5.95.05.0-5.0-5.15.3-4.84.6-3.6
Reaction time number correct0.62.23.51.9-1.71.51.6-1.6-1.51.4-1.41.1-0.6
Reaction time mean minus median0.00.10.40.6-0.50.00.1-0.1-0.10.3-0.20.1-0.2
Reaction time mean minus median AUC0.00.30.80.40.1-0.6-0.50.50.5-0.20.4-0.5-0.9
Reaction time num false alarms0.20.40.80.6-0.40.70.6-0.6-0.60.5-0.50.90.3
Reaction time num false alarms AUC0.00.10.30.4-0.10.40.3-0.3-0.30.2-0.20.60.1
Reaction time trials correct on left0.62.23.51.9-1.71.51.6-1.6-1.51.4-1.41.1-0.6
Reaction time trials on left0.72.33.61.9-1.71.51.6-1.6-1.61.4-1.51.2-0.7
Reaction time mean0.61.32.1-0.70.9-1.4-1.31.31.3-1.21.3-1.2-0.5
Reaction time mean AUC0.61.42.2-0.91.0-1.5-1.41.41.4-1.11.2-1.1-0.1
Median of all reaction times1.52.33.2-1.11.3-1.8-1.71.71.7-1.71.7-1.5-0.6
Reaction time omissions0.10.20.30.6-0.20.30.5-0.5-0.40.4-0.30.60.2
Reaction time false alarm rate0.10.10.4-0.50.6-0.2-0.30.30.2-0.30.30.20.6
Reaction time premature initiation rate0.91.43.1-0.30.6-1.1-1.11.11.1-1.21.2-1.6-1.8
Reaction time premature initiations0.30.85.20.8-0.3-0.2-0.20.20.3-0.50.5-1.0-2.3
Std. dev. reaction times0.00.20.70.8-0.4-0.1-0.00.00.00.2-0.00.0-0.8
Reaction time trials completed0.72.33.61.9-1.71.51.6-1.6-1.61.4-1.51.2-0.7
Reaction time trials AUC0.72.43.71.9-1.81.61.7-1.7-1.61.5-1.51.2-0.7
Run reversals in cocaine runway, females0.40.41.7-0.0-0.0-0.1-0.10.10.2-0.90.9-0.9-1.3
Run reversals in cocaine runway, males0.30.31.8-0.60.3-0.5-0.30.30.30.0-0.10.31.3
Latency to leave start box in cocaine runway0.40.61.1-1.00.8-0.7-0.80.80.7-0.50.6-0.80.5
Latency to leave start box in cocaine runway, F1.11.42.0-1.41.4-1.4-1.31.31.3-0.91.0-1.10.3
Latency to leave start box in cocaine runway, M0.30.31.00.5-0.41.00.5-0.5-0.70.5-0.40.50.2
Std. dev. time between licks in bursts1.63.03.90.9-1.51.91.9-1.9-1.91.9-2.01.81.5
Total sessions with >9 infusions1.11.32.61.6-1.11.11.2-1.2-1.11.0-1.01.3-0.8
Short access day 1 total inactive lever presses0.91.73.31.7-1.81.21.2-1.2-1.31.5-1.40.90.1
Short access day 10 total inactive lever presses0.10.41.11.0-0.70.60.6-0.6-0.60.4-0.40.3-0.6
Short access day 1 total infusions0.20.40.70.9-0.80.60.7-0.7-0.60.7-0.50.5-0.1
Short access day 10 total infusions0.50.81.30.3-0.81.11.1-1.1-1.00.7-0.91.10.7
Short access total infusions0.81.21.61.0-1.11.21.3-1.3-1.21.0-1.01.20.2
Short access day 1 locomotion0.60.91.51.0-1.21.00.9-0.9-1.01.0-1.01.00.5
Short access day 10 total locomotion0.52.23.0-0.30.9-1.6-1.71.71.6-1.41.6-1.6-1.7
Short access total locomotion0.20.41.20.20.4-0.6-0.60.60.6-0.60.6-0.3-1.1
One hour access (0.3 mA shock)7.79.213.02.7-3.63.13.2-3.2-3.23.2-3.22.91.4
Compulsive drug intake1.52.23.81.1-2.01.61.6-1.6-1.51.7-1.70.91.1
One hour access (shock baseline)0.20.51.00.9-0.70.60.6-0.6-0.60.8-0.71.0-0.1
Social response proportion0.91.25.90.70.3-0.6-0.70.70.7-1.01.1-1.1-2.4
Social responses2.63.48.02.8-2.11.61.7-1.7-1.71.8-1.81.6-1.1
Social time0.20.42.01.0-0.2-0.4-0.40.40.3-0.10.3-0.4-1.4
Soleus weight0.92.719.62.3-0.9-0.0-0.10.10.1-0.20.2-0.9-4.4
Bone: stiffness0.00.00.10.1-0.10.30.2-0.2-0.20.1-0.20.1-0.1
Tibialis anterior weight0.41.42.30.6-1.01.51.4-1.4-1.41.0-1.31.10.7
Time to tail flick, vehicle, before self-admin0.10.10.30.5-0.50.10.1-0.1-0.1-0.00.0-0.1-0.6
Time to tail flick, vehicle, after self-admin0.00.10.2-0.3-0.50.30.4-0.4-0.30.0-0.1-0.30.2
Time to tail flick, test, before self-admin1.31.52.1-0.51.1-1.3-1.41.41.3-1.31.4-1.2-1.1
Time to tail flick, test, after self-admin0.90.91.40.9-1.21.01.1-1.1-1.01.0-1.00.60.1
Delta time to tail flick, vehicle, before/after SA0.70.70.90.2-0.80.91.0-1.0-0.90.9-0.90.80.8
Delta time to tail flick, test, before/after SA0.60.71.00.5-0.90.91.0-1.0-1.00.8-1.00.60.3
Tibia length0.41.05.20.70.0-0.9-0.80.80.8-0.60.7-1.0-2.3
Ambulatory time before self-admin1.85.57.5-1.32.4-2.7-2.52.52.6-2.42.5-2.2-1.7
Ambulatory time after self-admin2.23.55.3-0.51.0-2.3-2.12.12.1-1.72.1-2.3-1.8
Bone: tissue strength0.10.10.4-0.20.30.10.1-0.1-0.10.2-0.40.60.6
Total heroin consumption2.53.04.82.2-1.51.81.8-1.8-1.81.7-1.72.1-0.3
Bone: trabecular number0.91.72.11.2-1.51.41.4-1.4-1.41.3-1.41.20.2
Bone: trabecular spacing0.00.10.4-0.30.20.0-0.00.0-0.00.00.10.10.6
Bone: trabecular thickness2.94.08.62.9-2.71.81.9-1.9-1.92.1-1.81.2-1.3
Bone: trabecular tissue density0.61.11.7-0.90.8-1.3-1.31.31.2-0.91.2-1.1-0.0
Water consumed over 24 hours0.20.42.4-0.20.1-0.3-0.30.30.4-0.70.5-0.9-1.6
Number of responses in last shaping day0.20.31.00.4-0.10.60.7-0.7-0.60.3-0.41.00.0