Hub : Genes

LOC102553576

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC102553576 0.33 0.16 7.5e-05 0.2 0.15 0.18 0.18 2.2e-05 2.5e-04 5.8e-05 3.7e-05
2 Liver alternative polyA XR_005496992.1 0.23 0.09 0.0e+00 0.26 0.01 0.25 0.05 3.8e-28 2.8e-02 5.4e-28 1.9e-06
3 NAcc mRNA stability LOC102553576 0.02 0.02 8.4e-03 0.01 0.01 0 0.01 1.5e-02 3.8e-02 1.1e-01 4.2e-02
4 BLA isoform ratio XR_005496992.1 0.07 0.05 2.8e-03 0.04 0.03 0.01 0.02 3.4e-03 6.0e-03 1.0e-01 2.9e-02
5 pVTA gene expression LOC102553576 0.26 0.25 2.6e-05 0.07 0.11 0.14 0.13 4.7e-04 2.3e-05 1.1e-06 2.9e-06
6 Liver mRNA stability LOC102553576 0.43 0.12 0.0e+00 0.5 0.1 0.51 0.2 3.0e-64 2.7e-11 3.9e-66 1.6e-21
7 BLA gene expression LOC102553576 0.09 0.05 1.9e-04 0.06 0.06 0.01 0.06 2.8e-04 5.1e-04 7.5e-02 3.7e-04
8 NAcc gene expression LOC102553576 0.13 0.07 1.3e-15 0.12 0.09 0.1 0.11 9.9e-14 5.3e-11 2.5e-11 8.4e-13
9 RMTg gene expression LOC102553576 0.18 0.1 1.5e-04 0.12 0.15 0.12 0.11 5.3e-04 8.2e-05 4.7e-04 7.7e-04
10 PL isoform ratio XR_005496992.1 0.03 0.02 7.1e-04 0.01 0.02 0.01 0.01 1.4e-02 4.1e-03 3.0e-02 5.5e-02
11 Brain isoform ratio XR_005496992.1 0.06 0.04 1.0e-07 0.06 0.07 0.07 0.06 1.3e-06 3.8e-07 4.8e-07 1.5e-06
12 Liver intron excision ratio chr19_18008033_18008164 0.17 0.08 0.0e+00 0.2 0.02 0.19 0.04 2.6e-21 3.1e-03 1.9e-20 5.1e-05
13 NAcc intron excision ratio chr19_18008033_18008164 0.05 0.03 3.1e-06 0.06 0.04 0.04 0.05 4.1e-07 4.7e-05 1.7e-05 3.5e-06
14 Brain gene expression LOC102553576 0.11 0.06 1.1e-13 0.14 0.14 0.14 0.14 9.6e-13 3.1e-13 8.4e-13 2.9e-13
15 IL gene expression LOC102553576 0.15 0.09 2.4e-03 0.14 0.09 0.11 0.12 2.5e-04 4.4e-03 1.1e-03 1.0e-03
16 Brain intron excision ratio chr19_18008033_18008164 0.06 0.04 5.9e-06 0.06 0.04 0.03 0.05 2.7e-06 6.0e-05 4.0e-04 1.0e-05
17 Liver alternative polyA XR_597179.3 0.25 0.09 0.0e+00 0.28 0.01 0.28 0.04 5.4e-31 2.2e-02 8.8e-32 3.3e-05
18 Liver isoform ratio XR_005496994.1 0.16 0.07 0.0e+00 0.22 0.04 0.21 0.09 1.3e-23 6.9e-05 4.0e-23 3.4e-10
19 Liver gene expression LOC102553576 0.65 0.18 0.0e+00 0.47 0.01 0.49 0.15 8.0e-59 6.0e-02 1.8e-61 1.4e-16
20 Liver alternative polyA XR_005496994.1 0.2 0.09 0.0e+00 0.18 0.01 0.19 0.01 6.8e-20 1.6e-02 2.3e-20 2.6e-02
21 Liver alternative polyA XR_005496992.1 0.2 0.09 0.0e+00 0.18 0.01 0.18 0.01 1.6e-19 1.3e-02 1.2e-19 1.3e-02
22 PL gene expression LOC102553576 0.19 0.11 1.7e-16 0.14 0.14 0.13 0.13 8.3e-15 4.3e-15 1.1e-13 2.4e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.11.82.9-1.7-1.7-1.51.7-1.3-1.4-1.0-1.61.7-1.6-1.6-1.2-1.21.4-1.0-1.01.1-1.0-1.21.0-1.01.0
Area under the delay curve0.60.61.51.10.60.5-0.61.20.81.00.7-0.90.80.91.11.0-0.60.80.6-0.50.90.8-0.50.5-0.6
BMI with tail1.75.67.52.72.42.7-2.52.12.32.62.5-2.42.52.42.22.2-2.32.22.5-2.22.22.1-2.32.3-2.1
BMI without tail0.10.31.11.00.00.2-0.00.90.40.70.4-0.50.30.40.60.6-0.30.70.5-0.40.80.4-0.50.5-0.2
Body weight0.62.55.42.31.61.7-1.60.91.61.31.7-1.31.41.21.41.5-1.61.71.8-1.71.71.6-1.81.8-0.8
Weight adjusted by age3.64.07.51.42.32.4-2.4-0.12.12.02.1-1.41.81.31.92.0-2.11.82.7-2.41.71.7-2.52.5-1.7
Bone surface0.20.41.2-0.7-1.0-1.11.0-0.1-0.7-0.2-0.80.6-0.7-0.6-0.5-0.50.6-0.2-0.40.6-0.3-0.50.5-0.50.3
Bone volume1.11.93.3-1.5-1.8-1.81.8-0.9-1.6-1.1-1.61.4-1.5-1.3-1.3-1.31.5-1.2-0.91.4-1.2-1.51.3-1.21.2
Breakpoint value in progressive ratio session0.60.71.4-0.7-0.8-0.80.8-1.1-0.7-1.2-0.71.1-1.0-1.1-0.8-0.80.8-0.6-1.00.6-0.7-0.60.7-0.70.9
Number of licking bursts0.40.51.2-0.6-0.7-0.80.7-0.5-0.6-0.6-0.70.8-0.8-0.8-0.8-0.80.8-0.5-1.10.6-0.6-0.40.6-0.60.9
Context. condit. distance diff. score3.44.26.41.62.12.3-2.21.72.41.92.3-1.82.01.72.22.2-2.22.10.7-2.22.12.5-1.81.8-2.2
Locomotion velocity, session 10.30.31.20.0-1.1-0.91.10.2-0.4-0.2-0.50.2-0.4-0.2-0.2-0.20.4-0.4-0.70.6-0.3-0.40.8-0.80.8
Locomotion distance, session 10.00.00.30.0-0.20.00.10.50.10.3-0.1-0.10.00.10.20.2-0.00.2-0.6-0.00.20.30.2-0.2-0.0
Locomotion velocity, session 20.10.10.20.1-0.4-0.20.30.40.10.40.1-0.10.10.10.20.2-0.10.2-0.4-0.10.30.30.2-0.2-0.2
Locomotion distance, session 20.20.20.60.50.40.5-0.30.20.60.80.3-0.10.20.10.60.6-0.50.6-0.1-0.70.70.7-0.50.5-0.3
Locomotion velocity, session 32.12.43.11.61.71.7-1.71.31.61.61.7-1.81.71.71.61.6-1.61.11.6-1.41.31.3-1.51.5-1.4
Locomotion distance, session 30.50.62.11.10.70.7-0.61.40.60.60.7-1.31.11.40.60.6-0.70.20.5-0.10.30.4-0.00.0-0.7
Stereotopy head waving bouts, day 31.21.42.91.21.01.0-1.11.71.11.01.2-1.41.31.41.31.3-1.21.10.9-1.01.21.1-0.90.9-1.3
Stereotopy head waving duration, day 31.82.13.01.31.21.3-1.41.71.41.31.4-1.41.41.41.71.6-1.51.61.0-1.41.61.6-1.41.4-1.4
Locomotion velocity, session 71.11.22.00.41.21.2-1.20.51.31.21.1-0.81.00.71.31.3-1.21.10.2-1.31.11.4-1.21.2-1.4
Locomotion distance, session 70.30.42.3-1.1-0.3-0.10.3-1.5-0.2-0.5-0.41.0-0.7-1.1-0.4-0.40.4-0.5-0.90.0-0.5-0.20.2-0.20.2
Stereotopy head waving bouts, day 71.51.77.51.51.00.9-1.12.70.91.01.1-2.01.72.11.21.1-1.11.01.0-0.51.00.9-0.50.5-1.2
Stereotopy head waving duration, day 70.40.54.90.8-0.1-0.3-0.02.2-0.20.2-0.1-1.20.71.30.20.2-0.10.00.30.60.1-0.10.5-0.5-0.0
Locomotion velocity, session 80.91.12.60.51.01.1-0.90.01.41.01.1-0.30.70.21.21.2-1.11.2-0.2-1.61.21.5-1.41.4-1.0
Locomotion distance, session 81.31.93.91.01.41.5-1.41.01.81.41.5-0.91.20.81.61.6-1.51.5-0.2-1.71.52.0-1.31.3-1.4
Degree of sensitization distance0.70.74.1-1.3-0.4-0.30.4-2.0-0.3-0.5-0.41.6-1.1-1.7-0.4-0.40.4-0.0-0.7-0.4-0.2-0.0-0.30.30.4
Degree of sensitization stereotypy1.51.77.11.51.00.8-1.12.70.91.11.0-2.01.62.11.21.2-1.11.01.2-0.51.10.8-0.50.5-1.0
Conditioned locomotion0.20.20.9-0.5-0.3-0.10.2-0.9-0.3-0.5-0.50.7-0.6-0.7-0.5-0.50.4-0.40.00.2-0.4-0.50.3-0.30.5
Cocaine response after cond. corrected1.01.22.20.91.11.5-1.10.21.41.11.3-0.70.90.61.11.1-1.11.00.6-1.41.11.2-1.11.1-1.1
Cocaine response after cond. not corrected0.80.91.71.11.01.2-1.00.31.30.91.1-0.60.80.51.01.0-1.00.80.7-1.21.01.0-1.01.0-0.8
Cocaine response before conditioning1.01.22.2-0.4-1.2-1.51.10.2-1.3-1.1-1.20.5-0.8-0.4-1.1-1.11.2-1.1-0.71.5-1.1-1.31.3-1.31.2
Saline control response1.52.05.9-1.8-1.4-1.41.5-2.0-0.8-0.9-1.42.3-2.0-2.4-0.9-0.91.2-0.5-2.20.3-0.6-0.40.5-0.51.4
Bone: connectivity density1.01.53.8-1.9-1.4-1.21.4-1.3-1.1-0.8-1.41.7-1.6-1.7-1.1-1.11.3-0.8-1.10.9-0.9-1.00.8-0.80.7
Bone: cortical apparent density0.20.32.00.10.30.7-0.21.40.30.50.3-0.80.60.90.50.5-0.40.40.1-0.00.50.40.00.0-0.9
Bone: cortical area0.10.10.4-0.1-0.6-0.40.60.1-0.4-0.1-0.30.1-0.2-0.0-0.2-0.20.2-0.3-0.30.4-0.2-0.30.3-0.30.2
Bone: cortical porosity0.00.00.20.10.40.2-0.50.20.40.1-0.1-0.00.00.00.00.0-0.0-0.0-0.1-0.1-0.00.1-0.10.10.3
Bone: cortical porosity0.10.10.40.30.2-0.0-0.30.60.1-0.0-0.3-0.20.00.3-0.1-0.10.2-0.2-0.20.3-0.2-0.20.2-0.20.4
Bone: cortical thickness0.00.00.20.1-0.10.10.20.4-0.20.1-0.1-0.20.10.30.00.00.0-0.00.30.20.0-0.20.1-0.1-0.0
Bone: cortical thickness0.30.40.90.30.50.3-0.50.00.80.80.30.00.2-0.10.80.8-0.60.90.0-1.00.80.8-0.90.9-0.5
Bone: cortical tissue density0.20.32.00.10.30.7-0.21.40.30.50.3-0.80.60.90.50.5-0.40.40.1-0.10.50.4-0.00.0-0.9
Condit. Reinf. active minus inactive responses1.51.710.21.40.71.1-0.83.20.91.10.8-2.01.62.21.21.2-1.00.60.5-0.20.90.7-0.10.1-1.4
Condit. Reinf. active-inactive response ratio1.51.64.91.51.01.2-1.02.21.31.21.2-1.61.51.71.31.3-1.20.80.4-0.91.11.2-0.70.7-1.3
Condit. Reinf. active responses0.50.66.10.7-0.30.00.22.5-0.20.2-0.3-1.20.71.40.30.3-0.0-0.20.00.70.1-0.20.7-0.7-0.5
Condit. Reinf. inactive responses2.63.15.0-1.6-2.1-2.02.1-0.6-2.2-1.7-2.11.2-1.5-1.0-1.7-1.71.9-1.7-1.12.2-1.7-2.12.1-2.11.5
Incentive salience index mean0.60.85.70.2-0.6-0.40.62.4-0.6-0.2-0.6-0.90.41.2-0.2-0.20.4-0.8-0.81.3-0.5-0.61.3-1.3-0.2
Condit. Reinf. lever presses1.72.34.9-1.1-1.6-1.81.60.9-1.7-1.3-1.40.3-0.7-0.0-1.4-1.41.5-1.9-1.62.2-1.6-1.72.2-2.20.9
Condit. Reinf. active minus inactive responses0.00.10.20.4-0.10.3-0.10.4-0.00.00.2-0.40.30.50.10.1-0.20.00.40.10.10.0-0.0-0.0-0.2
Condit. Reinf. active-inactive response ratio0.10.10.90.7-0.10.20.0-0.1-0.00.20.0-0.20.10.20.10.1-0.10.11.0-0.10.2-0.1-0.20.20.2
Condit. Reinf. active responses0.10.10.70.5-0.10.1-0.10.80.10.20.2-0.50.40.50.40.4-0.30.40.3-0.10.50.4-0.20.2-0.3
Condit. Reinf. inactive responses0.50.61.20.50.60.5-0.80.90.80.60.8-0.60.70.50.80.8-0.81.00.0-0.90.91.1-0.80.8-0.7
Condit. Reinf. lever presses0.60.81.30.80.70.7-0.91.00.70.71.0-0.90.90.90.90.9-0.91.10.8-0.91.01.1-1.01.0-0.9
Condit. Reinf. lever reinforcers received0.30.41.20.80.30.4-0.51.10.40.40.6-0.80.70.80.60.6-0.60.80.7-0.40.80.7-0.50.5-0.5
Conditioned reinforcement - actives0.90.91.60.81.01.0-1.0-0.11.01.01.1-0.40.60.31.11.0-1.01.20.9-1.21.11.1-1.31.3-0.6
Conditioned reinforcement - inactives1.61.82.91.51.01.1-1.01.41.41.61.3-1.31.31.21.51.4-1.41.70.7-1.31.71.6-1.01.0-1.0
Conditioned locomotion0.10.10.20.00.20.2-0.2-0.00.30.30.3-0.10.20.00.40.4-0.30.40.1-0.40.40.4-0.40.4-0.4
Patch foraging indifference point 0 sec1.01.63.11.61.11.0-1.11.41.61.31.2-1.11.11.01.41.4-1.31.5-0.0-1.51.61.8-1.11.1-1.1
Patch foraging indifference point AUC2.12.43.8-1.4-1.4-1.31.3-1.6-1.5-2.0-1.61.6-1.6-1.5-1.7-1.71.6-1.8-1.41.5-1.7-1.61.5-1.51.5
Delay disc. indifference point, 0s delay1.11.22.2-0.6-1.4-1.31.4-0.8-1.0-1.0-1.21.2-1.3-1.2-0.9-0.91.2-0.9-1.01.0-0.9-1.01.0-1.01.5
Delay disc. indifference point, 16s delay0.90.91.30.91.00.9-1.00.60.91.01.0-0.90.90.81.11.0-0.91.11.1-0.91.00.9-0.90.9-0.8
Delay disc. indifference point, 2s delay1.01.11.91.30.80.7-0.81.01.01.20.9-0.90.90.91.41.4-1.01.11.3-1.01.21.0-1.21.1-0.9
Delay disc. indifference point, 24s delay0.10.10.80.30.10.0-0.10.90.10.30.1-0.60.40.60.40.3-0.00.20.10.20.30.20.3-0.3-0.2
Delay disc. indifference point, 4s delay0.10.10.30.10.10.2-0.10.30.40.50.2-0.10.10.10.60.5-0.20.4-0.2-0.30.50.4-0.20.2-0.3
Delay disc. indifference point, 8s delay1.51.53.31.81.11.0-1.11.81.31.31.1-1.41.31.41.51.5-1.11.20.8-0.91.31.2-0.70.7-1.0
Indifference point function ln k2.43.36.01.51.51.6-1.42.31.82.41.7-2.01.92.02.02.0-1.92.01.2-1.62.01.9-1.51.5-1.9
Indifference point function log k2.43.36.01.51.51.6-1.42.31.82.41.7-2.01.92.02.02.0-1.92.01.2-1.62.01.9-1.51.5-1.9
Patch foraging total patch changes 0 sec1.32.13.91.81.21.2-1.31.41.81.61.4-1.21.31.11.61.6-1.51.70.1-1.71.82.0-1.41.4-1.2
Patch foraging total patch changes 12 sec0.60.83.0-0.7-1.1-0.71.0-0.3-0.7-1.1-1.00.9-0.9-0.9-0.7-0.80.8-0.8-1.70.7-0.7-0.51.0-1.00.8
Patch foraging total patch changes 18 sec2.02.54.2-1.4-1.7-1.51.7-1.6-1.3-1.7-1.81.8-1.8-1.8-1.6-1.61.5-1.5-2.01.3-1.4-1.31.5-1.51.5
Patch foraging total patch changes 24 sec0.50.72.8-0.6-0.9-0.80.9-0.7-0.5-1.2-0.70.8-0.8-0.9-0.6-0.60.7-0.7-1.70.5-0.6-0.30.9-0.90.8
Patch foraging total patch changes 6 sec0.10.21.0-0.0-0.3-0.40.1-0.4-0.1-0.6-0.40.5-0.5-0.5-0.4-0.40.4-0.4-1.00.2-0.3-0.20.4-0.40.5
Patch foraging time to switch 0 sec0.00.10.3-0.00.0-0.1-0.0-0.1-0.2-0.1-0.1-0.20.10.3-0.2-0.20.1-0.2-0.20.4-0.2-0.20.5-0.50.2
Patch foraging water rate 0 sec0.10.21.00.0-0.5-0.30.5-0.5-0.20.1-0.40.9-0.7-1.0-0.2-0.10.30.1-0.0-0.20.0-0.0-0.30.30.6
Patch foraging water rate 12 sec0.30.40.8-0.7-0.8-0.80.8-0.1-0.9-0.4-0.60.7-0.7-0.7-0.8-0.80.8-0.4-0.30.7-0.6-0.60.4-0.40.4
Patch foraging water rate 18 sec1.62.23.9-0.9-1.9-1.81.8-0.3-2.0-1.7-1.41.1-1.4-1.1-1.6-1.61.7-1.3-0.51.8-1.4-1.81.3-1.31.5
Patch foraging water rate 24 sec0.00.10.5-0.1-0.4-0.10.40.7-0.50.1-0.2-0.0-0.10.1-0.2-0.20.20.10.10.3-0.1-0.10.1-0.1-0.1
Patch foraging water rate 6 sec2.84.16.3-2.3-2.4-2.32.5-1.7-2.1-1.8-2.02.3-2.2-2.3-2.0-1.92.0-1.9-1.91.7-1.9-1.81.5-1.51.7
Seeking ratio, delayed vs. immediate footshock4.95.76.72.22.42.3-2.42.62.62.22.4-2.42.52.42.52.5-2.52.41.7-2.32.42.5-2.22.2-2.5
Distance traveled before self-admin1.01.11.81.31.01.0-1.01.30.90.71.0-1.41.31.40.90.9-1.00.81.3-0.80.80.7-0.80.8-1.0
Distance traveled after self-admin0.10.20.8-0.1-0.3-0.30.3-0.4-0.5-0.9-0.30.2-0.3-0.2-0.4-0.40.3-0.20.50.4-0.2-0.50.2-0.20.6
Extensor digitorum longus weight0.10.51.4-0.6-0.5-0.20.5-1.2-0.7-0.6-0.60.6-0.6-0.6-0.7-0.70.6-0.71.00.6-0.7-1.10.4-0.40.8
Bone: elastic displacement0.10.10.8-0.40.40.4-0.4-0.90.1-0.2-0.10.4-0.2-0.4-0.2-0.20.1-0.20.2-0.1-0.3-0.2-0.10.10.1
Bone: elastic work0.00.00.3-0.10.20.2-0.1-0.50.10.0-0.10.3-0.2-0.3-0.1-0.10.10.00.2-0.1-0.0-0.1-0.20.20.3
Bone: endosteal estimation0.00.10.30.00.20.1-0.3-0.30.30.30.5-0.10.30.00.40.4-0.40.2-0.0-0.50.20.4-0.50.5-0.3
Bone: endosteal perimeter0.20.41.10.50.40.3-0.50.20.70.70.9-0.50.60.40.70.7-0.80.6-0.3-0.90.61.0-0.70.7-0.8
Epididymis fat weight0.10.20.70.50.40.4-0.3-0.10.60.40.5-0.00.1-0.10.40.5-0.40.9-0.1-0.70.80.8-0.50.5-0.1
Delta time in closed arm before/after self-admin1.81.72.91.41.21.1-1.21.61.21.71.2-1.41.41.41.41.4-1.31.21.2-1.21.31.2-1.21.2-1.4
Delta time in open arm before/after self-admin3.13.05.6-1.9-1.6-1.51.6-2.4-1.5-1.8-1.62.0-1.9-2.0-1.9-1.81.7-1.6-1.91.3-1.6-1.41.5-1.51.7
Diff in mean of infusions in LGA sessions0.10.10.7-0.20.00.1-0.0-0.90.0-0.20.10.4-0.2-0.4-0.2-0.20.0-0.1-0.5-0.2-0.10.1-0.10.1-0.0
Delay discount exponential model param0.70.71.8-1.0-0.6-0.50.6-1.3-0.8-1.0-0.71.0-0.9-1.0-1.1-1.10.7-0.8-0.50.5-0.9-0.80.4-0.40.8
Extinction: sum of active levers before priming3.03.03.81.51.91.9-1.91.11.81.51.9-1.71.81.71.81.8-1.81.51.8-1.71.51.6-1.71.7-1.9
Active lever presses in extinction session 60.10.10.2-0.3-0.2-0.20.20.2-0.3-0.3-0.2-0.30.10.4-0.1-0.10.1-0.3-0.20.4-0.2-0.30.4-0.4-0.2
Bone: final force1.01.63.1-0.6-1.6-1.51.6-0.8-1.4-1.0-1.61.2-1.4-1.2-1.1-1.11.3-1.0-0.71.3-1.0-1.41.1-1.11.8
Bone: final moment0.50.82.0-0.3-1.3-1.21.2-0.4-1.1-0.7-1.20.8-1.0-0.8-0.7-0.70.9-0.6-0.50.9-0.7-1.00.8-0.81.4
Food consumed during 24 hour testing period6.17.49.4-2.7-3.0-3.13.0-2.3-2.7-2.6-2.92.8-2.9-2.8-2.6-2.62.7-2.7-3.02.5-2.6-2.52.6-2.62.7
Glucose0.20.31.2-0.1-0.2-0.60.2-1.1-0.3-0.2-0.50.9-0.7-1.0-0.2-0.20.30.1-0.4-0.2-0.1-0.1-0.40.30.8
Heart weight2.63.64.61.91.91.7-1.82.11.91.92.1-2.12.12.11.81.8-2.01.91.7-1.71.92.0-1.71.7-2.0
Delay discount hyperbolic model param0.70.82.1-1.1-0.6-0.60.6-1.4-0.8-1.0-0.71.0-0.9-1.0-1.2-1.10.7-0.9-0.50.5-1.0-0.80.5-0.50.8
Intermittent access intake day 1-15 change3.83.74.5-1.9-2.1-2.12.1-1.5-1.9-1.8-1.91.9-2.0-1.9-2.0-1.92.0-1.9-2.11.8-1.8-1.82.0-2.02.0
Intermittent access intake escalation5.65.56.7-2.2-2.6-2.62.6-1.7-2.4-2.3-2.42.2-2.3-2.2-2.5-2.42.4-2.3-2.52.3-2.2-2.22.5-2.52.4
Intermittent access intake escalation 23.23.25.8-1.7-2.0-1.92.0-0.8-1.8-1.7-1.71.4-1.6-1.4-1.8-1.81.8-1.8-2.41.9-1.7-1.62.1-2.11.6
Intermitt. access day 1 inactive lever presses0.40.42.20.40.40.4-0.41.50.40.70.5-1.10.91.20.70.7-0.60.10.5-0.20.30.2-0.20.2-0.9
Intermitt. access day 15 inactive lever presses0.70.81.70.60.80.8-0.81.30.90.90.7-1.11.11.20.80.8-0.90.70.3-0.70.80.8-0.50.5-1.3
Intermitt. access escalation Index0.20.20.8-0.3-0.6-0.60.60.1-0.4-0.3-0.50.3-0.4-0.2-0.3-0.20.5-0.4-0.90.6-0.3-0.30.7-0.70.4
Intermittent access day 1 total infusions2.93.44.71.92.22.1-2.20.81.81.72.0-1.71.81.61.91.8-1.91.82.1-1.91.71.8-1.91.9-1.6
Intermittent access day 15 total infusions0.00.00.6-0.10.0-0.0-0.0-0.8-0.1-0.10.00.3-0.2-0.4-0.2-0.20.1-0.00.0-0.1-0.1-0.0-0.00.00.2
Intermittent access terminal intake (last 3 days)0.10.10.20.30.30.4-0.3-0.30.30.30.5-0.20.20.10.30.2-0.30.50.2-0.40.50.5-0.30.3-0.2
Intermittent access total infusions0.10.20.40.40.50.5-0.5-0.60.30.30.5-0.10.20.00.30.2-0.40.60.5-0.50.40.5-0.40.4-0.1
Intermittent access day 1 locomotion0.60.72.00.90.90.9-0.90.30.60.70.9-0.80.90.80.80.8-0.80.71.4-0.70.60.5-0.80.8-0.7
Intermittent access day 15 total locomotion0.20.21.40.30.50.5-0.5-0.50.20.50.5-0.20.30.10.30.3-0.40.71.2-0.50.50.3-0.60.6-0.1
Intermittent access total locomotion0.30.31.50.70.60.6-0.6-0.40.40.50.6-0.30.30.20.40.4-0.50.81.2-0.60.60.4-0.70.60.0
Intermittent access standard deviation0.30.30.5-0.2-0.6-0.50.60.5-0.6-0.6-0.40.1-0.2-0.0-0.6-0.60.5-0.6-0.60.7-0.6-0.50.7-0.70.2
Left kidney weight0.20.51.0-0.4-0.6-0.40.7-0.8-0.7-0.8-0.70.6-0.6-0.6-0.9-0.90.7-0.8-0.10.7-0.9-0.90.6-0.71.0
Right kidney weight0.10.21.21.10.40.5-0.40.70.50.00.4-0.70.60.70.30.3-0.40.30.5-0.20.30.3-0.10.10.1
Cocaine induced anxiety1.41.73.51.31.11.1-1.11.11.71.21.2-0.71.00.61.41.4-1.31.5-0.1-1.71.51.9-1.41.4-1.3
Post-drug Anxiety0.90.91.81.00.80.8-0.81.31.21.00.8-0.80.90.81.11.0-0.91.00.1-1.01.11.2-0.90.9-1.2
Baseline Anxiety0.60.71.4-0.8-0.6-0.60.6-1.0-1.0-0.8-0.70.7-0.8-0.6-0.9-1.00.8-0.90.21.0-0.9-1.20.7-0.71.0
Tail length1.64.96.9-1.8-2.6-2.62.6-1.6-2.4-2.4-2.32.1-2.3-2.1-2.1-2.12.3-2.0-2.12.2-1.9-2.12.2-2.22.4
Length with tail0.10.41.2-0.1-0.5-0.70.5-1.1-0.5-1.1-0.40.8-0.7-0.8-0.6-0.60.4-0.3-0.50.3-0.4-0.30.4-0.41.0
Length without tail1.32.94.61.92.11.9-2.10.51.91.31.8-1.41.61.21.51.5-1.91.81.7-2.01.71.8-2.01.9-1.2
Times rat made contact with spout0.00.00.2-0.0-0.4-0.40.40.1-0.2-0.1-0.30.2-0.2-0.2-0.0-0.00.20.00.20.10.0-0.20.2-0.20.3
Lifetime Intake0.10.10.50.30.50.4-0.5-0.70.30.20.40.00.1-0.10.20.1-0.30.50.3-0.50.40.5-0.40.4-0.1
Liver weight, left0.20.30.80.50.50.2-0.6-0.70.70.70.10.6-0.3-0.70.20.2-0.20.9-0.4-0.80.70.8-0.70.60.3
Liver weight, right0.00.10.20.20.20.2-0.2-0.40.3-0.1-0.10.4-0.3-0.50.10.00.00.2-0.2-0.30.10.2-0.30.30.3
Locomotor activity0.40.61.60.81.10.6-1.1-0.00.80.40.6-0.20.40.10.60.6-0.60.90.9-1.00.70.7-1.31.3-0.3
Locomotor testing distance0.30.61.50.31.00.7-1.0-0.50.80.60.60.00.3-0.20.60.6-0.60.90.6-1.10.70.8-1.21.2-0.5
Locomotor testing rearing0.50.72.8-0.9-0.7-0.90.7-0.7-0.6-0.8-0.81.2-1.0-1.2-0.8-0.80.9-0.6-1.70.4-0.7-0.40.6-0.60.9
Locomotion in novel chamber0.50.61.51.20.70.8-0.70.90.81.20.6-0.80.70.80.80.7-0.70.91.1-0.50.80.6-0.50.5-0.2
Locomotion in novel chamber post-restriction0.20.20.6-0.3-0.2-0.30.2-0.0-0.6-0.5-0.30.0-0.10.0-0.5-0.60.5-0.80.10.7-0.7-0.70.4-0.40.2
Fecal boli incidents, locomotor time 11.41.53.0-1.4-0.9-1.00.9-1.4-1.0-1.3-1.11.4-1.3-1.4-1.4-1.41.2-1.0-1.71.0-1.1-0.91.3-1.31.2
Change in fecal boli incidents, locomotor task0.10.10.50.3-0.1-0.00.10.70.00.1-0.1-0.20.10.30.30.2-0.10.1-0.20.00.10.20.1-0.0-0.3
Time >=10cm from walls, locomotor time 10.20.20.40.0-0.3-0.40.3-0.1-0.5-0.6-0.40.1-0.2-0.1-0.5-0.50.4-0.6-0.10.6-0.6-0.50.4-0.40.5
Bouts of movement, locomotor time 10.91.03.2-1.8-1.0-0.91.0-0.9-1.1-0.7-1.00.9-0.9-0.9-0.7-0.81.0-1.0-0.90.9-0.9-0.90.9-0.90.5
Total resting periods, locomotor time 10.50.52.8-1.7-0.7-0.50.7-0.8-0.8-0.5-0.70.6-0.6-0.5-0.4-0.50.7-0.8-0.60.7-0.7-0.70.7-0.70.1
Rest time, locomotor task time 10.60.72.4-1.6-0.8-0.60.8-0.7-0.9-0.8-0.80.7-0.7-0.7-0.7-0.70.8-1.1-0.90.8-1.0-0.80.8-0.80.2
Distance moved, locomotor task time 10.70.81.11.01.10.8-1.10.50.90.80.9-0.70.80.70.80.9-0.91.00.9-0.90.90.9-1.00.9-0.7
Vertical activity count, locomotor time 10.40.41.30.0-0.6-0.80.6-0.6-0.4-0.5-0.70.8-0.8-0.8-0.5-0.50.7-0.2-0.40.5-0.3-0.50.5-0.51.2
Time >=10cm from walls, locomotor time 20.20.31.01.00.30.4-0.30.30.50.50.4-0.40.40.40.40.5-0.60.50.9-0.60.50.4-0.60.6-0.1
Bouts of movement, locomotor time 20.20.20.5-0.20.30.5-0.30.10.20.50.4-0.40.40.40.50.5-0.40.10.6-0.40.30.2-0.50.5-0.7
Total resting periods, locomotor time 20.00.00.3-0.50.10.2-0.1-0.10.00.30.1-0.10.10.10.20.2-0.2-0.10.1-0.20.00.0-0.30.3-0.5
Rest time, locomotor task time 20.30.32.0-1.4-0.3-0.30.3-0.9-0.3-0.4-0.40.8-0.6-0.8-0.3-0.30.4-0.6-1.10.1-0.6-0.20.1-0.1-0.3
Distance moved, locomotor task time 21.51.74.52.11.31.2-1.31.31.31.21.2-1.41.31.41.21.3-1.31.31.7-1.11.31.1-1.21.2-0.7
Vertical activity count, locomotor time 20.10.21.20.7-0.4-0.40.40.3-0.0-0.1-0.40.2-0.4-0.3-0.10.10.30.2-0.20.20.2-0.10.4-0.41.1
Light reinforcement 115.528.132.5-5.0-5.7-5.45.6-4.5-5.5-5.6-5.45.3-5.5-5.2-5.5-5.55.4-5.3-5.15.1-5.3-5.25.0-5.05.3
Light reinforcement 211.415.318.0-4.2-4.2-4.24.2-3.5-4.0-4.1-4.04.1-4.1-4.1-4.0-4.04.0-3.6-3.83.6-3.8-3.63.6-3.63.7
Bone: marrow area0.10.20.40.20.20.2-0.3-0.30.40.40.6-0.20.30.10.50.5-0.50.40.1-0.60.30.5-0.60.6-0.4
Bone: maximum diameter0.40.71.21.10.60.5-0.61.00.70.81.0-1.11.01.10.90.9-1.00.70.3-0.70.70.9-0.70.7-0.9
Bone: maximum force0.10.20.6-0.0-0.7-0.70.8-0.3-0.5-0.1-0.70.6-0.6-0.6-0.3-0.30.4-0.1-0.30.3-0.1-0.30.2-0.20.7
Bone: maximum moment0.00.10.20.2-0.5-0.40.50.0-0.30.1-0.40.3-0.3-0.3-0.0-0.00.20.2-0.20.10.1-0.1-0.0-0.00.5
Mean time between licks in bursts0.50.74.40.80.70.6-0.62.10.30.50.7-1.51.21.60.30.3-0.50.1-0.00.40.20.40.3-0.3-0.8
Mean num. licks in bursts0.30.31.20.40.30.5-0.30.60.40.40.4-0.70.60.80.70.7-0.60.41.1-0.30.40.2-0.30.4-0.7
Cd content in liver0.20.21.00.30.20.4-0.21.00.30.50.3-0.70.50.70.50.5-0.40.5-0.5-0.30.40.6-0.10.1-0.6
Co content in liver0.30.43.50.50.30.5-0.51.90.10.20.0-1.10.71.20.10.1-0.10.20.70.30.30.10.1-0.1-0.4
Cu content in liver0.10.20.90.90.10.4-0.00.90.10.30.1-0.60.40.60.20.2-0.20.50.30.20.50.20.2-0.2-0.2
Fe content in liver0.60.81.9-0.5-0.9-0.70.9-0.6-1.1-1.1-1.00.5-0.7-0.4-0.9-0.90.9-0.90.71.1-0.9-1.40.8-0.80.9
K content in liver0.20.20.60.70.30.4-0.40.80.20.20.1-0.50.40.50.10.1-0.20.40.8-0.10.40.2-0.30.3-0.1
Mg content in liver1.11.22.81.70.71.1-0.91.61.01.10.7-1.11.01.11.01.0-0.91.31.2-0.81.31.0-0.90.9-0.7
Mn content in liver0.80.92.20.91.01.5-1.00.21.10.80.9-0.50.70.50.90.9-0.91.21.2-1.11.11.0-1.11.1-0.8
Na content in liver0.10.10.50.5-0.1-0.20.0-0.5-0.2-0.2-0.00.2-0.1-0.2-0.2-0.20.10.10.70.00.0-0.1-0.10.10.4
Rb content in liver0.50.61.50.2-1.2-0.81.00.8-0.8-0.7-1.20.5-0.8-0.4-0.7-0.70.9-0.3-0.20.9-0.2-0.70.7-0.71.2
Se content in liver1.72.03.4-1.0-1.8-1.71.8-0.6-1.6-1.3-1.71.0-1.2-0.8-1.3-1.31.5-1.5-0.51.7-1.4-1.91.7-1.71.6
Sr content in liver0.10.10.20.4-0.2-0.20.20.4-0.3-0.3-0.2-0.20.00.2-0.3-0.30.2-0.3-0.10.5-0.3-0.30.4-0.40.3
Zn content in liver2.93.24.11.71.72.0-1.71.42.01.91.8-1.51.71.51.91.9-1.92.01.3-1.91.92.0-1.71.7-1.9
Bone: minimum diameter1.01.92.6-1.3-1.6-1.31.6-1.3-1.6-1.3-1.31.3-1.3-1.3-1.4-1.41.3-1.4-0.91.4-1.4-1.51.3-1.31.3
Time in familiar zone, hab. session 11.11.12.1-0.9-1.0-0.91.00.1-1.2-0.9-0.80.2-0.5-0.1-1.1-1.10.9-1.5-0.91.5-1.3-1.31.5-1.50.7
Time in novel zone, hab. session 10.70.71.90.60.90.9-0.9-0.40.80.70.7-0.20.40.10.80.8-0.71.11.4-1.11.00.7-1.21.2-0.7
Total zone transitions, hab. session 10.20.30.50.60.60.4-0.60.30.70.60.6-0.30.40.30.50.5-0.50.40.1-0.60.50.7-0.50.5-0.5
Total locomotion distance, hab. session 10.40.61.20.40.90.9-0.9-0.21.00.90.9-0.30.50.20.80.9-0.80.70.5-1.10.70.8-1.01.0-0.8
Locomotion velocity, hab. session 10.40.61.30.40.90.9-0.9-0.11.10.90.8-0.30.50.20.90.9-0.80.70.4-1.10.70.9-1.01.0-0.7
Time in familiar zone, hab. session 21.61.73.1-1.4-1.2-1.21.3-1.0-1.2-1.3-1.11.0-1.1-1.0-1.4-1.41.2-1.7-1.81.3-1.6-1.31.4-1.40.8
Time in novel zone, hab. session 23.33.35.71.71.82.0-1.81.11.91.81.7-1.41.51.41.91.9-1.82.22.4-1.92.11.7-1.91.9-1.4
Total zone transitions, hab. session 20.10.10.70.4-0.1-0.20.10.80.30.40.0-0.10.10.20.40.4-0.20.4-0.5-0.20.40.5-0.10.1-0.2
Total locomotion distance, hab. session 20.10.10.40.30.10.3-0.1-0.30.50.50.30.2-0.0-0.20.50.5-0.30.40.0-0.70.50.5-0.50.5-0.2
Locomotion velocity, hab. session 20.10.10.30.1-0.2-0.00.2-0.50.20.2-0.00.5-0.3-0.50.20.2-0.00.2-0.1-0.40.30.2-0.30.30.2
Novel to familiar place preference ratio1.61.62.71.01.31.2-1.21.21.21.51.1-1.11.11.01.41.4-1.21.61.3-1.31.51.4-1.41.4-1.2
Novelty place preference1.21.22.10.81.11.0-1.10.71.11.31.0-0.70.90.71.21.2-1.01.41.1-1.21.31.2-1.31.4-1.0
Time in novel zone, NPP test1.21.21.90.91.10.9-1.11.01.11.31.0-0.91.00.91.21.2-1.01.41.3-1.11.31.1-1.31.3-1.0
Total zone transitions, NPP test0.10.10.60.5-0.10.20.10.80.20.30.0-0.20.10.20.20.2-0.10.3-0.2-0.00.30.30.2-0.20.1
Total locomotion distance, NPP test0.20.20.50.60.20.5-0.20.70.50.70.4-0.50.40.50.60.6-0.40.50.6-0.40.60.4-0.20.3-0.3
Locomotion velocity, NPP test0.00.00.10.3-0.20.30.20.20.20.40.1-0.00.00.00.30.3-0.10.20.1-0.20.30.2-0.00.00.0
Intraocular pressure5.17.19.42.12.82.8-2.82.42.82.32.9-2.72.82.62.72.7-2.82.72.2-2.62.72.8-2.52.5-3.1
Delta distance traveled before/after self-admin1.31.42.3-1.2-1.2-1.11.2-1.5-1.2-1.3-1.21.3-1.3-1.3-1.1-1.11.2-0.9-0.81.0-1.0-1.11.1-1.11.4
Delta ambulatory time before/after self-admin2.02.23.1-1.4-1.6-1.41.6-1.3-1.5-1.6-1.61.5-1.6-1.4-1.4-1.41.6-1.3-1.31.5-1.3-1.51.7-1.71.8
Parametrial fat weight0.00.10.30.50.20.1-0.2-0.50.2-0.20.10.1-0.1-0.1-0.1-0.1-0.0-0.1-0.3-0.1-0.10.00.1-0.10.5
Pavlov. Cond. lever latency0.10.11.0-0.40.1-0.0-0.2-1.00.1-0.20.00.5-0.3-0.6-0.2-0.20.0-0.1-0.4-0.3-0.20.1-0.30.30.1
Pavlov. Cond. magazine entry latency0.10.10.60.00.30.4-0.40.40.20.20.2-0.50.40.60.20.2-0.20.00.80.00.0-0.10.0-0.0-0.3
Pavlov. Cond. change in total contacts0.50.51.2-0.2-1.0-1.11.10.6-0.8-0.5-0.80.1-0.40.0-0.4-0.40.7-0.6-0.21.0-0.5-0.91.1-1.10.6
Pavlov. Cond. index score0.20.31.30.50.40.4-0.41.20.30.40.3-0.80.60.90.40.4-0.30.40.7-0.00.40.2-0.00.0-0.5
Pavlov. Cond. latency score0.10.20.80.20.30.3-0.30.90.30.40.3-0.60.50.70.40.4-0.30.30.4-0.00.30.20.0-0.0-0.5
Pavlov. Cond. lever contacts0.20.21.40.70.0-0.00.11.20.10.40.2-0.60.40.70.50.5-0.20.50.50.00.60.2-0.0-0.0-0.2
Pavlov. Cond. magazine entry number0.20.21.2-0.4-0.2-0.10.2-1.1-0.1-0.1-0.10.8-0.5-0.9-0.3-0.30.2-0.1-0.8-0.2-0.10.2-0.20.20.2
Pavlov. Cond. intertrial magazine entries0.20.20.70.80.20.6-0.30.90.30.40.2-0.40.30.40.40.4-0.30.60.3-0.30.60.5-0.30.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.50.60.50.5-0.51.20.50.50.5-0.90.71.00.60.6-0.50.60.8-0.30.60.4-0.30.3-0.6
Pavlov. Cond. response bias0.40.52.80.90.10.2-0.21.70.20.50.3-1.10.81.20.60.6-0.40.51.20.10.60.1-0.00.0-0.4
Pavlov. Cond. lever latency0.30.30.80.10.50.8-0.4-0.80.70.90.30.2-0.0-0.30.60.6-0.50.40.6-0.90.50.4-0.90.9-0.3
Pavlov. Cond. magazine entry latency0.10.10.40.2-0.2-0.30.10.6-0.2-0.10.0-0.20.10.2-0.2-0.20.10.0-0.40.3-0.10.10.4-0.40.1
Pavlov. Cond. change in total contacts0.20.22.10.4-0.4-0.40.11.4-0.4-0.4-0.2-0.60.30.7-0.1-0.10.20.1-0.00.6-0.0-0.10.6-0.60.2
Pavlov. Cond. index score0.10.11.10.4-0.2-0.4-0.01.0-0.3-0.4-0.0-0.50.30.5-0.2-0.20.10.1-0.00.5-0.00.00.4-0.40.1
Pavlov. Cond. latency score0.10.10.70.3-0.2-0.40.10.8-0.3-0.4-0.1-0.40.20.4-0.3-0.30.2-0.0-0.00.5-0.1-0.10.5-0.50.2
Pavlov. Cond. lever contacts0.60.81.5-0.4-0.9-1.20.70.3-1.1-1.2-0.80.3-0.5-0.2-0.9-0.90.9-0.8-0.91.2-0.9-0.81.2-1.20.8
Pavlov. Cond. magazine entry number0.10.10.7-0.5-0.10.00.2-0.8-0.1-0.1-0.30.5-0.4-0.5-0.1-0.10.2-0.4-0.2-0.0-0.3-0.3-0.10.10.1
Pavlov. Cond. intertrial magazine entries0.50.71.4-0.8-0.8-0.70.9-1.1-0.7-0.8-1.01.2-1.1-1.2-0.7-0.70.8-0.6-0.80.5-0.6-0.70.6-0.60.9
Pavlov. Cond. lever-magazine prob. diff.0.10.21.40.5-0.2-0.40.01.2-0.3-0.3-0.0-0.60.30.6-0.1-0.10.10.1-0.10.5-0.00.00.5-0.50.1
Pavlov. Cond. response bias0.20.20.80.2-0.4-0.70.20.9-0.5-0.6-0.2-0.30.00.3-0.4-0.40.3-0.1-0.40.7-0.3-0.20.7-0.70.4
Time in closed arm before self-admin3.23.65.7-1.7-1.9-2.12.0-0.5-2.1-1.6-2.01.2-1.5-1.0-2.1-2.12.0-2.3-1.62.4-2.2-2.22.3-2.31.7
Time in closed arm after self-admin0.40.40.7-0.5-0.7-0.80.80.4-0.80.0-0.80.3-0.5-0.2-0.6-0.60.7-0.6-0.30.8-0.5-0.70.7-0.70.6
Time in open arm before self-admin2.93.14.02.01.81.8-1.81.21.91.41.8-1.61.71.52.02.0-1.91.81.7-1.91.91.8-1.91.9-1.5
Time in open arm after self-admin0.50.50.90.90.80.8-0.8-0.20.90.40.8-0.50.60.40.70.8-0.80.80.6-1.00.80.8-0.80.8-0.5
Bone: periosteal estimation0.00.00.1-0.2-0.3-0.20.3-0.3-0.2-0.10.10.1-0.1-0.1-0.0-0.0-0.0-0.2-0.3-0.0-0.1-0.0-0.00.00.0
Bone: periosteal perimeter0.30.41.00.50.40.3-0.50.60.70.80.8-0.60.70.60.80.8-0.80.6-0.2-0.80.71.0-0.60.7-0.8
Bone: post-yield work0.40.51.50.70.1-0.30.10.70.60.90.6-0.30.40.20.80.8-0.71.1-0.4-0.91.11.2-0.70.7-0.7
Progressive ratio test 1 active lever presses1.31.42.61.41.31.2-1.3-0.11.21.11.2-0.70.90.61.11.1-1.21.51.6-1.41.31.2-1.41.4-0.5
Progressive ratio test 1 breakpoint0.90.92.01.21.11.0-1.1-0.20.90.91.0-0.50.70.40.90.8-0.91.21.4-1.21.11.0-1.11.1-0.3
Progressive ratio test 1 inactive lever presses0.20.20.60.70.40.3-0.40.70.20.30.3-0.70.60.80.10.2-0.30.30.6-0.10.30.10.0-0.0-0.2
Progressive ratio test 2 active lever presses0.20.20.70.50.70.7-0.7-0.00.30.50.5-0.60.60.60.40.4-0.50.50.8-0.40.40.3-0.40.4-0.3
Progressive ratio test 2 breakpoint0.30.40.80.50.80.8-0.8-0.20.50.60.6-0.50.60.40.50.5-0.60.70.9-0.60.60.5-0.60.6-0.3
Progressive ratio test 2 inactive lever presses2.42.83.31.71.71.7-1.71.51.61.81.8-1.81.81.81.71.7-1.71.71.6-1.61.71.6-1.41.4-1.7
Incentive Sensitization - Responses0.00.00.3-0.40.00.0-0.0-0.5-0.1-0.1-0.20.2-0.2-0.2-0.1-0.10.1-0.0-0.20.1-0.1-0.10.1-0.10.2
Incentive Sensitization - Breakpoint0.10.10.3-0.5-0.1-0.10.1-0.6-0.2-0.1-0.30.3-0.3-0.3-0.2-0.20.2-0.1-0.30.1-0.1-0.20.2-0.20.2
Sum of active levers in priming session hrs 5-60.10.10.4-0.1-0.2-0.20.2-0.5-0.1-0.6-0.20.3-0.3-0.4-0.1-0.10.10.1-0.60.0-0.00.00.1-0.10.1
Progressive ratio0.30.31.7-0.9-0.4-0.30.5-1.3-0.1-0.5-0.21.0-0.7-1.0-0.1-0.10.2-0.2-0.5-0.3-0.10.0-0.20.20.2
Food seeking constrained by brief footshock2.02.53.8-1.5-1.9-2.01.8-0.9-1.6-1.5-1.71.6-1.7-1.6-1.6-1.61.6-1.6-2.01.4-1.5-1.41.4-1.41.3
Seeking ratio, punishment vs. effort0.70.91.7-0.2-1.0-1.10.90.4-1.1-0.7-1.10.3-0.6-0.2-1.1-1.11.0-1.0-0.71.3-1.0-1.21.2-1.21.0
Retroperitoneal fat weight0.31.02.31.01.11.3-1.1-0.51.41.11.1-0.30.60.20.90.9-1.11.20.3-1.51.11.3-1.11.1-0.5
Reaction time number correct1.11.62.51.41.21.3-1.31.61.31.51.0-1.41.31.41.31.3-1.21.21.2-1.01.31.1-1.01.0-1.2
Reaction time mean minus median1.01.33.01.41.01.0-1.10.60.91.11.0-1.11.11.11.21.2-1.21.11.7-1.11.10.8-1.41.4-0.7
Reaction time mean minus median AUC0.91.12.81.11.11.2-1.20.21.01.01.1-1.11.11.01.01.0-1.10.91.7-1.11.00.7-1.11.1-0.7
Reaction time num false alarms5.06.89.63.12.62.7-2.52.92.92.92.7-2.72.72.62.72.7-2.52.61.9-2.42.62.6-2.12.2-2.4
Reaction time num false alarms AUC4.76.48.93.02.62.4-2.53.02.82.82.6-2.72.62.62.62.6-2.42.51.8-2.32.52.6-2.12.1-2.4
Reaction time trials correct on left1.11.62.51.41.21.3-1.31.61.31.51.0-1.41.31.41.31.3-1.21.21.2-1.01.31.1-1.01.0-1.2
Reaction time trials on left1.21.82.51.51.31.4-1.41.61.41.51.1-1.41.41.51.31.3-1.31.31.3-1.11.41.1-1.11.1-1.3
Reaction time mean1.72.45.51.61.61.8-1.51.01.41.51.6-1.71.71.61.51.5-1.71.42.3-1.41.41.2-1.61.6-1.2
Reaction time mean AUC1.92.55.41.61.71.8-1.60.91.51.61.7-1.71.71.71.61.6-1.71.42.3-1.41.41.3-1.61.6-1.3
Median of all reaction times1.52.14.61.31.51.8-1.41.11.31.41.5-1.71.71.61.41.4-1.61.32.1-1.21.21.1-1.31.3-1.2
Reaction time omissions1.52.03.31.61.81.7-1.8-0.11.51.21.7-1.11.30.91.21.2-1.51.11.6-1.71.01.3-1.81.8-0.9
Reaction time false alarm rate1.52.12.81.71.51.4-1.41.61.71.51.6-1.51.51.51.41.4-1.41.30.8-1.31.41.5-1.11.1-1.4
Reaction time premature initiation rate4.56.09.2-2.5-2.5-2.52.5-1.7-2.5-2.8-2.32.2-2.3-2.1-2.5-2.52.3-2.7-3.02.5-2.7-2.22.5-2.52.0
Reaction time premature initiations1.52.14.0-1.4-1.5-1.41.4-0.8-1.5-1.7-1.41.2-1.3-1.2-1.5-1.51.4-1.7-2.01.5-1.6-1.31.6-1.61.1
Std. dev. reaction times1.01.42.51.51.21.2-1.20.41.21.21.2-1.01.11.01.21.2-1.31.11.6-1.31.21.1-1.51.4-0.7
Reaction time trials completed1.21.82.51.51.31.4-1.41.61.41.51.1-1.41.41.51.31.3-1.31.31.3-1.11.41.1-1.11.1-1.3
Reaction time trials AUC1.31.82.61.61.31.5-1.31.61.41.61.1-1.41.41.51.41.4-1.31.31.3-1.21.41.1-1.11.1-1.3
Run reversals in cocaine runway, females1.41.32.21.41.00.9-1.20.71.31.51.1-0.80.90.71.31.3-1.11.31.1-1.41.31.1-1.41.4-0.7
Run reversals in cocaine runway, males0.20.20.60.20.50.5-0.50.10.30.10.1-0.10.10.10.50.5-0.20.60.7-0.50.50.3-0.50.5-0.3
Latency to leave start box in cocaine runway0.20.30.80.20.20.3-0.3-0.50.60.90.30.2-0.0-0.40.40.4-0.40.70.1-0.80.60.8-0.80.8-0.2
Latency to leave start box in cocaine runway, F0.70.71.70.60.80.9-0.8-0.50.91.20.7-0.20.50.10.70.7-0.80.91.1-1.10.90.8-1.31.3-0.6
Latency to leave start box in cocaine runway, M1.61.55.8-0.9-1.7-1.51.6-0.7-0.7-0.8-1.21.5-1.5-1.6-1.0-1.01.1-0.7-2.40.8-0.7-0.31.1-1.11.3
Std. dev. time between licks in bursts0.60.71.6-0.8-0.6-0.30.6-0.2-0.9-0.8-0.80.3-0.5-0.3-1.0-1.00.9-1.1-0.51.3-1.1-1.11.2-1.20.6
Total sessions with >9 infusions0.60.60.90.80.90.8-0.90.50.60.90.9-1.00.91.00.70.7-0.80.80.9-0.60.80.7-0.60.6-0.7
Short access day 1 total inactive lever presses0.40.52.2-0.5-0.6-0.50.6-1.5-0.4-0.4-0.60.9-0.8-1.0-0.6-0.60.5-0.4-0.60.3-0.4-0.40.5-0.51.0
Short access day 10 total inactive lever presses0.50.61.1-0.9-0.8-0.70.8-0.0-0.8-0.7-0.70.4-0.5-0.3-0.7-0.70.8-1.0-0.91.0-0.9-0.81.0-1.00.5
Short access day 1 total infusions1.71.82.31.51.41.4-1.40.81.31.41.5-1.31.41.31.31.4-1.41.51.3-1.41.41.4-1.21.2-1.1
Short access day 10 total infusions0.10.21.10.10.50.4-0.5-1.10.2-0.10.30.3-0.1-0.4-0.1-0.2-0.20.40.4-0.60.20.4-0.60.6-0.0
Short access total infusions0.10.10.70.30.30.2-0.3-0.80.20.10.20.2-0.1-0.30.00.0-0.10.40.2-0.40.30.3-0.30.30.2
Short access day 1 locomotion1.81.93.11.31.51.5-1.51.11.21.51.5-1.71.71.81.11.2-1.51.41.5-1.21.41.2-1.11.1-1.5
Short access day 10 total locomotion0.30.30.60.60.60.5-0.60.70.40.60.6-0.80.70.80.50.6-0.50.50.7-0.40.50.5-0.30.3-0.6
Short access total locomotion0.91.01.50.91.01.0-1.00.60.91.01.0-1.01.11.01.01.0-1.00.91.2-1.00.90.9-0.90.9-1.1
One hour access (0.3 mA shock)0.10.10.5-0.40.20.1-0.2-0.70.20.20.20.2-0.0-0.20.0-0.1-0.10.4-0.4-0.30.30.5-0.10.1-0.3
Compulsive drug intake0.70.81.5-1.2-1.0-1.01.0-0.6-0.8-0.8-1.00.9-0.9-0.9-0.7-0.70.9-0.8-1.20.8-0.8-0.70.8-0.80.5
One hour access (shock baseline)0.70.81.30.71.11.1-1.1-0.10.91.01.1-0.70.80.60.70.7-1.01.10.8-1.11.11.1-1.00.9-0.9
Social response proportion0.10.10.6-0.10.00.4-0.1-0.8-0.2-0.2-0.00.2-0.1-0.2-0.3-0.30.2-0.60.50.2-0.5-0.60.1-0.10.4
Social responses0.10.10.20.10.30.4-0.40.20.30.00.4-0.30.30.30.20.2-0.3-0.1-0.3-0.2-0.10.2-0.10.1-0.3
Social time1.72.23.9-1.9-1.1-0.91.1-1.7-1.6-1.8-1.31.1-1.2-1.1-1.7-1.71.4-2.0-0.61.6-1.9-2.01.5-1.51.1
Soleus weight0.00.10.4-0.40.50.1-0.4-0.60.1-0.30.4-0.00.20.0-0.2-0.2-0.1-0.3-0.5-0.1-0.40.10.1-0.1-0.4
Bone: stiffness0.10.10.50.2-0.6-0.70.6-0.3-0.30.0-0.40.4-0.4-0.40.00.00.20.1-0.00.00.1-0.1-0.10.10.7
Tibialis anterior weight0.62.13.71.31.51.7-1.41.41.31.41.3-1.61.61.61.51.5-1.51.31.9-1.21.31.1-1.31.3-1.4
Time to tail flick, vehicle, before self-admin0.20.20.7-0.9-0.1-0.20.1-0.6-0.10.2-0.00.8-0.5-0.9-0.2-0.20.2-0.1-0.8-0.2-0.10.2-0.40.5-0.4
Time to tail flick, vehicle, after self-admin0.90.92.4-1.0-0.9-1.00.9-1.0-0.7-0.8-0.91.3-1.1-1.3-1.1-1.10.9-0.8-1.60.7-0.9-0.50.6-0.60.7
Time to tail flick, test, before self-admin0.80.81.80.60.70.7-0.7-0.51.11.10.70.20.2-0.41.01.0-0.81.30.2-1.31.21.3-1.11.1-0.3
Time to tail flick, test, after self-admin0.30.30.7-0.8-0.6-0.70.6-0.6-0.6-0.6-0.60.6-0.6-0.7-0.4-0.40.5-0.5-0.50.4-0.5-0.50.3-0.30.5
Delta time to tail flick, vehicle, before/after SA0.50.51.1-0.4-0.7-0.70.7-0.4-0.5-0.8-0.70.5-0.6-0.5-0.8-0.80.7-0.8-1.00.6-0.7-0.50.9-0.90.8
Delta time to tail flick, test, before/after SA0.60.61.5-0.5-0.7-0.80.70.0-1.1-1.1-0.70.1-0.30.0-0.8-0.80.7-1.10.31.0-1.0-1.20.7-0.70.5
Tibia length0.20.53.21.80.4-0.1-0.40.70.40.70.5-0.70.60.70.60.6-0.60.81.0-0.50.80.6-0.80.80.0
Ambulatory time before self-admin1.31.32.11.31.21.1-1.21.01.10.91.2-1.31.31.21.01.0-1.21.01.4-1.11.01.0-1.21.2-1.0
Ambulatory time after self-admin0.80.92.0-0.8-1.0-0.91.0-0.9-1.0-1.4-1.00.9-1.0-0.9-0.9-0.91.0-0.8-0.30.9-0.8-1.00.8-0.81.2
Bone: tissue strength0.40.40.9-0.5-0.5-0.20.5-0.0-0.8-0.7-0.70.2-0.4-0.2-0.7-0.70.7-0.7-0.10.9-0.7-0.80.8-0.80.6
Total heroin consumption0.10.10.40.60.10.0-0.10.20.3-0.30.2-0.10.10.00.20.2-0.20.4-0.3-0.30.30.5-0.10.10.1
Bone: trabecular number1.01.63.0-1.7-1.5-1.31.4-1.1-1.4-1.0-1.61.4-1.4-1.4-1.1-1.11.4-1.1-0.81.2-1.1-1.41.0-1.00.7
Bone: trabecular spacing0.60.81.80.91.01.3-1.00.80.90.71.0-1.01.01.00.80.8-0.90.60.8-0.70.70.8-0.70.7-0.5
Bone: trabecular thickness2.22.63.9-1.7-1.9-1.72.0-1.7-1.7-1.4-1.91.9-1.9-1.9-1.5-1.51.7-1.3-0.71.4-1.4-1.71.3-1.21.6
Bone: trabecular tissue density0.50.81.61.00.50.6-0.30.40.91.10.6-0.30.50.21.11.1-0.91.30.7-1.21.21.0-1.21.2-0.3
Water consumed over 24 hours3.34.04.6-2.1-2.1-2.12.1-1.8-2.0-2.0-2.02.0-2.0-2.0-2.0-2.02.0-1.9-1.62.0-2.0-2.12.0-2.01.9
Number of responses in last shaping day5.25.46.62.32.22.3-2.22.22.32.62.3-2.52.52.52.52.6-2.42.42.0-2.12.52.3-2.02.0-2.4