Hub : Genes

LOC102551736

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	alternative polyA	XR_005491773.2	0.06	0.04	9.0e-03	0.01	0.02	0.04	0.02	9.1e-02	4.7e-02	5.5e-03	1.9e-02
2	Brain	alternative polyA	XR_005491773.2	0.03	0.02	7.8e-03	0.01	0.02	0.01	0.01	4.9e-02	5.8e-03	1.7e-02	4.4e-02
3	Brain	alternative polyA	XR_005491774.2	0.03	0.02	8.8e-03	0.01	0.02	0.01	0.01	5.4e-02	7.2e-03	2.2e-02	4.8e-02
4	Adipose	gene expression	LOC102551736	0.05	0.04	1.6e-03	0.01	0.01	0.01	0.01	8.9e-03	1.5e-02	1.4e-02	1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	2.6	4.4	9.8	-3.1	-1.4	1.4	1.9
Area under the delay curve	0.8	0.9	2.1	1.5	0.4	-0.4	-1.1
BMI with tail	1.5	5.1	7.7	-1.8	-2.2	2.2	2.8
BMI without tail	0.5	1.5	2.6	-1.6	1.0	-1.0	-1.1
Body weight	2.8	12.2	45.0	-6.7	-1.2	1.3	1.0
Weight adjusted by age	0.6	0.9	1.6	-1.3	0.9	-0.9	-0.7
Bone surface	1.3	2.4	7.1	-2.7	-1.0	1.0	0.8
Bone volume	2.3	4.0	5.5	-2.4	-2.0	2.0	1.6
Breakpoint value in progressive ratio session	0.4	0.5	1.2	-0.2	0.7	-0.6	-1.1
Number of licking bursts	0.6	1.0	1.9	-1.4	1.0	-1.0	0.0
Context. condit. distance diff. score	1.1	1.3	1.8	-1.2	-1.3	1.3	-0.5
Locomotion velocity, session 1	0.7	0.7	1.2	-0.3	1.1	-1.1	-0.7
Locomotion distance, session 1	1.2	1.5	3.0	0.1	1.7	-1.7	0.2
Locomotion velocity, session 2	1.5	1.8	3.0	-1.1	1.7	-1.7	0.0
Locomotion distance, session 2	3.1	4.3	7.6	-1.1	2.7	-2.7	-1.0
Locomotion velocity, session 3	0.4	0.5	0.9	0.2	-0.9	0.9	0.5
Locomotion distance, session 3	0.3	0.3	0.5	0.3	0.5	-0.5	-0.7
Stereotopy head waving bouts, day 3	1.5	1.8	3.3	-1.8	1.1	-1.1	-1.2
Stereotopy head waving duration, day 3	0.2	0.2	0.9	-0.1	-0.1	0.1	-1.0
Locomotion velocity, session 7	0.9	0.9	2.4	0.8	-0.6	0.6	-1.5
Locomotion distance, session 7	1.0	1.2	3.9	0.9	-0.3	0.3	-2.0
Stereotopy head waving bouts, day 7	2.3	2.6	3.3	0.8	1.8	-1.8	-1.7
Stereotopy head waving duration, day 7	0.9	1.1	1.4	0.7	1.2	-1.2	-0.9
Locomotion velocity, session 8	0.9	1.1	1.6	-0.4	1.3	-1.3	-1.0
Locomotion distance, session 8	1.0	1.5	4.0	-2.0	0.7	-0.7	-1.0
Degree of sensitization distance	0.3	0.3	1.1	0.4	-0.0	0.0	-1.1
Degree of sensitization stereotypy	0.7	0.7	1.2	1.1	0.9	-0.9	-0.5
Conditioned locomotion	0.2	0.2	0.3	0.5	0.4	-0.4	-0.5
Cocaine response after cond. corrected	0.8	1.0	1.5	1.1	-0.8	0.8	1.2
Cocaine response after cond. not corrected	1.1	1.3	1.8	1.2	-1.0	1.0	1.3
Cocaine response before conditioning	0.1	0.1	0.2	0.3	-0.4	0.5	-0.3
Saline control response	3.1	4.1	5.3	-1.2	2.2	-2.2	-2.3
Bone: connectivity density	1.7	2.7	10.5	-3.2	-0.4	0.4	-0.0
Bone: cortical apparent density	0.5	0.7	1.5	0.2	-0.8	0.8	1.2
Bone: cortical area	0.6	0.8	1.7	-1.3	-0.8	0.8	0.5
Bone: cortical porosity	0.8	0.8	1.5	0.2	1.2	-1.2	-0.4
Bone: cortical porosity	0.7	0.7	1.1	0.4	1.0	-1.1	-0.8
Bone: cortical thickness	0.5	0.8	1.1	-1.1	-0.8	0.8	0.9
Bone: cortical thickness	0.6	0.7	1.2	1.0	0.6	-0.6	-1.1
Bone: cortical tissue density	0.5	0.7	1.5	0.3	-0.8	0.8	1.2
Condit. Reinf. active minus inactive responses	0.8	0.9	1.0	-0.8	-1.0	1.0	0.9
Condit. Reinf. active-inactive response ratio	1.6	1.7	2.8	-0.1	-1.7	1.7	1.1
Condit. Reinf. active responses	0.3	0.4	1.0	-0.6	-0.2	0.2	1.0
Condit. Reinf. inactive responses	0.3	0.4	0.8	0.3	0.9	-0.9	0.1
Incentive salience index mean	0.2	0.2	0.4	-0.1	-0.5	0.5	0.7
Condit. Reinf. lever presses	0.2	0.3	0.9	1.0	-0.1	0.1	0.4
Condit. Reinf. active minus inactive responses	0.9	1.2	2.2	0.2	1.1	-1.1	-1.5
Condit. Reinf. active-inactive response ratio	1.4	1.6	2.4	0.5	1.4	-1.4	-1.5
Condit. Reinf. active responses	0.7	1.0	1.7	-0.3	1.0	-1.0	-1.3
Condit. Reinf. inactive responses	0.1	0.1	0.5	-0.7	0.2	-0.2	-0.1
Condit. Reinf. lever presses	0.1	0.1	0.1	0.2	-0.3	0.4	-0.3
Condit. Reinf. lever reinforcers received	0.6	0.9	1.4	-0.3	1.0	-1.0	-1.2
Conditioned reinforcement - actives	0.9	1.5	4.4	-2.1	0.9	-0.9	-0.2
Conditioned reinforcement - inactives	0.3	0.4	0.9	-0.9	0.2	-0.2	0.7
Conditioned locomotion	0.1	0.2	0.3	-0.5	0.4	-0.4	0.1
Patch foraging indifference point 0 sec	0.6	1.0	1.3	-1.0	-1.1	1.2	0.8
Patch foraging indifference point AUC	0.0	0.0	0.1	-0.3	0.1	-0.1	0.2
Delay disc. indifference point, 0s delay	0.1	0.1	0.3	0.1	-0.2	0.2	-0.5
Delay disc. indifference point, 16s delay	0.3	0.3	0.8	0.9	-0.4	0.4	-0.2
Delay disc. indifference point, 2s delay	1.1	1.2	3.1	1.8	0.4	-0.4	-1.2
Delay disc. indifference point, 24s delay	0.3	0.3	1.0	1.0	-0.0	0.0	-0.6
Delay disc. indifference point, 4s delay	0.6	0.6	2.3	1.5	-0.0	0.0	-0.2
Delay disc. indifference point, 8s delay	0.4	0.5	1.5	1.2	0.3	-0.3	-0.6
Indifference point function ln k	0.2	0.4	1.5	-1.2	0.3	-0.3	0.2
Indifference point function log k	0.2	0.4	1.5	-1.2	0.3	-0.3	0.2
Patch foraging total patch changes 0 sec	0.5	0.9	1.3	-0.9	-1.1	1.1	0.5
Patch foraging total patch changes 12 sec	1.2	1.6	2.4	-0.7	-1.5	1.5	1.0
Patch foraging total patch changes 18 sec	0.5	0.7	1.2	0.0	-1.1	1.1	0.8
Patch foraging total patch changes 24 sec	0.1	0.1	0.3	-0.0	-0.5	0.5	0.0
Patch foraging total patch changes 6 sec	0.1	0.1	0.3	0.1	-0.5	0.5	-0.2
Patch foraging time to switch 0 sec	0.7	1.3	4.1	2.0	-0.8	0.8	-0.1
Patch foraging water rate 0 sec	0.6	1.3	5.4	-2.3	0.0	-0.0	-0.1
Patch foraging water rate 12 sec	0.5	1.2	3.5	-1.9	0.6	-0.5	-0.7
Patch foraging water rate 18 sec	0.7	1.0	2.1	0.1	1.0	-1.0	-1.4
Patch foraging water rate 24 sec	1.8	2.5	3.4	-1.9	1.7	-1.7	-0.9
Patch foraging water rate 6 sec	0.7	1.0	2.3	-1.5	-0.9	0.9	-0.3
Seeking ratio, delayed vs. immediate footshock	0.3	0.3	1.2	1.1	0.1	-0.1	0.3
Distance traveled before self-admin	1.0	1.3	1.6	0.9	-1.2	1.2	1.3
Distance traveled after self-admin	0.1	0.1	0.2	0.5	-0.0	-0.0	-0.4
Extensor digitorum longus weight	0.7	2.6	7.6	-2.8	-1.1	1.2	-0.1
Bone: elastic displacement	0.9	1.1	2.0	-0.5	1.4	-1.4	0.2
Bone: elastic work	1.1	1.4	3.3	-1.8	1.1	-1.1	0.3
Bone: endosteal estimation	0.6	1.4	2.6	-1.6	1.0	-1.0	-0.9
Bone: endosteal perimeter	0.4	0.8	3.3	-1.8	0.0	-0.0	-0.3
Epididymis fat weight	1.4	4.7	7.5	-1.1	-2.7	2.7	1.6
Delta time in closed arm before/after self-admin	0.1	0.1	0.3	-0.5	-0.2	0.2	-0.2
Delta time in open arm before/after self-admin	1.3	1.3	4.6	2.1	0.4	-0.5	-0.4
Diff in mean of infusions in LGA sessions	0.5	0.6	1.4	1.2	-0.7	0.7	-0.2
Delay discount exponential model param	1.0	1.1	3.0	-1.7	-0.4	0.4	1.0
Extinction: sum of active levers before priming	0.7	0.8	1.7	-0.2	-0.8	0.8	1.3
Active lever presses in extinction session 6	0.7	0.7	1.0	-0.9	-1.0	1.0	0.2
Bone: final force	0.2	0.4	0.5	-0.7	0.7	-0.7	-0.4
Bone: final moment	0.2	0.3	0.4	-0.6	0.6	-0.6	-0.1
Food consumed during 24 hour testing period	0.8	1.1	1.6	1.0	1.3	-1.3	0.0
Glucose	0.4	0.6	1.1	0.0	-0.8	0.8	1.1
Heart weight	0.7	1.0	2.6	-1.6	0.8	-0.8	0.5
Delay discount hyperbolic model param	1.0	1.1	3.0	-1.7	-0.3	0.3	1.1
Intermittent access intake day 1-15 change	0.3	0.7	1.9	-1.4	0.4	-0.4	-0.8
Intermittent access intake escalation	0.2	0.5	1.7	-1.3	0.2	-0.2	-0.3
Intermittent access intake escalation 2	0.1	0.1	0.3	-0.5	-0.2	0.2	-0.0
Intermitt. access day 1 inactive lever presses	0.1	0.5	1.4	-1.2	0.0	0.0	0.7
Intermitt. access day 15 inactive lever presses	0.5	1.0	1.7	1.3	-1.0	1.0	0.6
Intermitt. access escalation Index	0.1	0.1	0.3	0.6	-0.1	0.1	0.2
Intermittent access day 1 total infusions	1.1	1.8	2.7	0.6	1.7	-1.6	-1.1
Intermittent access day 15 total infusions	0.9	1.4	1.9	-0.7	1.4	-1.4	-1.1
Intermittent access terminal intake (last 3 days)	0.4	0.5	0.8	0.1	0.9	-0.9	-0.7
Intermittent access total infusions	0.6	0.8	1.3	0.3	1.2	-1.2	-0.5
Intermittent access day 1 locomotion	0.3	0.4	0.6	0.5	0.8	-0.8	-0.1
Intermittent access day 15 total locomotion	1.1	1.9	2.6	1.0	1.6	-1.6	-1.2
Intermittent access total locomotion	0.9	1.1	1.8	0.9	1.3	-1.3	-0.1
Intermittent access standard deviation	0.1	0.2	0.5	-0.7	-0.4	0.4	0.2
Left kidney weight	1.8	8.6	29.9	-5.5	-1.3	1.3	0.9
Right kidney weight	2.1	9.6	31.8	-5.6	-1.4	1.5	1.6
Cocaine induced anxiety	0.2	0.3	0.9	0.9	-0.1	0.1	-0.6
Post-drug Anxiety	0.9	1.0	3.3	1.8	-0.6	0.6	-0.1
Baseline Anxiety	0.7	0.8	1.1	0.7	-0.9	0.9	1.0
Tail length	3.3	12.8	21.3	-4.6	3.0	-2.9	-3.5
Length with tail	3.2	14.0	48.7	-7.0	1.3	-1.2	-2.1
Length without tail	2.9	9.4	28.1	-5.3	-1.9	1.9	1.6
Times rat made contact with spout	0.8	0.9	1.7	-0.5	1.3	-1.3	-0.5
Lifetime Intake	0.5	0.6	1.1	0.3	1.0	-1.0	-0.2
Liver weight, left	1.0	1.7	6.4	-2.5	-0.4	0.4	-0.3
Liver weight, right	0.9	1.5	6.0	-2.4	0.1	-0.1	0.3
Locomotor activity	0.5	0.8	2.0	-1.4	0.3	-0.3	-1.1
Locomotor testing distance	0.2	0.3	0.8	-0.9	-0.5	0.5	0.2
Locomotor testing rearing	0.1	0.1	0.2	0.1	-0.4	0.4	-0.4
Locomotion in novel chamber	5.6	7.2	13.0	-0.3	3.6	-3.6	-1.6
Locomotion in novel chamber post-restriction	3.0	4.8	8.5	-1.3	2.9	-2.9	-0.8
Fecal boli incidents, locomotor time 1	0.6	0.9	3.4	-1.8	-0.1	0.1	-0.4
Change in fecal boli incidents, locomotor task	0.6	0.6	2.0	1.4	-0.0	0.0	0.5
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.6	0.4	0.2	-0.1	0.8
Bouts of movement, locomotor time 1	0.0	0.0	0.1	-0.1	0.1	-0.1	-0.4
Total resting periods, locomotor time 1	0.0	0.0	0.0	0.1	-0.0	0.0	0.0
Rest time, locomotor task time 1	0.4	0.4	0.9	0.2	0.9	-0.9	0.0
Distance moved, locomotor task time 1	0.1	0.1	0.2	-0.1	-0.4	0.4	0.1
Vertical activity count, locomotor time 1	0.2	0.4	0.5	-0.4	-0.7	0.7	0.6
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.2	-0.2	-0.2	0.2	-0.4
Bouts of movement, locomotor time 2	0.9	1.5	5.7	-2.4	-0.2	0.2	-0.3
Total resting periods, locomotor time 2	0.8	1.5	5.3	-2.3	-0.5	0.5	0.3
Rest time, locomotor task time 2	0.2	0.3	0.7	0.9	0.3	-0.2	0.5
Distance moved, locomotor task time 2	0.2	0.2	0.5	-0.7	0.3	-0.3	-0.5
Vertical activity count, locomotor time 2	0.4	0.6	2.1	-1.4	-0.1	0.1	0.5
Light reinforcement 1	0.3	0.6	1.6	1.3	-0.3	0.3	0.9
Light reinforcement 2	0.7	1.1	3.0	0.2	-0.8	0.8	1.7
Bone: marrow area	0.6	1.3	2.3	-1.5	1.1	-1.1	-0.9
Bone: maximum diameter	0.6	1.0	3.9	-2.0	-0.3	0.3	0.1
Bone: maximum force	0.1	0.2	0.4	-0.6	0.3	-0.3	-0.3
Bone: maximum moment	0.1	0.2	0.4	-0.6	0.3	-0.3	-0.0
Mean time between licks in bursts	0.1	0.2	0.7	-0.1	0.4	-0.4	-0.8
Mean num. licks in bursts	0.2	0.3	0.8	0.9	0.1	-0.1	-0.5
Cd content in liver	0.8	0.9	1.6	-0.4	1.2	-1.2	-0.6
Co content in liver	1.0	1.1	1.7	0.9	1.3	-1.3	-0.5
Cu content in liver	0.7	0.9	1.6	-0.5	-1.3	1.2	0.3
Fe content in liver	4.4	5.3	7.9	-2.1	-2.8	2.8	1.1
K content in liver	0.1	0.1	0.1	0.1	0.3	-0.3	0.2
Mg content in liver	0.4	0.4	0.9	0.8	0.2	-0.2	-1.0
Mn content in liver	0.4	0.4	0.6	-0.6	0.7	-0.7	-0.4
Na content in liver	0.1	0.1	0.2	-0.4	0.2	-0.2	0.4
Rb content in liver	2.1	2.4	6.0	2.4	-1.4	1.4	-0.3
Se content in liver	3.3	3.9	5.7	0.3	-2.2	2.2	2.4
Sr content in liver	1.3	1.1	2.3	-1.5	0.9	-0.9	-0.6
Zn content in liver	1.2	1.4	5.1	-2.3	-0.1	0.1	0.6
Bone: minimum diameter	0.0	0.0	0.1	0.1	0.1	-0.1	-0.3
Time in familiar zone, hab. session 1	0.3	0.3	0.7	-0.5	-0.3	0.3	0.8
Time in novel zone, hab. session 1	0.3	0.3	0.6	-0.6	-0.2	0.2	-0.8
Total zone transitions, hab. session 1	3.9	5.5	7.9	0.2	2.8	-2.8	-2.5
Total locomotion distance, hab. session 1	1.1	1.5	2.5	1.1	1.1	-1.1	-1.6
Locomotion velocity, hab. session 1	1.4	1.9	3.5	1.9	1.1	-1.1	-1.3
Time in familiar zone, hab. session 2	1.9	2.0	3.9	-0.0	-2.0	2.0	-0.0
Time in novel zone, hab. session 2	0.9	0.9	1.7	0.4	1.3	-1.3	0.1
Total zone transitions, hab. session 2	3.3	4.3	8.4	-0.6	2.9	-2.9	-0.3
Total locomotion distance, hab. session 2	1.8	2.4	4.7	0.5	2.2	-2.2	-0.2
Locomotion velocity, hab. session 2	2.0	2.7	5.3	0.5	2.3	-2.3	-0.1
Novel to familiar place preference ratio	0.1	0.2	0.2	-0.1	0.5	-0.5	0.4
Novelty place preference	0.1	0.1	0.2	-0.2	0.2	-0.2	0.5
Time in novel zone, NPP test	0.1	0.1	0.3	-0.5	0.2	-0.2	0.6
Total zone transitions, NPP test	1.8	2.5	4.2	-1.1	2.0	-2.0	-0.8
Total locomotion distance, NPP test	0.9	1.3	2.2	0.6	1.5	-1.5	-0.6
Locomotion velocity, NPP test	1.6	2.2	3.5	0.7	1.9	-1.9	-1.2
Intraocular pressure	0.4	0.6	0.8	-0.9	-0.9	0.9	-0.3
Delta distance traveled before/after self-admin	2.0	2.1	3.4	-0.2	1.6	-1.6	-1.8
Delta ambulatory time before/after self-admin	0.8	1.0	1.9	0.1	1.0	-1.0	-1.4
Parametrial fat weight	0.5	1.2	2.3	-1.5	-1.1	1.1	0.4
Pavlov. Cond. lever latency	1.7	2.1	3.7	-1.9	-1.2	1.2	1.4
Pavlov. Cond. magazine entry latency	2.0	2.6	3.5	0.1	1.9	-1.9	-1.8
Pavlov. Cond. change in total contacts	0.6	0.6	1.3	1.0	0.2	-0.2	-1.2
Pavlov. Cond. index score	1.5	1.9	2.8	1.1	1.4	-1.4	-1.7
Pavlov. Cond. latency score	1.9	2.4	2.7	1.2	1.6	-1.6	-1.6
Pavlov. Cond. lever contacts	2.1	2.5	4.8	2.2	1.1	-1.1	-1.6
Pavlov. Cond. magazine entry number	1.8	2.3	4.9	-0.3	-1.4	1.4	2.2
Pavlov. Cond. intertrial magazine entries	0.3	0.4	1.3	0.1	-0.4	0.4	1.2
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	2.2	1.1	1.1	-1.1	-1.5
Pavlov. Cond. response bias	1.7	2.1	4.2	0.8	1.4	-1.4	-2.0
Pavlov. Cond. lever latency	0.2	0.2	0.5	-0.7	0.1	-0.1	0.6
Pavlov. Cond. magazine entry latency	0.0	0.0	0.1	-0.1	-0.1	0.1	-0.3
Pavlov. Cond. change in total contacts	0.1	0.2	0.5	-0.4	0.1	-0.1	-0.7
Pavlov. Cond. index score	0.1	0.2	0.5	0.1	0.3	-0.3	-0.7
Pavlov. Cond. latency score	0.1	0.2	0.5	0.1	0.2	-0.2	-0.7
Pavlov. Cond. lever contacts	0.2	0.3	0.9	1.0	-0.3	0.3	-0.4
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	-0.1	0.2	-0.2	0.5
Pavlov. Cond. intertrial magazine entries	0.3	0.5	0.9	0.2	0.9	-0.9	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.6	-0.0	0.3	-0.3	-0.8
Pavlov. Cond. response bias	0.3	0.4	1.0	1.0	-0.3	0.3	-0.6
Time in closed arm before self-admin	0.9	1.2	3.4	-1.8	0.8	-0.8	-0.1
Time in closed arm after self-admin	2.1	2.3	6.4	-2.5	1.0	-1.0	-0.8
Time in open arm before self-admin	0.0	0.1	0.1	-0.3	-0.1	0.1	-0.3
Time in open arm after self-admin	1.0	1.1	4.3	2.1	0.0	-0.0	-0.3
Bone: periosteal estimation	0.4	0.7	2.7	-1.6	0.3	-0.3	-0.3
Bone: periosteal perimeter	0.5	0.8	2.0	-1.4	-0.8	0.8	0.3
Bone: post-yield work	0.2	0.2	0.3	0.3	-0.6	0.5	0.6
Progressive ratio test 1 active lever presses	0.9	1.2	1.5	-0.9	1.2	-1.2	-0.9
Progressive ratio test 1 breakpoint	0.9	1.1	1.5	-0.9	1.2	-1.2	-1.0
Progressive ratio test 1 inactive lever presses	0.3	0.4	0.5	-0.7	0.7	-0.7	-0.2
Progressive ratio test 2 active lever presses	1.9	2.3	3.6	-1.4	1.9	-1.9	-0.1
Progressive ratio test 2 breakpoint	1.9	2.1	3.4	-1.4	1.8	-1.8	-0.1
Progressive ratio test 2 inactive lever presses	1.0	1.6	2.1	-1.5	1.4	-1.3	-0.6
Incentive Sensitization - Responses	0.8	1.1	1.8	-0.7	1.3	-1.3	0.7
Incentive Sensitization - Breakpoint	0.9	1.1	1.8	-0.6	1.4	-1.3	0.7
Sum of active levers in priming session hrs 5-6	0.3	0.3	1.2	-1.1	0.1	-0.1	-0.0
Progressive ratio	0.2	0.3	0.5	0.4	0.7	-0.7	-0.1
Food seeking constrained by brief footshock	0.5	0.6	1.3	-0.8	-0.5	0.5	1.1
Seeking ratio, punishment vs. effort	0.3	0.4	1.5	-1.2	-0.2	0.2	0.3
Retroperitoneal fat weight	1.3	5.4	8.4	-1.9	-2.9	2.9	1.0
Reaction time number correct	0.5	1.0	2.5	-1.6	0.8	-0.8	0.6
Reaction time mean minus median	1.9	4.8	13.7	1.6	1.3	-1.3	-3.7
Reaction time mean minus median AUC	2.0	5.1	14.0	1.9	1.1	-1.1	-3.7
Reaction time num false alarms	0.2	0.3	0.4	-0.2	0.7	-0.7	0.5
Reaction time num false alarms AUC	0.1	0.1	0.4	-0.1	0.0	-0.0	0.6
Reaction time trials correct on left	0.5	1.0	2.5	-1.6	0.8	-0.8	0.6
Reaction time trials on left	0.5	1.0	2.4	-1.5	0.9	-0.8	0.5
Reaction time mean	1.5	2.4	7.8	2.8	-0.2	0.2	-1.3
Reaction time mean AUC	1.5	2.4	7.2	2.7	-0.3	0.3	-1.5
Median of all reaction times	1.5	2.2	7.5	2.7	-0.8	0.8	-0.2
Reaction time omissions	0.6	0.9	2.3	1.1	0.1	-0.1	-1.5
Reaction time false alarm rate	0.1	0.2	0.2	0.5	-0.4	0.4	0.3
Reaction time premature initiation rate	3.8	5.2	6.4	2.5	2.3	-2.3	-2.0
Reaction time premature initiations	2.6	4.6	6.5	1.4	2.6	-2.6	-1.8
Std. dev. reaction times	2.1	3.8	9.9	2.1	0.7	-0.7	-3.1
Reaction time trials completed	0.5	1.0	2.4	-1.5	0.9	-0.8	0.5
Reaction time trials AUC	0.5	0.9	2.3	-1.5	0.7	-0.6	0.7
Run reversals in cocaine runway, females	0.4	0.4	1.5	1.2	0.0	-0.0	0.0
Run reversals in cocaine runway, males	0.5	0.5	1.4	-1.2	-0.5	0.5	0.5
Latency to leave start box in cocaine runway	2.8	3.1	6.1	0.6	-2.5	2.5	0.1
Latency to leave start box in cocaine runway, F	2.9	3.3	6.5	-0.4	-2.5	2.6	0.3
Latency to leave start box in cocaine runway, M	0.2	0.2	0.4	0.6	-0.1	0.1	-0.6
Std. dev. time between licks in bursts	0.0	0.1	0.1	0.2	0.3	-0.3	0.2
Total sessions with >9 infusions	0.4	0.5	1.6	-1.3	0.2	-0.2	0.5
Short access day 1 total inactive lever presses	0.7	0.9	3.0	-1.7	0.4	-0.4	-0.4
Short access day 10 total inactive lever presses	0.1	0.2	0.3	-0.5	-0.5	0.5	0.5
Short access day 1 total infusions	0.3	0.4	1.0	-1.0	0.4	-0.4	0.5
Short access day 10 total infusions	0.3	0.4	0.7	-0.3	0.9	-0.9	-0.3
Short access total infusions	0.2	0.2	0.4	0.0	0.6	-0.6	0.4
Short access day 1 locomotion	0.3	0.4	0.8	-0.9	0.6	-0.6	0.3
Short access day 10 total locomotion	0.3	0.6	1.9	-1.4	-0.3	0.3	0.3
Short access total locomotion	0.1	0.1	0.2	-0.5	0.4	-0.4	0.1
One hour access (0.3 mA shock)	2.2	2.5	4.4	-0.2	2.1	-2.1	-1.1
Compulsive drug intake	0.9	1.0	3.9	2.0	0.2	-0.2	-0.3
One hour access (shock baseline)	0.7	1.1	1.8	-0.8	1.3	-1.3	-0.6
Social response proportion	2.2	2.5	5.4	-1.2	1.2	-1.2	-2.3
Social responses	3.2	4.1	12.4	-0.1	1.4	-1.4	-3.5
Social time	0.6	0.9	2.0	1.4	-0.5	0.4	-1.0
Soleus weight	0.5	1.4	3.5	-1.9	-0.9	0.9	-0.4
Bone: stiffness	0.0	0.1	0.1	0.1	0.2	-0.2	-0.3
Tibialis anterior weight	0.9	3.2	12.0	-3.5	0.2	-0.2	-0.8
Time to tail flick, vehicle, before self-admin	0.4	0.4	0.8	0.4	-0.9	0.9	0.1
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.3	-0.4	-0.5	0.5	0.1
Time to tail flick, test, before self-admin	0.9	0.9	3.4	-1.8	0.4	-0.4	0.0
Time to tail flick, test, after self-admin	0.8	0.8	0.9	0.9	-0.9	0.9	0.8
Delta time to tail flick, vehicle, before/after SA	0.7	0.6	1.1	0.0	-0.8	0.8	1.1
Delta time to tail flick, test, before/after SA	0.9	0.9	3.2	1.8	-0.3	0.3	0.4
Tibia length	0.7	2.0	7.7	-2.8	-0.1	0.1	-0.5
Ambulatory time before self-admin	0.4	0.6	0.9	0.6	-0.8	0.8	0.9
Ambulatory time after self-admin	0.1	0.1	0.2	0.4	-0.0	0.0	-0.5
Bone: tissue strength	1.1	1.1	2.1	-1.4	-0.2	0.2	1.5
Total heroin consumption	0.4	0.5	2.0	1.4	-0.0	0.0	-0.2
Bone: trabecular number	1.4	2.4	7.3	-2.7	-0.9	1.0	0.7
Bone: trabecular spacing	0.6	0.8	1.9	1.4	-0.6	0.6	0.8
Bone: trabecular thickness	2.2	2.7	5.2	-2.3	-1.2	1.2	1.7
Bone: trabecular tissue density	0.6	0.9	1.3	0.7	-1.1	1.1	0.7
Water consumed over 24 hours	1.3	1.8	2.9	-1.1	1.7	-1.7	-0.3
Number of responses in last shaping day	0.2	0.2	0.2	-0.5	-0.4	0.4	0.4